Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| thyroid-stimulating hormone and cyclic adenosine 3',5'-monophosphate in the regulation of thyroid gland function. | the initial step in tsh action reflects binding of the hormone to specific receptor sites on the plasma membrane. such binding has been studied using plasma membranes, homogenates, isolated thyroid cells grown in culture, and thyroid slices. 3-h- and iodinated tsh preparations have been used; the latter have been prepared using both chloramine-t and lactoperoxidase. some of the discrepancies reported in the literature might reflect the different thyroid and hormone preparations and the variable ... | 1975 | 165359 |
| cyclic amp and cyclic gmp: studies utilizing immunohistochemical techniques for the localization of the nucleotides in tissue. | antibodies to the cyclic nucleotides initially were utilized in radioimmunoassays for cyclic amp and cyclic gmp which might be present in mammalian tissues. allowed measurement of the nucleotides on small amounts of tissue in physiologic studies. to gain further insight into the relative roles of cyclic amp and cyclic gmp in cell function, these antibodies have been applied to immunohistochemical studies for the localization of the cyclic nucleotides in tissues and cells. this methodology is use ... | 1975 | 165362 |
| letter: anergy in patients with syphilis. | 1975 | 165417 | |
| immunoreactive thyrotrophin releasing factor in gastropod circumoesophageal ganglia. | 2003 | 165422 | |
| a simple radioimmunoassay for 3',5', cyclic adenosine monophosphate. | 1975 | 165745 | |
| breakage of yeast: a method for processing multiple samples. | 1975 | 165747 | |
| separation of tetracyclines by high-speed liquid chromatography. | the separation of tetracycline and its four commoninpurities has been studied by high-speed liquid chromatography. a preliminary study of the effectiveness of ion-exchange, adsorption, liquid-liquid partition and reversed-phase ion-pair chromatography indicated that only the last method showed promise. by developing special hydrocarbon-bonded stationary phases a rapid and complete resolution of all five tetracyclines has been obtained within 10 min. plate heights using a derivatised 18-mum parti ... | 2003 | 166085 |
| assignment of the configuration of the steroid spin label, 3-doxyl-5alpha-cholestane. | 2003 | 166109 | |
| chemotherapeutic nitroheterocycles. 18. 2-(5-nitro-2-imidazolylmethylene)-1-indanones, -1-tetralones, and -acetophenones substituted by aminoalkoxy groups. | 2-(5-nitro-2-imidazolylmethylene)-1-indanones, -1-tetralones, and -acetophenones substituted by aminoalkoxy groups and related compounds (41-69, table ii) were synthesized and their antimicrobial activities were evaluated (table iii). some of these compounds (e.g. 47, 52, and 59) suprisingly exhibited a broad antibacterial spectrum including proteus species and pseudomonas aeruginosa. extraordinary antitrichomonal activities could also be observed in vitro (mic of compound 59, 0.0004 pg/ml) and ... | 1975 | 166185 |
| [experimental investigations concerning spectrum, serum concentration, and excretion of spectacillin (author's transl)]. | by means of the diffusion test, the range of action of the ampicillin successive preparation spectacillin was determined using 12 000 pathological germs freshly isolated from in-patients. the result was a range of action similar to that of ampicillin. a comparison, however, is only possible in case the test platelets (without over-dosage) are each charged with exactly, e.g., 25 gamma. the analyses of serum concentrations have shown that spectacillin is satisfactorily absorbed after oral as well ... | 1975 | 166292 |
| enhancement of adenovirus infection in wi-38 and agmk cells by pretreatment of cells with 5-iododeoxyuridine. | 1975 | 166491 | |
| the use of nuclear medicine in evaluating liver disease. | 1975 | 167451 | |
| interactions of heteroaromatic compounds with nucleic acids. 2. influence of substituents on the base and sequence specificity of intercalating ligands. | this paper presents the results of a systematic study on the effects of substituents on the base and sequence specificity of tricyclic heteroaromatic compounds interacting with dna by intercalation. all the compounds tested are derived from proflavine and acridine orange analogs with different heteroatoms in the middle ring. their base and sequence specificities were determined by differential dialysis of the ligand against dna samples of differing g-c content. the main results indicate that (a) ... | 1975 | 168079 |
