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antifungal activities of seven west african combretaceae used in traditional medicine.seven species of combretaceae were investigated for their antifungal activity against the pathogenic fungi candida albicans, epidermophyton floccosum, microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum. pteleopsis suberosa and terminalia avicennioides appear to be the most active plants. phytochemical screening shows that these plants are particularly rich in tannins and saponins, which might be responsible for their antifungal activity.199910473181
antifungal activities of seven west african combretaceae used in traditional medicine.seven species of combretaceae were investigated for their antifungal activity against the pathogenic fungi candida albicans, epidermophyton floccosum, microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum. pteleopsis suberosa and terminalia avicennioides appear to be the most active plants. phytochemical screening shows that these plants are particularly rich in tannins and saponins, which might be responsible for their antifungal activity.199910473181
dermatophyte infections in free-ranging florida panthers (felis concolor coryi).three free-ranging florida panthers (felis concolor coryi) were diagnosed with clinical dermatophytosis; two were infected with trichophyton mentagrophytes, and one was infected with microsporum gypseum. two of these panthers were juvenile males that were diagnosed with focal to focally coalescing dermatophytosis; one caused by m. gypseum and the other by t. mentagrophytes. these animals were not treated, and clinical signs resolved spontaneously over 6 mo. the third panther, an adult male from ...199910484147
dermatophyte infections in free-ranging florida panthers (felis concolor coryi).three free-ranging florida panthers (felis concolor coryi) were diagnosed with clinical dermatophytosis; two were infected with trichophyton mentagrophytes, and one was infected with microsporum gypseum. two of these panthers were juvenile males that were diagnosed with focal to focally coalescing dermatophytosis; one caused by m. gypseum and the other by t. mentagrophytes. these animals were not treated, and clinical signs resolved spontaneously over 6 mo. the third panther, an adult male from ...199910484147
in vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes.thirty-four arylpropanoids and related compounds were evaluated in vitro for antifungal properties. among them, 22 phenyl-, 4 naphthyl-, and 4 phenanthrylpropanoids; naphthalene; phenanthrene; and 2-chloro-1-hexyl-1-propanone were tested against dermatophytes by the agar dilution method. alpha-halopropiophenones exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum, with mic values b ...199910543891
in vitro evaluation of antifungal properties of phenylpropanoids and related compounds acting against dermatophytes.thirty-four arylpropanoids and related compounds were evaluated in vitro for antifungal properties. among them, 22 phenyl-, 4 naphthyl-, and 4 phenanthrylpropanoids; naphthalene; phenanthrene; and 2-chloro-1-hexyl-1-propanone were tested against dermatophytes by the agar dilution method. alpha-halopropiophenones exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum, with mic values b ...199910543891
epidemiology of dermatomycoses of humans in central poland. part v. tinea corporis.the total number of dermatophytoses (7393) included 2204 (29.8%) cases of tinea glabrosa. etiological factors in descending order were: microsporum canis (23.5%), trichophyton mentagrophytes var. granulosum (21.6%), trichophyton rubrum (17.8%), trichophyton tonsurans (10.4%), epidermophyton floccosum (7.7%), t. mentagrophytes var. quinckeanum (6.0%), microsporum gypseum (5.3%), trichophyton violaceum (3.7%), t. mentagrophytes var. interdigitale (2.3%), microsporum equinum (0.7%), trichophyton ve ...199910680444
epidemiology of dermatomycoses of humans in central poland. part v. tinea corporis.the total number of dermatophytoses (7393) included 2204 (29.8%) cases of tinea glabrosa. etiological factors in descending order were: microsporum canis (23.5%), trichophyton mentagrophytes var. granulosum (21.6%), trichophyton rubrum (17.8%), trichophyton tonsurans (10.4%), epidermophyton floccosum (7.7%), t. mentagrophytes var. quinckeanum (6.0%), microsporum gypseum (5.3%), trichophyton violaceum (3.7%), t. mentagrophytes var. interdigitale (2.3%), microsporum equinum (0.7%), trichophyton ve ...199910680444
purification and characterization of camp dependent protein kinase from microsporum gypseum.a cyclic amp dependent protein kinase (pka), its regulatory (r) and catalytic (c) subunits were purified to homogeneity from soluble extract of microsporum gypseum. purified enzyme showed a final specific activity of 277.9 nmol phosphate transferred min(-1) mg protein(-1) with kemptide as substrate. the enzyme preparation showed two bands with molecular masses of 76 kda and 45 kda on sodium dodecyl polyacrylamide gel electrophoresis. the 76 kda subunit was found to be the regulatory (r) subunit ...200010699496
purification and characterization of camp dependent protein kinase from microsporum gypseum.a cyclic amp dependent protein kinase (pka), its regulatory (r) and catalytic (c) subunits were purified to homogeneity from soluble extract of microsporum gypseum. purified enzyme showed a final specific activity of 277.9 nmol phosphate transferred min(-1) mg protein(-1) with kemptide as substrate. the enzyme preparation showed two bands with molecular masses of 76 kda and 45 kda on sodium dodecyl polyacrylamide gel electrophoresis. the 76 kda subunit was found to be the regulatory (r) subunit ...200010699496
tinea incognito due to microsporum gypseum in three children.tinea incognito is a dermatophytosis of atypical clinical character due to the absence of classic features of ringworm. it is caused by prolonged use of topical steroids, sometimes prescribed as a result of incorrect diagnosis. the cases reported in the literature have different clinical presentations and have generally been in adults. we report three children with tinea incognito in whom the lesions were psoriasis-like, eczema-like, and lichenoid, respectively. diagnosis was confirmed by mycolo ...200010720987
