Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| how accurate is a computerized surgical audit when resident medical staff collect the data? | since july 1988 all eight general surgeons at fremantle hospital have used a computer-based surgical audit and discharge system. at the time of writing (september 1991) 10,919 computer-generated discharge letters have been produced by the system. this paper describes the system and reports a series of quality control assessments carried out between 1 july 1988 and 30 june 1990 during which 30 pre-registration surgical residents completed 5,716 data collection forms. it was found that: (1) data c ... | 2006 | 1610325 |
| [fundus plication with or without proximal selective vagotomy?]. | the aim of this study was to determine the influence of proximal gastric vagotomy on the outcome after fundoplication. of 141 patients operated on for reflux disease between 1972 and 1988, 53 had fundoplication alone (group a) and 88 fundoplication combined with proximal gastric vagotomy (group b). the two groups were similar with regard to the severity of the reflux disease (esophagitis: a 69%, b 73%) but had a different incidence of concomitant ulcer disease (a 2%, b 55%). after a mean follow- ... | 2006 | 1621082 |
| persistence of vibrio vulnificus in tissues of gulf coast oysters, crassostrea virginica, exposed to seawater disinfected with uv light. | vibrio vulnificus is an estuarine bacterium which can cause opportunistic infections in humans consuming raw gulf coast oysters, crassostrea virginica. although v. vulnificus is known as a ubiquitous organism in the gulf of mexico, its ecological relationship with c. virginica has not been adequately defined. the objective of the present study was to test the hypothesis that v. vulnificus is a persistent microbial flora of oysters and unamenable to traditional methods of controlled purification, ... | 1992 | 1622218 |
| influence of a menhaden oil diet on cercarial penetration of schistosoma mansoni. | the ability of a menhaden oil (mo) diet to influence cercarial penetration into mouse tail skin was evaluated. male cd-1 mice 4-6 wk old (15.2 g average weight) were fed a 0, 10%, or 20% mo-supplemented diet for 2 wk. after this time mice were infected with either 65 +/- 3 or 145 +/- 3 [35s]methionine/cysteine-labeled cercariae for 1 hr by tail immersion. twenty-four hours and 7 days later groups of mice were killed and their tail skin removed and autoradiographed. at 24 hr postinfection, mice f ... | 1992 | 1635035 |
| total exenteration, two or one ostomy. | total exenterations require fecal and urinary diversions, necessitating ostomies in the anterior abdominal wall. this article was done to explore the possibility of extremely low anastomoses of the intestine to the anal stump, to reduce the number of ostomies to only one for the urinary diversion. although technically feasible, the long term follow-up evaluation of these patients resulted in us having reservations concerning function. | 2006 | 1636136 |
| possible role of plasminogen activator inhibitor 2 in the prevention of the metastasis of gastric cancer tissues. | the concentrations of urinary type plasminogen activator (u-pa), plasminogen activator inhibitor 1 (pai-1), and pai-2 were measured in gastric cancer tissues and adjacent healthy mucosal tissues. levels of u-pa, pai-1 and pai-2 were higher in cancer than in control tissues. pai-1 levels were higher together with the progression of cancer however there were no differences in u-pa or pai-2 levels. tumors with higher pai-1 and lower pai-2 levels tend to metastasize to remote lymph nodes. when the n ... | 2006 | 1636163 |
| serum autoantibodies in patients with alzheimer's disease and vascular dementia and in nondemented control subjects. | in this study we sought to evaluate the clinical significance of serum autoantibodies to dementing processes. | 2006 | 1636181 |
| [eye foreign bodies. patients should be sent to the eye clinic for treatment]. | 2006 | 1636298 | |
| a fatal case of vibrio vulnificus septicemia. | a fatal case of vibrio vulnificus septicemia in a 60 yr old man is described. this man displayed many of the classical features seen in fulminant infections with this organism. the epidemiology of v. vulnificus infections is discussed in this report. | 1992 | 1641257 |
| regulation of the mouse mammary tumor virus (mmtv) binding site in cultured mammary tissue. | the mouse mammary tumor virus (mmtv) initiates infection when the envelope protein, gp52, binds to a cell surface protein and triggers internalization. the hormonal regulation of this protein was studied both in vitro and in vivo. in mammary gland explant culture, levels of the mmtv binding protein were maintained only when prolactin was present in the medium. the further addition of progesterone induced levels to 164% of controls, while estradiol was without effect. these results were reproduce ... | 1991 | 1665450 |
| proceedings of the 3rd north sea conference on periodontology. maastricht, the netherlands, 16-19 may 1990. | 2006 | 1679767 | |