| evaluation of different antibiotic actions combined with rifampicin. in vitro synergism against pseudomonas and proteus. | associations of penicillin, streptomycin, tetracycline and polymyxin b with rifampicin were tested for synergism against pseudomonas and proteus pathological strains. the combination of rifampicin and polymyxin b was clearly synergistic for all strains as it was evaluated by isobolograms and killing curvesmthe bactericidal action of this association, without any cross-resistance between its components, may eradicate gram-negative bacteria infections with marked polyvalent drug resistances. | 1975 | 169107 |
| detection of agents that alter the bacterial cell surface. | proteus mirabilis is not killed by polymyxin b, normal serum, or sodium deoxycholate. exposure to polymyxin b renders the cells susceptible to killing by the latter two agents. the data suggest that this synergism is due to polymyxin b-induced surface changes. the results point out an inadequacy of existing methods of screening for antibiotics; they fail to detect agents which, while showing no in vitro effect on growth, may alter a resistant organism so that it becomes more susceptible to other ... | 1975 | 169728 |
| sequence of the cysteine peptide from the copper-subunit of bovine cardiac cytochrome oxidase. | 1975 | 169852 | |
| pancreatic cholera (w.d.h.a. syndrome). histochemical and ultrastructural studies. | results of light and electron-microscopic studies of primary pancreatic tumor and of metastasis in a new case of pancreatic cholera (p.c.) are reported. the primary tumor but not the metastases, contained unusual, large cystic glandular formations, lined both by pancreatic-duct- and small-intestine-like epithelia and closely connected with the endocrine proliferation. a part from a few d-cells, the endocrine tumoral cells could not be identified by histochemical stainings. their ultrastructural ... | 1977 | 170729 |
| [some epidemiological indicators in bronchopulmonary cancer in sector 5 of bucharest (study of 525 cases)]. | the incidence was studied of broncho-pulmonary carcinoma, as well as of other epidemiological indicators in the 5th district of bucharest over a period of 14 years (1960-1973) during which a total of 525 cases have occured. the incidence in this territory tends to become real from 1967 when the curve overtook the death-rate in the country. following a continuous increase the number of cases reached 29 0/0000 in 1973 and it is presumed that it will attain 40 0/0000 in 1980. the increase in the mo ... | 1990 | 171736 |
| the inactivation of bacteriophage r17 by ethylating agents: the lethal lesions. | the biological inactivation of bacteriophage r17 by ethyl methanesulphonate (ems) and n-ethyl-n-nitrosourea (enua) has been studied. at the mean lethal dose for the first compound 8 moles ethyl are bound/mole rna and with the nitroso compound 3.5 moles ethyl are bound. analysis of the amounts of the different ethylated derivatives formed shows that the toxicity of the sulphonate can be accounted for by the formation of 3-ethylcytosine, o6-ethylguanine, 1-ethyladenine and chain breaks produced on ... | 1988 | 172244 |
| [identification of camp dependant protein kinases in human lymphocytes]. | chromatographic purification by "deae" cellulose resolves the camp binding proteins in human lymphocytes into three parts. in presence of mg++ each one possesses camp dependent protein-kinase activity, one of them showing allosteric characteristics. | 1975 | 172248 |
| [resistance to association of antibiotics (polymyxin and penicillin) in relation to cell concentration of two bacterial species in the same inoculum. complementary inoculum effect]. | dense suspensions of sa. typhi (polys penr) and of st. aureus (polyr pens) proliferate on gelose medium added with the two antibiotics only if the inoculum is mixed. the growth is probably due to the partial neutralization of the antibiotics following the formation of complexes between these antibiotics and some constituents of the two strains. | 1975 | 172250 |
| assignment of the gene for human uridine monophosphate kinase to chromosome 1 using somatic cell hybrid clone panels. | evidence from mouse-human somatic cell hybrids is presented for the assignment of the gene for uridine monophosphate kinase (atp: nucleoside monophosphate phosphotransferase, e.c. 2.7.4.4) to human chromosome 1. the use of the "clone panel" in this determination and its value as a systematic method for gene mapping is discussed. | 1975 | 172293 |
| reversible inhibition of camp-induced axon formation in neuroblastoma cells by concanavalin a and vinblastine. relationship to microtubules and cytotoxicity. | 1988 | 172349 | |
