Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [evaluation of soil sanitation on poznan beaches based on helminth examination]. | it was proved that the soil of recreational areas can be potential source of human geohelminthiosis. the eggs of ascaris lumbricoides and trichocephalus trichiurus as well as of toxocara canis were found on the beaches of poznań lakes. | 1995 | 7638966 |
| occurrence of interleukin-5 production by cd4- cd8- (double-negative) t cells in lungs of both normal and congenitally athymic nude mice infected with toxocara canis. | we studied cells in the lungs of balb/c and balb/c-nu/nu (nude) mice infected with toxocara canis, which produced interleukin-5 (il-5) in in vitro culture with larval excretory-secretory antigen (esag). the proportion of cd4+/cd8+/cd4- cd8- cells in lungs of both balb/c and nude mice was unchanged before and after infection with t. canis. panning and complement-mediated lysis using monoclonal antibody (mab) to cd4 showed that cd4+ cells in the lung from both mice produced il-5. anti-cd4 mab supp ... | 1995 | 7642218 |
| [familial seroepidemiology of toxocariasis]. | with the objective of defining the intrafamiliar distribution pattern of the infection and illness caused by toxocara sp., 78 infected families (356 people) were studied for 30 months. at the same time 28 families free of infection were studied, as a control group (97 people). the socioeconomic level was analyzed according to a modified graffar index. contac with canine and feline pets, and antecedents of geophagia and onichophagia were found to be risk factors which would facilitate the infecti ... | 1994 | 7654285 |
| mobility inhibition and nematocidal activity of asarone and related phenylpropanoids on second-stage larvae of toxocara canis. | the in vitro effect of asarone, the nematocidal principle of the rhizome of acorus calamus, on second-stage larvae of toxocara canis is composed of two independent actions: one is a fast acting inhibition of the larval mobility and the other is a slow acting larvicidal action. mobility of the larvae was rapidly inhibited when they were incubated with asarone. dye exclusion assay revealed that larvae were alive at this stage, and their mobility was restored after the first inhibition, suggesting ... | 1995 | 7655436 |
| toxocara canis: ultrastructural aspects of larval moulting in the maturing eggs. | the morphology of the surface of toxocara canis larvae, developing in the eggs to reach infectivity, has been studied for the first time at an electron microscopical level. in most 11-day and some 15-day eggs, the larvae are surrounded by two shed cuticles. the outer first shed cuticle is composed of two layers. the inner second shed cuticle is much thicker than the outer one. the presence of both shed cuticles indicates that the larva has undergone two developmental stages in the maturing egg. ... | 1995 | 7657453 |
| cross-reactions of sera from toxascaris leonina and ascaris suum infected mice with toxocara canis, toxascaris leonina and ascaris suum antigens. | the elisa method using larval es products and homogenized toxocara canis, toxascaris leonina and ascaris suum adult worms extract, was used to determine the possible cross-reactions in balb/c and c57bl/10 mice inoculated with embryonated eggs or adult worms extract of t. leonina of t. leonina or a. suum in single and multiple doses. when we used sera of mice infected with embryonated eggs of t. leonina against different heterologous ag, no cross-reactions against t. canis es and a. suum es ag we ... | 1995 | 7657459 |
| the aba-1 allergen of the nematode ascaris suum: epitope stability, mass spectrometry, and n-terminal sequence comparison with its homologue in toxocara canis. | aba-1 is a major allergen of nematode parasites of the genus ascaris which includes the large roundworms of humans and pigs, a. lumbricoides and a. suum, respectively. the allergen was purified from a. suum by immunoaffinity chromatography for immunochemical examination. the ige antibody repertoire is under mhc control in infected rodents and the ige-binding epitopes were robust to treatment with heat or periodate, and electroblotting on nitrocellulose. this implies that the ige epitopes compris ... | 1993 | 7682160 |
| dirofilaria immitis: detection of parasite-specific antigen by monoclonal antibodies in glomerulonephritis in infected dogs. | for the identification of circulating parasite antigens associated with immune-complex glomerulonephritis in dogs infected with dirofilaria immitis, monoclonal antibodies (mabs) were generated against adult worms. a total of 11 mabs were selected for cloning because of their high productivity and their lack of cross-reactivity with toxocara canis in indirect immunofluorescence tests. the ability of mabs to detect circulating antigens was examined using an antigen-capture enzyme-linked immunosorb ... | 1993 | 7682327 |
| epidemiology of toxocara spp. in stray dogs and cats in dublin, ireland. | a survey was undertaken to study the epidemiology of toxocara spp. in 350 dogs and 181 cats. a prevalence of 82.6% was recorded for toxocara canis and 42% for t. cati. the distribution of parasite burdens in both dogs and cats was overdispersed. the highest parasite prevalence rates and burdens were found in hosts of 12 to 24 weeks of age. no toxocara parasites were found in cats between 0 to 4 weeks old. there was no significant difference in parasite prevalence between male and female dogs or ... | 1994 | 7706682 |
| larval distribution of toxocara canis in balb/c mice at nine weeks and one year post-inoculation. | the migratory route of toxocara canis in the mouse includes two phases: a hepato-pulmonary phase and a myotropic-neurotropic phase. a study was made of the migratory behaviour of larvae one year post-inoculation (p.i.) comparing the results to those obtained at the end of an initial experiment (day 63 p.i). the larval distribution per organ was already definitive at 9 weeks p.i. the total parasitic load showed a reduction when the experiment was prolonged for one year. | 1994 | 7706687 |
| [a case of toxocara canis infection]. | 1995 | 7722397 | |
| effect of various doses of infective toxocara canis and toxocara cati eggs on the humoral response and distribution of larvae in mice. | the effect of 5-2,500 infective toxocara canis and 5-1,000 t. cati eggs on the humoral immune response and on the distribution of larvae in the organism was studied in paratenic hosts--inbred c57bl6/j mice. with each dose of t. canis eggs the maximal antibody level was recorded on day 56 post infection and was followed by a moderate decline that lasted until day 154 of the experiment. a correlation between the antibody level and the egg count was observed only with the infective dose of 5-50 egg ... | 1995 | 7724509 |
