Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| infection of peruvian aotus nancymai monkeys with different strains of plasmodium falciparum, p. vivax, and p. malariae. | aotus nancymai (karyotype i) monkeys from peru were studied for their susceptibility to infection with plasmodium falciparum, p. vivax, and p. malariae. three strains of p. falciparum (santa lucia from el salvador, indochina i/cdc from thailand, and uganda palo alto) were inoculated into 38 monkeys. the results indicated that this species of aotus monkey is highly susceptible to infection. the uganda palo alto and the santa lucia strain parasites appear to be the most useful for immunologic and ... | 1988 | 3288739 |
| control of malaria in "tropical-paradise" hideaways. | 1988 | 3288851 | |
| double malarial infections. | 1988 | 3289129 | |
| malaria. a city hospital experience. | we reviewed the charts of 24 patients with malaria seen at the queens hospital center, jamaica, ny, over the past five years. twenty-three patients were foreign citizens. eighteen patients were infected with plasmodium vivax and six with plasmodium falciparum. malaria was suspected on admission in 19 of the 23 hospitalized patients. five patients were admitted with unrelated diagnoses, and four of these experienced diagnostic delay. all diagnoses were confirmed with thin blood smears. twenty-one ... | 1988 | 3289521 |
| pharmacokinetics of chloroquine in thais: plasma and red-cell concentrations following an intravenous infusion to healthy subjects and patients with plasmodium vivax malaria. | 1. chloroquine diphosphate (15 mg base kg-1) was given by constant rate intravenous infusion to two groups of thai subjects. eleven were patients with malaria (10 with plasmodium vivax and one case with plasmodium malariae) and 10 were healthy normal volunteers. 2. plasma and packed red-cell concentrations of chloroquine, electrocardiographic intervals, arterial blood pressure and pulse were measured at frequent intervals. 3. peak plasma concentrations at the end of the infusion ranged from 979 ... | 1988 | 3289601 |
| [clinical study on the treatment of malaria with artemether and artesunate]. | 1988 | 3289785 | |
| [detection of antibodies to vivax-malaria by elisa using in vitro cultured erythrocytic plasmodium cynomolgi as antigen]. | 1988 | 3289786 | |
| [experience in the consolidation measures in the final stage of malaria eradication in daxin county, guangxi]. | 1988 | 3289789 | |
| boosting of transmission-blocking immunity during natural plasmodium vivax infections in humans depends upon frequent reinfection. | the infectivity to mosquitoes of 31 acute plasmodium vivax patients was measured by permitting mosquitoes to feed directly on the patients. the infectivity of these patients correlated closely with titers of antibodies in their serum as measured by indirect immunofluorescence against air-dried female gametes of p. vivax. infectivity by direct feeding was also closely parallel to the transmission-blocking activity of the sera of patients as measured by the suppression of infectivity of parasitize ... | 1988 | 3290109 |
| [malaria]. | 1988 | 3292296 | |
| glucose-6-phosphate dehydrogenase deficiency in thailand: the influence on the clinical presentation of malaria in male adult patients. | one hundred and ninety-two male malaria patients admitted to two different hospitals within 1 year, were studied. there were 74 malaria cases with glucose-6-phosphate dehydrogenase (g-6-pd) deficiency and 118 g-6-pd normal malaria cases, randomly selected as a control group. history of dark urine, and the presence of jaundice, haematocrit, total bilirubin and parasite count on day of admission were not significantly different comparing both groups. the number of observed complications did not di ... | 1988 | 3292788 |
| plasmodium vivax: in vitro growth and reinvasion in red blood cells of aotus nancymai. | plasmodium vivax was maintained in experimentally infected aotus nancymai. positive monkeys were used as donors for culture material. after leucocyte removal with two different methods, including the classic cf11 method and a commercially available filter, parasites were grown under continuous shaking conditions in standard rpmi 1640, containing 20% human ab + serum. when mature schizonts were present, artificially induced reticulocytes from monkeys pretreated with the hemolytic drug phenylhydra ... | 1988 | 3294025 |
| erythrocytic schizogony and invasion of plasmodium vivax in vitro. | 1988 | 3294199 | |
