Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| dynamics of non-specific antibacterial activity of the peritoneal cells of mice induced with coxiella burnetii antigen. | it was found that primary immunization with coxiella burnetii antigen increased mouse resistance to salmonella typhimurium infection as evidenced by acceleration of bacterial elimination from the peritoneal cavity and a decrease in lethality of experimental animals. the existence of two rises of bactericidal activity of mouse peritoneal cells was ascertained: the "early" on days 1 and 2, and the "late" on day 14 after c. burnetii administration. the first rise was accompanied by some increase in ... | 1992 | 1350168 |
| ultrastructure of viable and inactivated coxiella burnetii after inoculation of mice. | c3ha mice were inoculated intraperitoneally (i.p.) with viable coxiella burnetii (c.b.) (strain apodemus flavicollis-luga, phase i) or c.b. antigen (formalin-inactivated c.b.); pieces of spleen, liver, omentum, kidney, and suspension of peritoneal macrophages were examined by electron microscopy at 1, 7, 14, 21, 28, and 42 days post-infection (p.i.). two main types of viable c.b. cells--small dense (dc) and bacteria-like (bc)--were found in omentum, spleen, and peritoneal exudate cells beginning ... | 1992 | 1350169 |
| immunoblot analysis of antibody response in mice infected with coxiella burnetii phase i. | mouse sera collected from day 4 to day 133 postinfection (p.i.) with phase i coxiella burnetii strain nine mile were analysed by immunoblotting with phase i c. burnetii cell lysate. antibodies of igg class protein antigens were revealed already on day 10 p.i. (60, 49 and 27 kd proteins), followed by those to 77 kd protein from day 18 p.i. and to further 7 (from 42 to 70 kd) proteins from day 28 p.i. igg antibody reaction was observed also with 5 antigens in 14-20 kd region corresponding to lipop ... | 1992 | 1350170 |
| phenotypic and genotypic heterogeneity of 8 new human coxiella burnetti isolates. | eight new strains of coxiella burnetii were isolated from chronic q fever patients using centrifugationashell vial technique. seven patients had endocarditis (including one patient with an immunodeficiency syndrome), and one had a vascular prosthesis infection. three prototype strains, nine mile phase ii, q212 and priscilla and eight new isolates were cultured in l 929 cells. heterogeneity of their cytopathic effect was observed. dnas of the eleven strains have been isolated and purified by stan ... | 1992 | 1350176 |
| immunoblot analysis of igg subclass antibody response against coxiella burnetii in balb/c mice. | balb/c mice were inoculated with live or inactivated organisms of coxiella burnetii, strain nine mile, phase i. sera collected after different time intervals were subjected to immunoblot analysis and results compared with elisa values. immunoblots were performed with different horseradish peroxidase labelled conjugates (goat anti-mouse igg1, igg2a, igg2b, igg3) and results monitored and analysed by laser densitometry. elisa analysis was performed using the same peroxidase labelled goat anti-mous ... | 1992 | 1350177 |
| influence of coxiella burnetii infection of male mice on their offspring. | the dramatic spread of q fever in poland among cattle kept in isolation from natural environment (ticks, wild animals) has suggested the possibility that the infection may also be transmitted sexually. to test this hypothesis series of experiments have been performed in controlled laboratory conditions. male mice infected with c. burnetii were allowed to mate with healthy female mice. on day 18 of pregnancy serum igm antibodies to c. burnetii antigens and bacteria in spleen, liver and placenta w ... | 1992 | 1350178 |
| dna probes for detecting coxiella burnetii strains. | methods have been developed for the rapid detection of c. burnetii by specific hybridization of labelled dna probes to rickettsial plasmid dna sequences present in clinical samples. one dna probe detects all c. burnetii strains, while additional probes differentiate, between organisms associated with chronic or acute disease. using these probes, c. burnetii can be identified in blood, urine, and tissue samples. the plasmid-derived dna probes detect as few as 10(4) organisms and less than 1 ng of ... | 1992 | 1350179 |
| gene transfer, replacement and augmentation. keystone symposia on molecular and cellular biology. april 3-9, 1992. abstracts. | 2006 | 1351967 | |
| molecular characterization of cloned variants of coxiella burnetii isolated in china. | to study the molecular properties of coxiella burnetii phase variants we cloned the phase variants of c. burnetii qiyi (cbqy) strain by the red plaque technique. three cloned strains, cbqyic3 (phase i), cbqyiic7 (phase ii) and cbqyiic5 (semirough-phase) were analysed by sds-page, immunoblot assay, plasmid isolation and agarose gel electrophoresis of dna restriction fragments. the results suggest that the unique phase-dependent substance is a lipopolysaccharide and that most protein components of ... | 1992 | 1359769 |