| synthesis and evaluation of (des-asp1)angiotensin i as a precursor for (des-asp1)angiotensin ii ("angiotensin iii"). | the nonapeptide [des-asp1]angiotensin i (iv), synthesized by merrifield's solid-phase procedure, was tested as a possible substrate for the converting enzymes from porcine lung and plasma. iv, [des-asp1]angiotensin ii (iii), [des-(asp1,arg2)]angiotensin ii (v), [des-(asp1,arg2,val3)]angiotensin ii (vi), [sar1,ile8]angiotensin ii (vii), and [des-asp1,ile8]angiotensin ii (viii) possessed 0.5, 20, 2, 0 less than 0.1, and less than 0.01% of the inotropic activity (rabbit atria), 1, 15, 5, 0, 3, and ... | 1975 | 172631 |
| inhibition of hepatic lipogenesis by adenine nucleotides. | incubation of liver slices and isolated liver cells with adenosine cyclic-3',5'-monophosphate at concentrations which inhibit lipogenesis was found to expand the pool size of the noncyclic adenine nucleotides in the intact cells of the preparations. this observation led to studies which demonstrated that adenosine and adenosine-5'-monophosphate also inhibited lipogenesis and expanded the adenine nucleotide pool size. it is proposed but not proven that the increase in intracellular nucleotides pr ... | 1975 | 172757 |
| persistence of cmv genome in lymphoid cells after congenital infection. | 1975 | 172796 | |
| [effect of a chronic iodine deficit in the ration on the development of the infectious process]. | it was revealed that the infectious process in albino rats kept for 4-5 months on an iodine-deficiency diet was characterised by a tendency to dissemination. the seeding efficiency from the parenchymatous organs increased in such animals significantly, whereas the bactericidal properties of the plasma and the phagocytic activity of blood neutrophils decreased; this was apparently associated with depression of the intracellular metabolism reflected in reduction of the cytochromoxidase and peroxid ... | 1975 | 173121 |
| ascorbic acid and collagen synthesis in cultured fibroblasts. | 1995 | 173226 | |
| myasthenic syndrome studied with single fiber electromyography. | a patient with the myasthenic syndrome was investigated with single fiber electromyography (sfemg). it was found that 35 of 36 potential pairs had increased "jitter" and that 29 of these demonstrated impulse blockings. there was improvement in neuromuscular transmission with higher rates of innervation. transmission worsened following rest. the sfemg findings at the motor end-plate level correlate well with the results of repetitive stimulation and in vitro studies. | 1995 | 173269 |
| proceedings: a simple test for patency of portacaval shunts. | 1995 | 173627 | |
| selective deficit in feeding behavior following the antero-medial amygdaloid lesions in cats. | 1975 | 174387 | |
| catecholamine secretion by isolated adrenal cells. | isolated adrenal cells were prepared by collagenase digestion of guinea pig adrenal glands. acetylcholine stimulates the secretion of catecholamines by these isolated adrenal cells. acetylcholine-stimulated catecholamine secretion is inhibited by cholinergic blocking agents (atropine and hexamethonium) and by local anaesthetics (tetracaine), and is dependent upon the concentration of ca2+ in the incubation medium. in the presence of ca2+, catecholamine secretion is also stimulated by two divalen ... | 1976 | 174736 |
| [immunologic results obtained with an experimental system oftransplantable colonic tumors. possible applications of these results to human intestinal tumors]. | intestinal cancers, morphologically very close to human colo-rectal adeno-carcinoma, have been induced by dimethylhydrazine in inbred rats. graftable lines have been obtained from 5 primary intestinal tumors, and 3 cell lines have been cultivated from the grafts. this model was used to demonstrate carcinofetal antigen(s) on the surface of the intestinal cancer cells. circulating antibodies against tumor-associated antigen(s) have been found in tumor-bearing rats. cancer enhancement was regularly ... | 1975 | 174767 |
| letter: liver tumours and the pill. | 1987 | 174777 | |
| [diagnostic errors and their reasons in tumors and preblastomatoses of the skin. results of a statistical evaluation]. | clinical and histological findings and other available data of 6 521 skin excisates were compared with regard to differential diagnosis. it appears from our findings, that "naive" experience must be replaced by secured knowledge concerning frequencies of wrong diagnoses in definite situations, possible causes of errors, age-, sex-, and local distribution of different skin tumours. this knowledge may be a contribution to the improvement of clinical diagnoses. | 1987 | 175036 |
| the effects of dbcamp on adreanl chromaffin cells in organotypic culture. | chromaffin cells in organotypic cultures of adrenal glands from 19 day rat embryos developed a marked increase in the volume of their rough endoplasmic reticulum (rer) and enlargement of nucleoli in response to 1 mm dibutyryl cyclic amp (dbcamp) treatment for 17 days in vitro. 0.1 mm dbcamp had a similar but less dramatic effect. when dbcamp was removed from the medium after 11 days in vitro, cells became more like control explants treated with no additives, suggesting the effects of dbcamp were ... | 1976 | 175136 |
