Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| mechanism of allergic cross-reactions. v. high incidence of unanticipated cross-stimulation by natural allergens of rat basophilic leukemia cells sensitized with monoclonal ige antibodies. | the incidence of cross-stimulations by natural allergens was investigated using rbl-2h3 cells sensitized with five different mouse monoclonal anti-dnp iges and four mercury-induced rat monoclonal iges. cells sensitized with 3 of the 5 monoclonal anti-dnp iges (clones spe-7, srt-1, lb4) responded by serotonin release upon stimulation by natural allergens such as dermatophagoides pteronyssinus, horse dander and mugwort extracts. serotonin release could be inhibited by monovalent dnp-lysine, indica ... | 1995 | 7549509 |
| effect of diuretics on allergen-induced contractions of passively sensitized human bronchi in vitro. | inhaled furosemide has been shown to protect subjects with asthma from bronchoconstriction induced by a wide variety of stimuli, including allergen, but the mechanism of action is controversial. we have used an in vitro model of allergen-induced bronchoconstriction to examine the effects of furosemide and other ion transport inhibitors. human bronchial rings were passively sensitized by incubation with serum from an atopic donor and were challenged with dermatophagoides pteronyssinus. allergen-c ... | 1995 | 7551365 |
| [skin tests for different species of acari in asthmatic children from mexico city]. | house dust mites, dermatophagoides pteronyssinus (dp) and dermatophagoides farinae (df) are the predominant cause of allergic asthma in our population. to detect the presence of sensitivity to other mites besides dp and df in 100 children that live in mexico city, skin tests were performed in their arms with multi-test devices and glycerinated extracts. there were 34 female and 66 male, aged 4 to 14 years (x = 9.1y), with history of mild and moderate asthma, 2 months to 12 years of evolution. dp ... | 1995 | 7552183 |
| [frequency of allergens in immediate, late, and dual allergic skin response at the national institute of pediatrics]. | we studied 126 children with allergic illness in instituto nacional de pediatria. we applied cutaneous test to determine the early, late and dual response. the results were 68% for the early response, 6% late response and 26% dual response. the allergens more frequently found in the early and late response were dermatophagoides pteronyssinus, dermatophagoides farinae and house dust. approximately the third part of the children studied presented late cutaneous response (dual response more isolate ... | 1995 | 7552188 |
| specific down-regulation of anti-allergen ige and igg antibodies in humans associated with injections of allergen-specific antibody complexes. | several approaches have recently been put forward describing attempts to suppress the ige immune response towards allergens, which is thought to be the key event in allergic diseases. in a series of clinical trials we have shown that injections of complexes made up from allergen and specific antibodies are an effective treatment for allergic bronchial asthma and atopic dermatitis. in the work presented here we have examined the humoral immunity changes associated with the use of such complexes i ... | 1995 | 7553070 |
| no relationship between skin-infiltrating th2-like cells and allergen-specific ige response in atopic dermatitis. | more than 500 cd4+ t-cell clones (tccs) derived from the skin of eight patients with atopic dermatitis (ad), two patients with nonatopic dermatologic disorders, two patients with allergic rhinitis, and one healthy nonatopic donor were analyzed for both their pattern of cytokine production and their antigen specificity. the proportions of tccs from patients with ad producing interleukin-4 in response to stimulation with phorbol 12-myristate 13-acetate plus anti-cd3 antibody were higher, whereas t ... | 1995 | 7560644 |
| [prevalence of sensitization to blomia in gran canaria]. | in the present study we assessed the prevalence of sensitizations to blomia in our environment. perennial climatological conditions in the canarian islands facilitates the habitat to mites. the blomia is found in tropical and subtropical homes of europe, usa and asia like the dermatophagoides. we have designed a transversal and prospective study on 100 patients who consulted our unit for the first time. a prick-test for the common allergens, including blomia kulagini, and in vitro determination ... | 1995 | 7572538 |
| effects of "systemic" budesonide concentrations on in vitro allergen-induced activation of blood mononuclear cells isolated from asthmatic patients. | blood levels of inhaled corticosteroids are significantly lower than those measured in the lung, but their concentration could still have anti-inflammatory effects. to determine whether budesonide, at concentrations similar to those obtained in blood after drug inhalation (10(-9) m), could downregulate the allergen-induced activation of mononuclear cells, we studied 21 atopic patients, sensitized to dermatophagoides pteronyssinus (der p). on blood mononuclear cells, isolated from these patients, ... | 1995 | 7573828 |
| vineyard snail allergy possibly induced by sensitization to house-dust mite (dermatophagoides pteronyssinus). | a female patient experienced a severe allergic reaction after consumption of vineyard snails. the patient proved to be sensitized to house-dust mite (hdm) and demonstrated a positive skin test and specific ige to snail (eobania vermiculata, lofarma). the snail rast was > 80% inhibited by hdm, whereas the mite rast was < 10% inhibited by snail extract. this is possibly another example of food allergy related to primary sensitization by an aeroallergen. | 1995 | 7573833 |
| quantitation of major allergens in dust samples from urban populations collected in different seasons in two climatic areas of the basque region (spain). | we present the results of allergen content evaluation in 80 dust samples from 31 homes of atopic patients from two climatic areas (humid and subhumid), collected in two seasons of the year (autumn and winter). monoclonal antibody-based immunoassays were used to quantify der p 1, der f 1, der 2, lep d 1, and fel d 1. the results were compared according to climate, season, and the type of sensitization (pyroglyphidae mites, storage mites, or grass pollens). we underline the predominance of dermato ... | 1995 | 7573840 |
| platelet aggregation in ige-mediated allergy with elevated soluble fc epsilon rii/cd23 level. | in 25 house dust mite-sensitive patients with perennial allergic rhinitis, an analysis of platelet aggregation tests (dual-channel aggregometer, chronolog corp, 345 model) induced by adenosine diphosphate (adp) was carried out. the levels of total serum ige specific antibodies against dermatophagoides pteronyssinus and the soluble form of the low affinity ige receptor (sfc epsilon rii/scd23) were estimated as well. the study was carried out in a dynamic state, before and after 2 years of treatme ... | 2013 | 7582163 |
| effect of an asthmatic attack on cd23 and cd21 expression on lymphocytes from allergic children during the allergen season. | the overproduction of ige antibodies by atopic individuals in response to inhaled aeroallergen, forms the basis of an allergic disease. furthermore, the exposure to allergen might trigger the symptom exacerbation. | 1995 | 7584679 |