| basic structural features of a lipopolysaccharide from the coxiella burnetii strain nine mile in the virulent phase i. | 1992 | 1359776 | |
| abnormal chromosome complement after normal amniocentesis result. | 2006 | 1360083 | |
| a randomized trial of reduced doses of azidothymidine in japanese patients with human immunodeficiency virus type 1 infection. | adverse reactions to the standard dose (1,200 mg/day-1,500 mg/day) of azidothymidine (azt) are serious. an in vitro pharmacokinetic study of intracellular azt-5'-triphosphate suggested the feasibility of a clinical trial with reduced doses of azt. a randomized trial with reduced doses of azt (group a; 400 mg/day, n = 15, group b; 800 mg/day, n = 13), was conducted enrolling 28 patients with human immunodeficiency virus infection. the effective rate of azt on cd4+ lymphocyte counts was similar fo ... | 1992 | 1360277 |
| study of cross-reaction between coxiella burnetii and legionella pneumophila using indirect immunofluorescence assay and immunoblotting. | patients with q fever and legionellosis may present identical clinical symptom. differentiation of these diseases is made by serology, mainly the indirect immunofluorescence assay (ifa). using ifa the authors tested 154 q fever positive sera from 55 patients with acute q fever and 28 patients with chronic q fever for legionella pneumophila antibodies and 57 sera from 57 patients with legionellosis for coxiella burnetii antibodies. of the 211 sera tested, four sera from different patients had ant ... | 1992 | 1364022 |
| attempt to infect hunterellus hookeri howard (hymenoptera, encyrtidae), an endoparasite of ticks, with coxiella burnetti. | 1992 | 1364029 | |
| an enhanced-response system for performing chemiluminescent and bioluminescent tests. | 2006 | 1366493 | |
| [initial experiences with a self-expanding metal stent in malignant ureteral compression]. | self-expanding metallic stents for the treatment of hydronephrosis were implanted in 12 ureters with malignant compression in 10 patients. in 3 ureters the stents were introduced percutaneously by a transrenal route; in 8 ureters introduction was transurethral and in one ureter by a combined route. patency rate after 6 months was 90.9%. in all cases the stent was able to withstand pressure by the tumour for the remainder of the patient's life. in one patient there was incrustation of both stents ... | 2005 | 1370762 |
| piscirickettsia salmonis gen. nov., sp. nov., the causative agent of an epizootic disease in salmonid fishes. | a novel intracellular pathogen morphologically similar to the ehrlichiae has been isolated in cell culture and identified as the cause of an epizootic disease of salmonid fish. like the ehrlichiae, the salmonid pathogen, designated strain lf-89, replicates within membrane-bound cytoplasmic vacuoles in host cells. this agent is the first with characteristics of this type to be isolated from a fish. analysis of the lf-89 16s rrna indicated that, unlike the ehrlichiae, lf-89 is a gamma proteobacter ... | 1992 | 1371057 |
| comparison of the self-image of teenagers in finland, the united states, and germany. | in this research, the self-image of finnish adolescents was compared with the self-images of american and west german adolescents. results show that there are statistically significant differences between finnish adolescents and american adolescents in five areas. finnish adolescents are emotionally healthier than american adolescents, and their mood is better. american adolescents have higher vocational and educational goals than finnish adolescents, and their adaptation skills to immediate env ... | 2006 | 1390794 |
| [acute arthritis associated with q fever]. | 1992 | 1391011 | |
| [seroprevalence of q fever among the adult population of lanzarote (canary islands)]. | q fever is an endemic zoonosis in the canary islands. in 1986, we detected, in a pilot study, residual antibodies of the infection in 3% of the population from lanzarote. in 1989, we performed a new study in order to assess seroprevalence of q fever among the adult native population from the island. we studied 390 human serums obtained from an statistically representative sample. age ranged from 30 to 64 years. out of 390 serums, 196 (50.25%) were obtained from men and 194 (49.74%) from women. t ... | 1992 | 1391577 |
| [prolonged febrile syndrome as a manifestation of coxiella burnetii infection, presentation of infrequent clinical cases]. | we present two cases of infection by coxiella burnetii which developed with sustained fever symptoms. during its evolution, the first case presented granulomatous hepatitis, whereas the second case presented left cosofemoral arthritis. we describe the clinical-evolutive characteristics of these clinical forms and within the evolution of the chronic forms of q fever. | 1992 | 1391579 |
| negligence: case for the defence. | 2006 | 1393213 | |
| monoclonal antibody based capture elisa/elifa for detection of coxiella burnetii in clinical specimens. | a capture elisa/elifa system based on monoclonal capture and biotinylated monoclonal detection antibody is described. the assay is fast, highly specific and detects a minimum dose of 2500 coxiella (c.) burnetii particles. in contrast to the sophisticated and cumbersome isolation procedures, even non-specialized laboratories could use this assay system for investigating clinical samples of different origin for c. burnetii within a short period of time. | 1992 | 1397227 |
