Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| genomic variations among bartonella henselae isolates derived from naturally infected cats. | the purpose of this study was to understand the mechanisms of persistent infection with bartonella henselae in cats. blood samples were collected from three naturally infected cats for 24 months. these cats were confirmed to be persistently infected with b. henselae by serological and bacteriological examination. relapsing bacteremia was found in all three cats with intervals of 3-19 months. following the peaks of bacteremia, increases of specific antibody titer were observed in these cats. to e ... | 2002 | 12243898 |
| improved culture from lymph nodes of patients with cat scratch disease and genotypic characterization of bartonella henselae isolates in australia. | over a 4-year period we detected bartonella henselae isolates in 104 of 297 specimens (35.1%) from australian patients clinically suspected of having cat scratch disease by amplification of a fragment of the htra gene. we isolated 17 b. henselae strains (20.5%) from the 83 pcr-positive human specimens available for culture. our culture method was based on prolonged incubation in a moist atmosphere of blood agar to which hemin was added. we obtained more b. henselae isolates than the number of al ... | 2002 | 12354855 |
| cases from the osler medical service at johns hopkins university. bartonella henselae infection of the liver and spleen. | 2002 | 12361825 | |
| [endocarditis due to bartonella henselae on a native valve. a new case with some notable aspects]. | 2002 | 12372243 | |
| co-infection with esptein-barr virus and bartonella henselae resulting in systemic bartonellosis. | 2002 | 12387781 | |
| joint and bone infections due to anaerobic bacteria in children. | the current review describes the microbiology, diagnosis and management of septic arthritis and osteomyelitis due to anaerobic bacteria in children. staphylococcus aureus, haemophilus influenzae type-b, and group a streptococcus, streptococcus pneumoniae, kingela kingae, neisseria meningiditis and salmonella spp are the predominant aerobic bacteria that cause arthritis in children. gonococcal arthritis can occur in sexually active adolescents. the predominant aerobes causing osteomyelitis in chi ... | 2002 | 12396847 |
| antigenic and genotypic relationships between bartonella henselae strains. | 2002 | 12409443 | |
| [vertebral osteomyelitis associated with cat scratch disease]. | 2002 | 12433360 | |
| activation and apoptosis of macrophages in cat scratch disease. | cat scratch disease is an infectious disease usually caused by bartonella henselae. within 1-3 weeks after inoculation, patients typically develop regional self-limited lymphadenopathy. lymph nodes reveal granulomas consisting of central necrosis, an inner rim of palisading macrophages, and an outer rim of lymphocytes and non-palisading macrophages. in animals, cat-scratch disease leads to an interferon-gamma (ifngamma)-mediated t-helper 1 immune response, resulting in macrophage recruitment, st ... | 2002 | 12434424 |
| prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown los angeles. | norway rats (rattus norvegicus) are hosts for various microbes. homeless people who have contact with rats may be at risk of infection by them. the los angeles county department of health services initiated a seroepidemiologic study among patients who used a free clinic in downtown los angeles; 200 serum specimens obtained for other routine assays were tested for antibodies to ratborne pathogens and other agents. the seroprevalence of antibody to hepatitis e virus in this population was 13.6%; t ... | 2002 | 12447746 |
| molecular epidemiology of bartonella henselae infection in human immunodeficiency virus-infected patients and their cat contacts, using pulsed-field gel electrophoresis and genotyping. | bartonella henselae causes severe disease in immunocompromised individuals. b. henselae was isolated from 12 human immunodeficiency virus (hiv)-infected individuals with bacillary angiomatosis and/or peliosis hepatis and from their 15 cat contacts. specific associations between the 2 b. henselae genotypes, individual pulsed-field gel electrophoresis (pfge) patterns, and different clinical syndromes and pathogenicity were investigated. the role of cat contacts as the source of human infection was ... | 2002 | 12447758 |
| bartonella henselae and bartonella elizabethae as potential canine pathogens. | bartonella henselae or bartonella elizabethae dna from edta-anticoagulated blood samples obtained from four dogs was amplified and sequenced. the results showed that b. elizabethae should be added to the list of bartonella species (i.e., b. vinsonii subsp. berkhoffii, b. henselae, and b. clarridgeiae) that are currently recognized as infectious agents in dogs. furthermore, these results may have potential zoonotic implications, particularly if dogs can serve as a previously unrecognized reservoi ... | 2002 | 12454170 |
| limited diversity among human isolates of bartonella henselae. | a study of 59 isolates of bartonella henselae reveals relatively limited diversity among those of human origin (n = 28). either of two distinct alleles of both glta and 16s ribosomal dna (rdna) was found in all isolates, with a high level of congruity between 16s and glta inheritance among proven human pathogens. human isolates from all over eastern australia were most commonly 16s rdna (bergmans) type i, with the same glta allele as the type strain (houston-1). comparable feline isolates were m ... | 2002 | 12454174 |