| degradation of plasmodial antigens by human neutrophil elastase. | human neutrophil elastase (hne) has been well-studied with respect to its role in pathologic states, but less is known about the physiologic functions of this important granulocyte enzyme. in the present study, we show that hne can degrade the major circumsporozoite protein of the infective (sporozoite) stage of plasmodium vivax malaria, and that this enzyme can also interfere with the cytoadherence of human e infected with plasmodium falciparum (strain k+ fmg-fcr3) (ie). cytoadherence reactions ... | 1988 | 3294293 |
| sporozoite-induced infections of the salvador i strain of plasmodium vivax in saimiri sciureus boliviensis monkeys. | twenty saimiri sciureus boliviensis monkeys from bolivia were inoculated intravenously with sporozoites of the salvador i strain of plasmodium vivax. all animals were splenectomized 7 days after inoculation. inoculation of 100,000 sporozoites resulted in prepatent periods averaging 16.6 days; all monkeys developed high-level parasitemias with an average maximum of 103,000 per mm3. inoculation of 10,000 sporozoites resulted in average prepatent periods of 19.4 days; one of the resulting infection ... | 1988 | 3294366 |
| ['flu' following a visit to the tropics, a pitfall]. | 1987 | 3295566 | |
| seven patients with relapses of plasmodium vivax or p. ovale despite primaquine treatment. | seven relapses of plasmodium vivax or plasmodium ovale despite standard treatment with primaquine (3.0 mg kg-1) daily for fourteen days are presented. the majority of patients came from areas outside the countries where resistance to primaquine is well known. the various possibilities of reasons for relapses are discussed. | 1987 | 3299660 |
| whole blood concentrations of chloroquine and desethylchloroquine during and after treatment of adult patients infected with plasmodium vivax, p. ovale or p. malariae. | whole blood concentrations of chloroquine and desethychloroquine were determined during and after chloroquine treatment of 15 adult patients infected with p. vivax, p. ovale or p. malariae. the median of chloroquine concentrations remained practically unchanged in samples drawn three hours after initiation of treatment and in samples drawn immediately before the next dose of chloroquine. concentrations of chloroquine remained above 1.0 mumol/litre for at least four days. the calculated sum of ch ... | 1986 | 3299893 |
| failure of malaria chemoprophylaxis with a proguanil-chloroquine combination in papua new guinea. | proguanil 200 mg daily and chloroquine base 300 mg weekly were used as prophylaxis for 120 british army soldiers from hong kong on a seven-week jungle exercise in the highly malarious sepik district of papua new guinea. compliance was rigidly enforced. four men developed falciparum malaria whilst in papua new guinea and one within a few days of returning to hong kong. after stopping chloroquine four weeks after returning to hong kong 11 cases of mixed vivax and falciparum malaria and three cases ... | 1986 | 3299896 |
| exercise provocation test for clinical malaria. | 1987 | 3301796 | |
| malaria in papua new guinea. implications for the british army. | malaria poses the greatest health threat to british soldiers engaged in jungle training in papua new guinea. this paper provides detailed epidemiological information gained following a visit to the papua new guinea malaria research unit in january 1986. | 1987 | 3302246 |
| epidemic malaria in the hyperendemic north fly region of western province, papua new guinea. | 1987 | 3303730 | |
| field evaluation of enzyme-linked immunosorbent assays for plasmodium falciparum and plasmodium vivax sporozoites in mosquitoes (diptera: culicidae) from papua new guinea. | 1987 | 3305949 | |
| [field application of the indirect fluorescent antibody test in malaria control]. | 1987 | 3308159 | |
| regulation of the immune response in plasmodium falciparum malaria: iv. t cell dependent production of immunoglobulin and anti-p. falciparum antibodies in vitro. | t cells from patients with acute plasmodium falciparum malaria were investigated for induction of immunoglobulin- or anti-malaria antibody secretion in vitro. stimulation of autologous t/b cell mixtures (2t:1b) with low concentrations of p. falciparum antigen and cultured for 12 days gave rise to a t-dependent igg secretion which was significantly elevated over that in medium controls. this was achieved with both a crude p. falciparum antigen and a partially purified preparation enriched in pf 1 ... | 1987 | 3308213 |
| plasmodium vivax: exoerythrocytic schizonts recognized by monoclonal antibodies against blood-stage schizonts. | exoerythrocytic parasites of plasmodium vivax grown in human hepatoma cells in vitro were probed with monoclonal antibodies raised against other stages of p. vivax. monoclonal antibodies specific for four independent antigens on blood-stage merozoites all reacted with exoerythrocytic schizonts and merozoites by immunostaining. the characteristic staining pattern of each monoclonal antibody was similar on both blood- and exoerythrocytic-stage parasites and appeared only in mature schizont segment ... | 1987 | 3308506 |
