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antibacterial and antifungal activity of avarone and avarol.the sesquiterpenoid hydroquinone and quinone, avarol and avarone, were previously found to be potent antitumor agents (müller et al., 1984). in the present study it is reported that in aqueous solution (ph 7.2), in the presence of dimethylsulfoxide, avarol is converted to avarone. avarone and to a smaller extent also avarol were active against a variety of grampositive bacterial species. the highest activity was determined for streptococcus pneumoniae and erysipelothrix rhusiopathiae (mic 0.781 ...19853841441
microsporum canis infection of the scalp in an adult. 19853856150
trichophyton rubrum specific ige in serum in patients with chronic t. rubrum infection as demonstrated by crossed radio-immuno-electrophoresis.by means of crossed radio-immunoelectrophoresis specific ige antibodies to trichophyton rubrum were demonstrated in serum from seven of eight patients with chronic t. rubrum infection. total ige values were within normal limits in all. in contrast, no specific ige antibodies were found in sera from 10 patients with inflammatory ringworm lesions due to microsporum canis, t. mentagrophytes or t. verrucosum or from six non infected controls. a long-lasting exposure to a constant antigen load is con ...19853869418
high-performance liquid chromatographic identification of beta-lactam antibiotics produced by dermatophytes.thirteen of 48 dermatophyte isolates were found by bioassay to produce beta-lactam antibiotics and seven produced other antibiotics. estimation and detection of specific beta-lactams in culture broths by derivatization and hplc was only possible following concentration and extraction procedures. analysis of the concentrated broths demonstrated the production of penicillin x and penicillin g by two trichophyton mentagrophytes strains and by one microsporum canis strain; one further t. mentagrophy ...19853878840
humoral immunofluorescent antibodies in subjects with dermatophytosis. 19853903493
brief communication: extracellular enzymatic activities of dermatophytes.eighty dermatophyte strains belonging to the genera trichophyton, microsporum, epidermophyton and chrysosporium were screened for their ability to produce extracellular enzymes using a semiquantitative method. the results obtained vary significantly when the studied genera are observed separately, though the enzyme beta-galactosidase was detected in none of the four studied genera.19853906403
[in vitro action of a new antifungal agent, naftifine, on dermatophytes].naftifine is a new antifungal agent derived from naphtalenemethane amine and highly active in vitro against dermatophytes. we studied this action against more than 100 strains belonging to 16 different species of the trichophyton, microsporum and epidermophyton genera. mics were determined in a liquid or solid medium using yma and ymb sabouraud broths. yeasts (candida, torulopsis) and certain molds such as scopulariopsis brevicaulis showed little susceptibility. in contrast, mics for dermatophyt ...19853911160
serological analysis of dermatophyte isolates with monoclonal antibodies produced against microsporum canis.hybridoma cells produced by fusing myeloma cells with spleen cells from mice immunized with a soluble antigen of microsporum canis yielded 30 antibody-producing clones. six of these clones, propagated as ascites tumors in mice, showed two different types of monoclonal antibodies. the type 1 monoclonal antibody reacted with 17 heterologous and 10 homologous dermatophyte antigens. type 2 monoclonal antibodies were unable to precipitate three antigens from different isolates of m. canis, thus sugge ...19853918075
lipids of dermatophytes ii. effect of growth condition on the lipid composition and membrane transport of microsporum gypseum.supplementation of glucose-containing medium with ethanol and replacement of glucose by glycerol in the sabouraud's growth medium of microsporum gypseum altered the levels of total phospholipids as well as their apolar and polar head groups. the levels of phosphatidylcholine (pc) and phosphatidylethanolamine (pe) increased under these growth conditions; also, the ratio of unsaturated/saturated phospholipid fatty acids decreased on ethanol supplementation but increased in the presence of glycerol ...19853918228