| rickettsial, ehrlichial and bartonella infections of the myocardium and pericardium. | myocarditis and pericarditis are uncommon complications of human rickettsial, ehrlichial and bartonella infections. myocardial inflammation usually occurs in the setting of acute disseminated infection. organisms associated with myocarditis include: rickettsia rickettsii, r. conorii, orientia tsutsugamushi, coxiella burnetii, anaplasma phagocytophila (the causative agent of human granulocytic ehrlichiosis) and bartonella henselae. pericarditis has been described in the setting of r. conorii and ... | 2003 | 12456377 |
| vertebral osteomyelitis in 2 children. | 2002 | 12462322 | |
| vertebral osteomyelitis due to bartonella henselae in adults: a report of 2 cases. | we describe 2 adult patients (1 of whom was infected with human immunodeficiency virus) with osteomyelitis due to bartonella henselae. diagnosis was established on the basis of direct identification of the microorganism in one case and seroconversion in the other. both patients recovered completely within 3 months. | 2002 | 12471592 |
| high rate of bartonella henselae infection in hiv-positive outpatients in johannesburg, south africa. | the emerging opportunistic pathogen bartonella henselae has a wide range of clinical presentation, which includes, particularly, bacillary angiomatosis. this non-random pilot survey of outpatients attending hiv clinics in johannesburg, south africa, sampled 188 patients, in whom there was a 10% prevalence of bartonella bacteraemia, as determined by nested polymerase chain reaction. | 2002 | 12474487 |
| infection and re-infection of domestic cats with various bartonella species or types: b. henselae type i is protective against heterologous challenge with b. henselae type ii. | four bartonella species have been isolated from domestic cats, of which two serotypes/genotypes of bartonella henselae and possibly b. clarridgeiae are human pathogens, causing cat scratch disease (csd).our objectives were to evaluate infection and potential cross-protection during re-infection in domestic cats with various bartonella species or types.thirty-six cats were primarily inoculated with b. henselae type i (n=16), b. henselae type ii (n=10), b. clarridgeiae (n=6) or b. koehlerae (n=4). ... | 2003 | 12488072 |
| isolated splenic cat scratch disease in an immunocompetent adult woman. | we report a case of isolated splenic cat scratch disease in an immunocompetent woman. the clinical presentation of prolonged fever, night sweats, weakness, and intrasplenic lesions was highly suggestive of lymphoma. this is the second reported case of isolated splenic cat scratch disease in an adult and the first in a healthy adult. | 2003 | 12491224 |
| studies on the growth of bartonella henselae in the cat flea (siphonaptera: pulicidae). | two out of three pools of cat fleas, ctenocephalides felis (bouche), that were fed bartonella henselae-positive cat blood for 3 d and then bovine blood for 3 d, were polymerase chain reaction (pcr) positive for b. henselae. in a second experiment, three cats were inoculated with a streptomycin-resistant strain of b. henselae. after the cats were inoculated, caged cat fleas were fed on the cats during three different periods, and then pooled and transferred to noninfected recipient cats. in the f ... | 2002 | 12495192 |
| experimental infection of specific pathogen free (spf) cats with two different strains of bartonella henselae type i: a comparative study. | domestic cats are the reservoir of bartonella henselae, the main causative agent of cat scratch disease. we compared b. henselae type i infection characteristics in 6 spf cats infected with a feline strain (4.8 x 10(7) colony-forming units (cfu)/ml) and in 6 spf cats infected with the reference houston i strain (6.6 x 10(6) cfu/ml to 9.6 x 10(7) /ml). all the cats inoculated with the feline strain, but none of the cats inoculated with b. henselae houston i, developed a fever within 2-12 days (me ... | 2002 | 12498568 |
| clinical microbiological case: severe relapsing septal panniculitis in a healthy man from the south-eastern usa. | 2002 | 12519353 | |
| detection of bartonella henselae and bartonella clarridgeiae dna in hepatic specimens from two dogs with hepatic disease. | a 4-year-old basset hound and a 6-year-old doberman pinscher were referred for diagnostic evaluation following documentation of persistently increased hepatic enzyme activities and hepatic dysfunction. histologic evaluation of hepatic biopsy specimens from the 2 dogs revealed granulomatous hepatitis in the basset hound and lymphocytic hepatitis with fibrosis and copper accumulation in the doberman pinscher. no etiologic agents were identified histologically. bartonella henselae dna was subsequen ... | 2003 | 12523479 |
| cat scratch disease in japan. | 2002 | 12525891 | |
| a prospective study of cat-scratch disease in lima-peru. | cat-scratch disease (csd) is a benign lymphadenitis that may progress to severe or recurrent forms, and it is occasionally associated with morbidity. between january of 1998 and march of 1999, forty-three suspected csd patients were assessed in the hospital cayetano heredia and the instituto de salud del niño, in lima, peru. twelve patients had a confirmed diagnosis, 8 of whom were women, and the mean age was 10 years old. the majority (53%) of the cases were encountered in the summer. all patie ... | 2002 | 12532216 |