| polyinosinic acid: polycytidylic acid promotes t helper type 1-specific immune responses by stimulating macrophage production of interferon-alpha and interleukin-12. | the effects exerted on the development in vitro of dermatophagoides pteronyssinus group i (der p i)-specific t cell lines and t cell clones by addition of polyinosinic acid: polycytidylic acid (poly i:c) in lymphocyte bulk culture were examined. der p i-specific t cell lines generated in presence of poly i:c exhibited reduced ability to produce interleukin (il)-4 and il-5 and developed into der p i-specific cd4+ t cell clones showing a t helper (th) type 0 or th1, instead of th0/th2 cytokine pro ... | 1995 | 7589141 |
| peptide-induced anergy in allergen-specific human th2 cells results in lack of cytokine production and b cell help for ige synthesis. reversal by il-2, not by il-4 or il-13. | the induction of anergy in t cells is believed to be the result of triggering of the tcr in the absence of adequate costimulation mediated through the interaction of cd28 and its ligands, cd80 and cd86. here, we demonstrate that stimulation of human group i allergen in dermatophagoides pteronyssinus extract (der p 1)-specific cd4+ th2-like t cell clones with der p 1-derived peptides in the absence of professional apc results in a state of nonresponsiveness. the induction of anergy occurred despi ... | 1995 | 7594575 |
| a major house dust mite allergen disrupts the immunoglobulin e network by selectively cleaving cd23: innate protection by antiproteases. | asthma is a chronic life-threatening disease of worldwide importance. although allergic asthma and related atopic conditions correlate strongly with immune sensitization to house dust mites, it is unclear why antigens from mites provoke such powerful allergic immune responses. we have characterized the protease activity of der p i, the group i protease allergen of the house dust mite dermatophagoides pteronyssinus, and here report that it cleaves the low-affinity immunoglobulin (ig) e fc recepto ... | 1995 | 7595223 |
| lack of association between hla-dq and -dr genotypes and asthma in southern chinese patients. | asthma is an inflammatory disease with a strong genetic predisposition. we have studied a group of unrelated asthmatic patients of southern chinese origin on their hla-dr and -dq regions using molecular techniques and compared them with 104 healthy controls of the same ethnic origin. restriction fragment length polymorphism (rflp) was used to genotype the mhc class ii dr beta, dq alpha and dq beta loci of the subjects. polymerase chain reaction (pcr) using sequence specific primer (ssp) for dq b ... | 1995 | 7600378 |
| four species of house dust mites recovered from houses of patients with allergic respiratory diseases. | arthropods and their products are wide spread and considered one of the common allergens affecting man. allergy to arthropod antigens is the major cause of respiratory allergy as rhinitis and bronchial asthma. the range of reaction depends on several factors which include the type and source of the material, the rate of intensity, the duration of exposure, the human immune response and history of prior exposure. successful management of allergic disease depends on proper identification of the ca ... | 1995 | 7602163 |
| human ige in severe combined immunodeficiency mice reconstituted with peripheral blood mononuclear cells from dermatophagoides pteronyssinus-sensitive patients. | we studied conditions of human ige formation in severe combined immunodeficiency (scid) mice engrafted with peripheral blood mononuclear cells (pbmcs) from allergic patients sensitive to dermatophagoides pteronyssinus (d.pt.). with 10 x 10(6) pbmcs injected intraperitoneally, the hu-scid mice developed an ige response, but only if experimental animals were immunized with the related allergen. two routes of immunization were tested: intraperitoneal and inhalation. in these experimental conditions ... | 1995 | 7613137 |
| evaluation of the inhibitory effects of budesonide on the mitogen-induced or the allergen-induced activation of blood mononuclear cells isolated from asthmatic patients. | corticosteroids are thought to be effective in the treatment of allergic reactions including bronchial asthma because they not only have anti-inflammatory effects, but also downregulate the processes of t-cell activation. | 1995 | 7621058 |
| immunochemical characterization of recombinant and native tropomyosins as a new allergen from the house dust mite, dermatophagoides farinae. | two predominant mite species, dermatophagoides farinae and dermatophagoides pteronyssinus, are responsible for the immediate hypersensitivity reaction. although a large number of antigens and allergens was detected in a whole mite culture extract, only the major allergens of der i and ii groups have been extensively studied. much information on other important allergens remains to be accumulated. | 1995 | 7622766 |
| food-induced and occupational asthma due to barley flour. | occupational exposure to inhalant allergens may induce asthma but the presence of asthma after the ingestion of the allergen is rarely reported. | 1995 | 7648375 |
| house dust mite allergen levels in dust from schools with smooth and carpeted classroom floors. | a study was conducted to investigate the levels of house dust mite allergen der p i in classroom floor dust from 49 schools with smooth (n = 18) or carpeted (n = 31) floors. schools were located in the city of rotterdam (n = 29) and in a number of small communities in the province of gelderland (n = 20). data on building characteristics of the schools were obtained. dust samples were analysed for der p i content, the major allergen of the house dust mite dermatophagoides pteronyssinus. the resul ... | 1995 | 7648462 |
| house dust mite fauna in thailand. | house dust mites have been shown to be the most important source of allergen in thailand. the results of our initial mite survey were in conflict with previous data reported 20 years ago. to evaluate the current condition of mite fauna in thailand, we conducted a larger scale survey of house dust mites in dusts from three different parts of the country. a total of 630 mattress dust samples was collected from various types of housing from central, northern and northeastern parts of thailand. hous ... | 1995 | 7648463 |
| bioassay techniques for evaluating pesticides against dermatophagoides spp. (acari: pyroglyphidae). | three bioassay techniques for testing pesticides against the american house dust mite, dermatophagoides farinae hughes, and the european house dust mite, dermatophagoides pteronyssinus (trouessart), were evaluated using cypermethrin as a standard. all 3 bioassay techniques gave linear responses, and can be used for evaluation of different properties of compounds. the slide dip technique tests for contact activity, the plastic petri dish technique for residual activity on a nonporous surface, and ... | 1995 | 7650713 |
| detection of at least one high-molecular-mass, ige-binding component of the dust mite lepidoglyphus destructor. | we studied the allergen composition in an extract of the storage mite lepidoglyphus destructor. monoclonal antibodies (mabs) were raised against l. destructor by a standard hybridoma technique. in the subsequent screening, we concentrated on mabs fulfilling three criteria. first, in elisa, mabs were assessed against a panel of various mite species, and only those reacting exclusively with l. destructor extract were selected for further analyses. secondly, mabs were selected in immunoblotting acc ... | 1994 | 7653740 |
