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hydranencephaly and maximal hydrocephalus: usefulness of electrophysiological studies for their differentiation.the eeg was evaluated in three cases of hydranencephaly and two cases of maximal hydrocephalus, and the visual evoked potential was studied in one case each of hydranencephaly and maximal hydrocephalus. the eeg tracing of hydranencephaly typically showed a flat pattern in most bipolar derivations because of the differential amplification of the same activity from remote generators. however, the eeg of maximal hydrocephalus did not demonstrate a flat pattern in bipolar as well as referential deri ...20092715606
congenital choroid plexus papilloma of the fourth ventricle.a newborn infant with marked hydrocephalus had a large papilloma of the choroid plexus originating in the fourth ventricle and infiltrating the brain stem. the computed tomographic (ct) scan appearance was distinctive, showing vascularity and marked enhancement with contrast medium. histological confirmation was made from several surgical sites. total removal of the tumor was not possible. review of congenital choroid plexus brain tumors reveals the location of this child's tumor in the fourth v ...20092715609
acute pseudobulbar palsy due to bilateral focal cortical damage: the opercular syndrome of foix-chavany-marie.two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. the seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. bilateral destructive lesions in the opercular regions evolved on computed tomographic scans. both children were treated with acyclovir relatively early in the illness, and cerebrospinal fluid and serum antibodies support the dia ...20092715610
epidemiology and control of melanoma in white populations and in japan.in white populations living at moderate or low latitudes, melanoma has become one of the most common tumors in young adults. epidemiologic studies show a complex association with sun exposure. risk is related positively to the levels of exposure typical of the place of residence, and also to personally controlled exposure, with the maximum risk being related to acute intermittent exposure. risk also varies with pigmentation, family history of melanoma, and the presence of benign and of dysplasti ...20092715653
comparison of acral nevomelanocytic proliferations in japanese and whites.the preponderance of malignant melanomas that occur in the japanese population affect the palmar and plantar areas, in contrast to those of whites, which occur predominantly on the head, neck, and trunk. furthermore, a precursor lesion, the dysplastic nevus, has been well defined in nonacral white skin but not in the japanese. in this paper, a similarity between benign and atypical acral nevomelanocytic proliferations in japanese and whites is described. however, it appears that in the japanese ...20092715654
sabbatical leave: an important mechanism for revitalizing faculty. 20092715679
heparin-associated thrombocytopenia and thrombosis. 20092715686
flexible oesophagogastroscopy in otolaryngology.we describe a technique of flexible endoscopy of the upper aerodigestive tract which provides excellent visualization for diagnostic and therapeutic purposes in ent practice. with the present day need to reduce costs it is helpful to reduce inpatient workload and perform procedures as day cases where appropriate. the previous criticisms of flexible oesophagoscopy by ent surgeons are unfounded and indeed there are situations where flexible endoscopy is superior to rigid examination. we would reco ...20092715694
right vocal cord paralysis after internal jugular vein cannulation.neurological complications are rare after central venous cannulation. we report a case of right vocal cord paralysis after internal jugular vein cannulation. the mechanism of neural injury is discussed.20092715702
beyond the learning mystique: an interactional perspective on learning disabilities. 20092715715
apolipoprotein b metabolism in homozygous familial hypercholesterolemia.this report describes the metabolism of apolipoprotein b-containing lipoproteins in seven familial hypercholesterolemic (fh) homozygotes and compares the results to the values obtained from five healthy control subjects. the concentration, composition, and metabolism of large, triglyceride-rich very low density lipoproteins (vldl1, sf 60-400) were the same in the control and fh groups, indicating that this component of the vldl delipidation cascade ws unaffected by the absence of receptors. in c ...20092715722
effects of inducers of differentiation on protein kinase c and cmp-n-acetylneuraminic acid:lactosylceramide sialyltransferase activities of hl-60 leukemia cells.exposure of hl-60 leukemia cells to either 12-o-tetradecanoylphorbol-13-acetate (tpa), dimethylsulfoxide (dmso), exogenous gangliosides gm3, gm1, or bovine brain ganglioside mixture (bbg) resulted in a marked inhibition of the growth of cells. the order of the inhibitory potency was tpa greater than gm3 greater than dmso greater than bbg greater than gm1. in contrast, sulfatides were without effect on cellular replication. treatment of hl-60 cells with tpa or gm3 induced differentiation along th ...19892715723