| [pathogenic and therapeutic concepts in viral hepatitis]. | 1976 | 175890 | |
| apoproteins of the lipoproteins in a nonrecirculating perfusate of rat liver. | the apoproteins of serum lipoproteins and of lipoproteins present in a nonrecirculating perfusate of rat liver were compared by immunochemical, gel electrophoretic, and solubility techniques. serum and perfusate very low density lipoprotein apoprotein composition were not different. no evidence for the presence of a lipoprotein resembling serum low density lipoprotein was obtained. however, the apoprotein composition of circulatory high density lipoprotein was quantitatively different from the s ... | 1976 | 176290 |
| growth in semisolid agar medium of human cord leukocytes freshly transformed by epstein-barr virus. | the semisolid agar method for the selective growth of transformed cells was applied to investigations of epstein-barr virus (ebv) transformation. when 1 x 10(5) human umbilical-cord blood leukocytes were seeded in agar medium immediately after ebv exposure, about 100 colonies developed in each dish. the occurrence of colonies correlated well with dilutions of ebv inoculum. these colonies were composed of lymphoblasts, were positive for ebv-determined nuclear antigen immunofluorescence, and cons ... | 1976 | 176377 |
| defects in granulocyte function in various chromosome abnormalities (down's-, edwards'-, cri-du-chat syndrome). | in five infants with autosomal aberrations and diminished resistance to infection (in spite of intact humoral and cellular immune mechanisms) several granulocyte functions (chemotaxis, phagocytosis, intracellular killing and metabolism of killing) were measured. a serum-dependent or a cell-dependent disturbance of phagocytosis of candida albicans was found in two infants with cat-cry syndrome and one with trisomy 18. in one of these children there was an additional serum dependent defect of the ... | 1976 | 176505 |
| superinfection epithelial nasopharyngeal carcinoma cells with epstein-barr virus. | attempts were made to superinfect epithelial explant cell cultures prepared from nasopharyngeal carcinomas with epstein-barr virus. virus-specific markers were observed in such cultures 3 days after superinfection. in addition, expression of epstein-barr virus early antigens was observed in epithelial cell explant cultures treated with iododeoxyuridine. the results suggest that epithelial cells of at least certain nasopharyngeal carcinomas possess the receptor for the epstein-barr virus and that ... | 1976 | 176664 |
| antibacterial activity of oxidized regenerated cellulose. | it has been demonstrated that oxidized regenerated cellulose promptly and markedly reduces the bacterial census of ten different strains of common pathogens when exposed to them in vitro. this was not true of two other hemostatic agents tested, namely, absorbable gelatin sponge and topical thrombin. wounds in guinea pigs in which oxidized regenerated cellulose was placed and infected with one of three pathogens had healing per primum in 39 of 40 instances. in similar control wounds and incisions ... | 1976 | 176740 |
| [the effect of standardised sodium hypochlorite solution on bacteria pathogenic for the urinary tract (author's transl)]. | stable sodium hypochlorite solution shows excellent disinfectant properties, even in higher dilution. parallel to clinical tests in vitro experiments were made to show the changes of morphology of bacteria pathogenic for the urinary tract by scanning microscope. two hours after incubation of the bacteria with sodium hypochlorite solution containing 40 mg available chlorine/1 severe damages of the bacterial morphology up to complete destruction were evident in all cases. gram-negative rod-shaped ... | 1976 | 176759 |
| enzymic degradation of collagen. | 1995 | 177377 | |
| formation in the dark, of virus-induced deoxyribonuclease activity in anacystis nidulans, an obligate photoautotroph. | in anacystis nidulans, upon infection with cyanophage as-1, after a lag period of 1 h the level of deoxyribonuclease (dnase) activity increaded rapidly up to 15- to 20-fold in 4 to 5 h in the light. in contrast, the ribonuclease and phosphomonoesterase activities increased significantly only 4 to 5 h after infection, i.e. as late as 1 h prior to lysis. in complete darkness, the nuclease levels remained unaltered. however, when the infected cells were exposed to light for 1 or 2 h after infection ... | 1976 | 177400 |
