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aspergillus fumigatus and lung disease.the range of clinical presentations of lung diseases associated with aspergillus spp. is great. the conditions are very frequently misdiagnosed but errors should be avoided if the possibility of a fungal cause is considered and simple immunological tests undertaken. often no more than skin-prick tests and serum precipitins need to be done. in many cases, fungus is not isolated from the sputum and negative results do not exclude the possibility of a. fumigatus as the causal agent. treatment often ...1979392479
exposure of rabbits to spores of aspergillus fumigatus or penicillium sp: survival of fungi and microscopic changes in the respiratory and gastrointestinal tracts.rabbits were exposed to spores of aspergillus fumigatus by 1 of 2 routes: exposure to aerosols of dry spores or introduction of liquid suspensions of spores directly into the stomach. rabbits also were exposed to aerosols containing spores of a penicillium sp. cultural and microscopic examinations of tissues from the respiratory and gastrointestinal tracts indicated fungi were distributed throughout the gastrointestinal tract of the rabbits within 1 hour after exposure to aerosols of a fumigatus ...1979393142
betaine-homocysteine methyltransferase in the fungus aspergillus nidulans. 1979393259
the effect of ultrasound on genetic instability in diploids of aspergillus nidulans.ultrasonication at 20 khz and intensity of 59 w/cm2 of a diploid strain of aspergillus nidulans was ound to lead to a significant increase in haploidization of germinating conidiospores. in a preliminary study ultrasound was found not to have an effect on the rate of reverse mutation in conidiospore suspensions of auxotrophic mutants.1979393595
thermophilic and thermotolerant fungi in poultry droppings in nigeria.ten species of fungi were obtained from poultry droppings in nigeria. six of these are true thermophiles while the other four are thermotolerant. aspergillus fumigatus fresenius, mucor pusillus lindt and thermoascus aurantiacus stolk are known human pathogens. except for m. pusillus, all the thermotolerant species had a higher occurrence at 45 degrees c while the thermophilic varieties were readily obtained at 50 degrees c.1979393797
allele specific and locus non-specific suppressors in aspergillus nidulans.using n-methyl-n'-nitro-n-nitrosoguanidine, ultraviolet irradiation, ethyl methanesulphonate or 4-nitroquinoline-1-oxide mutagenesis and an enrichment method for the isolation of auxotrophs, 25 mutants with defects in the ada locus were obtained after screening 41,376 colonies. one of these, ada24, did not complement with any of the other ada mutants, had a very high reversion rate and had some other properties which usually characterize strains carrying nonsense mutations. all revertants of ada ...1979393802
[enzymolysis of the acidic hydrolysates of plant residues]. 1979393967
haemoptysis in eosinophilic granuloma.eosinophilic granuloma of bone may involve the lung in about 20% of cases (lewis 1964); and may present in the lung without other organ involvement. haemoptysis occurs in about 10% of cases for unknown reasons. i document here a case with typical presentation and course, but which was complicated by haemoptysis of increasing severity leading to death. the cause of haemoptysis was diagnosed at fibreoptic bronchoscopy.1979394756
detection of 5-amino-4-imidazole-n-succinocarboxamide ribotide and hypoxanthine accumulation. a simple method for identification of some purine auxotrophs. 1979395166
allele specific, gene unspecific suppressors in aspergillus nidulans.seven suppressor mutations have been isolated in aspergillus nidulans by coreversion of alleles in physiologically unrelated genes namely, alx, sb, alca, putative structural genes for allantoinase, sulphate permease and alcohol dehydrogenase respectively. the suppressors are allele specific, gene unspecific. those described map in four loci, suaa, b, c, d. suaa and suab are on linkage group iii, suac and suad on vii. suab111, suad103 and suad108 are semi-dominant in their suppression of alx4 and ...1979395416
endogenous fungus endophthalmitis (probably aspergillus).a 53-year-old organic chemist developed severe asthma and bronchitis a few weeks after professional exposure to plant dust. 15 days later an acute severe endophthalmitis occurred. both the systemic and eye conditions were treated with corticosteroids and antibiotics. the atrophic eye which was enucleated 6 months later histologically revealed abscesses in the iris, ciliary body, lens and vitreous harbouring numerous islands of septate, dichotomously branching hyphae, orientated in the same direc ...1979395478