| [three cases of bartonellosis (cat scratch disease)]. | in the last years the number of bartonella species has conspicuously increased, with better clinical and diagnostic definitions of the different related illnesses. we report, in the present article, 3 cases of cat-scratch disease, a particular bartonellosis mainly caused by bartonella henselae which is transmitted by the cat. after an incubation period, cat-scratch disease clinically manifests as a regional lymphoadenitis, with the appearance of a small cutaneous lesion at the site of inoculatio ... | 2002 | 12532565 |
| bartonella henselae infective endocarditis in north queensland. | 2003 | 12534881 | |
| five-member gene family of bartonella quintana. | bartonella quintana, the agent of trench fever and an etiologic agent of bacillary angiomatosis, has an extraordinarily high hemin requirement for growth compared to other bacterial pathogens. we previously identified the major hemin receptor of the pathogen as a 30-kda surface protein, termed hbpa. this report describes four additional homologues that share approximately 48% amino acid sequence identity with hbpa. three of the genes form a paralagous cluster, termed hbpcab, whereas the other me ... | 2003 | 12540561 |
| aids presenting with cutaneous kaposi's sarcoma and bacillary angiomatosis in the bone marrow mimicking kaposi's sarcoma. | kaposi's sarcoma (ks) and bacillary angiomatosis (ba) may be histologically similar. a precise diagnosis is required because of the different management of these diseases. ks or ba involving bone marrow is rare in patients with and without acquired immune deficiency syndrome (aids). we report the case of a 40-year-old human immunodeficiency virus (hiv)-positive homosexual male who presented with small ks lesions in the skin and ba in the bone marrow that histologically were similar. laboratory e ... | 2002 | 12542930 |
| mass lesions of the posterior segment associated with bartonella henselae. | 2003 | 12543767 | |
| cat-scratch disease presenting as a solitary tumour in the breast: report of three cases. | cat-scratch disease (csd) may appear as a solitary mass in the breast and give the impression of a breast carcinoma. in this case, further clinical and laboratory investigation is required to rule out malignancy. we present three cases of csd of the breast in women of 64, 31 and 61 years old. each presented with enlarged lymph-nodes in the breast, which were clinically mistaken for solitary tumours. in the first two patients, the mammography was negative. the third patient had a mammogram which ... | 2003 | 12551788 |
| cat scratch disease (csd) in patients with stellate neuroretinitis: 3 cases. | this case series describes three patients with a similar clinical picture: unilateral abrupt visual loss, optic nerve edema, and a macular star exudate. in all cases we found significant antibody titers to bartonella henselae, the causative agent of cat scratch disease. cat scratch disease seems to be the most common cause of stellate neuroretinitis, formerly known as leber's idiopathic stellate retinopathy. a review of the pertinent literature shows that serologic evidence of b. henselae is suf ... | 2002 | 12564316 |
| comparison of pcr assays for detection of the agent of human granulocytic ehrlichiosis, anaplasma phagocytophilum. | human granulocytic ehrlichiosis is an emerging infectious disease in the united states and europe, and pcr methods have been shown to be effective for the diagnosis of acute infections. numerous pcr assays and primer sets have been reported in the literature. the analytical sensitivities (limits of detection) of 13 published pcr primer sets were compared using dna extracted from serial dilutions of anaplasma phagocytophilum-infected hl-60 cells. the specificity of the assays that were able to de ... | 2003 | 12574272 |
| molecular diagnosis of infective endocarditis by pcr amplification and direct sequencing of dna from valve tissue. | we used broad-range eubacterial pcr amplification followed by direct sequencing to identify microbial pathogens in heart valve material from 29 patients with histologically confirmed infective endocarditis and 23 patients free of infective endocarditis. microorganisms cultured by conventional techniques matched those identified by pcr in 21 cases. pcr alone identified the causative agent in three cases (streptococcus bovis, staphylococcus cohnii, and coxiella burnetii), allowing better patient m ... | 2003 | 12574279 |
| [cat scratch disease--diagnostic problems]. | etiology, epidemiology and clinical symptoms of mollaret's disease, also known as cat-scratch disease, were described. four cases of treated patients were presented. one patient with a history of type i diabetes mellitus presented clinical symptoms of mollaret's disease, however, after investigation he was finally diagnosed with malignant lymphoma and was given chemotherapy. in other cases some symptoms were also doubtful, but the final diagnoses were made upon positive results of serological re ... | 2002 | 12577490 |