determination of stereo- and positional isomers of oxygenated triterpenoids by reversed phase high performance liquid chromatography.twenty four oxygenated triterpenoids, including eight pairs of stereoisomers and five pairs of positional isomers, could be separated by reversed phase hplc. the capacity factors obtained in methanol-water and acetonitrile-water solvent systems made it possible to correlate the molecular polarities due to the presence of multiple oxygenated functional groups in these compounds. it was found that the number and position of functional groups as well as the stereochemistry of these functional group ...20092715731
[fibrinogen, atherosclerosis, inflammation. satellite symposium. angio dyn 88. toulouse, 5 october 1988. proceedings]. 20092715733
blunt injury of the abdominal aorta. 20092716321
[the primary care physician and the problems of aid to patients with acquired immunodeficiency syndrome]. 20092716378
patterns of ribosomal rna evolution in salamanders.sequence comparisons are presented for four segments of the large subunit of ribosomal rna, including divergent domains d7a and d7b, portions of the large divergent domains d2, d3, and d8, and evolutionarily conservative sequences flanking divergent domains. these results resolve phylogenetic relationships among exemplars of seven families of salamanders and the three amphibian orders. phylogenetic analysis confirms the prediction that divergent domains feature the highest relative rates of base ...20092716516
epidermal growth factor receptor status and s-phase fractions in gastric carcinoma.the correlation with epidermal growth factor (egf) receptor expression and clinicopathologic findings were studied in 242 gastric carcinomas. they were stained for egf receptor by means of an immunohistochemical technique using a monoclonal antibody against the receptor. s-phase fractions were measured by in vivo bromodeoxyuridine (brdu) labeling and indirect immunohistochemical staining using anti-brdu monoclonal antibody. in normal gastric epithelium, egf receptor immunoreactivity could not be ...20092717125
wound hematoma: prophylaxis with topical thrombin.we studied 123 patients having elective exploratory laparotomy through a midline vertical incision for gynecologic disease; patients were randomized to receive wound irrigation with either saline or topical thrombin before closure of the incision. seven patients were not evaluable. no patient received low-dose heparin therapy perioperatively. no patient in either group had a clinically significant wound hematoma or disruption. minor wound hematomas were more common in the saline group, a finding ...20092717986
tumor necrosis factor enhances expression of tissue factor mrna in endothelial cells.we have examined the effect of recombinant tumor necrosis factor on the expression of tissue factor activity and tissue factor mrna levels in vascular endothelial cells. following exposure of human umbilical vein endothelial cells to this cytokine, the appearance of tissue factor procoagulant activity was detected following cell disruption, and was maximal at 6 hours. northern blot analysis of cytokine-treated cells demonstrated a similar increase in the synthesis of tissue factor mrna, followed ...19892718149
survival and weight increase in the fetal rat after selective hypophysectomy in utero.rat fetuses were subjected to selective hypophysectomy in utero on day 16, 17 or 18 of gestation and inspected on day 22 (the day before birth). the survival rate of fetuses operated on day 17 and 18 was about 20 and 50%, respectively. losses were mostly caused by the surgery preceding the removal of the pituitary, and no significant survival-promoting activity of the gland could be demonstrated. the surgical injuries, as such, also reduced the weight increase substantially. still, the loss of t ...19892718734
improved catheter introducer with recessed sheath. 20092718884
analysis of the quantitative relationship between anemia and chronic renal failure.the authors analyzed data from 106 adults with chronic renal failure [(crf), serum creatinine (scr) greater than 132.6 mumol/l (1.5 mg/dl)], to define the precision of, and effects of covariables on, the relationship between anemia and crf. we excluded dialyzed or patients who had received transplants and those with obvious potential nonrenal causes of anemia. hct was a linear function of bun and scr (r = -0.48, and r = -0.67, respectively), and a curvilinear function of creatinine clearance (r ...20092719057
[viral infection and obstructive cholangiography in children].in the last years it has been suggested that idiopathic obstructive cholangiopathy is a pathologic process with evolutive studies: extrahepatic biliary atresia and neonatal hepatitis. the possibility of a viral agent as the inciting factor has been investigated. this report shows four male and one female with confirmed idiopathic obstructive cholangiopathy with different clinical picture. there was evidence of cytomegalovirus infection in two patients, rubella infection in one patient, hepatitis ...19892719422
genetic and environmental contributions to the covariance between occupational status, educational attainment, and iq: a study of twins.scores of occupational status, educational attainment, and iq were obtained for 507 monozygotic and 575 dizygotic male twin pairs born 1931-1935 and 1944-1960. a multivariate genetic analysis with statistics from different cohorts showed heterogeneity between cohorts, and analyses were performed in four separate cohorts. the only set of results which departed clearly from the rest was found for the group born 1931-1935, where the ratio of environmental to genetic effects exceeded those of the ot ...20092719624
