Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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attenuation of acute inflammatory effects of silica in rat lung by 21-aminosteroid, u74389g. | chemical alteration of the glucocorticoid, methylprednisolone, has led to the introduction of a new class of compounds called the 21-aminosteroids (21-ass). the purpose of this study was to investigate the effect of the 21-as, u74389g, on silica-induced acute lung injury. male fischer 344 rats were treated intraperitoneally with saline or u74389g in a total dose of 15 mg/kg divided into three injections of 5 mg/kg separated by 4 h. following the first treatment, animals from the two groups were ... | 1995 | 7705890 |
nematocera (ceratopogonidae, psychodidae, simuliidae and culicidae) and control methods. | the biology, veterinary importance and control of certain nematocera are described and discussed. culicoides spp. (family ceratopogonidae) transmit the arboviruses of bluetongue (bt), african horse sickness (ahs), bovine ephemeral fever (bef) and akabane. some other arboviruses have been isolated from these species, while fowl pox has been transmitted experimentally by culicoides. these insects are vectors of the parasitic protozoans leucocytozoon caulleryi and haemoproteus nettionis, and the pa ... | 1994 | 7711309 |
practical questions about therapy of hypertension with ace inhibitors. j. scholze, berlin, on the 24-hour effect, possible combinations and side-effects of ace inhibitors--ass/antirheumatic agents. | 1995 | 7713469 | |
[effects of the leaves of acanthopanax senticosus (rupr. et maxim.) harms. on myocardial infarct size in acute ischemic dogs]. | effects of saponin isolated from the leaves of acanthopanax senticosus (ass) on myocardial infarct size were studied in acute ischemic dogs. the results showed that ass (in a dosage of 25.50 mg/kg, iv) could significantly reduce the sizes of acute myocardial infarcts and decline the serum ck and ldh activity at 6h after ligation of lad. it could also decrease the serum ffa levels at 3h and 6h after lad occlusion. | 1994 | 7718140 |
6 alpha-biotinylated estrone: novel tracer in competitive chemiluminescence immunoassay of estrone in serum. | we describe the development and validation of a labeled-hapten competitive immunoassay for determining total estrone in serum. for the hapten tracer we use the 6 alpha-biotinylated estrone derivative, 3-hydroxyestra-1,3,5(10)-trien-17-one 6 alpha-n-(epsilon-biotinyl)aminocaproamide (bio-e1). a specific polyclonal rabbit anti-estrone antibody is indirectly bound via an immobilized donkey anti-rabbit antibody on microtiter plate wells. the amount of bio-e1 bound is then measured with streptavidin- ... | 1995 | 7720247 |
equine parafilariosis in iran. | from march to september 1991, horses (n = 1567), donkeys (n = 112) and mules (n = 96) were examined for equine parafilariosis by random sampling from different areas of iran. the clinical signs of equine parafilariosis were observed in 136 cases of two northern areas (1.4% and 41.3% infection rate) and one northeastern area (6.3% infection rate). most of the infected cases were confirmed by laboratory findings. all infected cases were followed up to establish the epidemiological features. the re ... | 1995 | 7732643 |
optimization and validation of an elisa to measure specific guinea pig igg1 antibody as an alternative to the in vivo passive cutaneous anaphylaxis assay. | assessment of the allergenic potency of enzymes involves the use of a guinea pig model in which specific igg1 antibody titers are used as the endpoint. the in vivo passive cutaneous anaphylaxis (pca) assay is used to measure specific igg1 antibody. this report describes the development and validation of an enzyme-linked immunosorbent assay (elisa) to measure guinea pig specific igg1 antibody as an in vitro alternative to the pca assay. cross reactivity of various rabbit and mouse (monoclonal) an ... | 1995 | 7737435 |
neonatal isoerythrolysis in mule foals. | four mule foals received anti-rbc antibody from their dam's colostrum. two foals developed anemia, 1 developed severe thrombocytopenia, and 1 did not develop any clinical or laboratory abnormalities. all foals had the same donkey sire. seven mares, including the dams of foals 1 to 4, bred to the donkey sire produced anti-rbc antibody. two mares produced anti-rbc antibody to the donkey rbc on the first mating. the donkey sire and 18 of its offspring were found to have an rbc antigen unique to mul ... | 1995 | 7744666 |
transport-induced stress responses in fed and fasted donkeys. | plasma endocrine and metabolic responses to transport for 30 minutes and four hours were investigated in six fed donkeys. in the unstressed animals there was a pulsatile secretion of cortisol at two-hour intervals, from minima of 51.4 +/- 17.6 nmol litre-1 to maxima of 160.0 +/- 11.0 nmol litre-1, but during transport this pulsatility was lost and the animals' stress response was characterised by steady high concentrations of 110 to 220 nmol litre-1. the cortisol concentration decreased after th ... | 1995 | 7761693 |
clinical, virological and serological responses of donkeys to intranasal inoculation with the ky-84 strain of equine arteritis virus. | the clinical, virological and serological responses of seven female donkeys (equus asinus) to inoculation with the ky-84 strain of equine arteritis virus (eav), a strain that causes moderate to severe clinical signs in horses, was investigated. in the donkeys, the only clinical signs observed were fever (mainly 3-9 days after inoculation), mild depression in four animals, and a slight nasal or ocular discharge in three. all of the donkeys became infected with eav as shown by recovery of the viru ... | 1995 | 7769149 |
equine viral arteritis in donkeys in south africa. | 1994 | 7776331 | |
serological relationship between a donkey alphaherpesvirus (isolate m7/91) and equid herpesvirus type 1 and 4. | rabbit hyperimmune serum prepared against a donkey alphaherpesvirus isolate (m7/91), and against ehv-1 and ehv-4 was used to characterise the antigenic relationship between these 3 viruses. serum from immunised rabbits was always more specific for homologous virus and showed different cross reactivity for heterologous virus. it was concluded that the immunologic relationship between the m7/91 isolate and ehv-1, was closer than that between this isolate and ehv-4. a serological survey of donkeys ... | 1994 | 7776336 |
second locus for hirschsprung disease/waardenburg syndrome in a large mennonite kindred. | we have studied a large mennonite kindred in which 20 members were affected with hirschsprung disease (hscr), 5 of whom had one or more manifestations of waardenburg syndrome (ws) type ii (ws2). eleven additional relatives had signs of ws2 without hscr. since hscr and ws2 each represent perturbations of neural crest migration/differentiation, this large pedigree with apparent cosegregation of hscr and ws2 offered an opportunity to search for linkage between these loci, candidate genes, and rando ... | 1994 | 7802041 |
