Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| natural human plasmodium infections in major anopheles mosquitoes in western thailand. | the thai-myanmar border is a remaining hotspot for malaria transmission. malaria transmission in this region continues year-round, with a major peak season in july-august, and a minor peak in october-november. malaria elimination requires better knowledge of the mosquito community structure, dynamics and vectorial status to support effective vector control. | 2016 | 26762512 |
| effect of cymbopogon citratus (lemongrass) and syzygium aromaticum (clove) oils on the morphology and mortality of aedes aegypti and anopheles dirus larvae. | cymbopogon citratus (lemongrass) and syzygium aromaticum (clove) oils were evaluated to determine mortality rates, morphological aberrations, and persistence when used against third and fourth larval instars of aedes aegypti and anopheles dirus. the oils were evaluated at 1, 5, and 10 % concentrations in mixtures with soybean oil. persistence of higher concentrations was measured over a period of 10 days. for ae. aegypti, both plant oils caused various morphological aberrations to include deform ... | 2016 | 26796022 |
| population genetics of plasmodium vivax in four rural communities in central vietnam. | the burden of malaria in vietnam has drastically reduced, prompting the national malaria control program to officially engage in elimination efforts. plasmodium vivax is becoming increasingly prevalent, remaining a major problem in the country's central and southern provinces. a better understanding of p. vivax genetic diversity and structure of local parasite populations will provide baseline data for the evaluation and improvement of current efforts for control and elimination. the aim of this ... | 2016 | 26872387 |
| phase 1/2a trial of plasmodium vivax malaria vaccine candidate vmp001/as01b in malaria-naive adults: safety, immunogenicity, and efficacy. | a vaccine to prevent infection and disease caused by plasmodium vivax is needed both to reduce the morbidity caused by this parasite and as a key component in efforts to eradicate malaria worldwide. vivax malaria protein 1 (vmp001), a novel chimeric protein that incorporates the amino- and carboxy- terminal regions of the circumsporozoite protein (csp) and a truncated repeat region that contains repeat sequences from both the vk210 (type 1) and the vk247 (type 2) parasites, was developed as a va ... | 2016 | 26919472 |
| anopheles subpictus carry human malaria parasites in an urban area of western india and may facilitate perennial malaria transmission. | india contributes 1.5-2 million annual confirmed cases of malaria. since both parasites and vectors are evolving rapidly, updated information on parasite prevalence in mosquitoes is important for vector management and disease control. possible new vector-parasite interactions in goa, india were tested. | 2016 | 26919828 |
| comparative studies on the stenogamous and eurygamous behavior of eight anopheles species of the hyrcanus group (diptera: culicidae) in thailand. | establishment of laboratory colony is essential for mosquito-borne-disease research. mating behavior of stenogamous anopheles peditaeniatus and seven eurygamous species (anopheles argyropus, anopheles crawfordi, anopheles nigerrimus, anopheles nitidus, anopheles paraliae (=an. lesteri), anopheles pursati and anopheles sinensis), were investigated and compared in this study. the self-mating success of adult mosquitoes in different size cages at two density resting surface (drs) values, 3.6 and 7. ... | 2016 | 27023618 |
| predicting the geographical distributions of the macaque hosts and mosquito vectors of plasmodium knowlesi malaria in forested and non-forested areas. | plasmodium knowlesi is a zoonotic pathogen, transmitted among macaques and to humans by anopheline mosquitoes. information on p. knowlesi malaria is lacking in most regions so the first step to understand the geographical distribution of disease risk is to define the distributions of the reservoir and vector species. | 2016 | 27125995 |
| where chloroquine still works: the genetic make-up and susceptibility of plasmodium vivax to chloroquine plus primaquine in bhutan. | bhutan has made substantial progress in reducing malaria incidence. the national guidelines recommend chloroquine (cq) and primaquine (pq) for radical cure of uncomplicated plasmodium vivax, but the local efficacy has not been assessed. the impact of cases imported from india on the genetic make-up of the local vivax populations is currently unknown. | 2016 | 27176722 |