| characterization of the cryptic plasmid pbgr1 from bartonella grahamii and construction of a versatile escherichia coli-bartonella spp. shuttle cloning vector. | we report herein the isolation and molecular characterization of pbgr1, the first native plasmid isolated from the genus bartonella. cloning and sequencing revealed a 2725-base pair (bp) cryptic plasmid comprising two open reading frames of considerable length, which were designated rep and mob. the regions containing rep and mob are separated by 140-bp inverted repeat sequences and display a difference in g + c content from one another. a 1435-bp saci-bcli fragment containing the rep gene is su ... | 2003 | 12584000 |
| hemin binding, functional expression, and complementation analysis of pap 31 from bartonella henselae. | growth of bartonella henselae is strongly heme dependent, and b. henselae is unable to synthesize heme itself. at least five outer membrane-associated proteins from b. henselae bind hemin, including the 31-kda protein designated pap31. the gene of this protein was heterologously expressed in escherichia coli m15(prep4) and detected with monoclonal antibodies in the outer membrane fraction. complementation of the hema-deficient mutant e. coli k-12 eb53 (arob tsx malt hema) with pap31 demonstrated ... | 2003 | 12591895 |
| clinical quiz: cat scratch disease. | 2003 | 12593397 | |
| unusual presentation of cat scratch disease in hiv+ patient. | 2003 | 12598467 | |
| [seroprevalence of bartonella henselae and bartonella quintana infections in poland in 1998-2001]. | bartonella henselae and bartonella quintana infections result in illnesses with symptoms of severity ranging from mild lymphadenopathy (csd) to systemic disease. the aim of the study was to estimate a prevalence of b. henselae and b. quintana infections in human in poland. serum samples collected from 265 patients in 1998-2001 were tested for the presence of antibodies specific to b. henselae and b. quintana. levels of serum igm and igg antibodies to bartonella henselae and bartonella quintana w ... | 2002 | 12608089 |
| type iv transporters of pathogenic bacteria. | type iv transporters are produced by several bacterial pathogens such as agrobacterium tumefaciens, bordetella pertussis, brucella spp., bartonella henselae, helicobacter pylori and legionella pneumophila. these transporters are critical for the pathogenic process in that they export important virulence factors across the membranes of the bacteria. although the virulence factors that are exported by these transporters can be either nucleic acid or protein, the general mechanism of transport appe ... | 2003 | 12615216 |
| recent progress in understanding bartonella-induced vascular proliferation. | the ability to induce endothelial cell proliferation is a common feature of human pathogenic bartonella species. recent data have indicated that bartonellae can provoke angioproliferation by at least two independent mechanisms: directly, by triggering proliferation and inhibiting apoptosis of endothelial cells; and indirectly, by stimulating a paracrine angiogenic loop of vascular endothelial growth factor production by infected macrophages. a nf-kappab-mediated acute inflammatory reaction of th ... | 2003 | 12615221 |
| a rhizobium leguminosarum acpxl mutant produces lipopolysaccharide lacking 27-hydroxyoctacosanoic acid. | the structure of the lipid a from rhizobium etli and rhizobium leguminosarum lipopolysaccharides (lpss) lacks phosphate and contains a galacturonosyl residue at its 4' position, an acylated 2-aminogluconate in place of the proximal glucosamine, and a very long chain omega-1 hydroxy fatty acid, 27-hydroxyoctacosanoic acid (27ohc28:0). the 27ohc28:0 moiety is common in lipid a's among members of the rhizobiaceae and also among a number of the facultative intracellular pathogens that form chronic i ... | 2003 | 12618448 |
| [three toddlers with a swelling in the neck]. | three children, a girl aged 2.5 years and two boys aged 2 and 3 years respectively, presented with unilateral cervical lymphadenitis. the first patient had acute bacterial lymphadenitis due to group a streptococcus, characterised by a painful cervical swelling of acute onset. the second patient had painless cervical lymphadenitis caused by mycobacterium avium-intracellulare, which drained spontaneously. the third patient developed a non-tender, cervical swelling within a day. he too was systemic ... | 2003 | 12621974 |
| phase variation in bartonella henselae. | bartonella henselae is a fastidious, gram-negative bacterial pathogen of cats and humans. previous workers have shown that serial passage in vitro leads to attenuation of virulence-associated attributes such as expression of pili, invasion of human epithelial cell lines and the stimulation of endothelial cell proliferation. in contrast to the published data, it was found that pilin expression is frequently preserved in organisms which have undergone phase variation in vitro. transition from a sl ... | 2003 | 12634331 |
| oral corticosteroids in cat-scratch disease. | 2003 | 12635985 | |
| detection of bartonella henselae dna using polymerase chain reaction assay in patient with cat scratch disease. | 2003 | 12636034 | |
| bartonella henselae in ixodes ricinus ticks (acari: ixodida) removed from humans, belluno province, italy. | the potential role of ticks as vectors of bartonella species has recently been suggested. in this study, we investigated the presence of bartonella species in 271 ticks removed from humans in belluno province, italy. by using primers derived from the 60-kda heat shock protein gene sequences, bartonella dna was amplified and sequenced from four ixodes ricinus ticks (1.48%). to confirm this finding, we performed amplification and partial sequencing of the pap31 protein and the cell division protei ... | 2003 | 12643827 |