| [eosinophilic meningo-encephalo-myelitis due to toxocara canis]. | a 21-year-old woman was admitted to our hospital because of frontal headache, low-grade fever and convulsion. the patient had long been in a close contact with a dog. neurologic examination revealed meningeal irritation signs and cerebellar ataxia. slight leukocytosis with an increased rate of eosinophils (23.2%) was present. a lumbar puncture yielded 330 leukocytes/microliters with 30% of eosinophils; protein, 55 mg/dl; and increased igg synthesis, 43.6 mg/day. the antibody titer against toxoca ... | 1994 | 7729097 |
| mechanisms of eosinophilia in balb/c-nu/+ and congenitally athymic balb/c-nu/nu mice infected with toxocara canis. | we studied the mechanism of eosinophilia in balb/c-nu/+ (nu/+) and balb/c-nu/nu (nu/nu) mice infected with toxocara canis. eosinophilia with two peaks on days 11 and 21 of infection was observed in infected nu/+ mice, and with a peak on day 11 in nu/nu mice. interleukin-5 (il-5) mrna was expressed on day 5 of infection in the lung and spleen of nu/+ mice and in the lung of nu/nu mice, but not in the spleen of nu/nu mice. large numbers of eosinophils and lymphocytes infiltrated the lung of both m ... | 1995 | 7751031 |
| toxocara canis adult worm antigen induces proliferative response of healthy human peripheral blood mononuclear cells. | the proliferative response of human peripheral blood mononuclear cells (pbmc) from healthy donors to toxocara canis adult worm antigens (tca) was examined. pbmc from all donors examined (n = 7) strongly responded to tca in a dose-dependent fashion after six days of culture, irrespective of their serological reactivity. in contrast, cord blood mononuclear cells did not react to tca. the proliferation of pbmc in response to tca was completely inhibited by anti-hla-dr antibody. purified cd4+ t cell ... | 1995 | 7761111 |
| [ocular toxocariasis or retinoblastoma?]. | seroprevalence studies in spain have shown that a high number of the population has been in contact with toxocara canis although no cases of ocular involvement by this helminth have been described. the clinical and age of presentation makes differential diagnosis with retinoblastoma necessary, which is at time difficult, although essential since the treatment and prognosis are very different. | 1995 | 7779878 |
| comparison of the efficacies of three heartworm preventives against experimentally induced infections with ancylostoma caninum and toxocara canis in pups. | forty 11- to 12-week-old helminth-naive beagles were categorized by sex and weight and randomly assigned to 4 treatment groups (group 1, ivermectin/pyrantel pamoate; group 2, milbemycin oxime; group 3, untreated control; group 4, diethylcarbamazine/oxibendazole). each pup was inoculated po with approximately 100 infective ancylostoma caninum larvae and 100 larvated toxocara canis eggs on day 0, and repeatedly at 7-day intervals thereafter until day 56. administration of anthelmintics also began ... | 1995 | 7782242 |
| devitalization of bacterial and parasitic germs in sewage sludge during aerobic digestion under laboratory conditions. | the survival of 8 bacterial species (pseudomonas sp., salmonella sp., enterobacteriae, streptococcus sp., escherichia coli) was detected in municipal sewage sludge up to 37 hours of mesophilic aerobic digestion under laboratory conditions. the model strain enterococcus faecium ccm 4231 survived almost twice as long as the above-mentioned isolates. similar findings, regarding the viability of the microorganisms studied, were also determined during thermophilic aerobic digestion of municipal sewag ... | 1995 | 7793018 |
| [effect of environmental conditions on parasitic infection of dogs]. | the following intestinal parasites: dipylidium caninum, taenia hydatigena, trichocephalus vulpis, ancylostoma caninum, uncinaria stenocephala, toxocara canis, toxascaris leonina, ascaris sp. have been found on the basis of coprological investigations of 120 dogs from the wrocłow shelter, 20 dogs from wrocłow flats and 20 dogs from rural area of kielce district. total extensity of infection of rural dogs was 100% and 40-48% in town. these differences, according to the authors, are connected with ... | 1994 | 7801643 |
| epidemiologic approach to human toxocariasis in western france. | toxocara canis is a common parasite in puppies. the danger to human health has not been properly established. we estimated the current incidence of this pathogen in two western districts of france, loire-atlantique and maine et loire. blood samples from 1836 eosino-philic patients were collected and tested by an enzyme-linked immunosorbent assay (elisa) excretory-secretory toxocara antigen test. we obtained positive results in 22% of the cases and highly positive results in 7%. the elisa data se ... | 1994 | 7809006 |
| preferential expression of cd30 by human cd4+ t cells producing th2-type cytokines. | a large panel of human cd4+ t helper (th) cell clones with established th1, th2, or th0 profiles of cytokine secretion were examined for the expression of cd30, a member of the tumor necrosis factor receptor superfamily. th1 clones expressed poor or no cd30 mrna, and showed low or undetectable expression of both membrane and soluble cd30 (scd30) protein, whereas th2 clones showed both cd30 mrna and membrane cd30 and released substantial amounts of scd30. th0 clones exhibited an intermediate patt ... | 1995 | 7821763 |
| chronic urticaria and toxocara canis. | 1995 | 7823695 | |
| prevalence of toxocara canis ova in public playgrounds in the dublin area of ireland. | a total of nine playground sites in dublin city and county were surveyed from which 228 samples were removed. of these samples, 15% were positive for toxocara canis ova and a mean egg density of 1.4 ova/100 g was calculated. two types of playground sites were identified and that the level of toxocaral contamination was found to be greater in 'neighbourhood playgrounds' than in 'adventure playgrounds'. there was no significant difference in the number of positive samples taken from sites both ins ... | 1994 | 7829844 |