preventing infant mortality. 20092719787
on the kinetic depth effect.the problem of the kinetic depth effect is revisited. we study how many points in how many views are necessary and sufficient to recover structure. the constraints in the cases where the velocities of the image points are known, and the positions of the image points are known with the correspondence between them established, are different and they have to be studied separately. in the case of two projections of any number of points there are infinitely many solutions, but if we regularize the pr ...20082719982
genetic susceptibility to environmental mutagens and carcinogens. 20082720142
non-oi vibrio cholerae septicemia associated with a motor vehicle accident. 19892720517
complications of cardiac catheterization and angiography in patients with valvular heart disease. va cooperative study on valvular heart disease.complications were surveyed prospectively in 2,029 catheterizations performed on 1,483 patients from the 13 centers participating in the va cooperative study on valvular heart disease. complications were reported in 6.9% of 1,559 preoperative procedures of which 2.6% were major and 0.2% fatal. clinical predictors of complications were hypertension and the precatheterization diagnosis of aortic stenosis. nevertheless, patients with aortic stenosis successfully tolerated left ventriculography, whi ...20092720763
composition of very-low-density lipoproteins in non-insulin-dependent diabetes mellitus.we studied the characteristics of very-low-density lipoproteins (vldls) composition in patients with non-insulin-dependent diabetes mellitus. vldls were isolated from 28 diabetics and 33 nondiabetics with a wide range of plasma lipid concentrations, so we could compare vldl composition between the two groups at similar lipid concentrations. the mean cholesterol and triglyceride concentrations in plasma of diabetic subjects were 2170 (sd 570) and 2510 (sd 2230) mg/l, respectively, and 2230 (sd 56 ...20092720974
a light microscopic and autoradiographic study of non-irradiated and irradiated ocular wounds.focal gamma irradiation was used to limit the intraocular extension of scar tissue which typically occurs after posterior perforating injury to the eye. standard posterior perforating injuries were created in the right eye of forty-eight rabbits, half of which had the site of perforation focally irradiated using a cobalt 60 ophthalmic plaque. non-irradiated wounds healed with profuse formation of highly cellular and vascularised granulation tissue which invaded the vitreous to form contractile v ...19892721224
a light microscopic and autoradiographic study of non-irradiated and irradiated ocular wounds.focal gamma irradiation was used to limit the intraocular extension of scar tissue which typically occurs after posterior perforating injury to the eye. standard posterior perforating injuries were created in the right eye of forty-eight rabbits, half of which had the site of perforation focally irradiated using a cobalt 60 ophthalmic plaque. non-irradiated wounds healed with profuse formation of highly cellular and vascularised granulation tissue which invaded the vitreous to form contractile v ...19892721224
[the classification of industrial chemical allergens].the classification of industrial chemical allergenic compounds has been developed. the criterion of noxious effect of allergenic chemicals is described not only by experimentally valid allergenic signs of the compound but also by clinical manifestations of allergosis in workers and sanitary diagnostic reliability of occupational allergic diseases. numerous allergens are classified according to the chemical systematization of compounds. the classification contains 2 classes: the 1st class involve ...20062722011
protection by desferrioxamine against histopathological changes of the liver in the post-oligaemic phase of clinical haemorrhagic shock in dogs: correlation with improved survival rate and recovery.haemorrhagic shock was produced in anaesthetized dogs, by rapid arterial bleeding to mean arterial blood pressure 35 mmhg, and maintained oligaemic for 4 h followed by return of withdrawn blood(rowb). dogs were observed for 72 h after rowb for survival and recovery, and, for histopathological (hp) studies on liver, dogs were sacrificed 2 h after rowb in non-survival experiments. desferrioxamine mesylate (25 mg/kg) was administered intra-muscularly at 2,3 and 4 h after blood loss in survival expe ...19892722020
vibrio cholerae expresses cell surface antigens during intestinal infection which are not expressed during in vitro culture.vibrio cholerae o1 bacteria harvested directly from ligated or nonligated intestines of rabbits with experimental cholera expressed at least 7 to 8 novel, in vivo-specific cell envelope (env) proteins that were not found on vibrios after in vitro culture in various ordinary liquid media. at the same time, several of the env proteins ordinarily expressed in vitro had disappeared or become much reduced. the infection-induced novel env protein were immunogenic. in immunoblot analyses, antisera rais ...19892722240
bilateral chorioretinitis, centripetal optic neuritis, and encephalitis in a llama.blindness characterized by dilated, unresponsive pupils and ophthalmoscopic evidence of optic nerve atrophy and retinal degeneration developed in a 5-year-old llama. lesions were not progressive during 2 months of observation. the llama was euthanatized and necropsied. histopathologic findings included chorioretinitis, optic neuritis, and encephalitis characterized by mononuclear perivascular infiltration. attempts to prove an infectious cause were unsuccessful.19892722665
