Publications

TitleAbstractYear
Filter
PMID(sorted ascending)
Filter
dietary habits, sexual maturation, and plasma hormones in pubertal girls: a longitudinal study.the relationships between dietary components and physical or hormonal sexual maturation in 63 pubertal girls were examined. the effects of vegetable protein and dietary fiber on breast development (b = -2.0, p less than 0.05; b = -2.6, p less than 0.05, respectively) became more pronounced in a multivariate analysis, after elimination of the linear effects of body height and energy intake. from the multivariate analysis with combinations of vegetable protein, polysaccharides, and fiber in the eq ...20071951150
structure-activity relationship of yohimbine and its related analogs in blocking alpha-1 and alpha-2 adrenoceptors: a comparative study of cardiovascular activities.we investigated the selectivities and structure requirements for alpha-1 and alpha-2 adrenoceptor blocking activities of yohimbine (yo) and its 12 related analogs, such as beta-yohimbine (beta-yo), dihydrocorynantheine (dhc) and (-)indoloquinolizidine ((-)iq). the affinity of yo analogs to alpha-adrenoceptor was assessed by measuring their blockade of pressor responses to epinephrine in pithed rats. among yo structure groups, the potency order was yo greater than dhc = beta-yo greater than geiss ...19901976443
pioneer neurons and target selection in cerebral cortical development. 20051983445
pioneer neurons and target selection in cerebral cortical development. 20051983445
a case of vibrio vulnificus septicaemia acquired in victoria.the clinical features and laboratory findings of a case of vibrio vulnificus septicaemia are reported. the illness occurred in a previously well 68-year-old man who was accidentally spiked in the buttock by the dorsal spine of a flathead caught in tamboon inlet, near mallacoota, victoria. the clinical picture of an acute septicaemic illness with shock, associated with metastatic cellulitic lesions on the lower limbs progressing to bulla formation, skin necrosis, necrotising fasciitis and myositi ...19911988798
pulmonary infiltrates associated with vibrio vulnificus septicemia.in the case described, fatal vibrio vulnificus primary septicemia was complicated by development of diffuse pulmonary infiltrates. clinical features of this recently discovered infectious disease are discussed. various aspects of diagnoses of pulmonary infiltrates in patients with v vulnificus septicemia are also presented. vibriosis should be suspected in patients with chronic, underlying, predisposing diseases, recent ingestion of raw seafood, and characteristic skin lesions.19911997461
purification and characterization of a secreted protease from the pathogenic marine bacterium vibrio anguillarum.vibrio anguillarum is a pathogenic marine bacterium which causes the disease vibriosis in salmonid fish, which is characterized by a fatal hemorrhagic septicemia accompanied by massive tissue destruction. in this paper, the purification of the major caseinolytic extracellular protease from v. anguillarum is presented. the purification steps include ammonium sulfate precipitation, deae-sepharose chromatography, sephacryl s-200 chromatography, and deae high-pressure liquid chromatography. the puri ...19912012804
ozone depuration of vibrio vulnificus from the southern quahog clam, mercenaria campechiensis.southern quahog clams, mercenaria campechiensis, were dosed with vibrio vulnificus and placed in a pilot-scale depuration system using ozonated recirculated artificial seawater. twenty-four hours of treatment with ozone-treated recirculating artificial seawater reduced the numbers of v. vulnificus in the shellfish meats by an average of 2 log units when compared to natural die-off in control clams. the oxidant levels (up to 3 mg/liter) did not adversely affect shellfish pumping during the depura ...19912022868
polymerase chain reaction identification of vibrio vulnificus in artificially contaminated oysters.dnas extracted from vibrio vulnificus seeded into oyster homogenates were evaluated as templates for the polymerase chain reaction. several extraction procedures were examined, and it was determined that dna recovered from cells lysed by guanidine isothiocyanate, extracted with chloroform, and precipitated with ethanol was most suitable for use as a polymerase chain reaction template. the region targeted was a 519-bp portion of the cytotoxin-hemolysin gene of v. vulnificus. this region was ampli ...19912039231
ovarian cancer. 20072042058
coronary reserve in patients with aortic valve disease before and after successful aortic valve replacement.in patients with aortic valve disease and normal coronary angiograms coronary reserve was determined by the coronary sinus thermodilution technique. three groups of patients were studied: 37 preoperative patients; 18 different patients 12-52 months after aortic valve replacement and seven control subjects with no cardiac disease. coronary flow ratio (dipyridamole/rest) was diminished in preoperative compared with postoperative patients (1.66 +/- 0.44 vs 2.22 +/- 0.85; p less than 0.05) as well a ...20072044545