| cytolytic action of vibrio vulnificus haemolysin on mast cells from rat peritoneal cavity. | the mode of action of vibrio vulnificus haemolysin (vvh) on mast cells from the peritoneal cavity of the rat was examined. vvh induced histamine release, and damage to the mast cells, in a dose-dependent fashion. when 1 microgram of vvh was added to c. 10(5) mast cells at 37 degrees c, histamine release was observed after a lag period of 5-10 s, and was complete within 5 min. the action was temperature-dependent, and was not induced at 4 degrees c. disodium cromoglycate, a membrane stabiliser fo ... | 1990 | 1692881 |
| studies on the lipopolysaccharide of a virulent and an avirulent strain of vibrio vulnificus. | vibrio vulnificus is a marine bacterium associated with both primary septicemias and wound infections in humans. the lipopolysaccharides of a virulent and an avirulent strain of vibrio vulnificus were compared with respect to their chemical constituents and electrophoretic characteristics. 2-keto-3-deoxyoctonic acid, a normal constituent of the lipopolysaccharide of typical enterobacteriaceae, was not found in the lipopolysaccharide of either strain. hexadecenoate (c16:1) was the predominant fat ... | 1990 | 1693085 |
| developmental cycle-specific host-free rna synthesis in chlamydia spp. | the incorporation of radiolabeled gtp into rna in host-free chlamydia trachomatis serovar l2 organisms was investigated. the incorporation was partially inhibited by rifampin and dactinomycin and hydrolyzed by rnase. rna made by host-free chlamydiae consisted mainly of species of fewer than 800 bases in size, although 16s and 23s species were noted by agarose-gel electrophoresis. the hybridization of radiolabeled host-free rna to restriction fragments of the gene encoding the major outer membran ... | 1990 | 1698176 |
| fludarabine monophosphate for prolymphocytic leukaemia. | 2006 | 1698237 | |
| variants of mta, the mouse maternally transmitted antigen, determined by three alleles of the extrachromosomal gene mtf. | two new forms of mta, the maternally transmitted antigen of the mouse, were defined by cytotoxic t lymphocytes. one is found in laboratory mice carrying the beta allele of the maternally transmitted factor, mtf, which were previously thought to be mta-negative. the other is associated with a new allele, mtf gamma, and is found in wild mice from toulouse. like the common form of mta, determined by the extrachromosomal mtf alpha, the new forms are also dependent on the a allele of hmt, a chromosom ... | 1990 | 1698881 |
| phrenic motoneuron morphology in the neonatal rat. | the morphology of neonatal rat phrenic motoneurons was studied following retrograde labeling with horseradish peroxidase, which resulted in golgi-like fills of phrenic motoneuron somata and dendrites. at birth, these neurons have well-developed dendritic trees with many characteristics described for phrenic motoneurons in the adult rat. the dendrites form tightly fasciculated bundles that emerge from the phrenic nucleus primarily along four axes: ventromedial, ventrolateral, dorsolateral, and ro ... | 1991 | 1716267 |
| alpha-macroglobulin-like plasma inactivator for vibrio vulnificus metalloprotease. | the metalloprotease produced by vibrio vulnificus (vvp) is known to be quickly inactivated by plasma proteins which belong to the class of alpha-macroglobulins in vitro at a molar ratio of 1:1. but the in vivo potential of the inactivators has not been studied. macroalbumin (ma), a member of alpha-macroglobulins in guinea pig plasma, was found to inactivate vvp by means of physical entrapment in vitro. in vivo actions of vvp, permeability-enhancing and hemorrhagic actions, were greatly augmented ... | 1991 | 1723411 |
| a postero-anterior cephalometric evaluation of adult open bite subjects as related to normals. | reduced nasal airflow can be the result of enlarged adenoids, hypertrophic turbinates, severely deviated nasal septum, or even narrow nasal cavities. the question of whether the width of the nasal cavity may influence certain facial dimensions examined on the postero-anterior cephalometric x-ray was evaluated through the study of two different groups of subjects. possible intercorrelations between some other frontal dimensions were also examined in these subjects. the first group consisted of 15 ... | 2006 | 1748190 |
| identification of vibrio vulnificus o serovars with antilipopolysaccharide monoclonal antibody. | a serotyping scheme for vibrio vulnificus predicated on the detection of lipopolysaccharide (lps) antigens is proposed. the serovar o typing scheme used to type v. vulnificus employs polyclonal antisera raised in rabbits immunized with heat-killed whole-cell vaccines. polyclonal typing sera produced in this manner cross-react with heterologous strains. affinity purification of polyclonal antisera with lps affinity columns resolved some of these cross-reactions; however, affinity-purified polyclo ... | 1991 | 1761690 |
| acute myocardial infarction after blunt chest trauma in young people: need for prompt intervention. | we describe four cases of acute myocardial infarction in young patients, secondary to blunt chest trauma. one case was treated with intracoronary thrombolysis and angioplasty, two cases received systemic thrombolysis, and the last one did not have any reperfusion therapy. the coronary angiograms of the left anterior descending artery showed thrombosis in two cases, coronary dissection in one case, and no morphological lesions in the other. we encourage the early performance of angiographic studi ... | 2006 | 1764738 |
