Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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detection of an intracellular transforming protein (v-ki-ras p21) using the flow activated cell sorter (facs). | the transforming protein coded for by the ki-ras oncogene, v-p21, localizes at the cytoplasmic face of the plasma membrane. a method is presented whereby the appearance of v-p21 in kirsten murine sarcoma virus-transformed cells can be detected by flow cytometry, using a monoclonal antibody to v-p21 and methods modified from immunofluorescence microscopy. the method is sufficiently sensitive to differentiate between cellular and viral p21 levels, to detect small subpopulations of virus-transforme ... | 1986 | 3490470 |
electric field-mediated gene transfer (electroporation) into mouse friend and human k562 erythroleukemic cells. | electroporation, the technique of electric field mediated gene transfer, was evaluated as a means of introducing and expressing genes into mouse friend and human k562 erythroleukemic cells. long-term (stable) gene expression in both friend and k562 cells was measured using the recombinant plasmid homer 6, which carries the aminoglycoside phosphotransferase (aph) gene as a selectable marker under the transcriptional control of the moloney murine sarcoma virus long terminal repeat promoter/enhance ... | 1987 | 3507389 |
expression of p21 ras oncoproteins in human cancers. | the expression of proteins encoded by ras oncogenes was examined in 52 fresh human tumors of 19 different types using antibodies generated to different peptide domains of ras proteins of molecular weight 21,000 (p21). proteins related to ras genes were detected in 90% of tested tumors. in 21% of tumors there were high levels of ras p21 of greater than 40% of the level in a harvey murine sarcoma virus transformed cell line. predominance of either cellular ha-ras or other ras p21s was found in 20 ... | 1986 | 3510727 |
altered metabolism and cell surface expression of glycosphingolipids caused by vitamin e in cultured murine (k3t3) reticulum sarcoma cells. | vitamin e caused a generalized reduction in the metabolism and cell surface expression of glycosphingolipids (gsl) in cultured kirsten murine sarcoma virus-transformed nonproducer (k3t3) cells. metabolism of gangliosides was decreased two- to fourfold in cells treated for 72 hr with 1 and 2 micrograms/ml but not with 12 micrograms/ml vitamin e compared to control cultures. this was demonstrated by a quantitative reduction in precursor 3h-galactose label incorporated in ganglioside fraction and f ... | 1986 | 3540508 |
insulin stimulates the phosphorylation level of v-ha-ras protein in membrane fraction. | insulin was found to stimulate the phosphorylation of the 21,000-dalton protein encoded by the ras oncogene of harvey murine sarcoma virus in membrane fraction both in vivo and in vitro. when the human ras proteins expressed in e. coli were reconstituted with purified human insulin receptor, gtpase activity of normal or its mutated oncogenic ras protein was not stimulated by the addition of insulin. likewise, tyrosine kinase activity or insulin binding capacity of the receptor was not influenced ... | 1987 | 3555484 |
lactate dehydrogenase-elevating virus induces anti-golgi apparatus antibodies. | a recently described autoantibody-inducing agent in mice was further characterized. tentatively designated agia (anti-golgi apparatus-inducing agent), this agent has previously been shown to cause antibody production against golgi apparatus (ga) antigen of cells from different vertebrate species as well as against tumour surface antigen of the moloney murine sarcoma virus-non-producer transformant sac. it was shown to possess the properties characteristic of lactate dehydrogenase-elevating virus ... | 1987 | 3598563 |
human epidermal keratinocytes retain radiation resistance following in vitro immortalization and malignant transformation. | the radiobiology of human tumors suggests that multiple factors are involved in clinical radioresponsiveness. to date, no direct experimental evidence is available to correlate intrinsic cellular radiosensitivity with the steps of malignant transformation. we developed an in vitro multistage model of epithelial neoplasia using human epidermal keratinocytes to examine the effects of malignant transformation on radiation response. these cells were first immortalized as a result of infection with a ... | 1987 | 3659288 |