| [acute eosinophilic pneumonia and the larva migrans syndrome: apropos of a case in an adult]. | toxocariasis is a frequent disease in children, but the severe clinical manifestations are rare in the literature (diffuse interstitial pneumonia with hypoxaemia and acute severe asthma). the diagnosis is made thanks to the reliability of serological techniques (the elisa test and using antigen excretion-secretion tests of the larvae of toxocara canis). the authors report a case of acute severe eosinophilic pneumonia whose outcome was rapidly favourable following steroid therapy; the existence o ... | 1994 | 7831510 |
| effect of immunomodulation on the course of experimental toxocariasis in mice. | immunosuppressed groups treated with cortisone showed fulmination of toxocara canis infection in terms of significant increase in brain parasitism, total larval count and significant decrease in the percentage reduction of the total count. suppression of the host inflammatory responses was detected in the liver, lungs, brain and muscles. accelerated transit of larvae through the liver was observed when cortisone was given before infection. whether bcg was given before or after infection, it show ... | 1994 | 7844434 |
| workshop summary: parasitic zoonoses--new issues. | 1994 | 7846860 | |
| [changes in the lungs in mice caused by migration of toxocara canis larvae]. | the influence of t. canis larvae migration on the lung tissue of paratenic host (inbred mice, strain c57bl6/j) was evaluated. first macroscopic manifestation was already observed on day 2 in the time of the highest larval recovery. larvae entering the lung tissue caused numerous small extravasations. their migration from the lungs was manifested from day 6 with an increase in the number and extent of extravasations. the lungs assumed tiger spot appearance (fig. 1). the larval recovery was decrea ... | 1994 | 7863576 |
| mr in toxocara canis myelopathy. | we present the case of a 23-year-old woman with cerebrospinal fluid eosinophilia and myelopathy caused by toxocara canis and describe the clinical and thoracic mr findings. an enhancing thoracic spinal cord lesion which was shown on mr resolved after an interval of 140 days with partial resolution of the patient's symptoms. | 1994 | 7863942 |
| mechanisms of eosinophilia in toxocara canis infected mice: in vitro production of interleukin 5 by lung cells of both normal and congenitally athymic nude mice. | mechanisms of eosinophilia were compared between in vitro bone marrow cell cultures of congenitally athymic (nu/nu) mice and their heterozygous littermates (nu/+). cultures of 5 x 10(4) bone marrow cells using interleukin 3 (il-3), il-5 and granulocyte-macrophage colony-stimulating factor showed that nu/nu and nu/+ mice mimicked each other in eosinophil production both before and after infection with toxocara canis. eosinophil differentiating activity (eda) was detected in media conditioned by s ... | 1993 | 7877846 |
| antibody to interleukin 5 prevents blood and tissue eosinophilia but not liver trapping in murine larval toxocariasis. | mice previously sensitized by infective-stage larvae of the canine nematode, toxocara canis, trap large numbers of challenge larvae within the liver; trapped larvae are found within eosinophilic granulomas. to investigate the role of eosinophils in this phenomenon we examined larval trapping in mice depleted of blood and tissue eosinophils by treatment with a monoclonal antibody (moab) (trfk-5) produced against recombinant murine interleukin 5 (rmil-5). control mice received either an isotype-ma ... | 1993 | 7877847 |
| toxocara-induced eosinophilic inflammation. airway function and effect of anti-il-5. | the immunoinflammatory response to parasitic nematode infections and allergic diseases have some similarities, the most profound being the increases in eosinophils and serum total ige concentration. whether parasitic infections stimulate or inhibit allergic asthma is a matter of debate. we investigated the effect of toxocara canis (t. canis) infection on airway function in balb/c mice at various days post-infection. within 24 h after infection, the trachea responded hyperreactive to carbachol st ... | 1995 | 7881685 |
| role of small mammals in the epidemiology of toxocariasis. | studies were conducted on the role of small mammals in maintaining toxocariasis foci in urban, rural and montane biotopes. the lowest relative density of small mammals was recorded in the urban locality and the highest in the rural and montane localities. anti-toxocara antibodies were most frequently detected in synanthropic and hemisynanthropic species mus musculus, apodemus agrarius and micromys minutus--32.0, 30.4 and 25.0%, respectively. the highest seropositivity was found in small mammals ... | 1995 | 7885737 |
| the behavior and pathogenicity of toxacara canis larvae in mice of different strains. | in the present study the behavior and pathogenicity of second-stage larvae of toxocara canis were examined in different mouse strains with special emphasis on the major histocompatibility complex (mhc). mice of the inbred strains balb, c3h, c57bl, and dba and the outbred strain nmri were infected orally with 1000 second-stage larvae of t. canis. the clinical behavior of the animals; the numbers of larvae detected in the liver, lungs, brain, and musculature; the hematological and serological para ... | 1994 | 7886040 |
| studies on the control of toxocara canis in breeding kennels. | the control of toxocara canis was investigated in naturally infected unweaned puppies. anthelmintic treatments were administered to three litters of pups at 2, 4 and 6 weeks of age. when either a new combination anthelmintic containing febantel, pyrantel embonate and praziquantel or fenbendazole was used, the faecal egg output over the first 7 weeks of life was reduced by more than 80% and worm burdens by over 90%. in contrast, piperazine adipate had no appreciable effect on t. canis egg output, ... | 1994 | 7886923 |
| [diagnosis and treatment of eye infections caused by the canine ascaris larva toxocara canis]. | in the years 1990-1993 the authors diagnosed and treated 48 children on account of uveitis probably caused by toxocara canis. this etiology was established in 43 cases based on the characteristic clinical picture and presence of antibodies as determined by the elisa test for toxocara in serum, anterior chamber fluid and vitreous. diagnostic punction of anterior chamber was done in 30 cases (in 18 titres were positive, in 7 higher than in serum), in 3 the level of antibodies were determined in vi ... | 1994 | 7897994 |