| the value of an expert system in performing clinical drug trials. | an expert system has been designed to assist the cardiologist in determining whether patients can be included in clinical trials. this system contains knowledge on inclusion and exclusion criteria for six drug trials, and has been validated in 100 randomly selected patients. in 97 cases, the expert system and the cardiologist made an identical classification; in the remaining three cases, the patient was incorrectly classified by the physician. the system will also optimize the order in which qu ... | 2006 | 1764928 |
| formation of nonculturable vibrio vulnificus cells and its relationship to the starvation state. | entry into the viable but nonculturable state by the human bacterial pathogen vibrio vulnificus in artificial seawater microcosms was studied. in contrast to the long-term culturability exhibited by cells incubated under these starvation conditions at room temperature, cells exposed to a temperature downshift to 5 degrees c exhibited an immediate decrease in culturability. cells incubated at low temperature exhibited a morphological change from rods to cocci but demonstrated no reductive divisio ... | 1991 | 1768138 |
| use of the polymerase chain reaction in detection of culturable and nonculturable vibrio vulnificus cells. | vibrio vulnificus is a human pathogen associated with consumption of raw oysters. during the colder months the organism apparently enters a viable but nonculturable state and thus cannot be cultured by ordinary bacteriological methods. for this reason, another means of detecting this bacterium is necessary. in the present study we utilized the polymerase chain reaction (pcr) to detect v. vulnificus dna, thus eliminating the problem of nonculturability. dna from both culturable and nonculturable ... | 1991 | 1768140 |
| analysis of high psa n-cam expression during mammalian spinal cord and peripheral nervous system development. | using a monoclonal antibody that recognizes specifically a high polysialylated form of n-cam (high psa n-cam), the temporal and spatial expression of this molecule was studied in developing spinal cord and neural crest derivatives of mouse truncal region. temporal expression was analyzed on immunoblots of spinal cord and dorsal root ganglia (drgs) extracts microdissected at different developmental stages. analysis of the ratio of high psa n-cam to total n-cam indicated that sialylation and desia ... | 1991 | 1769342 |
| [transient polyuria in pregnancy in diabetes insipidus and gestational diabetes]. | two pregnant women developed overt polyuria (up to 11 l/day) and polydipsia during their second and third trimesters of pregnancy. in one patient hydronephrosis was present. both patients suffered from mild gestational diabetes mellitus. plasma sodium was 145 and 162 mmol/l. polyuria and urinary hypo-osmolality responded well to desmopressin acetate. after delivery, polyuria and polydipsia disappeared in one patient and significantly improved in the other. infusion of hypertonic saline one and t ... | 2007 | 1770904 |
| vibrio vulnificus. hazard on the half shell. | vibrio vulnificus is an extremely invasive gram-negative bacillus that causes bacteremia and shock. it should be suspected in any patient who is immunocompromised or has liver disease or hemochromatosis. reduced gastric acidity may also increase the risk of infection if a patient presents with a history of ingesting raw shellfish (especially oysters) or trauma in brackish waters and skin lesions. patients most commonly present with one of three clinical syndromes: primary septicemia, wound infec ... | 1991 | 1771878 |
| a lethal leviathan--vibrio vulnificus. | 1991 | 1771890 | |
| vibrio vulnificus peritonitis. a unique case. | louisiana is justifiably famous for the seafood harvested from its coastal waters. unfortunately, undesirables accompany this harvest. the author presents a case of peritonitis due to vibrio vulnificus which followed ingestion of raw oysters. | 1991 | 1779190 |
| physiological effects of the lipopolysaccharide of vibrio vulnificus on mice and rats. | vibrio vulnificus is a pathogenic, marine, gram-negative bacterium which commonly enters and infects humans via open wounds or the ingestion of raw seafood. the lipopolysaccharide (lps) of v. vulnificus has recently been characterized, but the biological activity of this putative endotoxin is unknown. three treatment groups were used to test its activity: saline (negative control), the lps of salmonella typhimurium (a known endotoxin), and the lps of v. vulnificus. whereas, intravenous injection ... | 1991 | 1779875 |
| illumination and errors in dispensing. | the relationship between the level of illumination and the prescription-dispensing error rate in a high-volume army outpatient pharmacy was investigated. the prescription error rate was determined by direct, undisguised observation and retrospective prescription review under three levels of illumination (45, 102, and 146 foot-candles) during 21 consecutive weekdays. illumination was controlled in the prescription-checking area of the pharmacy by using additional fluorescent lamps and filters. th ... | 2007 | 1781468 |
| legal considerations in international eye banking. | 2005 | 1782162 | |
| project orbis: cornea transplantation in the 90s. | 2005 | 1782178 | |