| [celioscopic cholecystectomy. a survey of the french society of endoscopic surgery and operative radiology. apropos of 937 cases]. | twenty-eight surgeons, members of the société française de chirurgie endoscopique et de radiologie opératoire, took part in this multicenter study, carried out between march 1989 and january 1991. nine hundred and thirty-seven patients were entered into the study, 934 of whom presented with biliary lithiasis and 3 with gallbladder polyps. biliary colic was found in 918 (98 percent) of patients. one hundred and twenty-five patients (13.3 percent) presented with acute cholecystitis. laparoscopic c ... | 2006 | 1397847 |
| enzyme immunoassay for q fever: comparison with complement fixation and immunofluorescence tests and dot immunoblotting. | enzyme-linked immunosorbent assays (elisa) for the detection of specific immunoglobulin g (igg) and igm antibodies were developed by using purified coxiella burnetii cells. variables, including type of microtiter plate, blocking agent, incubation conditions, antigen stability, and substrate type, were examined to achieve optimal elisa performance. the reliabilities of the assay systems were compared with those of complement fixation (cf) and enhanced immunofluorescence (eif) tests with 600 human ... | 1992 | 1401014 |
| detection of coxiella burnetti by dna amplification using polymerase chain reaction. | the polymerase chain reaction (pcr) was used for the detection of coxiella burnetti, an obligate intracellular bacterium and the etiologic agent of q fever. a pair of primers derived from the c. burnetii superoxide dismutase gene served to amplify a targeted 257-bp fragment of genomic dna. these primers were chosen on the basis of genbank analysis, g + c ratio, and absence of secondary structure. this technique allowed the detection of as few as 10 c. burnetii organisms. c. burnetti was detected ... | 1992 | 1401016 |
| phagolysosomal alkalinization and the bactericidal effect of antibiotics: the coxiella burnetii paradigm. | most infections due to intracellular bacteria respond poorly to antibiotic treatment. the chemical conditions within the subcellular site of bacteria may change antibiotic activity. coxiella burnetii multiplies within phagolysosomes. the antimicrobial activity of antibiotics combined with the lysosomotropic agents amantadine (1 microgram/ml), chloroquine (1 microgram/ml), and ammonium chloride (1 mg/ml), which alkalinized coxiella burnetii-containing phagolysosomes from ph 4.8 to 5.3, 5.7, and 6 ... | 1992 | 1402021 |
| a simple method for amplification of dna from paraffin-embedded tissues. | 1992 | 1408846 | |
| miliary tuberculosis involving the brain: mr findings. | 2004 | 1414778 | |
| epidemiologic features and clinical presentation of acute q fever in hospitalized patients: 323 french cases. | to contribute to the knowledge of epidemiologic and clinical features of patients hospitalized with q fever in france. | 1992 | 1415306 |
| t-lymphocyte stimulation by microbial superantigens. | 2006 | 1418619 | |
| susceptibility of some species of rodents to rickettsiae. | the present study was designed to test the susceptibility of free-living rodents, viz apodemus flavicollis, microtus arvalis, clethrionomys glareolus, mus musculus, and outbred white mice from dobrá voda farm, csfr, to coxiella burnetii, rickettsiae of the spotted fever group (rickettsia sibirica, r. conorii, r. slovaca and r. akari) and rickettsiae of typhus group (r. typhi and r. prowazekii) by various routes of administration. the highest levels of antibodies to c. burnetii were found in a. f ... | 1992 | 1427494 |
| rapidly fatal q-fever pneumonia in a patient with chronic granulomatous disease. | acute q-fever is a systemic illness which rarely has a fatal outcome. fatal cases do occur with the chronic form of the disease and associated with endocarditis. this report presents the case of a fatal, acute q-fever pneumonia in an 11-year-old patient with chronic granulomatous disease. complement fixation antibody titer rose to 1:1,024 with positive igm in immunofluorescence. giemsa stained lung sections and indirect immunofluorescence demonstrated the microorganisms in the tissues. the coxie ... | 1992 | 1428185 |
| structure and function of the cd16:zeta:gamma complex expressed on human natural-killer cells. | natural-killer (nk) cells are large granular lymphocytes involved in host defense against tumor cells and virally-infected cells. in addition to natural cytotoxicity, nk cells can effect antibody-dependent cytotoxicity mediated by cd16 (fc gamma riiia alpha). it has recently been shown that cd16 is associated with disulfide-linked dimers composed of 2 homologous sub-units, zeta and gamma. these transducing molecules are also associated with other multimeric cell-surface receptors such as the t-c ... | 1992 | 1428397 |