| optimization and characterization of freeze-dried multilamellar liposomes incorporating different standardized allergen extracts. | desensitization therapy for type i allergy is now current practice. liposomes have been proposed as a support for allergens to improve safety and effectiveness. the aim of this work was to optimize liposomal formulations of three different standardized allergen extracts and to test their allergenicity in vitro and in a preclinical trial. allergen extracts (dactylis glomerata, dermatophagoides pteronyssinus, and cat hair and dander) were associated with multilamellar liposomes of varying composit ... | 1994 | 7653744 |
| a study of the binding of immunoglobulin g and immunoglobulin e from children with bronchial asthma to peptides derived from group ii antigen of dermatophagoides pteronyssinus. | the peptides that were produced by the treatment of the purified group ii antigen of dermatophagoides pteronyssinus with cyanogen bromide, lysylendopeptidase, staphylococcus aureus v8 protease, or n-tosyl-l-phenylalanylchloromethyl ketone-treated trypsin were examined for their binding with igg and ige from children with bronchial asthma by immunoblotting analysis. both igg and ige bound to the peptides from the amino terminus to the 76th residue and the carboxyl terminal side from the 13th or 1 ... | 1993 | 7679489 |
| comparative ige responses to extracts of five species of house dust mite, using western blotting. | ige responses towards extracts of dermatophagoides pteronyssinus, d. farinae, d. microceras, euroglyphus maynei and gymnoglyphus longior have been evaluated with sera from a mite sensitive population and the international reference pool of sera, nibsc 82/528, using western blotting. using mite body and faecal extracts 21 of 29 mite protein bands responded to by sera were common to all five species of mite. all sera were unique with respect to proteins bound and species recognized. mite proteins ... | 1993 | 7680599 |
| comparative analysis of biological activities of der p i-derived peptides on fc epsilon receptor-bearing cells from dermatophagoides pteronyssinus-sensitive patients. | the ability of four uncoupled synthetic peptides (p52-71, p117-133, p176-187, p188-199) derived from der p i, a major allergen from the house dust mite dermatophagoides pteronyssinus (dpt) to stimulate fc epsilon r+ cells from dpt-sensitive patients was comparatively analysed. each free peptide may specifically stimulate basophils (fc epsilon ri+ cells) and platelets (fc epsilon rii+ cells) from patients with significant levels of anti-der p i ige antibodies; p52-71 and p117-133 appear the best ... | 1993 | 7682161 |
| effect of salbutamol, fenoterol, and sodium cromoglycate on the release of heparin from sensitized human lung fragments challenged with dermatophagoides pteronyssinus allergen. | heparin from degranulating mast cells influences a wide range of cellular and humoral reactions associated with allergic inflammation and asthma. agents that inhibit mast cell degranulation may therefore compromise the moderating effects of heparin in the tissues and result in worsening inflammation and other associated pathology. this study measures heparin release from allergen-challenged human lung tissue and compares the effect of the mast cell stabilizing beta 2-agonists, salbutamol and fen ... | 1993 | 7683196 |
| effect of passive sensitization on the mechanical activity of human isolated bronchial smooth muscle induced by substance p, neurokinin a and vip. | 1. the effect of passive sensitization on the mechanical activity of human isolated bronchial smooth muscle induced by the following neuropeptides substance p (sp), neurokinin a (nka) and vasoactive intestinal peptide (vip) was studied both in the absence and in the presence of the neutral endopeptidase (nep) inhibitor, phosphoramidon. 2. cumulative concentration-response curves (ccrc) to these neuropeptides were constructed in human passively sensitized isolated bronchial rings and compared to ... | 1993 | 7684296 |
| expression of lymphocytes fc epsilon rii/cd23 in allergic children undergoing hyposensitization. | owing to the proposed role of fc epsilon rii/cd23 in allergic diseases, we analyzed the expression of this receptor on peripheral blood lymphocytes (pan-b, pan-t and cd4+ or cd8+ t cells) and its autoproteolytic product scd23 in serum. this was done in 10 asthmatic children allergic to dermatophagoides pteronyssinus (dpt) before and 6 weeks after hyposensitization. facs analysis of double, direct immunofluorescence staining of the whole blood revealed an elevated percentage of fc epsilon rii/cd2 ... | 1993 | 7685220 |
| t cell epitopes of house dust mite major allergen der p ii. | recent work has indicated the significance of il-4- and il-5-secreting allergen-specific human th2 lymphocytes in the control of immune responses to allergens in atopic individuals. the precise allergenic epitopes that activate these allergen-specific th2 cells are, however, hardly known. we analyzed the epitope-specificity of t lymphocytes specific for der p ii, one of the major allergens of house dust mite dermatophagoides pteronyssinus. using a panel of overlapping synthetic peptides that spa ... | 1993 | 7688399 |
| human in vitro experimental model for cd4+ t cell targeted immunotherapy to house dust mite. | cd4+ t cells play a critical role in the initiation and potentiation of the allergic immune response. development of allergen-mediated hyposensitization therapies directed at this cell type requires two key steps: (1) identification of the epitopes that are crucial for activating the t-cell response and (2) definition of the specificity of the hla-d region molecules that restrict t-cell recognition of these epitopes. we have located the major t-cell determinants of the group ii allergen of the h ... | 1993 | 7690528 |
| antigen avoidance in a mountain environment: influence on basophil releasability in children with allergic asthma. | the influence of natural antigen avoidance in an environment free of relevant allergens (istituto pio xii, misurina, italian alps, 1756 m) and of antigen exposure (sea level) on basophil releasability, as well as on bronchial hyperreactivity (bhr) and specific ige serum level, were investigated in a group of children with asthma who were allergic to dermatophagoides pteronyssinus. | 1993 | 7693784 |
| optimization of skin testing. i. choosing allergen concentrations and cutoff values by factorial design. | standardized extracts of phleum pratensis (grass) and dermatophagoides pteronyssinus (house-dust mite) were used as test allergens for multiple regression in order to determine optimum concentrations and cutoff values with regard to diagnostic capacity and safety. if a rast value of class 1 or more was taken as an indication of sensitization, it was found that the optimum concentrations for the detection of sensitization are in the range 10-100 bu/ml and 1500-10,000 bu/ml for intracutaneous test ... | 1993 | 7694518 |
| specificity of elisa for igg subclass antibodies against inhalant antigens in early childhood. | elisa is increasingly used to measure antibodies in new circumstances. recently, it has been applied to the measurement of igg subclass antibodies against common antigens in early childhood. these studies have raised concerns about the specificity of some of these assays. this paper details the results of experiments which have assessed the specificity of igg1 binding to allergens of dust mite (dermatophagoides pteronyssinus) and ryegrass (lolium perenne) pollen by inhibition elisa in the sera o ... | 1994 | 7695060 |