tinea incognito due to microsporum gypseum in three children.tinea incognito is a dermatophytosis of atypical clinical character due to the absence of classic features of ringworm. it is caused by prolonged use of topical steroids, sometimes prescribed as a result of incorrect diagnosis. the cases reported in the literature have different clinical presentations and have generally been in adults. we report three children with tinea incognito in whom the lesions were psoriasis-like, eczema-like, and lichenoid, respectively. diagnosis was confirmed by mycolo ...200010720987
dermatophytosis in red pandas (ailurus fulgens fulgens): a review of 14 cases.fourteen cases of dermatophytosis were identified from medical records of red pandas (ailurus fulgens fulgens) housed at the knoxville zoo between 1980 and 1996. the median age of affected animals on initial presentation was 8.5 wk (3 wk-11 mo). clinical signs included crusting, purulent exudate, alopecia, thickening of affected skin, ulceration, and necrosis. seven animals had mild lesions with signs restricted to crusting and/or alopecia, and six animals had more severe infections, with ulcera ...199910749446
dermatophytosis in red pandas (ailurus fulgens fulgens): a review of 14 cases.fourteen cases of dermatophytosis were identified from medical records of red pandas (ailurus fulgens fulgens) housed at the knoxville zoo between 1980 and 1996. the median age of affected animals on initial presentation was 8.5 wk (3 wk-11 mo). clinical signs included crusting, purulent exudate, alopecia, thickening of affected skin, ulceration, and necrosis. seven animals had mild lesions with signs restricted to crusting and/or alopecia, and six animals had more severe infections, with ulcera ...199910749446
efficacy of chlorhexidine against some strains of cultured and clinically isolated microorganisms.the efficacy of chlorhexidine digluconate was determined against some strains of collected and clinically isolated bacteria and fungi. the efficacy was evaluated either by calculating a minimum inhibitory concentration (mic) or by efficacy trials according to the guidelines of the european committee for standardization. the mic values of chlorhexidine for staphylococcus aureus, microsporum gypseum, microsporum canis and trichophyton mentagrophytes were 0.625 microg/ml, 12.5 microg/ml, 50 microg/ ...200010836268
efficacy of chlorhexidine against some strains of cultured and clinically isolated microorganisms.the efficacy of chlorhexidine digluconate was determined against some strains of collected and clinically isolated bacteria and fungi. the efficacy was evaluated either by calculating a minimum inhibitory concentration (mic) or by efficacy trials according to the guidelines of the european committee for standardization. the mic values of chlorhexidine for staphylococcus aureus, microsporum gypseum, microsporum canis and trichophyton mentagrophytes were 0.625 microg/ml, 12.5 microg/ml, 50 microg/ ...200010836268
antifungal effects of hydrolysable tannins and related compounds on dermatophytes, mould fungi and yeasts.a series of hydrolysable tannins and related compounds was evaluated for antifungal activities against filamentous fungi (epidermophyton floccosum; microsporum canis; microsporum gypseum; trichophyton mentagrophytes; trichophyton rubrum; trichophyton tonsurans; trichophyton terrestre; penicillium italicum; aspergillus fumigatus; mucor racemosus; rhizopus nigricans) and opportunistic yeasts (candida albicans; candida glabrata; candidata krusei; cryptococcus neoformans), using the agar dilution me ...200010928561
antifungal effects of hydrolysable tannins and related compounds on dermatophytes, mould fungi and yeasts.a series of hydrolysable tannins and related compounds was evaluated for antifungal activities against filamentous fungi (epidermophyton floccosum; microsporum canis; microsporum gypseum; trichophyton mentagrophytes; trichophyton rubrum; trichophyton tonsurans; trichophyton terrestre; penicillium italicum; aspergillus fumigatus; mucor racemosus; rhizopus nigricans) and opportunistic yeasts (candida albicans; candida glabrata; candidata krusei; cryptococcus neoformans), using the agar dilution me ...200010928561
microsporum gypseum complex in madras, india.in madras, india, 312 soil samples were collected from different habitats and screened for the presence of keratinophilic fungi especially those belonging to the microsporum gypseum complex.200010948815
microsporum gypseum complex in madras, india.in madras, india, 312 soil samples were collected from different habitats and screened for the presence of keratinophilic fungi especially those belonging to the microsporum gypseum complex.200010948815
presence of keratinophilic fungi with special reference to dermatophytes on the haircoat of dogs and cats in méxico and nezahualcoyotl cities.in order to study the presence of keratinophilic fungi with special reference to dermatophytes on the coat of dogs and cats living in the cities of mexico and nezahualcoyotl in the metropolitan area of mexico city, two hundred samples were collected from dogs and one hundred from cats by using the mackenzie's tooth brush technique, they were processed by routine mycological methods for dermatophyte fungi, results were analyzed by means of the statistical packages sas. there were isolated 67 and ...200010948828
presence of keratinophilic fungi with special reference to dermatophytes on the haircoat of dogs and cats in méxico and nezahualcoyotl cities.in order to study the presence of keratinophilic fungi with special reference to dermatophytes on the coat of dogs and cats living in the cities of mexico and nezahualcoyotl in the metropolitan area of mexico city, two hundred samples were collected from dogs and one hundred from cats by using the mackenzie's tooth brush technique, they were processed by routine mycological methods for dermatophyte fungi, results were analyzed by means of the statistical packages sas. there were isolated 67 and ...200010948828
antimicrobial activity of extracts of eastern north american hardwood trees and relation to traditional medicine.wood and bark extracts of 14 eastern north american hardwood tree species which were used traditionally as medicine by first nation's people were screened for antimicrobial activities with eight strains of bacteria and six strains of fungi. eighty-six percent of the bark extracts were active against methicillin sensitive staphylococcus aureus; 71% against bacillus subtilus and 79% against mycobacterium phlei. the bark extract of juglans cinerea was active against pseudomonas aeruginosa 187, salm ...200011025152