| [is a29, b12 vasculitis caused by the q fever agent? (coxiella burnetii)]. | the authors describe the first two cases, to their knowledge, of retinal vasculitis, associated with q fever. the first case was a chronic infection induced by coxiella burnetii associated with hla group a29 and b12; in the second case, the phenotype was b12. the authors tried to determine whether this agent could be the "birdshot chorioretinopathy" promoting factor. several epidemiologic findings tend to prove that q fever is not the only cause. on the other hand, its similarity with rickettsia ... | 1992 | 1430809 |
| tragedy of the commonplace: the impact of addiction on families in the fiction of thomas hardy. | 2006 | 1434778 | |
| late airway changes caused by chronic rejection in rat lung allografts. | airway disease after lung or heart-lung transplantation is one of late major complications, affecting the prognosis of the transplants. little is known about the causes of airway changes. we performed rat lung transplantation and investigated the late airway changes of the long-term surviving lung grafts: allografts, bn to lewis; isografts, bn to bn rat. all recipients were treated with csa. we found airway changes, i.e., mucosal ulceration, granulation, submucosal fibrosis, which was located in ... | 1992 | 1440846 |
| spontaneous splenic rupture complicating acute q fever. | q fever is usually a self-limited febrile illness that involves the lungs and the liver. acute complications are rare. we present the case of a 30-yr-old patient with spontaneous splenic rupture during the course of acute q fever infection. he was admitted to the hospital with high temperature and the radiological signs of an atypical pneumonia. forty-eight hours after admission, he developed shock. because of free intraabdominal liquid, a laparatomy was performed that revealed a tear in the enl ... | 1992 | 1442694 |
| "raynaud's disease" in migraineurs: one entity or two? | two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ... | 2006 | 1446993 |
| q fever endocarditis: diagnostic approaches and monitoring of therapeutic effects. | the scope of current diagnostic methods for q fever endocarditis includes serology, direct demonstration of coxiella burnetii in the resected heart valve tissue, and animal inoculation studies. illustrated by a clinical case report, the different methods are presented and discussed. serology represents the primary method, using the techniques of complement fixation, indirect immunofluorescence, and enzyme-linked immunosorbent assay (elisa). the latter two techniques allow the detection of immuno ... | 1992 | 1450617 |
| phagolysosomes of coxiella burnetii-infected cell lines maintain an acidic ph during persistent infection. | coxiella burnetii, the agent of q fever, is an obligate intracellular bacterium that multiples within vacuoles of phagolysosomal origin. persistently infected cell lines were maintained in continuous culture for months. we studied the ph of the phagolysosomes by using two murine cell lines during early propagation of the bacteria and after establishment of persistent infection. three strains of c. burnetii were studied because of the purported propensity of each strain to cause acute or chronic ... | 1992 | 1452331 |
| histological and immunocytochemical characterization of coxiella burnetii-associated lesions in the murine uterus and placenta. | the fetoplacental units and the postgravid uterus of balb/cj (h-2d) mice inoculated intraperitoneally with coxiella burnetii (nine mile isolate, phase i) on day 6 of pregnancy were examined histologically and immunocytochemically at 1 to 160 days postinoculation. clinically, abortions, stillbirths, and perinatal deaths were observed. histological lesions in the placenta were characterized by severe necrosis of the decidua basalis and the labyrinth, fibrinoid degeneration of decidual vessels, and ... | 1992 | 1452356 |
| laboratory outbreak of q fever. | an outbreak of q fever in a university department where sheep placentas were being used for research is described. of six persons exposed to the sheep, four had positive titers with only one person developing an acute febrile illness and liver disease. this report illustrates the value of the family physician obtaining an occupational history and conducting an outbreak investigation. | 1992 | 1453153 |
| [the role of tumor necrosis factor and interleukin-1 in forming resistance in experimental q fever]. | preliminary injections of human recombinant tumor necrosis factor (tnf-alpha) and interleukin 1 (il-1 beta) increases the resistance of guinea pigs to coxiella burnetii. the increase of this resistance depends on the dose of cytokines and the time of their inoculation. | 1992 | 1455970 |
| sister chromatid exchange (sce) frequency in lymphocytes of patients with colorectal carcinoma treated with razoxane. | the increased risk of neoplasia following cytotoxic therapy for both malignant and nonmalignant disease is well known. sister chromatid exchange (sce) frequencies in patients receiving such chemotherapy are often elevated, and the persistence of high levels after treatment may provide an indicator for susceptibility to secondary neoplasia. the cytostatic drug razoxane has been used for the treatment of psoriasis, acute myeloid leukemia (aml), and colorectal carcinoma. prolonged use of this drug, ... | 2006 | 1458513 |