| [cat scratch disease with posterior segment involvement]. | to describe the clinical characteristics of patients with cat scratch disease during the last 2 years. | 2003 | 12647335 |
| urban zoonoses caused by bartonella, coxiella, ehrlichia, and rickettsia species. | the last half of the 20th century witnessed an increase in the occurrence and recognition of urban zoonoses caused by members of the genera bartonella, coxiella, ehrlichia, and rickettsia, all traditionally considered to be members of the family rickettsiaceae. in recent years, new human pathogens (bartonella elizabethae, bartonella henselae, and rickettsia felis) have been recognized in urban environments. other newly recognized pathogens (ehrlichia chaffeensis and ehrlichia phagocytophila in t ... | 2001 | 12653141 |
| [hepatosplenic localization of cat scratch disease in immunocompetent adults. two cases]. | the infective agent responsible for cat scratch disease, bartonella henselae, is a rare cause of hepatic granulomatosis in immunocompetent adults. clinical features include a prolonged fever or more typical symptoms such as lymphadenopathy associated with painful hepatomegaly and a fever following a cat scratch or bite. images of micronodular hepatosplenic lesions on abdominal ultrasonography or computed tomography scan along with epithelioid granulomas in a liver biopsy can suggest this diagnos ... | 2003 | 12658133 |
| cure of bartonella endocarditis of a prosthetic aortic valve without surgery: value of serologic follow-up. | bartonella species are emerging as an important cause of blood culture-negative endocarditis, but the optimal management of this disease has not been fully defined. we describe a case of subacute bartonella henselae endocarditis of a prosthetic aortic valve in an immunocompetent woman that was cured with long-term antibiotic therapy alone. in addition, we demonstrate that follow-up of serologic titers against b. henselae was helpful in assessing definitive cure of the infection. | 2003 | 12667258 |
| primary lesion of cat-scratch disease and inguinal cat-scratch disease. | 2003 | 12674683 | |
| prevalence of bartonella henselae in young, healthy cats in sweden. | 2003 | 12678262 | |
| seroprevalence of bartonella henselae, toxoplasma gondii, fiv and felv infections in domestic cats in japan. | seroprevalence of bartonella henselae, toxoplasma gondii, feline immunodeficiency virus (fiv) and feline leukemia virus (felv) infections was investigated in 1,447 domestic cats derived from the north (hokkaido) to the south (okinawa) prefectures in japan. of the cats investigated, 8.8% (128/1,447) were seropositive to b. henselae, 5.4% (78/1,447) to t. gondii, 9.8% (107/1,088) to fiv, and 2.9% (32/1,088) to felv, respectively. for b. henselae infection, the positive rate varied from 11.5% in ca ... | 2003 | 12680718 |
| [transverse myelitis associated with cat-scratch disease]. | 2003 | 12681227 | |
| characterization of the human autoimmune response to the major c-terminal epitope of the ribosomal p proteins. | autoantibodies to the ribosomal phospho (-p) proteins p0, p1, and p2, collectively referred to as rib-p, are specifically found in 10-40% of patients with systemic lupus erythematosus (sle). these antibodies are believed to be correlated with lupus nephritis, hepatitis, and central nervous system involvement. the major immunoreactive epitope of these ribosomal antigens has been localized to the carboxy terminus, which is a highly conserved domain of all three proteins and contains two phosphoryl ... | 2003 | 12682728 |
| urban trench fever and cat scratch disease. | 2003 | 12684929 | |
| bartonella henselae: association with the development of transient lupus anticoagulant and asymptomatic prolongation of activated partial thromboplastin time. | 2003 | 12693573 | |
| detection and characterization of feline bartonella henselae in the czech republic. | the aims of the study were to characterize isolates of bartonella henselae and to determine the prevalence of bacteremic domestic cats in urban and suburban parts of prague, czech republic. five (18%) gram-negative fastidious bacterial single-cat isolates were recovered from 27 hemocultures incubated without previous freezing. four of these isolates originated from flea infested stray cats (n=6) and one from a shelter cat without any ectoparasites (n=21). none of the 34 previously frozen specime ... | 2003 | 12695049 |
| [possible bacterial etiologies for diseases of unknown origin]. | 2003 | 12717985 | |
| [cat scratch disease]. | 2003 | 12722263 | |
| immune responses of immunocompetent and immunocompromised mice experimentally infected with bartonella henselae. | the aim of this study is to understand host immune responses in immunocompetent and immunocompromised mice against bartonella henselae infection. balb/c and nude (balb/c nu/nu) mice were inoculated intraperitoneally with 10(8) colony forming units of b. henselae (houston-1 strain). blood, brain, liver, spleen, kidney and bone marrow samples were collected 0, 3, 7, 14, 21 and 28 days after infection and submitted to bacteriological, serological and genetical examinations. b. henselae was isolated ... | 2003 | 12736430 |
