Publications
Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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radioiodide uptake in brain, csf, thyroid, and salivary glands of audiogenic seizure mice. | dba/2j (dba) mice are susceptible to audiogenic seizures (ass) in an age-dependent manner. anion transport as measured by radioiodide uptake was determined in thyroid gland, salivary gland, skeletal muscle, cerebral cortex, cerebellum, brainstem, and csf from these mice at various ages. anion transport was also determined in c57bl/6j(c57) mice, an as-resistant strain. in thyroid, dba mice had an enhanced ability to concentrate iodide at 21 days of age when they have maximal as susceptibility, as ... | 1984 | 6745222 |
argininosuccinic acid synthetase deficiency in a hamster cell line and its complementation of argininosuccinic aciduria human fibroblasts. | unlike normal human cells, cultured fibroblasts from patients with argininosuccinic aciduria cannot synthesize arginine from citrulline because they have a deficiency of argininosuccinic acid lyase (asl). we have found that v79, a chinese hamster cell line, cannot grow on citrulline. although these cells show a normal uptake of citrulline and have levels of asl comparable to a human cell line (hela) which can grow in citrulline-containing medium, v79 cells have less than 5% of the argininosuccin ... | 1980 | 6777600 |
intestinal microflora and aging: age-related change of enzymes in the liver and the small intestine of germ-free and conventional rats. | the activities of various enzymes involved in detoxication and carbohydrate metabolism in the liver and the gastrointestinal tract of germfree (gf) and conventional (cv) rats, 8 and 40 weeks' old, were measured in relationship to intestinal microflora and aging. in 8-week-old rats, the activities of nitroreductase (nr) and aniline hydroxylase (ah) in the liver, and of alkaline phosphatase (alp), maltase and lactase in the duodenum were higher in gf than in cv rats, but the activities of arginosu ... | 1981 | 6796785 |
comparison of argininosuccinate synthetase from young and old rat livers. | properties of argininosuccinate synthetases (ass), including immunological properties and heat stability, from young and old rats were quite similar. however the degradation rates of ass from young and old rats were found to be different as shown in the experiment using the double labeling technique. three forms of this enzyme from young and old rat livers were separated by deae-sephadex a-50 column chromatography, and they were called ass 1, 2 and 3 in order of elution. the degradation rate of ... | 1981 | 6798716 |
[final host specificity of sarcocystis species transmitted by dogs (authors's transl)]. | dogs and raccoons were fed muscle of various intermediate hosts that had been infected either naturally or artificially wit sarcocystis species transmitted from dogs. the muscle samples used for the experiments contained cysts of the following species: s. sp. of the donkey, s. bovicanis of cattle, s. ovicanis and s. sp. of sheep, s. suicanis of pigs, or s. capracanis and s. sp. of goats. in all trails, the dogs shed sporocysts of the sarcocystis species concerned after a typical prepatency. in t ... | 1981 | 6798774 |
monoclonal antibodies specific for cell culture mycoplasmas. | mycoplasma infection of cell cultures is still a major problem in some laboratories. although several methods can be used for their detection, identification is normally by serological procedures. as no commercial source for the necessary antibodies is available we have prepared monoclonal antibodies to the five mycoplasma species that account for the majority of cell culture infections. these antibodies have been characterized by the growth inhibition test (git), immunofluorescence, and enzyme ... | 1982 | 6811415 |
properties of an aldose reductase from pig lens. comparative studies of an aldehyde reductase from pig lens. | two monomeric nadph enzymes from pig lens, an aldehyde reductase and an aldose reductase, have been characterized. the aldose reductase is obtained in a pure form. the aldehyde reductase, usually called hexonate dehydrogenase, is the same protein as that was recently isolated from pig liver [branlant, g. and biellmann, j.f. (1980) eur. j. biochem. 105, 611-621]. the aldose reductase is shown to have a number of properties in common with the aldehyde reductase, namely its physico-chemical propert ... | 1982 | 6819141 |
pituitary and chorionic gonadotrophic control of ovarian function during early pregnancy in equids. | concentrations of fsh, lh, chorionic gonadotrophin (cg) and progesterone were measured during early pregnancy in mares and donkeys carrying normal intraspecies and transferred extraspecies conceptuses. a secondary rise in progesterone concentrations occurred in normal intraspecies horse and donkey pregnancy soon after the appearance of cg but fsh concentrations continued to fluctuate and were not influenced by cg production. in donkeys carrying transferred horse conceptuses fsh concentrations fe ... | 1982 | 6820064 |
differentiation of meat according to species by the electrophoretic separation of muscle lactate dehydrogenase and esterase isoenzymes and isoelectric focusing of soluble muscle proteins. | species identification of fresh meat can be readily achieved by serological techniques with the limitation that closely related species, such as sheep/goat, cattle/buffalo and horse/donkey, cannot be differentiated. we have examined electrophoretic techniques with particular reference to the identification of meat from closely related species. the results showed that beef and buffalo meat and meat from red and grey kangaroos could be clearly distinguished by isoelectric focusing on polyacrylamid ... | 1983 | 6838437 |
a biochemical comparison of the in vitro replication of a virulent and an avirulent strain of venezuelan encephalitis virus. | the virulent venezuelan equine encephalitis (vee) virus strain, trinidad donkey (trd) and its vaccine derivative strain tc-83, demonstrated biological and biochemical differences in their replication. these two viruses had similarly shaped growth curves; however, trd virus-infected cells produced significantly more infectious virus than did the tc-83 virus-infected cells during the very early period of the replication cycle. trd virus inhibited host cell protein synthesis in vero cells earlier t ... | 1983 | 6842187 |