[results of local treatment of pleural aspergillosis]. 1979395511
[aspergillus endocariditis on a cardiac valve prosthesis. a problem to be solved]. 1979395608
isolation of some new tryptoquivaline-related metabolites from aspergillus fumigatus. 1979396046
bacteriological mycological and parasitological study in childhood diarrhoeas in bikaner (western rajasthan). 1979396251
phenotypes of double conidiation mutants of aspergillus nidulans.a series of strains, doubly mutant at conidiation loci, have been made. the phenotypes of these strains reflected the epistasy of earlier blocking mutants over later ones and confirmed the order of gene sequence predicted from the phenotypes of single mutants. oligosporogenous mutants gave complex interactions, especially between brl and med mutants. these results indicated that (i) gene action overlapped in time, (ii) several parts of the conidial apparatus were interchangeable and (iii) nuclei ...1979396353
evidence that p-fluorophenylalanine has a direct effect on tubulin in aspergillus nidulans.three temperature-sensitive alleles of bena (bena11, 17 and 21) confer resistance to growth inhibition by p-fluorophenylalanine (fpa). fpa resistance cosegregates with the bena gene. two back-mutations in bena which cause loss of temperature sensitivity cause loss of fpa resistance, and two indirect suppressors of bena temperature sensitivity also cause fpa resistance to be lost. these results indicate that fpa resistance is an intrinsic property of the bena mutations. the intracellular phenylal ...1979396355
investigation of the hemolytic site of asp-hemolysin. 1979396392
the effect of beta-glucuronidase and chitinase on the cell wall of aspergillus niger and aspergillus fumigatus.the effects of beta-glucuronidase and chitinase have been tested on the hydrolysis of the cell walls of the economically important fungi, aspergillus niger and aspergillus fumigatus. the extent of wall hydrolysis was measured by assaying for total reducing sugars, n-acetyl sugars and protoplast production. maximum reducing sugar release was attained after 40 min incubation, both with beta-glucuronidase supplemented with chitinase and beta-glucuronidase alone, whereas n-acetyl sugar release reach ...1979396451
a guide to the recent literature on aspergillosis as caused by aspergillus fumigatus, a fungus frequently found in self-heating organic matter.spores of aspergillus fumigatus have been found to be abundantly present in the outdoor air at a site where large scale experimental composting of sewage sludge is in progress at beltsville, maryland. the health significance of this finding, for that site and for others in the future, is still only incompletely understood. further studies are in progress to characterize absolute concentrations of the spores of the fungus in air at the site, spore dispersal by air from composting operations, and ...1979396477
[pulmonary atelectasis caused by bronchocentric aspergillosis: an other farmer's pneumoconiosis]. 1979396705
mutagenicity of 5,6-dimethoxysterigmatocystin, a metabolite from aspergillus multicolor, in the salmonella/microsome system.the natural sterigmatocystin derivative, 5,6-dimethoxysterigmatocystin, was found to be a mutagen for salmonella typhimurium strains ta98 and ta100 after metabolic activation in a mammalian microsome system.1979396882
germination of non-irradiated and gamma-irradiated fungal spores on water agar and natural soil.germination and germ-tube lengths of non-irradiated and gamma-irradiated spores of eight soil fungi were studied on water agar and on natural soil. non-irradiated spores showed variable degrees of sensitivity to the fungistatic factor in natural soil. lower doses of gamma-irradiation (5 k rad) produced stimulus to germination and germ-tube lengths without losing the fungistatic properties of the fungi concerned. germination at the rest of treatments (100 and 500 k rad) showed significant inhibit ...1979396932
toxicity and mutagenicity of molds of the aspergillus glaucus group. identification of physcion and three related anthraquinones as main toxic constituents from aspergillus chevalieri. 1979397244
[animal experiments on the pharmacokinetics of ocrase (author's transl)].the blood level, distribution and elimination of ocrase, a protease from aspergillus ochraceus, were determined in rabbits after application of the 131i labelled enzyme in therapeutic doses.1979397495