| transmission blocking potency and immunogenicity of a plant-produced pvs25-based subunit vaccine against plasmodium vivax. | malaria transmission blocking (tb) vaccines (tbvs) directed against proteins expressed on the sexual stages of plasmodium parasites are a potentially effective means to reduce transmission. antibodies induced by tbvs block parasite development in the mosquito, and thus inhibit transmission to further human hosts. the ookinete surface protein p25 is a primary target for tbv development. recently, transient expression in plants using hybrid viral vectors has demonstrated potential as a strategy fo ... | 2016 | 27177945 |
| lap-like process as an immune mechanism downstream of ifn-γ in control of the human malaria plasmodium vivax liver stage. | ifn-γ is a major regulator of immune functions and has been shown to induce liver-stage plasmodium elimination both in vitro and in vivo. the molecular mechanism responsible for the restriction of liver-stage plasmodium downstream of ifn-γ remains uncertain, however. autophagy, a newly described immune defense mechanism, was recently identified as a downstream pathway activated in response to ifn-γ in the control of intracellular infections. we thus hypothesized that the killing of liver-stage m ... | 2016 | 27185909 |
| shrinking the malaria map in china: measuring the progress of the national malaria elimination programme. | remarkable progress has been made towards the elimination of malaria in china since the national malaria elimination programme (nmep) was launched in 2010. the incidence of locally-acquired malaria cases has declined rapidly and endemic areas have also dramatically shrunk. in total, 3 078 malaria cases were reported in 2014, but only 56 cases were indigenous. in order to further promote the elimination programme, we reviewed the progress of and experiences associated with malaria elimination in ... | 2016 | 27197517 |
| asymptomatic plasmodium infections in 18 villages of southern savannakhet province, lao pdr (laos). | a large fraction of plasmodium infections do not cause clinical signs and symptoms of disease and persist at densities in blood that are not detectable by microscopy or rapid diagnostic tests. these infections may be critical as a transmission reservoir in areas of low malaria endemicity. understanding the epidemiology of these infections would be helpful for malaria elimination. | 2016 | 27234446 |
| detection of putative antimalarial-resistant plasmodium vivax in anopheles vectors at thailand-cambodia and thailand-myanmar borders. | monitoring of multidrug-resistant (mdr)falciparum and vivax malaria has recently been included in the global plan for artemisinin resistance containment (gparc) of the greater mekong sub-region, particularly at the thailand-cambodia and thailand-myanmar borders. in parallel to gparc, monitoring mdr malaria parasites in anopheline vectors is an ideal augment to entomological surveillance. employing plasmodium- and species-specific nested pcr techniques, only p. vivax was detected in 3/109 salivar ... | 2016 | 27244954 |
| semi-field evaluation of metofluthrin-impregnated nets on host-seeking aedes aegypti and anopheles dirus. | the efficacy of a metofluthrin-impregnated net (min) known as the "mushikonazu" on the house entry behavior of female aedes aegypti and anopheles dirus mosquitoes was evaluated using a semi-field 50-m tunnel setup. while the min is labeled for the control of chironomids and moth flies, this study determined the feasibility of using the device, given its current construction and metofluthrin formulation, as a spatial repellent against mosquitoes. sentinel and cone bioassays were used to determine ... | 2016 | 27280351 |
| artemisinin-resistant plasmodium falciparum malaria. | for more than five decades, southeast asia (sea) has been fertile ground for the emergence of drug-resistant plasmodium falciparum malaria. after generating parasites resistant to chloroquine, sulfadoxine, pyrimethamine, quinine, and mefloquine, this region has now spawned parasites resistant to artemisinins, the world's most potent antimalarial drugs. in areas where artemisinin resistance is prevalent, artemisinin combination therapies (acts)-the first-line treatments for malaria-are failing fa ... | 0 | 27337450 |
| comparative mt genomics of the tipuloidea (diptera: nematocera: tipulomorpha) and its implications for the phylogeny of the tipulomorpha. | a traditionally controversial taxon, the tipulomorpha has been frequently discussed with respect to both its familial composition and relationships with other nematocera. the interpretation of internal relationships within the tipuloidea, which include the tipulidae sensu stricto, cylindrotomidae, pediciidae and limoniidae, is also problematic. we sequenced the first complete mitochondrial (mt) genome of symplecta hybrida (meigen, 1804), which belongs to the subfamily chioneinae of family limoni ... | 2016 | 27341029 |