| [biological characteristics of cultured papilla cells--localization of androgen receptors and chemotactic factor(s) for epithelial cells]. | we have reported that cultured papilla cells (pcs) grown by isolation and cultivation of human hair papillae show some biological characteristics. in the present report, some important biological characteristics of pcs are showed. 1) localization of androgen receptors on pcs localization of androgen binding protein in pcs was examined. cytochemical staining of pcs using dht-peroxidase conjugate gave positive reactions in the niclei of pcs originating from scalp and axilla-dermal papillae. these ... | 1991 | 1782180 |
| the assessment of antero-posterior dental base relationships. | the reliability and validity of four methods of assessing skeletal pattern (reidel's method, eastman correction, ballard's method, and 'wits' analysis) from cephalometric tracings have been examined, and the levels of agreement between them investigated. the possibility of the y-axis length and sn-y-axis angle having a bearing on the skeletal pattern was also examined. strong correlation was found between the four methods considered. ballard's method correlated very closely with reidel's method, ... | 2005 | 1782187 |
| extensive cellulitis with septic shock caused by vibrio vulnificus infection--a case report with review of literature. | 1991 | 1791352 | |
| lauryl sulphate haemoglobin: a non-hazardous substitute for hicn in haemoglobinometry. | the haemiglobincyanide (hicn) method for measuring haemoglobin is used extensively worldwide; its advantage is the ready availability of a stable and internationally accepted reference standard/calibrator. however, its use may create a problem, especially in automated analysers, as the waste disposal of large volumes of reagent containing cyanide may constitute a potential toxic hazard. as an alternative, conversion of haemoglobin to a sulphate derivative by nontoxic sodium lauryl sulphate has b ... | 2007 | 1794230 |
| a role for nmr in alcoholism? | 2006 | 1796991 | |
| a role for nmr in alcoholism? | 2006 | 1796991 | |
| unconjugated and conjugated bilirubin pigments during perinatal development. iii. studies on serum of breast-fed and formula-fed neonates. | the process of conjugation and secretion of bilirubin was studied in a group of healthy, full-term, exclusively breast-fed newborns and a control group of exclusively formula-fed infants by means of a reverse-phase high-performance liquid chromatographic analysis of bilirubins present in serum. the serum concentrations of unconjugated bilirubin, esterified bilirubin, and the proportion of diesterified bilirubin (as percent of esterified bilirubin) were not significantly different in breast- and ... | 1991 | 1797114 |
| unconjugated and conjugated bilirubin pigments during perinatal development. iii. studies on serum of breast-fed and formula-fed neonates. | the process of conjugation and secretion of bilirubin was studied in a group of healthy, full-term, exclusively breast-fed newborns and a control group of exclusively formula-fed infants by means of a reverse-phase high-performance liquid chromatographic analysis of bilirubins present in serum. the serum concentrations of unconjugated bilirubin, esterified bilirubin, and the proportion of diesterified bilirubin (as percent of esterified bilirubin) were not significantly different in breast- and ... | 1991 | 1797114 |
| transcatheter management of pseudoaneurysms complicating pancreatitis. | hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ... | 2006 | 1797219 |
| transcatheter management of pseudoaneurysms complicating pancreatitis. | hemorrhage from rupture of an arterial pseudoaneurysm is a potentially fatal complication of pancreatitis. seventeen patients underwent transcatheter embolization of 23 arteries for the treatment of 20 arterial pseudoaneurysms secondary to pancreatitis. their records were reviewed retrospectively to evaluate the clinical benefit of transcatheter therapy. at presentation, 15 of the 17 patients had gastrointestinal, intrasplenic, retroperitoneal, intraperitoneal, or postoperative wound bleeding. t ... | 2006 | 1797219 |
| inbreeding in saguenay-lac-st-jean (quebec, canada): a study of catholic church dispensations 1842-1971. | saguenay-lac-st-jean (slsj) is a rather geographically isolated region of quebec which shows a high occurrence of hereditary disorders. it has been suggested that high inbreeding might explain this situation. we studied the inbreeding in the slsj region by 10-year periods from 1842 till 1971 using the catholic church dispensations. the values of the mean inbreeding coefficient were found to be low during the whole period, reaching a peak of 22.94 x 10(-4) during the period 1902-1911. the values ... | 2007 | 1797631 |
| occult rupture of spleen. | 2007 | 1800517 | |
| a general software package for the handling of medical images. | pics (portable imaging computer software), is a software system designed for handling and processing a variety of types of medical image. it has been designed to satisfy the following criteria: (a) the software should be portable between different items of hardware with minimal alteration; (b) there should be a simple operator interface to enable use by inexperienced users, while avoiding the need for experienced users to be directed through tedious menu trees; (c) the programming environment sh ... | 2006 | 1800747 |