structure-activity relationships in fusidic acid-type antibiotics. 1979397741
[frequency of fungal infection in chronic bronchitis and bronchiectasis (author's transl)].among 1 161 patients with chronic bronchitis and 172 patients with bronchiectasis treated for a longer time with antibiotics or with antibiotics and corticosteroids and examined all for fungi in bronchial secretion, 34 = 0.9% showed a secondary infection with fungi (32 candida, 2 aspergillus fumigatus).1979398098
[on the contamination of the citric acid fermentation. i. the contamination by representatives of enterobacteriaceae (author's transl)].among the most dangerous bacterial contaminations of the citric acid fermentation is the so-called brown contamination, which is called forth by non pathogenic representatives of enterobacteriaceae like escherichia coli, aerobacter aerogenes, enterobacter cloacae and proteus vulgaris, while other bacteria do not produce the mentioned contamination. there is given a comprehensive characterization of the brown contamination. enterobacteriaceae interrupt the growth of the mycelium of the mold asper ...1979398647
[on the contamination of the citric acid fermentation. ii. sodium 5-nitrofurylacrylate as an antiseptic against representatives of the enterobacteriaceae (author's transl)].in context with the first communication which deals with the characterization of the so-called brown contamination called forth by enterobacteriaceae in the citric acid fermentation of molasses, the present paper describes the screening of antiseptic substances able to suppress the contamination mentioned without damaging the normal growth of the producing mould aspergillus niger and its ability of producing citric acid. among the substances tested the sodium salt of 5-nitrofurylacrylic acid (5- ...1979398648
[evaluation of antimicrobial activity of indol alkaloids].in pursuing the study of the antimicrobial properties of alkaloids prepared from cuban plants the activity of 10 indol alkaloids and 4 semisynthetic variables obtained from three plants--catharanthus roseus g. don., vallesia antillana wood and ervatamia coronaria staph, of the family apocynaceae--growing in cuba was assessed in vitro. the alkaloids and the variables used were catharantine, vindoline, vindolinine, perivine, reserpine, tabernaemontanine, tetrahydroalstonine, aparicine, vindolinic ...1979399043
protoplasts from aspergillus nidulans.a very effective lytic enzyme system for massive micro/macro-scale production of protoplasts from the filamentous fungus aspergillus nidulans is described. a striking coincidence was observed between maximal lytic activity towards aspergillus mycelium and the presece of both chitinase and alpha-(1 leads to 3)-glucanase activities. the release of protoplasts was greatly enhanced by preincubating the mycelium with 2-deoxy-d-glucose. furthermore, protoplast formation was influenced by fungal age, c ...1979399317
inhaled beclomethasone dipropionate in allergic bronchopulmonary aspergillosis. report to the research committee of the british thoracic association.a double-blind multi-centre study was carried out to assess the effects of beclomethasone dipropionate aerosol on the control of symptoms of asthma and on fungal colonization of the bronchi, in patients with allergic bronchopulmonary aspergillosis who had not been treated with an inhaled corticosteroid preparation for at least six months. each of the 32 patients who completed the trial was treated with beclomethasone (100 microgram four times daily) or placebo aerosol for consecutive periods of ...1979400108
[intracavitary inclusion]. 1979400278
characterization of rennin-like enzyme produced in submerged cultures of aspergillus niger. 1979400533
prevalence of aspergillus and candida precipitins in renal dialysis and transplant patients.serum precipitin tests to aspergillus and candida antigens were used to define the rate of infectivity with these fungal organisms in patients on renal dialysis and after kidney transplantation. a total of 58 studies in 53 consecutive patients, of whom 41.5% were post-transplant an average of 14.6 months, failed to detect significantly more precipitin activity than in a normal population. the specificity of this non-immunoreactivity was supported by the absence of clinical or post-mortem evidenc ...1979400842
immunological aspects of infection and allergy due to aspergillus species. 1978400877
mycotic infection of the paranasal sinuses. 1978400886
degradation of organophosphorus and carbamate insecticides in the soil and by soil microorganisms. 1977402103