| peak-flow variability in asthmatic children is not related to wall-to-wall carpeting on classroom floors. | the hypothesis was tested that wall-to-wall carpets on school classroom floors have a negative effect on the respiratory health of asthmatic children. asthmatic patients (n = 98) were selected from the records of the sophia children's hospital in rotterdam. the patients were between 5 and 11 years old. all children had peak-flow measurements three times a day for a 1-month period. the parents of the children completed a diary in which respiratory symptoms and medication use were recorded daily f ... | 1994 | 7695061 |
| the profiles of interleukin (il)-2, il-6, and interferon-gamma production by peripheral blood mononuclear cells from house-dust-mite-allergic patients: a role for il-6 in allergic disease. | we have developed a model to measure cytokine production by peripheral blood mononuclear cells (pbmc) in vitro. in this report, we examine the production of interleukin-2 (il-2), il-6, and interferon-gamma (ifn-gamma) by pbmc of house-dust-mite (dermatophagoides pteronyssinus)-allergic subjects. when stimulated with specific allergen (d. pteronyssinus), pbmc of patients produced significant levels of il-2 and high levels of il-6, but little or no ifn-gamma. nonatopic control pbmc also produced i ... | 1994 | 7695065 |
| augmentation of permeability in the bronchial epithelium by the house dust mite allergen der p1. | sequence analyses have revealed the existence of homology between certain aeroallergens and proteolytic enzymes. this homology can be expressed functionally, but its significance to airway pathophysiology is unknown. studies with madin-darby canine kidney cells and canine tracheal epithelial cells grown on plastic substrata or matrix proteins suggest that der p1, a major allergen from the house dust mite dermatophagoides pteronyssinus and a cysteine proteinase, or the unfractionated growth mediu ... | 1995 | 7695916 |
| comparative detection of mite allergens in house dust of homes in moscow by enzyme-linked immunosorbent assay and acarologic analysis. | the present study revealed that 73% of surveyed apartments in moscow whose residents included children with the atopic form of bronchial asthma and sensitization to dermatophagoides pteronyssinus allergens were infested with the pyroglyphid mites d. pteronyssinus and d. farinae. the number of mites in the surveyed apartments varied between 0 and 154 mites/g of dust for d. pteronyssinus and between 0 and 162 mites/g of dust for d. farinae. the levels of mite allergens in these apartments ranged f ... | 1994 | 7709990 |
| sensitization to inhalant allergens in wheezing infants is predictive of the development of infantile asthma. | early recognition of infantile asthma in wheezing infants is a major problem for physicians. we investigated whether detection of early sensitization to inhalant allergens would be useful to identify those wheezing infants who are likely to develop asthma. a total of 67 infants (aged 1-25 months) hospitalized for a wheezing episode were initially tested for reactivity to inhalant allergens by both skin prick test and in vitro measurement of specific ige antibodies (phadiatop). thirty-seven of th ... | 1994 | 7709993 |
| house dust mite (dermatophagoides farinae and dermatophagoides pteronyssinus) prevalence in the rooms and hallways of a tertiary care hospital. | house dust mites, dermatophagoides farinae and dermatophagoides pteronyssinus, are important components in the development of asthma. | 1995 | 7722158 |
| eosinophilic pustular folliculitis in three atopic children with hypersensitivity to dermatophagoides pteronyssinus. | three children will be described who present recurrent episodes of pruritic papulopustular follicular lesions on the face, the extremities and the trunk. the episodes lasted for 1-3 months with intermittent remission. each flare was accompanied by hypereosinophilia and an increased total ige titer. rast and prick tests were positive for dermatophagoides pteronyssinus (dpt). laboratory tests disclosed no infectious or parasitic etiology. histological examination showed eosinophilic pustular folli ... | 1995 | 7727841 |
| dietary antioxidant vitamin intake and lung function in the general population. | we have investigated the relation between lung function and dietary intake of the antioxidant vitamins c and e in the general population in a cross-sectional survey of a random sample of adults from the electoral register of an administrative area of nottingham. in 2,633 subjects 18 to 70 yr of age, we measured fev1 and fvc, allergen skin sensitivity to grass pollen, cat fur, and dermatophagoides pteronyssinus, pack-years smoking exposure by personal recall, and usual dietary intake of vitamins ... | 1995 | 7735589 |
| canine atopic disease: the prevalence of positive intradermal skin tests at two sites in the north and south of great britain. | results of intradermal skin test responses to the same panel of 53 allergens were compared in 118 dogs with atopic disease presented at two geographical centres, edinburgh (87 cases) and london (31 cases). the allergens most commonly positive at both centres were human dander and dermatophagoides farinae, but positive tests to all of the allergens used occurred in at least one case. the mean number of allergens to which positive tests resulted in atopic dogs was 5.126 (edinburgh) and 5.129 (lond ... | 1995 | 7747407 |
| il-10 secretion of allergen-specific skin-derived t cells correlates positively with that of the th2 cytokines il-4 and il-5. | in atopic individuals, allergen-specific cd4+ t lymphocytes often belong to the t-helper 2 (th2) subset as they secrete the marker cytokines interleukin-4 (il-4) and il-5 but not interferon-gamma (inf-gamma). il-10 is a cytokine the production of which, in the mouse system has been described to be restricted to the th2 subset, but in the human was found to be produced by both th1 and th2 t cell clones (tcc). we have recently shown that house dust mite antigen (dermatophagoides pteronyssinus)-spe ... | 1994 | 7749574 |
| natural history of ige antibodies in children at risk for atopy. | the relationship between atopic diseases and high serum ige levels has been emphasized since the mid-sixties, when ige antibodies were discovered. a number of environmental factors, such as the type of feeding, passive smoking, viral infections, early mold, house dust mite and pet fur exposure modulate ige synthesis and affect the development of atopic diseases. | 1995 | 7749975 |
| humoral response to subcutaneous, oral, and nasal immunotherapy for allergic rhinitis due to dermatophagoides pteronyssinus. | we investigated variations in total ige, and specific ige, igg, and igg4 for dermatophagoides pteronyssinus in 57 patients with perennial rhinitis due to house dust mite allergy in an open controlled study: 43 subjects received immunotherapy (17 subcutaneous, 14 sublingual, and 12 local immunotherapy) and 14 were controls. the results were compared with the clinical course to determine possible associations between serum and clinical changes. subcutaneous, but not sublingual and nasal, immunothe ... | 1993 | 7755664 |