revertants of v-fos-transformed fibroblasts have mutations in cellular genes essential for transformation by other oncogenes. | morphologic revertants of fbj murine sarcoma virus (v-fos)-transformed rat-1 fibroblasts were isolated using a novel selection procedure based on prolonged retention of rhodamine 123 within mitochondria of v-fos-transformed versus normal fibroblasts. two classes of revertants were isolated: class i revertants have sustained mutations in cellular genes, and a class ii revertant has a nonfunctional v-fos provirus. somatic-cell hybridization studies suggested that the revertant phenotype was recess ... | 1987 | 3664639 |
effects of ouabain on nih/3t3 cells transformed with retroviral oncogenes and on human tumor cell lines. | both murine and human cell lines transformed by the v-ki-ras gene have been shown to be much more sensitive to the toxic effects of the cardiac glycoside ouabain than their respective controls. this differential toxicity has previously been used in the isolation of flat revertant clones from populations of kirsten murine sarcoma virus transformed nih/3t3 cells. here, we have undertaken a further characterization of this phenomenon in murine and human tumor cells. two different techniques, a 51cr ... | 1987 | 3679592 |
expression of c-mos proto-oncogene in undifferentiated teratocarcinoma cells. | proto-oncogene c-mos, the cellular homologue of the transforming gene of moloney murine sarcoma virus, has been characterized by the lack of expression in a variety of differentiated tissues, possibly because of the existence of an inhibitory upstream sequence. we detected mos-related transcripts in undifferentiated embryonal carcinoma cells of pluripotential cell line 311. the sizes of three major transcripts detected were estimated to be 1.8, 4.6 and 6.1-kilobases (kb) by northern analysis. fu ... | 2013 | 3778463 |
pathogenicity of retroviruses containing either the normal human c-ha-ras1 gene or its mutated form derived from the bladder carcinoma ej/t24 cell line. | cellular ras oncogenes transduced by retroviruses carry mutations in amino acids 12, 59 and 122. similar mutations have been observed in ras oncogenes activated during induction of neoplasia in both humans and experimental animals. the unmutated normal rat or human c-ha-ras-1 genes have the ability to transform nih 3t3 cells in culture when activated by a rna synthesis promoter. these findings raise the question of whether the mutations are necessary for the ras oncogenes to induce the neoplasti ... | 1985 | 3842394 |
efficient transcription of a protein-coding gene from the rna polymerase i promoter in transfected cells. | the activity of the mouse ribosomal promoter was examined after fusion to the gene coding for chloramphenicol acetyltransferase (cat) and transfection into mouse cells. very little cat enzyme but high levels of cat-specific rna correctly initiated at the ribosomal dna start site were synthesized. the amount of specific transcripts was neither influenced by long stretches of upstream spacer sequences nor by the insertion of the moloney murine sarcoma virus enhancer. the deletion mutant pmr delta- ... | 1985 | 3856225 |
infectivity of friend murine leukemia virus for hamster cells. | hamster-adapted friend murine leukemia virus (f-mulv) infected hamster cells and produced an xc-positive progeny. however, the sensitivity of hamster-adapted f-mulv's to hamster cells was about 100 times lower than that to mouse cells. hamster cells chronically infected with f-mulv in vitro produced progeny virus in titers comparable to those in similarly infected mouse cells. xenotropic and amphotropic murine leukemia virus can infect hamster cells when phenotypically mixed with the f-mulv. mur ... | 1985 | 3857383 |
plasmid-induced "hit-and-run" tumorigenesis in chinese hamster embryo fibroblast (chef) cells. | the chinese hamster embryo fibroblast cell line chef/18 is readily transfected by plasmid dna. in the present transfection studies with chef/18 cells, focus formation induced by plasmids containing the mutant human c-ha-ras gene ej was compared with that of control plasmids without the ej insert. the focus-forming activity of the transfected plasmid j132, a recombinant of the harvey murine sarcoma virus ltr and the normal human c-ha-ras1 in pbr322, also was assessed. foci were recovered after tr ... | 1985 | 3857618 |