| interaction of swine lipoproteins with the low density lipoprotein receptor in human fibroblasts. | hdlc, a cholesterol-rich lipoprotein that accumulates in the plasma of cholesterol-fed swine, was shown to resemble functionally human and swine low density lipoprotein in its ability to bind to the low density lipoprotein receptor in monolayers of cultured human fibroblasts. this binding occurred even though hdlc lacked detectable apoprotein b, which is the major protein of low density lipoprotein. after it was bound to the low density lipoprotein receptor, hdlc, like human and swine low densit ... | 1976 | 177413 |
| the therapeutic community and the nurse: a blurring of traditional roles. | 1996 | 177765 | |
| pituitary cyclic amp production and mechanism of luteinizing hormone release. | 1975 | 178535 | |
| the enzymatic reduction of k-vitamins incorporated in the membrane of liposomes. | 1975 | 178539 | |
| selection of cell culture systems for virus isolation. | a survey of cell culture systems for virus isolation is presented. because there is not single cell culture system which will support the many viruses that may be encountered in clinical specimens, the characteristics and susceptibility of primary, diploid, and continuous cell cultures are reviewed. the primary cell culture system should be susceptible to infection with myxoviruses, paramyxoviruses, adenoviruses, and coxsackie b viruses, since these are not consistently recognized in diploid cel ... | 1976 | 179319 |
| paul a. bishop memorial. | 1997 | 179433 | |
| steroid production by quartered and capsular rat adrenal gland in response to haemorrhage. | 60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ... | 1975 | 179800 |
| cytokinin ocntents and camp metabolism during growth of escherchia coli. | during escherichia coli growth, we found an inverse correlation between free cytokinin content and camp level. the rates of synthesis of adenylate-cyclase and camp-phosphodiesterase were practically constant. | 1976 | 179840 |
| [changes in the functional state and structure of the adrenals in cc14 poisoning]. | introduction of cci4 in doses of 0.1 and 0.2 ml/100 g to albino rats reduced the steroid production generated by adrenal sections. in 24 and 48 hours after poisoning with a small dose of cci4 (0.1 ml/100 g) there could be seen an increased concentration of 11-oxycorticosteroids in the plasma. morphological signs of a damage suffered by the gland were observed only in poisoning with a large dose of cci4 (0.2 ml/100 g). | 1975 | 179852 |
| enzyme-inducing agents and their effect on vitamin d metabolism. | 1984 | 179922 | |
| experimental encephalitis caused by herpes simplex virus: comparison of treatment with tilorone hydrochloride and phosphonoacetic acid. | a mouse model of encephalitis caused by herpes simplex virus was used to compare the antiviral activity of tilorone hydrochloride with that of phosphonoacetic acid. these compounds were also administered simultaneously to determine whether the combination had a synergistic effect. rates of survival and concentrations of virus in brain were used as criteria for judging the effectiveness of treatment. the fatal course of encephalitis was not altered by any treatment protocols in which tilorone hyd ... | 1976 | 180204 |
| uptake of circulating iron by the duodenum of normal mice and mice with altered iron stores, including sex-linked anemia: high resolution radioautographic study. | using electron microscopy radioautography, the deposition of intravenously administered iron in the duodenal epithelium was studied in normal mice, iron-overloaded and iron-deficient mice, and in mice with x-linked anemia (gene symbol sla) 4 and 24 hours after injection of 59fe. the resolution of radioautography with 59fe was determined with a line source and the distance from the hot line within which half of the grains fell (hd value) was 1650 a. in normal, iron-overloaded, and sla mice, radio ... | 1985 | 180329 |
| genetics of resistance of fowl to infection by rna tumour viruses. | 1976 | 180540 | |
| [epidemiological aspects of cytomegalovirus infections]. | 1975 | 180573 | |
| combinations of antimicrobial agents: ii. the in vitro sensitivity of 52 strains of proteus species to sulphafurazole, polymyxins and combinations of sulphafurazole and polymyxins. | the sensitivity of 52 strains of proteus species to sulphafurazole, polymyxins and the combinations of sulphafurazole and polymyxins was determined by means of discs and trays. it was found that 2 and 6 strains, respectively, were sensitive to discs containing 100 mug sulphafurazole and 300 mug polymyxin b, respectively, 41 strains were sensitive to the combination of discs containing 100 mug sulphafurazole and 50 mug colistin, respectively, and 38 strains were sensitive to the combination of di ... | 1976 | 180905 |