| a general software package for the handling of medical images. | pics (portable imaging computer software), is a software system designed for handling and processing a variety of types of medical image. it has been designed to satisfy the following criteria: (a) the software should be portable between different items of hardware with minimal alteration; (b) there should be a simple operator interface to enable use by inexperienced users, while avoiding the need for experienced users to be directed through tedious menu trees; (c) the programming environment sh ... | 2006 | 1800747 |
| a primary demyelinating disorder of young cattle. | the clinical signs and neuropathological changes are described in six limousin x calves that, at about one month after birth, showed signs of blindness, nystagmus, rotation of the eyes, opisthotonos, hyperprotraction of the forelegs and, in one case, apparent seizures. pathologically there was necrosis of the optic chiasma and focal areas of myelin sheath vacuolation or demyelination in certain areas of the brain, especially in the cerebellar peduncles. in one animal, kept alive for 7 months, th ... | 1991 | 1800911 |
| surgical treatment of morbid obesity. a survey of overall outcome 1968-1989. | this survey evaluates benefits and costs from a policy of employing surgical treatment in selected cases of morbid obesity. between 1968 and 1978, we used end-to-side jejunoileal bypass. despite many satisfied patients, complications were frequent and severe. for the next decade, we employed various types of gastric surgery. we eventually assessed a gastric balloon, but without success. median duration of follow-up was 132 months in 145 patients with jejunoileostomy, 103 months in seven gastric ... | 2006 | 1802626 |
| surgical treatment of morbid obesity. a survey of overall outcome 1968-1989. | this survey evaluates benefits and costs from a policy of employing surgical treatment in selected cases of morbid obesity. between 1968 and 1978, we used end-to-side jejunoileal bypass. despite many satisfied patients, complications were frequent and severe. for the next decade, we employed various types of gastric surgery. we eventually assessed a gastric balloon, but without success. median duration of follow-up was 132 months in 145 patients with jejunoileostomy, 103 months in seven gastric ... | 2006 | 1802626 |
| acute intoxication as a cause of wild bird mortality in the netherlands from 1975-1989. | 2007 | 1805755 | |
| familial predisposition for herniation of a lumbar disc in patients who are less than twenty-one years old. | the parents of sixty-three patients who were less than twenty-one years old and who had operatively confirmed herniation of a lumbar disc were interviewed regarding a history of sever back pain, sciatica, and herniated disc, to determine whether aggregation of herniation of a lumbar disc occurs in families of patients in this young age-group. the parents of sixty-three additional patients who had a non-spinal orthopaedic diagnosis (control group) were matched for age and sex with the study group ... | 2007 | 1824705 |
| sensitivity to chromium-containing automobile parts. | 2006 | 1828411 | |
| sensitivity to chromium-containing automobile parts. | 2006 | 1828411 | |
| the use of potassium-titanyl-phosphate laser for laparoscopic removal of ovarian endometrioma. | from january 1989 through january 1990, 31 patients thought to have ovarian endometrioma at ultrasonography were treated by operative laparoscopy and potassium-titanyl-phosphate laser. the endometriomas ranged from 2 to 9.2 cm in diameter by preoperative transvaginal ultrasonography. the operative procedure used was a three-puncture technique with a 600 micron fiber attached to a potassium-titanyl-phosphate laser. the power setting was 10 w with a continuous pulse. in all cases endometriomas wer ... | 2006 | 1828651 |
| the use of potassium-titanyl-phosphate laser for laparoscopic removal of ovarian endometrioma. | from january 1989 through january 1990, 31 patients thought to have ovarian endometrioma at ultrasonography were treated by operative laparoscopy and potassium-titanyl-phosphate laser. the endometriomas ranged from 2 to 9.2 cm in diameter by preoperative transvaginal ultrasonography. the operative procedure used was a three-puncture technique with a 600 micron fiber attached to a potassium-titanyl-phosphate laser. the power setting was 10 w with a continuous pulse. in all cases endometriomas wer ... | 2006 | 1828651 |
| issues with radiation therapy article. | 2006 | 1828682 | |
| issues with radiation therapy article. | 2006 | 1828682 | |
| structure of the rabbit phospholamban gene, cloning of the human cdna, and assignment of the gene to human chromosome 6. | we have isolated and characterized genomic dna clones encoding rabbit phospholamban. only a single gene for phospholamban was detected in the rabbit genome. the phospholamban gene of 13.2 kilobases contains only one 10.5-kilobase intron, which separates exonic sequences located in the 5'-untranslated region. two potential transcription initiation sites were mapped to 335 and 185 nucleotides upstream from the translation initiation site in the mrna or 239 and 89 nucleotides upstream from the exon ... | 1991 | 1828805 |