glucagon and clonidine testing in the diagnosis of pheochromocytoma.we assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor. in the glucagon stimulation test, blood was sampled 2 minutes after intravenous injection of 0.28 mumol (1 mg) glucagon, and in the clonidine suppression test, blood was sampled 3 hours after administration of oral clonidine, 1.30 mumol (0.3 mg)/70 kg body wt. baseline levels of catechols in antecu ...20072045133
zambia: focus on humanitarian care of aids patients. 20072045228
no time for an aids backlash. 20072045284
the economics of spaying and neutering: market forces and owners' values affecting pet population control. 19912045338
enzyme immunoassay for identification of vibrio vulnificus in seawater, sediment, and oysters.historically, methods used to identify vibrio vulnificus in environmental samples have been inadequate because isolation and identification procedures are time-consuming and fail to separate v. vulnificus from other bacterial species. we describe an enzyme immunoassay (eia) and culture techniques which identified v. vulnificus in seawater, sediment, and oysters. the eia used monoclonal antibody frbt37 to a species-specific epitope of v. vulnificus. no cross-reactions were observed among 72 non-v ...19912059045
vibrio vulnificus septicemia in korea: clinical and epidemiologic findings in seventy patients.we studied the clinical characteristics and the epidemiology of primary septicemia associated with vibrio vulnificus in 70 patients. all patients came from the western and southern coastal areas of korea. most cases (96%) occurred during the summer months, in men (96%), and in persons 40 or more years of age (90%). the illness of 46 patients (66%) began with septicemia, often within 2 days of the consumption of raw seafood. forty-seven patients (67%) had preexisting hepatic disease, and 49 (70%) ...19912061435
electrophoretic analysis of lipopolysaccharide isolated from opaque and translucent colony variants of vibrio vulnificus using various extraction methods.lipopolysaccharides (lps) from an opaque and a translucent colony variant of vibrio vulnificus were isolated by several methods and the electrophoretic profiles were analysed. the phenol-water extraction method provided a better yield compared to the phenol-chloroform-petroleum ether method. in addition, two rapid micro-assays were used to isolate lps for electrophoretic analysis. the electrophoretic pattern was the same for all lps extracts and was similar in both variants. no high molecular we ...19912062249
oysters, iron overload and vibrio vulnificus septicaemia.a case of vibrio vulnificus septicaemia complicated by cutaneous leg ulceration is described. a 74 year old man with haemochromatosis and sideroblastic anaemia developed an acute febrile illness with cutaneous manifestations 24 hours after ingesting raw oysters. the presence of blistering should be considered an important clue to the diagnosis of vibrio vulnificus septicaemia, and this can facilitate prompt effective antimicrobial therapy. clinicians should be aware of this infection because of ...19902073206
scalp cooling by cold air for the prevention of chemotherapy-induced alopecia.a new system is described for cooling the scalp with cold air in order to prevent chemotherapy-induced alopecia. compressed air was cooled by means of a vortex tube built into a hair-drier cap. this system reduced the blood flow in the scalp to 35%, the surface temperature to 14.2 degrees c and the intradermal temperature at hair follicle level to 29.2 degrees c. the low temperature could be kept constant for at least one hour of cooling. by means of comparison, with cryogel packs the lowest epi ...20072074916
[a juvenile form of osteochondrosis]. 20072074966
enhancement of virulence of two environmental strains of vibrio vulnificus after passage through mice.the virulence of two environmental strains of vibrio vulnificus to iron-loaded adult mice was enhanced by passage through mice. estimates of 50% lethal dose values (ld50) determined by end point titration were reduced 100- and 1000-fold for the two strains. passage through mice also selected for the opaque colony type phase variation of v. vulnificus, reported by others to be more virulent to mice than a translucent colony type.19902076589
[experiences in incidence monitoring and control of the pharaoh ant in a health resort].today monomorium pharaonis still represents a threat of the hygiene regime in the objects of public health and welfare, particularly for the asepsis and the "black-white-separation". the experiences collected throughout a successful rub out by the preparate "lafarex n 87" in a health-resort are presented. the necessity of cooperation of all concerned persons (owners, pest control enterprises and public hygiene service) are emphasized.20052095048
[the significance of the determination of catecholamines and their metabolites in neuroblastomas].a method for the determination of catecholamines and their metabolites in the urine was established. the specimens were previously cleaned by ion exchangers and the components were separated by a 'reversed phase' ionic pair chromatography, determined by an electrochemical 'wall-jet'-detector. this method was applied in order to find a diagnostic marker in case of neuroblastoma diseases. in 85 per cent of the patients (n = 13) we stated an increased ejection of dopamine.20062095056