molecular cytogenetics of the equidae. ii. purification and cytological localization of a (g + c)-rich satellite dna from equus hemionus onager and cross-species hybridization to e. asinus chromosomes. | a (g + c)-rich satellite dna component (p = 1.716 g/ml) has been fractionated from the total dna of the iranian subspecies of the asiatic wild ass, equus hemionus onager, by successive dactinomycin-cscl and netropsin sulfate-cscl isopycnic gradients. complementary 3h-rna (crna) transcribed from the satellite dna hybridized predominantly to the centromeric and telomeric constitutive heterochromatic regions of onager chromosomes. these studies have suggested that satellite dna's with similar seque ... | 1983 | 6851669 |
observations on fasciola hepatica in donkeys from morocco. | regular monthly examination of a total of 422 donkey livers revealed fasciola hepatica infection throughout most of the year, with an annual prevalence of 5.9% (range 0-20%). the monthly mean number of worms per animal varied from 0 to 6.4 (annual average 1.6). of the infected animals 40% had less than ten worms, 28% between ten and 40, 24% between 41 and 70, and 8% over 71. the maximum number of flukes recovered from a single animal was 87. there were two peaks of infection, one in july (from t ... | 1983 | 6882064 |
donkeys, carrots, and sticks. some approaches to employee motivation. | 2010 | 6900905 | |
the jawbone of an ass. | 1981 | 6910290 | |
patterns of vestibular and neck responses and their interaction: a comparison between cat cortical neurons and human psychophysics. | the present study provides evidence that during whole-body rotation and during isolated rotation of either the head or the trunk, essentially the same processing of labyrinthine and neck afferent inputs takes place in neurons of the cat's ass cortex and in humans who try to distinguish these stimulus conditions. this processing includes, among others (1) measurement of angular velocity and displacement during labyrinthine stimulation (whole-body rotation); (2) indication of trunk rotation as wel ... | 1981 | 6951443 |
immunological aspects of the endometrial cup reaction and the effect of xenogeneic pregnancy in horses and donkeys. | 1982 | 6962845 | |
maternal anti-fetal cytotoxic antibody responses of equids during pregnancy. | the maternal immunological response to the developing equine fetus was investigated in 69 pregnancies of various genotypes. in normal intraspecies horse pregnancy (n = 16), 94% of mares produced strong cytotoxic antibody responses to paternal histocompatibility antigens which were first detectable between 44 and 70 days after ovulation. in all other types of pregnancy examined (intraspecies donkey, n = 19; interspecies mule, n = 6; interspecies hinny, n = 2; extraspecies horse-in-donkey, n = 3; ... | 1982 | 6962872 |
identification of salmonella typhi in faecal specimens by an antiserum-agar method. | an antiserum-agar technique was evaluated as a method for detecting salmonella typhi in faeces. thirty-one laboratory strains of s. typhi produced immunoprecipitate haloes during overnight growth on ss agar and blood-agar-base infusion agar (bab) containing donkey antiserum to a vaccine strain of s. typhi. other salmonella species sharing o serogroup antigens with s. typhi also produced haloes when streaked in pure culture on ss-antiserum agar but not on bab-antiserum agar. one hundred and forty ... | 1980 | 6991704 |
comparative morphometry of the upper bronchial tree in six mammalian species. | the length, diameter, and angle of branching of all airways through the sixth level of branching below the trachea were measured on corrosion casts prepared from the lungs of two animals whose bronchial geometry has not previously been studied, namely the donkey and the rabbit. these measurements and morphometric data for the rat, hamster, dog, and human obtained from other sources were analyzed and compared. the case prepared from human lungs exhibited an airway geometry that was clearly distin ... | 1981 | 7013567 |
studies of glucose metabolism in rhesus monkeys after venezuelan equine encephalitis virus infection. | previous studies have demonstrated a diabetogenic effect of venezuelan equine encephalitis (vee) virus in hamsters. a preliminary study was conducted in which five 2- to 3-year-old rhesus monkeys were infected with the virulent trinidad donkey strain of vee virus and their carbohydrate metabolism was studied over 10 months. all animals developed mild clinical illness (rhinorrhea, cough, fever), were viremic, and developed antibodies. as compared with the results of preinoculation intravenous glu ... | 1980 | 7014785 |
clarification of the database concept. | our concern is that nursing databases be structured to improve the efficiency of decision-making in nursing. the selection of database management systems that are compatible with the computer resources in a majority of settings is important to methodology. to facilitate methodological development, we encourage the inclusion of information in the nursing literature that details the investments in personnel, equipment, and facilities required to develop computerized databases. in the current state ... | 1981 | 7015291 |
a critical efficacy test of cambendazole in equids: the use of the geometric means to assess efficacy. | the anthelmintic efficacy of a 44.5% paste formulation of cambendazole was evaluated in a critical trial performed on 5 horses and a donkey. a dosage of 20 mg/kg showed reduction of mean parasite burdens as follows: strongylinae greater than 99%; cyathostominae 94%; immature and adult oxyuris equi 89 and greater than 99%; probstmayria vivipara greater than 99% and habronema muscae 97%. parascaris equorum and anoplocephala perfoliata were present in small numbers in individual animals only, and w ... | 1980 | 7017145 |
characterization of antibodies to canine renal renin. studies of interspecies homology of renin using antibodies as probe. | antibodies raised to pure canine renal renin were used to probe homology of renin from other species. goat, rabbit, and mouse antibodies exhibited similar properties and were specific for renin as confirmed by immunodiffusion, immunoelectrophoresis, and selective inhibition of renin enzymatic activity. goat antibody also inhibited the enzymatic activities of rat, hog, and bovine renin. immunologic cross reactivity was further confirmed by direct binding and competition assays. goat anti-(canine ... | 1982 | 7040231 |