| interlaboratory study of the ifcc method for alanine aminotransferase performed with use of a partly purified reference material. | we present the results of a study on performance of a reference material for alanine aminotransferase (alt, ec 2.6.1.2) and the corresponding ifcc-approved method in an interlaboratory trial involving 13 laboratories. the alt material was partly purified from pig heart (specific activity, 150 ku/g) and was essentially free of six potentially contaminating enzyme activities, including aspartate aminotransferase (ec 2.6.1.1). the partly purified alt was lyophilized in a triethanolamine-buffered ma ... | 1992 | 1458569 |
| increased tissue concentrations of the gastrin precursor in patients treated with omeprazole. | the main form of gastrin in antral mucosa, the amidated heptadecapeptide g17, is generated from an inactive precursor, progastrin, by steps involving endopeptidase cleavage and amidation. gastrin cells are normally inhibited by gastric acid and in this study we have examined how suppression of acid by treatment with omeprazole for 6-8 weeks influences gastrin production in patients with oesophagitis. plasma concentrations of total amidated gastrins in the fasting state increased from 18 to 43 pm ... | 2006 | 1459168 |
| morbidity from childhood to adulthood. the medical life history of 103 patients. | the aim of the study was to investigate the relationship between presented morbidity in consecutive periods of time in the first 35 years of life. data were collected in a large rural general practice from 1946 to 1990 and covered 103 persons born between 1946 and 1959 in a general practice in the east of the netherlands. morbidity scores were calculated for all registered diagnoses in 5-year periods. morbidity was allocated to three degrees of seriousness, to all atopic disorders, and to eight ... | 2006 | 1459384 |
| unusual presentation of tuberculous peritonitis. | 1992 | 1459703 | |
| [seroepidemiological studies on the detection of q fever in sheep in middle thuringia]. | in a random samples test altogether 4337 sheep of varying ages from several herds of different sizes in the middle region of thuringia were investigated with complement fixing test for the existence of q fever. in 47.1 per cent of the tested herds and in 5 from 8 of the included districts q fever reagents were provable. the serological detection quota of all tested sheep amounts to 1.11 per cent, but the percentage of serological reagents in mother-sheep was 1.36 per cent, in the female young sh ... | 1992 | 1463436 |
| successful treatment of bile duct injury inflicted during laparoscopic cholecystectomy by endoscopic retrograde biliary drainage. | 2006 | 1468404 | |
| reactivation of q fever following cardiac surgery. | to determine whether reactivation of q fever occurs following cardiac surgery 43 patients who had antibodies to coxiella burnetii were identified pre-operatively. serum samples were collected 1, 4 to 6, and 24 weeks post-operatively. one patient had active q fever endocarditis. seven of the remaining 42 (17%) had a > or = fourfold rise in titres for antibodies to coxiella burnetii post-operatively. only two of these seven had an increase in antibody titres for other agents suggesting that the fo ... | 1992 | 1468423 |
| foreign body of the skull base due to transorbital penetrating trauma. | 2006 | 1470461 | |
| seroepidemiology of coxiella burnetii in domestic and companion animals in japan. | 1992 | 1471330 | |
| work related disorders of the upper limb. | 2006 | 1472247 | |
| specific and nonspecific effects of ethanol vapor on plasma corticosterone in mice. | the intent of this study was to determine whether chronic ethanol (etoh) vapor inhalation, with or without adjunct pyrazole (pyr) administration, was stressful in mice, as defined by increases in plasma corticosterone (cort) concentration. mice were randomly assigned to groups differentiated both on the basis of etoh vapor exposure and the presence or absence of pyr administration. blood samples for blood etoh concentration (bec) and plasma cort concentration were obtained from mice after 72-96 ... | 2006 | 1472310 |
| fibrin ring granulomas in hepatitis a. | fibrin ring granuloma is characterized by a fibrinous ring surrounding a central fat vacuole. it has been found in the liver and bone marrow of patients with q fever, and occasionally with visceral leishmaniasis, cytomegalovirus, epstein-barr virus, staphylococcus epidermidis infections, hodgkin's lymphoma, and hypersensitivity to allopurinol. we describe a case of serologically confirmed viral hepatitis a with this lesion in the liver biopsy. a false positive anti-hepatitis a virus igm result h ... | 1992 | 1473440 |