| toxocara canis (nematoda, ascarididae): ultrastructure of the rachis and the ovarian wall. | the oogonia and oocytes in the ovaries of toxocara canis are joined to a cytoplasmic process called the rachis. the rachis is a much branched cytoplasmic mass without cell components in the germinal zone. at the end of the germinal zone and in the growth zone the cytoplasmic mass is formed into a central axial cylinder, containing small dense granules, lipid drops and glycogen. throughout the growth zone shell granules similar to those present in the oocytes are also present in the rachis. anter ... | 1994 | 7927063 |
| [the helminth fauna of red foxes (vulpes vulpes linne 1758) in the administrative district of karlsruhe. 2. nematodes]. | between february 1989 and january 1990 a total of 801 foxes were examined for the presence of nematodes in the stomach and the small intestine and 835 foxes for the presence of trichinella spiralis larvae. the animals came from the german federal administration area of karlsruhe. the following nematodes in order of frequency were found: toxocara canis (30.2%), uncinaria stenocephala (24.3%), toxascaris leonina (2.0%) and ancyclostoma caninum (1.1%). the investigation of the muscles of all animal ... | 1994 | 7956813 |
| influence of soil texture in the recovery of toxocara canis eggs by a flotation method. | in epidemiological surveys, the evaluation of soil contamination by toxocara canis eggs requires a quick and easy method for the isolation of parasite eggs from soil samples. the efficiency of flotation methods is influenced by sample size, soil texture, degree of soil contamination, pretreatment, flotation solutions and time of flotation. this investigation was designed to evaluate the influence of soil texture in the recovery of t. canis eggs with the centrifugal flotation technique of dada (d ... | 1994 | 7975122 |
| efficacy of fenbendazole against giardiasis in dogs. | efficacy of fenbendazole at 2 dosages for treating naturally acquired giardiasis in dogs was assessed. giardia cysts were not detected in the feces of 6 of 6 group-1 dogs (as determined by use of the zinc sulfate concentration technique) after fenbendazole treatment (50 mg/kg of body weight, po, q 24 h, for 3 doses). cysts were not detected in the feces of 6 of 6 group-2 dogs after fenbendazole treatment (50 mg/kg of body weight, po, q 8 h, for 3 days). however, cysts were not detected in the fe ... | 1994 | 7978640 |
| toxocara canis and human health. | 1994 | 7980773 | |
| epidemiology of human toxocariasis in la réunion. | in la réunion island (indian ocean) a seroepidemiological survey for toxocariasis was carried out among 387 subjects over 15 years old by western blotting using toxocara canis excretory-secretory larval antigens; 92.8% of the sera were positive. statistical study, including logistic regression analysis, showed a significant correlation of western blot results with sex, age, and absence of water supply. the final logistic model demonstrated that only the last 2 factors were significant multiplica ... | 1994 | 7992328 |
| [frequency of finding helminths eggs in canine stool samples collected in public places in the la plata city, argentina]. | a study was carried out in order to determine the level of contamination with helminth eggs in different sectors of the city of la plata, argentina. a total of 351 fecal pools were collected from streets (328) and parks and public places (23) of this locality. of these fecal pools, 117 (33.3%) contained eggs of at least one helminth species. the overall frequencies found were: uncinaria sp. 16.0%, trichuris vulpis 9.7% and toxocara canis 10.5%. | 1993 | 7993539 |
| cloning and high level expression of gene encoding es antigen from trichinella spiralis muscle larvae. | the partial structure gene encoding es antigen derived from trichinella spiralis (tsp) muscle larvae was cloned, characterized, and expressed in e. coli. the target dna (0.7 kb) was directly obtained from the tsp total rna by using rna pcr technique. based on the analysis with the re digestion, the fragment was cloned into the fusion expression vector pex31c. it was shown that a kind of 37kda fusion protein was expressed in e. coli containing the recombinant plasmid by sds-page electrophoresis. ... | 1994 | 7993968 |
| dusn occurs in europe. | 1994 | 8008358 | |
| [rheumatologic aspects of toxocariasis (visceral larva migrans). apropos of 2 cases]. | visceral larva migrans is a human infection by the larvae of dog ascarids or, more rarely, ascarids of other animal species. it is endemic in france. two cases which respectively manifested as acute oligoarthritis and inflammatory myalgia with increased muscle enzyme levels are reported. manifestations of the minor forms of this infestation are reviewed. | 1993 | 8012340 |
| [how many patients with visceral toxocariasis in russia?]. | based on the results of numerous seroepidemiological surveys of inhabitants in russia using the toxocara/igg enzyme immune test system and supposing that extremely high antibody titers (1:6400 or higher) are an indicator of manifest visceral toxocariasis, the possible number of patients with this infection was estimated in the russian federation. the absolute number of the patients is roughly 550,000, the relative rate is 380 per 100,000 population. children aged 0-9 years were shown to prevail ... | 1994 | 8015514 |
| intestinal helminth parasite community in wolves (canis lupus) in italy. | from 1987 to 1993, 89 wolves (canis lupus) collected throughout the whole italian range were examined for intestinal helminth parasites. twelve species were found, including 5 nematodes (uncinaria stenocephala, toxocara canis, ancylostoma caninum, trichuris vulpis and toxascaris leonina) and 7 cestodes (echinococcus granulosus, taenia hydatigena, t. multiceps, t. pisiformis, t. ovis, mesocestoides lineatus and dipylidium caninum). no significant differences were detected between sexes. t. canis ... | 1993 | 8065823 |
| [preparation of membrane proteins of trichinella spiralis larva and application of them in detection with elisa]. | membrane proteins of muscle larva of trichinella spiralis (t.s) were isolated by using the non-ionic detergent triton x-114. at least fourteen components in the membrane proteins were separated with sds-page and then silver nitrate stain. the bands of them were located between 99-18kd mw level. the mw of chief bands were 94, 90, 47, 32 and 28kd. the sensitivity and specificity of these proteins were determined with elisa. they didn't cross react with sera of rabbits infected with toxocara canis ... | 1994 | 8070772 |