[disinfection for dermatomycoses in veterinary practice].sporulating cultures of two strains of trichophyton equinum, two strains of trich. mentagrophytes and one strain of microsporum canis were tested by a simple dipping technique for their sensitivity to ten currently used disinfectants. antifungal effects on all cultures of dermatophytes were observed already after one-minute treatment with 0.5%-4% peracetic acid, 4% formaldehyde solution and concentrated solution of lastanox super. the above strains were inactivated after five-minute treatment wi ...19853919486
metabolism of sulfur-containing amino acids in the dermatophyte microsporum gypseum. ii. acidic amino acid derivatives.the dermatophyte microsporum gypseum was cultivated on a glucose-arginine medium supplemented with five strongly acidic derivatives of cysteine (l-cysteine sulfinic acid, l-cysteic acid, l-serine-o-sulfate and taurine at a concentration of 5 mmol/l, and l-s-sulfocysteine at a concentration of 2.5 mmol/l). the addition of these substances did not stimulate the growth as compared with the control containing 0.5 mmol/l cystine. cysteine sulfinic acid and cysteic acid showed rather inhibitory effect ...19853925121
antigenic characterization of microsporum canis, m. distortum, m. equinum, m. ferrugineum and trichophyton soudanense cultures.the authors investigated the antigenic properties of a group of closely related dermatophytes whose components may be morphologically confused with one another: microsporum canis, m. distortum, m. equinum, m. ferrugineum and trichophyton soudanense. by using reference antigens and adsorbed monospecific antisera, it was possible to serologically distinguish the reference strains by the exoantigen technique. their common and specific antigenic determinants were visualized by cross-immunoelectropho ...19853934539
zoonotic dermatophytosis (ringworm) 19863952959
fine structure and development of pilosporella chapmani (microspora: thelohaniidae) in the mosquito, aedes triseriatus (say).new information on the life cycle and fine structure of pilosporella chapmani, a microsporidium of the mosquito aedes triseriatus, is presented. pilosporella chapmani is shown to have two sporulation sequences, one of them being involved in transovarial transmission. one sequence, involving meiosis and production of a moniliform sporogonial plasmodium, occurs in the larval fat body, resulting in eight uninucleate, spherical, and fully developed spores. the other occurs in oenocytes of adult mosq ...19863959008
antifungal activity of some mediterranean algae.the antifungal activity of 15 mediterranean algae species on some dermatophyte strains (epidermophyton floccosum, microsporum canis, m. gypseum and trichophyton mentagrophytes) and pathogenic yeasts (candida albicans, c. guillermondii, c. krusei, c. tropicalis and torulopsis glabrata) has been tested following a modification of aubert's technique. among the algae species studied, falkenbergia rufolanosa is the most active in front of all the fungi tested.19863960102
studies on haemagglutinins of microsporum gypseum. 19853982449
studies on the prevalence of tinea capitis infection in ile-ife, nigeria.investigations were carried out into the prevalence of tinea capitis infection among school children in ile-ife, nigeria. the prevalence rate of clinical infection was found to be 14.02%. the infection was found to be more frequent among pupils between ages 5 and 10 years, and more prevalent among the poor than the rich (p less than 0.005). families having between 1 and 4 children had lower prevalence than families having minimum of five children (p less than 0.10). approximately one-third of th ...19853982491
[mycological findings in andrological patients. statistical study in the years 1971-1981].in the years 1971 to 1981, clinical signs of mycotic skin infection were found in 589 andrological patients (2.7%). microscopic proof and absence of positive microscopic results, respectively, are not sufficient for diagnosis; therefore, the culture is a conditio sine qua non for exact diagnosis. a positive mycotic culture was found in 13% of the cases with a negative microscopic investigation.19853984428