t-cell regulation of erythropoiesis during acute lymphoblastic leukemia. | how and where erythropoiesis is maintained during advanced leukemic disease is an important and, as yet, unresolved question in hematology. to address the potential role of t-lymphocytes as cells that regulate cfu-e differentiation during leukemogenesis, an experimental model of disease has been developed in inbred balb/c mice. specifically, three-week-old balb/c by mice were injected with murine sarcoma virus-murine leukemia virus-moloney (msv-mulv-m), which resulted 6-8 months later in the dev ... | 1985 | 3871705 |
transformation of mononuclear phagocytes in vivo and malignant histiocytosis caused by a novel murine spleen focus-forming virus. | the study of retrovirus-induced leukaemias in mice is a powerful tool for the elucidation of the normal regulation of the haematopoietic system. the acute murine spleen focus-forming viruses (sffv) can be classified according to the haematopoietic lineage on which they exert their effects in the adult mouse. here we report a new sffv isolate, the af-1 virus, with the novel ability to transform cells of the mononuclear phagocyte lineage. the virus was isolated from sarcomas that were induced on p ... | 1985 | 3873013 |
characterization of gp85gag as an antigen recognized by moloney leukemia virus-specific cytolytic t cell clones that function in vivo. | the gag membrane protein gp85gag, encoded by moloney murine leukemia virus (m-mlv), was identified as a target molecule recognized by moloney murine sarcoma virus--m-mlv (m-msv--m-mlv)-specific cytolytic t lymphocyte (ctl) clones. target cells infected with ab-x-mlv, an m-mlv-derived mutant virus not encoding gp85gag, were not lysed by the ctl clones. the same ctl clones were shown previously to induce the destruction of m-mlv-induced tumor cells in the peritoneal cavity. we have now characteriz ... | 1985 | 3891902 |
product of the cellular oncogene, c-fos, observed in mouse and human tissues using an antibody to a synthetic peptide. | the transforming gene of the osteosarcoma-producing fbj murine sarcoma virus, v-fos, is homologous to a normal cellular gene, c-fos, in vertebrate species. transcripts from the c-fos proto-oncogene accumulate to very high levels in late gestational mouse and human extra-embryonic tissues. we now report that these rna transcripts are translated in these tissues. rabbits were immunized with a synthetic peptide whose sequence is common to both c-fos and v-fos. after affinity purification on an immu ... | 1985 | 3894012 |
p21ras. heterogeneous localization in transformed cells. | the cellular targets for the kirsten murine sarcoma virus (kimsv)-transforming protein, p21ras, are unknown. other studies have indicated that the mature form of p21 is distributed diffusely on the cytoplasmic face of the plasma membrane. however, after fixation without buffer washes, indirect immunofluorescent staining of sparse cultures revealed a particularly well preserved cellular architecture and a strikingly heterogeneous subcellular distribution of p21 in transformed normal rat kidney (n ... | 1985 | 3896830 |
expression of intact ki-ras p21 protein in escherichia coli. | we have constructed recombinant plasmids capable of expressing in escherichia coli the intact ras p21 protein encoded by kirsten murine sarcoma virus. the ki-ras gene was inserted into an expression vector carrying the e. coli tryptophan promoter and e. coli lipoprotein transcriptional terminator. the resulting plasmids direct the synthesis of large quantities of p21 protein, which represented 20% of the total cellular protein. the ki-ras p21 protein is immunoprecipitated with monoclonal antibod ... | 1985 | 3904744 |
the mitogenic/oncogenic p21 ki-ras protein stimulates adenylate cyclase activity early in the g1 phase of nrk rat kidney cells. | tsk-nrk rat cells infected with a temperature-sensitive mutant of the kirsten murine sarcoma virus were arrested in the g0/g1 phase of their cell cycle by incubation in serum-deficient medium at a temperature (41 degrees c) which inactivates the virus' abnormally thermolabile mitogenic/oncogenic 21 kda (p 21) ras protein product. reactivating the viral ras protein by lowering the temperature to a permissive 36 degrees c rapidly (within 1 hour) stimulated adenylate cyclase, sensitized the enzyme ... | 1985 | 3904756 |