comparison of two recently published algorithms for assessing the probability of adverse drug reactions. | 1 a simple valid and reliable method for estimating the probability of adverse drug reactions (adverse drug reactions probability scale, aps) has been recently described (naranjo et al., 1981a). 2 the results using aps were compared to those obtained with another more detailed algorithm (adverse reactions scoring system, ass) described by kramer et al. (1979). 3 sixty-three randomly selected adverse drug reactions (adrs) were rated by two observers, using aps and ass one year apart. the cases we ... | 1982 | 7059419 |
a simple reverse-phase high pressure liquid chromatographic determination of conjugated bile acids in serum and bile using a novel radial compression separation system. | a new hplc method for analyzing conjugated bile acids in bile and especially in serum is presented. for separation of novel radial compression system with a 10-cm flexible-walled reverse phase column (rcm-100 module, waters ass.) packed with micro-bondapak c18 was used. without any laborious hydrolysis and derivatization steps, 10 conjugated bile acids are separated easily with a mobile phase of methanol/0.01 mol/1 kh2po4 (150:50, v/v; ph 6.0) in about 30 min, determined with a variable uv detec ... | 1982 | 7060274 |
[the sequence of hemoglobins from an asiatic wild ass and a mountain zebra]. | the hemoglobins from an asiatic wild ass (equus hemionus kulan) and a mountain zebra (equus zebra) were analysed and the complete primary structure of the alpha and beta chains are described. the wild ass globin was separated in two alpha chains (alpha i and alpha ii) and one beta-chain by means of chromatography on cm-cellulose in 8m urea buffer at ph 6.5. the wild ass globin shows polymorphism in the alpha-chain like the horse hemoglobin. under the same chromatographic conditions only one alph ... | 1982 | 7061044 |
fluorimetric determination of unsubstituted and 9(8)-o-acetylated sialic acids in erythrocyte membranes. | a method is described for all quantitative determination of free or glycosidically bound sialic acids with special reference to erythrocyte membranes. sialic acids, unsubstituted in their side chains, quantitatively yield formaldehyde after mild periodate oxidation (1 mm naio4, 15 min, 4 degrees c, in the dark). the formaldehyde is determined by the reaction with acetylacetone and ammonium acetate which leads to a sensitive fluorogen (f 410/510 nm). sialic acids o-acetylated at c-9 or c-8 are no ... | 1982 | 7076126 |
[experimental model with the additional source of endogenous serotonin]. | the only experimental approach to the increase in the body serotonin level is a pharmacological one that has a number of shortcomings. the authors suggest an experimental model with additional source of endogenous serotonin (ass-model) which occurs after embryonal gastrointestinal tract transplantation beneath the skin of adult syngeneic mice. the developing transplants showed significant amounts of serotonin and serotonin-producing enterochromaffin cells. the ass-model provides long-term and se ... | 1982 | 7093493 |
a note on the vertebral formula of the donkey. | 1982 | 7093650 | |
relationship of cortex and medulla in the adrenal gland of the donkey. | 1982 | 7100641 | |
[the primary structure of the hemoglobin from a white rhinoceros (ceratotherium simum, perissodactyla): beta 2 glu]. | the hemoglobin from a white rhinoceros (ceratotherium simum) was analysed and the complete primary structure of the alpha and beta chains is described. the globin chains were separated on cm-cellulose column in 8m urea buffer. the amino acid sequences were mainly determined by automatic degradation of tryptic peptides in the sequenator. the results show, that globin consists of one alpha- and several beta-chain types. the beta chains differ at position beta 62 where the amino acids threonine, se ... | 1982 | 7141412 |
[gangliosides of neural and extraneural tissues of various species of mammals]. | the ganglioside patterns of the forebrain, cerebellum and brain stem from horse, donkey, mule and goat have been determined by thin-layer chromatography. gm1, gd1a, gd1b and gt1b are the four major brain gangliosides. n-acetylneuraminic acid as the predominant sialic acid (congruent to 97%) and traces of n-glycolyneuraminic acid were found. the four above mentioned major gangliosides were also found in the forebrain, cerebellum and brain stem of adult rats. this pattern is not modified in rats u ... | 1982 | 7146593 |
a screening test to differentiate cattle meat from horse, donkey, kangaroo, pig and sheep meats. | 1982 | 7150136 | |
studies on the excretion of ascorbic acid 2-sulfate and total vitamin c into human urine after oral administration of ascorbic acid 2-sulfate. | the excretion of ass and total vitamin c into urine after oral administration of ass to humans was investigated. when 10 mmol of ass was administered to the subjects, the excretion of ass into urine continued for 60 hr in males and 48 hr in females. the average amount excreted per hour was less than 5 mg. these results differed from those for asa and dasa orally administered to humans. the determination of vitamin c after oral administration of ass to the subjects consisting of ten males and six ... | 1982 | 7161646 |
[pain and its management with drugs]. | there must be a differentiation between acute and chronic pain. while acute pain should be treated causally, this is usually no longer possible when pain has become chronic. it may even become so intense that a chronic pain patient can no longer live a productive life. the pain threshold is decreased by endogenous substances like prostaglandin e, but also kallekrein and bradykinin. hyperadrenergic stimuli can advance pain; for example, the so-called phantom-limb pain. also important within the b ... | 1982 | 7169835 |
pancreatic adenocarcinoma in a donkey. | 1982 | 7173147 | |
glycosylation patterns of the envelope glycoproteins of an equine-virulent venezuelan encephalitis virus and its vaccine derivative. | the equine-virulent venezuelan encephalitis virus, trinidad donkey (trd), was compared to its vaccine derivative, tc-83 virus, by examining the glycosylation of the two structural envelope glycoproteins (e1 and e2). the number of size classes of glycopeptides on the glycoproteins was determined by p-6 column chromatography following pronase digestion. the e1 glycoprotein had three glycopeptide size species and the e2 glycoprotein contained four size species ranging in mol. wt. from 1900 to 2700. ... | 1982 | 7175499 |