| chesson strain plasmodium vivax in saimiri sciureus boliviensis monkeys. | nine saimiri sciureus boliviensis monkeys were inoculated with sporozoites of plasmodium vivax (chesson strain) dissected from anopheles stephensi mosquitoes infected by feeding on blood from infected chimpanzees. the animals were splenectomized 7 days after inoculation. seven animals developed infections with prepatent periods ranging from 12 to 43 days (mean of 19.6 days). parasitemias were low during the first 50 days. maximum parasitemias in 5 animals in which the strain adapted ranged from ... | 1987 | 3309241 |
| [sero-epidemiologic study of malaria in puerto madero, chiapas, 1985]. | 1987 | 3310262 | |
| clinical evaluation of antimalarial regimens in japan. | the actual situation of the treatment of malaria for the past 10 years in japan was investigated and analyzed. as a result, it was revealed that there were not a few cases which had been treated improperly probably because of the difficulty of getting antimalarial agents. moreover, it was made clear that the death rate on falciparum malaria was constantly high, 8.7%, as expected and the relapse rate of vivax malaria was still as high as 18.0%. there was the recrudescence of falciparum malaria at ... | 1987 | 3310468 |
| development of plasmodium vivax in anopheles superpictus under experimental conditions. | the susceptibility of anopheles superpictus for plasmodium vivax was described quantitatively under laboratory conditions. of the 697 laboratory females studied in 16 groups, 513 (73.5%) females took a bloodmeal, of which 88.4% developed ookinetes on day 1, 56.1% oocysts between days 3 and 11, and 52.5% sporozoites in the salivary gland on days 15 to 63 post-infection. sporogony was completed in 10-11 days post-infection. there was no difference in the longevity of uninfected and infected female ... | 1987 | 3310681 |
| the efficiency of sporozoite transmission in the human malarias, plasmodium falciparum and p. vivax. | reported are malaria sporozoite and inoculation rates over a 1-year period in eight epidemiologically defined villages of different endemicity in madang province, papua new guinea. in the study, more than 41 000 wild-caught mosquitos were analysed for plasmodium falciparum and p. vivax sporozoites by elisa. in a given village the entomological inoculation rates correlated strongly with the prevalences of both these malarial parasites in children. however, the prevalence of p. falciparum infectio ... | 1987 | 3311441 |
| demonstration of antigenic polymorphism in plasmodium vivax malaria with a panel of 30 monoclonal antibodies. | a panel of 30 monoclonal antibodies was established against asexual erythrocytic stages of plasmodium vivax and used to investigate the antigenic composition of the parasite. at least 38 different antigenic polypeptides of p. vivax were characterized by the western blot technique. the possible location of these antigens, as well as their stage and species specificity, was determined on the basis of the staining patterns produced by these antibodies on air-dried parasites in the indirect immunofl ... | 1987 | 3312003 |
| detection and quantification of plasmodium falciparum and p. vivax infections in thai-kampuchean anopheles (diptera: culicidae) by enzyme-linked immunosorbent assay. | 1987 | 3312607 | |
| some observations on sympatric populations of the malaria vectors anopheles leucosphyrus and anopheles balabacensis in a village-forest setting in south kalimantan. | human bait collections of biting anopheline mosquitoes were made on five consecutive nights during september 1986 in a remote village located in a heavily forested area of south kalimantan, indonesia. anopheles leucosphyrus and an. balabacensis comprised 97.7% of the total number of specimens collected outside houses in the village. anopheles balabacensis were slightly fewer in total numbers than leucosphyrus. mosquitoes were collected simultaneously in the village and the forest on two nights. ... | 1987 | 3313741 |
| [monoclonal antibodies against erythrocytic stages of plasmodium vivax: ig isotype determination and analysis of species and stage-specific immunofluorescein reactions]. | 1987 | 3315952 | |
| serological diagnostics of imported malaria in czechoslovakia. | two serologic techniques for malaria detection were compared in this study; the indirect fluorescent antibody (ifa) test used in 214 persons (38 czechoslovak citizens returning from visits to tropical countries and 176 foreign visitors arriving to czechoslovakia from areas endemic for malaria) and the indirect hemagglutination (iha) test employed in 125 persons (29 czechoslovak citizens and 96 foreigners). comparisons revealed poor correlation between the ifa test and iha test data. of the two t ... | 1987 | 3316380 |