characterization and developmental expression of a drosophila ras oncogene. | we cloned a drosophila melanogaster ras gene (dmras64b) on the basis of its homology to the ras oncogen from harvey murine sarcoma virus. this gene mapped at chromosomal position 64b on the left arm of the third chromosome. sequencing of dmras64b revealed extensive amino acid homology with the proteins encoded by the human and saccharomyces cerevisiae ras genes. the coding region of the drosophila gene is interrupted by two introns located in different positions with respect to its human counter ... | 1985 | 3921827 |
the ras oncogene product p21 is not a regulatory component of adenylate cyclase. | harvey (ha-msv) and kirsten (ki-msv) murine sarcoma viruses induce tumours in animals and transform various cells in culture because of the expression of the ras oncogene product, p21 (ref. 1). proto-oncogenes homologous with these genes are highly conserved evolutionarily and activated ras oncogenes have been detected in many human cancers. whether c-ras oncogenes are directly responsible for human carcinogenesis is uncertain; however, it is clear that p21 mediates virus-induced transformation, ... | 1985 | 3929144 |
anti-tumour effect of humoral and cellular immunities mediated by a bacterial immunopotentiator, lactobacillus casei, in mice. | administration of a mixture containing lactobacillus casei yit 9018 (lc9018) and methylcholanthrene-induced fibrosarcoma (meth a) cells into the peritoneum of syngeneic balb/c mice suppressed the tumour growth and protected the mice from tumour death. with the appearance of the anti-tumour activity, serum complement-dependent tumour cytotoxic (cdc) antibody was induced on the 5th day after the administration as a result of the adjuvant effect. the cytotoxic antibody was not found in serum on the ... | 1985 | 3930065 |
[fatty acid content in the muscles and liver of mice developing sarcomas induced by 3-methylcholanthrene and moloney murine sarcoma virus]. | a comparative analysis was made for the fatty acid composition of lipids in the malignant muscular tissue, muscle and liver under blastomogenesis induced in mice by the moloney sarcoma virus and 3-methylcholanthrene. the relation of the found changes in the fatty acid composition to the blastomogenesis stages is shown. the development of the tumour node is accompanied by a decrease of the fatty acid amount in the animal tissues and by its increase in the tumour. a spontaneous regression of the m ... | 1986 | 3948758 |
multistep process of neoplastic transformation of normal human fibroblasts by 60co gamma rays and harvey sarcoma viruses. | as reported previously (namba et al., 1985), normal human fibroblasts were transformed by 60co gamma-ray irradiation into immortal cells with abnormal karyotypes. these transformed cells (kmst-6), however, showed a low cloning efficiency in soft agar and no transplantability. however, upon treatment with harvey murine sarcoma virus (ha-msv), the cells acquired elevated clonability in soft agar and transplantability in nude mice. ha-msv alone, however, did not convert normal human fibroblasts int ... | 1986 | 3949423 |
mmc-e cells--origin and changes in karyotype accompanying malignant transformation. | karyotype analysis of an established nontumorigenic cell line (mmc-e) indicated that the cells are of rat origin instead of mouse, as interpreted earlier. this cell line, now termed re (rat epithelial) had a karyotype of 39,x,-5,-15,-?16,+t(3q11q) in the stem line. there was also one subline that had a karyotype of 40,x,-5,-15,-?16,+t(3q11q), +?t(5;?). chromosome changes and frequency of sister chromatid exchanges (sces) were studied from seven malignantly transformed re cell lines. these includ ... | 1985 | 3971317 |
transformation of human bronchial epithelial cells transfected by harvey ras oncogene. | transfection of normal human bronchial epithelial (nhbe) cells with a plasmid carrying the ras oncogene of harvey murine sarcoma virus (v-ha ras) changed the growth requirements, terminal differentiation, and tumorigenicity of the recipient cells. one of the cell lines isolated after transfection (tbe-1) was studied extensively and shown to contain v-ha ras dna. total cellular rna from tbe-1 cells hybridized to v-ha ras structural gene fragment probes five to eight times more than rna from paren ... | 1985 | 3975607 |