[degradation of the constituents in solubilization process of donkey skin]. | dry donkey skin, defatted in advance with hair scraped off, was separately solubilized by heating in sealed tubes at 130 degrees c for 2, 4, 6, 8h. the resultants were clarified and dried as ejiao, whose yield appeared to reach maximum after 4h heating. absorptivities of all four ejiao preparations were in good approximation to standard gelatin. however, their intrinsic viscosity declined in order of prolonged solubilization process, indicating that depolymerization of donkey skin gelatin had ta ... | 1994 | 7811366 |
alterations in glomerular anionic sites in canine anti-glomerular basement membrane nephritis with onset of severe proteinuria. | rabbit anti-glomerular basement membrane serum (agbm) or normal rabbit serum (nrs) were given intravenously (2 ml/kg body weight) to 8 male beagle dogs. light and transmission electron microscopy and immunofluorescence were performed on the kidneys on day 7 postinjection. alterations of anionic sites (ass) of glomerular basement membrane (gbm) in peripheral, proximal, and paramesangial portions were studied quantitatively by electron microscopy using polyethyleneimine (pei; molecular weight = 1, ... | 1994 | 7817121 |
linkage analysis of the nail-patella syndrome. | nail-patella syndrome (nps) is an autosomal dominant disorder characterized by dysplasia of nails and patella, decreased mobility of the elbow, iliac horns, and, in some cases, nephropathy. the disorder has been mapped to the long arm of chromosome 9, but the precise localization and identity of the nps gene are unknown. linkage analysis in three nps families, using highly informative dinucleotide repeat polymorphisms on 9q33-q34, confirmed linkage of nps to this chromosome. recombinations were ... | 1995 | 7825584 |
effect of increasing work rate on metabolic responses of the donkey (equus asinus). | oxygen consumption (vo2) and concentration of venous blood metabolites were measured in donkeys trained to run and to pull loads on a treadmill. vo2 in two donkeys running at maximal speed on a 9.8% slope was 110 +/- 2 ml.min-1.kg-1, approximately 22 times preexercise vo2. average heart rate at maximal vo2 (vo2max) was 223 +/- 2 beats/min, five times the preexercise heart rate. blood lactate increased 14-fold, and blood glucose did not change (p > 0.05). animals running up a 4% incline and incre ... | 1994 | 7836149 |
hyperlipemia in 9 miniature horses and miniature donkeys. | the medical records from 9 consecutive miniature horses (n = 5) and miniature donkeys (n = 4) with hyperlipemia (serum triglyceride concentration > 500 mg/dl) were reviewed. in all cases, hyperlipemia was a secondary complication of a primary systemic disease including septicemia, colitis, parasitism, esophageal obstruction, gastric impaction and rupture, fecalith, and pituitary adenoma. therapy consisted of specific treatment for the primary disease, supportive care, and nutritional support. th ... | 1994 | 7837116 |
village health survey of sina mala, gongola state, nigeria. | a survey of the environment, life-style, and health status, knowledge, attitudes and practices in the village of sina mala was carried out prior to the introduction of a village health post by a church-run rural health programme. in addition to the perceived needs of the villagers for a school, easier access to medicine and external assistance with well drilling, the study identified the need to train traditional midwives in hygienic delivery, to make local health workers more aware of onchocerc ... | 1993 | 7839910 |
frequency and morpho-structural organization of the thyroid gland isthmus in horses, donkeys and small ruminants. | 1994 | 7840946 | |
hosts of lutzomyia shannoni (diptera: psychodidae) in relation to vesicular stomatitis virus on ossabaw island, georgia, u.s.a. | hosts of lutzomyia shannoni dyar, a suspected biological vector of the new jersey serotype of vesicular stomatitis (vsnj) virus, were determined using an indirect enzyme-linked immunosorbent assay (elisa) of 333 blood-fed female sandflies collected from their diurnal resting shelters on ossabaw island, georgia, u.s.a. sandflies had fed primarily on white-tailed deer (odocoileus virginianus) (81%) and to a lesser extent on feral swine (sus scrofa) (16%), two species of host infected annually with ... | 1994 | 7841487 |
postmitotic oligodendrocytes generated during postnatal cerebral development are derived from proliferation of immature oligodendrocytes. | the phenotype of proliferating glia is examined during postnatal rodent development by combining immunocytochemistry (icc) with 3h-thymidine autoradiography (arg) to identify cells in the s phase of the cell cycle. antibodies (abs) which are specific for cells in the oligodendrocyte (ol) lineage were utilized, with emphasis placed upon the proliferation of ols as it remains unclear whether this cell type divides in situ. the results show that proliferating cells stain with abs which are specific ... | 1994 | 7843784 |
effect of d-ala-d-beta nal-ala-trp-d-phe-lys-nh2 (kp-102) on gh secretion in urethan-anesthetized rats. | the effect of a newly developed growth hormone (gh)-releasing hexapeptide (kp-102) on gh secretion was studied in urethan-anesthetized adult male rats. although kp-102 alone exerted a small influence on gh secretion, it produced a large plasma gh response in the presence of exogenous gh-releasing factor (grf). during the continuous infusion of grf, the somatotropes became refractory to a large bolus dose of grf, but kp-102 induced a marked increase of plasma gh. the gh response to kp-102 alone o ... | 1994 | 7846295 |
detection, cloning and characterisation of papillomaviral dna present in sarcoid tumours of equus asinus. | molecular investigations on 18 naturally occurring sarcoid tumors removed from donkeys identified papillomaviral dna homologous to bovine papillomavirus (bpv)-2 dna under stringent conditions, in all the samples. restriction endonuclease analysis of 15 of the tumours demonstrated papillomaviral dna similar to bpv-1 and bpv-2. the type of dna was not specific to either the site or the type of lesion. the analysis of the nucleotide base sequence of a cloned papillomaviral element from a sarcoid sh ... | 1994 | 7846835 |
workshop summary: donkey parasitology. | 1994 | 7846859 | |
the tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. | we have previously demonstrated allele loss in hamartomas from patients with tuberous sclerosis for markers spanning the tuberous sclerosis gene on chromosome 16q13.3 (tsc2). germline deletions in the tsc2 gene have been shown in 5% of patients with tuberous sclerosis (tsc). these data support our hypothesis that the tsc2 gene acts as a growth suppressor gene, analogous to the traditional tumour suppressor gene. we now report a tsc hamartoma showing allele loss for markers on chromosome 9q34 in ... | 1994 | 7849709 |