anthelmintic efficacy of fenbendazole in donkeys assessed by the modified non-parametric method. | 1982 | 7175906 | |
studies on strongylus asini. i. experimental infestation of equines. | infective larvae were harvested from a culture of eggs collected from adult strongylus asini recovered from a free-ranging burchell's zebra, equus burchelli, in the kruger national park. worm-free zebra, horse and donkey foals were successfully infested, but infestation failed in a mule foal. at slaughter, 117-125 days post-infestation, s. asini in their 4th moult were recovered from the liver and portal veins. this is the first report of successful experimental infestation of these hosts with s ... | 1982 | 7177594 |
field use of an acetylpromazine/methadone/ketamine combination for anaesthesia in the horse and donkey. | 1982 | 7179678 | |
administration of antisomatotropin serum in diabetes mellitus. | the effect of antisomatotropin serum (ass), raised in horse against human growth hormone, on the carbohydrate metabolism of diabetics has been investigated. among the eight diabetic patients treated so far two had gh secreting pituitary adenoma, two insulin-dependent, and four others adult onset diabetes mellitus. the glucose tolerance curve improved in all but one patient. the effect lasted for two--four weeks. because of this short time of efficiency, the place of ass in the definite treatmen ... | 1981 | 7227326 |
immunochemical determination of ldh-1. | an evaluation of a new immunochemical method for the heart isoenzyme of lactic dehydrogenase (ldh-1) is described. in this assay, a goat antibody against the m subunit of ldh is added to a patient's serum. donkey antigoat gamma globulin is then added, which precipitates the m-anti-m complex. ldh activity in the supernatant is thus a measure of the heart isoenzyme, since this isoenzyme is not precipitable by the anti-m antibody. assays for total ck, ck-mb, and total ldh, and ldh electrophoresis w ... | 1981 | 7234756 |
anthelmintic efficiency of fenbendazole in equines. | a single oral dose of fenbendazole (fbz) at 10mg/kg body mass was given to 5 donkeys. a further 5 donkeys were dosed with a medicated lick (1 mg fbz/g lick) until the oral consumption was 10mg/kg body mass. in both trials fbz was highly effective against adults of the following genera: cyathostomum, cylicocyelus, cylicostephanus, cylicodontophorus, poteriostomum, cabellonema, craterostomum and triodontophorus; similarly high efficiency was obtained against the following species: habronema majus, ... | 1980 | 7241490 |
sickled erythrocytes accelerate clotting in vitro: an effect of abnormal membrane lipid asymmetry. | a membrane lipid abnormality induced by sickling and found as a permanent alteration in the irreversibly sickled cell (isc) is the rearrangement of phosphatidyl ethanolamine (pe) and phosphatidyl serine (ps) from the inner to the exterior side of the lipid bilayer. since ps can provide a catalytic surface for the binding of blood coagulation factors and thus can exhibit procoagulant activity, we investigated the influence of oxy and deoxy reversibly sickled cells (rsc) ass well as isc on clottin ... | 1981 | 7248527 |
dietary and hormonal regulation of urea cycle enzymes in rat liver. | when 6-week-old rats fed normal diet (22% protein) were transferred to 10 and 75% protein diet, the levels of urea cycle enzymes showed decreases and increases respectively. the activities expressed as units per gram wet weight of liver had not stabilized after 7 days on the new diet; the corresponding specific activities were closer to leveling off. four daily injections of cortisol raised cps, ass, and arginase. the percentage increases were greater on a 10 than on a 75% protein diet. adrenale ... | 1981 | 7250092 |
[acetylsalicylic acid and food additive intolerance in urticaria, bronchial asthma and rhinopathy]. | adverse reactions (urticaria, angio-edema, bronchoconstriction, purpura) to aspirin (ass) and food-and-drug additives such as the yellow dye tartrazine and the preservative benzoate are observed all over the world. since the exact pathogenetic mechanisms of this condition is unknown, it is described as intolerance or pseudo-allergy and has been related to an imbalance of prostaglandin synthesis. among 620 patients with urticaria, bronchial asthma or chronic rhinitis, oral provocation tests with ... | 1981 | 7291963 |
a survey of schoolchildren from a severe endemic goitre area in spain. | all the boys and girls between six and fourteen years old regularly attending school in three villages from an area in spain known ass las hurdes were studied with respect to thyroid size, body weight and height. casual urine samples were obtained for the determination of iodine and creatine concentrations. capillary blood was spotted on filter paper and used for the determination of thyroxine and thyrotropin by radioimmunoassay. the same survey was carried out in 354 school children from madrid ... | 1981 | 7302120 |
vestibulo-thalamic projection to the anterior suprasylvian cortex of the cat. | suggestive evidence as to the site of a major thalamic relay of the vestibular projection to the anterior suprasylvian (ass) cortex in the cat has been obtained using the retrograde axonal transport of horseradish peroxidase. the thalamo-cortical neurons are located in several patches surrounding the posterior margins of the ventro-basal complex (vb). this area also was found to receive vestibulo-thalamic projections. it comprises different nuclear groups known to carry somatic, acoustic, visual ... | 1981 | 7308362 |
steatitis in two donkey foals. | 1981 | 7316897 | |
brain-stem responses when masking with wide-band and high-pass filtered noise. | investigations, using click stimuli masked by wide-band and high-pass filtered noise with cut-off frequencies of 2 600, 1 250 and 850 hz were carried out. the latency shift of a response evoked by a click of 60 db hl and wide-band masking at 80 db hl is 0.2 - 0.3 ms for wave i and about 0.6 ms for wave v. the results obtained with high-pass masking at various cut-off frequencies differ distinctly from those found by other authors. for instance, when using high-pass masking noise of a lower limit ... | 1981 | 7323676 |
trichophyton mentagrophytes infection in the domestic donkey (equus asinus asinus). | 1981 | 7325738 | |