| aryl hydrocarbon hydroxylase induction in mammalian liver-derived cell cultures. effects of various metabolic inhibitors on the enzyme activity in hepatoma cells. | 1976 | 181006 | |
| in vivo activation by polymyxin b of phospholipase from pseudomonas aeruginosa and escherichia coli. | 1976 | 181357 | |
| thyroid peroxidase, thyroglobulin, camp and dna in human thyroid. | tissues from normal thyroid, euthyroid multinodular goiter, toxic goiter, hashimoto's thyroiditis, thyroid adenoma, and carcinoma were examined for their content of deoxyribonucleic acid (dna), thyroid peroxidase activity (tpa), thyroglobulin (tg), and adenosine 3',5'-cyclic monophosphate (camp). compared with normal thyroids dna was increased in the neoplastic tissues and decreased in euthyroid multinodular goiter. quantitative changes of thyroglobulin were observed, especially in the thyroid t ... | 1976 | 181398 |
| inhibition by rheumatoid factor, anti-fc, and staphylococcal protein a of antibody-dependent cell-mediated cytolysis against herpes simplex virus-infected cells. | incubation of herpes simplex virus-infected human fibroblasts with the serum from a patient with herpes labialis rendered the cells susceptible to immune lysis by human mononuclear leukocytes (mnl) as well as complement. if, before the addition of mnl, the antibody-treated, infected monolayers were incubated with either igm rheumatoid factor (rf), staphylococcal protein a (spa), or anti-fc gamma serum, antibody-dependent cell-mediated cytolysis (adcc) was markedly depressed. spa and anti-fc caus ... | 1976 | 181492 |
| neoplasia at the site of ureterosigmoidostomy. | an increased incidence of neoplasia at the site of ureterosigmoidostomy must be considered in patients being evaluated for or who have undergone this procedure. a case of mucinous adenocarcinoma 24 years following bilateral ureterosigmoidostomy is reported. this patient had bilateral hydroureteronephrosis, which led to left nephroureterectomy and right cutaneous ureterostomy. mucinous adenocarcinoma was diagnosed only after the edematous, protruding and inflamed cutaneous ureterostomy stoma was ... | 1981 | 181600 |
| [radioimmunological determination of plasma acth and beta-msh in congenital adrenal gland hyperplasia]. | 1981 | 181667 | |
| experimental myasthenia due to alpha-bungarotoxin. | neuromuscular transmission was studied electrophysiologically in rabbits intoxicated by alpha-bungarotoxin, a specific inhibitor of acetylcholine receptor. the findings consisted of a slight reduction in amplitude of single evoked muscle action potentials, a decrement in amplitude of successive evoked muscle action potentials post-tetanic potentiation and exhaustion, edrophonium reversal, and no change of muscle action potentials evoked by direct stimulation of the muscle. these were similar to ... | 1976 | 181695 |
| [immunogenetics of polyautoagression. reference to chronic obstructive bronchopneumopathy]. | 1982 | 181821 | |
| enzootic with ectromelia symptomatology in sprague-dowley rats. | 1976 | 181904 | |
| chemotherapy of virus diseases. | 1982 | 182044 | |
| effectiveness of orally administered bordetella pertussis vaccine in mice. | oral administration of killed bordetella pertussis organisms to mice results in increased resistance to an intracerebral infection with virulent b. pertussis cells. the rate of survival is dependent on the dose of antigen. but besides specific systemic immunity, which is persistent over a long period, also transient non-specific resistance is increased. these effects are evidently induced without penetration of bacterial substances into the circulation. | 1976 | 182602 |
| [melanotic progonoma. report of two cases (author's transl)]. | 2003 | 182628 | |
| the biochemistry of sugars. | in animal cells the utilization of sugars involves one or more of the three major pathways known to occur in these cells. the glycolytic (embden-meyerhof) pathway is quantitatively the most important, and this pathway, coupled to the citric acid cycle, serves as a major source of energy. glycolysis and the citric acid cycle also provide most of the precursors for the synthesis of proteins, nucleic acids and lipids. the pentose phosphate, or hexose monophosphate oxidation, pathway is a major sour ... | 2003 | 182650 |
| growth inhibition of proteus mirabilis by cyclic adenosine 3'-5'-monophosphate. | growth of proteus mirabilis on a synthetic agar medium containing either glycerol, galactose, or trehalose as the sole source is inhibited by 5 mm cyclic adenosine 3',5'-monophosphate (camp). inhibition on an agar medium is evident as loss of viability, but in broth camp only slightly inhibits growth rate. inhibition is associated with the accumulation of methylglyoxal in the medium. a nonswarming mutant of p. mirabilis is not inhibited by camp on either of the three carbon sources, but it is se ... | 1976 | 182676 |