the effects of amphetamine on synaptic plasticity in rat's medial prefrontal cortex.morphometric analysis of medial prefrontal cortex (layer vi) of rats treated daily with amphetamine in a dose of 2.5 mg/kg during 3 weeks was performed on the electron microscopic level. the efficacy of the amphetamine dosage was tested on behavioral observation. synapses on dendritic shafts and spines were studied. the density of axo-dendritic synapses increase on 74%, while the density of synapses on spine's neck decreased on 53%. most synaptic parameters measured in axo-dendritic (1) and axo- ...19892723411
can the family physician avoid conflict of interest in the gatekeeper role? an affirmative view. 20002723596
role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures.1. focal electrographic seizures arose in the ca1 region of rat hippocampal slices bathed in elevated (8.5 mm) external potassium [( k+]o). high [k+]o also induced spontaneous interictal bursts that originated in area ca3 and propagated to ca1. to examine the contribution to electrographic seizure initiation of excitatory mechanisms that are influenced by extracellular volume, we studied the effect of hyperosmotic expansion of interstitial volume on seizure occurrence, interictal bursts, and exc ...19892723735
how accurate are faculty evaluations of clinical competence?to determine the degree and sources of variability faculty evaluations of residents for the american board of internal medicine (abim) clinical evaluation exercise (cex).20092723833
synthesis and biological evaluation of s-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase.as part of a continuing search for specific inhibitors of the enzymes involved in polyamine biosynthesis, we have designed and synthesized a multisubstrate adduct inhibitor, s-adenosyl-1,12-diamino-3-thio-9-azadodecane (adodatad), in which critical portions of the nucleophilic aminopropyl acceptor are covalently linked to critical portions of the electrophilic aminopropyl donor to form a potent and specific inhibitor of spermine synthase. in addition, the corresponding desamino analogue which wa ...19892724300
identification of some antigenically related outer-membrane proteins of strains of vibrio cholerae o1 and non-o1 serovars involved in intestinal adhesion and the protective role of antibodies to them.outer-membrane proteins (omps) of vibrio cholerae strains of o1 and non-o1 serovars were studied. marked similarity was found in the omp profiles of different v. cholerae o1 strains but the omp profile of a non-o1 strain was somewhat different. antigenic relatedness between the omps of different v. cholerae strains was established by enzyme-linked immunosorbent assay (elisa). immunoblotting experiments demonstrated that at least two omps of 36 and 25-26 kda were immunogenic and common to strains ...19892724325
incidence of local complications after intramedullary nailing and after plate fixation of femoral shaft fractures.a consecutive series of 378 patients with 381 acute adult femoral shaft fractures in previously intact femora admitted during a 10-year period was reviewed for the incidence of local complications including malunion. the majority, 282 fractures (74%), were caused by motor vehicle accidents. the median age of the patients was 28 years. the policy of management was internal fixation of the fracture on the day of admission. the method of treatment was intramedullary nailing (küntscher or interlocki ...20092724381
[current status of imported infectious diseases and control policy of the ministry of health and welfare]. 19892724553
[incidence of cholera outbreaks in the world: distribution in the environment and imported seafoods]. 19892724570
alterations in offspring behavior induced by chronic prenatal cocaine dosing.sperm-positive female long-evans hooded rats were dosed subcutaneously with 10 mg/kg/day cocaine or an equal volume of vehicle (0.9% sterile saline) from gestation day 4 (gd4) through gd18. offspring were assessed for development of negative geotaxis, righting reflex, spontaneous alternation, and open field activity, and for adult behaviors including drl-20 acquisition, water maze, visual discrimination, barbiturate sleep time, shuttlebox avoidance, footshock sensitivity, and tail flick latency. ...19892725438
primary structures of cytochrome p-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome p-450 gene subfamily ivb.the primary structure of rabbit cytochrome p-450 isozyme 5 has been derived from the nucleotide sequence of cloned cdna. identical sequences were obtained for cdnas constructed with mrna from four different sources, lung and liver of untreated rabbits and liver from rabbits treated once or four times with phenobarbital. isozyme 5 shows significant sequence identity only with rabbit p-450p2 (54%) and rat p-450la omega (53%), which places it in a previously unrecognized cytochrome p-450 gene subfa ...19892725471
tetrahydroaminoacridine and other allosteric antagonists of hippocampal m1 muscarine receptors.tetrahydroaminoacridine (tha) and a variety of other nonclassical antagonists of muscarine receptors were studied for their ability to bind to primary and allosteric sites on muscarine receptors in rabbit hippocampal membranes. competition curves between 13 antagonists and 1 nm [3h]pirenzepine (kd = 3 nm) were simple mass action curves, but tha produced steeper curves, indicating positive cooperativity. nonetheless, tha inhibited the binding of low concentrations of [3h]pirenzepine, [3h]n-methyl ...19892725474
