Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| previous exposure to dengue virus is associated with increased zika virus burden at the maternal-fetal interface in rhesus macaques. | concerns have arisen that pre-existing immunity to dengue virus (denv) could enhance zika virus (zikv) disease, due to the homology between zikv and denv and the observation of antibody-dependent enhancement (ade) among denv serotypes. to date, no study has examined the impact of pre-existing denv immunity on zikv pathogenesis during pregnancy in a translational non-human primate model. here we show that macaques with a prior denv-2 exposure had a higher burden of zikv vrna in maternal-fetal int ... | 2021 | 34329306 |