| milk--a better drink? relationships with total serum cholesterol in a cross-sectional survey. the nordland health study. | cross-sectional studies have not consistently shown a positive association between milk drinking and serum cholesterol. we studied this relationship in a cohort of 7506 men and women aged 40-42 years in the county of nordland in northern norway (72% of all subjects in the age-bracket living in the county). we found a positive relationship between the percentage of fat in the milk and total serum cholesterol, but no positive relationship between whole fat milk consumption (number of glasses per d ... | 2006 | 1475646 |
| increased concentration of plasma cholesteryl ester transfer protein in nephrotic syndrome: role in dyslipidemia. | hyperlipidemia is a prominent feature of the nephrotic syndrome. lipoprotein abnormalities include increased very low and low density lipoprotein (vldl and ldl) cholesterol and variable reductions in high density lipoprotein (hdl) cholesterol. we hypothesized that plasma cholesteryl ester transfer protein (cetp), which influences the distribution of cholesteryl esters among the lipoproteins, might contribute to lipoprotein abnormalities in nephrotic syndrome. plasma cetp, apolipoprotein and lipo ... | 1992 | 1479291 |
| [autonomic function and severity of hypertrophic cardiomyopathy by power spectrum analysis on heart rate variability]. | to examine the relation of autonomic function and severity of hypertrophic cardiomyopathy (hcm) with and without ventricular tachycardia (vt) and poor blood pressure response on treadmill exercise, 30 patients with hcm and 10 healthy controls were selected. autonomic function was assessed by heart rate variability (hrv) on 24hr-holter monitoring. the power spectrum analysis was classified into lf component, hf component and ratio of lf/hf. (1) night time hf and lf decreased, and lf/hf increased ... | 1990 | 1480833 |
| diabetic amyotrophy in a teenage boy. | 1991 | 1481312 | |
| performance appraisal of online medline access routes. | to compare the performance and cost of 11 online medline systems with medline at elhill. | 2006 | 1482922 |
| chartline: providing bibliographic references relevant to patient charts using the umls metathesaurus knowledge sources. | a successful medical informatics program helps its users to match their information needs as closely and efficiently as possible to the capabilities of the system. chartline is a computer program whose input is a free text, "natural language" patient chart in ascii format. using the umls metathesaurus knowledge sources, chartline can suggest bibliographic references relevant to the patient case described in the chart. the program does not attempt to "understand" the natural language content of t ... | 2006 | 1483014 |
| watching a generation die: canadian doctors and the battlefields of world war i. | 2006 | 1483240 | |
| [q fever and endocarditis. apropos a new case]. | endocarditis is the first manifestation of q fever in its chronic form, generally affecting prosthetic cardiac valves or previously injured valves. its clinical presentation is an endocarditis with negative culture and there is not agreement with regard to the most adequate antimicrobial treatment and its duration. frequently, the valve has to be replaced. we present a case of a patient with double aortic lesion, in whom endocarditis by q fever was diagnosed and treated with doxycycline, initial ... | 1992 | 1486170 |
| [q fever and anticardiolipin antibodies]. | 1992 | 1488525 | |
| twinning and the r/k reproductive strategy: a critique of rushton's theory. | the theory of r selection, favoring population growth, as opposed to k selection, favoring more efficient utilization of resources, has in recent years been applied by rushton to contrast human ethnic groups in terms of their r/k reproductive strategies, suggesting the existence of a continuum from r groups, producing many offspring but providing little parental care, to k groups, producing few offspring but providing much parental care. rushton's theory, which is largely based on ethnic differe ... | 1992 | 1488860 |
| do no harm. | 2006 | 1489408 | |
| anterior chamber lens exchange. | 2006 | 1489455 | |
| updated evaluation of the activity of antibiotics in a burn centre. | the results of microbiological tests performed in a burns unit between january 1989 and december 1990 have been analysed. burn wound swabs and biopsies, blood cultures, central venous and urinary catheters, bronchial aspirates, pharyngeal swabs and faecal cultures for a total of 7950 examinations were considered. staph. aureus was the most frequently isolated bacterium, followed by staph. epidermidis, pseud. aeruginosa and e. coli. the antibiograms have shown a low efficacy rate of cephalosporin ... | 2006 | 1489502 |
| cement water--the hidden hazard. | 2006 | 1489505 | |
| characterization of the specificity of the human antibody response to the v3 neutralization domain of hiv-1. | the major neutralization domain of hiv-1, contained in the third variable region (v3) of the external envelope, is highly variable at positions flanking a conserved glycine-proline-glycine sequence. we investigated the relation between v3 sequences of hiv-1 variants circulating in a host and that host's antibody specificity. multiple v3 sequences were obtained directly, via pcr and subsequent cloning, from serum rna or cellular dna from 26 individuals (from 12 around seroconversion). then, speci ... | 1992 | 1489578 |