| infectivity of toxocara canis larvae from japanese quails in mice. | two hundred toxocara canis larvae derived from japanese quail liver were given orally to each of 50 8-week-old ddy mice and parasitism of the larvae was examined during 6 hr and 120 days after inoculation. although there were no clinical signs in infected mice, larvae were recovered from the liver (21.5 +/- 16.3 larvae), lung (5.1 +/- 6.0 larvae), kidney (0.7 +/- 1.1 larvae), small intestine (1.0 +/- 2.0 larvae), mesentery (1.6 +/- 3.1 larvae), and brain (7.8 +/- 6.8 larvae). | 1994 | 8075236 |
| [ascaridiasis zoonoses: visceral larva migrans syndromes]. | the syndrome of visceral larva migrans is a zoonotic disease due to the migration in human of nematodes larval, specially ascarid. since the larvae fail to complete their migrating cycle in humans, the diagnosis of toxocariasis infection remains only serologic. we have been able to demonstrate by the technique of agar diffusion and the western-blotting method that the etiology due to toxocara canis was twice as much frequent as the one due to toxocara cati in the syndrome of visceral and ocular ... | 1994 | 8076198 |
| experimental murine toxocariasis histopathological study of chronic renal infection, transplacental transmission and ultrastructural study of egg shell. | histopathological examination of kidney of swiss albino mice, 2 1/2 months after infection with toxocara canis eggs revealed various pictures of pathological affection. there was diffuse mesangioproliferative glomerulonephritis with mesangeal expansion of most of glomeruli. some glomeruli showed severe hyalinosis with marked adhesions to the bowman's capsule. the lumina of glomerular capillaries were markedly obliterated. there was also cystic dilatation of tubules with proteinaceous casts. the ... | 1994 | 8077752 |
| adult toxocara canis encephalitis. | a 48-year-old patient with toxocara canis infection developed severe ataxia, rigor and neuropsychological disturbances. an aetiology was proven by an indirect immunofluorescence test. ct and mri revealed both diffuse and circumscribed white matter lesions. angiography showed multiple occlusion of branches of the middle cerebral artery. anthelminthic treatment was beneficial in the initial stage of the disease, but had no effect on progression of cns symptoms. immunosuppressive therapy with predn ... | 1994 | 8126514 |
| presence of lipids in the secretory/excretory product from toxocara canis. | the presence of lipids in the secretory/excretory product obtained from toxocara canis has been demonstrated. the fatty acids found were mostly saturated, such as myristic (14:0), palmitic (16:0) and stearic (18:0). in addition, important quantities of oleic and linoleic acids (18:1 and 18:2) and cholesterol were detected. three more fatty acids appearing in low percentages are still to be identified. | 1993 | 8128580 |
| a seroepidemiological study of human toxocara infection in the slovak republic. | sera of 908 blood donors, average age 35 years, living in towns and villages of the slovak republic were tested for toxocara canis antibodies using an elisa-igg test. the seroprevalence in the healthy population was estimated at 13.65%. antibodies were predominantly demonstrated in the sera from persons living in rural communities (17.09%) compared to the sera investigated from urban communities (11.82%). women had a significantly higher seropositivity than men. the serological response in 2703 ... | 1993 | 8132974 |
| hepatic visceral larva migrans: evolution of the lesion, diagnosis, and role of high-dose albendazole therapy. | an unusual presentation of hepatic involvement of visceral larva migrans is described. a 45-yr-old male presented with fever, pain in the right upper quadrant, and persistent eosinophilia. ultrasound initially detected a solitary hypoechoic area in the right lobe of the liver which rapidly progressed to multiple lesions with peripheral hyperechoic lesions. aspiration from the lesion revealed charcot-leyden crystals and sheets of eosinophils. serology for toxocara canis was strongly positive. pro ... | 1994 | 8147371 |
| toxocara canis-induced murine pulmonary inflammation: analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid. | the pulmonary immuno-inflammatory reaction and its effect on microvascular integrity was studied in toxocara canis infected balb/c mice. the investigation aimed to compare changes in lung histology and composition of bronchoalveolar lavage fluid (balf) caused by t. canis infection with those described to occur in allergic asthma. groups of (non)-infected mice (1000 ova) were investigated until 90 days post infection (p.i.). migration of the larvae through the lungs was followed by a rapidly prog ... | 1994 | 8152829 |
| elisa seropositivity for toxocara canis antibodies in malaysia, 1989-1991. | the laboratory test results for visceral larva migrans (vlm) using elisa for toxocara canis antibodies employed by the institute for medical research, kuala lumpur, is described. a total of 331 serum samples received from hospitals and general practitioners all over malaysia were tested. the test utilises excretory-secretory antigens obtained from in vitro culture of second stage t. canis larvae. the overall seropositivity rate was 19.6%, the highest positive rate being in indians (35.5%), follo ... | 1993 | 8183143 |
| intestinal helminths of public health importance in dogs in nairobi. | in a survey of intestinal canine zoonotic helminths in nairobi, 156 dogs were autopsied. of these, 10% were infected with echinococcus granulosus, 88% with ancylostoma caninum, 45% with dipylidium caninum and 3% with toxocara canis. all the infected dogs with e. granulosus originated from around abottoirs in dagoretti. the risk of infection in man with hydatid disease is considered to be high around dagoretti and control measures are recommended. | 1993 | 8187655 |
| [utilization of elisa ige method in diagnosis of toxocariasis in humans]. | in order to improve the immunodiagnosis of toxocariasis, an immunoenzymatic assay (elisa) with excretory-secretory antigens from toxocara canis larvae was developed for the detection of specific immunoglobulin e. titers of ige were lower than those of igg in the same samples, however ige elisa appeared to be more specific. ige elisa might be an interesting complementary method in the diagnosis of toxocariasis. | 1993 | 8189832 |
| toxocara canis infection presenting as eosinophilic ascites and gastroenteritis. | eosinophilic ascites is rarely observed in clinical practice. it may be associated with the serosal type of eosinophilic gastroenteritis, abdominal lymphoma, hypereosinophilic syndrome, or peritoneal dialysis but is uncommonly related to parasitic infections. we report a case of a previously healthy young patient who developed diarrhea and exudative eosinophilic ascites. the final diagnosis was consistent with a parasitic infection due to toxocara canis, while the clinical and radiological findi ... | 1994 | 8200273 |