[derivative spectroscopy and its use in sanitary hygiene control].an analytical method is developed for defining the residual quantities of rodenticide "brodifacoum" (talon) used in the control of harmful field rodents and especially for species microtus. the method is based on extracting the pesticide with chloroform and making use of spectrophotometry in the ultraviolet field in intervals 340-240 nm. the second derivative of the absorption is utilized as well as the band with maximum 288 nm and minimum 228 nm. the peak height in this interval is in proportio ...20072099444
permeability-enhancing action of vibrio vulnificus protease and its control system. 19902101153
[avoid errors. preparation of abutments for removable denture cast framework]. 20072151674
phenotypic evaluation of acapsular transposon mutants of vibrio vulnificus.translucent, avirulent spontaneous phase variants of vibrio vulnificus mo6-24 reverted back to the original opaque, encapsulated phenotype under both in vivo and in vitro conditions. two translucent, acapsular mutants, which did not show phase variation, were constructed by using the transposon tn5 is50l::phoa (tnphoa). loss of capsule was accompanied by decreases in virulence, hydrophilicity, and serum resistance. the ability to utilize transferrin-bound iron for growth was lost in only one of ...19902160432
[the diagnostic value of mr tomography following gadolinium-dtpa compared to computed tomography in bladder tumors].in a prospective study, 58 patients with carcinomas of the bladder were examined by ct and mri; in 48, gadolinium-dtpa was administered intravenously. mri provided exact staging in 89%, compared with 80% with ct. there was 13% over-staging with ct and 11% with mri. mri, unlike ct did not result in any under-staging. in 36 patients a quotient could be calculated from the signal intensity of the tumour and surrounding soft tissues both before and after the intravenous contrast medium and the incre ...20072168077
kinetics of the reaction of prostaglandin h synthase compound ii with ascorbic acid.the reduction of prostaglandin h synthase compound ii by ascorbic acid in the presence of diethyldithiocarbamate was studied in 0.1 m phosphate buffer (ph 8.0) at 4.0 +/- 0.5 degrees c, by rapid scan spectrometry and transient state kinetics. a saturation effect and nonzero intercept were observed in the plot of pseudo-first-order rate constant versus ascorbic acid concentration. the saturation behavior suggests formation of a complex between prostaglandin h synthase compound ii and ascorbic aci ...19902168160
local control of operable breast cancer after radiotherapy alone.221 patients with operable breast carcinoma stage tis, t1, t2, t3, n0n1 were treated with radiotherapy alone without tumorectomy. the mean follow-up time was 15.5 years (range 5-22). the annual risk for local recurrence was 3% during the first 5 years and 1% during the following 10 years, resulting in an actuarial local control rate of 75.4% after 15 years. the risk for local recurrence was assessed in multivariate analysis and was significantly related to the size of the tumour measured on mamm ...20072168190
characterization of two low em forms of cytochrome a3 and their carbon monoxide complexes in mammalian cytochrome c oxidase.evidence is presented for the existence of two forms of low-potential cytochrome a3. one appears to be similar to the low-spin form reported by nicholls, p., and v. hildebrandt (1978 biochem. j. 173:65-72) and wrigglesworth, j. m., j. elsden, a. chapman, n. van der water, and m. f. grahn (1988. biochim. biophys. acta. 936:452-464). it has a reduced soret peak near 428 nm and a prominent alpha peak near 602 nm. this form is seen when the enzyme is either supplemented with lipoprotein or incorpora ...19902168220
[methods of determining clinically sufficient decurarization and its evaluation].mechanomyoscopy as an objective method for determining the degree of decurarisation is particularly useful in the case of uncooperative patients and those who are incapable of adequate neck flexion mostly for spinal column diseases. the authors use for that purpose a czechoslovak-made neuromuscular stimulator (lsn 110), with constant 50 hz frequency of stimulation, 0.3 ms impulse duration, max. 50 ma and, depending on skin impedance, 5-140 v. the stimulator switch is manually controlled. the abs ...20072168290
role of oxygen free radical formation in the mechanism of menogaril resistance in multidrug resistant tumor cells.the mechanisms of action and resistance to menogaril, a clinically active anthracycline antitumor drug, were evaluated in sensitive and doxorubicin-selected multidrug resistant human breast tumor (mcf-7) cell lines. while mcf-7/adrr cells were highly resistant (250-500-fold) to doxorubicin, they displayed only marginal resistance (10-fold) to menogaril. in contrast to doxorubicin, the mechanism of resistance to menogaril in these cells does not involve differential inhibition of dna synthesis as ...19902168296
the antiphospholipid antibody dilemma. 20072168305