[the genus onchocherca : hypothesis on its evolution and a key to the species (author's transl)]. | a phylogenetic tree and a dichotomic key to the species in the genus onchocerca are proposed. the origin and principal evolution have taken place in africa where the most primitive species (o. railieti in the donkey) and the greatest number of species (half of the 24 representatives of the genus) occur. this evolution apparently took place in a relatively recent geological period, corresponding perhaps to the establishment of the equidae in africa during the pleistocene. the species in humans, o ... | 1981 | 7332196 |
experimental transmission of echinococcus granulosus of "camel-dog" origin to goats, sheep, cattle and donkeys. | the infectivity of a camel strain of echinococcus granulosus experimentally raised in dogs for domesticated food and burden animals was investigated. of the animal species that were inoculated orally with gravid segments, hydatid cysts developed poorly in goats and sheep, less well in cattle and not at all in donkeys by six month post-inoculation. cysts were most frequently found in the lungs, although other organs such as liver and spleen also contained cysts. histological examination of affect ... | 1981 | 7333783 |
rabies in farm livestock in nigeria. | between 1944 and 1977, the distribution of confirmed cases of rabies in farm livestock in nigeria were 15 in cattle, 8 in goats, 4 each in sheep, pigs and horses and two in donkeys respectively. the less-cared-for pastoralist sheep - dogs as well as stray dogs have so far been the sole propagating animal species of rabies to farm livestock although wild fauna have been suspected. the fact that cases are sporadic and lower incidence of livestock rabies is generally reported than the number that a ... | 1981 | 7333785 |
studies of feral donkeys in the victoria river-kimberleys area. observations on behaviour, reproduction and habitat and some possible control strategies. | 1981 | 7337594 | |
genetic linkage between the ah locus and a major gene that inhibits susceptibility to audiogenic seizures in mice. | mice of the dba/2 (d2) strain are highly susceptible to sound-induced seizures at 21 days of age; whereas, mice of the c57bl/6 (b6) strain are resistant to these seizures. although the difference in susceptibility to audiogenic seizures (ass) between these two strains is inherited as a multiple-factor trait, an association was observed between susceptibility to ass and the ah locus. the ah locus controls the inducibility of aryl hydrocarbon hydroxylase (ahh) activity by a number of aromatic hydr ... | 1981 | 7341353 |
effects of sulfuric acid aerosol inhalations. | submicrometer h2so4 droplets can affect pulmonary functions in humans. the lowest concentration which has been reported to produce a statistically significant effect on pulmonary mechanics is 1 mg/m3. effects on tracheobronchial mucociliary clearance of inert particles were observed in our laboratory at much lower concentrations. for ten nonsmoking humans exposed for one hour via nasal mask to 0.1 mg/m3 of h2so4, the mean bronchial clearance half-time was reduced by 38% (p less than 0.02) while ... | 1980 | 7342776 |
remanent magnetic fields for measuring particle retention and distribution in the lungs. | a relatively inexpensive method for the noninvasive in vivo detection of ferrimagnetic particles within the lungs of a large laboratory animal, viz., the donkey, is described. the particles were neutron activated prior to inhalation, which permitted a comparison of two different retention measurements for the same particles, i.e., a well-characterized radiological-detection method concurrent with the newer magnetic-field technique. the long-term clearance of the particles from the lung was monit ... | 1981 | 7346267 |
ganglioside pattern and sialic acid content of horse, donkey, and mule brain. | 1980 | 7354347 | |
a short study of the seminal colliculus in some mammals. | the seminal colliculus is completely absent in the donkey. it is fibroglandular in the males of camel, ox, buffalo and pig. prostatic acini are richly found in its depth. they are lined by cubical or low columnar epithelium, are separated from each other by trabeculae of connective tissue and smooth muscle, and separated from the deeper prostrate gland by the striated muscle of the urethra. a rare type of seminal colliculus was once encountered in the ox. this type is muscular with autonomic gan ... | 1980 | 7386162 |
genetic analysis of audiogenic seizure susceptibility in c57bl/6j x dba/2j recombinant inbred strains of mice. | the inheritance of susceptibility to audiogenic seizures (ass) was studied in the c57bl/6j (b6) and dba/2j (d2) progenitor strains, their reciprocal f(1) hybrids, backcross generations and in 21 b6 x d2 recombinant inbred (ri) strains of mice at 21 days of age. all of the d2 mice tested experienced ass, whereas none of the b6 mice responded to the sound. although 23% of the f(1) mice experienced wild running, they were generally as resistant to ass as their b6 parents. mice of the f(1)x b6 backc ... | 1980 | 7399258 |
hunger vs thirst in the burro (equus asinus). | 1980 | 7403300 | |
a novel synergistic effect of alanosine and guanine on adenine nucleotide synthesis in mammalian cells. alanosine as a useful probe for investigating purine nucleotide metabolism. | a novel synergistic effect of the antitumor agent alanosine (2-amino-3-(hydroxynitrosoamino) propionic acid), which specifically inhibits the enzyme adenylosuccinate synthetase (ass) and guanine on the growth of chinese hamster ovary (cho) cells and human diploid fibroblasts (hdf) has been observed. in the presence of subinhibitory concentrations of alanosine, both cho cells and the hdf show excessive sensitivity to exogenous guanine--a phenotype which closely resembles that seen with some of th ... | 1980 | 7410492 |
purification and characterization of donkey chorionic gonadotrophin. | serum of the pregnant donkey, like that of the mare, contains a gonadotrophin of chorionic origin. the chorionic gonaditrophin of the donkey (dcg) has been isolated in purified form from the serum of pregnant donkeys using methodology previously employed for the purification of pregnant mare chorionic gonadotrophin (ecg). unlike ecg, dcg is predominatly an lh in biological tests. in the in-vitro rat leydig cell assay, dcg was as active as ecg, but in the in-vitro rat seminiferous tubule assay fo ... | 1980 | 7411010 |