mutant of aspergillus flavus producing more aflatoxin b2 than b1.a mutant of aspergillus flavus having a high and relatively stable aflatoxin b2/b1 ratio was recovered after treatment with nitrosoguanidine.1977402111
production of cyclopiazonic acid by aspergillus flavus link.production of cyclopiazonic acid by aspergillus flavus is reported for the first time. a procedure for its production by agitated solid substrate fermentation on red wheat is described along with the isolation procedure and physical and chemical properties of this indole derivative. the compound has been found to exert antibacterial activity.1977402112
growth, glucose metabolism and melanin formation in biotin-deficient aspergillus nidulans.biotin deficiency resulted in an increased growth rate of aspergillus nidulans. the activities of hexokinase and aldolase were not much changed during the growth cycle, but activities of glucose-6-phosphate dehydrogenase and nadp-linked glutamate dehydrogenase increased significantly during the exponential phase. this change was remarkable during biotin deficiency. in contrast to the higher growth rate and respiration rate during biotin deficiency the activities of nad(p)h oxidoreductases were l ...1977402307
glucan common to the microcyst walls of cyst-forming bacteria.chemical analysis indicated that d-glucose is tha major neutral monosaccharide present in the microcysts of a range of gram-negative bacteria. varying amounts of other neutral sugars were found. the glucose was mainly present as a glucan that could be extracted from microcysts of representative strains with alkali or mild acid treatment. the glucan could be identified as an alpha-1,3-linked polymer on the basis of (i) periodate resistance of the extracted polymer and the material present in micr ...1977402353
indirect immunofluorescent detection of antibodies against thermophilic actinomycetes in patients with hypersensitivity pneumonitis.with slide culture preparations of micropolyspora faeni, thermoactinomyces candidus, and thermoactinomyces vulgaris used as antigens, 59 sera from patients with hypersensitivity pneumonitis and 23 sera from normal controls were studied for the presence of specific antibodies by indirect immunofluorescence and immunodiffusion methods. of the 82 sera, 31 showed precipitins to m. faeni, five to t. candidus, and four to t. vulgaris. a group of 19 sera positive to aspergillus antigens showed question ...1977402432
[aflatoxins-- mycotoxins of aspergillus species]. 1977403158
[fungal spore content of the air in munich (author's transl)].a volumetric determination of seasonal variations in the fungal spore content of the air was carried out with andersen samplers (culture plates) in the center of the city of munich and 2.4 km (1.5 miles) west of it. cladosporium spores were predominant (60% altogether), followed by those of penicillium and aspergillus. up to 22 different genera were counted among the varieties. the spores of cladosporium, penicillium, aspergillus, botrytis, thysanophora and epicoccum are twice as densely represe ...1977403426
detection of aspergillus fumigatus precipitins: a comparison of counter immunoelectrophoresis and double diffusion.a counter immunoelectrophoresis method was compared with a double diffusion test for detecting aspergillus fumigatus antibodies. of 70 patients, 23 gave positive results in both tests and the remainder gave negative results. fifteen patients with proven aspergillosis gave positive results in both tests.1977404338
soluble amino and carbohydrate compounds in the testae of six experimental peanut lines with various degrees of aspergillus flavus resistance. 1977404344
the diagnosis of aspergillus fumigatus infection of the nasal chambers of the dog with particular reference to the value of the double diffusion test. 1977404470
bioconcentration of toxaphene by microorganisms. 1977405061
studies on the restoration of the activities of ribonucleases by polyamines in the presence of various ribonuclease inhibitors.the effect of polyamines on ribonucleases in the presence of various inhibitors (poly(g), heparin, and rat liver rnase inhibitor) has been studied. bovine pancreatic rnas a and a ribonuclease from horse submaxillary gland (rnase hs) were inhibited by the inhibitors, but rnase t1 and rnase m were not inhibited. polyamines were found to restore the activites of rnase a and rnase hs inhibited by poly(g) or heparin but not those activities inhibited by rat liver rnase inhibitor. when poly(u) and pol ...1977405377
factors affecting aflatoxin contamination of cottonseed i. contamination of cottonseed with aspergillus flavus at harvest and during storage. 1977405413