| complexity and sequence identification of 24 rat v beta genes. | twenty-four tcr v beta genes were cloned by anchored pcr from the lewis rat strain and identified by nucleotide and amino acid sequence comparisons to known mouse v beta genes. rat v beta genes exist in 17 single-member and 3 multimember subfamilies and exhibit 86 to 94 and 72 to 92% nucleotide and amino acid sequence similarities, respectively, to their mouse counterparts. a single rat gene, designated v beta 20, having no previously known mouse counterpart was identified; a closely related gen ... | 1991 | 1828824 |
| aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage. | cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ... | 2006 | 1828960 |
| aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage. | cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ... | 2006 | 1828960 |
| purified protein derivative of mycobacterium tuberculosis and excretory-secretory antigen(s) of toxocara canis expand in vitro human t cells with stable and opposite (type 1 t helper or type 2 t helper) profile of cytokine production. | a large series of t cell clones (tcc) specific for purified protein derivative (ppd) of mycobacterium tuberculosis (total 60) or toxocara canis excretory/secretory (tes) antigen (total 69) were established from the peripheral blood of two healthy individuals and analyzed for their profile of cytokine production in response to stimulation with either the specific antigen or the polyclonal activator phorbol myristate acetate plus anti-cd3 antibody. under both these experimental conditions, the gre ... | 1991 | 1829097 |
| the extracellular cytolysin of vibrio vulnificus: inactivation and relationship to virulence in mice. | the ca. 51-kda extracellular cytolysin of vibrio vulnificus has been proposed as a virulence factor. we inactivated the structural gene for cytolysin in fully virulent, clinical v. vulnificus strains by both transposon mutagenesis and marker exchange techniques. inactivation of the cytolysin did not affect virulence in our mouse models. the 50% lethal dose of cytolysin-negative strains was comparable to that of the cytolysin-positive parent strains after intraperitoneal inoculation with and with ... | 1991 | 1846124 |
| growth arrest induced by transforming growth factor beta 1 is accompanied by protein phosphatase activation in human keratinocytes. | protein phosphorylation and dephosphorylation are involved in regulation of cell growth. we tested the hypothesis that the growth inhibitory effect of transforming growth factor beta 1 (tgf-beta 1) involves activation of protein phosphatases. exposure of human keratinocytes in culture to 400 pm tgf-beta 1 for 48 h led to 80% inhibition of dna synthesis as measured by nuclear labeling. incubation of cultured keratinocytes with 400 pm tgf-beta 1 rapidly activated (within 30 min) protein serine/thr ... | 1991 | 1847373 |
| absence of na+,k(+)-atpase regulation of endosomal acidification in k562 erythroleukemia cells. analysis via inhibition of transferrin recycling by low temperatures. | transferrin (tf) acidification has been shown to be limited to ph 6 in murine balb/c 3t3 fibroblasts, human a549 epidermoid carcinoma cells, and chinese hamster ovary cells and is followed by alkalinization during recycling. in contrast, tf acidification in the human erythroleukemic cell line k562 proceeds to below ph 5.5, and alkalinization of internal tf during recycling is not observed. to explore the regulation of endosomal ph in k562 cells, we determined whether the existence of an early en ... | 1991 | 1847374 |
| cyclic amp-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase d activation. | agents which elevate cellular camp (prostaglandin e2, theophylline, and forskolin) or mimic camp action (dibutyryl camp) are known to inhibit human neutrophil activation (superoxide generation and secretion) by receptor-linked agonists such as formyl-methionyl-leucyl-phenylalanine (fmlp). herein, we show that these agents also markedly inhibit fmlp-stimulated diradylglycerol generation (assayed by mass methods). the magnitude of inhibition correlated with the ability of a given agent or combinat ... | 1991 | 1847376 |
| quantitation of hormone replacement induced withdrawal bleeds. | 2007 | 1847822 | |
| regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action. | the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ... | 2007 | 1852316 |
| response by dr. alden n. haffner upon receipt of the koch memorial medal 1990. | 2007 | 1852404 | |
| development of circadian sleep-wake rhythms in preterm and full-term infants. | we have compared the roles of neurologic maturity and environmental time cues in the development of the entrained circadian sleep-wake rhythm in the preterm and term human infant. the preterm infants (n = 19) spent some time after birth in a hospital nursery with no environmental time cues, whereas the term infants (n = 22) were exposed from birth to a cyclical light and dark environment with one major caregiver. the circadian sleep-wake rhythm in the preterm infants entrained after a similar ti ... | 1991 | 1852533 |
| signal transduction mechanism of interleukin 6 in cultured rat mesangial cells. | interleukin 6 (il-6) is one of the potent autocrine growth factors for mesangial cells. we investigated the signal transduction mechanism of il-6 in cultured rat mesangial cells. il-6 induced a transient increase of inositol 1,4,5-trisphosphate (ins 1,4,5-p3) followed by a transient and sustained increase of intracellular calcium concentration, suggesting that il-6 stimulates phosphoinositide turnover. il-6 also stimulated prostaglandin e2 (pge2) production. the il-6-concentration dependency in ... | 1991 | 1855592 |