variation of acidic prealbumins in the donkey (equus asinus). | starch gel electrophoresis of 55 donkey serum samples revealed three prealbumin (pr) phenotypes temporarily designated pr m, pr mt and pr t. the distribution was in agreement with a genetic theory of two codominant alleles of frequencies, prm = 0.87 and prt - 0.13. variation was also observed for proteins migrating with the same rate as the xh zones in the horse. | 1980 | 7436051 |
pneumonia in a donkey. | 1980 | 7445355 | |
gastrointestinal osmolality electrolyte and organic acid composition in five species of east african herbivorous mammals. | inherent differences observed in ionic composition of gastrointestinal contents due to diet, feeding regimen and (or) site along the length of the digestive tract were controlled so that a clearer understanding of species differences could be obtained. three species of ruminants (i.e., zebu cattle, sheep and goat), a pseudo-ruminant (camel) and a nonruminant (donkey) were compared. specific differences were observed in organic acid concentration, ph and electrolyte composition at various sites a ... | 1980 | 7462117 |
hydatidosis in donkeys in morocco. | 1980 | 7469567 | |
[jackson's sarcoid: the 1st description of a case observed in tunisia]. | the first description of sarcoid of jackson observed in tunisia in an adult donkey permit to the authors to give a light to the possibilities of its experimental transmission. | 1980 | 7469616 |
the nucleotide sequence of asinine herpesvirus 3 glycoprotein g indicates that the donkey virus is closely related to equine herpesvirus 1. | the nucleotide sequence of the glycoprotein g (gg) homologue of asinine herpesvirus 3 (ahv3), a respiratory alphaherpesvirus of donkeys, was determined. the ahv3 gg gene consists of 1233 base pairs (bp) and codes for a predicted protein of 411 amino acids. this is identical in size to the equine herpesvirus 1 (ehv1) gg gene and 6 amino acids longer than the equine herpesvirus 4 (ehv4) gg gene. the predicted amino acid sequence of ahv3 gg has characteristics of a class 1 membrane protein. the ami ... | 1995 | 7487497 |
localization of four antigenic sites involved in venezuelan equine encephalomyelitis virus protection. | stable neutralization and protection escape variants of a virulent strain (trinidad donkey) of the vee virus were selected by monoclonal antibodies (mabs). determination of nucleotide sequences of nine variants revealed a clustering of single mutations in four regions of the e1 and e2 glycoproteins. involvement of amino acid residues 206 (site e1-1), 57 and 59 (site e2-2), 180, 182, 213, 214 and 216 (site e2-6) and 232 (site e2-3) in protective epitopes was demonstrated. | 1994 | 7529989 |
diffuse large cell lymphomas exhibit frequent deletions in 9p21-22 and 9q31-34 regions. | we have previously identified deletions of 9p and 9q in a cytogenetic analysis of a large series of non-hodgkin's lymphomas (nhls), which suggested loss of candidate tumor suppressor genes (tsgs). in order to define these deletions at the molecular level, we performed an loh analysis of a panel of paired normal and tumor dnas comprising 13 cases of diffuse lymphoma with a large cell component (dllc) and 18 cases of burkitt's lymphoma (bl). the loci tested comprised eight polymorphic probes mappe ... | 1995 | 7534108 |
localization of a protective epitope on a venezuelan equine encephalomyelitis (vee) virus peptide that protects mice from both epizootic and enzootic vee virus challenge and is immunogenic in horses. | in order to define more precisely the protective epitope encoded within the first 25 amino acids (aa) of the e2 glycoprotein of the trinidad donkey strain of venezuelan equine encephalomyelitis (vee) virus, we examined the immunogenicity of smaller peptides within the first 19 aa. pep1-9 and pep3-10 elicited virus-reactive antibody, but failed to protect mice from virus challenge. additionally, pep3-10 was identified by a competitive binding assay using overlapping peptide octamers as the putati ... | 1995 | 7543231 |
caloric intake stimulates growth hormone secretion in food-deprived rats with anterolateral deafferentation of the medial basal hypothalamus or administered antiserum to somatostatin. | in rats, food deprivation inhibits episodic growth hormone (gh) secretion. on the basis of previous studies, we hypothesized that during a recovery from prolonged fasting, caloric intake stimulates the release of gh-releasing factor (grf) and this process does not depend on the specific macronutrients in the meal, while protein in the meal acts to restore characteristic ultradian rhythmicity of gh secretion. to test this hypothesis, the effect of caloric intake on gh secretion was examined in fa ... | 1995 | 7550296 |
disposition of penicillin g sodium following intravenous and oral administration to equidae. | the present study was designed to determine and compare the plasma disposition and pharmacokinetics of penicillin g sodium following intravenous (i.v.) administration to horses, ponies and donkeys. the plasma disposition and pharmacokinetics of penicillin g was similar in horses, ponies and donkeys (elimination half-lives--39.0, 27.3 and 31.5 min, respectively) and a dosage interval of 6-8 h would be suitable to treat infections caused by susceptible bacteria. although penicillin g was absorbed ... | 1995 | 7552196 |
pancreatic secretory trypsin inhibitor gene is highly expressed in the liver of adult-onset type ii citrullinemia. | deficiency of argininosuccinate synthetase (ass) causes citrullinemia. type ii citrullinemia is found in most patients with adult-onset citrullinemia in japan, and ass is deficient specifically in the liver. previous studies have shown that the decrease of hepatic ass activity is caused by a decrease in enzyme protein with normal kinetic properties and that there are no apparent abnormalities in the amount, translational activity, and nucleotide sequence of hepatic ass mrna. recent results of ho ... | 1995 | 7556646 |
nature and frequency of mutations in the argininosuccinate synthetase gene that cause classical citrullinemia. | citrullinemia is an autosomal recessive disorder caused by a genetic deficiency of argininosuccinate synthetase (ass). so far 20 mutations in ass mrna have been identified in human classical citrullinemia, including 14 single base changes causing missense mutations in the coding sequence of the enzyme, 4 mutations associated with an absence of exons 5, 6, 7, or 13 in mrna, 1 mutation with a deletion of the first 7 bases in exon 16 (which is caused by abnormal splicing), and 1 mutation with an in ... | 1995 | 7557970 |