toxigenic fungi in food and foodstuffs of thailand a re--evaluation of its pathologic features. 1977405448
experimental aspergillosis in buffaloes: histopathological, histochemical and serological studies. 1977405583
[paronychia caused by aspergillus flavus link]. 1977405584
modification of the radiation resistance of aspergillus flavus mycelial units by some chemicals.survival curves for the mycleium of aspergillus flavus link var. columnaris raper and fennell were constructed after irradiation with gamma rays in the presence of nacl, nabr, nai, kcl, kbr, ki, cacl2, cabr2, cai2, ca(no3)2, nano2, nano3, kno2, iodoacetic acid, iodoacetamide and vitamin k5. in addition iodized salt was also tested. all the chemicals tested exhibited initial toxicity at zero dose. however, most of the chemicals demonstrated a synergism when present during irradiation. compounds c ...1977405704
[aminopeptidase system of aspergillus flavus].the aminopeptidases system contained in a complex of exocellular peptidhydrolases synthetized by asp. flavus was studied. separation of the system into individual enzymes of the type of leucin aminopeptidase, aminotripeptidase and specific leucyl-glycyl-glycine-aminopeptidase by the methods of salt fractionation. deae-sephadex a-50 and deae-cellulose chromatography. these enzymes are characterized by a different degree of purification as well as by the presence of the multiple forms, anion and c ...1977405779
interference of cellular ferric ions with dna extraction and the application to methods of dna determination. 1977405886
natural occurrence of sterigmatocystin in in-shell pecans.the natural occurrence of sterigmatocystin (s) in in-shell pecans is reported. aspergillus versicolor was not isolated from contaminated samples. incidence of a. flavus and a. glaucus, species known to produce sterigmatocystin under laboratory conditions, was high (43 and 35%, respectively). isolation data suggest sterigmatocystin may have been produced by one or both of these species.1977406023
genetic analysis of a mutant of aspergillus flavus producing more aflatoxin b2 than b1. 1977406559
relation of lipids to the action of streptomycin on bacillus subtilis and escherichia coli and griseofulvin and fungizone on aspergillus niger.an attempt was made to reveal the relation between the lipid content and components of b. subtilis and e. coli and the action of streptomycin, and those of a. niger and the action of griseofulvin and fungizone (amphotericin b). total lipids were extracted in co2 atmosphere, dried, and weighed. lipid components were analyzed by thin-layer chromatography. complements to the growth medium of a. niger with extracted total lipids and phospholipids were made to verify the obtained results. it has been ...1977406753
new species of aspergillus producing sterigmatocystin.a number of species belonging to the genus aspergillus were evaluated for their toxicity to ducklings and the ability to produce sterigmatocystin. three new species capable of producing sterigmatocystin were found, namely, aspergillus aurantio-brunneus, aspergillus quadrilineatus, and aspergillus ustus. all three were toxic to ducklings. the production of sterigmatocystin by aspergillus rugulosus was confirmed, and the toxicity of aspergillus stellatus and aspergillus multicolor is described.1977406838
reverse phase analytical and preparative high pressure liquid chromatography of aflatoxins. 1977408324
modified indirect fluorescent-antibody test for aspergillosis.diffuse fluorescence in an indirect fluorescent-antibody test for antibody to aspergillus fumigatus was eliminated by using germlings, rather than hyphae, as antigen. the modified method yielded diagnostic titers larger than or equal to 1:32 in 24 of 25 known cases, was highly specific, and showed good correlation with clinical status and results of immunodiffusion. this technique, which uses the germling antigen, inactivation of test serum at 59 +/- 1 degrees c, and anti-immunoglobulin g conjug ...1977408374
[study of the chemical makeup of lignin after fungal infestation by aspergillus flavus and a. niger]. 1977408590
effect of systemic antibiotics on the microbial flora of the external ear canal in hospitalized children.the effect of antibiotic therapy and hospitalization on the external ear canal flora was investigated in 131 children. fifty-eight percent of the patients receiving antibiotic therapy had gram-negative bacilli or yeasts in their external ear canal, compared with 17% of the patients who were hospitalized for ten days or longer and only 3% of the patients who were hospitalized for short periods. antibiotic therapy is the major factor in determining the colonization rate of the external ear canal w ...1977408786