| chronic osteomyelitis associated with cat-scratch disease. | cat-scratch disease (csd) is usually a self-limited illness, though atypical presentations of infection with bartonella henselae can occur, including osteomyelitis, oculoglandular syndrome, and granulomatous hepatitis. we describe a 6-year-old boy who had atypical csd osteomyelitis of the left proximal femoral metaphysis due to a cat scratch. this is the second paper to report serial serology of b henselae, and the second paper to identify plasma cells on histologic examination, compatible with ... | 2002 | 12741593 |
| rapid polymerase chain reaction-based confirmation of cat scratch disease and bartonella henselae infection. | cat scratch disease (csd) commonly occurs secondary to bartonella henselae infection, and the diagnosis has traditionally been made by microscopic findings, the identification of organisms by cytochemistry, and clinical history. however, cytochemical analysis tends to be very difficult to interpret, and histology alone may be insufficient to establish a definitive diagnosis of csd. | 2003 | 12741894 |
| [severe retinal phlebitis in ocular bartonellosis]. | purpose/methods: to report the clinical case of a 34-year-old male with atypical ophthalmic manifestations of cat-scratch disease (ocular bartonellosis), including an extensive retinal phlebitis, as well as the evolution of the clinical picture with treatment. results/conclusions: the clinical diagnosis of ocular bartonellosis was serologically confirmed. oral treatment with ciprofloxacine healed the phlebitis and the neuroretinitis, with a residual optic disk pallor. this case exemplifies the d ... | 2003 | 12743848 |
| monoclonal and biclonal gammopathy in two patients infected with bartonella henselae. | two immunocompetent patients with cat-scratch disease due to infection with bartonella henselae developed monoclonal and biclonal gammopathy. neither patient had evidence of any other known cause of plasma cell dyscrasia, and antibiotic eradication of bartonella henselae infection resulted in the prompt disappearance of the gammopathy. hence, cat-scratch disease should be added to the list of possible underlying disorders in individuals presenting with monoclonal and biclonal gammopathy. | 2003 | 12764550 |
| lymphadenopathy at the medial epitrochlear region in cat-scratch disease. | our objective was to describe the imaging features of lymphadenopathy at the medial epitrochlear region as frequently seen in cat-scratch disease (csd) and to compare these features with those seen in non-csd. ten patients (four males and six females) presented with a subcutaneous soft tissue mass at the medial epitrochlear region. three patients were younger than 15 years. magnetic resonance imaging was performed in all patients. all lesions turned out to be regional lymphadenopathy instead of ... | 2003 | 12764654 |
| submacular exudates with serous retinal detachment caused by cat scratch disease. | to present submacular exudates as a manifestation of cat scratch disease. | 2002 | 12778351 |
| asking the right question. | 2003 | 12781538 | |
| cat-scratch disease occurring in three siblings simultaneously. | we report for the first time three siblings with cat-scratch disease occurring simultaneously. case 1 was an 8-year-old boy with enlarged supraclavicular lymph nodes and fever. case 2 was the 11-year-old sister whose presentation was a prolonged febrile illness. case 3 was a 13-year-old male adolescent with adenitis of the neck and thigh. all three patients were treated with rifampin with improvement of their symptoms. | 2003 | 12797315 |
| bartonella quintana and mycobacterium tuberculosis coinfection in an hiv-infected patient with lymphadenitis. | cat scratch disease (csd) is usually associated with bartonella henselae infection in patients with a history of cat exposure, but bartonella quintana may also be a cause of chronic lympadenopathy in patients with cat or flea contact. the lymph node histopathology of csd and tuberculosis may be indistinguishable. we report herein the first description of lymph node coinfection with b. quintana and m. tuberculosis in a 32-year hiv-infected woman. culture of lymph node biopsy material on columbia ... | 2003 | 12799150 |
| occurrence of bartonella henselae and bartonella quintana in a healthy greek population. | the purpose of this study was to determine the prevalence of igm and igg antibodies against bartonella henselae and b. quintana in a healthy greek population using a commercially available immunofluorescent test (focus test). five hundred healthy individuals were divided by sex into four age groups and three groups according to contact with cats. igm antibodies were not detected in any of the subjects examined, while 99 (19.8%) and 75 (15%) were igg seropositive to b. henselae and to b. quintana ... | 2003 | 12812344 |
| a case of cat scratch disease neuroretinitis confirmed by polymerase chain reaction. | cat scratch disease neuroretinitis is caused by infection by bartonella henselae. to demonstrate b. henselae infection, serologic examination is commonly used, but sometimes serologic examination is not adequate for correct diagnosis. here we present a case of cat scratch disease neuroretinitis confirmed by polymerase chain reaction in addition to serologic examination. | 2003 | 12842212 |