| evolution of the transmission-blocking vaccine candidates pvs28 and pvs25 in plasmodium vivax: geographic differentiation and evidence of positive selection. | transmission-blocking (tb) vaccines are considered an important tool for malaria control and elimination. among all the antigens characterized as tb vaccines against plasmodium vivax, the ookinete surface proteins pvs28 and pvs25 are leading candidates. these proteins likely originated by a gene duplication event that took place before the radiation of the known plasmodium species to primates. we report an evolutionary genetic analysis of a worldwide sample of pvs28 and pvs25 alleles. our result ... | 2016 | 27347876 |
| 'nature or nurture': survival rate, oviposition interval, and possible gonotrophic discordance among south east asian anophelines. | mosquito survival, oviposition interval and gonotrophic concordance are important determinants of vectorial capacity. these may vary between species or within a single species depending on the environment. they may be estimated by examination of the ovaries of host-seeking mosquitoes. | 2016 | 27405767 |
| tyrosine hydroxylase is crucial for maintaining pupal tanning and immunity in anopheles sinensis. | tyrosine hydroxylase (th), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into dopa. although expression and regulation of th have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzyme during mosquito development. in the current study, silencing of asth during the time period of continuous high expression in anopheles sinensis pupae led to significant impairmen ... | 2016 | 27416870 |
| the relationship of malaria between chinese side and myanmar's five special regions along china-myanmar border: a linear regression analysis. | understanding malaria along the international border of two countries is important for malaria control and elimination; however, it is difficult to investigate a quantitative relationship between two countries' border areas due to a shortage of malaria surveillance data. | 2016 | 27430217 |
| key knowledge gaps for plasmodium vivax control and elimination. | there is inadequate understanding of the biology, pathology, transmission, and control of plasmodium vivax, the geographically most widespread cause of human malaria. during the last decades, study of this species was neglected, in part due to the erroneous belief that it is intrinsically benign. in addition, many technical challenges in culturing the parasite also hampered understanding its fundamental biology and molecular and cellular responses to chemotherapeutics. research on vivax malaria ... | 2016 | 27430544 |
| high plasmodium malariae prevalence in an endemic area of the colombian amazon region. | malaria is a worldwide public health problem; parasites from the genus plasmodium are the aetiological agent for this disease. the parasites are mostly diagnosed by conventional microscopy-based techniques; however, their limitations have led to under-registering the reported prevalence of plasmodium species. this study has thus been aimed at evaluating the infection and coinfection prevalence of 3 species of plasmodium spp., in an area of the colombian amazon region. blood samples were taken fr ... | 2016 | 27467587 |
| vector competence of anopheles kleini and anopheles sinensis (diptera: culicidae) from the republic of korea to vivax malaria-infected blood from patients from thailand. | in total, 1,300 each of anopheles kleini rueda and anopheles sinensis wiedemann sensu stricto (s.s.) females (colonized from the republic of korea) and anopheles dirus peyton & harrison (thai strain) were allowed to feed on blood from thai malaria patients naturally infected with plasmodium vivax the overall oocyst infection rates for an. dirus, an. kleini, and an. sinensis s.s. were 77.4, 46.1, and 45.9%, respectively. the mean number of oocysts was significantly higher for an. dirus (82.7) com ... | 2016 | 27493248 |
| molecular characterization of a lysozyme gene and its altered expression profile in crowded beet webworm (loxostege sticticalis). | there is growing evidence that insects living in high-density populations exhibit an increase in immune function to counter a higher risk of disease. this phenomenon, known as density-dependent prophylaxis, has been experimentally tested in a number of insect species. although density-dependent prophylaxis is especially prevalent in insects exhibiting density-dependent phase polyphenism, the molecular mechanism remains unclear. our previous study demonstrated that the antibacterial activity of l ... | 2016 | 27575006 |
| cow-baited tents are highly effective in sampling diverse anopheles malaria vectors in cambodia. | the accurate monitoring and evaluation of malaria vectors requires efficient sampling. the objective of this study was to compare methods for sampling outdoor-biting anopheles mosquitoes in cambodia. | 2016 | 27577697 |