antimicrobial activity of extracts of eastern north american hardwood trees and relation to traditional medicine.wood and bark extracts of 14 eastern north american hardwood tree species which were used traditionally as medicine by first nation's people were screened for antimicrobial activities with eight strains of bacteria and six strains of fungi. eighty-six percent of the bark extracts were active against methicillin sensitive staphylococcus aureus; 71% against bacillus subtilus and 79% against mycobacterium phlei. the bark extract of juglans cinerea was active against pseudomonas aeruginosa 187, salm ...200011025152
antifungal activity of extracts from medicinal plants used by first nations peoples of eastern canada.from literature describing medicinal usage of plants by first nations peoples in eastern canada, 18 eastern canadian plants were selected and tested for their antifungal activities. eight randomly selected tropical plants were also tested for comparative purposes. four groups of plants were obtained: popular antimicrobial-remedy (n=6), popular non-antimicrobial-remedy (n=6), random temperate (n=6) and random tropical (n=8). extracts from these plants were tested in disk assays as growth inhibito ...200011025156
antifungal activity of extracts from medicinal plants used by first nations peoples of eastern canada.from literature describing medicinal usage of plants by first nations peoples in eastern canada, 18 eastern canadian plants were selected and tested for their antifungal activities. eight randomly selected tropical plants were also tested for comparative purposes. four groups of plants were obtained: popular antimicrobial-remedy (n=6), popular non-antimicrobial-remedy (n=6), random temperate (n=6) and random tropical (n=8). extracts from these plants were tested in disk assays as growth inhibito ...200011025156
keratinopathogenic mould fungi and dermatophytes in healthy and diseased hooves of horses.specimens of hoof horn from 187 horses were examined for a possible relationship between clinically affected hooves and the occurrence of pathogenic fungi. specimens were taken from the coronary band and from the stratum externum and medium of the coronary horn and transferred on to sabouraud dextrose agar, with and without cycloheximide, and incubated at 28 degrees c. dermatophytes and mould fungi were identified by their macroscopic and microscopic characteristics. the 732 isolates could be as ...200011128074
keratinopathogenic mould fungi and dermatophytes in healthy and diseased hooves of horses.specimens of hoof horn from 187 horses were examined for a possible relationship between clinically affected hooves and the occurrence of pathogenic fungi. specimens were taken from the coronary band and from the stratum externum and medium of the coronary horn and transferred on to sabouraud dextrose agar, with and without cycloheximide, and incubated at 28 degrees c. dermatophytes and mould fungi were identified by their macroscopic and microscopic characteristics. the 732 isolates could be as ...200011128074
in vitro antifungal activity of schizozygia coffaeoides bail. (apocynaceae) extracts.leaf extracts of schizozygia coffaeoides were investigated for antifungal activity using the disc diffusion assay technique. petroleum ether 40-60 degrees c, dichloromethane-ethyl acetate (1:1) and methanol extracts were fungitoxic to trichophyton mentagrophytes, microsporum gypseum, cladosporium cucumerinum and candida albicans. the extracts were fungistatic in action.200111137346
in vitro antifungal activity of schizozygia coffaeoides bail. (apocynaceae) extracts.leaf extracts of schizozygia coffaeoides were investigated for antifungal activity using the disc diffusion assay technique. petroleum ether 40-60 degrees c, dichloromethane-ethyl acetate (1:1) and methanol extracts were fungitoxic to trichophyton mentagrophytes, microsporum gypseum, cladosporium cucumerinum and candida albicans. the extracts were fungistatic in action.200111137346
zoophilic and geophilic dermatophytoses among farmers and non-farmers in eastern poland.the study was aimed at assessing the frequency of zoophilic and geophilic fungal infections among farmers compared to non-farmers in eastern poland. the study was carried out on adult patients with a suspicion of fungal infection of skin or its appendages. skin scrapings or nail fragments were cultured on sabouraud agar with chloramphenicol and cycloheximide for at least 3 weeks, and then identified based on macroscopic and microscopic morphology. in total, 116 subjects were included into the fa ...200011153042
zoophilic and geophilic dermatophytoses among farmers and non-farmers in eastern poland.the study was aimed at assessing the frequency of zoophilic and geophilic fungal infections among farmers compared to non-farmers in eastern poland. the study was carried out on adult patients with a suspicion of fungal infection of skin or its appendages. skin scrapings or nail fragments were cultured on sabouraud agar with chloramphenicol and cycloheximide for at least 3 weeks, and then identified based on macroscopic and microscopic morphology. in total, 116 subjects were included into the fa ...200011153042
natural pathogens of laboratory animals and their effects on research.the natural fungal pathogens of laboratory animals such as rabbits and guinea pigs are mainly dermatophyte species, most commonly trichophyton mentagrophytes and also, less frequently microsporum gypseum and m. canis. however, the incidences of infection and clinical disease are low in well-managed animal facilities. young or immunocompromised rabbits are thought to be most susceptible. dermatophytes infect the epidermis and adnexal structures, including hair follicles and shafts, usually on or ...200011204165
natural pathogens of laboratory animals and their effects on research.the natural fungal pathogens of laboratory animals such as rabbits and guinea pigs are mainly dermatophyte species, most commonly trichophyton mentagrophytes and also, less frequently microsporum gypseum and m. canis. however, the incidences of infection and clinical disease are low in well-managed animal facilities. young or immunocompromised rabbits are thought to be most susceptible. dermatophytes infect the epidermis and adnexal structures, including hair follicles and shafts, usually on or ...200011204165
