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identification of dermatophilus congolensis from lower leg dermatitis of cattle in kerala, india.this study was conducted to identify the aetiological agents associated with a particular type of lower leg dermatitis, locally called pododermatitis, among dairy cattle in kerala. skin scabs and scrapings were collected aseptically from 82 naturally occurring cases of lower leg dermatitis in cattle and were subjected to direct microscopical examination and bacterial and fungal culture. microscopical examination of the skin scrapings with 10% potassium hydroxide revealed fungal spores in hair sh ...201527044156
antifungal susceptibility and virulence factors of clinically isolated dermatophytes in tehran, iran.dermatophytes possess a wide array of virulence factors and various antifungal susceptibility patterns which influence their pathogenesis in humans and animals. the aim of this study was to evaluate antifungal susceptibility and keratinase and proteinase activity of 49 dermatophyte strains from the genera microsporum, trichophyton and epidermophyton which were isolated from human cases of dermatophytosis.201627092223
evaluation of incubation time for dermatophytes cultures.in general, it is recommended to incubate dermatophytes cultures for a minimum of 4 weeks. several aspects of routine fungal cultures should be evaluated in order to implement appropriate and necessary changes. the aim of this study was to determine the optimum incubation time for routine dermatophytes cultures, analysing the time to find first fungal growth by visual observation. we recorded the time when the initial growth was detected for all dermatophyte isolates during a 4-year period. a to ...201627144472
superficial mycoses associated with diaper dermatitis.diapers create particular conditions of moisture and friction, and with urine and feces come increased ph and irritating enzymes (lipases and proteases). fungi can take advantage of all these factors. candida yeasts, especially c. albicans, are responsible for the most frequent secondary infections and are isolated in more than 80 % of cases. correct diagnosis is important for ensuring the correct prescription of topical antimycotics. nystatin, imidazoles and ciclopirox are effective. it is impo ...201627193417
[superficial mycoses: casuistry of the mycology department of the instituto nacional de higiene "rafael rangel", caracas, venezuela (2001-2014)].the superficial mycoses are very common infectious diseases and therefore are a frequent reason for medical consultation. the aim of this study was to determine the diagnostic frequency of superficial mycoses in the mycology department of the instituto nacional de higiene "rafael rangel" during 14 years (2001-2014). a retrospective cross-sectional study was performed to review the mycological records of patients with presumptive diagnosis of superficial mycosis. nails, hairs and epidermal scales ...201627382801
sensitization and cross-reactions of dermatophyte and candida albicans allergens in patients with chronic urticaria.chronic fungal infections are known to exacerbate allergic symptoms, including those of asthma and chronic urticaria (cu). we applied four prepared fungal antigens of trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum, and candida albicans to examine sensitization to each in subjects with cu and onychomycosis and in healthy subjects, and to evaluate the etiologic role of dermatophytic infection in cu and observe any cross-reactions among these four antigens.201627420771
preparation and physicochemical characterization of topical chitosan-based film containing griseofulvin-loaded liposomes.griseofulvin is an antifungal drug and is available as oral dosage forms. development of topical treatment could be advantageous for superficial fungal infections of the skin. in this study, films prepared from the incorporation of griseofulvin-loaded liposomes in chitosan film for topical drug delivery in superficial fungal infections. the properties of the films were characterized regarding mechanical properties, swelling, ability to transmit vapor, drug release, thermal behavior, and antifung ...201727429928
molecular identification and phylogenetical analysis of dermatophyte fungi from latin america.dermatophytes constitute a complex group of fungi, comprised of by the genera trichophyton, epidermophyton and microsporum. they have the ability to degrade keratin and cause human and animal infections. molecular techniques have made their identification faster and more accurate, and allowed important advances in phylogenetic studies. we aim to identify molecularly and to determine the phylogenetic relationships in dermatophyte fungi from brazil and other latin american countries, using dna seq ...201627432316
antidermatophytic activity of ethanolic extract from croton tiglium.dermatophytosis, which is caused mainly by genera of trichophyton, epidermophyton, and microsporum, is a frequent dermatological problem in tropical and subtropical countries. investigations were carried out in this study to evaluate the antidermatophytic activity of the stems, leaves, and seeds of croton tiglium, one of the traditional medicine plants indigenous to asia. ethanolic extracts of the stems, leaves, and seeds of c. tiglium were prepared by cold soak or heat reflux methods. the antid ...201627446946