tinea capitis: current concepts.tinea capitis is still with us. the hair has been beaten into submission by irradiation in past years; the organisms have been beaten into submission with griseofulvin and other agents; yet the disease lives on. we thought it appropriate to have a symposium on the subject of the epidemiology of tinea capitis, its changing nature, its complications, the carrier state, differential diagnosis, culture techniques, and the current status of the management of its various causes. as one of our authors ...19853991378
[tinea caused by microsporum canis in children under 30 days of age].six cases of ringworm due to microsporum canis are reported in infants no more than 30 days old. the infections came from cats. the patients responded to therapy with griseofulvin and tolnaftate, miconazole or iodine.19853992426
metabolism of sulfur-containing amino acids in the dermatophyte microsporum gypseum. i. neutral amino acids.the dermatophyte microsporum gypseum was cultivated on a glucose-arginine medium to which on out of six sulfur-containing amino acids was added (l-cystine, l-djenkolic acid, dl-lanthionine dl-homocystine, l-methionine, or l-methionine-sulfone at a concentration of 5 mm with respect to sulfur content). the addition of these substances did not stimulate the growth and some amino acids (djenkolic acid and particularly methionine and methionine-sulfone) were inhibitory. all tested compounds were uti ...19853998995
an experimental model for transepidermal elimination of a dermatophytic granuloma. 19854000183
epidemiological trends of dermatophytoses and dermatophytes in jerusalem between 1954 and 1981.data for dermatophyte infections analysed for five 3-year periods between 1954 to 1981 led to the following conclusions: tinea pedis, tinea cruris and tinea manuum showed an increase in the 50's and 60's and declined in the 70's; tinea unguium and tinea corporis showed an increase during the whole period; at all these sites, the percentage of trichophyton rubrum, the main etiologic agent, increased steadily over the periods while the percentage of trichophyton mentagrophytes, the secondary etiol ...19854010765
granuloma and pseudogranuloma of the skin due to microsporum canis. successful management with local injections of miconazole.a 25-year-old immunosuppressed woman with systemic lupus erythematosus experienced a chronic cutaneous and subcutaneous infection due to microsporum canis. the clinical course and response to therapy of this extremely rare form of dermatophytosis are described.19854015135
isolation of dermatophytes from domestic animals in norway.the examination of 2066 skin scrapings from domestic animals in the period from july 1981 to june 1984, revealed dermatophytes in 439 samples. dermatophytes isolated were: m. canis in dog, cat, cattle, horse, swine, goat, rabbit and hamster, m. equinum in dog and horse, m. gypseum in horse, t. equinum in horse and cattle, t. mentagrophytes in dog, cat, cattle, horse, guinea pig and rabbit, t. verrucosum in cattle and e. floccosum in dog.19854034390
[unusual localization of glabrous skin microsporosis caused by microsporum canis]. 19854036300
the spiral organ of dermatophytes. 19854039034
treatment with enilconazole spray of dermatophytosis in rabbit farms. 19854047095
disturbances in toxicological experiments caused by microsporum canis.cutaneous lesions which can lead to false positive results have been observed in several rabbits used for the determination of the cutaneous irritation capacity of a product (ita, pii). the responsible agent was microsporum canis. a preventive treatment by an antifungal agent did not modify toxicological experimental results.19854047130
scanning and transmission electron microscopy: study of effects of econazole on microsporum canis.microsporum canis is a frequent dermatophyte in france, and causes tinea and herpes circinatus in children. this work shows the superficial and ultrastructural alterations induced by econazole nitrate on this fungus.19854058564
treatment of tinea corporis or tinea cruris with bifonazole 1% gel: an open, multicentre study.an open, multicentre study was carried out in 103 patients with confirmed dermatophyte infections (tinea cruris or tinea corporis). the fungi isolated were tr. rubrum (45), tr. mentagrophytes (11), ep. floccosum (26) and m. canis (21). all patients were treated with a single daily application of bifonazole (1% gel) and the duration of treatment was 3 weeks. weekly clinical controls were performed during the therapeutic period and at least two clinical and mycological examinations were given afte ...19854059289