enhanced sensitivity to neutralizing antibodies in a variant of equine infectious anemia virus is linked to amino acid substitutions in the surface unit envelope glycoprotein. | serial passage of the prototype (pr) cell-adapted wyoming strain of equine infectious anemia virus (eiav) in fetal donkey dermal (fdd) rather than fetal horse (designated fetal equine kidney [fek]) cell cultures resulted in the generation of a variant virus strain which produced accelerated cytopathic effects in fdd cells and was 100- to 1,000-fold more sensitive to neutralizing antibodies than its parent. this neutralization-sensitive variant was designated the fdd strain. although there were d ... | 1995 | 7853482 |
specific restrictions in the progression of venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins. | the pathogenesis of venezuelan equine encephalitis virus (vee) was examined in the mouse model using v3000, a virus derived from a molecular clone of the trinidad donkey strain of vee. these results were compared in parallel experiments with avirulent mutants of vee derived by site-directed mutagenesis of the clone. adult mice, inoculated subcutaneously in their left rear footpad with v3000, were followed in a time course study for 6 days in which 15 organs were tested for histopathological chan ... | 1995 | 7856110 |
sequence analyses of the p24 gene of borna disease virus in naturally infected horse, donkey and sheep. | by reverse transcriptase/pcr amplification and subsequent sequence determination of the p24 gene, the relatedness of borna disease virus (bdv) in various naturally infected animal species was determined. these results are indicative of a common ancestral virus pool and a remarkably low species barrier of bdv. comparison of 11 sequences to that of tissue culture adapted virus revealed that the homology among all isolates was at least 96.2% at the nucleotide level, and 97% at the amino acid level. ... | 1994 | 7856315 |
morphometric analysis of sardinian breed donkeys. | the main somatometric characteristics of 15 sardinian breed adult donkeys (6 male and 9 female) were studied. analysis of the somatic measurements and zoometric indexes show subjects of small build of a mesomorph constitutional type. dimorphism between the sexes is slight and is limited to the rump area. the number of donkeys still to be found in sardinia is greatly reduced and urgent measures are needed to safeguard its animal genetic resource. | 2003 | 7857604 |
effect of chronic renal failure on the abundance of mrna for enzymes of intermediary metabolism in kidney and liver. | in chronic renal failure (crf), renal ammoniagenesis and handling of ornithine cycle intermediates (ornithine, citrulline, and arginine) are disturbed. the present study examined the molecular mechanisms of these disturbances in kidney and liver of rats with moderate crf induced by 5/6 nephrectomy. the steady state level of mrna for phosphoenolpyruvate carboxykinase (pepck) and argininosuccinate synthetase (ass) in both kidney and liver were unaffected by crf. on the other hand, that for phospha ... | 1994 | 7859037 |
children's informed consent to treatment: is the law an ass? | 1994 | 7861423 | |
the primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin. | two primary serine proteinase inhibitors in goat plasma have been isolated and characterized. the n-terminal sequence analysis of the purified proteins revealed that they are closely related to each other and are highly homologous to human alpha 1-anti-chymotrypsin rather than alpha 1-proteinase inhibitor. however, despite structural similarities the inhibitory specificity of the goat inhibitors differed from each other and from that of anti-chymotrypsin. in contrast with human anti-chymotrypsin ... | 1995 | 7864809 |
malaria vaccine research. | in our report "activation of raf as a result of recruitment to the plasma membrane" (3 june, p. 1463) (1), panels e and f of figure 1 on page 1464 were incorrect. the correct photographs appear below. in addition, the [see figure in the pdf file] second sentence of the legend to figure 1 should have read, "the raf constructs were tagged at the cooh-terminus with a glu-glu epitope (meympme) (24) for c-raf, or at the nh(2)-terminus with both the glu-glu and the myc (meqkliseedl) (23) epitopes for ... | 1994 | 7864993 |
ultrastructure of the hinny (equus asinus x equus caballus) seminiferous epithelium. | the gonads and the germinative cells of 3 male hinnies were studied with light and transmission electron microscopy with the aim to observe the development of germ cells and verify the morphological modifications due to the hybridization. the hinny seminiferous epithelium presented sertoli cells and spermatogonia with normal features and anomalous spermatocytes i. the other cells from the spermatogenic sequence were not seen. most of the alterations began to occur in the cytes i, which presented ... | 1994 | 7887486 |
[hypoglycemic effect of saponin isolated from leaves of acanthopanax senticosus (rupr. et maxin.) harms]. | the hypoglycemic effect of saponin isolated from the leaves of acanthopanax senticosus (ass) was studied. the results showed that ass(100, 200 mg/kg, ip) could decrease various cases of experimental hyperglycemias induced by injection of adrenaline, glucose and alloxan, without affecting the levels of blood sugar in normal mice. | 1994 | 7893389 |
inhibition of acrosin by serpins. a suicide substrate mechanism. | the serpins antithrombin, protease nexin 1, and alpha 1-antitrypsin with a reactive-center arginine (arg-alpha 1-antitrypsin) were found to inhibit the sperm protease acrosin with varying efficiency. the serpins were titrated against acrosin to determine their specific activity with respect to this enzyme. while antithrombin was fully active against acrosin, more than one molecule of arg-alpha 1-antitrypsin and protease nexin 1 was required to inhibit one molecule of acrosin. in particular, only ... | 1995 | 7893664 |
osteosynthetic reconstruction in a patient with gardner-diamond syndrome. | based on clinical observations in one female patient who suffered from gardner-diamond syndrome, we noticed that surgery can be performed without any bleeding complications, although operations normally are contraindicated in persons with this condition. additionally, a correlation seems to exist between ass and sexual and hormonal maturity. | 1995 | 7897725 |
allosteric effects of the alkane-bis-ammonium compound w84 and of tacrine on [3h]pirenzepine binding at m1-receptors in rat cerebral cortex. | the bis-quaternary w84, hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)-ammonium bromide], is a potent allosteric modulator of m2-cholinoceptors. in this study we aimed at quantifying its allosteric effect on the dissociation of [3h]pirenzepine from m1-cholinoceptors in rat cerebral cortex and to measure the effects on association and equilibrium binding of [3h]pirenzepine. for sake of comparison tacrine was included which is known to be a potent allosteric modulator of [3h]pirenzepine binding ... | 1994 | 7899262 |
characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay. | a panel of 18 superficial or invasive transitional cell carcinomas (tccs) was analyzed for chromosome 9 deletions by performing a high-density loss of heterozygosity (loh) analysis. twenty-five microsatellite loci were assayed by the polymerase chain reaction (pcr) and 7 restriction fragment length polymorphism (rflp) loci were analyzed by southern blotting. concordant results were obtained with these methods, including direct comparisons at 2 loci. chromosome 9 loh was observed in 13 (72%) of 1 ... | 1993 | 7902161 |
frequency of trypanosomosis and gastrointestinal parasites in draught donkeys in the gambia in relation to animal husbandry. | prevalence of trypanosomosis, gastrointestinal strongyles and level of strongyle egg outputs were studied in relation to husbandry practices in the draught donkey population in the gambia. feeding regime, number of working hours per day and overnight penning practices of donkeys affected significantly (p < 0.05) the level of gastrointestinal strongyle egg output, but not (p > 0.05) trypanosomosis prevalence. dual trypanosome and gastrointestinal strongyle infection significantly reduced the pcv ... | 1994 | 7941024 |
bodyweight changes in pregnant and lactating donkey mares and their foals. | 1994 | 7941264 | |
dust, doctors, donkeys. | 1994 | 7942390 | |
blood protein polymorphisms in the donkey (equus asinus). | transferrin, albumin, 6-phosphogluconate dehydrogenase and vitamin d-binding protein polymorphisms were detected in 242 feral and domesticated australian donkeys by polyacrylamide gel electrophoresis, starch gel electrophoresis, autoradiography, immunoblotting with specific antisera and activity staining. all four tf and two alb variants were donkey specific while only one of the pgd variants was donkey specific. the two gc variants were electrophoretically identical to the equus caballus f and ... | 1994 | 7943978 |
conformational transitions of duplex and triplex nucleic acid helices: thermodynamic analysis of effects of salt concentration on stability using preferential interaction coefficients. | for order-disorder transitions of double- and triple-stranded nucleic acid helices, the midpoint temperatures tm depend strongly on a +/-, the mean ionic activity of uniunivalent salt. experimental determinations of dtm/d ln a +/- and of the enthalpy change (delta h(o)) accompanying the transition in excess salt permit evaluation of delta gamma, the stoichiometrically weighted combination of preferential interaction coefficients, each of which reflects thermodynamic effects of interactions of sa ... | 1994 | 7948695 |
characteristics of acupuncture meridians and acupoints in animals. | in recent years, an increasing number of studies has been conducted on the biophysical characteristics of the meridians and acupoints in humans and animals. the authors aim to further illustrate the objective existence and superficial locations of the meridians in various species of animals. twelve sheep, ten goats, thirteen pigs, eleven cats, eight rabbits and seven donkeys were used to measure low impedance lines (lils) and high percussion sound lines (hpsls) on the skin surface of the animals ... | 1994 | 7949363 |
seasonal variation in the function of blood monocytes obtained from healthy nonsmokers, asymptomatic smokers, and smokers with chronic bronchitis. | the present study focused on two questions: what effects do cigarette smoking and chronic bronchitis have on the function of the precursors of alveolar macrophages, the blood monocytes? can seasonal variations affect the function of these cells? phagocytic activity (the proportion of yeast-ingesting cells and the mean number of yeast particles per ingesting cell) and metabolism of arachidonic acid [secretion of prostaglandin e2 (pge2) and leukotriene b4 (ltb4) in zymosan-stimulated cultures] wer ... | 1994 | 7954908 |
plasma disposition of amikacin and interactions with gastrointestinal microflora in equidae following intravenous and oral administration. | amikacin was detectable (> 0.02 micrograms/ml) in plasma for 12 h in horses and donkeys and for 8 h in ponies following intravenous (i.v.) administration at a dose rate of 6 mg/kg bodyweight. the elimination half-life (harmonic mean) of amikacin was 2.8, 1.6 and 1.9 h in horses, ponies and donkeys, respectively, and the mean body clearance was relatively slow (45.2, 82.4 and 58.0 ml/h.kg, respectively). a suitable dosage interval for the i.v. administration of amikacin sulphate to horses, ponies ... | 1994 | 7966549 |
recent advances in the preparation and storage of red cells. | the policy of blood collection for transfusion and the supply of fractionated plasma products differ between countries which has a strong impact on the choice of methods for rbc preparation and storage. separation into components and storage of red cells in ass are commonly used. new methods for improved preparation have been developed, allowing better standardization of the blood components. several new compositions of as have been described which improve quality with respect to oxygen affinity ... | 1994 | 7975501 |
ultrastructure of the epithelium that lines the ductuli efferentes in domestic equidae, with particular reference to spermatophagy. | the epithelium that lines the ductuli efferentes in the horse, donkey and mule has been examined by electron microscopy. the epithelium consists of columnar ciliated and non-ciliated cells. lymphocytes and macrophages are also present, together with cells that are rich in lipofuscin. these 'lipofuscin-rich' cells are a peculiar feature of the excurrent ducts of equidae and are characterized by a large number of highly heterogeneous residual bodies. the general morphology of the epithelium and, i ... | 1994 | 7976167 |
two loci for tuberous sclerosis: one on 9q34 and one on 16p13. | 32 families informative for the segregation of tuberous sclerosis (tsc) have been examined for genetic markers on chromosomes 9, 11, 12 and 16. in one large family there was clear evidence of linkage to markers on chromosome 16p13.3 (lodscore with d16s291 of 4.7 at theta = 0) but other families were too small to give individually convincing lodscores. combined results for all families gave positive results with abo/dbh on chromosome 9 (max lod 2.63) and with d16s291 on chromosome 16 (max lod 3.9 ... | 1994 | 7979156 |
dystonia in ashkenazi jews: clinical characterization of a founder mutation. | a gene (dyt1) for idiopathic torsion dystonia maps to chromosome 9q34 in ashkenazi jewish families with early onset of symptoms. further, there is linkage disequilibrium between dyt1 and a particular haplotype of alleles at 9q34 loci in this population. this implies that a large proportion of early-onset idiopathic torsion dystonia in ashkenazi jews is due to a founder mutation in dyt1. to characterize the phenotypic range of this mutation, we studied 174 ashkenazi jewish individuals affected wi ... | 1994 | 7979224 |