characterization of clinically important dermatophytes in north of iran using pcr-rflp on its region.dermatophytosis is considered as one of the major public health problems in the world. accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. in this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture.201627496524
epidemiological trends of dermatophytosis in tehran, iran: a five-year retrospective study.dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. the aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in tehran, iran.201627520535
econazole nitrate foam 1% improves the itch of tinea pedis.econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by <em>trichophyton rubrum, trichophyton mentagrophytes,</em> and <em>epidermophyton floccosum</em> in patients 12 years of age and older. the symptom of itch or pruritus was evaluated in two randomized, double-blind, parallel-group, vehicle-controlled, multicenter phase iii studies in which econazole foam was compared with foam vehicle in subjects with interdigital tinea pedis. a thin, uniform ...201627602974
antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum.in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ...201627706019
the changing face of dermatophytic infections worldwide.dermatophytes evolve along with the geography and socioeconomic conditions. epidermophyton floccosum, microsporum audouinii and trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of trichophyton rubrum, trichophyton interdigitale, trichophyton tonsurans and microsporum canis incr ...201727783316
toward a novel multilocus phylogenetic taxonomy for the dermatophytes.type and reference strains of members of the onygenalean family arthrodermataceae have been sequenced for rdna its and partial lsu, the ribosomal 60s protein, and fragments of β-tubulin and translation elongation factor 3. the resulting phylogenetic trees showed a large degree of correspondence, and topologies matched those of earlier published phylogenies demonstrating that the phylogenetic representation of dermatophytes and dermatophyte-like fungi has reached an acceptable level of stability. ...201727783317
nimesulide inhibits pathogenic fungi: pge2-dependent mechanisms.certain non-steroidal anti-inflammatory drugs can inhibit fungal growth, fungal prostaglandin e2 production, and enzyme activation. this study aims to investigate the antifungal effect of nimesulide against pathogenic filamentous fungi and yeast. the experiments detailed below were also designed to investigate whether the action is dependent on e2 fungal prostaglandins. our data showed that nimesulide exhibited potent antifungal activity, mainly against trichophyton mentagrophytes (atcc 9533) an ...201727866353
epidemiology of dermatophytoses in crete, greece.dermatophytoses are among the most frequently diagnosed skin infections worldwide. however, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. the aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in crete, greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. we compared our findings wit ...201627904054
inhibition of dermatophytes by photodynamic treatment with curcumin.treatment of dermatophytoses with currently available antimycotic agents is often tedious and sometimes unsatisfactory. a search for better therapeutic methods-ideally with an immediate fungicidal effect-has, among others, lead to photodynamic procedures as a promising alternative, and recently curcumin was found to be a suitable agent for this application. in this study the effect of photodynamic treatment with curcumin on dermatophytes was tested in vitro wells of microtiter plates were filled ...201728053148
dermatophytosis of the scrotum, penis and lip.a young male had tinea cruris due to epidermophyton floccosum. he had associated dermatophytosis of the scrotum, penis and upper lip from which the same species of fungus was isolated. on the lip, the lesion extended to the vermilion area (prolabium) of the lip and the term 'tinea labialis' is suggested for this condition.201728145332
computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes.dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. the infection known as dermatophytosis, caused by members of the genera microsporum, trichophyton, and epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). the identification of evolutionary relationship between thes ...201628149055
clinico mycological study of dermatophytosis in a coastal area.clinico-mycological features of one hundred patients suffering from tinea cruris are reported. ninety two per cent are males and 79% are in the age group of 11-39 years. involvement of axillae is seen in four penile involvement in five patients. 'twenty-eight patients have tinea corporis and nine tinea vesicolor also. seventy seven patients show isolation of dernm-tophytes by culture. the commonest species of dermatophytes is trichophyron rubrum (57.1%) followed by t. mentagraphytes (31.20/o), e ...201728176711