exocellular enzyme activity of dermatophytes and other fungi isolated from ruminants in southern iraq.sixteen fungal species were isolated from 182 specimens collected from four ruminants (buffalo, camel, cattle and sheep) in southern iraq. fungi represented by five species of dermatophytes and eleven species of other fungi were screened for the activity of four enzymes: keratinase. proteinase, lipase and amylase. keratinase was found to be produced by all of the dermatophytes and non-dermatophytes, except for paecillomyces variottii and scytalidium lignicola. however, high keratinase activity w ...200111407490
exocellular enzyme activity of dermatophytes and other fungi isolated from ruminants in southern iraq.sixteen fungal species were isolated from 182 specimens collected from four ruminants (buffalo, camel, cattle and sheep) in southern iraq. fungi represented by five species of dermatophytes and eleven species of other fungi were screened for the activity of four enzymes: keratinase. proteinase, lipase and amylase. keratinase was found to be produced by all of the dermatophytes and non-dermatophytes, except for paecillomyces variottii and scytalidium lignicola. however, high keratinase activity w ...200111407490
antifungal activities of pelargonic and capric acid on microsporum gypseum.the inhibitory effects of pelargonic and capric acid on microsporum gypseum were examined. solid and liquid sabouraud glucose media containing different concentrations of pelargonic and capric acid were separately prepared and inoculated with the suspension of mycelium and spores of m. gypseum and incubated at 25 degrees c for 1 month. the culture media were examined periodically for fungal growth and the minimum inhibitory concentration (mic) of each fatty acid was determined. the mic for capri ...200111413921
antifungal activities of pelargonic and capric acid on microsporum gypseum.the inhibitory effects of pelargonic and capric acid on microsporum gypseum were examined. solid and liquid sabouraud glucose media containing different concentrations of pelargonic and capric acid were separately prepared and inoculated with the suspension of mycelium and spores of m. gypseum and incubated at 25 degrees c for 1 month. the culture media were examined periodically for fungal growth and the minimum inhibitory concentration (mic) of each fatty acid was determined. the mic for capri ...200111413921
antimicrobial activity of alstonia macrophylla: a folklore of bay islands.the methanolic crude and methanol-aqueous extract of alstonia macrophylla leaves and n-butanol part of the crude extract showed antimicrobial activity against various strains of staphylococcus aureus, staphylococcus saprophyticus, streptococcus faecalis, escherichia coli, proteus mirabilis, trichophyton rubrum, trichophyton mentagrophytes var. mentagrophytes and microsporum gypseum. the minimum inhibitory concentration (mic) values ranges from 64 to 1000 microg/ml for bacteria and 32-128 mg/ml f ...200111483378
antimicrobial activity of alstonia macrophylla: a folklore of bay islands.the methanolic crude and methanol-aqueous extract of alstonia macrophylla leaves and n-butanol part of the crude extract showed antimicrobial activity against various strains of staphylococcus aureus, staphylococcus saprophyticus, streptococcus faecalis, escherichia coli, proteus mirabilis, trichophyton rubrum, trichophyton mentagrophytes var. mentagrophytes and microsporum gypseum. the minimum inhibitory concentration (mic) values ranges from 64 to 1000 microg/ml for bacteria and 32-128 mg/ml f ...200111483378
purification of diacylglycerol kinase from microsporum gypseum and its phosphorylation by the catalytic subunit of protein kinase a.diacylglycerol (dg) kinase (ec 2.7.1.107) was purified to homogeneity from the soluble extract of microsporum gypseum, a dermatophyte. purified enzyme showed a final specific activity of 2172 pmol/min/mg protein and its apparent molecular weight on sds-page was found to be 93 kda. the activity of purified enzyme was inhibited in a dose-dependent manner in the presence of dg-kinase inhibitor (d5919, sigma). dg-kinase activity was found to be stimulated in the presence of phosphatidylcholine, phos ...200111488595
purification of diacylglycerol kinase from microsporum gypseum and its phosphorylation by the catalytic subunit of protein kinase a.diacylglycerol (dg) kinase (ec 2.7.1.107) was purified to homogeneity from the soluble extract of microsporum gypseum, a dermatophyte. purified enzyme showed a final specific activity of 2172 pmol/min/mg protein and its apparent molecular weight on sds-page was found to be 93 kda. the activity of purified enzyme was inhibited in a dose-dependent manner in the presence of dg-kinase inhibitor (d5919, sigma). dg-kinase activity was found to be stimulated in the presence of phosphatidylcholine, phos ...200111488595
application of pcr to distinguish common species of dermatophytes.this report describes the application of pcr fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (gaca)(4). the primer was able to amplify all the strains, producing species-specific profiles for microsporum canis, microsporum gypseum, trichophyton rubrum, trichophyton ajelloi, and epidermophyton floccosum. intraspecific variability was not observed for these species. instead, ...200111526185
application of pcr to distinguish common species of dermatophytes.this report describes the application of pcr fingerprinting for the identification of species and varieties of common dermatophytes and related fungi utilizing as a single primer the simple repetitive oligonucleotide (gaca)(4). the primer was able to amplify all the strains, producing species-specific profiles for microsporum canis, microsporum gypseum, trichophyton rubrum, trichophyton ajelloi, and epidermophyton floccosum. intraspecific variability was not observed for these species. instead, ...200111526185