expression of c-mos proto-oncogene transcripts in mouse tissues. | valuable information about proto-oncogenes and their physiological function has been obtained by studying their expression in normal cells. however, expression of the c-mos gene, the cellular homologue of the transforming gene of moloney murine sarcoma virus, has not been detected in normal mouse cells or tissues. the conservation of the c-mos open reading frame strongly indicates that the gene must function during some portion of the animal life cycle, and other lines of evidence suggested to u ... | 1985 | 4000280 |
expression of glucagon sensitivity by transformed mdck cells normally unresponsive to glucagon: early commitment to differentiation. | a cloned line of canine kidney cells (mdck) transformed with harvey murine sarcoma virus, in contrast to the parental, untransformed line, expressed glucagon sensitivity only under controlled culture conditions. the glucagon sensitivity of transformed mdck cells appeared after 10 days of culture if plated at less than 100,000 cells/dish or after 3 days if cells were plated at greater than 300,000 cells/dish. as there was no effect of conditioned medium from glucagon-sensitive cells on insensitiv ... | 1985 | 4055913 |
depressed interferon synthesis in skin fibroblasts from lung cancer patients. | skin fibroblast cell cultures, derived from male adult lung cancer patients, an adult control population, and a newborn population were examined for their susceptibility to transformation with kirsten murine sarcoma virus and their ability to respond to an interferon inducer (poly i x poly c). an association between sensitivity to viral transformation and induction of interferon was observed. cultures derived from lung cancer patients demonstrated an increased sensitivity to virus transformation ... | 1985 | 4056491 |
sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line. | the growth-promoting and/or differentiation-blocking activities of kirsten (ki-msv) or harvey murine sarcoma virus (ha-msv) on various types of cells in vitro are well documented. here we report an unexpected effect of these viruses on a rat phaeochromocytoma cell line, pc12. pc12 cells, which multiply indefinitely in growth medium, are known to respond to nerve growth factor (ngf) by cessation of cell division and expression of several properties resembling those of differentiated sympathetic n ... | 1985 | 4058592 |
characteristics of 30-, 63-, and 89-kilodalton proteins whose secretion from mouse fibroblasts is altered by beta-interferon. | quiescent mouse balb/c-3t3 cells were treated with beta-interferon to induce the secretion of proteins of 30 and 89 kda and with a platelet-derived growth factor preparation to induce the secretion of a 63-kda protein. to label the secreted proteins the cultures were supplemented with [35s]methionine after addition of the inducer. the proteins in the culture fluid were fractionated resulting in a radioactively pure 63-kda protein and 30- and 89-kda protein preparations with residual minor radioa ... | 1985 | 4066715 |
alterations in the susceptibility of cultured mouse cells to transformation by murine sarcoma virus (harvey). | 1971 | 4107845 | |
rifamycin derivatives strongly inhibiting rna leads to dna polymerase (reverse transcriptase) of murine sarcoma viruses. | 1972 | 4114001 | |
revertants of mouse cells transformed by murine sarcoma virus. i. characterization of flat and transformed sublines without a rescuable murine sarcoma virus. | 1972 | 4117128 | |
isolation of temperature-sensitive mutants of murine sarcoma virus. | three separate murine sarcoma virus nonproducer cell lines have been isolated which are temperature sensitive for the maintenance of transformation. in each case, a viral rather than a cellular genetic mutation is the reason for the temperature-sensitive effect. superinfection of one of the mutants with murine leukemia virus overcomes the temperature-sensitive change in the transformed state. | 1972 | 4117345 |