mycology of cutaneous fungal infections in ambajogai: a rural area.two hundred and eithteen cases of fungal skin infections were studied. tinea cruris was most common (34.4%), followed by tinea corporis (23.8%) znd tinea pedis (21.6%). tinea versicolor (8.7%) tinea manum (4.6%) tinea ungaium (3.7%) and tinea capitis (3.2%) were also seen. the male: female ratio was 4:1. the total isolates were 117. trichophyton rubrum was the most common isolate (35%). closely followed by epidermophyton floccosum (31.6%). trichphyton mentagrophytes (17.9%), malassezia furfur (1 ...201728211405
antidermatophytic and protease-inhibiting activities of zerumbone: a natural sesquiterpene from the rhizome of zingiber zerumbet (l.) roscoe ex j.e; smith.due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will help in restricting inflammatory response associated with dermatophytoses.201728216875
chemical characterisation and biological activity of leaf essential oils obtained from pistacia terebinthus growing wild in tunisia and sardinia island.in the present work the chemical compositions, measured by gc and gc-ms, of the essential oils obtained by hydrodistillation from leaves of pistacia terebinthus collected in bizerte (tunisia) and baunei (italy) are reported. both essential oils possessed high content of monoterpene hydrocarbons (86.3% and 90.9%, respectively), being α-pinene (62.4 vs. 35.0)%, camphene (3.0 vs. 2.4)%, β-pinene (12.1 vs. 4.5)%, terpinolene (1.7 vs. 35.2)% and β-phellandrene (3.8 vs. 4.5)% the main components. the ...201728278668
enzymatic and non-enzymatic virulence activities of dermatophytes on solid media.dermatophytes are keratinophilic fungi causing superficial cutaneous infections that account 20-25% of the global population. as per literature search, there is a dearth in the study on virulence factors of dermatophytes from the indian sub-continent and moreover the association of the virulence factors and the host tissue in vitro helps in understanding the host-pathogen interaction.201728384862
diagnosis of dermatophytosis by conventional methods and comparatative analysis of sabouraud dextrose agar and dermatophyte test medium for isolation of dermatophytes.dermatophytosis is a fungal disease which ranked as one of the most common cutaneous condition in all over the world. the aim of this cross sectional observational study is to identify the etiological agent of dermatophytosis and comparison of sabouraud dextrose agar (sda) and dermatophyte test medium (dtm) for the primary isolation of dermatophytes among the clinically suspected cases of dermatophytosis from the outpatient department of dermatology and venereology, mymensingh medical college ho ...201728588164
composition and antifungal activity of zhumeria majdae essential oil.essential oils extracted from different plants are extensively used in perfume, beverage, and food industries and are reported to exhibit antimicrobial activities against a variety of fungi. zhumeria majdae belonging to the lamiaceae family is a rare and endemic medicinal plant species in iran, with a strong and pleasant odor. the leaves of this plant have been used for many years as an antiseptic carminative agent for the treatment of stomachache (especially in infants) and dysmenorrhea.201528680999
a study on etiologic agents and clinical manifestations of dermatophytosis in yazd, iran.dermatophytosis is one of the most common infections of skin, hair, and nails, caused by a group of keratinophilic fungi known as dermatophytes. species identification of these fungi is of great significance from epidemiological and therapeutic points of view. the objective of the present study was to investigate dermatophytosis and its causative agents in patients, referring to the central mycology laboratory of yazd university of medical sciences, yazd, iran.201528681000
dermatophytosis and dermatomycosis in pune.dermatophytosis and dermatomycosis in patients reporting to command hospital (sc) were studied over a period of 3 years. a total of 126 cases were investigated. commonest clinical diagnosis was tinea corporis (39.68%) followed by onychomycosis (20.63%). some patients had infections of multiple sites. direct examination under koh and dimethyl sulfoxide (dmso) revealed fungal elements in 43 (34.12%) cases. fungi were isolated from 44 (34.92%) cases. commonly isolated fungi were candida albicans 11 ...199928775555
anti-dermatophyte activity of leguminosae plants from southern brazil with emphasis on mimosa pigra (leguminosae).intensive prophylactic use of antifungals leads to the increase of drug resistance and the need for new and more effective treatments are real. plants from leguminosae family are rich in flavonoids, for which numerous biological activities have been described, including antifungal effects.201728822705
distribution of species of dermatophyte among patients at a dermatology centre of nghean province, vietnam, 2015-2016.vietnam is a tropical country so fungal diseases including dermatophytosis may be prevalent, but epidemiological profiles of agents responsible for the infection have rarely been reported.201728831770
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