| [value of the immune response in assessing the efficacy of an antimalarial treatment]. | 1987 | 3317691 | |
| a metropolitan hospital in a non-endemic area provides a sampling pool for epidemiological studies on vivax malaria in sri lanka. | an analysis of records of 494 malaria patients admitted to the general hospital in colombo (the capital of sri lanka where malaria transmission is not known to occur) from 1981 to 1984 is presented and compared with national malaria data from the entire country. the incidence of predominantly plasmodium vivax malaria rose sharply over the 3 years; its species distribution and seasonal variation in patients in the general hospital, colombo (ghc) generally reflected the disease pattern in the coun ... | 1987 | 3318015 |
| induced malaria and antibody titres in acute infections and in blood donors in kuwait. | concurrent with the increase in the number of imported cases of malaria into non-endemic kuwait during the past 5 years, induced infections have been identified for the first time. we report 10 such cases over a 4-year-period. of 8 transfusion-induced infections, 4 were due to plasmodium falciparum and 4 to p. vivax. the mean incubation period for p. falciparum patients was 13 d and for p. vivax, 17 d. an accidental syringe-needle transmission and a congenital infection were due to p. falciparum ... | 1987 | 3318016 |
| plasmodium vivax malaria from mexico--a problem in the united states. | 1987 | 3318139 | |
| [congenital malaria: a reality not to be overlooked. apropos of a case]. | 1987 | 3318635 | |
| cerebral malaria and mixed falciparum-vivax infections. | of the seventy cases of cerebral malaria seen at the duchess of kent hospital, sandakan between january 1984 and june 1986, 57 (81.4%) were due to plasmodia falciparum and 13 (18.6%) were due to mixed p. vivax--p. falciparum infections. mixed infection cerebral malaria was associated with a more severe anaemia and may carry a poorer prognosis. indigenous children under five years of age are particularly at risk of death from mixed infections. | 1987 | 3318659 |
| plasma concentrations and toxicity of chloroquine after slow intravenous infusion in patients with falciparum malaria. | five male patients with acute plasmodium falciparum or plasmodium vivax infections were infused with chloroquine diphosphate (15 mg kg-1) over four hours. further does of chloroquine diphosphate (5 mg kg-1) were given at 12, 24, 36 and 60 hours. plasma chloroquine concentrations were determined before and four hours after each dose and then daily until discharge. no serious cardiovascular toxicity was observed, and plasma chloroquine concentrations exceeding the putative minimum inhibitory conce ... | 1987 | 3318731 |
| induction of sporozoite-specific memory cells in mice immunized with a recombinant plasmodium vivax circumsporozoite protein. | a recombinant plasmodium vivax circumsporozoite (cs) protein (rpvcs-1) has been investigated as a possible malaria sporozoite vaccine candidate. experiments were carried out to determine whether sporozoite-specific memory cells develop in swiss webster mice immunized with rpvcs-1. challenge of rpvcs-1-immunized mice with p. vivax sporozoites resulted in a 100-fold increase in the mean serum anti-sporozoite antibody titer. the presence of parasite-specific t helper cells was demonstrated using an ... | 1987 | 3319650 |
| value of immunofluorescent assay (ifa) in serodiagnosis of malaria. | 1987 | 3320220 | |
| quinine in health care in the tropics. | 1987 | 3321836 | |
| reduced erythrocyte survival following clearance of malarial parasitaemia in thai patients. | erythrocyte survival times were measured in healthy thai controls and in patients following clearance of asexual p. falciparum or p. vivax parasitaemia. in five controls the mean cell life (mcl) of compatible donor erythrocytes was 89.6 d (mean range 73-101 d) compared with a mean mcl of 56.8 d (range 30-66 d) for autologous erythrocytes in 12 falciparum patients. in one of these patients the survival curve was biphasic with a rapid loss of some labelled cells. the survival of compatible donor e ... | 1987 | 3322362 |
| congenital malaria (a report of 2 cases). | 1987 | 3323475 | |
| malaria in foreign visitors to britain. | malaria cases reported in britain are increasing. foreign visitors ill with malaria while visiting britain form an important category. this paper reviews notifications to the malaria reference laboratory (m.r.l.) of cases of malaria in foreign visitors in 1985. there were 427 cases reported in this group which is nearly 20% of the total number reported. it was found that the foreign visitors had a higher proportion of plasmodium falciparum and that a third of the cases were aged 20-29 years. six ... | 1987 | 3323546 |