[characterization and quantification of dermatan sulfate from donkey skin]. | dermatan sulfate (ds), a recently known antithrombotic glycosaminoglycan, was isolated and purified from donkey skin. physiochemical characteristics of the glycan, including constituent analysis, electrophoretic behaviour, molecular mass, specific lyase degradations, ir and pmr spectra were described, using porcine skin-origin dermatan sulfate as a standard reference. contents of ds in donkey skin and its gelatinized preparations (ejiao) were also measured. results indicate that the presence of ... | 1994 | 7980859 |
hyperhomocysteinemia as a possible role for atherosclerosis in capd patients. | it has been shown that hyperhomocysteinemia is a risk factor for atherosclerotic vascular disease. in this study, we measured total plasma homocysteine in continuous ambulatory peritoneal dialysis (capd) patients and evaluated its correlation with atherosclerosis. subjects consisted of healthy volunteers, and hemodialysis (hd) and capd patients. fluoro-hplc was employed to estimate plasma levels of total homocysteine (hcy). plasma levels of total hcy were significantly higher in the capd patient ... | 1994 | 7999846 |
the gene for familial dystonia with myoclonic jerks responsive to alcohol is not located on the distal end of 9q. | a gene (dyt1) for susceptibility to early-onset torsion dystonia in ashkenazi jewish and gentile kindreds is situated on chromosome 9q32-q34 in a 6-7 cm span between markers ak1 and ass. to determine whether transmission of familial dystonia with myoclonic jerks responsive to alcohol was consistent with a gene in this region, we studied the 37 members of a swedish family, of whom 20 were so affected. a lod score of < -2.00 from a two-point linkage analysis with six dna markers covering a 30 cm s ... | 1994 | 8004804 |
characterization of a red blood cell antigen in donkeys and mules associated with neonatal isoerythrolysis. | a red cell antigen of donkeys and mules was identified using antibodies in serum from a mare which produced a mule foal affected with neonatal isoerythrolysis (ni). subsequently antibodies with similar activity were identified in the sera of other mares which had produced mule foals and were produced by immunization of horses with blood from donkeys. the antigen detected by these antibodies does not correspond to any recognized horse red cell alloantigen. this may be a xenoantigen since all donk ... | 1994 | 8010529 |
contractility of lungs and air-tubes: experiments performed in 1840 by charles j.b. williams. | in the 18th century, some medical practitioners considered the main pathological feature of asthma to be the production of mucus. later, during the 19th century, airway smooth muscle contraction was recognized to be a possible cause of airflow obstruction. however, not until 1840 was the contractility of airway smooth muscle clearly established by charles j.b. williams, a famous london physician. in a number of innovative experiments in dogs, rabbits, livestock and even donkeys, he showed: 1) th ... | 1994 | 8013615 |
genetic analysis of nucleotide triphosphatase activity in the mouse brain. | a ca(2+)- or mg(2+)-stimulated ecto-atpase is thought to regulate the hydrolysis of extracellular atp in nervous tissues. the hydrolysis of nucleotide triphosphates (ntps) was analyzed in brain microsomal fractions from crosses of dba/2j (d2) and c57bl/6j (b6) mice. the nucleotide triphosphatase (ntpase) activity was significantly reduced in d2 mice as compared to b6 mice, and b6d2f1 hybrids had activities intermediate to the parentals. a significant positive correlation was found between the hy ... | 1994 | 8056315 |
relationship between plasma insulin and triglyceride concentrations in hypertriglyceridaemic donkeys. | hyperinsulinaemia is a commonly-observed characteristic of insulin resistance, and a reduction in insulin sensitivity is thought to be either a causative and/or symptomatic feature of equine hyperlipaemia. a positive correlation (r = 0.545, p = 0.0015) existed between plasma insulin and triglyceride concentrations determined in 31 donkeys with naturally occurring hyperlipidaemia/hyperlipaemia. greater insulin values tended to occur in the animals with an overweight body score. inter-animal varia ... | 1994 | 8073193 |
animal reservoirs for trypanosoma cruzi infection in an endemic area in paraguay. | animal reservoirs for trypanosoma cruzi infection were investigated in 5 communities in the department of san pedro, currently one of paraguay's most highly endemic areas. a total of 112 domestic animals (37 cattle, 2 horses, 1 ass, 20 pigs, 44 dogs and 8 cats) and 4 wild animals (1 white-eared opossum, 2 yellow armadillos and 1 common long-nosed armadillo) were examined for blood. although no trypomastigotes were found by 2 direct observation methods, the microhaematocrit and giemsa stained thi ... | 1994 | 8075219 |
sequences of two highly divergent canine type c lysozymes: implications for the evolutionary origins of the lysozyme/alpha-lactalbumin superfamily. | the amino acid sequences of two canine lysozymes, from milk and spleen, have been elucidated by direct sequence analyses of the purified proteins and fragments generated from them. the two enzymes are highly divergent, differing from each other by 45% in sequence, but each is closely similar to lysozymes previously obtained from other mammalian species. the milk lysozyme is similar in sequence to equine and donkey milk lysozymes (83% identity) and, like these enzymes, contains a bound ca2+ ion w ... | 1994 | 8080284 |
comparative genetic analysis of swiss and spanish isolates of echinococcus granulosus by southern hybridization and random amplified polymorphic dna technique. | swiss and spanish isolates of echinococcus granulosus were compared using different molecular biological techniques: genomic dnas isolated from parasites originating from various intermediate hosts were subjected to southern hybridization with different probes, the same source of dna was used for dna amplification using the random amplified polymorphic dna (rapd) technique. with both methods the various isolates (metacestodes) of e. granulosus exhibited characteristic banding patterns which allo ... | 1994 | 8087150 |
purified yeast aspartic protease 3 cleaves anglerfish pro-somatostatin i and ii at di- and monobasic sites to generate somatostatin-14 and -28. | anglerfish somatostatin-14 (ss-14) and somatostatin-28 (ass-28) are derived from pro-somatostatin i (apss-i) and pro-somatostatin ii (pss-ii), respectively. purified yeast aspartic protease 3 (yap3), was shown to cleave apss-i at the arg81-lys82 to yield ss-14 and lys-1ss-14. in contrast, yap3 cleaved apss-ii only at the monobasic residue, arg73 to yield ass-28. since the paired basic and monobasic sites are present in both precursors, the results indicate that the structure and conformation of ... | 1993 | 8104828 |