electrophoretic analysis of histoplasma capsulatum chromosomal dna.seven chromosome-sized dna molecules in the downs strain of histoplasma capsulatum were resolved by using chromosome-specific dna probes in blot hybridizations of contour-clamped homogeneous electric field (chef) and field-inversion gel electrophoresis (fige) agarose gels. the sizes of the chromosomal dna bands extended from that of the largest saccharomyces cerevisiae chromosome to beyond that of the schizosaccharomyces pombe chromosomes. under our experimental conditions, the order of the five ...19892725508
characterization and purification of h1tf2, a novel ccaat-binding protein that interacts with a histone h1 subtype-specific consensus element.definition of mechanisms regulating human histone h1 gene transcription during the cell cycle requires the isolation and biochemical characterization of protein factors which interact with specific promoter elements. two distinct binding activities have been identified in nuclear extracts from hela cells and mapped within a 180-base-pair (bp) region of a cell cycle-regulated h1 gene promoter. h1tf1 bound to an h1-specific a + c-rich sequence (ac box), 100 bp upstream of the cap site; h1tf2 inter ...19892725515
myopathy and accumulation of amiodarone. 20092725579
primary structures of sm31/32 diagnostic proteins of schistosoma mansoni and their identification as proteases.we have constructed cdna clones containing the complete nucleotide sequences coding for two highly antigenic schistosoma mansoni adult worm proteins, sm31 and sm32. the predicted amino acid sequence of sm31 shows significant homology to mouse, rat and human cathepsin b. the nucleotide sequence of sm32 is identical to that reported by others for s. mansoni "haemoglobinase'. the different nucleotide sequences demonstrate the existence of two different proteolytic enzymes, both of which are synthes ...19892725581
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 24-1989. a 77-year-old man with back pain and acute inability to walk. 19892725601
pattern of malformations in the children of women treated with carbamazepine during pregnancy.in an attempt to determine whether and to what extent carbamazepine is teratogenic, we evaluated eight children whom we identified retrospectively as having had prenatal exposure to carbamazepine alone or in combination with a variety of anticonvulsants other than phenytoin. in addition, in a prospective study, we documented the outcome of the pregnancies of 72 women who contacted us early in pregnancy because they were concerned about the potential teratogenicity of carbamazepine. a pattern of ...20092725616
the residency years. 20092725620
industrial marketing and medical ethics. 20092725621
a child with phenotypic laron dwarfism and normal somatomedin levels. 20092725626
effects of reserpine on dopamine metabolite in the nucleus accumbens and locomotor activity in freely moving rats.the effect of reserpine (2 mg/kg i.p.) on both locomotor activity and the turnover of dopamine metabolite in the rat nucleus accumbens was estimated by using an activity monitor (animex) and by in vivo brain microdialysis. three to five hours after reserpine administration locomotor activity was reduced and there was a concomitant increase in the level of the dopamine metabolite, homovanillic these findings suggest that depletion of dopamine from the nucleus accumbens may result in decreased loc ...19892725828
the battered nurse executive. 20072725981
electrical and mechanical properties of spontaneous contraction in hypertensive rat portal vein.contractile and electrical activities of longitudinal smooth muscle of portal vein from normotensive wistar kyoto rats (wky) and stroke-prone spontaneously hypertensive rats (shrsp) were compared. amplitude and duration of spontaneous contraction of shrsp portal vein were greater than those of wky portal vein. no significant differences were observed in the resting membrane potentials between these preparations. spontaneous spike activity appeared as a form of bursts. duration of the burst and t ...19892726435
[the best ways of the control of inflammatory diseases of the lung].three approaches to optimal control of inflammatory diseases of the lungs are described. the first approach includes improvement of the diagnostic procedure. the second approach is based on development of new complexes of drug therapy and organization of nondrug therapy. the third approach is prophylactic. the main goals of the approaches are formulated.20092726713
discussion of diffusion of medical innovations. 20092726946
conjugated diene production after airway acid aspiration. 19892726984
molindone: effects in pigeons responding under conditional discrimination tasks.pigeons were trained to respond under three conditional discrimination procedures; 1) a fixed-consecutive-number procedure with (fcn 8-sd) and without (fcn 8) an added external discriminative stimulus, 2) a delayed matching-to-sample (dmts) procedure using 0-sec, 2-sec and 8-sec delay intervals, and 3) a repeated acquisition of behavioral chains (ra) procedure using a four-link response chain with three stimulus keys. the atypical neuroleptic agent molindone decreased accuracy under the fcn 8 at ...20092727003