| neonatal malaria: a clinical study of congenital and transfusional malaria. | 1987 | 3323547 | |
| malaria in the malaysian army with particular reference to chemosuppressive use. | 1987 | 3323860 | |
| [epidemiological aspects of imported malaria 1976-1985]. | the comparative analysis of the cases of imported malaria in lombardy and in italy during the ten-years period 1976-1985 shows that the prevalent factors of risk are, in both case-lists, the young age, the work motivated travelling and the stay in endemic areas of tropical africa, where p. falciparum is greatly prevalent. interesting outcomes of comparison of the two consecutive five-years periods 1976-1980 and 1981-1985 are discussed. as far as the african provenience (decreased) and the work m ... | 1987 | 3325074 |
| comparison between autoantibodies in malaria and leprosy with lupus. | sera from 16 patients with falciparum malaria, 16 patients with vivax malaria and 31 patients with leprosy were tested for autoantibodies to intracellular proteins and nucleic acids. precipitating antibodies to soluble protein extracts were not detected in any serum. sera from malaria patients showed prominent immunofluorescence staining of the hep2 nuclear membrane as well as frequent 75% (24/32) and intense western blot reactivity. in contrast, only 20% and 36% of patients with leprosy had pos ... | 1987 | 3325202 |
| detection of plasmodium vivax in human blood using synthetic dna probe. | 1987 | 3326754 | |
| plasmodium vivax: isolation of mature asexual stages and gametocytes from infected human blood by colloidal silica (percoll) gradient centrifugation. | the densities of human erythrocytes infected with p. vivax obtained from infected patients were determined by isopycnic centrifugation in continuous gradients of percoll. the approximate densities of erythrocytes infected with rings were 1.086 to 1.1, trophozoites (amoeboid stages) 1.053 to 1.086, schizonts and gametocytes 1.053 to 1.056 and of the other cellular elements of blood, uninfected erythrocytes, 1.086 to 1.1, polymorphonuclear leucocytes 1.073 to 1.086 and mononuclear cells 1.062 to 1 ... | 1987 | 3328333 |
| endemic malaria in four villages of the pakistani province of punjab. | the prevalence of malaria in 4 villages 60 km south of lahore, punjab, where anopheles culicifacies is the vector was estimated from blood films made during three mass malaria surveys (ms) and at 204 clinics (cs) held over 18 consecutive months. the highest parasite rate occurred during october 1984 when 43% of the cs population had parasitaemias. plasmodium vivax predominated early in the major transmission season (23% and 15% vivax parasitaemias in august 1983 and 1984 respectively) whereas p. ... | 1987 | 3328334 |
| reduction in erythrocytic gsh level and stability in plasmodium vivax malaria. | the existence of haemolytic anaemia in malaria indicates disturbances in red cell stability due to physical as well as metabolic stress attributable to the malarial parasite. as erythrocytic reduced glutathione (gsh) is involved in maintaining the integrity of red cells, the status of erythrocytic gsh was studied in 40 patients infected with plasmodium vivax before and after therapy with chloroquine. 40 normal subjects, age- and sex-matched, were studied as controls. the level of erythrocytic gs ... | 1987 | 3328336 |
| [a preliminary study on the infectivity of different geographic strains of plasmodium vivax to anopheles sinensis]. | 1987 | 3329066 | |
| [studies on control measures of vivax malaria in juye county, shandong province]. | 1987 | 3329068 | |
| [a study on the theoretical distribution of the long-incubation tertian malaria in a period of one year]. | 1987 | 3329571 | |
| malaria presenting as purpura. | 1987 | 3329650 | |
| hereditary ovalocytosis and reduced susceptibility to malaria in papua new guinea. | ovalocytosis, an hereditary condition in which most erythrocytes are oval in shape, is a polymorphism that occurs in up to 20% or more of the population in papua new guinea and malaysia. due to the geographical correlation of the trait with endemic malaria, the possibility of a selective advantage in resistance to malaria has been raised. in a study of 202 individuals with greater than or equal to 50% oval red cells matched by age, sex and village of residence with controls having less than or e ... | 1987 | 3329776 |
| the haematocrit centrifuge smear technique for the detection of mammalian plasmodium. | 1987 | 3329782 | |