| biosynthetic direction substrate kinetics and product inhibition studies on the first enzyme of histidine biosynthesis, adenosine triphosphate phosphoribosyltransferase. | 1976 | 183121 | |
| oncornavirus-host interaction in gibbons. | 1982 | 183667 | |
| virus-induced murine leukemia involving two subpopulations of lymphocytes. | 1975 | 183714 | |
| cyclic nucleotides in transformation. | 1982 | 183732 | |
| phosphorylated sites of calf thymus h2b histone by adenosine 3':5'-monophosphate-dependent protein kinase from bovine cerebellum. | 1976 | 183776 | |
| [proceedings: sleep and psychotropic drugs: clinical aspects (author's transl)]. | 1982 | 183791 | |
| membranous nephropathy long-term follow-up and association with neoplasia. | a ten years follow-up has been made on 66 patients with membranous glomerulonephritis. eighty per cent of them showed nephrotic syndrome, one third elevated diastolic pressure and in 50% of the patients the gfr was reduced. histopathologic stating and evolution were made as described by ehrenreich histology with clinic and prognosis. seven of 76 cases (11%) showed association with neoplasia; different pathogenetic hypothesis could be risen by this observation. the five year survival was 84% and ... | 1982 | 183797 |
| annealing and hybridization properties of herpes simplex virus type 1 dna. | the hybridization properties of the herpes simplex virus type 1 (hsv) genome have been analysed. the dna has a kinetic complexity of 1 x 10(-8). e. cole rna polymerase was found to initiate synthesis at about 70 sites on the hsv dna. the in vitro rna product from this reaction was complementary to about 80% of the hsv genome. the rna-dna hybridization rate constant (kh) was determined using conditions of both rna excess and dna excess. using this rate constant one can analyse the content of hsv ... | 1976 | 184238 |
| characterization of a stable spheroplast type l-form of proteus mirabilis d 52 as cell envelope mutant. ii. electronmicroscopic investigations. | the ultrastructural analysis of a stable spheroplast type l-form of proteus mirabilis d 52 revealed characteristic alterations in the organization of the cell envelope including defective changes in the cell envelope structure as for instance the loss of a coherent murein layer, the loss of some components in the outer cell wall layer, the formation of small membraneous vesicles at the tips of loose extensions of the cell wall, a decrease in associations and bindings between wall and membrane, a ... | 1976 | 184605 |
| [neuroanatomic bases of lesions and healing prospects in peripheral nerves]. | 1983 | 184607 | |
| mapping viral integration sites in somatic cell hybrids. | 1983 | 185015 | |
| the role of cyclic adenosine monophosphate in the swarming phenomenon of proteus mirabilis. | the levels of cylic amp and adenyl cyclase in swarming and non-swarming cells of proteus mirabilis and the effect of glucose on swarming have been investigated. the results indicate the camp is required for swarming, but that the flagellar derepression characteristic of swarming does not result from increased camp levels. | 1976 | 185081 |
| normal rabbit alveolar macrophages. ii. their primary and secondary lysosomes as revealed by electron microscopy and cytochemistry. | in this investigation, vacuoles containing tubular myelin proved to be digestive compartments with cytochemical reactivity for acid phosphatase and arylsulfatase. these cytochemical markers identify the secondary lysosomes, known to contain enzymes capable of hydrolyzing phospholipids like surfactant. therefore, it appears that alveolar macrophages possess the enzymatic machinery for the degradation of the tubular myelin found in their digestive vacuoles. although it thus appears evident that al ... | 1976 | 185318 |
| enumeration of antigen reactive t cells against sheep erythrocytes by the virus plaque assay. | 1976 | 185443 | |
| biological values of the infant, juvenile, and adult agouti (dasyprocta sp) with emphasis on microbial flora. | normal values for intestinal flora were determined on four adult, two juvenile, and four infant agoutis (dasyprocta sp) maintained at our institution. serologic, hematologic, biochemical, and histologic observations were also made on these same agoutis, and serologic, microbiologic, and endoparasitic tests were made on serum and fecal samples from agoutis maintained at other institutions. streptococci, lactobacilli and nonenteropathogenic escherichia coli were isolated from cecal contents of all ... | 1976 | 185456 |
| hypertensive effect of 17alpha, 20alpha-dihydroxyprogesterone and 17alpha-hydroxyprogesterone in the sheep. | 1976 | 185522 | |