| osteomyelitis caused by bartonella henselae genotype i in an immunocompetent adult woman. | we report the first description of osteomyelitis due to bartonella henselae genotype i in an immunocompetent middle-aged woman. the diagnosis was established by serology, histopathology, and pcr analysis of osseous and lymph node tissues. the mycobacteria growth indicator tube inoculated with the lymph node aspirate was used for pcr analysis. | 2003 | 12843112 |
| detection by immunofluorescence assay of bartonella henselae in lymph nodes from patients with cat scratch disease. | laboratory diagnosis of bartonella henselae infections can be accomplished by serology or pcr assay on biopsy samples. the purpose of our work was to assess immunofluorescence detection (ifd) in lymph node smears using a specific monoclonal antibody directed against b. henselae and a commercial serology assay (ifa) compared with pcr detection. among 200 lymph nodes examined from immunocompetent patients, 54 were positive for b. henselae by pcr, of which 43 were also positive by ifd. among the 14 ... | 2003 | 12853405 |
| identification of rickettsia spp. and bartonella spp. in ffrom the thai-myanmar border. | during a survey for possible rickettsial vectors in villages of the central part of the thai-myanmar border from september 2001 to february 2002, four species of fleas were collected from common peridomestic animals. all fleas were tested by pcr to detect dna of bacteria of the genera rickettsia (glta and ompb genes) and bartonella (its and ftsz genes). sequencing of pcr-amplified products was done using glta fragments for rickettsia and ftsz fragments for bartonella: two genotypes related to ri ... | 2003 | 12860622 |
| genetic variation of bartonella henselae detected in lymph nodes from patients with cat scratch disease in slovenia. | 2003 | 12860661 | |
| cat scratch disease with lymphadenitis, vertebral osteomyelitis, and spleen abscesses. | in this report we describe a 30-year old male patient with vertebral osteomyelitis and spleen abscesses with cat scratch disease. the diagnosis was made on the basis of molecular detection of bartonella henselae either on lymph node biopsies or on bone biopsy, histology of the lymph node, serology using either our in-house microimmunofluorescence assay or a commercial kit (focus technologies). immunofluorescent detection was also performed directly on slide appositions using a monoclonal antibod ... | 2003 | 12860662 |
| bartonella henselae and borrelia burgdorferi infections of the central nervous system. | to investigate the role of b. henselae in patients with symptoms suggesting neuroborreliosis, serum and cerebrospinal fluid samples were tested with serological and pcr methods. among 17 examined patients, in 12 cases borrelia burgdorferi infections were detected, in 1 case bartonella henselae infection was ascertained, and in two patients mixed b. burgdorferi and b. henselae infections were found. these results indicate that mixed infections should be taken into consideration in establishing di ... | 2003 | 12860663 |
| seroprevalence of bartonella henselae and bartonella quintana infections in poland in 1998-2001. | 2003 | 12860664 | |
| first case in bulgaria of parinaud's oculoglandular syndrome associated with bartonella henselae. | 2003 | 12875532 | |
| cat scratch disease presenting as orbital abscess and osteomyelitis. | ocular manifestations of cat scratch disease are uncommon. the diagnosis is usually made on the basis of increasing bartonella henselae serum antibody titers. we report a child presenting with orbital abscess and osteomyelitis who was diagnosed with hepatosplenic cat scratch disease by detection of b. henselae dna in the orbital abscess fluid. | 2003 | 12904438 |
| prevalence of bartonella infection among human immunodeficiency virus-infected patients with fever. | bartonella infection can be difficult to diagnose, especially when it manifests as bacteremia, which is usually accompanied by nonspecific symptoms, such as fever. therefore, we hypothesized that bartonella infection represents an underrecognized cause of febrile illness. to determine the prevalence of bartonella infection among patients presenting with fever, we evaluated 382 patients in san francisco. overall, 68 patients (18%) had evidence of bartonella infection detected by culture, indirect ... | 2003 | 12905141 |
| the role of the host immune response in pathogenesis of bartonella henselae. | bartonella henselae can infect humans resulting in a wide range of disease syndromes including cat-scratch disease, fever with bacteremia, endocarditis, bacillary angiomatosis, and bacillary peliosis hepatis, among others. the nature and severity of the clinical presentation correlates well with the status of the hosts' immune system. individuals with impaired immune function, including hiv infection, progress to systemic infections more often. patients with intact immune function who become inf ... | 2003 | 12906736 |
| molecular cloning and analysis of a region of the bartonella bacilliformis genome encoding nlpd, l-isoaspartyl methyltransferase and yajc homologs. | the nlpd/lppb homolog of the human pathogen, bartonella bacilliformis, is an immunogenic 43-kda protein that is encoded by a 1206-bp open reading frame (orf-401). the regions flanking the nlpd/lppb gene of b. bacilliformis were sequenced to determine if it is located within the rpos operon, as it is in most bacteria. we report that the b. bacilliformis nlpd/lppb gene is located immediately downstream of pcm, a gene encoding a 25-kda protein, l-isoaspartyl protein carboxyl methyltransferase, that ... | 2003 | 12941162 |