major group-specific protein of rat type c viruses. | the major internal protein of a rat type c virus pseudotype of murine sarcoma virus, msv(ralv), was purified by isoelectric focusing (pi = 8.6) and used to prepare antibody in guinea pigs. the protein was identified by its reaction with antisera reactive with the mammalian type c virus group-specific (gs) antigenic determinant, gs-3. the guinea pig antisera mainly contained species-specific (gs-1) antibody for reactions in gel diffusion with other type c viruses were limited to those of rat orig ... | 1972 | 4117346 |
in vitro transformation of canine embryo cells by murine sarcoma virus (kirsten). | 1973 | 4121083 | |
isolation of rd-114-like oncornavirus from a cat cell line. | a clone of cells derived from a continuous line of cat cells (ccc) spontaneously produced an rna c-type virus (ccc virus) which did not have the group-specific antigen of the standard strains of feline leukemia viruses but did have that of the rd-114 virus. single-hit infection of a virus yielding ccc cell with only the feline leukemia virus pseudotype of murine sarcoma virus [msv(felv)] resulted in the release of a pseudotype of msv coated with the ccc virus envelope. host range, transmission o ... | 1973 | 4123287 |
mutants of nonproducer cell lines transformed by murine sarcoma virus. ii. relationship of tumorigenicity to presence of viral markers and rescuable sarcoma genome. | tumorigenic and nontumorigenic mutants induced by a single 5'-bromodeoxyuridine (brdu) treatment of a nonproducer (np) tumorigenic cell line were isolated and characterized. among the cloned derivatives were examples of virus-free and sarcoma virus-producing cell lines. oncogenicity did not correlate with production of virus or ease of rescue of the sarcoma genome. all lines, including nononcogenic derivatives, retained the sarcoma genome. phenotypic reversion of some cell mutants was observed a ... | 1973 | 4124209 |
chemotherapeutic response of epithelial tumors produced by primary implantation of a nonproducer line of murine sarcoma virus-transformed balb 3t3 cells. | 1973 | 4126380 | |
revertants of mouse cells transformed by murine sarcoma virus. ii. flat variants induced by fluordeoxyuridine and colcemid. | 1973 | 4126841 | |
effects of polyadenylic acids on functions of murine rna tumor viruses. | single-stranded polyribonucleotides, which competitively inhibit murine rna tumor virus reverse transcriptase in vitro, were tested as inhibitors of various virus functions in cell culture. the compounds had two concentration-dependent effects. at high concentrations (100 mug/ml), both poly(adenylic acid) [poly(a)] and poly(2'-o-methyladenylic acid) [poly(am)] inhibited the uptake of radioactively labeled leukemia virus by swiss mouse embryo cells, but neither had a similar effect on sindbis vir ... | 1973 | 4128377 |
cell-mediated reaction against tumors induced by oncornaviruses. i. kinetics and specificity of the immune response in murine sarcoma virus (msv)-induced tumors and transplanted lymphomas. | 1972 | 4128690 | |
transformation assay for murine sarcoma viruses using a simian virus 40-transformed human cell line. | 1974 | 4129832 | |
specificity of the dna product of rna-dependent dna polymerase in type c viruses. ii. quantitative analysis. | a number of mammalian type c viruses were analyzed for relatedness by the technique of dna.rna hybridization. viral dnas were prepared in single-stranded form from complexes with 70s viral rna formed during endogenous polymerase reactions. extent of hybridization was assayed with the single-strand nuclease (s-1) from aspergillus oryzae. results obtained indicated a high degree of viral specificity, with significant cross-reactions being observed only with viruses obtained from within a species, ... | 1973 | 4129928 |
properties of 3t3 cells transformed by murine sarcoma virus in the absence of replicating murine leukemia helper virus. | 1973 | 4130395 | |
murine sarcoma virus-transformed nonproducer rat cell lines resistant to type c-virus infection. | 1973 | 4131817 | |
revertants of mouse cells transformed by murine sarcoma virus. 3. metastable expression of virus functions in revertants retransformed by murine sarcoma virus. | 1974 | 4133134 | |
antigens of tumours induced by naturally occurring murine sarcoma virus (msv-fbj). ii. detection of cell-surface antigens by indirect membrane immunofluorescence. | 1974 | 4133783 | |