microsporum gypseum isolated from a feline case of dermatophytosis.the 1- to 2-month-old female cross-breed cat presented with alopecia, erythema and many crusts were present on the tail. microscopic examination of crusts from the tail disclosed epithelial debris, exudate, mycelium, and arthrospores. microsporum gypseum which is rarely isolated from cats as a causative agent of dermatophytsis was cultured from the crusts on a 1/10 sabouraud glucose agar at 27 degrees c for 1 week. the isolate of m. gypseum from the cat was examined by random amplification of po ...200111714073
microsporum gypseum isolated from a feline case of dermatophytosis.the 1- to 2-month-old female cross-breed cat presented with alopecia, erythema and many crusts were present on the tail. microscopic examination of crusts from the tail disclosed epithelial debris, exudate, mycelium, and arthrospores. microsporum gypseum which is rarely isolated from cats as a causative agent of dermatophytsis was cultured from the crusts on a 1/10 sabouraud glucose agar at 27 degrees c for 1 week. the isolate of m. gypseum from the cat was examined by random amplification of po ...200111714073
atypical tinea corporis caused by microsporum gypseum in a subject with acquired immune deficiency syndrome. 200111730066
atypical tinea corporis caused by microsporum gypseum in a subject with acquired immune deficiency syndrome. 200111730066
human hair colonizing fungi in water sediments of india.out of 144 samples of water sediments, 183 isolates belonging to 9 genera and 22 species were isolated. fifty-nine isolates of acremonium, 26 of chrysosporium indicum, 22 of chrysosporium keratinophilum, 17 of malbranchea sp. and 10 of microsporum gypseum were recovered. acremonium implicatum, chrysosporium georgii, chrysosporium xerophilum and geomyces pannorum were reported for the first time from india.200111761148
human hair colonizing fungi in water sediments of india.out of 144 samples of water sediments, 183 isolates belonging to 9 genera and 22 species were isolated. fifty-nine isolates of acremonium, 26 of chrysosporium indicum, 22 of chrysosporium keratinophilum, 17 of malbranchea sp. and 10 of microsporum gypseum were recovered. acremonium implicatum, chrysosporium georgii, chrysosporium xerophilum and geomyces pannorum were reported for the first time from india.200111761148
proximal subungual hyperkeratosis of the big toe due to microsporum gypseum. 200111800151
proximal subungual hyperkeratosis of the big toe due to microsporum gypseum. 200111800151
dermatophytoses in prague, czech republic, between 1987 and 1998.over a 12-year period, from 1987 to 1998, the spectrum of aetiological agents isolated from 11208 patients (6265 females and 4943 males) suspected of having dermatomycosis was analysed in the mycological laboratory of the department of dermatology, charles university, prague. the most frequently examined locations were toenails (34.9%), feet (15.6%), fingernails (12.8%), toe webs (11%), trunk (10%) and hands (8.7%). dermatophytes were isolated from 5605 (30.2%) of all 18528 samples examined. amo ...200111820263
dermatophytoses in prague, czech republic, between 1987 and 1998.over a 12-year period, from 1987 to 1998, the spectrum of aetiological agents isolated from 11208 patients (6265 females and 4943 males) suspected of having dermatomycosis was analysed in the mycological laboratory of the department of dermatology, charles university, prague. the most frequently examined locations were toenails (34.9%), feet (15.6%), fingernails (12.8%), toe webs (11%), trunk (10%) and hands (8.7%). dermatophytes were isolated from 5605 (30.2%) of all 18528 samples examined. amo ...200111820263
antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin.the phytoalexin resveratrol is commonly found in food and drinks, including red wine, grapes, and peanuts. many studies have shown that this compound has anti-inflammatory properties, and it has been ascribed as having health benefits that help to prevent cancer and coronary heart disease. a treatment that combines antimicrobial and anti-inflammatory actions may be desirable for alleviating many skin conditions that range in severity. therefore, we evaluated the antimicrobial activity of resvera ...200211841782
antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin.the phytoalexin resveratrol is commonly found in food and drinks, including red wine, grapes, and peanuts. many studies have shown that this compound has anti-inflammatory properties, and it has been ascribed as having health benefits that help to prevent cancer and coronary heart disease. a treatment that combines antimicrobial and anti-inflammatory actions may be desirable for alleviating many skin conditions that range in severity. therefore, we evaluated the antimicrobial activity of resvera ...200211841782
[dermatophyte flora at the dermatology clinic of kimitsu chuo hospital from 1994 through 1999].kimitsu chuo hospital is located in the middle of chiba prefecture along tokyo bay. an epidemiological survey of dermatophytosis was made at the dermatology clinic of the hospital from january 1994 through december 1999. dermatophytosis patients numbered 2,580 and disease types were composed of: tinea pedis 1,656 (64.2%), tinea unguium 377 (14.6%), tinea corporis 308 (11.9%), tinea cruris 139 (5.4%), tinea manuum 92 (3.6%), tinea capitis 6 (0.2%) and tinea profunda 2 (0.1%). species frequencies ...200211865297
[dermatophyte flora at the dermatology clinic of kimitsu chuo hospital from 1994 through 1999].kimitsu chuo hospital is located in the middle of chiba prefecture along tokyo bay. an epidemiological survey of dermatophytosis was made at the dermatology clinic of the hospital from january 1994 through december 1999. dermatophytosis patients numbered 2,580 and disease types were composed of: tinea pedis 1,656 (64.2%), tinea unguium 377 (14.6%), tinea corporis 308 (11.9%), tinea cruris 139 (5.4%), tinea manuum 92 (3.6%), tinea capitis 6 (0.2%) and tinea profunda 2 (0.1%). species frequencies ...200211865297
subcutaneous infection by microsporum gypseum.we report a case of subcutaneous infection caused by the dermatophyte microsporum gypseum in an immunocompetent host. the patient acquired the infection in the knee through a traumatic inoculation of a splinter. to our knowledge this is the first case of subcutaneous infection caused by this fungus.200211903246
subcutaneous infection by microsporum gypseum.we report a case of subcutaneous infection caused by the dermatophyte microsporum gypseum in an immunocompetent host. the patient acquired the infection in the knee through a traumatic inoculation of a splinter. to our knowledge this is the first case of subcutaneous infection caused by this fungus.200211903246