| parasitism of toxocara canis larvae in chickens inoculated with the ascarid eggs. | the distribution of t. canis larvae and pathological changes of the liver caused by them were studied in chickens inoculated orally with 1,500 embryonated eggs during 1 and 50 days after inoculation. the number of larvae recovered varied from 40 to 192 in the liver, 8 to 166 in the muscles, 0 to 4 in the heart, 0 to 2 in the spleen, 0 to 1 in the brain, respectively. small white foci were observed on the surface of the liver since 6 days after inoculation. histopathological examination of the li ... | 1994 | 8204739 |
| [toxocara ova in parks and sand-boxes in the city of utrecht]. | an investigation was carried out for the presence of toxocara spp. eggs in public parks and children's sand-boxes in the city of utrecht. the pollution of parks with the eggs of the dog's ascarid toxocara canis is comparable with reports from other european cities. the eggs of toxocara cati were found in small numbers only. interestingly there was no difference between parks with or without formal exclusion of dogs. most sand-boxes are polluted with the eggs of the ascarid of cats t. cati. incid ... | 1993 | 8211920 |
| nematocidal activity of turmeric: synergistic action of curcuminoids. | a new curcuminoid, cyclocurcumin (iv), was isolated from the nematocidally active fraction of turmeric, the rhizome of curcuma longa, together with three known curcuminoids, curcumin (i), demethoxycurcumin (ii) and bisdemethoxycurcumin (iii). the structure of iv was elucidated on the basis of spectral data and confirmed by the partial synthesis from curcumin (i). although the above curcuminoids were ineffective when they were applied independently, the nematocidal activity increased remarkably w ... | 1993 | 8221978 |
| eosinophilic meningoencephalitis due to toxocara canis. | 1993 | 8223820 | |
| the spectrum of ocular toxocariasis. | ocular toxocariasis is rare and therefore the spectrum of clinical disease is difficult to establish. we present a review of the clinical features and laboratory findings in a group of patients with positive toxocara serology and ocular toxocariasis. the clinical spectrum was diverse and milder disease was commoner than might be supposed from reviews of the literature. eosinophilia was unusual, but featured in two cases of unilateral pars planitis. | 1993 | 8224297 |
| zoonotic roundworm infections. | the larval stage of several animal parasites can infect humans and produce severe disease. visceral and ocular larval migrans caused by the common dog roundworm, toxocara canis, are two well-recognized clinical syndromes. with the wider availability of serodiagnostic tests for toxocaral infection, other syndromes characterized by neuropsychologic deficits, epilepsy, asthma, abdominal distress, and chronic allergy have been described. treatment with corticosteroids in conjunction with anthelminth ... | 1993 | 8254168 |
| [parasitological fecal studies of equids, dogs, cats and hedgehogs during the years 1984-1991]. | the results of the coproscopical examinations in horses, dogs, cats and hedgehogs between 1984 and 1991 are presented. in 9192 samples from horses 55.5% stages of strongylids, 4.0% of parascaris equorum, 2.2% of anoplocephalids, 1.6% strongyloides westeri, 0.7% of oxyuris equi, 0.6% of eimeria leuckarti, 0.2% of fasciola hepatica and 0.04% of dictyocaulus arnfieldi were found. in 48.0% of the 46 samples from donkeys eggs from strongylids were detected, in 17.4% larvae from dictyocaulus arnfieldi ... | 1993 | 8261912 |
| serosurvey of some major zoonotic infections in children and teenagers in bali, indonesia. | one hundred and ninety serum samples, mainly from children and teenagers, from northeast bali were tested for the presence of antibodies against five zoonotic agents: brucella abortus, coxiella burnetii, toxoplasma gondii, toxocara canis and trichinella spiralis. all children were negative for brucellosis and q fever. a high prevalence rate was found for toxocariasis (63.2%) and trichinosis (19.5%). antibody prevalence against t. gondii was found to be rather low (3.1%). to our knowledge, this i ... | 1993 | 8266236 |
| comparable seropositivity for ascariasis and toxocariasis in tropical slum children. | the seropositivities for infection by ascaris lumbricoides and toxocara canis were determined in children (1-15 years old) of a slum area of caracas, venezuela, and the levels that indicate the presence of active infection were defined. in children aged from 1 to 3 years, approximately 10% were positive for either parasite, and this figure increased to about 30% in 4- to 6-year-olds. for toxocariasis, the percentage of positivity remained at this level up to the age of 15 years. whilst the posit ... | 1993 | 8278336 |
| effects of pyrantel pamoate on adult and preadult toxocara canis worms: an electron microscope and autoradiography study. | adult as well as preadult toxocara canis isolated from the intestine of a beagle were incubated for 2, 4, and 14 h in medium containing either different concentrations of pyrantel pamoate (23.6, 236, and 2360 micrograms/ml medium) or tritiated pyrantel pamoate (2.36 micrograms/ml medium). these incubations were performed to study the effects of pyrantel pamoate on the morphology of the parasitic nematodes and to obtain information concerning the mode of uptake, the distribution, and the total am ... | 1993 | 8278339 |
| [the infection risk for dogs raised helminth-free in conventional conditions in an urban area]. | the present investigations were carried out to clarify whether or not and to what extent helminth-free raised dogs acquire patent and impatent helminth infections when exposed to an urban area contaminated with dog faeces. groups of each 3 bitches at an age of 3, 6 or 9 months were taken out to an urban area (with average dog density of 1.5 per ha) for 3 hours daily on 5 days per week for a period of 3 month. during the whole trial the bitches and puppies born during this period were maintained ... | 1993 | 8284959 |