[aerosol therapy (3). the ultrasonic nebulizer]. 20092727484
[minimal osteosynthesis of fractures of the head of the humerus. indications, technic, results].between 1983 and 1987 minimal osteosynthesis for proximal humeral fractures was performed in 30 patients, 23 women and 7 men, with an average age of 58.5 years. according to the neer classification there were 10 two-part, 9 three-part and 11 four-part fractures. internal fixation was achieved with kirschner wire (n = 9), cancellous screws (n = 4) or tension band (n = 17). the technique of internal fixation with kirschner wire and lateral tension band is described. follow-up examination was possi ...20092727711
[use of the dna-dna hybridization method on filters for determining the toxic potency of atypical strains of vibrio cholerae isolated from natural sources].the methods of the radioimmunoassay and the blot hybridization of restricted fragments of chromosomal dna have been used for the characterization of v. cholerae atypical strains isolated from the natural environment. for all strains under study, the radioimmunoassay has been found to yield the most sharply defined data characterizing their atoxigenicity. the absence of the structural genes of toxin in the chromosomes of these strains has been shown by the method of blot hybridization. some metho ...19892728700
distribution of different fiber types in whole cross-sections of human platysma. a histological and morphometric study.analysis of cryostat cross-sections of the entire platysma muscle from human autopsies revealed enzyme histochemical and morphometric differences between normal human limb and facial muscles. the mean diameter of platysma fibers was about 50% of that of normal limb muscle fibers. fiber type diameter increased from the medial to the lateral parts of the platysma. a variability coefficient of 356 indicated great variation in fiber caliber, with many fibers of 10 microns and less. type i fibers sho ...19892728841
correction of microcytosis following elimination of an occult source of aluminum contamination of dialysate.a higher prevalence of aluminum-associated microcytic anemia was noted in hemodialysis unit a (n = 67) compared to unit b (n = 39). this finding could not be explained by differences in the aluminum content of reverse osmosis (ro) water or intake of antacids containing aluminum by patients in the two units. an intermittent source of aluminum contamination was suspected when water aluminum and total dissolved solutes (tds) were measured at several sites in the water treatment facility of unit a. ...20092729267
negative ion fast atom bombardment mass spectrometry for native gangliosides using a neutral matrix.a hexamethylphosphoric triamide proved to be a useful solvent for negative ion fast atom bombardment mass spectrometry (fabms) of underivatized gangliosides, using a conventional glycerol matrix. analysis of the gangliosides using a hexamethylphosphoric triamide was more convenient and more efficient not only for molecular weight determination but also for elucidating the structure of the carbohydrate sequence. we also noted the significance of the high polarity of the solvent as well as the ele ...19892729549
negative ion fast atom bombardment mass spectrometry for native gangliosides using a neutral matrix.a hexamethylphosphoric triamide proved to be a useful solvent for negative ion fast atom bombardment mass spectrometry (fabms) of underivatized gangliosides, using a conventional glycerol matrix. analysis of the gangliosides using a hexamethylphosphoric triamide was more convenient and more efficient not only for molecular weight determination but also for elucidating the structure of the carbohydrate sequence. we also noted the significance of the high polarity of the solvent as well as the ele ...19892729549
low nanogram detection of nucleotides using fast atom bombardment-mass spectrometry.the effect of trimethylsilyl (tms) derivatization on detection limits of mononucleotides in fast atom bombardment-mass spectrometry (fab-ms) was examined. fab-ms methods were developed to optimize sensitivity using adenosine 5'-monophosphate as a model compound and then applied to reference standards of two clinically important nucleotides: tricyclic nucleoside-5'-monophosphate (tcnmp) and 5-fluoro-2'-deoxyuridine-5'-monophosphate (fdump). the detection limit for the tms derivative of tcnmp was ...20092729562
[round table on the current status of vascular surgery]. 20092729653
isoelectric focusing under dissociating conditions for analysis of muscle protein from clinically normal dogs and labrador retrievers with hereditary myopathy.protein profiles of whole homogenates of anconeus (slow twitch) and biceps femoris (fast twitch) muscles of clinically normal dogs and of labrador retrievers with hereditary myopathy (hm) were resolved on flat bed polyacrylamide isoelectric-focusing gels. three methods of sample solubilization were performed. the solubilization buffer, with high concentrations of urea, precipitated the zwitterionic detergent, but use of the buffer containing 3% np-40, 9.2m urea, and 0.1m arginine resulted in bet ...19892729710
breast volume measurement of 598 women using biostereometric analysis.a study of the volumes of the right and left breasts of 598 subjects was undertaken using biostereometric analysis. this measurement uses close-range stereophotogrammetry to characterize the shape of the breast, and is noncontact, noninvasive, accurate, and rapid with respect to the subject involvement time. using chi-square tests, volumes and volumetric differences between breast pairs were compared with handedness, perception of breast size by each subject, age, and menstrual status. no signif ...20092729845