| [a study of monoclonal antibody elisa test to detect malaria parasite antigens]. | 1987 | 3329991 | |
| [scanning electron microscopic study on the late stage of sporogony of plasmodium vivax]. | 1987 | 3329992 | |
| [pharmacokinetics of pyronaridine in malaria patients]. | 1987 | 3330403 | |
| specific igm and igg antimalarial antibody responses in paired samples from malaria patients. | 1987 | 3330713 | |
| studies on the development of plasmodium vivax in anopheles subpictus. | 1987 | 3330714 | |
| studies on the detection of malaria at primary health centres. part iii. parasitological profile of population surveyed for malaria through passive case detection. | 1987 | 3330715 | |
| [respiratory manifestations in plasmodium falciparum and vivax malaria]. | 1987 | 3331486 | |
| diagnosis of tertian malaria by enzyme-linked immunosorbent assay. | a method of elisa diagnosis of tertian malaria based on detecting plasmodium vivax antigen in red blood cells (rbc) was developed, using 0.16 ml of packed, washed, and sonicated rbc. 68 blood samples from tertian malaria cases were examined; 67 (98.5%) were positive. 104 normal persons were all negative by this test. the lowest parasite number detected was 3 parasites/10(5) rbc on a thin film, or 1-2 parasites per thick film of usual size. | 1987 | 3332504 |
| some entomological observations on malaria transmission in a remote village in northwestern thailand. | anopheline mosquitoes and their relation to malaria transmission were studied during the months of march, may and july in the karen village of mae tha waw located in the northwestern mountains of tak province. thirteen species were captured on human bait during 80 man-nights of collecting. four additional species were collected during routine larval surveys. anopheles minimus and an. maculatus comprised 92.5% of the specimens captured biting man. anopheles minimus and an. nivipes were implicated ... | 1987 | 3333058 |
| newly incriminated anopheline vectors of human malaria parasites in junin department, peru. | sporozoite data from salivary gland dissections are presented that clearly incriminate anopheles trinkae, an. pseudopunctipennis, an. sp. near fluminensis, an. oswaldoi, an. nuneztovari and an. rangeli as vectors of malaria parasites in the rio ene valley, a hyperendemic malarious area in junin department, eastern peru. anopheles trinkae is considered the most important vector based on dissections, abundance and man-vector contact. other notes are presented on the relative abundance, bionomics a ... | 1987 | 3333060 |
| first record of malaria and associated anopheles in el gara oasis, egypt. | 1986 | 3333789 | |
| anopheles population dynamics in two malaria endemic villages in faiyum governorate, egypt. | anopheles populations were monitored for one year in 2 neighboring villages in faiyum governorate, egypt, to study factors causing differences in malaria prevalence. both villages contained the following species: anopheles pharoensis, an. sergentii, an. multicolor and an. tenebrosus. abundant larval breeding sites in abheet, the village with the higher malaria rate, accounted for the higher adult densities observed from human and animal biting collections and from indoor resting collections. ano ... | 1986 | 3333790 |
| [epidemiologic information on malaria in the state of são paulo, brazil]. | 1987 | 3333874 | |
| changes in the geographical distribution of malaria throughout history. | climatic changes must have greatly affected the distribution of malaria in prehistoric times. paleobotanical evidence, snowline depression studies and information obtained from deep sea sediment cores, indicate that southern europe must have suffered a drop of summer temperatures of approximately 9 degrees c during the last glacial maximum, 18,000 years ago. such a drop would have been decisive as regards the distribution of malaria and its vectors. if present at all, the disease would have been ... | 1987 | 3334082 |
| the dutch school of malaria research. | an epidemic of tertian malaria in some coastal areas of the netherlands resulted in the setting up of official measures in 1920. a scientific and a propaganda commission were charged with control. efforts were made to reduce mosquito populations by adult and larval spraying. after the discovery that infected mosquitoes were to be found only inside houses, control operations were focussed against adult mosquitoes. some later discoveries resulted in a more effective control. a) spraying ditches wi ... | 1987 | 3334084 |