microsporid gonitis caused by microsporum nanum.the mycid reaction in the form of exudative gonarthritis was observed in the case of a 65-year-old farmer suffering from a profound mycosis of the chin.19854069191
human plasma and skin blister fluid levels of griseofulvin after its repeated administration.griseofulvin was administered orally to 6 healthy volunteers for 6 days. the subjects received 500 mg of a microsize formulation and 330 mg of an ultramicrosize formulation, according to a cross-over design. the drug was determined in plasma, suction blister fluid (sbf) and cantharides blister fluid (cbf) following the last dose. urinary excretion of the main metabolites 6-demethylgriseofulvin (6-dmg) and its glucuronic acid conjugate was also measured. the pharmacokinetic parameters were compar ...19854076331
existence of ornamentations on macroconidia and hyphae of epidermophyton floccosum.the surface features of cell walls of several recent clinical isolates of epidermophyton floccosum were examined by scanning electron microscopy. macroconidia from each of our isolates displayed excrescences on the wall which were similar in their location and in their substructural appearance. we believe these irregularities sufficiently developed to regard them as true wall ornamentations. comparisons were made with wall features of the macroconidia of microsporum persicolor. in some cases, ou ...19854083834
[results of the scientific work in mycology at a city dermatology and venereology dispensary (1971-1984)]. 19854090704
[a dermatophyte, microsporum canis bodin, 1902, isolated from the soil in yugoslavia].microsporum canis (bodin, 1902) has been revealed from samples of soil by using the method of r. vanbreuseghem. this fungus was identified on the ground of microscopical examination of the cultures, which showed typical macronidia. this is first communication about fungus in yugoslavia.19854091622
[topochemical studies of hair decomposition by dermatophytes in vitro. ii. study of single reactive groups]. 19684097512
morphological and cytological observations on conidial formation of the genera epidermophyton and microsporon. 19714108545
microsporum gypseum macroconidial development revealed by transmission and scanning electron microscopy. 19724112143
thiosulphate esters in keratin attacked by dermatophytes in vitro. 19724112144
double-blind trial of miconzole in dermatomycosis. 19734129601
immunology of dermatophytes and dermatophytosis. 19744134809
letter: activity of silver sulphadiazine against dermatophytes. 19744137746
distribution of nuclei in macroconidia of dermatophytes. 19744140133
effect of growth-regulating substances on the biomass and lipids of some fungi. 19724144936
[effect of griseofulvin on the activity of certain enzymes the serum polarograms in trichophytosis and microsporosis]. 19734149874
growth and extracellular lipids of certain pathogenic fungi in presence of different concentrations of amino acids. 19744151215
effect of amino acids on the growth and phospholipid composition of some pathogenic fungi. 19744155857
microsporon canis--an actual cause of ringworm in sweden. 19654162873
[on a method of microcultivation of the perfect stage of microsporum gypseum (bodin) guiart & grigoraki and the staining of the ascospores]. 19664166766
[on the enzyme histochemistry of dermatophytes. ii. changes in the outcome of enzymatic reactions following the effect of griseofulvin]. 19664167483
[studies of the vitality of dermatophytes in the soil]. 19664167536
[on enzyme histochemistry of dermatophytes. i. localization, distribution and intensity of enzymatic reactions]. 19664169210
[application of the fluorescent microscopy method for studies on fungi]. 19674171037
keratinophilic fungi in the soil of the danube delta. 19684174101
[on the stainable hydrolases determination in dermatophytes and molds]. 19674174621
geophilic dermatophytes in the soil in sweden. studies on their occurrence and pathogenic properties. 19684179998
[nuclear staining of dermatophytes]. 19684182105