somatostatin receptor incidence and distribution in breast cancer using receptor autoradiography: relationship to egf receptors.somatostatin receptors (ss-r) were measured with in vitro receptor autoradiography using the ss analog 125i-[tyr3]-sms 201-995 as radioligand in 342 breast-tumor samples. in a group of 158 "small" tumor samples (mean section surface: 14 mm2 +/- 0.4; mean +/- sem), 34 tumors (21%) were ss-r positive. in a group of 72 "large" tumor samples (mean size: 180 mm2 +/- 8; mean +/- sem), 33 tumors (46%) were ss-r positive. in this second group, more than half of the tumors had a non-homogeneous distribut ...20072168344
[the topographic anatomical basis for ventriculosinusal shunting in hydrocephalus in nursing and young infants].the peculiarities in the structure and topographic anatomical relations of the superior longitudinal, lateral, and sigmoid sinuses were studied on block preparations of the posterior cranial fossa of 14 children under 3 years of age who died from somatic diseases. it was shown that intrasinus inclusions preventing catheterization of the sinus (bands and septa) were absent at the junction of the first angle of the sigmoid sinus with its descending part. the authors recommend this area for shuntin ...20072168650
mechanisms underlying the stimulation of pth release by gppnhp in permeabilized bovine parathyroid cells.we examined changes in camp and inositol phosphate metabolism to assess the contribution of the guanine nucleotide regulatory (g) protein(s) regulating adenylate cyclase and phospholipase c in mediating the stimulatory effects of gppnhp on pth release from permeabilized bovine parathyroid cells. to examine the role of gs, the g protein stimulating adenylate cyclase, and camp on pth release, permeabilized cells were incubated with either gppnhp or isoproterenol, and the effects of these agents on ...19902168660
proton-nuclear magnetic resonance relaxation times in brain edema.proton relaxation times of protein solutions, bovine brain, and edematous feline brain tissue were studied as a function of water concentration, protein concentration, and temperature. in accordance with the fast proton exchange model for relaxation, a linear relation could be established between r1 and the inverse of the weight fraction of tissue water. this relation also applied to r2 of gray matter and of protein solutions. no straightforward relation with water content was found for r2 of wh ...19902168666
[amalgam discussion. question of amalgam toxicity and allergy]. 20072171028
[a case of fatal sepsis due to vibrio vulnificus].a 66-year-old male with chronic alcoholic liver injury was admitted on july 27, 1986 to our hospital with complaints of high fever, convulsion and skin erythema. he had consumed raw fish 3 days before, and had a scratch wound over the right arm and left leg because he had slipped in a small stream in the woods the day before admission. he was already in shock state with sepsis of v. vulnificus and dic on admission. although the treatment with abpc, cp, caz, mino for sepsis, and heparin & antithr ...19902187037
in vitro activity of ljc10,627, a new carbapenem antibiotic with high stability to dehydropeptidase i.the in vitro activity of ljc10,627, a new carbapenem, was compared with those of imipenem and ceftazidime. ljc10,627 had broad-spectrum activity against gram-positive and gram-negative clinical isolates. the mics of this compound for 90% of members of the family enterobacteriaceae tested (mic90s), including strains resistant to ceftazidime, ranged from 0.1 to 25 micrograms/ml. ljc10,627 inhibited pseudomonas aeruginosa at an mic90 of 3.13 micrograms/ml; it thus was twofold more active than imipe ...19902203313
personal power: your key to success. 20072216083
determination of the affinity of a steroid for its receptor is not sufficient to measure its intrinsic hormonal activity. 20072219201
determination of the affinity of a steroid for its receptor is not sufficient to measure its intrinsic hormonal activity. 20072219201
massive rhabdomyolysis: a rare presentation of primary vibrio vulnificus septicemia. 19902220890
[lung cancer in women in moscow (epidemiology, etiology and surgical treatment)].in the studied period (1973-1987) the lung carcinoma morbidity rate among females of moscow, in general intensive indices (per 100,000 females), showed a tendency to reduce (18.4 in 1973 and 15.1 in 1987). a reverse tendency is mostly encountered in other countries. more than half of patients with lung carcinoma were over 70 years of age. the ratio of males with lung carcinoma to that of females grew from 3.0:1.0 in 1973-1977 to 3.6:1.0 in 1983-1987. in the period from 1979 to 1988, 380 females ...20072223213
[lung cancer in women in moscow (epidemiology, etiology and surgical treatment)].in the studied period (1973-1987) the lung carcinoma morbidity rate among females of moscow, in general intensive indices (per 100,000 females), showed a tendency to reduce (18.4 in 1973 and 15.1 in 1987). a reverse tendency is mostly encountered in other countries. more than half of patients with lung carcinoma were over 70 years of age. the ratio of males with lung carcinoma to that of females grew from 3.0:1.0 in 1973-1977 to 3.6:1.0 in 1983-1987. in the period from 1979 to 1988, 380 females ...20072223213
