Publications

probing the potential of cnab-type domains for the design of tag/catcher systems.	building proteins into larger, post-translational assemblies in a defined and stable way is still a challenging task. a promising approach relies on so-called tag/catcher systems that are fused to the proteins of interest and allow a durable linkage via covalent intermolecular bonds. tags and catchers are generated by splitting protein domains that contain intramolecular isopeptide or ester bonds that form autocatalytically under physiological conditions. there are already numerous biotechnologi ...	2017	28654665
development of a multiplex pcr for identification of β-hemolytic streptococci relevant to human infections and serotype distribution of invasive streptococcus agalactiae in thailand.	a multiplex polymerase chain reaction (mpcr) was developed for simultaneous detection (single reaction) of genes specific to five frequent clinically relevant β-hemolytic streptococcal species: streptococcus pyogenes (spy1258), streptococcus agalactiae (cfb and cpn60), streptococcus dysgalactiae subsp. equisimilis (16s-23s intergenic spacer) , s. equi subsp. zooepidemicus (esaa and sord), and streptococcus anginosus group (moac). no cross-reaction was observed with other bacterial species. this ...	2017	28666619
streptococcal toxic-shock syndrome due to streptococcus dysgalactiae subspecies equisimilis in breast cancer-related lymphedema: a case report.	breast cancer-related lymphedema often causes cellulitis and is one of the most common complications after breast cancer surgery. streptococci are the major pathogens underlying such cellulitis. among the streptococci, the importance of the lancefield groups c and g is underappreciated; most cases involve streptococcus dysgalactiae subspecies equisimilis. despite having a relatively weak toxicity compared with group a streptococci, streptococcus dysgalactiae subspecies equisimilis is associated ...	2017	28705211
highly prevalent emmstg840.0 and emmstc839.0 types of erythromycin non-susceptible group g streptococcus isolated from bacteremia in southern taiwan.	group g streptococcus (ggs) infections in human have increased. treatment relied on antibiotic therapy, including erythromycin. however, information regarding the dominant strains and erythromycin susceptibility in ggs bacteremia is limited.	2017	28711431
multifocal septic arthritis, gluteal abscess and spondylodiscitis by streptococcus dysgalactiae subspecies equisimilis after an intramuscular injection.	we present the case of a 63-year-old man, admitted for hand cellulitis and acute kidney injury. a streptococcus dysgalactiae subsp equisimilis (sdse) was isolated in blood cultures and despite directed intravenous antibiotherapy, the patient evolved unfavourably, with dorsolumbar spondylodiscitis, multifocal septic arthritis and abscesses. ct also showed densification of the gluteal muscles, multiple air bubbles in the psoas, paraspinal muscles and spinal canal that were associated with an intra ...	2017	28724597
a 10-year observational study of streptococcus dysgalactiae bacteraemia in adults: frequent occurrence among female intravenous drug users.	beta-haemolytic streptococci of groups c and g have become increasingly recognized as causes of invasive human infections. we reviewed clinical and molecular characteristics of streptococcus dysgalactiae isolates that caused bacteraemia in adults from 2006 to 2015. among 67 episodes, skin and soft-tissue infections (43%) and emm types stg62647.0 (26%) were the most frequent clinical manifestation and emm type, respectively. nineteen (28%) episodes occurred in intravenous drug users (75% women). ...	2017	28750420
in vitro synergistic activities of cefazolin and nisin a against mastitis pathogens.	first-generation cephalosporins such as cefazolin (cez) have been widely used for mastitis treatment in dairy cattle. however, the use of antibiotics results in the presence of antibiotic residues in milk, which is used for human consumption. nisin a, a bacteriocin produced by lactococcus lactis, has been used as a broad-spectrum food preservative for over 50 years. therefore, a combination of cez and nisin a might provide an extended activity spectrum against mastitis pathogens and reduce the a ...	2017	28757508
within-herd prevalence thresholds for herd-level detection of mastitis pathogens using multiplex real-time pcr in bulk tank milk samples.	the objective of the study was to assess the value of quantitative multiplex real-time pcr examination of bulk tank milk samples for bovine mastitis pathogens as a tool for herd level diagnosis. using a logistic regression model, this study is aimed at calculating the threshold level of the apparent within-herd prevalence as determined by quarter milk sample cultivation of all lactating cows, thus allowing the detection of a herd positive for a specific pathogen within certain probability levels ...	2017	28780090
clinical and molecular characteristics of infective β-hemolytic streptococcal endocarditis.	streptococcus pyogenes (s. pyogenes) and streptococcus dysgalactiae subspecies equisimilis (sdse) cause considerable morbidity and mortality, and show similarities in disease manifestations and pathogenic mechanisms. their involvement in infective endocarditis, however, has not been well described. invasive s. pyogenes and sdse infections in health region bergen, norway, in the period 1999-2013 were reviewed, and sixteen cases of endocarditis were identified. the median duration of symptoms was ...	2017	28780243
emergence of a streptococcus dysgalactiae subspecies equisimilis stg62647-lineage associated with severe clinical manifestations.	increasing incidence rates of invasive streptococcus dysgalactiae subspecies equisimilis (sdse) infections have been reported worldwide, but the evolutionary mechanisms underlying this development remain elusive. through prospective surveillance of invasive sdse infections in western norway, we observed the emergence of a novel and virulent sdse genotype, stg62647. this emm-type, rarely encountered as a cause of invasive disease during 1999-2012, emerged in 2013 as the predominant sdse-genotype. ...	2017	28790435
cutaneous eruption associated with streptococcus dysgalactiae (group c streptococcus) bacteremia.		2017	28831413
use of maldi-tof mass spectrometry for the fast identification of gram-positive fish pathogens.	gram-positive cocci, such as streptococcus agalactiae, lactococcus garvieae, streptococcus iniae, and streptococcus dysgalactiae subsp. dysgalactiae, are found throughout the world, particularly in outbreaks in farmed fish, and are thus associated with high economic losses, especially in the cultivation of nile tilapia. the aim of this study was to evaluate the efficacy of matrix-assisted laser desorption ionization (maldi)-time of flight (tof) mass spectrometry (ms) as an alternative for the di ...	2017	28848512