| hla-dr expression is induced on keratinocytes in delayed hypersensitivity but not in allergen induced late-phase reactions. | in view of increasing evidence suggesting an active immunoregulatory role of the skin keratinocytes and the observation that the differentiation of allergen specific t lymphocytes is critical in the development of allergy, we evaluated epidermal expression of hla-dr antigen in skin reactions induced with an atopen (house dust mite) and with an non-atopic antigen (hemocyanin). two groups of patients with house dust mite (dermatophagoides pteronyssinus [der p]) allergy were compared, one group was ... | 1995 | 7788573 |
| characterization of der p v allergen, cdna analysis, and ige-mediated reactivity to the recombinant protein. | a lambda gt11 library for cdna from dermatophagoides pteronyssinus was screened by plaque immunoassay, and a number of related clones that produced ige-binding proteins were isolated. their sequences were homologous to that of a cdna described previously, which contained a reading frame encoding a 17 kd polypeptide and which as determined by serologic analysis corresponded to a protein with relative molecular mass of 14 kd in mite extracts. the cdna from the lambda gt11 clones was truncated so i ... | 1994 | 7798547 |
| [the action of insect developmental regulators on the housedust mites dermatophagoides pteronyssinus (trouessart, 1897) and d. farinae hughes, 1961 (acari: pyroglyphidae)]. | whether insect growth regulators, such as methoprene, telflubenzuron and flufenoxuron, can be used to suppress the populations of the house dust mites d. pteronyssinus and d. farinae has been studied in the laboratory setting. the most potent agent has been found to be methoprene used in concentrations of 0.05 = 0.1%, in particular. flufenoxuron at a concentration of < 0.1% has been shown to stimulate the reproduction of house dust mites. | 2016 | 7799849 |
| environmental and bronchoalveolar lavage dermatophagoides pteronyssinus antigen levels in atopic asthmatics. | overnight environmental home exposure to dermatophagoides pteronyssinus in ige-sensitized individuals is often clinically associated with increased morning symptoms of rhinitis and/or asthma. we have investigated whether household exposure to d. pteronyssinus is associated with the presence of immunoreactive d. pteronyssinus i antigen (der p i) in bronchoalveolar lavage (bal) fluid in nine atopic asthmatics sensitized to d. pteronyssinus. significant environmental concentrations of d. pteronyssi ... | 1995 | 7812575 |
| mite antigen in house dust: relationship with different housing characteristics in the netherlands. | as part of a case-controlled study on the relationship between home dampness and respiratory symptoms of children, the concentration of the major allergen of dermatophagoides pteronyssinus (der p i) in floor dust and mattress dust in 516 dwellings in the netherlands was measured. a checklist, completed by the investigators, was used to obtain information on home and occupant characteristics, which may have an impact on the der p i concentration in house dust. the geometric mean mite antigen conc ... | 1994 | 7812886 |
| dermatophagoides pteronyssinus ii-induced interleukin-4 and interferon-gamma expression by freshly isolated lymphocytes of atopic individuals. | cytokines are known to play a major role in mediating many of the immunological and pathological features of allergic disease. much of our understanding of cytokine production in response to allergens has come from studying allergen-specific t cell clones following long-term in vitro culture. this has largely been due to the lack of sufficiently sensitive assays to measure allergen-induced cytokine production by freshly isolated peripheral blood mononuclear cells (pbmcs). here we have used the p ... | 1994 | 7812889 |
| a comparative study of three serine proteases from dermatophagoides pteronyssinus and d. farinae. | studies have shown that the dust mites dermatophagoides pteronyssinus and d. farinae contain several serine proteases, two of which have been shown to be allergenic, and to include trypsin and chymotrypsin, corresponding to the groups iii and vi mite allergens. however, mites also contain other serine proteases, and the data reported in this study show that an elastase-like enzyme is present in both species. this enzyme was differentiated from the other serine proteases, particularly chymotrypsi ... | 1994 | 7825723 |
| comparison of two epidemiological protocols for measuring airway responsiveness and allergic sensitivity in adults. | in recent years, airway responsiveness has commonly been measured in epidemiological studies using one of two methods. in one method, histamine is administered via a handheld devilbiss nebulizer and in the other, methacholine is administered via a dosimeter. allergic sensitivity has commonly been measured by either the allergen droplet method or by phazet. we wanted to assess the comparability of airway responsiveness and of allergic sensitivity measured by both methods. a total of 48 volunteers ... | 1994 | 7828688 |
| benzyl-benzoate foam: effects on mite allergens in mattress, serum and nasal secretory ige to dermatophagoides pteronyssinus, and bronchial hyperreactivity in children with allergic asthma. | home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children istituto pio xii (located in the italian alps in an environment free of mites) and went back to their own home for the christmas and easter holidays. a further group of 8 children, whose mattresses received no treatment, was kept as an absolute control. two days after ... | 1994 | 7838620 |
| immunologic evaluation of 24 month course of sublingual immunotherapy. | 58 patients under 12 years of age, positive to mites (dermatophagoides pteronyssinus and d. farinae) according to prick, in vitro specific ige and challenge tests, suffering from asthma and rhinitis, have been randomly assigned on a double blind basis to receive per os either a biologically standardized extract of mites (active therapy ta = 30 patients) or a saline buffered solution (placebo tp = 28 patients). the serologic results are interesting. the specific ige level differences of significa ... | 2004 | 7840022 |
| mite-antigen-stimulated cytokine production by peripheral blood mononuclear cells of atopic dermatitis patients with positive mite patch tests. | to investigate possible involvement of th1-type immunoreaction in the development of skin lesions of atopic dermatitis (ad), we measured mite-antigen-stimulated production of il-2, il-4 and ifn-gamma, using peripheral blood mononuclear cells (pbmc) obtained from 23 patients with ad who developed positive patch test reactions to house dust mite antigens extracted from dermatophagoides pteronyssinus (dp). incubation of these pbmc with the dp antigen for 72 h produced marked secretion of il-2 and i ... | 1994 | 7842675 |
| filtration of airborne allergens in various households. | the filtration system investigated in this study uses the thermic convection caused by radiators for the adsorption of airborne particles. the effect of this filtration system on the reduction of clinical symptoms of allergic bronchial asthma was tested as well as its capability in retaining airborne allergens, in particular those of the house dust mite dermatophagoides pteronyssinus (d. pter.), which are responsible for this special kind of asthma. dust samples were taken before and after the h ... | 1994 | 7848501 |