in utero tumor induction by murine sarcoma virus (moloney) in the rat. ii. histological and ultrastructural characteristics. | 1973 | 4133944 | |
wide host range of murine sarcoma virus. | 1973 | 4134009 | |
expression of the defective "s plus l-" type murine sarcoma virus genome in human amnion and lung cells. | 1974 | 4134499 | |
separation of ribonuclease h and rna directed dna polymerase (reverse transcriptase) of murine type-c rna tumor viruses. | ribonuclease h (rna.dna-hybrid ribonucleotidohydrolase, ec 3.1.4.34) has been reported to copurify with reverse transcriptase (rna directed dna polymerase) of rna tumor viruses. in addition, viral specific ribonuclease h and reverse transcriptase of avian type-c viruses are thought to be part of the same polypeptide. in this report we show that a fraction of the ribonuclease h activity from rauscher murine leukemia and kirsten murine sarcoma viruses was separated from reverse transcriptase by an ... | 1974 | 4134616 |
baboon virus isolate m-7 with properties similar to feline virus rd-114. | a virus (m-7) isolated from baboon placental tissue demonstrates many similarities to endogenous feline virus rd-114. immunodiffusion analysis shows a group-specific antigen (gs-1) line of identity between m-7 and rd-114. anti-rd-114 dna polymerase igg inhibits m-7 polymerase by 57% compared to 97% for rd-114. m-7 virus has helper activity as demonstrated by rescue of murine sarcoma virus (msv) from sarcoma-positive leukemia-negative human amnion cells. the host range of the rescued m-7 pseudoty ... | 1974 | 4134740 |
viral rna of murine sarcoma virus produced by a hamster-mouse somatic cell hybrid. | 1974 | 4135225 | |
specificity of the dna product of rna-dependent dna polymerase in type c viruses: 3. analysis of viruses derived from syrian hamsters. | dna transcripts were prepared from three related viruses of hamster and analyzed by interviral hybridization and by reaction with cellular dna. a virus (g-halv), isolated from a dimethylbenzanthraceneinduced tumor cell in graffi hamsters, contained nucleic acid sequences highly specific for hamster cell dna and did not react with mouse cell dna nor did its transcript show homology (<5%) with mouse or rat viral rnas. the hamster-specific sarcoma virus, b-34, isolated by bassin and coworkers from ... | 1974 | 4137938 |
an immunoelectron microscopy study of soehner-dmochowski murine sarcoma virus following passage in rats and hamsters. | 1974 | 4138610 | |
specificity of 51cr-release cytotoxicity of lymphocytes immune to murine sarcoma virus. | 1974 | 4139276 | |
expression of the major internal viral polypeptide in cells transformed by wild-type and temperature-sensitive murine sarcoma virus. | phenotypic expression of the murine intraspecies and interspecies antigenic determinants of the major type c viral structural 30,000-dalton polypeptide, p30, was measured by radioimmunoassay inhibition in cell lines from different species. uninfected normal rat kidney (nrk) cells did not contain detectable levels of murine intraspecies and interspecies p30 antigen, whereas rat cells transformed by and producing murine sarcoma virus (msv)-moloney leukemia virus (m-msv-mulv) contained high levels ... | 1974 | 4139289 |
surface antigens of mammalian sarcoma virus-transformed nonproducer cells. | in vitro, clonal balb/3t3 mouse cells were transformed into nonproductive sarcoma cells by kirsten murine sarcoma virus. the resulting cells are called k-balb. similarly, the kirsten sarcoma virus and woolly monkey sarcoma virus transformed normal rat embryonic kidney (nrk) cells to nonproductive sarcoma cells k-nrk and w-nrk, respectively. the presence of sarcoma cell surface antigen (scsa) on these three different cell lines has been examined by immunoelectron microscopy using the rabbit anti- ... | 1974 | 4139711 |
revertants of mouse cells transformed by murine sarcoma virus: flat variants without a rescuable sarcoma virus from a clone of balb/3t3 transformed by kirsten msv. | 1974 | 4140213 | |
characterization of the major viral polypeptide in cells transformed by wild-type and temperature-sensitive murine sarcoma virus. | 1974 | 4141344 | |
[proceedings: small molecular weight rna from a murine oncornavius: 85 rna from murine sarcoma virus (msv-m-mlv)]. | 1974 | 4141442 | |
transformation of a cloned renal epithelial cell line by moloney murine sarcoma virus (m-msv). | 1970 | 4142389 | |