| [the role of arteriography in the diagnosis of abdominal tumours in children. part iv. hepatic tumours (author's transl)]. | 1984 | 185597 | |
| opiate receptor: autoradiographic localization in rat brain. | opiate receptor sites in rat brain can be labeled in vivo by [3h]diprenorphine, a potent opiate antagoinst. using techniques to minimize diffusion in fresh, frozen, unfixed brain, we have localized [3h]diprenorphine by autoradiography to visualize the distribution of opiate receptors. silver grains indicative of the binding of labeled [3h]diprenorphine are discretely localized in numerous areas of the brain with very high densities in the locus coeruleus, the substantia gelatinosa of the spinal ... | 1976 | 185626 |
| adenomatous polyps in the stomachs of hatchery-grown salmonids and other types of fishes. | 1982 | 185653 | |
| estimation of membrane surface potential and charge density from the phase equilibrium of a paramagnetic amphiphile. | the distribution of a paramagnetic amphiphile, n,n-dimethyl-n-nonyl-n-tempoylammonium ion, between the membranes of charged phospholipid vesicles and the surrounding aqueous medium was studied by electron paramagnetic resonance spectroscopy. by systematically varying the surface charge of the vesicles and the aqueous electrolyte concentration, the distribution was shown to indicate vesicle surface potential. at each fixed phospholipid composition, the surface potential exhibited a dependence on ... | 1994 | 186095 |
| [possible participation of cyclic amp in regulating acid hydrolase activity in muscle tissue in avitaminosis e and denervation]. | in the muscles of denervated and vitamin e-deficient rabbits the level of 3', 5'-cyclic amp proved to decrease with a simultaneous increase in the activity of camp phosphodiesterase. in vivo experiments showed that at the concentration of 10(-4) camp was capable of retarding the release of acid phosphatase from the lysosome-rich fraction obtained from the muscles of e-deficient rabbits. thus, in muscular dystrophy elevation of acid hydrolase activity in the skeletal muscle was due to leakage of ... | 1976 | 186139 |
| serologic comparison of hepatitis a antigen to echovirus 25 isolate cr69(076) recovered from a patient with viral hepatitis. | a serologic comparison was performed by immune electron microscopy between hepatitis a antigen (related to the ms-1 strain of hepatitis a virus) and a viral isolate, cr69(076), from the stool of a patient in costa rica with viral hepatitis. cr69(076) was not antigenically related to hepatitis a antigen but was related to echovirus 25. thus, it is unrelated to the ms-1 strain of hepatitis a virus. | 1975 | 186440 |
| biomaterials and collagen synthesis. | a highly reactive biomaterial (clay) and a relatively nonreactive substance (silicone) were implanted separately in primarily closed incisions on the backs of rats. collagen synthesis was determined in biopsies from each test site after 8 days. the biochemical measurements of collagen synthesis showed a significant correlation with the gross pathologic and histologic findings. | 1976 | 186458 |
| unconjugated dehydroepiandrosterone plasma levels in normal subjects from birth to adolescence in human: the use of a sensitive radioimmunoassay. | a specific and sensitive radioimmunoassay for measuring unconjugated plasma dehydroepiandrosterone (dha) has been developed and the results expressed in ng/100 ml. mean values +/-1 sd were in mixed cord blood 593.3 +/- 186.5 in 21 females and 712.7 +/- 190.9 in 18 males. during the first day of life the peripheral plasma concentration of dha was 917.6 +/- 317.8 in 22 female and 922.65 +/- 290 in 17 male neonates. during the first month of age, dha levels decreased significantly and then more pro ... | 1976 | 186482 |
| regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes. | circulating human lymphocytes freshly isolated from venous blood of 15 normal subjects exhibited a low capacity to bind, take up, and degrade 125i-labeled low density lipoprotein (ldl). however, when these cells were incubated for 72 h in the absence of lipoproteins, they gradually acquired in increased number of high affinity cell surface receptors for ldl. the increase in the number of ldl receptors was associated with a 16-fold increase in the rate at which the cells were able to take up and ... | 1976 | 186492 |
| a cell type in sponges involved in the metabolism of glycogen. the gray cells. | the gray cells of four orders of demosponges contain basophilic inclusions and glycogen. they are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema). they do not occur in larvae; but all the phases of their differentiation from the flagellar cells of the larva have been demonstrated. | 2003 | 187347 |