| atopic sensitization in children of somali immigrants in italy. | children of immigrants are known to be at greater risk for developing allergic manifestations than the population in general. in this study we observed children of somali origin living in italy in order to find plausible explanations for the high risk of allergic disease in immigrants. fifty-two children aged 0-14 years (mean = 6.7 years) were examined during the spring season. the mothers of the children were asked to fill in a questionnaire on symptoms and signs of atopic diseases and the fami ... | 1994 | 7850033 |
| relationship between facilitated allergen presentation and the presence of allergen-specific ige in serum of atopic patients. | allergen presentation to allergen-specific t cells can be facilitated when ige-allergen complexes are endocytosed by antigen-presenting cells (apc) after binding to the low-affinity fc epsilon r type ii (cd23). here we present a study on the relative capabilities of sera of atopic patients to mediate facilitated antigen presentation (fap). to this aim fap was studied in an in vitro model in which cd23-expressing epstein-barr virus (ebv)-b cells act as apc to t lymphocyte clones (tlc) that are sp ... | 1995 | 7851024 |
| [effect of cetirizine therapy on the rate of adverse reactions to specific desensitization]. | an effect of cetirizine--one of antihistaminic agents--on the rate of adverse reactions to the specific desensitization has been evaluated in patients with atopic respiratory diseases. the study included 270 patients desensitized in 1988-1993 for the atopic diseases due to hypersensitivity to grass pollens and dermatophagoides pteronyssinus. standard alvac-p. pollinex, and alvac-s hdm vaccines have been used. occurrence and severity of the adverse reactions noted during 3,368 injections of vacci ... | 2013 | 7854995 |
| allergens of the house dust mite, dermatophagoides pteronyssinus, in patients with mite allergic rhinitis: a clinical investigation by intracutaneous skin tests and nasal provocation tests. | to determine the allergens of mite allergic rhinitis, we studied 31 patients with mite allergic rhinitis by skin tests and nasal provocation tests (15 for skin and 16 for nasal tests) using 6 fractions of dermatophagoides pteronyssinus (dp) extract differing in molecular weights (15, 25, 32, 53, 95 and 190 kdmw). in skin testing, patients showed intense positive reactions to the fractions of 15, 25, 32, 95 and 190 kdmw, among which the most patients showed positive reactions to the fractions of ... | 1994 | 7863799 |
| comparison of the levels of the major allergens der p i and der p ii in standardized extracts of the house dust mite, dermatophagoides pteronyssinus. | allergy to the house dust mite dermatophagoides pteronyssinus is mediated by ige to the major allergens der p i and der p ii in the majority of mite-allergic patients. in recent years, standardized preparations of d. pteronyssinus, commercially available from several sources, have become widely used for the diagnosis and immunotherapy of mite allergy. as standardization implies uniformity of allergen composition and potency, we directly compared the absolute and relative quantities of der p i an ... | 1994 | 7874602 |
| house dust mite allergen (der p i) and respiratory symptoms in children: a case-control study. | the association between house dust mite allergen in house dust and childhood respiratory symptoms was investigated in a case-control study of 259 children with reported chronic respiratory symptoms and 257 control children without reported respiratory symptoms. the der p i concentration in floor dust of the living room and bedroom and in mattress dust was determined using an enzyme immunoassay. venous blood samples were taken from all children for serum ige determination against house dust mite ... | 1994 | 7874605 |
| the influence of increased bronchial responsiveness, atopy, and serum ige on decline in fev1. a longitudinal study in the elderly. | we have performed a 4-yr prospective survey of the association of allergen skin test positivity, total serum immunoglobulin e (ige), and bronchial responsiveness to methacholine, with longitudinal decline in fev1, in subjects over 65 yr of age. in 1987, 324 subjects completed a respiratory questionnaire, and underwent measurement of fev1 and fvc, methacholine challenge, skin prick testing (to dermatophagoides pteronyssinus, cat fur, mixed grasses, and aspergillus fumigatus) and estimation of tot ... | 1995 | 7881652 |
| relationship between nasal resistance and airway hyperreactivity following nasal provocation with dermatophagoides pteronyssinus in allergic rhinitis. | to determine whether nasal allergic symptoms can cause bronchial hyperresponsiveness to methacholine, 30 subjects with allergic rhinitis (22 with allergic rhinitis and 8 with allergic asthmatic rhinitis) were studied. all subjects were skin test positive to dermatophagoides pteronyssinus (dp) and underwent nasal allergic provocation with dp. after provocation, there was a severe nasal allergic reaction in the challenged nostril with a significant increase in nasal resistance both immediately and ... | 1995 | 7888791 |
| eosinophil differentiation and hypodensity alteration activities in dermatophagoides pteronyssinus-stimulated mononuclear cell culture supernatants derived from asthmatics. | we investigated the contributing effect of dermatophagoides pteronyssinus-stimulated mononuclear cell (mnc) cultured supernatants on the differentiation and density alteration of eosinophils. mnc, obtained from either normal subjects or asthmatics, were cultured with or without d. pteronyssinus. the supernatants were tested for the activity of eosinophil differentiation and density alteration. the results showed a significant increase in eosinophil differentiation activity in d. pteronyssinus-st ... | 1995 | 7888793 |
| allergen-antibody complexes in the treatment of dermatophagoides pteronyssinus hypersensitivity diseases. | 1994 | 7889421 | |
| cow milk allergy within the spectrum of atopic disorders. | in order to examine the relationship between cow milk allergy (cma) and atopic disorders in childhood, a consecutive group of 42 infants with ige mediated cma was followed for at least 2 years. the incidence of sensitization to common food and inhalant antigens and the development of eczema, asthma, and food allergies was examined for the cohort and compared between patients whose cma remitted and those with persistent disease. in this cohort the prevalence of eczema was 57%, asthma 69%, egg all ... | 1994 | 7889427 |
| allergen-induced cd23 on cd4+ t lymphocytes and cd21 on b lymphocytes in patients with allergic asthma: evidence and regulation. | interaction of cd4+ t cells and b cells is necessary for ige production. it has been recently demonstrated that cell surface antigen cd21 is a ligand for cd23 (fc epsilon rii) and that the pairing of these molecules may participate in the control of ige production. in this study we investigated the effect of the dermatophagoides pteronyssinus (dpt) allergen and recombinant interleukin(ril)-4 on the expression of cd21 and cd23 on t and b cells of asthmatic patients allergic to dpt and of healthy ... | 1994 | 7910139 |
| genetic linkage of t-cell receptor alpha/delta complex to specific ige responses. | ige responses to inhaled proteins underlie the clinical syndrome of allergic (atopic) asthma and rhinitis. we have investigated genetic linkage between specific ige reactions to highly purified major allergens and the t-cell receptor (tcr) alpha and beta gene complexes on chromosome 14 and 7, respectively. antigens tested included highly purified proteins from the housedust mite dermatophagoides pteronyssinus, the domestic cat and dog, grass pollen, and the mould alternaria alternata. affected s ... | 1994 | 7911920 |