importance of intercellular lipids in water-retention properties of the stratum corneum: induction and recovery study of surfactant dry skin.in order to further clarify the role of intercellular lipids in the water-retention properties of the stratum corneum, forearm skin of six healthy male volunteers was treated with 5% sodium dodecyl sulfate (sds) for 1, 10, and 30 min. all treatment periods induced chapping and scaling of the stratum corneum without any inflammatory reaction, accompanied by a significant decrease in its water-retention function. electron-microscopic analysis of sds-treated stratum corneum revealed selective deple ...20092730142
large phosphate shifts with treatment for hyperglycemia.although hypophosphatemia is known to commonly accompany therapy for hyperglycemia, it is not generally appreciated that severe life-threatening depletion of phosphate may occur. i followed up two patients who had precipitous drops during intravenous insulin therapy for diabetic ketoacidosis and hyperosmolar nonketotic state. the patient with diabetic ketoacidosis had a phosphate level nadir that equaled the lowest recorded phosphate level in a living human (0.03 mmol/l). because (1) serum phosp ...19892730261
benign clear cell ('sugar') tumor of lung. 20022730283
[the place of provisional tissues in the histologic classification, used for pedagogical purposes]. 20092730350
relationship of muscle strength of back and upper extremity with level of physical activity in healthy women.the objective of this study was to evaluate any correlation between the muscle strength of the upper extremity (appendicular muscles) and that of the back extensors (axial muscles) in postmenopausal women. back extensor strength and power grip of the dominant hand were measured in 68 healthy postmenopausal women. the level of physical activity was determined according to a scale (score, 0-18) that considered vocational and avocational activities. statistical analysis demonstrated a significant p ...20092730781
in vivo dna cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse l1210 leukemia and normal bone marrow cells.alkaline elution was done on a variety of cells following cyclophosphamide (cy) treatment in vivo. cells used were l1210 leukemia, normal mouse bone marrow, and peripheral blood cells obtained from a patient with chronic lymphatic leukemia (cll). endpoints used were determination of single strand breaks, dna-dna interstrand and dna-protein cross-links. after treatment of mice with cy (4 mg/mouse), low levels of single strand breaks were observed in both l1210 leukemia and cdf1 normal bone marrow ...19892731167
age-related induction and disappearance of carcinogen-dna-adducts in livers of rats exposed to low levels of 2-acetylaminofluorene.it was investigated whether in vivo aging of rat liver is associated with changes in the induction and rate of disappearance of dna damage. for this purpose 6- and 36-month-old rats were intraperitoneally injected with a single, low dose (5 mg/kg body wt.) of the model liver carcinogen 2-acetylaminofluorene (aaf). using the 32p-postlabeling assay we found that n-(deoxyguanosin-8-yl)-2-aminofluorene (dg-c8-af) was the major dna-adduct formed. the minor adduct n-(deoxyguanosin-8-yl)-2-acetylaminof ...19892731307
localization of adriamycin in model and natural membranes. influence of lipid molecular packing.the interaction of adriamycin with lipids was studied in model (monolayers, small unilamellar vesicles, large multilamellar vesicles) and natural (chinese hamster ovary cell) membranes by measurement of fluorescence energy transfer and fluorescence quenching. 2-apam, 7-aste, 12-aste and anthracene-phosphatidylcholine were used as fluorescent probes in which the anthracene group is well located at graded depths in the membrane. egg-yolk phosphatidylcholine and a 1/1 mixture of it with bovine brai ...19892731543
isolation and structure of two novel 6-kda dimeric peptides from the corpora cardiaca of the insect locusta migratoria. molecular mass determination by mass spectrometry.we have isolated two major 6-kda peptides from extracts of corpora cardiaca of adult females of locusta migratoria. these peptides have been characterized by peptide sequencing and liquid secondary-ion mass spectrometry. they are structurally related dimers, one (6278.5 da) being a homodimer (a-a chains), the other (6280.5 da) being a heterodimer (a-b chains). a 60% similarity exists between the a and b chains. both peptides have been chemically synthesized and the synthetic compounds appeared t ...20092731552
comparison of the reactivities and immunogenicities of procholeragenoid and the b subunit of cholera toxin in thai volunteers.procholeragenoid, a stable high-molecular-weight aggregate of cholera toxin derived by heat treatment, was evaluated for reactivity and immunogenicity in adult thai volunteers. since procholeragenoid is known to retain some residual activity of cholera toxin, increasing amounts were ingested until diarrhea occurred; 250 micrograms induced diarrhea, but 100 micrograms did not. procholeragenoid and cholera toxin b subunit, both in 100-micrograms amounts, were then compared for systemic and intesti ...19892731977