continuing prevalence of african horse sickness in nigeria. | equine sera collected from 10 widely separated regions throughout nigeria were tested for antibodies against african horse sickness viruses (ahsv) using a competitive enzyme-linked immunosorbent assay (elisa). the animals sampled included imported, exotic horses, indigenous and locally cross-bred (local) horses and african donkeys. a high percentage of the sera (79.8%) were positive, confirming the continued prevalence of ahsv antibodies in nigerian horses and donkeys. | 1995 | 7569227 |
donkey klossiellosis in kenya. | out of eight donkeys examined, two had gametogonic and sporogonic stages of klossiella equi in their kidneys. gametogonic stages included microgametocytes and macrogametocytes, some of them in syzygy. they were found in enlarged parasitophorous vacuoles situated in epithelial cells of the renal tubules. sporonts were seen in the epithelial cells protruding into the tubular lumen while sporoblasts, sporocysts and sporozoites were found freely in the tubular lumen. entire sporocysts were rarely en ... | 1995 | 7571332 |
assumed oxygen consumption based on calculation from dye dilution cardiac output: an improved formula. | this study was performed because of observed differences between dye dilution cardiac output and the fick cardiac output, calculated from estimated oxygen consumption according to lafarge and miettinen, and to find a better formula for assumed oxygen consumption. in 250 patients who underwent left and right heart catheterization, the oxygen consumption vo2 (ml.min-1) was calculated using fick's principle. either pulmonary or systemic flow, as measured by dye dilution, was used in combination wit ... | 1995 | 7588904 |
proteolytic cleavage of vp2, an outer capsid protein of african horse sickness virus, by species-specific serum proteases enhances infectivity in culicoides. | purified african horse sickness virus (ahsv) was fed, as part of a blood meal, to adult females from a susceptible colony of culicoides variipennis, established in the insectories at the institute for animal health, pirbright laboratory, uk. the meal consisted of heparinized blood obtained from ovine, bovine, equine (horse and donkey) or canine sources spiked with ahsv serotype 9 (ahsv9). the infectivity levels observed for c. variipennis varied significantly, according to the source of the bloo ... | 1995 | 7595366 |
an investigation into the potential veterinary needs of a semi-rural low-income community. | the diagnostic phase of an interactive veterinary research evaluation model was used in the investigation into the potential veterinary needs of a low-income, semi-rural community. the economic status of households was estimated according to an economic situation score (esscore) and a subjective nutritional score (sns). data were gathered by means of structured interviews and direct observations. sixty-one per cent of the households (n = 190) owned animals. dogs were the animal most frequently o ... | 1994 | 7595924 |
animal traction in south africa: research priorities in veterinary science. | during june 1994, members of numerous organisations with a vested interest in animal traction in south africa met for a one-day workshop, the initial activity of a forum on working animals. the workshop was sponsored by the foundation for research development in south africa. the individuals who attended were representatives of academic and government institutions, farmer and civic organisations, and included veterinarians and veterinary scientists, administrators, traction experts from the regi ... | 1994 | 7602567 |
wesselsbron virus antibody in domestic animals in nigeria: retrospective and prospective studies. | retrospective and prospective serological surveys to determine the prevalence of wesslsbron (wsl) virus infections in animal populations were carried out in different vegetational zones in nigeria. sera from 1,492 animals comprising 292 camels, 81 horses, 4 donkeys, 320 cattle, 235 sheep, 260 goats, 114 pigs, 101 dogs and 85 domestic fowls were assayed by haemagglutination-inhibition (hi) test for presence of antibodies to wsl virus and other flavivirus antigens: yellow fever (yf), potiskum (pot ... | 1995 | 7603342 |
[saccharomyces cerevisiae ade12 gene, coding for adenylosuccinate synthetase (ec 6.3.4.4). cloning, sequencing, expression, and superproduction]. | the cloning and sequencing of saccharomyces cerevisiae ade12 gene encoding the structure of adenylsuccinate synthetase (ass) are reported for the first time. comparative analysis of all known ass sequences was carried out. regulation of ade12 gene expression by exogenic adenine was carried out. the properties of ass which was isolated and purified from overproducing yeast strain were examined. | 1995 | 7603488 |
bloodfeeding behavior of anopheles sacharovi in turkey. | the feeding habits of anopheles sacharovi under natural conditions and in feeding rooms were investigated by use of the gel diffusion technique. mosquitoes were collected from various villages of cukurova and also from feeding rooms especially prepared for these experiments. human, cow, sheep, chicken, horse, and donkey were used as hosts in these rooms. the results showed that an. sacharovi is a zoophilic species. the females preferred donkey when human, cow, sheep, chicken, and horse were equa ... | 1995 | 7616176 |
[prevention of reinfarction with 100 mg or 30 mg ass daily?]. | the prevention of heart infarction with 100 mg aspirin is common practice in germany, in spite of the fact that it is based on only two small studies, the results of which are not generalized. over 14 years, several experimental and clinical studies have shown that 20-30 mg aspirin/d for pharmacokinetic reason selectively inhibit the thromboxane synthesis while the endogenous prostacyclin synthesis remains intact. prostacyclin plays an important cardioprotective role for the ischemic heart, havi ... | 1995 | 7625094 |
intravenous disposition kinetics, oral and intramuscular bioavailability and urinary excretion of norfloxacin nicotinate in donkeys. | an aqueous solution of norfloxacin nicotinate (nfn) was administered to donkeys (aquus asinus) intravenously (once at 10 mg/kg), intramuscularly and orally (both routes once at 10 and 20 mg/kg, and for 5 days at 20 mg/kg/day). blood samples were collected at predetermined times after each treatment and urine was sampled after intravenous drug administration. serum nfn concentrations were determined by microbiological assay. intravenous injection of nfn over 45-60 s resulted in seizures, profuse ... | 1995 | 7629923 |