a quantitative evaluation of the antifungal properties of glutaraldehyde. 1977409708
variability of extracts used in immunoprecipitin tests.immunodiffusion reactions of several different commercial fungal extracts from organisms were compared to those obtained from patients' environments. sera were obtained from patients suspected of having hypersensitivity lung disease (hld). there was a difference in reactivity among the sources of the antigen and in some lots of antigen from the same commercial supplier. the results demonstrate a wide variation in the reactivity of different antigenic extracts and emphasize the need for uniform s ...1977409751
occurrence of a major protein associated with fruiting body development in neurospora and related ascomycetes.electrophoretic and immunological analysis of fruiting body (perithecial) extracts demonstrates the occurrence of a major phase-specific perithecial protein in all neurospora species and in the closely related gelasinospora cerealis and sordariafimicola. the perithecial proteins from these different species fall into a number of groups with different electrophoretic mobilities. they appear to be immunologically closely related but not identical to one another even within the same genus, with onl ...1977410027
[investigations on the antimicrobial activity of amin-aldehydecondensates. 1. (communication:) symmetrically substituted animals of formaldehyde (author's transl)].in the scope of our research about the antimicrobial activity of aldehyde-amin-condenates a number of partly new aminals was synthesized by reaction of formaldehyde with various secondary amines. structures and physically constants are shown in the tables 1 and 2. the antimicrobial activity is demonstrated by the results of the disk-test (table 3), of the minimal inhibition concentration (mic, talbe 4) and the suspension and area disinfecting test following the method of the dghm (tables 5 and 6 ...1977410200
strontium-87m lung scans in pulmonary aspergillosis.experimental observations have indicated that radioactive strontium localizes in lesions infected with aspergillus species. preliminary clinical studies have recommended use of strontium lung scanning to evaluate patients thought to have pulmonary manifestations of aspergillosis. in view of the difficulty in accurately interpreting the clinical significance of recovery of aspergillus species from sputum of patients with pulmonary disorders as well as the varied clinical presentations of pulmonar ...1977410255
[lipolysis and aflatoxin production in aspergillus flavus (author's transl)].lipolysis in relation to toxinogenesis has been studied in various strains of aspergillus flavus. toxinogenic strains show a lipolytic activity which is twice the activity of non-toxinogenic strains. this enzymatic activity seems to be directly linked to the biosynthesis of toxins.1977410341
[large-scale purification, crystallization and some physicochemical properties of extracellular guanyl-rnases c2 and pch1].the purification of rnase c2 from 76.5 1 of asp. clavatus cultural fluid and rnase pch1 from 160 1 of pen. chrysogenum 152 a cultural fluid was described. 1150-fold purification of rnase c2 was attained by precipitation with ammonium sulfate, ion-exchange chromatography and rechromatography on deae-cellulose, gel chromatography on sephadex g-75, and crystallization from diluted acidic buffer. during the preparation of rnase pch1 additional chromatography on cm-cellulose was used before crystalli ...1977410458
reduction of sterigmatocystin and versicolorin a hemiacetals with sodium borohydride. 1977410911
opportunistic mycotic osteomyelitis: bone infections due to aspergillus and candida species. 1977411015
clinical and therapeutic significance of patterns of allergic reactions of the lungs to extrinsic agents: the 1977 j. burns amberson lecture. 1977411403
partial characterization of the mode of action of benzoic acid on aflatoxin biosynthesis.aflatoxin production by a toxigenic strain of aspergillus flavus was greatly reduced by benzoic acid and sodium benzoate in synthetic media. the reduction was accompanied by the appearance of a yellow pigment. spectral analyses partially characterized this pigment as closely related to an acetyl derivative of a versiconal-type compound. a cell-free extract prepared from a. flavus grown in synthetic media was active in converting this yellow compound into aflatoxin b1 in the presence of reduced n ...1977411562