| rapid and sensitive quantitative analysis of the new antimalarial n4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8- quinolinyl]-1,4-pentanediamine in plasma by liquid chromatography and electrochemical detection. | a rapid, sensitive and simple method was developed for the quantitation of the plasma concentration of n4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8- quinolinyl]-1,4-pentanediamine, a new antimalarial active against plasmodium vivax. n4-(5-hexoxy-6-methoxy-4-methyl-8-quinolinyl)-1,4- pentanediamine diphosphate, a similar 8-aminoquinoline, was used as an internal standard. the method involves sample clean-up by a prepacked cyano solid-phase column followed by reversed-phase liquid c ... | 1988 | 3372627 |
| antibodies to htlv-iii/lav in venezuelan patients with acute malarial infections. | 1986 | 3511375 | |
| the epidemiology of malaria in a population surrounding madang, papua new guinea. | malaria is prevalent throughout coastal and lowland papua new guinea. recent changes, including a shift from predominance of plasmodium vivax to plasmodium falciparum, appearance of chloroquine-resistant p. falciparum and decreased effectiveness of vector control programs have been observed. epidemiological features of malaria were studied through four six-month surveys of a population of 16,500 in madang province from 1981-1983. baseline data on parasitology, splenic enlargement, serology, hemo ... | 1986 | 3511748 |
| infection of mosquitoes with plasmodium vivax from chimpanzees using membrane feeding. | six splenectomized chimpanzees were infected with the chesson or the north korean strains of plasmodium vivax. heparinized blood taken from the animals was fed to approximately 45,000 mosquitoes using parafilm membranes. high-level mosquito infections were obtained with the blood from 4 animals. one animal infected mosquitoes only at a very low level. the other chimpanzee failed to produce a parasitemia high enough to warrant mosquito feeding. | 1986 | 3511751 |
| effects of fansidar on chloroquine-resistant plasmodium falciparum in pakistan. | fansidar (sp), a combination of sulfadoxine and pyrimethamine, was evaluated for its usefulness as a curative agent for treating individual malaria patients and for reducing the community reservoir of plasmodium falciparum in 4 villages near lahore, pakistan, where resistance of 4-aminoquinolines has recently been reported. following the end of the major malaria transmission season, we carried out a month-long mass treatment campaign during which sp was given to all available villagers who had p ... | 1986 | 3511752 |
| vivax malaria. | malaria occurs in the united states infrequently and is found exclusively among immigrants and travelers returning from areas where the disease is endemic. cases of acute relapses of plasmodium vivax infection can present to the emergency department. patients are often immigrants from developing countries who were symptom-free in this country for weeks or months preceding their illness. the clinical presentation and current treatment of malaria are reviewed. malarial infection may become apparen ... | 1986 | 3511922 |
| genetic markers and malaria. observations in gujarat, india. | 189 healthy controls and 175 patients suffering from malaria vivax have been investigated with regard to associations between this disease and 22 genetic polymorphisms of the blood (abo, mn, ss, rh, kell, p, lutheran, kidd, duffy, diego, xg; abh-secretor; hp, gc, gm, km; ap, ak, pgm1, 6-pgd, esd; hb variants) significant associations could be demonstrated only for p and hp systems, though in accordance with other investigations it cannot be excluded that the abo system plays also a role in this ... | 1986 | 3512422 |
| specific dna probe for the diagnosis of plasmodium falciparum malaria. | malaria can be diagnosed either by direct microscopic examination of blood smears, which is time consuming and requires expertise, or by immunological techniques, which are effective but do not distinguish between past and present infections. in this study, a simple procedure was developed for spotting lysed blood from infected patients directly onto nitrocellulose paper and identifying the malaria species on the basis of hybridization of parasite dna with a species-specific probe. a genomic dna ... | 1986 | 3513309 |
| field trial in chiapas, mexico, of a rapid detection method for malaria in anopheline vectors with low infection rates. | a method consisting of filtration of up to 100 macerated mosquitoes in a batch, followed by fixation with glutaraldehyde and concentration of filtrate by centrifugation has been developed to rapidly assess malaria infection in anopheline mosquitoes. determination of the presence of sporozoites is made by observation of a sample of the final filtrate with a phase microscope. the method is simple and field adaptable, essential factors for the application of any technique to large scale field opera ... | 1986 | 3513640 |