milk plasma supports growth and differentiation of a mouse teratocarcinoma cell line. 19892732192
heterogeneic expression of blood group a and h isoantigens in bladder tumors: association with nuclear volume.intratumor heterogeneity is a major problem in immunodiagnosis and treatment of carcinomas. to elucidate the well-known heterogeneity in transitional-cell carcinomas of the ability to express blood group abo isoantigens, a stereological estimate of the mean nuclear volume in areas expressing blood group antigens was compared to the estimate from areas of identical pathological grade at which antigen expression was deleted. four microscopic fields were examined from antigen-positive and four from ...20022732458
improved procedure for preparation of f(ab')2 fragments of mouse iggs by papain digestion.preparation of f(ab')2 fragments from mouse monoclonal igg by papain digestion can result in incorporation of traces of papain into antibody fragments by disulfide exchange. such trace contamination can have detrimental effects on the integrity of these antibody fragments following reduction. gel filtration and ion exchange chromatography procedures did not eliminate papain contamination from f(ab')2 preparations. the use of antibody specific for papain to remove this contamination from f(ab')2 ...19892732475
vibrio cholerae o1 adherence to human small intestinal m cells in vitro. 19892732514
[a case report of aortic and mitral regurgitation combined with ankylosing spondylosis].the purpose of this communication is to present a successful case of surgical treatment of aortic and mitral valve regurgitation associated with ankylosing spondylosis. a 48-year-old male was admitted with symptoms of palpitation and shortness of breath. his heart murmur had been pointed out for 4 months prior to this admission. his previous history did not show any evidence of rheumatic heart disease. retrograde aortography showed moderate to severe aortic valvular regurgitation and echocardiog ...20022732540
[a case of coexisting descending thoracic aortic aneurysm and atypical aortic coarctation treated successfully by surgery using the thromboexclusion method].the thromboexclusion method was successfully applied to a 43-year-old male with aortitis syndrome. preoperative aortogram showed a fusiform aneurysm of the descending aorta just below the left subclavian artery and atypical coarctation of the descending aorta distal to this aneurysm. pressure gradient across the stenosis was about 70 mmhg. the technique of flow reversal and thromboexclusion was performed in this patient because of severe calcification in the aortic arch and the entire descending ...20022732543
[microfilaments and intermediate filaments in the fetal capillary endothelial cells of the human chorionic villi--ultrastructural and immunohistochemical study].augmentation of cytoskeletons in fetal capillary endothelial cells is one of the well known pathologic changes in toxemic placentae. but we can find very few reports on these filaments in placentae, especially on their ontogeny. an ultrastructural study on human chorionic villi from 55 normal and 25 toxemic pregnancies, covering all periods of gestation, revealed that endothelial cells already had a small amount of intermediate filaments and microfilaments from 6 weeks' gestation and that they g ...19892732559
turning off the diarrhea: the role of food and ors.ninety-three boys aged 5 years or less who had diarrhea due to vibrio cholerae were randomly assigned to treatment with glucose oral rehydration salt (ors) or rice-based ors. for the first 24 h, ors only was given to all the patients. during the next 24 h, ors and normal food were given. the efficacy of the two types of ors was compared in terms of ors intake, stool output, change in hematocrit reading, serum specific gravity, and increase in body weight. at the end of the first 24 h of treatmen ...19892732867
neurolathyrism remains a threat in india. 20082733776
neurolathyrism remains a threat in india. 20082733776
parietaria. a newly identified cause of pollen allergy in california. 20082735045
kinetic experiments with radionuclides concerning the perilymph-blood barrier in a guinea pig model.since 1950 many animal radiotracer experiments have been performed to study inner ear kinetics. for the most part in these studies, radionuclides were applied systemically, following which a discontinuous probing of inner ear fluids or of inner ear tissues was done. two techniques have been developed in the section for experimental otorhinolaryngology of the university of würzburg. these have been adapted to the direct and continuous measurements of inner ear efflux kinetics for several hour per ...19892735826
allyl alcohol-induced hemolysis and its relation to iron release and lipid peroxidation.allyl alcohol administration to starved mice produced, along with liver necrosis, a high incidence (about 50%) of hemolysis. a marked decrease in erythrocyte glutathione (gsh) was seen in all the intoxicated animals. such a decrease was significantly higher in the animals showing hemolysis. in these animals a substantial amount of malonic dialdehyde (mda) was detected in plasma and a marked decrease in arachidonic and docosahexaenoic acids was found in erythrocyte phospholipids. these data sugge ...19892735939
late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture.an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ...20082736550
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