[the importance of the compensatory powers of the lungs in determining the indications for surgical treatment of hypoplasia of the lungs].the author studied the compensatory possibilities of pulmonary respiration, gas exchange and hemodynamics of pulmonary circulation to determine the indications for operative treatment of simple hypoplasia of the lungs. the work is based on the results of examination of 58 patients. forty-five patients underwent an operation. it was established that simple hypoplasia of the lungs is characterized by mild ventilation disorders and deep disorders of gas exchange leading to manifest and latent hypox ...20072223215
[the importance of the compensatory powers of the lungs in determining the indications for surgical treatment of hypoplasia of the lungs].the author studied the compensatory possibilities of pulmonary respiration, gas exchange and hemodynamics of pulmonary circulation to determine the indications for operative treatment of simple hypoplasia of the lungs. the work is based on the results of examination of 58 patients. forty-five patients underwent an operation. it was established that simple hypoplasia of the lungs is characterized by mild ventilation disorders and deep disorders of gas exchange leading to manifest and latent hypox ...20072223215
[a congenital esophagotracheal fistula in an adult]. 20072223222
[a congenital esophagotracheal fistula in an adult]. 20072223222
[diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart].the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ...20072223226
[diagnosis and surgical treatment of traumatic damage to the sinus of valsalva following penetrating wounds of the heart].the authors had three patients with traumatic damage of the sinus of valsalva, caused by penetrating injury of the thorax inflicted with a knife. the patients were brought to the clinic in a grave condition with decompensation of systemic and pulmonary circulation. the anomaly called for emergency surgical correction under conditions of extracorporeal circulation. the diagnosis was based on the complaints, medical history, clinical picture, the results of functional methods of examination includ ...20072223226
fluorosis, osteopetrosis, and ectopic calcification. 20072223455
fluorosis, osteopetrosis, and ectopic calcification. 20072223455
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
[growth and therapy in angle class ii/2--a longitudinal cephalometric study].the influence of both growth and functional therapy with the u-bow-activator type i on angle class ii subdivision 2 malocclusion is analysed in a cephalometric long term study. findings concerning skeletal problems: 1. therapeutically intended clockwise rotation of the mandible with vertically and sagittally controlled maxillary position, 2. achieving normal sagittal mandibular growth rates. dental problems are improved significantly. the results obtained by functional therapy and growth proved ...20072227736
[growth and therapy in angle class ii/2--a longitudinal cephalometric study].the influence of both growth and functional therapy with the u-bow-activator type i on angle class ii subdivision 2 malocclusion is analysed in a cephalometric long term study. findings concerning skeletal problems: 1. therapeutically intended clockwise rotation of the mandible with vertically and sagittally controlled maxillary position, 2. achieving normal sagittal mandibular growth rates. dental problems are improved significantly. the results obtained by functional therapy and growth proved ...20072227736
[initial attitudes to orthodontic treatment--the results of a practical and clinical questionnaire study (i)].312 patients from one clinic and nine offices, between eight and 15 years of age treated with bionators, their parents and a control group were questioned on various aspects of their treatment. findings regarding opinions about dentofacial appearance, initial motives and expectations are presented. aesthetic motives proved preponderant by seeking treatment though the children's ability to verbally differentiate aesthetic concepts was poor. above all, they expected visible treatment progress, abs ...20072227739
[initial attitudes to orthodontic treatment--the results of a practical and clinical questionnaire study (i)].312 patients from one clinic and nine offices, between eight and 15 years of age treated with bionators, their parents and a control group were questioned on various aspects of their treatment. findings regarding opinions about dentofacial appearance, initial motives and expectations are presented. aesthetic motives proved preponderant by seeking treatment though the children's ability to verbally differentiate aesthetic concepts was poor. above all, they expected visible treatment progress, abs ...20072227739
abelson murine leukemia virus transforms preneoplastic emu-myc transgene-carrying cells of the b-lymphocyte lineage into plasmablastic tumors.e mu-myc transgenic mice were back-crossed to balb/c mice up to back-cross generation 3. the offspring that included transgene-carrying and -negative mice in approximately equal proportions were randomly divided into 2 groups. thirty-four mice (group i) were treated with pristane, followed by a-mulv, and 40 (group ii) were injected with a-mulv alone. altogether, 16 lymphoid tumors developed in group i and 17 in group ii. nine of the tumors in group i and 4 in group ii appeared as ascitic tumors. ...19902228313