fungi isolated from skins and pens of healthy animals in nigeria.the mycoflora of 220 skin scrapings, hair, nail samples and pens' materials of apparently healthy animals including cows, sheep, goats, rabbits, pigs and dogs were determined. twenty eight species of fungi belonging to ten genera were recovered. chrysosporium spp. were the most common and c. keratinophilum was recovered from all animals. dermatophytes which are known causal agents of dermatophytosis were also isolated in different frequencies (microsporum gypseum, m. canis, trichophyton mentagro ...200211913761
fungi isolated from skins and pens of healthy animals in nigeria.the mycoflora of 220 skin scrapings, hair, nail samples and pens' materials of apparently healthy animals including cows, sheep, goats, rabbits, pigs and dogs were determined. twenty eight species of fungi belonging to ten genera were recovered. chrysosporium spp. were the most common and c. keratinophilum was recovered from all animals. dermatophytes which are known causal agents of dermatophytosis were also isolated in different frequencies (microsporum gypseum, m. canis, trichophyton mentagro ...200211913761
[fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh inula viscosa (asteraceae) flowers from the puglia region].a sesquiterpene lactone, tomentosin, has been isolated and identified form inula viscosá ait (asteraceae) flowers. the molecule, at 1 mg/ml concentration, showed to be active in vitro against microsporum canis, microsporum gypseum and trichophyton mentagrophytes.200111921538
[fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh inula viscosa (asteraceae) flowers from the puglia region].a sesquiterpene lactone, tomentosin, has been isolated and identified form inula viscosá ait (asteraceae) flowers. the molecule, at 1 mg/ml concentration, showed to be active in vitro against microsporum canis, microsporum gypseum and trichophyton mentagrophytes.200111921538
a chemically modified tetracycline (cmt-3) is a new antifungal agent.several chemically modified tetracycline analogs (cmts), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. of 10 cmts screened in vitro, all exhibited antifungal activities, although their efficacies varied. among these compounds, cmt-315, -3, and -308 were found to be the most potent as antifungal agents. the mics of cmt-3 against 47 strains of fungi in vitro were determined by using amphotericin b (amb) and doxycycl ...200211959581
a chemically modified tetracycline (cmt-3) is a new antifungal agent.several chemically modified tetracycline analogs (cmts), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. of 10 cmts screened in vitro, all exhibited antifungal activities, although their efficacies varied. among these compounds, cmt-315, -3, and -308 were found to be the most potent as antifungal agents. the mics of cmt-3 against 47 strains of fungi in vitro were determined by using amphotericin b (amb) and doxycycl ...200211959581
occurrence of keratinophilic fungi and dermatophytes on domestic birds in nigeria.feathers, nails and beaks of one hundred and twenty common birds in nigeria, chicken [50], ducks [20], turkeys [15] and pigeons [35], were examined using the soil plate technique for their mycoflora. 15 species of fungi were recovered and they belong to the genera chrysosporium, trichophyton, microsporum, aspergillus, fusarium, mucor rhizopus, penicillium and trichoderma. microsporum gypseum was the species most frequently isolated (35% of the samples). the most common genus was chrysosporium an ...200212000131
occurrence of keratinophilic fungi and dermatophytes on domestic birds in nigeria.feathers, nails and beaks of one hundred and twenty common birds in nigeria, chicken [50], ducks [20], turkeys [15] and pigeons [35], were examined using the soil plate technique for their mycoflora. 15 species of fungi were recovered and they belong to the genera chrysosporium, trichophyton, microsporum, aspergillus, fusarium, mucor rhizopus, penicillium and trichoderma. microsporum gypseum was the species most frequently isolated (35% of the samples). the most common genus was chrysosporium an ...200212000131
in vitro susceptibility of microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin.we investigated the in vitro activity of terbinafine against fresh veterinary isolates of microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy. dermatophyte cultures (n = 300) were obtained from naturally infected cats and dogs undergoing oral therapy with terbinafine or griseofulvin. m. canis comprised 92% of isolates; other species included microsporum gypseum and trichophyton mentagrophytes. minimum inhibitory concentrations (mics) and minimum ...200212058731
in vitro susceptibility of microsporum canis and other dermatophyte isolates from veterinary infections during therapy with terbinafine or griseofulvin.we investigated the in vitro activity of terbinafine against fresh veterinary isolates of microsporum canis and the potential of this organism to develop resistance in vivo during oral therapy. dermatophyte cultures (n = 300) were obtained from naturally infected cats and dogs undergoing oral therapy with terbinafine or griseofulvin. m. canis comprised 92% of isolates; other species included microsporum gypseum and trichophyton mentagrophytes. minimum inhibitory concentrations (mics) and minimum ...200212058731
use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes.the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ...200212089289
use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes.the sensititre yeastone antifungal panel was used to test 49 dermatophytes belonging to the species epidermophyton floccosum, microsporum gypseum, microsporum canis, trichophyton tonsurans, trichophyton rubrum, and trichophyton mentagrophytes. the mics of four antifungals obtained with the sensititre yeastone antifungal panel were compared with those obtained by the reference nccls microdilution method. the levels of agreement between the two methods (<or=2 dilutions) were 81.6% with amphoterici ...200212089289