| prevalence of toxocara eggs in sandpits in tokushima city and its outskirts. | to demonstrate the prevalence of toxocara eggs in sandpits in tokushima prefecture, japan, sand samples were examined. of 46 sandpits surveyed, 29 sandpits (63.3%) had toxocara eggs. sandpits in public parks and playgrounds in residential areas were more contaminated (87.5%) with the eggs than those in kindergartens, schools, and children's centers (36.4%). to examine the seasonal change in the contamination, sand samples obtained from five sandpits were examined monthly from may 1990 to april 1 ... | 1993 | 8286535 |
| ocular toxocariasis in children and youth. | the number of infections with larvae of the toxocara canis worm has been continuously increasing in the polish population, and the diagnosis and treatment of this disease is difficult. the authors describe 81 cases of eye infection in children and youth at the age of 3 to 18 years. the lesions in 94 eyes were observed for 0.5 to 11 years. in all patients the diagnosis was confirmed by elisa test. in the clinical picture various forms of uveitis and granuloma of the eye fundus were found. the tre ... | 1993 | 8299505 |
| toxocara canis: failure to find ige receptors (fc epsilon r) on eosinophils from infected mice suggests that murine eosinophils do not kill helminth larvae by an ige-dependent mechanism. | eosinophils obtained by bronchoalveolar lavage (bal) from the lungs of mice infected with toxocara canis were characterized by flow cytometry with respect to cytophilic antibodies and surface fc receptors. freshly harvested bal eosinophils were negative for sigm, siga, sige, and fc epsilon rii. these eosinophils were positive for sigg1 and fc gamma rii, although not all fc gamma riis contained bound ligand. culturing eosinophils for 24 or 48 hr with exogenous ige and/or il-4 did not induce ige b ... | 1994 | 8299761 |
| diagnosis of human toxocariasis by antigen capture enzyme linked immunosorbent assay. | to evaluate an antigen capture enzyme linked immunosorbent assay (elisa) which detects a carbohydrate epitope on the excretory-secretory (es) antigens of toxocara canis in clinical practice. | 1993 | 8331180 |
| changing chemosusceptibility in the second-stage larvae of toxocara canis by long-term incubation. | second-stage larvae of toxocara canis were maintained in vitro for one year. susceptibility of the larvae to drugs was evaluated by means of minimal larvicidal concentration (mlc) and larval bursting percentage. mlcs of citral and decanoic acid were almost constant throughout all stages of incubation. however, bursting percentage markedly varied within the first 20 weeks of incubation. therefore, while larvae are available for use in the mlc assay at any stage of incubation, those beyond the fir ... | 1993 | 8354860 |
| parasites of the arctic fox (alopex lagopus) in iceland. | forty-four of 50 arctic foxes (alopex lagopus) in iceland harbored 15 species of intestinal parasites, including protozoa: eimeria sp. or isospora sp. (in 4%); trematoda: cryptocotyle lingua (24%), plagiorchis elegans (4%), brachylaemus sp. (12%), tristriata sp. (10%), and spelotrema sp. (8%); cestoda: mesocestoides canislagopodis (72%), schistocephalus solidus (2%), and diphyllobothrium dendriticum (4%); nematoda: toxascaris leonina (50%), toxocara canis (2%), uncinaria stenocephala (4%), and e ... | 1993 | 8355346 |
| visceral and ocular larva migrans. | 1993 | 8356352 | |
| [toxocariasis. a rare disease or rarely recognized?]. | 1993 | 8362145 | |
| [toxocara canis associated with splenic rupture]. | 1993 | 8362150 | |
| [cerebral immune vasculitis as a complication of larva migrans infection caused by toxocara canis]. | 1993 | 8377723 | |
| epidemiology of toxocara canis in red foxes (vulpes vulpes) from urban areas of bristol. | a descriptive epidemiological survey was undertaken of the ascarid nematode toxocara canis in 521 red foxes (vulpes vulpes) during the period january 1986 to july 1990. age-prevalence and age-intensity profiles show that worm burdens are significantly higher in cubs than in subadult or adult foxes and higher in subadult than in adult foxes. seasonal variations in worm burdens occur, with the highest prevalences and intensities being found during the spring, when cubs are born, and in the summer ... | 1993 | 8414671 |
| isolation of feline eosinophils via peritoneal lavage. | fourteen cats were inoculated orally with 1 of 2 infective doses of toxocara canis to induce eosinophilia. cats were subsequently challenge exposed twice via intraperitoneal injection with 1 of 2 t canis antigen preparations. peritoneal lavage was performed 2 days after antigenic challenge exposure, and eosinophils in the peritoneal lavage fluid were quantified. none of the cats developed clinical signs of disease after infection. all cats developed peripheral eosinophilia after infection. signi ... | 1993 | 8430932 |
| "covert toxocariasis" in a child treated with low-dose diethylcarbamazine. | a girl aged 2.5 years with "covert toxocariasis" was treated with low-dose diethylcarbamazine because of supposed noticeable disseminated toxocara canis infection without ocular or visceral manifestations. there was marked blood and bone marrow eosinophilia, significant increased toxocara canis antibody (elisa) and immunoglobulins e, g and m, leucocytosis and an increased sedimentation rate. she had no geophagia, but often sucked small stones, probably contaminated with faeces from puppies. symp ... | 1993 | 8453208 |
| ocular toxocariasis in a patient with repeatedly negative elisa titre to toxocara canis. | 1993 | 8494866 | |
| efficacy of fenbendazole and piperazine against developing stages of toxocara and toxascaris in dogs. | in a series of controlled trials involving 59 naturally infected greyhounds, fenbendazole at a dose rate of 50 mg/kg/day for three consecutive days reduced the overall numbers of third and fourth stage toxocara canis by 94.0 per cent and third stage, fourth stage and immature adult stages of toxascaris leonina by 92.4 per cent. in contrast, piperazine at 100 mg/kg had little or no useful effect against the larval stages of t canis and t leonina and variable efficacy against immature adult t leon ... | 1993 | 8506598 |
| prevalence of toxocara eggs and number of faecal deposits from dogs and cats in sandpits of public parks in japan. | contamination of 13 sandpits in public parks in hyogo prefecture, japan, by toxocara eggs and animal faeces was studied. all 13 sandpits were contaminated with faeces. the mean number of faeces found in 1 m2 of the sandpits was 35, from which the number of faeces in each sandpit was estimated to be 261 to 2205. toxocara eggs were detected in 12 of the 13 sandpits, each examined 4-15 times; the overall prevalence was 92%. the eggs were not always distributed in the same pattern, but in general, e ... | 1993 | 8509622 |