| [lipid metabolism disorders: diagnosis and treatment. 4: drug therapy and dietary recommendations. national cholesterin-initiative]. | 2006 | 1855762 | |
| [lipid metabolism disorders: diagnosis and treatment. 4: drug therapy and dietary recommendations. national cholesterin-initiative]. | 2006 | 1855762 | |
| [microbial spectrum and microbiological diagnosis of infectious endocarditis]. | still streptococci play the most important role as causatives of infective endocarditis. as change in composition of patient groups has taken place gradually pathogens like staphylococcus epidermidis, enterococci, gram-negative rods and candida species become more and more important now. providing high-level accuracy if applied according to current rules blood culture is yet the basis for endocarditis caused by popular bacterial pathogens. if infection due to candida species is suspected additio ... | 1991 | 1855807 |
| in vitro effect of phyllanthus amarus on hepatitis b virus. | to evaluate the effects of p. amarus on hepatitis b virus (hbv) antigens and hbv-dna, initial ethanolic extract and subsequent fractions of the plants were prepared. the whole plant material was dried, powdered and extracted with alcohol and subsequently fractionated in hexane, chloroform, butanol and finally in water. all the material were tested for in vitro effects on hbsag, hbeag and hbv-dna in serum samples positive for hbv antigens followed by the screening of respective antigens by elisa. ... | 1991 | 1855821 |
| resuscitation of vibrio vulnificus from the viable but nonculturable state. | stationary-phase-grown cells of the estuarine bacterium vibrio vulnificus became nonculturable in nutrient-limited artificial seawater microcosms after 27 days at 5 degrees c. when the nonculturable cells were subjected to temperature upshift by being placed at room temperature, the original bacterial numbers were detectable by plate counts after 3 days, with a corresponding increase in the direct viable counts from 3% to over 80% of the total cell count. no increase in the total cell count was ... | 1991 | 1860818 |
| vibrio vulnificus sepsis presenting as leg pain and lower extremity rash. | 1991 | 1863312 | |
| [atypical and combined forms of infectious-allergic polyneuropathies]. | 2007 | 1865642 | |
| hemochromatosis, iron and septicemia caused by vibrio vulnificus. | vibrio vulnificus is killed by normal human blood but grows rapidly in blood from patients with hemochromatosis. it also grows in normal blood if the saturation of the transferrin is increased or if hematin, which contains iron, is added. it is suggested that the increased availability of iron in the blood of patients with chronic iron overload is responsible for their enhanced susceptibility to infection with v vulnificus. | 1991 | 1872665 |
| functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-c3. | we have cloned a rat cdna encoding furin which is structurally related to yeast kex2 protease. products of 88 and 94 kda were obtained by in vitro transcription/translation of the cdna in the absence and presence of microsomes. when the cdna was transfected into cos-1 cells, furin was expressed as a major glycosylated form of 94 kda, accompanied by a minor proteolytic form of 86 kda, and found to be localized in the golgi complex. proalbumin and complement pro-c3 are intracellularly processed in ... | 1991 | 1885622 |
| discordant expression of tuberous sclerosis in monozygotic twins. | a set of 20-year-old female japanese twins, most probably monozygotic, had clinical evidence of tuberous sclerosis (ts). they were discordant for symptoms. one of the twins exhibited facial red-brown papules (adenoma sebaceum), a dorsal shagreen patch, intracerebral calcifications, angiomyolipoma in the right kidney, and hypopigmented macules; the other had only a few hypopigmented macules. modification of ts gene expression by the effects of environmental (extrinsic) factors is suggested. | 2007 | 1885853 |
| pet in generalized anxiety disorder. | positron emission tomography (pet) measurements of cerebral glucose use were made in 18 patients with generalized anxiety disorder (gad) during a passive viewing task off medication, and an active vigilance viewing task before and after medication or placebo treatment. in the passive viewing task, patients with gad were compared with 15 normal controls. a significant difference in pattern of absolute brain metabolism was found. patients showed lower absolute metabolic rates in basal ganglia and ... | 2007 | 1888800 |
| calcium regulation of the human pmn cytosolic 15-lipoxygenase. | addition of tracer (pg) amounts of [3h]arachidonic acid to the 120,000 x g cytosolic fraction of human polymorphonuclear leukocytes (pmns) produced [3h]-15-hete, the product of the 15-lipoxygenase, as the major metabolite. in the presence of nanomolar and low micromolar amounts of calcium, [3h]-15-hete formation was increased as much as 15-fold which corresponded to 17% conversion of added substrate. this enhancement of the cytosolic 15-lipoxygenase activity, which was reversible by egta, was in ... | 1991 | 1892881 |