resuscitation of patients with cardiac arrest by ambulance staff with extended training in west yorkshire.to investigate the results of resuscitation of patients with cardiac arrest by ambulance staff with extended training in west yorkshire.20062242460
[focal liver lesions as incidental findings. 2: diagnostic procedures in sonographically homogeneous echo-rich, echo-poor or inhomogeneous lesions].hemangioma is one of the most common incidental findings in the ultrasonographic image. in 80% to 90% of the cases, the hemangioma presents as a homogeneous lesion in the us image. in asymptomatic patients and a lesion diameter of less than 2 cm, further clarification additional to ultrasonography is not necessary. major differential diagnoses are focal nodular hyperplasia, metastasis, hepatocellular carcinoma and liver cell adenoma. with exceptions, the biological significance of echo-poor or i ...20082242838
neonatal monosodium glutamate abolishes corticotropin-releasing factor-induced epileptogenic activity in rats.intracerebroventricular (i.c.v.) injection of rat corticotropin-releasing factor (rcrf) at doses of 5-20 micrograms in rats induces epileptogenic activity characterized by pacemaker-like spikes localized in the hippocampal leads. such an effect was still present in rats neonatally treated with saline but was absent in those neonatally treated with monosodium glutamate (msg), a treatment that caused marked changes in the concentration of several brain neurotransmitters and neuropeptides in hypoth ...19902245800
neonatal monosodium glutamate abolishes corticotropin-releasing factor-induced epileptogenic activity in rats.intracerebroventricular (i.c.v.) injection of rat corticotropin-releasing factor (rcrf) at doses of 5-20 micrograms in rats induces epileptogenic activity characterized by pacemaker-like spikes localized in the hippocampal leads. such an effect was still present in rats neonatally treated with saline but was absent in those neonatally treated with monosodium glutamate (msg), a treatment that caused marked changes in the concentration of several brain neurotransmitters and neuropeptides in hypoth ...19902245800
[early and long-term results of percutaneous transluminal coronary angioplasty in angina pectoris]. 20072258666
[early and long-term results of percutaneous transluminal coronary angioplasty in angina pectoris]. 20072258666
[a training program after coronary surgery improves blood lipid profile]. 20082263103
tcnu in adenocarcinoma of the lung: a phase ii study with divided doses.tcnu, a new water soluble nitrosourea, has in preclinical studies shown higher activity when given as divided doses compared with one day single treatment. accordingly, 38 consecutive patients with non-resectable adenocarcinoma of the lung received tcnu 40 mg/m2 p.o. daily for three days every 4 weeks. the response rate among 37 evaluable patients was 14%, median response duration was 17 weeks (range 5-57+ weeks) and median survival 22 weeks (range 3-96+ weeks). hematologic toxicity was pronounc ...20082265139
age distribution of erythrocyte population in late pregnancy.the age population distribution of erythrocytes in late pregnancy was evaluated by the volume and density distribution of cells. this approach enables an evaluation of the life span of erythrocytes in the circulation without using radioactive elements. a younger cell population was found in the circulation of women in late pregnancy as compared to nonpregnant women of similar ages, which might be indicative of shortened life span of erythrocytes. this shortened life span might be explained by th ...20082265799
proteolytic processing of porcine big endothelin-1 catalyzed by cathepsin d.cathepsin d, a candidate for endothelin-converting enzyme (ece), was allowed to act on porcine big endothelin-1 (big et-1, 1-39). the proteinase primarily cleaved the asp18-ile19 and trp21-val22 bonds of big et-1(1-39), with a optimum ph of 3.5. the mature et-1(1-21), generated by the cleavage between trp21 and val22, was subsequently degraded by removal of most of the c-terminal tripeptide (ile19-ile20-trp21). therefore, cathepsin d is by no means a specific ece, although the proteinase does cl ...19902268325
fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism.1. fifteen patients received 1.5 g m-2 of ifosfamide intravenously over 0.5 h every day for 5 days. twenty-one courses of treatment were studied. plasma was assayed for ifosfamide by gas liquid chromatography and plasma alkylating activity was measured using the nitrobenzylpyridine (nbp) reaction. 2. a pharmacokinetic analysis revealed a significant decrease in the median (range) elimination half-life of ifosfamide from 7.2 (2.8-14.2) h on day 1 to 4.6 (2.3-7.7) h on day 5 (p less than 0.001, wi ...20082271371
a double-blind comparison of 0.5% bupivacaine and 0.75% ropivacaine administered epidurally in humans.in an attempt to compare equipotent doses of epidurally administered bupivacaine and ropivacaine, 44 healthy patients, aged 18-70 years, undergoing lower extremity orthopedic procedures were studied in a randomized, double-blind manner. twenty-one patients received a single epidural injection of 20 ml 0.5% bupivacaine at the l23 or l34 interspace and 23 patients received 20 ml 0.75% ropivacaine in a similar manner. onset of and recovery from sensory anesthesia and motor block were recorded. no s ...19902271468