electrophoretic variation in esterases in 3 wild-type and respective mutant strains of aspergillus flavus.wild-type strains and auxotrophic mutants of aspergillus flavus, differing regarding aflatoxin production, were tested for esterases isozymes. esterases variation was found in all strains used, and a possible correlation between the pattern of esterase bands and aflatoxin production is suggested.1977411683
evidence for the parasexual cycle in a strain of aspergillus flavus containing virus-like particles.eight isolates of a. flavus and a. parasiticus were screened for the presence of virus-like-particles (vlp). only a. flavus strain nrrl 5565 contained detectable vlp. spore color and auxotrophic mutants were induced in this strain and evidence for the parasexual cycle was obtained. attempts to form heterokaryons between 3 auxotrophs of the vlp-containing strain and 9 auxotrophs from two different aflatoxigenic strains were unsuccessful.1977412103
simple and rapid colorimetric method for the microdetermination of alpha amylase. 1977412348
degradation of the plant flavonoid phellamurin by aspergillus niger.we have previously described the structure of phellamurin, a plant flavonoid, as 3,4',5,7-tetrahydroxy-8-isoprenylflavanone-7-o-glucoside (17). degradation of phellamurin by aspergillus niger using modified czapek-dox medium as well as phellamurin or one of its degradation products as a sole carbon source, is reported here. eleven compounds are identified from phellamurin degradation products. a. niger apparently decomposes phellamurin by first removing glucose with beta-glucosidase; neophellamu ...1977412468
a comparative investigation of the bactericidal and fungicidal effects of three phenolic disinfectants. 1977412825
sensitivity to 5-fluorocytosine and virulence for mice of some human isolates of aspergillus.the sensitivity of 5-fluorocytosine (5-fc) and the virulence for mice was assessed for 16 human isolates of aspergillus: a. fumigatus 2, a. niger 7, a. flavus 4, a. terreus 2 and a. conicus (a. restrictus group) 1. fourteen strains were recovered from ear exsudates, 1 from sputum and 1 from the pus of mastoid cells of an autopsy case with meningeal and cerebral involvement. nine of them, which included strains of a. fumigatus and a. niger were sensitive to 5-fc (m.i.c. less than or equal to 6.4 ...1977413042
[level of antibodies to aspergillus flavus in women and the incidence of various disorders of reproductive functions]. 1977413102
the use of fungal protoplasts in the study of aflatoxin biosynthesis.protoplasts derived from aspergillus flavus are shown to be capable of synthesizing aflatoxins when incubated in a chemically defined medium. 14c-acetate and 14c-versicolorin a, added to protoplasts from 3-day-old mycelium, are incorporated into aflatoxin b1.1978413736
examination of fungal growth and aflatoxin production on marihuana.under favorable growth conditions, aspergillus flavus and a. parasiticus produced aflatoxins on marihuana. cultures of a. flavus atcc 15548 produced both aflatoxin b1 (afb1) and g1 (afg1). the production of afg1 was substantially greater than that of afb1. cultures of a. flavus nrrl 3251 and a. parasiticus nrrl 2999 produced only afb1. all natural flora cultures tested negative for aflatoxins. no aspergilli sporulations were observed in these cultures. in the cultures inoculated with known toxig ...1977414138
[mycologic study of the bronchial aspirates of patients with chronic lung diseases]. 1977414489
dual skin test reactions and serum antibodies to subtilisin and aspergillus fumigatus extracts. 1978414857
genetics of aflatoxin production in aspergillus flavus: linkage between a gene for a high b2:b1 ratio and the histidine locus on linkage group viii. 1977415234
the effect of various antifungal agents on aflatoxin production and growth characteristics of aspergillus parasiticus and aspergillus flavus in liquid medium.various antifungal agents were added to a medium of 2% yeast extract-4% sucrose. spores of a toxigenic strain of aspergillus parasiticus were inoculated into the medium and incubated at 26 degrees c. for 10 days. growth of the mold and aflatoxin formation were monitored every 48 hours during the experiment. of the antifungal agents evaluated, propionic acid and crystal violet were the most effective compounds in retarding mold growth. propionic acid was fungicidal at concentrations greater than ...1977415299
[aflatoxinogenic fungi in the human and animal environment]. 1977415338