| malaria elimination challenges in mesoamerica: evidence of submicroscopic malaria reservoirs in guatemala. | even though malaria incidence has decreased substantially in guatemala since 2000, guatemala remains one of the countries with the highest malaria transmission in mesoamerica. guatemala is committed to eliminating malaria as part of the initiative 'elimination of malaria in mesoamerica and the island of hispaniola' (emmie); however, it is still in the control phase. during the past decade, the government strengthened malaria control activities including mass distribution of long-lasting insectic ... | 2016 | 27577992 |
| anopheline species and their plasmodium infection status in aligarh, india. | malaria is a global issue and india contributes substantially to global malaria incidence. information related to malaria vectors is very limited in aligarh. the environmental and climatological situations permit the continual breeding of vectors in permanent breeding sites. this study was designed with the aim to screen all the anophelines species and possible malaria vectors in three different localities of aligarh. anopheles mosquitoes were collected from three different localities (fort, jal ... | 2015 | 27579016 |
| plasmodium cynomolgi infections in rhesus macaques display clinical and parasitological features pertinent to modelling vivax malaria pathology and relapse infections. | plasmodium vivax infections in humans or in new world monkeys pose research challenges that necessitate the use of alternative model systems. plasmodium cynomolgi is a closely related species that shares genetic and biological characteristics with p. vivax, including relapses. here, the haematological dynamics and clinical presentation of sporozoite-initiated p. cynomolgi infections in macaca mulatta (rhesus macaques) are evaluated over a 100-day period. | 2016 | 27590312 |
| role of nf-kβ factor rel2 during plasmodium falciparum and bacterial infection in anopheles dirus. | anopheles mosquitoes transmit malaria which is one of the world's most threatening diseases. anopheles dirus (sensu stricto) is among the main vectors of malaria in south east asia. the mosquito innate immune response is the first line of defence against malaria parasites during its development. the immune deficiency (imd) pathway, a conserved immune signaling pathway, influences anti-plasmodium falciparum activity in anopheles gambiae, an. stephensi and an. albimanus. the aim of the study was t ... | 2016 | 27688040 |
| plasmodium vivax malaria in cambodia. | the cambodian national strategic plan for elimination of malaria aims to move step by step toward elimination of malaria across cambodia with an initial focus on plasmodium falciparum malaria before achieving elimination of all forms of malaria, including plasmodium vivax in 2025. the emergence of artemisinin-resistant p. falciparum in western cambodia over the last decade has drawn global attention to support the ultimate goal of p. falciparum elimination, whereas the control of p. vivax lags m ... | 2016 | 27708187 |
| epidemiology of plasmodium vivax malaria in india. | historically, malaria in india was predominantly caused by plasmodium vivax, accounting for 53% of the estimated cases. after the spread of drug-resistant plasmodium falciparum in the 1990s, the prevalence of the two species remained equivalent at the national level for a decade. by 2014, the proportion of p. vivax has decreased to 34% nationally, but with high regional variation. in 2014, p. vivax accounted for around 380,000 malaria cases in india; almost a sixth of all p. vivax cases reported ... | 2016 | 27708188 |
| the phylogenetic relationships of known mosquito (diptera: culicidae) mitogenomes. | the known mosquito mitogenomes, containing a total of 34 species, which belong to five genera, were collected from genbank, and the practicality and effectiveness of the variation in the complete mitochondrial dna genome and portions of mitochondrial coi gene were assessed to reconstruct the phylogeny of mosquitoes. phylogenetic trees were reconstructed on the basis of parsimony, maximum likelihood, and bayesian (bi) methods. it is concluded that: (1) both mitogenomes and coi gene support the mo ... | 2016 | 27731651 |
| investigating the contribution of peri-domestic transmission to risk of zoonotic malaria infection in humans. | in recent years, the primate malaria plasmodium knowlesi has emerged in human populations throughout south east asia, with the largest hotspot being in sabah, malaysian borneo. control efforts are hindered by limited knowledge of where and when people get exposed to mosquito vectors. it is assumed that exposure occurs primarily when people are working in forest areas, but the role of other potential exposure routes (including domestic or peri-domestic transmission) has not been thoroughly invest ... | 2016 | 27741235 |
| household clustering of asymptomatic malaria infections in xepon district, savannakhet province, lao pdr. | in the lao pdr, malaria morbidity and mortality have remarkably decreased over the past decade. however, asymptomatic infections in rural villages contribute to the on-going local transmission. the primary objective of this study was to explore the characteristics of infections in a malaria-endemic district of the lao pdr. the specific objectives were to investigate the prevalence and species of malaria parasites using molecular methods and to assess individual and household parasite levels and ... | 2016 | 27756391 |