tuberculous meningitis. 23 cases from a 12-year period (1976-1987).twenty-three patients with tuberculous meningitis were reviewed to see whether clinical features or initial laboratory findings could discriminate between these patients and other patients with bacterial meningitis. nineteen patients were danes and four immigrants. preexisting diseases were found in eight cases. duration of symptoms could be related to neurological sequelae, but not to death. the initial clinical picture was indistinguishable from meningitis of other causes. microscopy of the ce ...19922272213
a successfully treated case of vibrio vulnificus septicemia with shock.vibrio vulnificus infection often causes serious or fatal disease. recently, in japan there have been numerous reports of vibrio vulnificus infection. here, we report a successfully treated case of vibrio vulnificus septicemia with shock, disseminated intravascular coagulation (dic) and necrotizing cellulitis in a middle-aged heavy drinker with chronic alcoholic liver disease. on reviewing 38 cases in japan including ours, the overall mortality rate was 68%. although the incidence is relatively ...19902273613
incidence of vibrio vulnificus in northern new england water and shellfish.vibrio vulnificus, an autochthonous inhabitant of the estuarine environment, was detected in water and oysters from the great bay estuary system of new hampshire and maine. previously, it had not been detected north of boston harbor on the east coast of the united states. v. vulnificus was detected in water and shellfish samples at five out of ten sites, and only in areas that were not open to recreational shellfishing. although samples were collected from may into december, v. vulnificus was on ...19902283033
[bronchial hyperresponsiveness to histamine in guinea pig induced by intravenous administration of platelet activating factor].platelet activating factor (paf) has recently been demonstrated to play an important role in allergic diseases such as bronchial asthma. changes in airway wall thickness have recently been suggested to cause excess airway narrowing of asthma. in this study, the authors examined the bronchial hyperresponsiveness to histamine in guinea pig induced by intravenous administration of paf by measuring dynamic compliance and dynamic respiratory resistance. moreover, a new formula which can exclude the e ...19902290229
hepatitis b surface antigen seroconversion in resident doctors. 20082292578
generation of affinity for antithrombin iii by supplemental sulfation of heparin species with low affinity for the protein.the tributylammonium salt of a porcine heparin subfraction with low affinity for antithrombin iii (mr 7,500-18,000; anti-clotting activity, 7 usp units/mg), having degrees of sulfate substitution at d-glucosamine and l-iduronic acid residues of glcns 0.786, glcn6s 0.628, and idoa2s 0.682 mol, was reacted with 10 or 20 mol of pyridine-sulfur trioxide per mol equiv. of available hydroxyl groups in n,n-dimethylformamide at -10 degrees c for 1 h. both chemical and nmr spectroscopic analyses revealed ...19902292586
[regional blood lactate level in arterial occlusive diseases].fifty-seven patients with obliterating diseases of the lower limb arteries were examined. the concentration of lactate in the venous blood and the venous-arterial difference in the blood lactate level in the affected limb were found to be increased. a relationship between the marked character of these shifts and the severity of the ischemic syndrome was noted. the authors discuss the possibility of using the values of the lactate content in the regional blood as criteria for evaluating the effic ...20082292851
[a case of asymptomatic course of kidney tumor]. 20082292876
[technical problems of various sanitary-hygienic aspects of a medical unit on space aircraft]. 20082292877
early response with clomipramine in obsessive compulsive disorder--a placebo controlled study.1. clomipramine has been found to be effective in the treatment of obsessive compulsive disorder (ocd) in nine placebo controlled studies whereas other conventional antidepressants lacking 5-ht reuptake inhibiting properties do not appear to be effective. 2. the placebo response rate in ocd is very low as is seen in the placebo controlled study of the efficacy of clomipramine 75mg in 14 patients suffering from ocd reported here. 3. response appears early in treatment when compared with response ...20082293252
vibrio vulnificus wound infection treated successfully with oral ciprofloxacin. 19902299188
osteomyelitis caused by vibrio vulnificus. 19902299219
polyvibrio infections: vibrio vulnificus and vibrio parahaemolyticus dual wound and multiple site infections. 19902299220
vibrio vulnificus infections in the hand. report of three patients. 19902303515