| [vibrio vulnificus]. | a patient sustained a knife wound while cleaning eels and subsequently severe wound infection developed. vibrio vulnificus was isolated from the wound and, on the basis of this, the main features of the epidemiology of the bacteria and the typical clinical pictures are reviewed. | 1991 | 1897050 |
| failure of oocyte retrieval during in vitro fertilization: a sporadic event rather than a syndrome. | failure to retrieve oocytes during in vitro fertilization (ivf) treatment was recently referred to as the "empty follicle syndrome." data on the possible repetitiveness of this during previous or subsequent ivf attempts is lacking, which limits the understanding of its significance to the involved patients. of 26 patients who had cycles during which no oocytes were retrieved, 10 were pregnant in the past and 20 had at least one other ivf cycle that yielded oocytes. there was no difference in the ... | 2007 | 1899395 |
| purification and properties of a neurotensin-degrading endopeptidase from pig brain. | neurotensin (nt) endopeptidase (ec 3.4.24.16) has been purified about 800-fold from pig brain by four sequential chromatographic steps depending on ion-exchange and hydrophobic interactions. two types of preparation were studied: one from a triton x-100-solubilized membrane fraction, and the other from the soluble fraction containing 90% or more of the total activity in the homogenate. nt endopeptidase activity was monitored by high-precision liquid chromatography of the two peptide products, ch ... | 1991 | 1905921 |
| control of enterococcus faecalis sex pheromone cad1 elaboration: effects of culture aeration and pad1 plasmid-encoded determinants. | aeration of plasmid-free enterococcus faecalis strains resulted in an 8- to 16-fold decrease in sex pheromone cad1 activity in culture filtrates. levels of two unrelated pheromones, cpd1 and cam373, were unaffected by culture aeration. aeration also resulted in a decrease in the expression of conjugative transfer functions observed in cells containing pad1 trab mutations, verifying a link between trab function and pheromone "shutdown." tests with a series of pad1 mini-plasmids indicated that the ... | 1991 | 1924555 |
| observation and theory in psychoanalysis: the self psychology of heinz kohut. | the development of self psychology by heinz kohut illustrates the influence of observational method on theory formation in psychoanalysis. in 1959 kohut began to emphasize empathy and introspection over the traditional combination of free association and evenly suspended attention. this became an important part of a process of revision in psychoanalytic theory which culminated in self psychology. this paper demonstrates how and why that particular change in observational method influenced that p ... | 2007 | 1924603 |
| cholestatic jaundice associated with captopril therapy. | captopril has attained widespread use as an effective agent in the treatment of heart failure and hypertension. dermatological, renal and haematological toxicity associated with its use has been widely described and is usually well recognized. there have been comparatively few reports implicating it as causing hepatic drug reactions. most descriptions have emphasized strongly cholestatic features, although a mixed hepatocellular cholestatic picture and predominant hepatocellular reactions have b ... | 2007 | 1932674 |
| [the development of osseointegrated implants]. | 2007 | 1932767 | |
| imaging of the temporomandibular joint in juvenile rheumatoid arthritis. | 2007 | 1932822 | |
| effect of oil-contaminated sediment on the longhorn sculpin (myoxocephalus octodecemspinosus) following chronic exposure. | 2007 | 1932866 | |
| alcohol as a key area. | 2007 | 1932941 | |
| radiographic examination of the lumbar spine in a community hospital: an audit of current practice. | to assess general practitioners' decisions to request lumbar spine radiographs according to the guidelines of the royal college of radiologists. | 2007 | 1932970 |
| drug use during breast-feeding. | the physicochemical and pharmacokinetic factors involved in transfer of drugs into breast milk are reviewed. passage of drugs into milk can best be viewed as a two-compartment system. various ratios of the drug concentration values in the two compartments and ratios of maternal-to-infant intake have been described. knowledge of the limitations of these methods is necessary to properly interpret and apply the literature on drug excretion into breast milk. factors involved in choosing a drug for a ... | 1991 | 1934918 |
| growth of vibrio vulnificus in serum from alcoholics: association with high transferrin iron saturation. | 1991 | 1940460 | |
| doping control of anabolic steroids. | 2006 | 1940836 | |
| mammography quality assurance. | 2007 | 1950889 | |
| lead use in california industry: its prevalence and health implications. | an estimated 230,000 workers were reported to work in lead-using activities as a result of a 1986 statistical survey of employers in california. however, 68% of these workers worked in activities of relatively low hazard. this included 114,000 workers engaged in electronic soldering. over 1800 workers were reported to work in battery manufacture, a relatively high-hazard activity, but with consistent monitoring and protection. in contrast, over 4300 workers were involved in radiator repair activ ... | 2007 | 1951050 |