effects of new somatostatin analogs on the cell proliferation of colonic crypts and colonic cancers in rats. | the antiproliferative activity of two new somatostatin (ss) analogs: ass-51 and ass-52 have been tested in this study. we assessed their ability to inhibit the dna synthesis in normal colon crypt cells and in the cells of chemically (dimethylhydrazine)-induced colon cancer in the rats. the incorporation of bromodeoxyuridine (brdu) into appropriate cell nuclei was used as an index of dna synthesis. it was found that: 1) only ass-51 significantly decreases the colon crypt cell proliferation in the ... | 1993 | 8105412 |
a search for the primary abnormality in adult-onset type ii citrullinemia. | deficiency of argininosuccinate synthetase (ass) causes citrullinemia in human beings. type ii citrullinemia is found in most patients with adult-onset citrullinemia in japan, and ass deficiency is found specifically in the liver. previous studies have shown that the decrease of hepatic ass activity is caused by a decrease in enzyme protein with normal kinetic properties and that there were no apparent abnormalities in the amount, translational activity, and gross structure of hepatic ass mrna. ... | 1993 | 8105687 |
haemagglutination-inhibiting antibodies against african horse sickness virus in domestic animals in nigeria. | a sero-epidemiological survey of african horse sickness (ahs) virus in 261 animals which included 96 camels, 81 horses, 80 dogs and 4 donkeys was carried out in nigeria. the animals had no history of vaccination against ahs. sera were tested by the haemagglutination-inhibition (hi) test for the presence of antibody against ahs virus. of these, 77 (95.1%) horse, 4 (100%) donkey, 10 (10.4%) camel and 28 (35%) dog sera samples tested were recorded as positive. the prevalence of antibody in samples ... | 1993 | 8111431 |
age related igg subclass concentrations in asthma. | the prevalence of igg subclass deficiency in asthma is still controversial. earlier studies often included patients receiving treatment with systemic steroids which can induce hypogammaglobulinaemia. concentrations of igg subclasses were studies in 200 children (aged 2-17 years) with asthma (mean asthma severity score (ass) 2, range 1-4) who had not received systemic steroids for at least six weeks before investigation, and in 226 healthy age matched controls. the mean concentrations of igg subc ... | 1994 | 8135559 |
nasal resistance in obstructive sleep apnea. | acute increases in nasal resistance are known to induce upper airway occlusion in predisposed subjects. with the limited efficacy of nasal surgery alone in the treatment of obstructive sleep apnea (osa), the relevance of chronically increased nasal resistance in the pathophysiologic features of osa remains undetermined. | 1994 | 8162738 |
epidemiological observations on sarcoids in a population of donkeys (equus asinus). | an epidemiological study of equine sarcoid in a population of 4126 donkeys showed that the peak incidence of the disease was 15.2 cases per 100 animal-years and occurred in animals in their fourth year of life. the crude incidence of the disease was 0.6 cases per 100 animal-years. the disease occurred most frequently in younger, male animals during their first five years in the population. the lesions were observed most commonly in the paragenital region. pre-entry quarantine procedures did not ... | 1994 | 8171807 |
detection of borna disease virus rna in naturally infected animals by a nested polymerase chain reaction. | borna disease virus in naturally infected horses, a donkey and sheep was detected for the first time by amplification of viral rna using pcr. in contrast to a control group of healthy horses, brain tissue was positive by this assay in all animals with neurological symptoms. the use of a second round of pcr with nested primers following southern hybridization confirmed the specificity and increased the sensitivity of the test. comparison with conventional methods recommends this technique for mon ... | 1994 | 8188810 |
generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene. | argininosuccinate synthetase (ass) is a urea cycle enzyme that forms argininosuccinate from citrulline and aspartate. mutations at the ass locus in man cause the inherited disease, citrullinemia. citrullinemia is inherited as an autosomal recessive trait and is characterized, biochemically, by elevated levels of blood citrulline and ammonia and often results in early neonatal death if untreated. we have used homologous recombination in embryonic stem cells to generate a line of mice having a tar ... | 1994 | 8197477 |
morphology of adult white donkeys of asinara. | the phenotype of the asinara white donkey has the following somatic characteristics: white coat, pink skin and glabrous areas, straight profile, body not very rounded on account of relatively slight muscular development, large head, eyes with irises of a pink-blue colour, short thin neck, not very pronounced withers, straight, average length dorsolumbar region, prominent angular rump higher than the withers, short chest, wide hind quarters, well developed abdomen, short sturdy limbs, light-colou ... | 1993 | 8198800 |
microsatellite analysis of loss of heterozygosity on chromosomes 9q, 11p and 17p in medulloblastomas. | medulloblastoma (mb) is a primitive neuroectodermal tumour of the cerebellum whose pathogenesis is poorly understood. previous studies suggest a role for loci on chromosomes 11p and 17p in the pathogenesis of mb. evidence for another potential mb locus has recently emerged from studies on gorlin syndrome (gs), an autosomal dominant syndrome with multiple basal cell carcinomas, epithelial jaw cysts, and skeletal anomalies. since gs can be associated with mb, we examined sporadic (non-gs) cases of ... | 1994 | 8208343 |
field observations in israel on hypersensitivity in cattle, sheep and donkeys caused by culicoides. | hypersensitive lesions in the skin of sheep, cattle and donkeys from various regions in israel are described. no cause other than insect bites was found. the animals were free of ticks, lice, fleas and blackflies, and of all the prevailing insect groups; culicoides spp were considered as the most probable cause of the hypersensitivity. lesions on the legs and abdomen were attributed mainly to c obsoletus meigen, c schultzel gp and c puncticollis becker, and less to c imicola kieffer. lesions on ... | 1993 | 8240175 |
stomach parasites of donkeys in morocco: habitat and interspecific interactions. | one hundred and four donkeys originating from several regions of morocco were necropsied during 1 year. the parasites in their stomachs were counted and locations determined in the cardiac, fundic and pyloric portions. synergistic or antagonistic interactions between parasites were assessed by a principal component analysis. gasterophilus intestinalis was only found in the cardiac portion and g. nasalis was mostly found in the pyloric portion. habronema were principally encountered in the pylori ... | 1993 | 8249256 |