digestibility of cotton plant by-product diets for sheep at two levels of intake.crossbred wethers (n = 48) were assigned randomly to 1 of 12 experimental diets, arranged in a 3 x 2 x 2 split plot to evaluate three levels of cotton plant by-product (25, 50 and 75% cpb), two levels of naoh treatment of cpb (0 and 4%) and two levels of monensin supplementation (0 and 30 ppm, dm basis) at two intake levels (70 and 90% of ad libitum). intake was a within-lamb variable. ad libitum intake was established over an initial 17-d adjustment period. feed intake and fecal output were rec ...19902312420
primary vibrio vulnificus sepsis in kentucky.vibrio vulnificus is associated with infection acquired during contact with sea water or with seafood, and is seldom suspected by physicians in noncoastal states. the ease of transportation of fresh raw seafood has facilitated this organism's capacity to produce disease in geographic areas in which it was previously unseen. we have reported a case of fatal vibrio vulnificus sepsis acquired from ingestion of fresh oysters in the inland united states.19902315791
long-term clearance of inhaled uo2 particles from the pulmonary region of the rat.this paper reports on an enriched uranium dioxide (uo2) mass clearance study undertaken with fischer-344 rats. the uo2 had a uranium (u) isotopic composition of 0.79% 234u, 92.8% 235u, 0.34% 236u and 6.06% 238u, by mass, with an alpha-particle activity of 1.91 bq micrograms-1. forty-six rats were exposed to an enriched uo2 aerosol that had an activity median particle aerodynamic diameter ranging from 2.7 to 3.2 microns. the rats were killed from 1 to 720 d post-inhalation (pi). the mass of enric ...19902323929
phytochrome from the green alga mesotaenium caldariorum. purification and preliminary characterization.a method to purify the phytochrome photoreceptor from the unicellular green alga mesotaenium caldariorum is presented. preparative scale formation of algal protoplasts and controlled osmotic cell lysis have permitted separation of intact organelles from the phytochrome-enriched soluble protein fraction. we have utilized the observation that red light-absorbing (pr) and far-red light-absorbing (pfr) forms of phytochrome are differentially retained on an anion exchange matrix to purify m. caldario ...20082324111
contempo '90. 20082329645
[neoplasms of the meckel diverticulum. apropos of 2 new cases].we present two new cases of cancer in a meckel's diverticulum, representing 3.3% of the complicated meckel's diverticula encountered in our department. the first case was a carcinoid tumor encountered in a pathology study of an inflamed meckel's diverticulum, and the second case was a leiomyosarcoma on a meckel's diverticulum that presented as diverticular perforation. we emphasize the advanced age of the two patients and review the cases reported in spain and in the western literature.20082346684
casein and casein subunits in preterm milk, colostrum, and mature human milk.human milk proteins have both nutritional and physiological roles for the breast-fed infant. while the biochemistry and developmental patterns for many whey proteins are well known, our knowledge of human casein and its subunits is still limited. we have recently developed a method to isolate casein from whey proteins in human milk and to separate the casein subunits by fast protein liquid chromatography. in this study we have applied this methodology to study the casein subunit pattern in prete ...19902358977
pathogenesis of minimal change nephropathy. 20082362129
blockade of inhibition in a pathway with dual excitatory and inhibitory action unmasks a capability for ltp that is otherwise not expressed.long-term potentiation (ltp) can be readily elicited in a number of hippocampal pathways, but has not been seen in the dentate commissural pathway. the dentate commissural pathway is similar to the commissural/schaffer collateral projection to ca1 except that it produces powerful inhibition that occurs nearly concurrently with the excitation. the present study evaluates whether this inhibition prevents the pathway from expressing ltp. acute neurophysiological experiments were carried out in uret ...19902364294
the cytolysin gene of vibrio vulnificus: sequence and relationship to the vibrio cholerae e1 tor hemolysin gene.a cytolysin of ca. 56 kilodaltons has been suggested as a possible virulence factor in vibrio vulnificus infections. we sequenced the dna encoding cytolytic activity and found that the sequence contained two open reading frames, vvha and vvhb. vvha encoded the structural gene for the cytolysin and contained the n-terminal amino acid sequence previously reported for the protein. regions of the vvha gene showed homology to the structural gene for the vibrio cholerae e1 tor hemolysin.19902370116
contingent negative variation and reaction time of physically-trained subjects in simple and discriminative tasks.contingent negative variations (cnv) were recorded during the s1-s2 interval of two simple and one discriminative task at fz, cz and pz of 12 physically-trained college athletes and 12 non-trained students. the reaction time to s2 was also measured. the whole mean cnv amplitude average over the 2 sec s1-s2 interval and the segmented cnv amplitudes of the 250 msec epochs were submitted to 4-way anova (physical training x task x electrode position x gender), while the mean reaction time was analyz ...19952376531
Displaying items 701 - 800 of 3837