| serological markers to measure recent changes in malaria at population level in cambodia. | serological markers for exposure to different plasmodium species have recently been used in multiplex immunoassays based on the luminex technology. however, interpretation of the assay results requires consideration of the half-life of specific antibodies against these markers. therefore, the aim of the present study was to document the half-life of malaria specific serological makers, as well as assessing the sensitivity of these markers to pick up recent changes in malaria exposure. | 2016 | 27809852 |
| biology, distribution and control of anopheles (cellia) minimus in the context of malaria transmission in northeastern india. | among six dominant mosquito vector species involved in malaria transmission in india, anopheles minimus is a major species in northeast india and held responsible for focal disease outbreaks characterized by high-rise of plasmodium falciparum infections and attributable death cases. it has been now genetically characterized that among the three-member species of the minimus complex spread in asia, an. minimus (former species a) is prevalent in india including northeastern states and east-central ... | 2016 | 27846911 |
| in vitro effect of seven essential oils on the reproduction of the cattle tick rhipicephalus microplus. | the acaricidal effect of seven essential oils was examined in vitro against the cattle tick (rhipicephalus microplus). engorged female ticks were manually collected in farms of southern brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (juniperus communis), palmarosa (cymbopogon martinii), cedar (cedrus atlantica), lemon grass (cymbopogon citratus), ginger (zingiber officinale), geranium (pelargonium graveolens) and bergamot (citrus aurantium var bergamia) ... | 2016 | 27857849 |
| behavioral responses of anopheles species (culicidae: diptera) with varying surface exposure to pyrethroid-treated netting in an excito-repellency test system. | indoor residual spray (irs) with insecticides has been a procedure used for decades to protect humans from biting mosquitoes and potential vectors of pathogens. the objective of this study was to determine the responses of three wild-caught species of malaria vectors exposed to pyrethroids of three different surface coverage percents using an excito-repellency test box. each species was exposed to three insecticide-treated surfaces at varying exposure levels (full coverage, 50%, and 25% of the m ... | 2016 | 27860013 |
| spatial and space-time distribution of plasmodium vivax and plasmodium falciparum malaria in china, 2005-2014. | despite the declining burden of malaria in china, the disease remains a significant public health problem with periodic outbreaks and spatial variation across the country. a better understanding of the spatial and temporal characteristics of malaria is essential for consolidating the disease control and elimination programme. this study aims to understand the spatial and spatiotemporal distribution of plasmodium vivax and plasmodium falciparum malaria in china during 2005-2009. | 2016 | 27993171 |
| artificial diets for mosquitoes. | mosquito-borne diseases are responsible for more than a million human deaths every year. modern mosquito control strategies such as sterile insect technique (sit), release of insects carrying a dominant lethal (ridl), population replacement strategies (pr), and wolbachia-based strategies require the rearing of large numbers of mosquitoes in culture for continuous release over an extended period of time. anautogenous mosquitoes require essential nutrients for egg production, which they obtain thr ... | 2016 | 28009851 |
| impact of bacillus sphaericus exposure on anopheles dirus's fecundity and resistance development. | mosquitoes are important vectors of many infectious diseases. bacillus sphaericus (bs) is an ideal larvicide and has attracted more and more attention, recently. however, the fundamental research of its application is very limited, especially on the subsequent impact of bs exposure on mosquito's fecundity and resistance emergence. through bioassay, lc50 and lc95 of bs in killing anopheles dirus larvae were determined as 9.793 ± 1.878 iu/l and 62.4 ± 6.438 iu/l at 48 h posttreatment, 7.128 ± 0.91 ... | 2017 | 28012029 |