| individual somatotopy of primary sensorimotor cortex revealed by intermodal matching of meg, pet, and mri. | a method for comparing estimated magnetoencephalographic (meg) dipole localizations with regional cerebral blood flow (rcbf) activation areas is presented. this approach utilizes individual intermodal matching of meg data, of rcbf measurements with [15o]-butanol and positron emission tomography (pet), and of anatomical information obtained from magnetic resonance (mr) images. the meg data and the rcbf measurements were recorded in a healthy subject during right-sided simple voluntary movements o ... | 2006 | 1489648 |
| resigned on pay but not on prescribing. | 2006 | 1489698 | |
| proceedings of the stromberg (mainz, germany) meeting of the society for research into hydrocephalus and spina bifida, 1992. | 2006 | 1489736 | |
| [lower respiratory infection caused by coxiella burnetti in children]. | 1992 | 1489786 | |
| [granulomatous hepatitis and pericarditis caused by q fever]. | 1992 | 1489807 | |
| improved procedure for the drying and storage of polyacrylamide slab gels. | an improved procedure for the drying and storage of polyacrylamide (paa) slab gels of various sizes and acrylamide contents is presented. a paa slab gel is preferentially fixed in methanol-acetic acid-glycerol-water (1.0:1.0:0.1:2.0) and then dried under low pressure in an adapted photoprint dryer between cellophane and polyethylene foils at 75-80 degrees c for 50-90 min. strong, transparent and flexible sheets are obtained that can be stored for extended periods. the potential of the procedure ... | 1992 | 1491050 |
| [q fever: epidemic outbreak of the pure febrile form]. | to describe an epidemic of 30 cases of q fever, none of which had respiratory manifestations. | 1992 | 1498234 |
| coxiella burnetii superoxide dismutase gene: cloning, sequencing, and expression in escherichia coli. | a superoxide dismutase (sod) gene from the obligate intracellular bacterium coxiella burnetii has been cloned, and its dna sequence has been determined and expressed in escherichia coli. the gene was identified on psjr50, a phc79-derived genomic clone, by using the polymerase chain reaction with degenerate oligonucleotide primers corresponding to conserved regions of known sods. sequences resembling conventional e. coli ribosomal and rna polymerase-binding sites preceded the c. burnetii 579-bp s ... | 1992 | 1500190 |
| primary humoral antibody response to coxiella burnetii, the causative agent of q fever. | of 147 patients with acute q fever diagnosed during a major outbreak in birmingham, england, in early summer 1989, 41 provided sets of sera which allowed us to make a detailed analysis of the primary humoral immune response. antibody titers specific for coxiella burnetii were measured by the complement fixation test and by an immunoglobulin m (igm)- and igg-specific indirect immunofluorescence test. the relative avidity of specific iggs was determined by the indirect immunofluorescence test with ... | 1992 | 1500499 |
| [recurrent pericarditis caused by q fever]. | 1992 | 1502412 | |
| electron-microscopic study of the effect of various extractants on the morphology of coxiella burnetii. | this paper presents the results of the effect of trichloroacetic acid (tca) at two different temperatures and the effect of a mixture of detergents (d) on coxiella burnetii. both tca and d caused a large destruction of c. burnetii cells. in both cases complexes of high-molar-mass components from the outer membrane were extracted. in the d case not only proteins but a mixture with other high-molar-mass structures were released from the destroyed cells. by extraction of tca, the antigenic complex ... | 1992 | 1505876 |
| [the hepatic form of q fever]. | 1992 | 1520558 | |
| coxiella burneti endocarditis in a patient with positive chlamydial serology. | a 41-year-old man who habitually slept in a car park presented with a culture-negative endocarditis. serological tests indicated infection with both coxiella burneti and chlamydia psittaci. he was treated with doxycycline and clindamycin and required aortic valve replacement. culture of the excised value for both agents was negative but electron microscopy was suggestive of coxiella endocarditis. | 1992 | 1522334 |
| [q fever antibody titer--follow-up study in cattle with special reference to pregnancy]. | in 290 q fever positive cattle from three 2000 head dairy farms in the former district of erfurt (thüringen) the course of titers was examined serologically over several months by means of the complement fixation test (cft). in 47.2% of the cows serologically observed for 2 up to 28 months complement fixing antibodies against coxiella burnetii could be demonstrated til the end of the investigation period. repeated tests during pregnancy showed increase of antibody titers in the first 4 months an ... | 1992 | 1524578 |
| carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i. | the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ... | 2006 | 1525184 |
| the influence of autonomic failure on plasma anf concentration in uremic patients on chronic hemodialysis. | we compared plasma anf concentration in 5 diabetic-uremics with combined sympathetic-parasympathetic dysfunction with that in 9 uremic patients without autonomic impairment. symptomatic dialysis hypotension was a major clinical problem in all diabetic-uremics. in the volume-expanded state, anf was almost twice as high (p less than 0.025) in diabetic-uremics than in control uremics (152 +/- 29 vs 84 +/- 10 pg/ml) in the face of similar right atrial pressure (14 +/- 3 vs 12 +/- 1 cm h2o). after is ... | 2006 | 1533821 |
| [interesting pyp, 201tl, mibg, am and bmipp myocardial spect images in a patient under successful reperfusion therapy]. | various types of radiopharmacons such as 201tl, 99mtc-pyrophosphate(pyp), 123i-metaiodobenzyl-guanidine(mibg), 111in-antimyosin fab (am) and 123i-beta-methyl iodophenyl pentadecanoic acid (bmipp) were applied to a patient under successful reperfusion therapy. in the patient, elevated serum enzyme activity region in the subacute phase. ten months after the ischemic event, am uptake was noted at the region which maintained contractility. two years after the ischemic event, depressed bmipp uptake a ... | 1991 | 1535723 |
| influence of soil moisture and microbial activity on pendimethalin degradation. | 1980 | 1536999 | |
| modulation of phencyclidine-sensitive ethidium binding to the torpedo acetylcholine receptor: interaction of noncompetitive inhibitors with carbamylcholine and cobra alpha-toxin. | ethidium is one of two fluorescent ligands known to bind to the noncompetitive inhibitor (nci) site in the central ion channel of the torpedo acetylcholine receptor with a micromolar dissociation constant. to further characterize heterotropic allosteric regulation of ligand binding in general, and of ethidium binding in particular, to the torpedo receptor, we measured the effects of three liquid anesthetics (diethyl ether, halothane, and butanol), two barbiturates (secobarbital and thiamylal), a ... | 2006 | 1538711 |
| prophylaxis against non-steroidal induced upper gastrointestinal side effects. | 2006 | 1540028 | |
| modulation of macrophage hyperactivity improves survival in a burn-sepsis model. | macrophage hyperactivity with increased production of tumor necrosis factor, interleukin 6, interleukin 1, and prostaglandins has been demonstrated in the injured patient, but the effect of this on the clinical outcome is unclear. we studied the effect of combination interleukin 1 beta and indomethacin sodium therapy on macrophage hyperactivity and survival after sepsis in a murine burn model. macrophage interleukin 1, interleukin 6, and tumor necrosis factor alpha production were all significan ... | 1992 | 1540091 |
| review of breast cancer screening guidelines. | 2006 | 1544090 | |
| chronic coxiella burnetii infection mimicking malignant hematologic disease. | 1992 | 1553961 | |
| polyorchidism: functional classification and management strategy. | polyorchidism is rare. we report a recent case and review the literature. a simple classification based on anatomic and functional arrangements of the testes and their drainage systems is described. combining this classification with a knowledge of potential complications, we propose a management strategy. | 2006 | 1557854 |
| [new possibilities for the diagnosis of q fever and for the differentiation of the causative agent]. | the current diagnostic procedures for q fever are discussed, especially isolation and propagation of coxiella burnetii in bgm cell cultures, detection of antigen by an enzyme immunoassay using a biotinylated monoclonal antibody and the polymerase chain reaction (pcr). the latter is of special importance for differentiation of isolates. | 1992 | 1558529 |
| [why do physicians and patients ever more often resort to practitioners of alternative medicine: the healer and the quack?]. | 2006 | 1563606 | |
| fine-needle aspiration findings of the liver in a case of q fever. | this report describes the cytologic findings in q fever involving the liver in a 59-yr-old man. the fine-needle aspiration findings are correlated with a surgical needle biopsy performed concurrently. cytopathologists should include q fever in their differential diagnosis of granulomatous inflammation. ring granulomas, which can be seen in an aspiration biopsy, should suggest the diagnosis of q fever. | 1992 | 1568415 |
| b-cell factor 1 is required for optimal expression of the dra promoter in b cells. | the x box in the dra promoter of the human histocompatibility complex is required for expression of the dra gene in b cells. we show that a b-cell factor binds to a sequence that is clearly distinguishable from binding sites for the previously described x box binding nuclear proteins rf-x, nf-x, nf-xc, nf-s, hxbp, and ap-1. mutations in the dra x box that disrupt the binding of this factor result in a lower level of gene expression, as does the presence of id (a trans-dominant regulatory protein ... | 1992 | 1569956 |