biologic studies on hamster tumors induced by the murine sarcoma virus (moloney). | 1969 | 4181060 | |
cytologic specificity of response to moloney murine sarcoma virus as evident in a transplantable epithelioid neoplasm of the rat. | 1970 | 4194654 | |
[influence of temperature on the structural 8s light rna present in murine sarcoma virus (moloney strain)]. | 1973 | 4206001 | |
[presence of 8s light rna in cells chronically infected by the murine sarcoma virus (moloney strain)]. | 1973 | 4206632 | |
studies on the enzymology of the rhabdomyosarcoma induced by the murine sarcoma virus (moloney). | 1970 | 4251322 | |
in vitro transformation of rat embryo cells by a murine sarcoma virus. | 1966 | 4287210 | |
transformation of hamster embryo cells in vitro by murine sarcoma virus (harvey). | 1967 | 4292480 | |
morphological transformation of mouse embryo cells in vitro by murine sarcoma virus (harvey). | 1967 | 4293376 | |
intracranial tumours in rats injected intracerebrally with murine sarcoma virus (msv), moloney's strain. preliminary report. | 1966 | 4293629 | |
[infection and transformation of mouse embryo cells due to harvey's murine sarcoma virus]. | 1966 | 4294868 | |
[ultrastructural studies of a murine sarcoma virus (msv)]. | 1967 | 4295344 | |
rescue of the defective murine sarcoma virus genome by radiation-induced leukemia virus from c57bl mice. | 1967 | 4295580 | |
characteristics of the in vitro assay of murine sarcoma virus (moloney) and virus-infected cells. | 1968 | 4296210 | |
murine sarcoma virus (harvey): characteristics of focus formation in mouse embryo cell cultures, and virus production by hamster tumor cells. | 1968 | 4296942 | |
tissue culture assay of helper activity of murine leukemia virus for murine sarcoma virus. | 1968 | 4298946 | |
focus formation by murine sarcoma virus: enhancement by deae-dextran. | 1968 | 4299388 | |
altered properties of fujinami-virus-infected duck cells and murine sarcoma virus-infected rat cells. | 1968 | 4300776 | |
enhancing effect of diethylaminoethyl-dextran on the focus-forming titer of a murine sarcoma virus (harvey strain). | 1968 | 4301509 | |
[cellular conversion induced in vitro by murine sarcoma virus (moloney strain). an analysis of dose-response curves]. | 1968 | 4302082 | |
the differential action of neonatal thymectomy in mice infected with murine sarcoma virus-harvey (msv-h). | 1968 | 4302084 | |
susceptibility of praomys (mastomys) natalensis to the murine sarcoma virus-harvey (msv-h). | 1968 | 4302086 | |
inhibitory effect of immune serum on carcinogenesis in mice neonatally infected with murine sarcoma virus (harvey). | 1968 | 4303534 | |
replication of murine sarcoma virus-harvey (msv-h) in tissue cultures of virus-induced sarcomas. | 1968 | 4304098 | |
the effect of interferon on focus formation and yield of murine sarcoma virus in vitro. | 1969 | 4304352 | |
enhancing effect of the murine sarcoma virus (msv) on the replication of the mouse hepatitis virus (mhv) in vitro. | 1969 | 4306053 | |
properties of clonal lines of murine sarcoma virus transformed balb-3t3 cells. | 1969 | 4306523 | |
different cell culture characteristics of two strains of murine sarcoma virus. | 1969 | 4306803 | |
[morphologic cell transformation and virus replication after in vitro infection of human cells with moloney strain murine sarcoma virus]. | 1969 | 4306856 | |
radiation leukemia virus: quantitative tissue culture assay. | radiation leukemia virus does not propagate in tissue cultures from either swiss or c57bl mouse embryos, but it does augment focus formation by the defective moloney leukemia pseudotype of murine sarcoma virus in swiss mouse cells and thus can be quantitatively assayed. | 1969 | 4306917 |
transformation of a mouse cell line by murine sarcoma virus (moloney). | 1968 | 4307755 | |
karyological analysis of mouse and rat embryo cells transformed by murine sarcoma virus (harvey). | 1969 | 4307792 | |
[study of the mechanism of loss of sensitivity to the protective action of exogenous interferon in cells infected by murine sarcoma virus]. | 1969 | 4308008 | |
immune complexes in mice infected neonatally with moloney leukaemogenic and murine sarcoma viruses. | 1969 | 4308421 | |
a quantitative study on transformation of hamster embryo cells in vitro by murine sarcoma viruses (harvey and moloney). | 1969 | 4310108 |