| treatment of falciparum malaria with quinne and tetracycline or combined mefloquine/sulfadoxine/pyrimethamine on the thai-kampuchean border. | three different regimens were compared for treatment of falciparum malaria in displaced kampucheans living in encampments on the thai-kampuchean border in 1983: single dose 750 mg mefloquine, 1.5 g sulfadoxine, 75 mg pyrimethamine (msp); 600 mg quinine 8-hourly for 3 days and 500 mg tetracycline 8-hourly for 7 days (q3t7); or 600 mg quinine 8-hourly for 7 days and 500 mg tetracycline 8-hourly for 7 days (q7t7). radical cure rates were 98% (40/41) for msp, 76% (32/42) for q3t7 and 92% (33/36) for ... | 1986 | 3513642 |
| detection of antibodies to plasmodium vivax by indirect immunofluorescence: influence of the geographic origin of antigens and serum samples. | the results of a double-blind serological study of 15 sera sampled in a residual focus of vivax malaria transmission in algeria, and of 7 sera from patients with slide-proven p. vivax infections acquired in india, are analyzed. the reactivity of each of these serum samples was tested by indirect immunofluorescence using 6 different batches of antigen, including 3 batches of p. vivax antigen prepared with isolates from zaire (africa), india and the solomon islands, respectively. the geometric mea ... | 1986 | 3513643 |
| observations on early and late post-sporozoite tissue stages in primate malaria. iv. pre-erythrocytic schizonts and/or hypnozoites of chesson and north korean strains of plasmodium vivax in the chimpanzee. | in a continuing reexamination of plasmodial tissue stages within the context of the hypnozoite theory of malarial relapse, 2 strains of plasmodium vivax with distinct and disparate relapse characteristics in humans were studied in chimpanzees. following intravenous inoculation of massive numbers of salivary gland sporozoites, both the frequently relapsing chesson strain and a north korean strain characterized by predominantly delayed relapses exhibited relapse patterns and antimalarial sensitivi ... | 1986 | 3513645 |
| blood parasites: problems in diagnosis using automated differential instrumentation. | to examine potential problems inherent in using automated differential instruments, we have reviewed herein two cases where blood parasites, plasmodium vivax and plasmodium falciparum, were completely missed by use of this method. diagnosis of these infections was made when blood was sent to the parasitology laboratory after having been missed prior to that time. the first problem involved the laboratory request slip; no indication was made concerning possible suspect organisms. therefore, perip ... | 1986 | 3514101 |
| congenital malaria in scandinavia. | a case of plasmodium vivax malaria in a 3-week-old infant, born in norway of a pakistanian mother, is reported. the child was admitted with a febrile illness of unknown origin, persistent vomiting, reduced body weight, thrombocytopenia, elevated total level of igm, and a slightly positive specific igg antibody titer. the mother had malaria during the puerperium, and febrile episodes 6-8 weeks before parturition. this is the first case of congenital malaria reported from scandinavia. | 1986 | 3515510 |
| role of plasmodium vivax in oxidation of haemoglobin in red cells of the host. | 1986 | 3516868 | |
| polyresistant malaria in gurkha soldiers returning from papua new guinea: treatment and prevention. | two company strength exercises to papua new guinea produced 21 malaria casualties of whom 16 had potentially fatal falciparum infections. the chemotherapy and prevention of polyresistant malaria from papua new guinea and the threat posed to the hong kong environment regarding malaria re-introduction are discussed. | 1986 | 3517314 |
| [the pharmacology of antimalarials]. | 1986 | 3518010 | |
| [malaria despite chemoprophylaxis: problems for diagnosis and therapy]. | 1986 | 3518011 | |
| [current recommendations for malaria prevention]. | 1986 | 3518012 | |
| falciparum malaria--210 cases. | 1986 | 3519571 | |
| neonatal malaria and obstructive jaundice. | a case is presented of transplacental malaria in an infant associated with persistent conjugated hyperbilirubinaemia and liver disease. | 1986 | 3521497 |
| [malaria vaccine research]. | in 1976 "the immunology of malaria scientific working group" was established. the target of the organization was to study especially p. falciparum and other malaria strains antigens and then prepare a suitable vaccine against them. they carried out many experiments until the end of 1985, when they made the remarkable discovery by isolating the p. falciparum sporozoite surface antigen and named it "the circumsporozoite" (cs) protein. therefore they are hopeful to prepare a sporozoite vaccine in t ... | 1986 | 3523172 |