| evaluation of the potency of allergenic extracts by inhibition of igg-antibody binding. | a method is described for the in vitro potency evaluation of allergenic extracts by using their capacity of binding to specific human igg antibodies. the results obtained with this inhibition-type enzyme immunoassay are compared with the analyses by the customary method of ige antibody binding. a large series of allergenic protein fractions from the pollen of the gramineae, olea europea, parietaria judaica, and from the dust mite dermatophagoides pteronyssinus as well as from cat dander and pean ... | 1994 | 7917232 |
| cloning and characterization of a major allergen of the house dust mite, dermatophagoides pteronyssinus, homologous with glutathione s-transferase. | a major allergen of the house dust mite, dermatophagoides pteronyssinus, has been identified and characterized from a lambda gt11 cdna library of the mite. ige antibodies from the sera of allergic patients that recognise the cloned polypeptide bind to an approximately 26 kda polypeptide on a western blot of reduced mite polypeptides. nucleotides sequencing of the clone revealed a 219 amino acid open reading frame encoding a protein with a derived molecular mass of 25,589 da and a pi of 6.3. comp ... | 1994 | 7918651 |
| human ige in scid mice reconstituted with peripheral blood mononuclear cells from dermatophagoides pteronyssinus-sensitive patients. | scid mice were reconstituted with purified peripheral blood mononuclear cells from patients sensitive to dermatophagoides pteronyssinus (dpt). after immunization with a low dose of the related allergen, these human (hu)-scid mice may develop a specific ige response. by using an ige-dependent platelet assay and the related allergen dpt, the human ige was demonstrated to be functional. indeed a high correlation was obtained between both parameters. no rise in human ige level was detected within 3 ... | 1994 | 7930597 |
| [the effectiveness of russian insecticidal preparations in the form of aerosols for the house dust mite dermatophagoides pteronyssinus (trouessart, 1897) and d. farinae, hugnes, 1961 (acari: pyroglyphidae)]. | 2009 | 7935190 | |
| dietary sodium intake and the risk of airway hyperreactivity in a random adult population. | high dietary sodium intake has been identified as a potential cause of asthma and airway hyperreactivity. this study was designed to test the hypothesis that dietary sodium intake is an independent determinant of the risk of hyperreactivity in the general population, and to assess the role of atopy in the association between these factors. | 1994 | 7940426 |
| comparison of three in vitro assays for serum ige with skin testing in asthmatic children. | the diagnostic performance of three commercial assay kits [phadezym rast (phrast), pharmacia cap system (cap), and multiple chemiluminescent assay (cla-mast)] for measuring serum-specific ige was evaluated and compared using intradermal skin testing or skin prick testing as reference standards. serum samples were obtained from allergic patients who were tested with either intradermal skin tests or skin prick tests (96 and 49 subjects, respectively). six different allergen extracts were tested: d ... | 1994 | 7944001 |
| [breeding control and immobilizing effects of wood microingredients on house dust mites]. | the possible effects of essential oils as wood microingredients on house dust mites (tyrophagus putrescentiae, dermatophagoides farinae and dermatophagoides pteronyssinus) were investigated. 1. whether small pieces of 5 types of wood had any control effect on mite breeding was studied. mite breeding using only normal feed was compared with breeding using feed mixed with small pieces of wood. in addition, mite breeding using feed mixed with small pieces of wood with no essential oil was studied. ... | 1994 | 7949285 |
| [a new test of specific bronchial provocation with powder allergens in diagnosis of allergic diseases]. | the value of the melillo method of the specific bronchial provocation test (sbpt) using house dust mite allergen was examined. the studies were carried out on 33 mild asthma patients, found to be sensitive to house dust mite by the case history and positive skin test with dermatophagoides pteronyssinus. the lung function tests of most of the patients were within normal range. a positive bronchial response to allergen was observed in 26 persons (79% of patients examined), dual reaction in 16, onl ... | 1994 | 7951085 |
| effect of regular terbutaline and budesonide on bronchial reactivity to allergen challenge. | there is a transient rebound increase in bronchial reactivity to histamine and methacholine following regular treatment with an inhaled beta 2-agonist. we set out to determine whether the response to allergen was increased after cessation of regular inhaled terbutaline and whether concomitant inhaled budesonide modifies this response. in a double-blind, double-dummy, parallel group design we studied 41 subjects (37 evaluable) with mild asthma who were allergic to dermatophagoides pteronyssinus, ... | 1994 | 7952551 |
| [topical nasal immunotherapy with dermatophagoides pteronyssinus extract]. | 2004 | 7976962 | |
| immune reactivity to der p i and der p ii in house dust mite sensitive patients attending paediatric and adult allergy clinics. | a comparison was made of immune responses to house dust mite allergens in symptomatic patients from paediatric and adult allergy clinics. ige-specific immune reactivity to dermatophagoides pteronyssinus was examined by western blotting and, for der p i and der p ii, by radioimmune dot-blot using purified allergens. nineteen mite-sensitive children (mean age 9 years) and 26 adults (mean age 31 years) were compared. positive ige responses by dot-blot were found to der p i and der p ii in 79% of ch ... | 1994 | 7982123 |
| allergenic characterization of acarus siro and tyrophagus putrescentiae and their crossreactivity with lepidoglyphus destructor and dermatophagoides pteronyssinus. | allergenic components in extracts of acarus siro and tyrophagus putrescentiae were identified by sodium dodecyl sulphate-polyacrylamide (sds-page) and immunoblotting. five and four allergenic components, respectively, were visualized with sera from farmers sensitized to storage mites. the highest frequency of ige-binding was to a 15 kda component of a. siro (7/9 sera) and a 16 kda component of t. putrescentiae (23/29 sera). the allergenic crossreactivity of a. siro and t. putrescentiae with lepi ... | 1994 | 7982124 |
| effect of nitrogen dioxide and sulphur dioxide on airway response of mild asthmatic patients to allergen inhalation. | air pollution may enhance the airway response of asthmatic subjects to allergen inhalation. to test the hypothesis that sulphur dioxide and nitrogen dioxide alone or in combination could have a contributory role, we have studied the effect of 6 h exposure to air, 200 parts per billion (ppb) sulphur dioxide, 400 ppb nitrogen dioxide, and the two gases together on the airway response to inhaled allergen in ten volunteers with mild atopic asthma. the subjects were exposed to the gases in random ord ... | 1994 | 7996960 |
| antinuclear antibodies in patients with atopic dermatitis and severe facial lesions. | in adult patients with atopic dermatitis (ad), the presence of autoantibodies such as anti-ige and antinuclear antibodies (ana) has been demonstrated. the patients may have altered immune regulation. | 1994 | 8003783 |