a primate model of allergic bronchopulmonary aspergillosis.allergic bronchopulmonary aspergillosis (aba) in man is featured by the presence of ige skin sensitizing and igg precipitating antibodies against aspergillus fumigatus (af). an animal model of this disease was created. 2 monkeys immunized with af produced igg-precipitating antibody. normal human serum was infused into both immunized and unimmunized monkeys and allergic human serum containing a high titer of ige against af was infused into another pair of immunized and unimmunized monkeys. all mo ...1978415985
culture and antigen variants of aspergillus. 1978416063
specific double diffusion microtechnique for the diagnosis of aspergillosis and paracoccidioidomycosis using monospecific antisera.using experimental reference sera against species-specific antigens of aspergillus fumigatus and paracoccidioides brasiliensis in a microdouble diffusion technique, a simple and specific test for the immunodiagnosis of aspergillosis and paracoccidioidomycosis has been developed. only sera that produced lines of identity with either one of the bands formed by the anti-c2 or the anti-e2 reference sera were considered positive for aspergillosis or paracoccidioidomycosis, respectively. the sensitivi ...1978416505
[pulmonary and hepatic aspergillomas in the deer].four solitary aspergillomas in deer are being described. two were found in the lungs and two in the liver. morphologically, they were bulky, local lesions filled with homogenous, fragile, necrotic tissue of conspicuously green color. pulmonary aspergillomas communicated with the conducting bronchus having affected fibers. the necrotic tissue of aspergillomas was interwoven by diffuse abundant fibers of aspergillus fumigatus.1978416550
incidence of airborne aspergillus flavus spores in cornfields of five states.airborne aspergillus flavus spores were rarely detected throughout the 1975 growing season by the agar plate method at cornfield sites in georgia, illinois, maryland, south carolina, and virginia.1978416756
[use of cell cultures and chick embryos for evaluating the toxicity of the aspergillus flavus group isolated from food products]. 1978416994
radioprotective effect of aspergillus flavus.a study designed to determine the extent and intensity of radioprotective effects of the mold conidium a. flavus in white mice revealed a higher survival rate with irradiation doses in the range of ld70-ld90; with irradiation with supralethal doses there is no difference in survival by stimulated and control mice. the radioprotective effect is independent of whether the strain a. flavus had been isolated from environment with enhanced radioactivity or not. it depends on a structure of the wall o ...1978417272
time dependence of radioprotective effects of a. flavus conidia.no essential difference in radioprotection results when conidia of a. flavus are applied to mice within a time lapse of a few minutes up to 48 hours prior to irradiation. when applied 72 hr before irradiation, they fail to affect mouse resistance. application of conidia provide no protection to mice irradiated for 18-20 hr at the dose rate of 1 r/min; similarly ineffective are the chemoprotectors cistafos and mexamine. a combined administration of conidia and the two protective substances increa ...1978417273
evaluation of methods to detect antibodies against aspergillus fumigatus.seventy-five sera, including sera from 23 patients with aspergillosis, 17 with tuberculosis, asthma or carcinoma, and 35 normal controls, were studied for antibody activity against aspergillus fumigatus by agar gel double diffusion (dd), counterimmunoelectrophoresis (cie), indirect hemagglutination (iha) and indirect immunofluorescence (if). metabolic antigens produced from a selected strain of a. fumigatus were used for dd, cie and iha, while slide cultures of the same organism were used for if ...1978417619
metabolic products of microorganisms 167. cyclopaldic acid from aspergillus duricaulis. 1. production, isolation and bioloical properties.in the course of a screening for new metabolites from fungi we isolated a substance with antimicrobial activity from cultures of aspergillus duricaulis (cbs 481.65) (tü 679). it was antagonized by putrescine, spermidine, spermine, arginine, citrulline, lysine, ornithine, in higher concentration by aspraagine and glutamine too. the effect of ethylenediaminetetraacetate on the susceptibility of streptomyces viridochromogenes (tü 57) and bacillus subtilis atcc 6051 to this antibiotic has been studi ...1978417692
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