copper complexes with bioactive ligands. part ii--antifungal activity.antifungal activity of new copper(ii) complexes of 2-methylthionicotinate (2-mesnic) of the composition cu(2-mesnic)2(menia)(2).4h2o (where menia is n-methylnicotinamide), and cu(2-mesnic)2(nia)(2).2h2o (where nia is nicotinamide) and cu(2-mesnic)2l2 (where l is isonicotinamide, inia, or ethyl nicotinate, etnic) were tested on various strains of filamentous fungi by the macrodilution method. most sensitive against copper(ii) adducts with bioactive ligands were rhizopus oryzae and microsporum gyp ...200212094729
copper complexes with bioactive ligands. part ii--antifungal activity.antifungal activity of new copper(ii) complexes of 2-methylthionicotinate (2-mesnic) of the composition cu(2-mesnic)2(menia)(2).4h2o (where menia is n-methylnicotinamide), and cu(2-mesnic)2(nia)(2).2h2o (where nia is nicotinamide) and cu(2-mesnic)2l2 (where l is isonicotinamide, inia, or ethyl nicotinate, etnic) were tested on various strains of filamentous fungi by the macrodilution method. most sensitive against copper(ii) adducts with bioactive ligands were rhizopus oryzae and microsporum gyp ...200212094729
tinea capitis due to microsporum gypseum. 200212095884
tinea capitis due to microsporum gypseum. 200212095884
report of two cases of tinea infection with scutula-like lesions caused by microsporum gypseum. 200212100698
report of two cases of tinea infection with scutula-like lesions caused by microsporum gypseum. 200212100698
degradation of keratin substrates by fungi isolated from sewage sludge.four fungal species including two dermatophytes and two saprophytes were isolated from sewage sludge samples at basrah (iraq) they were tested for their degradative ability towards three types of keratin substrates (human hair, chicken feathers and wool). the rate of keratin degradation was expressed as weight loss over three weeks of incubation using a liquid culture medium. human hair had the highest degradation rate by colonization of chrysosporium pannicola and microsporum gypseum at a rate ...200212206319
degradation of keratin substrates by fungi isolated from sewage sludge.four fungal species including two dermatophytes and two saprophytes were isolated from sewage sludge samples at basrah (iraq) they were tested for their degradative ability towards three types of keratin substrates (human hair, chicken feathers and wool). the rate of keratin degradation was expressed as weight loss over three weeks of incubation using a liquid culture medium. human hair had the highest degradation rate by colonization of chrysosporium pannicola and microsporum gypseum at a rate ...200212206319
stereoselective synthesis and in vitro antifungal evaluation of (e)- and (z)-imidazolylchromanone oxime ethers.a series of (e)- and (z)-2, 3-dihydro-3-(1h-imidazol-1-yl)-4h-1-benzopyran-4-one oxime ethers have been synthesized and tested for antifungal activity. most compounds showed moderate to potent in vitro antifungal activity. among the tested compounds, compound (e)-3d was the most active agent against candida albicans and aspergillus niger, and compounds (z)-(3a) and (e)-3a were the most potent compounds against microsporum gypseum. detailed stereoselective synthesis, spectroscopic, and biological ...200212207281
stereoselective synthesis and in vitro antifungal evaluation of (e)- and (z)-imidazolylchromanone oxime ethers.a series of (e)- and (z)-2, 3-dihydro-3-(1h-imidazol-1-yl)-4h-1-benzopyran-4-one oxime ethers have been synthesized and tested for antifungal activity. most compounds showed moderate to potent in vitro antifungal activity. among the tested compounds, compound (e)-3d was the most active agent against candida albicans and aspergillus niger, and compounds (z)-(3a) and (e)-3a were the most potent compounds against microsporum gypseum. detailed stereoselective synthesis, spectroscopic, and biological ...200212207281
antimicrobial and anti-inflammatory activity of folklore: mallotus peltatus leaf extract.since ages mallotus peltatus (geist) muell. arg. var acuminatus (euphorbiaceae) leaf and stem bark is used in folk medicine to cure intestinal ailments and skin infections. in several intestinal ailments, localized inflammation is of common occurrence and hence we have evaluated the antimicrobial as well as anti-inflammatory activity of m. peltatus leaf extract. the crude methanol extract of m. peltatus leaves was found to be active against staphylococcus aureus, staphylococcus saprophyticus, st ...200212242000
antimicrobial and anti-inflammatory activity of folklore: mallotus peltatus leaf extract.since ages mallotus peltatus (geist) muell. arg. var acuminatus (euphorbiaceae) leaf and stem bark is used in folk medicine to cure intestinal ailments and skin infections. in several intestinal ailments, localized inflammation is of common occurrence and hence we have evaluated the antimicrobial as well as anti-inflammatory activity of m. peltatus leaf extract. the crude methanol extract of m. peltatus leaves was found to be active against staphylococcus aureus, staphylococcus saprophyticus, st ...200212242000
chemical analysis and antifungal activity of the essential oil of calea clematidea.the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ...200212357399
chemical analysis and antifungal activity of the essential oil of calea clematidea.the chemical composition of the essential oils of calea clematidea baker obtained by hydrodistillation of the leaves and flowers was analysed by gc and gc/ms and the oils were assayed for their antifungal activities. the essential oil of the leaves showed a high content of a new natural epoxy terpenoid, named clemateol (ca. 70 %), with minor amounts of o-vanillin (6.5 %), spathulenol (4.2 %), alpha-terpinene (4.0 %), germacrene b (2.9 %), yomogi alcohol (1.8 %), ( e)-caryophylene (1.7 %), m-cyme ...200212357399
can zinc be used for the treatment of microsporum gypseum dermatitis in man as well as in sheep? 200212385705
can zinc be used for the treatment of microsporum gypseum dermatitis in man as well as in sheep? 200212385705
did earthworms contribute to the parasitic evolution of dermatophytes?the survival of dermatophyte species in the gut of four species of earthworms was studied by feeding the fungi to the earthworms. recovery of the dermatophyte species in culture from the guts was only possible for microsporum gypseum and chrysosporium keratinophilum. in the light of these findings, we presume that earthworms could have influenced the parasitic evolution of certain dermatophytes.200212421289