[suggestions for the improvement of the agar block method]. 19674186719
biochemical changes during fungal sporulation and spore germination. i. phenyl methyl sulfonyl fluoride inhibition of macroconidial germination in microsporum gypseum.macroconidia of microsporum gypseum release free amino acids into the medium during germination. a single alkaline protease is also found in the germination supernatant fraction. the purified protease is capable of hydrolyzing isolated spore coats in vitro. phenyl methyl sulfonyl fluoride (pmsf) is an effective inhibitor of the protease. incorporation of pmsf at 10(-4)m into the germination system inhibits spore germination and the release of free amino nitrogen. addition of pmsf after germ tube ...19704191321
microsporum rivalieri isolated from tinea capitis in east anglia (england). 19704193475
oxidation of furans. 2. synthesis and biological properties of 6-hydroxy-2h-pyran-3(6h)-ones and derivatives. 19734201420
[microsporia of cats and dogs caused by the dermatophyte microsporum canis bodin]. 19744210144
[nail fungus types in the area of plovdiv, bulgaria]. 19654221152
[experience in microsporosis control]. 19654222636
[onychomycosis and other dermatomycoses caused by microsporum gypseum in hungary]. 19654223189
human dermatophyte infections from laboratory animals. 19654225035
[microsporia of the nail]. 19664229876
superficial dermatomycoses in bangkok, thailand. 19674231063
[on the current state of dermatophytes in rumania]. 19684233080
[comparative epidemiological studies of dermatomycoses in the cities of wurzburg and bonn and their watershed. 1]. 19674233260
[thoughts and proposals for a uniform statistical compilation of the dermatomycoses and of their agents in germany]. 19674233309
comparative studies on the enzyme-histochemical behaviour of some dermatophytes. i. in vitro investigations (saprophytic biophase). 19684234245
[enhancement of the antimycetic effictiveness of griseofulvin by dimethylsulfoxide in vitro]. 19684235699
occurrence of dermatophytes in bangkok, thialand. 19684235795
[microflora of patients with dermatomycoses in the andizhan district of uzbekistan]. 19674236092
[contribution to the epidemiology of trichophytosis caused by trichophyton verrucosum (faviforme)]. 19694240003
[effect of persteril on dermatophytes]. 19694240929
[etiology and epidemiology of dermatophytic onychoses]. 19694244958
incidence of dermatophytosis in ahmedabad (gujarat). 19694245909
[sensitivity of inbred mouse strains to experimental infection caused by dermatophytes]. 19704247898
[combined dermatophytic nail infection due to microsporum ferrugineum and trichophyton rubrum]. 19714251341
[rare dermatophytic causative agents of nail mycoses: trichophyton schönleinii, trichophyton verrucosum, microsporum canis and microsporum gypseum]. 19714251342
[the dynamics of the agents of mycoses of the scalp in the udmurt assr (1959-1968)]. 19704252656
[antimicrobial activity of broad-spectrum antimicrobial agents, with special reference to salicylic acid]. 19714253298
studies of allergy to penicillin in the course of dermatomycoses. 19714255662
microsporum spp. in tinea pedis. 19714255774
a short review on the onychomycoses by dermatophytes in romania. 19714256914
dermatomycoses in fur animals: chinchilla, ferret, mink and rabbit. 19724257259
[clinical and epidemiological features of microsporosis in minsk]. 19714257316
keratophilic fungi and the prevalence of dermatomycoses in orissa, india. 19724264407
biochemical studies of pigments from the pathogenic fungus, microsporum cookei. 19734271697
superficial fungus infections. 19744272311
ringworm in the south-west of england, 1960-1970, with special reference to onychomycosis. 19744272848
[human infections due to microsporum gypseum in the canton of vaud, switzerland]. 19744274763
[dermatophytoses. mycoses of the skin due to dermatophytes]. 19744277164
[terpenes and terpene derivatives of carvone--and camphor type--their antimicrobial and verminoxious properties]. 19744277285
[evaluation of mycological laboratory data in dermatology (author's transl)]. 19744278801
frequency of occurrence of principal dermatophytoses and their causative agents observed in mexico city. 19744279055
[studies on the phosphate metabolism of dermatomyces]. 19664292098
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