[parasitological fecal studies of equids, dogs, cats and hedgehogs during the years 1984-1991]. | the results of the coproscopical examinations in horses, dogs, cats and hedgehogs between 1984 and 1991 are presented. in 9192 samples from horses 55.5% stages of strongylids, 4.0% of parascaris equorum, 2.2% of anoplocephalids, 1.6% strongyloides westeri, 0.7% of oxyuris equi, 0.6% of eimeria leuckarti, 0.2% of fasciola hepatica and 0.04% of dictyocaulus arnfieldi were found. in 48.0% of the 46 samples from donkeys eggs from strongylids were detected, in 17.4% larvae from dictyocaulus arnfieldi ... | 1993 | 8261912 |
pig leukocyte cysteine proteinase inhibitor (plcpi), a new member of the stefin family. | a new stefin type low-m(r) cysteine proteinase inhibitor (plcpi) was isolated from pig polymorphonuclear leukocytes as a contaminant of the cathelin sample. the inhibitor consists of 103 amino acids, and its m(r) was calculated to be 11,768. the inhibitor exhibits considerable sequence identity with inhibitors from the stefin family, particularly with human stefin a. the plcpi is a fast acting inhibitor of papain and cathepsins l and s (k(ass) > or = 1 x 10(6) m-1 x s-1) and forms very tight com ... | 1993 | 8262248 |
tamm-horsfall glycoprotein binds igg with high affinity. | tamm-horsfall protein (thp), a monomeric glycoprotein (m(r) 80 to 100 kda), is produced by the mammalian kidney's thick ascending limb of henle cells and excreted into the urine. the function of thp is uncertain. here we report that a high molecular weight contaminant in sheep thp (sthp) preparations was identified as sheep igg by its positive reaction with donkey anti-sheep igg antibody and with protein g. to answer the question of whether sthp and sheep igg co-purified because of a physical in ... | 1993 | 8264130 |
virucidal activity of an activated sludge supernatant. | the virucidal activity of the activated sludge aqueous phase was studied from the time of initial inoculation with a poliovirus type 1 suspension and for durations of three and nine days. the mixtures were incubated in presence of a nutritive medium at 26 degrees c and samples were drawn at regular intervals of time for viral titration. the activated sludge supernatant (ass) caused an important decrease of the titer of the poliovirus type 1 suspension especially after nine days of incubation. th ... | 1993 | 8267834 |
rapid evolution of horse satellite dna. | the major satellite of the horse genome consists of about 1 million copies of a 221-bp tandem repeat unit. by fluorescence in situ hybridization it has been localized in the centromeres of 58 of the 64 horse chromosomes. the donkey genome contains a similar but not identical satellite. strikingly, the equine repeat did not hybridize to dna of the grevy zebra, despite the divergence of the horse and zebra only 3 to 5 million years ago and the ability of these species to crossbreed. the evolution ... | 1993 | 8276394 |
purification and quantitative measurement of bovine serum amyloid-a. | bovine serum amyloid-a (b-saa) was purified from a pool of acute phase serum using hydrophobic interaction chromatography and gel filtration. serum was applied at a low salt concentration to a phenyl-sepharose column and saa was eluted with a gradient of 0 to 6 m guanidine-hcl. fractions containing saa were pooled, concentrated and further purified by gel filtration on superose-12. the concentration of saa in bovine serum was quantified by an indirect elisa using rabbit anti-human saa and horser ... | 1993 | 8284495 |
[the immunogenic properties of a recombinant vaccinia virus with an incorporated dna copy of the 26s rna of the venezuelan equine encephalomyelitis virus]. | a recombinant strain of vaccinia virus (vr26) containing a dna-copy of the subgenomic 26s rna of venezuelan equine encephalomyelitis virus (vee) inserted into the coding region of thymidine kinase (tk) gene was produced. this subgenomic rna contained the genes for all structural proteins of the vee virus, the strain trinidad donkey (trd). vr26 effectively expressed vee virus glycoproteins on the membranes of the infected cells. blood sera of vr26-immunized animals were found to contain vee virus ... | 1993 | 8284922 |
sympathetic denervation of the epicardial border zone in the genesis of dispersion of refractoriness and arrhythmogenesis in a 7-day-old canine myocardial infarction model. | the purpose of this study was to clarify whether sympathetic denervation occurs in the infarcted heart and contributes to the dispersion of the effective refractory period (erp) and arrhythmogenesis. | 1993 | 8287211 |
linkage analysis of infantile pyloric stenosis and markers from chromosome 9q11-q33: no evidence for a major gene in this candidate region. | a genetic component in the aetiology of infantile pyloric stenosis (ps) is well established. segregation analysis is compatible with a multifactorial sex modified threshold model of inheritance but a major gene of low penetrance has not been excluded. ps has been reported to occur in 57% (four of seven) of cases with duplication of chromosome 9q11-q33. twenty families with ps were studied using genetic markers at loci d9s55, d9s111, d9s15, d9s12, d9s56, d9s59, and ass from this region of chromos ... | 1993 | 8320701 |
[study on determination of gentamycin by enhanced chemiluminescent immunoassay]. | gentamycin was determined by solid antigen competition inhibition method of chemiluminescet immunoassay, in which luminol-(p-hydroxydiphenyl)-h2o2 was used a the chemiluminescence system and p-hydroxydiphenyl as the chemiluminescent enhancer. solid antigen was synthesized by a method in which gentamycin was immobilized covalently on microcrystalline cellulose previously activated by 1,1'-carbonyldiimidazole. the rabbit anti-gentamycin igg and the hrp-donkey anti-rabbit igg were used as the first ... | 1993 | 8340080 |
linkage analysis with chromosome 9 markers in hereditary essential tremor. | hereditary essential tremor (et) is an autosomal dominant disorder with variable expression and reduced penetrance. a tremor indistinguishable from et may be observed in patients with autosomal dominant idiopathic torsion dystonia (itd), in which the disease locus has been mapped to 9q32-34 in some kindreds, tightly linked to the argininosuccinate synthetase (ass) locus. we performed linkage analysis in 15 families with et containing 60 definitely affected individuals, using dinucleotide repeat ... | 1993 | 8341306 |
effects of fetal genotype and uterine environment on placental development in equids. | measurement of the concentrations of equine chorionic gonadotrophin (ecg) in the serum of pregnant mares and jenny donkeys carrying normal intraspecies and hybrid interspecies pregnancies suggested that the production of this hormone may be influenced by parental gene imprinting. specifically, a differential expression of maternal and paternal genes may control the size and secretory activity of the structures that secrete ecg, the fetal endometrial cups. however, bisection of an interspecies mu ... | 1993 | 8345479 |