| infectivity of symptomatic and asymptomatic plasmodium vivax infections to a southeast asian vector, anopheles dirus. | plasmodium vivax is now the predominant species causing malarial infection and disease in most non-african areas, but little is known about its transmission efficiency from human to mosquitoes. because the majority of plasmodium infections in endemic areas are low density and asymptomatic, it is important to evaluate how well these infections transmit. using membrane feeding apparatus, anopheles dirus were fed with blood samples from 94 individuals who had natural p. vivax infections with parasi ... | 2017 | 28043858 |
| mapping of malaria vectors at district level in india: changing scenario and identified gaps. | malaria is one of the six major vector-borne diseases in india, the endemicity of which changes with changes in ecological, climatic, and sociodevelopmental conditions. the anopheline vectors are greatly affected by ecological conditions such as deforestation, urbanization, climate and lifestyle. despite the advent of tools such as geographic information system (gis), the updated information on the distribution of anopheline vectors of malaria is not available. in india, the plan for vector cont ... | 2017 | 28051366 |
| diversity of the bacterial microbiota of anopheles mosquitoes from binh phuoc province, vietnam. | the naturally acquired microbiota of anopheles can influence vector's susceptibility to plasmodium and its capacity to transmit them. microbiota modification is a new challenge to limit disease transmission but it still needs advanced knowledges on bacterial community in anopheles, especially in wild and infected specimens from diverse origin and species. bacterial culture and 16s rrna gene-pcr associated to temporal temperature gradient electrophoresis (ttge) were applied to explore the bacteri ... | 2016 | 28066401 |
| efficient method for establishing f1 progeny from wild populations of anopheles mosquitoes. | the changing malaria situation in madagascar requires additional knowledge on the physiology and behaviour of local mosquito vectors. however, the absence of established colonies for several anopheline species present in madagascar constitutes a limiting factor. to avoid labour intensive work and uncertainty for success of establishing anopheles colonies from malagasy species, field collections of blood-fed females and in-tube forced oviposition were combined to reliably produce large numbers of ... | 2017 | 28069024 |
| spatiotemporal epidemic characteristics and risk factor analysis of malaria in yunnan province, china. | malaria remains an important public health concern in china and is particularly serious in yunnan, a china's provincial region of high malaria burden with an incidence of 1.79/10(5) in 2012. this study aims to examine the epidemiologic profile and spatiotemporal aspects of epidemics of malaria, and to examine risk factors which may influence malaria epidemics in yunnan province. | 2017 | 28077125 |
| surveillance and response for high-risk populations: what can malaria elimination programmes learn from the experience of hiv? | to eliminate malaria, malaria programmes need to develop new strategies for surveillance and response appropriate for the changing epidemiology that accompanies transmission decline, in which transmission is increasingly driven by population subgroups whose behaviours place them at increased exposure. conventional tools of malaria surveillance and response are likely not sufficient in many elimination settings for accessing high-risk population subgroups, such as mobile and migrant populations ( ... | 2017 | 28100237 |
| the fibrinogen-like domain of frep1 protein is a broad-spectrum malaria transmission-blocking vaccine antigen. | frep1 in mosquito midguts facilitates plasmodium falciparum parasite transmission. the fibrinogen-like (fbg) domain of frep1 is highly conserved (>90% identical) among anopheles species from different continents, suggesting that anti-fbg antibodies may block malaria transmission to all anopheline mosquitoes. using standard membrane-feeding assays, anti-frep1 polyclonal antibodies significantly blocked transmission of plasmodium berghei and plasmodium vivax to anopheles gambiae and anopheles diru ... | 2017 | 28533429 |
| single dose primaquine to reduce gametocyte carriage and plasmodium falciparum transmission in cambodia: an open-label randomized trial. | single low dose primaquine (sld pq, 0.25mg/kg) is recommended in combination with artemisinin-based combination therapy (act) as a gametocytocide to prevent plasmodium falciparum transmission in areas threatened by artemisinin resistance. to date, no randomized controlled trials have measured primaquine's effect on infectiousness to anopheline mosquitoes in southeast asia. | 2017 | 28591198 |
| detection of the plasmodium falciparum kelch-13 gene p553l mutation in sporozoites isolated from mosquito salivary glands in south-central vietnam. | plasmodium falciparum has developed resistance against artemisinin in southeast asia. mutations in the p. falciparum kelch-13 (pfk13) gene are associated with artemisinin resistance in vitro and in vivo. we investigated the prevalence of mutations in pfk13 from sporozoite-stage parasites isolated from the salivary glands of anopheles dirus mosquitoes. | 2017 | 28646896 |