| postallergen inhaled budesonide reduces late asthmatic response and inhibits the associated increase of airway responsiveness to methacholine in asthmatics. | to determine whether inhaled budesonide given after allergen inhalation challenge inhibits the late asthmatic response (lar) and/or the associated increase of airway responsiveness to methacholine, we performed a double-blind randomized cross-over study in 12 adult asthmatics (eight male, four female; mean age, 20.3 yr; range, 18 to 29 yr) sensitized to dermatophagoides pteronyssinus (dp) previously shown to develop early and late asthmatic response to allergen challenge with dp. on different da ... | 1994 | 8004297 |
| cloning and sequencing of the dermatophagoides pteronyssinus group iii allergen, der p iii. | house dust mites are widely recognized as major factors involved in the triggering of allergic diseases such as asthma. it is now apparent that the group iii allergens of the dermatophagoides mite species may play a significant role in a number of house dust mite allergic cases. natural der p iii was isolated by gel filtration of salt precipitated dermatophagoides pteronyssinus extract and as reported previously ran as a doublet of mr 28 and 30 k on sodium dodecyl sulphate-polyacrylamide gel ele ... | 1994 | 8012853 |
| [the efficacy of long-term specific immunotherapy for dermatophagoides pteronyssinus in patients with atopic dermatitis]. | the aim of this study was to evaluate the efficacy of hyposensitization therapy with dermatophagoides pteronyssinus vaccine in patients with moderate and severe atopic dermatitis and sensitization to house mite dust. we studied 32 patients who showed strongly positive skin prick test and high levels of circulating specific ige to dermatophagoides pteronyssinus. all the patients were treated with sodium alginated dialyzed allergenic extract (bayropharm, milan), realized by increasing progressivel ... | 1994 | 8023005 |
| [current trends in the specific immunotherapy for allergic syndromes due to dermatophagoides pteronyssinus]. | house dust mites of the species dermatophagoides pteronyssinus are among the most prevalent perennial allergens. measurement of allergen exposure is so crucial to establish the natural history of the allergic reaction. the most common clinical manifestations induced by dermatophagoides are perennial asthma and perennial rhinitis. recently there are a number of studies indicating that a high degree of exposure to house dust mites may represent a risk factor for severe disease in patients with ato ... | 1994 | 8023008 |
| mite allergen exposure is a risk for the incidence of specific sensitization. | mite allergen exposure is essential for the process of specific allergic sensitization. however, it is not clear whether incidence of specific sensitization at school age depends on the level of mite antigen exposure. therefore the relationship between mite allergen exposure and incidence of specific sensitization was investigated. | 1994 | 8027498 |
| use of a specific oral hyposensitization therapy to dermatophagoides pteronyssinus in children with atopic dermatitis. | the aim of the present study was to evaluate the efficacy of an oral specific hyposensitization therapy in children with atopic dermatitis and positive prick skin tests and/or rast to dermatophagoides pteronyssinus (d.pt.). a total of 60 patients, in three different clinical groups, were selected for a three years clinical trial. group a: children with atopic dermatitis and allergic asthma and/or rhinitis; groups b and c: children with exclusively atopic dermatitis. groups a and b received speci ... | 2006 | 8030579 |
| do latex allergens potentiate other skin tests? | we report the case of a 33 year old atopic female patient, who worked for the last 4 years as a cleaner in the surgical area of a hospital. one year after starting the work in this area, the patient noticed upper respiratory symptoms and soon later dyspnea immediately after entering the operating room. other allergic symptoms were perennial rhinoconjunctivitis and urticaria after contact with peaches. common skin prick tests were positive for dermatophagoides pteronyssinus. fifteen min later a s ... | 1994 | 8030583 |
| airways of allergic rhinitics are 'primed' to repeated allergen inhalation challenge. | the hypothesis that repeated exposure to a specific allergen will further increase bronchial responsiveness to that allergen is supported by indirect evidence. however, it has not been tested as intensely in the laboratory setting, and in some cases, conflicting results are presented. in order to test the hypothesis in the atopic subjects, allergen inhalation challenge tests were performed in 29 house dust mite (dermatophagoides pteronyssinus) sensitive subjects with allergic rhinitis. nine subj ... | 1994 | 8039019 |
| sensitization to storage mites in house dust mite (dermatophagoides pteronyssinus) allergic patients. comparison of a rural and an urban population. | in this study, sera collected from 50 patients (24 females, 26 males) with type i allergy to house dust mite (dermatophagoides pteronyssinus) were investigated for ige antibodies specific for eight different mite species including storage mites of the families pyroglyphidae, glycyphagidae and acaridae. according to their environment the patients were divided into two groups. group i consisted of 24 (11 women, 13 men) farmers working and living in rural regions of austria (styria, lower austria), ... | 1994 | 8039020 |
| asthma, allergy and atopy in southern chinese school students. | in order to determine the prevalence of asthma, allergy and atopy in southern china and the relative importance of atopy and parental history in predicting asthma and allergic diseases, we carried out a cross-sectional study on 737 secondary school students aged 12-20 (492 boys, 245 girls; mean age = 16.4 years, sd = 1.8 years) in the city of san bu, guangdong, china. standard questionnaires on respiratory and allergic symptoms were distributed for completion by parents with an overall response ... | 1994 | 8039021 |
| ige to food allergens are highly prevalent in patients allergic to pollens, with and without symptoms of food allergy. | serum samples from 274 patients allergic to one or more of three pollens (birch, grass, mugwort), from 36 patients allergic to cat and/or dermatophagoides pteronyssinus but not to pollen and from 55 non-allergic controls, as well as 20 cord blood samples, were examined for specific ige to six 'pollen-associated' food allergens by using a new sensitive assay (cap). a questionnaire asking for reactions to food was also sent to all patients. in the pollen group, 111 patients (47%) were positive (> ... | 1994 | 8039023 |
| changes in nasal specific ige to mites after periods of allergen exposure-avoidance: a comparison with serum levels. | variations of serum and nasal specific ige to dermatophagoides pteronyssinus (der p) during alternate periods of antigen avoidance-exposure have been evaluated with an open design in a group of allergic children with asthma and rhinitis at the residential house istituto pio xii (misurina, bl, italy), at 1756 m, in the italian dolomites. a method based on direct incubation of allergen coupled substrate on the nasal mucosa has been employed to evaluate the levels of nasal ige. serum specific ige d ... | 1994 | 8039025 |