| the art of parasite survival. | parasites develop and survive in an environment which is often hostile to them. when facing aggressive conditions parasites are able to use various and complex strategies. echinococcus granulosus, toxocara canis, pneumocystis carinii, entamoeba or toxoplasma gondii are able to seclude from the environment when stressed by surrounding (immunologic or non-immunologic) aggressive factors. specific antigens which exert a functional activity during a short period of time appear to be concealed from t ... | 1995 | 8520537 |
| a cdna encoding ribosomal protein l3 from the parasitic nematode toxocara canis. | a cdna encoding the ribosomal (r) protein l3 of the parasitic nematode toxocara canis was isolated from a library constructed from mrna of the infective larval stage. the encoded protein has a high degree of similarity to r-protein l3 from other organisms, including mammals, yeast, plants and bacteria. the mrna encoding r-protein l3 is derived from a single-copy gene, and experimental evidence would suggest that it contains the pan-nematode splice leader sequence at its 5' end and that the gene ... | 1995 | 8522183 |
| persistence of specific antibody response in different experimental infections of mice with toxocara canis larvae. | anti-toxocara antibody production and persistence were studied in experimental infections of balb/c mice, according to three different schedules: group i (gi)-25 mice infected with 200 t. canis eggs in a single dose; group ii (gii) 25 mice infected with 150 t. canis eggs given in three occasions, 50 in the 1st, 50 in the 5th and 50 in the 8th days; group iii (giii)-25 mice also infected with 150 t. canis eggs, in three 50 eggs portions given in the 1st, 14th and 28th days. a 15 mice control grou ... | 1995 | 8525261 |
| index of suspicion. case 1. toxocara canis and ascaris infection with lead poisoning]. | 1995 | 8539194 | |
| evaluation of mebendazole activity on experimental murine toxocariasis by immune complexes determination. | the mebendazole action on experimental murine toxocariasis, using different formulations and vehicles, was studied by means of the detection of antibodies and immune complexes by elisa. after inoculation with 1000 embryonated toxocara canis eggs, balb/c mice were submitted to the anthelmintic treatment as follows: group 1 (control without treatment); group 2 (mebendazole (mbz), lomper, steve laboratories, barcelona, spain, suspended in 1% sodium carboxymethylcellulose (cmc) at a dose of 100 mg/k ... | 1995 | 8546022 |
| specific igg1 and igg2 antibody responses of dogs to leishmania infantum and other parasites. | sera from dogs naturally infected with leishmania infantum were analysed for the igg subclass specificity of their antibody response by elisa. dogs infected with l. infantum produced both igg1 and igg2 antibodies with igg2 being associated with asymptomatic infections and igg1 being associated with disease (symptomatic dogs, non- or low-responsive to chemotherapy). the differential responses of igg1 and igg2 serum antibodies in asymptomatic and symptomatic dogs may indicate a dichotomous immune ... | 1995 | 8552413 |
| [identification of toxocara canis larvae in ocular granuloma]. | 1994 | 8560840 | |
| comparative sds-page protein patterns of four ascaridid nematodes. | in order to investigate the degree of homogeneity and heterogeneity of the ascaridid nematodes. toxascaris leonina, parascaris equorum, toxocara canis and t. vitulorum, protein extracts from adult worms of the four nematodes were resolved into a number of bands. comparative analysis of dominant bands showed that 13 bands were common among the four species, but certain unique bands were also found in each species including 4 in t. vitulorum, one in t. leonina, two in t. canis, while p. equorum sh ... | 1995 | 8586870 |
| incidence of toxoplasma and toxocara antibodies among out-patients in the ophthalmic research institute, egypt. | infection by toxoplasma gondii and toxocara canis is getting much important nowadays. both are soil transmitted infections. the present study was planned to detect the incidence of t. gondii and t. canis antibodies among 100 patients attending the outpatient clinics in research institutes of ophthalmology (rio), whose urine and stool were free from other parasitic stages. patients were classified into two groups, group i; (70 ocular cases) and group ii, (30 non-occular cases). control group (gro ... | 1995 | 8586877 |
| eosinophil chemotactic activity in bronchoalveolar lavage fluid obtained from toxocara canis-infected rats. | we examined eosinophil chemotactic activity (eca) in bronchoalveolar lavage fluid (balf) obtained from rats infected with toxocara canis. for 4 weeks after infection, the number of eosinophils was determined in peripheral blood and balf. eca was assayed using a microchemotaxis chamber. eosinophils in peripheral blood and balf increased markedly after infection, peaking at 12 days and 2 weeks, respectively. eca in balf also increased significantly and peaked 2 weeks after infection. partial chara ... | 1996 | 8605701 |
| an abundantly expressed mucin-like protein from toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins. | evasion of host immunity by toxocara canis infective larvae is mediated by the nematode surface coat, which is shed in response to binding by host antibody molecules or effector cells. the major constituent of the coat is the tes-120 glycoprotein series. we have isolated a 730-bp cdna from the gene encoding the apoprotein precursor of tes-120. the mrna is absent from t. canis adults but hyperabundant in larvae, making up approximately 10% of total mrna, and is trans-spliced with the nematode 5' ... | 1996 | 8643687 |
| pleural effusion and toxocariasis. | the case history is described of a woman who presented with bilateral pleural effusions caused by toxocara canis infestation. the condition responded rapidly to treatment. | 1996 | 8658358 |
| toxocara canis-induced airway eosinophilia and tracheal hyporeactivity in guinea pigs and mice. | guinea pigs and mice infected with the parasitic worms toxocara canis developed airway inflammation and tracheal hyporesponsiveness. preceding inflammatory cell infiltration a brief hyperreactive response occurred in guinea pigs to histaminergic receptor stimulation at 3 days post infection (p.i.) and in mice to acetylcholine receptor stimulation at 1 day p.i. few but large eosinophilic inflammatory foci developed in guinea pigs at 14 days p.i. mice demonstrated progressive multifocal inflammati ... | 1995 | 8666037 |