did earthworms contribute to the parasitic evolution of dermatophytes?the survival of dermatophyte species in the gut of four species of earthworms was studied by feeding the fungi to the earthworms. recovery of the dermatophyte species in culture from the guts was only possible for microsporum gypseum and chrysosporium keratinophilum. in the light of these findings, we presume that earthworms could have influenced the parasitic evolution of certain dermatophytes.200212421289
fungal flora of human toe webs.a total of 100 young adults (67 males and 33 females) participated in the study. clinical evaluation showed that only 10 of the volunteers showed some scaling, fissuring and peeling of the toe webs. four of these complained of occasional itching. fourteen different genera of fungi were recovered from 78 of the 100 youths screened. yeasts were recovered from 21 (27%) of the positive cases, nondermatophytes from 38 (49%) and dermatophytes from 19 (24%). microsporum gypseum was the most commonly re ...200212472726
fungal flora of human toe webs.a total of 100 young adults (67 males and 33 females) participated in the study. clinical evaluation showed that only 10 of the volunteers showed some scaling, fissuring and peeling of the toe webs. four of these complained of occasional itching. fourteen different genera of fungi were recovered from 78 of the 100 youths screened. yeasts were recovered from 21 (27%) of the positive cases, nondermatophytes from 38 (49%) and dermatophytes from 19 (24%). microsporum gypseum was the most commonly re ...200212472726
in vitro antifungal activity of 3-phenyl-2h-benzoxazine-2,4(3h)-diones.a series of 81 3-phenyl-2h-benzoxazine-2,4(3h)-diones with substitution at c(6) on the benzoxazine ring and on the phenyl moiety was synthesized; the compounds were evaluated for antifungal activity against five strains of potentially pathogenic fungi (absidia corymbifera, aspergillus fumigatus, candida albicans, microsporum gypseum and trichophyton mentagrophytes). structure-activity relationships against t. mentagrophytes and m. gypseum were determined using the free-wilson method, which was f ...200212503392
in vitro antifungal activity of 3-phenyl-2h-benzoxazine-2,4(3h)-diones.a series of 81 3-phenyl-2h-benzoxazine-2,4(3h)-diones with substitution at c(6) on the benzoxazine ring and on the phenyl moiety was synthesized; the compounds were evaluated for antifungal activity against five strains of potentially pathogenic fungi (absidia corymbifera, aspergillus fumigatus, candida albicans, microsporum gypseum and trichophyton mentagrophytes). structure-activity relationships against t. mentagrophytes and m. gypseum were determined using the free-wilson method, which was f ...200212503392
the fungicidal activity of novel nanoemulsion (x8w60pc) against clinically important yeast and filamentous fungi.surfactant nanoemulsions are water in oil preparations that proved to have a broad spectrum biocidal activity against a variety of microorganisms including gram-positive and gram-negative bacteria, spores and enveloped viruses. these preparations are non-toxic to the skin, mucous membrane and gastrointestinal tissues at biocidal concentrations. in this study, 0.1% of the nanoemulsion designated x8w60pc has shown fungicidal activity against yeast including candida albicans and c. tropicalis in 15 ...200212650595
the fungicidal activity of novel nanoemulsion (x8w60pc) against clinically important yeast and filamentous fungi.surfactant nanoemulsions are water in oil preparations that proved to have a broad spectrum biocidal activity against a variety of microorganisms including gram-positive and gram-negative bacteria, spores and enveloped viruses. these preparations are non-toxic to the skin, mucous membrane and gastrointestinal tissues at biocidal concentrations. in this study, 0.1% of the nanoemulsion designated x8w60pc has shown fungicidal activity against yeast including candida albicans and c. tropicalis in 15 ...200212650595
a study of dermatophytes and their in-vitro antifungal sensitivity.of the 150 clinically suspected cases of dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), tinea corporis (48.7%) and tinea capitis (18%) were the commonest clinical types. the isolation rate was 24% (36) of which 19 (52.7%) were trichophyton rubrum, 11 (30.55%) were trichophyton mentagrophytes and 4 (11.1%) were trichophyton violaceum. one isolate each of microsporum gypseum & epidermophyton floccosum were obtained. griseofulvin proved to be the best dr ...200212696733
a study of dermatophytes and their in-vitro antifungal sensitivity.of the 150 clinically suspected cases of dermatophytosis studied, majority of the cases were from age group 11-20 and 21-30 (51.4%), tinea corporis (48.7%) and tinea capitis (18%) were the commonest clinical types. the isolation rate was 24% (36) of which 19 (52.7%) were trichophyton rubrum, 11 (30.55%) were trichophyton mentagrophytes and 4 (11.1%) were trichophyton violaceum. one isolate each of microsporum gypseum & epidermophyton floccosum were obtained. griseofulvin proved to be the best dr ...200212696733
dermatophytes isolated from symptomatic dogs and cats in tuscany, italy during a 15-year-period.between january, 1, 1986 and december, 31, 2000, dermatological specimens from 10.678 animals (7.650 cats and 3.028 dogs) were examined for dermatophytes. all the animals presented clinical signs of ringworm. two thousand-four hundred fifty-six of the 10.678 (23%) examined animals scored positive for dermatophytes, 566 out of 3.028 canine (18.7%) and 1890 out of 7.650 feline specimens (24.7%). microsporum canis constituted 83% and 97% of the isolated dermatophytes respectively in dogs and cats, ...200212715942
dermatophytes isolated from symptomatic dogs and cats in tuscany, italy during a 15-year-period.between january, 1, 1986 and december, 31, 2000, dermatological specimens from 10.678 animals (7.650 cats and 3.028 dogs) were examined for dermatophytes. all the animals presented clinical signs of ringworm. two thousand-four hundred fifty-six of the 10.678 (23%) examined animals scored positive for dermatophytes, 566 out of 3.028 canine (18.7%) and 1890 out of 7.650 feline specimens (24.7%). microsporum canis constituted 83% and 97% of the isolated dermatophytes respectively in dogs and cats, ...200212715942
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