seroepidemiological and molecular evidence for the presence of two h3n8 equine influenza viruses in china in 1993-94. | in may 1993, a severe epidemic of respiratory disease began in horses in inner mongolia and spread throughout horses in china. the disease affected mules and donkeys as well as horses but did not spread to other species, including humans. the severity of the disease raised the question of whether the outbreak might have been caused by the new avian-like influenza viruses detected in horses in china in 1989 or by current variants ofa/equine/miami/1/63 (h3n8) (equine-2) or by a reassortant between ... | 1995 | 7636481 |
tapeworm infection in donkeys. | 1995 | 7638940 | |
cloning and analysis of the cdna encoding the horse and donkey luteinizing hormone beta-subunits. | the coding regions of the horse (equus caballus) and donkey (e. asinus) luteinizing hormone (lh) beta-subunit transcripts were cloned from pituitary gland rna, in order to investigate their relationships to the corresponding equine chorionic gonadotropin (cg) beta-subunits and to further understand the unusual receptor-binding properties of equine lh and cg. the horse and donkey lh beta-subunit sequences were very similar (97% identity at the nucleotide (nt) level; 93% at the amino acid (aa) lev ... | 1995 | 7642105 |
antegrade scrotal sclerotherapy for the treatment of varicocele in childhood and adolescence. | to test the efficacy of antegrade scrotal sclerotherapy (ass) for the treatment of varicocele in teenagers. | 1995 | 7648061 |
hyperlipidemia, hyperlipemia, and hepatic lipidosis in american miniature horses: 23 cases (1990-1994). | the medical records of 23 american miniature horses with hyperlipidemia, hyperlipemia, or hepatic lipidosis were reviewed. the most common clinical signs were anorexia and lethargy. the mean duration of clinical signs was 2.4 days. a primary disease was identified in 19 cases. enterocolitis was the most common primary disease (n = 10). intentional feed restriction, as part of treatment for colic, resulted in hyperlipemia in 2 horses and hyperlipidemia in 1. four horses had primary hyperlipemia, ... | 1995 | 7649775 |
[thrombocyte function of healthy probands taking 50 mg of acetylsalicylic acid per day]. | the antithrombotic effect of acetylsalicylic acid (ass) is attributed in part to its inhibitory action on platelet cyclooxygenase and, thereby, thromboxane a2 (txa2) formation. the therapeutic goal of low-dose ass regimens was the development of a preparation showing a high inhibitory capacity on platelet txa2 generation whilst leaving vascular prostaglandin i2 (pgi2) synthesis unaffected, thereby minimizing side effects. the effect of a new acid-resistant preparation of 50 mg ass (thrombo-ass 5 ... | 1995 | 7676685 |
attenuation of venezuelan equine encephalitis virus strain tc-83 is encoded by the 5'-noncoding region and the e2 envelope glycoprotein. | the virulent trinidad donkey (trd) strain of venezuelan equine encephalitis (vee) virus and its live attenuated vaccine derivative, tc-83 virus, have different neurovirulence characteristics. a full-length cdna clone of the tc-83 virus genome was constructed behind the bacteriophage t7 promoter in the polylinker of plasmid puc18. to identify the genomic determinants of tc-83 virus attenuation, trd virus-specific sequences were inserted into the tc-83 virus clone by in vitro mutagenesis or recomb ... | 1993 | 7679745 |
neuronal responses to vestibular and callosal stimulation in the anterior suprasylvian gyrus of the cat. | neuronal responses to electrical stimulation at the horizontal ampulla (ha), vestibular nerve (at the windows) and corpus callosum (cc) were investigated in neurons in the anterior suprasylvian gyrus of the cat. the field potentials to ha stimulation had short latency: 2.9 +/- 0.3 (mean +/- sd) ms from the stimulus to the onset and 5.6 +/- 1.9 ms to the peak. the focus of the evoked potentials was located in the anterior suprasylvian (ass) gyrus or near the ass sulcus. ha stimulation activated 6 ... | 1993 | 7683394 |
[serum argininosuccinate synthetase (ass) in patients with chronic hepatitis c treated with interferon]. | serum ass and serum gpt levels were determined in 16 patients with chronic hepatitis c treated with interferon. in all the patients, the serum ass level decreased earlier than the serum gpt level, and this tendency was remarkable in patients who excellently responded to the treatment. furthermore, the serum ass level was fluctuated when the serum gpt levels being continuously flat in the course of the treatment, probably because of the shorter half life of ass in the serum. in conclusion, the se ... | 1993 | 7685731 |
kinetics of interaction of hiv reverse transcriptase with primer/template. | intrinsic protein fluorescence of reverse transcriptases from hiv-1 and hiv-2 provides a sensitive signal for monitoring the interaction of the enzymes with primer/template duplex molecules. kd values for 18/36-mer dna/dna duplexes were found to be in the range of a few nanomolar (about 3 times higher for the enzyme from hiv-2 than for that from hiv-1). the quenching of protein fluorescence induced on binding primer/template, together with an increase in extrinsic fluorescence on interaction wit ... | 1993 | 7688571 |
[anesthetic management for a patient with citrullinemia and liver cirrhosis]. | we successfully anesthetized a 53-year-old female with hypercitrullinemia and severe liver cirrhosis. the hypercitrullinemia was accompanied with chronic hepatic encephalopathy due to hyperammonemia, which resulted from decreased activity of one of the urea cycle enzymes, argininosuccinate synthetase (ass). she was scheduled for replacement arthroplasty of a fractured femoral neck. she suffered a consciousness disturbance due to hyperammonemia, which was successfully treated by oral administrati ... | 1995 | 7699832 |
features of the dna fingerprinting probe pitz1. | stringently controlled plasmids generate dna fingerprint patterns in mammals when used at low hybridization temperatures. in order to develop a probe for use in paternity testing in cattle we screened a bovine, partial genomic plasmid library with the pcr-amplified ori region of plasmid p1. of eight isolated clones one generated strong band patterns at high stringency in various mammalian species (data not shown). sequence analysis revealed an imperfect, compound dinucleotide repeat region, whic ... | 1995 | 7702209 |