| ivermectin susceptibility and sporontocidal effect in greater mekong subregion anopheles. | novel vector control methods that can directly target outdoor malaria transmission are urgently needed in the greater mekong subregion (gms) to accelerate malaria elimination and artemisinin resistance containment efforts. ivermectin mass drug administration (mda) to humans has been shown to effectively kill wild anopheles and suppress malaria transmission in west africa. preliminary laboratory investigations were performed to determine ivermectin susceptibility and sporontocidal effect in gms a ... | 2017 | 28687086 |
| anopheles vectors in mainland china while approaching malaria elimination. | china is approaching malaria elimination; however, well-documented information on malaria vectors is still missing, which could hinder the development of appropriate surveillance strategies and who certification. this review summarizes the nationwide distribution of malaria vectors, their bionomic characteristics, control measures, and related studies. after several years of effort, the area of distribution of the principal malaria vectors was reduced, in particular for anopheles lesteri (synony ... | 2017 | 28734898 |
| status of insecticide resistance in anopheles mosquitoes in ubon ratchathani province, northeastern thailand. | malaria is common in hilly, forested areas along national borders in southeast asia. insecticide resistance in malaria vectors has been detected in a few countries in the greater mekong sub-region (gms), representing a threat to malaria control and prevention. this study aims to determine the insecticide resistance status of anopheles mosquitoes in ubon ratchathani province, northeastern thailand, where increasing number of malaria cases were reported recently. | 2017 | 28743278 |
| quantitative real-time pcr analysis of anopheles dirus tep1 and nos during plasmodium berghei infection, using three reference genes. | quantitative reverse transcription pcr (qrt-pcr) has been an integral part of characterizing the immunity of anopheles mosquitoes towards plasmodium invasion. two anti-plasmodium factors of anopheles, thioester-containing protein 1 (tep1) and nitric oxide synthase (nos), play a role in the refractoriness of anopheles towards plasmodium infection and are generally expressed during infection. however, these are less studied in anopheles dirus, a dominant malaria vector in southeast asia. furthermo ... | 2017 | 28761783 |
| disappearance of anopheles minimus and anopheles dirus from certain malaria endemic areas of assam, india. | orang primary health centre (ophc) and balipara primary health centre (bphc) of assam (india) report mosquito borne diseases annually. current study was performed to ascertain the prevalence of known malaria and japanese encephalitis (je) vectors and their possible role in disease transmission. | 2017 | 29026850 |
| molecular epidemiology of mosquitoes for the transmission of forest malaria in south-central vietnam. | human infection caused by non-human primate malarial parasites, such as plasmodium knowlesi and plasmodium cynomolgi, occurs naturally in southeast asian countries, including vietnam. members of the anopheles dirus species complex are known to be important vectors of human malarial parasites in the forested areas of southern and central vietnam, including those in khanh phu commune and khanh hoa province. recent molecular epidemiological studies in vietnam have reported cases of co-infection wit ... | 2017 | 29046610 |
| natural plasmodium vivax infections in anopheles mosquitoes in a malaria endemic area of northeastern thailand. | there was recently an outbreak of malaria in ubon ratchathani province, northeastern thailand. in the absence of information on malaria vector transmission dynamics, this study aimed to identify the anopheline vectors and their role in malaria transmission. adult female anopheles mosquitoes were collected monthly by human-landing catch in na chaluai district of ubon ratchathani province during january 2014-december 2015. field-captured mosquitoes were identified to species using morphology-based ... | 2017 | 29082435 |
| molecular identification of four members of the anopheles dirus complex using the mitochondrial cytochrome c oxidase subunit i gene. | precise mosquito species identification is an essential step for proper management and control of malaria vectors. misidentification of members in the anopheles dirus complex, some which are primary malaria vectors in thailand and mainland southeast asia, remains problematic because of indistinguishable or overlapping morphological characters between sibling species. moreover, there is a need for alternative methods, since the existing molecular techniques in the literature are not entirely sati ... | 2017 | 29369036 |