african horse sickness. | ahs is a noncontagious vector-borne disease of equidae caused by orbiviruses. species susceptibility in decreasing order is horses, mules, donkeys, and zebras. the main vectors of ahs are culicoides. the disease is endemic in sub-saharan africa, but epizootics have occurred outside of this area on several occasions. the most recent outbreaks outside of the endemic area were in spain, morocco, and portugal between 1987 and 1990. ahs causes mortality up to 95% and is classically divided into four ... | 1993 | 8358648 |
comparison of five tests for the serologic diagnosis of myiasis by gasterophilus spp. larvae (diptera: gasterophilidae) in horses and donkeys: a preliminary study. | sera from 41 horses and 159 donkeys, from twelve states of méxico, were tested to ascertain anti-gasterophilus circulating antibodies by double immunodiffusion (dd), counterimmunoelectrophoresis (cie), indirect haemagglutination (ih), thin layer immunoassay (tia) and diffusion-in-gel elisa (dig-elisa) methods using crude somatic antigen from third instar larvae of g. intestinalis (degeer). at necropsy, 33/41 horses and 24/159 donkeys were found to be parasitized by g. intestinalis and/or g. nasa ... | 1993 | 8369558 |
wesselsbron virus haemagglutination: studies with erythrocytes of various animal species at different ph and temperatures. | the haemagglutinating (ha) properties of the nigerian strain of wesselsbron virus have been investigated using erythrocytes from a wide range of animals. the results showed that wesselsbron virus possesses ha activity when extracted using the sucrose and acetone method. the erythrocytes of goose, horse, donkey, pig, cattle, sheep, goat, monkey, man, rabbit, rat, guinea pig and chicken were agglutinated by wesselsbron virus at different ph values (5.75-7.0) and temperatures of 4 degrees c, room ( ... | 1993 | 8380321 |
group-reactive elisas for detecting antibodies to african horsesickness and equine encephalosis viruses in horse, donkey, and zebra sera. | group-reactive enzyme-linked immunosorbent assays (elisas) were developed to selectively detect antibodies to african horsesickness virus (ahsv) and equine encephalosis virus (eev), 2 orbiviruses that infect equids. in indirect elisa, guinea pig antisera to all known ahsv or eev serotypes recognized immobilized ahsv serotype 3 or eev cascara, respectively. antisera from naturally infected animals did not cross-react with their respective heterologous viruses. the elisa was used in parallel with ... | 1993 | 8385502 |
characterization of serum lysosomal enzymatic activities. iii. effect of infectious influenza in egyptian equines. | an outbreak of infectious influenza was recognized in menofeia governorate in october 1989. eight naturally influenza infected as well as 8 healthy control horses, mules and donkeys were selected for collection of blood and sera separation to estimate four lysosomal enzymatic activities and to describe the clinical findings, which were fever, congested nasal, conjunctival membranes and cough. bronchopneumonia followed later with bilateral purulent nasal discharge as a complication in 2 donkeys. ... | 1993 | 8387424 |
[the role of the inositol phosphate cycle in the cardioprotective effect of adaptation to repeated stressors]. | as shown by previous studies, adaptation to short-term stress exposure developed the phenomenon of adaptive stabilization of structures (phass), including such as elevation in resistance to impairing effects of isolated animal hearts and the heart nuclear fraction of elements of the sarcoplasmic reticulum. studies of the role of inositol phosphate regulatory cycle in the development of the ass phenomenon showed that the inositol triphosphate-diacyl glycerol (itp-dag) step of regulation was activ ... | 1993 | 8390126 |
serological evidence of equine arteritis virus in donkeys in south africa. | this paper reports the first serological evidence of exposure of donkeys to equine arteritis virus. seven hundred and thirty-four serum samples collected between 1989 and 1992 from donkeys in different areas of south africa were examined for the presence of antibodies against this virus by a microneutralization test. seventeen percent of serum samples tested positive. the distribution of seropositive animals varied from none in the western cape province and the transvaal highveld to 30% in the n ... | 1993 | 8392682 |
dna of bovine papillomavirus type 1 and 2 in equine sarcoids: pcr detection and direct sequencing. | nucleotide sequences of bovine papillomavirus (bpv) dna amplified by the polymerase chain reaction (pcr) from samples of equine sarcoid skin tumours were determined. all naturally occurring sarcoids (n = 58 tumours from 32 horses and 2 donkeys) contained bpv-dna. all but 3 of the genome fragments belonged to the bpv type 1 strain (bpv-1); the remaining were bpv type 2. similar results were obtained with cutaneous bovine papillomas used as controls (n = 20). one of the horses, carrying 2 sarcoids ... | 1993 | 8394687 |
algorithms for detecting antibodies to hiv-1: results from a rural ugandan cohort. | to evaluate an algorithm using two enzyme immunoassays (eia) for anti-hiv-1 antibodies in a rural african population and to assess alternative simplified algorithms. | 1993 | 8397940 |
molecular evidence that epizootic venezuelan equine encephalitis (vee) i-ab viruses are not evolutionary derivatives of enzootic vee subtype i-e or ii viruses. | enzootic strains of venezuelan equine encephalitis (vee) virus occur in the united states (florida), mexico, central america and south america. epizootic vee first occurred in north and central america in a widespread outbreak between 1969 and 1972. to investigate the likelihood that this epizootic vee virus, identified as vee antigenic subtype i-ab, evolved from enzootic viruses extant in the region, we cloned and sequenced the 26s mrna region of the genomes of the florida vee subtype ii virus, ... | 1993 | 8445371 |
physical mapping within the tuberous sclerosis linkage group in region 9q32-q34. | pulsed-field gel electrophoresis and flow dot-blot analysis have been used to construct a physical map of the q32-q34 region of chromosome 9, where one of the loci responsible for tuberous sclerosis (tsc1) has been mapped by genetic linkage. five linked groups of markers have been defined by pulsed-field gel electrophoresis. the orientation of these groups and the order of markers within them were determined by hybridization to flow-sorted dot blots derived from a panel of cell lines of chromoso ... | 1993 | 8449490 |
[domestic animals and veterinary medicine in the old and new testaments of the bible and the apocrypha]. | referring to an 1865 edition of the bible, the article deals with domestic animals and veterinary matters in the sacred book of christianity, singling out donkey, camel, horse, sheep, goat, pig, dog and cat. comments on early aspects of animal welfare and food hygiene round off the picture. | 1993 | 8457188 |
estimating the bodyweight of donkeys. | 1993 | 8460461 |