| isolated splenic cat scratch disease. | 2003 | 12955654 | |
| rapid and efficient transposon mutagenesis of bartonella henselae by transposome technology. | molecular genetics are difficult to perform in bartonella henselae, the causative agent of cat scratch disease and the vasculoproliferative disorders bacillary angiomatosis and bacillary peliosis. to elucidate the underlying bacterial pathogenic mechanisms, genetic manipulation of b. henselae is the method of choice. we describe how to perform transposon mutagenesis in b. henselae using transposome technology. b. henselae mutants revealed by this technique showed random transpositional insertion ... | 2003 | 12957381 |
| cloning and expression of bartonella henselae sucb gene encoding an immunogenic dihydrolipoamide succinyltransferase homologous protein. | immunoscreening of a zap genomic library of bartonella henselae strain houston-1 expressed in escherichia coli resulted in the isolation of a clone containing 3.5 kb bamhi genomic dna fragment. this 3.5 kb dna fragment was found to contain a sequence of a gene encoding a protein with significant homology to the dihydrolipoamide succinyltransferase of brucella melitensis (sucb). subsequent cloning and dna sequence analysis revealed that the deduced amino acid sequence from the cloned gene showed ... | 2003 | 14524617 |
| long-term serological analysis and clinical follow-up of patients with cat scratch disease. | a highly specific enzyme immunoassay (eia) was recently described for use in the diagnosis of cat scratch disease (csd). however, data regarding eia antibody kinetics or its correlation with long-term clinical follow-up data are lacking. the association between antibody kinetics, clinical spectrum, and disease duration were studied in 98 patients with csd. the median duration of follow-up was 35.3 weeks (range, 2-211.3 weeks). results of eia testing for detection of anti-bartonella henselae immu ... | 2003 | 14557957 |
| conjunctival cat-scratch disease simulating rhabdomyosarcoma. | 2003 | 14560840 | |
| characterization of the natural population of bartonella henselae by multilocus sequence typing. | investigations of the population genetics of bartonella henselae have demonstrated a high level of diversity among strains, and the delineation of isolates into one of two subtypes, type i (houston) and type ii (marseille), represented by specific 16s ribosomal dna (rdna) sequences, has long been considered the most significant genotypic division within the species. this belief is challenged by recent work suggesting a role for horizontal gene exchange in generating intraspecies diversity. we at ... | 2003 | 14605141 |
| fatal case of endocarditis associated with bartonella henselae type i infection in a domestic cat. | we report the first feline case of bartonella henselae endocarditis. despite negative blood cultures, the cat had high bartonella antibody titers and b. henselae type i dna was detected in the damaged aortic valve. microscopic examination of the valve revealed endocarditis with small silver positive coccoid structures in endothelial cells. | 2003 | 14605199 |
| cat or dog ownership and seroprevalence of ehrlichiosis, q fever, and cat-scratch disease. | 2003 | 14609477 | |
| neuroretinitis associated with cat-scratch disease in japanese patients. | to clarify the prevalence and clinical profile of neuroretinitis associated with cat-scratch disease (csd) in japan. | 2003 | 14641271 |
| identification and characterization of the ddlb, ftsq and ftsa genes upstream of ftsz in bartonella bacilliformis and bartonella henselae. | homologues of the cell division protein ftsz were previously identified in bartonella bacilliformis and bartonella henselae. we report herein that ftsz is located at the distal end of an operon that includes ddlb, ftsq, and ftsa. these genes code for homologues of d-alanine d-alanine ligase, an enzyme involved in cell wall biosynthesis, and ftsq, and ftsa, which are involved in cell division. the ddlb, ftsq, and ftsa proteins from bartonella species are most homologous to proteins in closely rel ... | 2003 | 14659047 |
| high prevalence of antibodies to bartonella henselae among italian children without evidence of cat scratch disease. | few data are available on the seroprevalence of antibodies to bartonella henselae among children. we retrospectively evaluated the presence of immunoglobulin g and m class antibodies to b. henselae in 508 children living in central italy who were apparently free of any features suggesting b. henselae infection. we found that b. henselae infection is common among children in central italy, occurs early in life, is in most cases asymptomatic, and resolves spontaneously. | 2004 | 14679462 |
| causes of febrile illnesses after a tick bite in slovenian children. | to establish the etiology in slovenian children with febrile illnesses occurring after a tick bite. | 2003 | 14688569 |
| pathologic quiz case: a 17-year-old renal transplant patient with persistent fever, pancytopenia, and axillary lymphadenopathy. bacillary angiomatosis of the lymph node in the renal transplant recipient. | 2004 | 14692837 | |
| bartonella henselae infection associated with neuroretinitis, central retinal artery and vein occlusion, neovascular glaucoma, and severe vision loss. | to report a case of bartonella henselae infection. | 2004 | 14700670 |