Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| an analysis of in vitro b cell immune responsiveness in human lymphatic filariasis. | the immunoregulatory mechanisms involved in b cell function in patients with varying clinical manifestations of bancroftian filariasis were examined by studying the ability of peripheral blood mononuclear cells (pbmc) or pbmc subpopulations from patients with elephantiasis, asymptomatic microfilaremia (mf), and acute tropical pulmonary eosinophilia (tpe) to produce polyclonal and parasite-specific antibody in vitro, both spontaneously and in response to a mitogen (pwm) and to parasite antigen. w ... | 1987 | 3295043 |
| a study of the antigen, antibody and immunecomplex levels in wuchereria bancrofti filariasis with reference to clinical status. | circulating antigens, antibodies to somatic and sheath components of microfilariae (mf) and immune complexes were determined in parallel in different categories of wuchereia bancrofti infection using, respectively, reverse indirect haemagglutination (riha), indirect haemagglutination (iha), indirect immunofluorescent (ifa) and polyethylene glycol (peg) precipitation assays. rabbit hyperimmune anti-w. bancrofti mf serum and mf homogenates were used as reagents. appreciable levels of antigens and ... | 1987 | 3295279 |
| the wellcome trust lecture. inflammatory responses to filarial connective tissue parasites. | the inflammatory responses to lymphatic filariae and to onchocerca volvulus are reviewed with particular attention to evolutionary biology; inflammatory host spectrum; non-specific components; immunoregulation; immune evasion versus immunomodulation; chronic tissue damage and scarring and disease models. basic principles of pathogenesis are emphasized, comparisons drawn with schistosome infection, and critical items of missing information are highlighted. | 1987 | 3295688 |
| the spectrum of disease in lymphatic filariasis. | lymphatic filariasis affects predominantly the poorer sector of a community, who can least afford to have the disease. according to an estimate by the world health organization in 1984, more than 90 million people are currently infected. it is postulated that the different disease manifestations of filariasis are caused by different host immune responses. an understanding of the clinical spectrum of lymphatic filariasis is essential for the effective treatment and control of the disease, and for ... | 1987 | 3297555 |
| antibody responses to human lymphatic filarial parasites. | the lymphatic filarial parasites, brugia and wuchereria, continue to present an immunological puzzle, particularly with respect to the development of natural resistance or damaging disease. we have approached this question by examining humoral responses to a few defined antigens of selected interest from these parasites, using sera from each category in the spectrum of filarial disease. many antigens, such as the major adult surface protein of mr 29,000 (29k), appear to be recognized at all stag ... | 1987 | 3297556 |
| cellular unresponsiveness in patients with soluble circulating antigens in bancroftian filariasis. | 1987 | 3298028 | |
| acute tropical pulmonary eosinophilia. characterization of the lower respiratory tract inflammation and its response to therapy. | although acute tropical pulmonary eosinophilia (tpe) is well recognized as a manifestation of filarial infection, the processes that mediate the abnormalities of the lung in tpe are unknown. to evaluate the hypothesis that the derangements of the lower respiratory tract in this disorder are mediated by inflammatory cells in the local milieu, we utilized bronchoalveolar lavage to evaluate affected individuals before and after therapy. inflammatory cells recovered from the lower respiratory tract ... | 1987 | 3298321 |
| a monoclonal antibody-based enzyme immunoassay for detecting parasite antigenemia in bancroftian filariasis. | we evaluated a monoclonal antibody-based enzyme immunoassay for detecting soluble parasite antigen in sera collected in an area in south india endemic for wuchereria bancrofti. filarial antigen was detected in sera from 56 of 57 microfilaremic patients, 9 of 64 aminofilaremic patients with clinical filariasis, and 11 of 70 endemic controls. antigen was not detected in sera from patients from nonendemic areas who had a variety of other filarial and nonfilarial helminth infections. parasite antige ... | 1987 | 3298458 |
| chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the philippines. | in the course of genetic population surveys of a tribal group of the philippine negritos living on mindanao island, microfilariae (wuchereria bancrofti) were incidentally found on the microscopic slides for a cytogenetic investigation. structural chromosome aberrations in the cultured leukocytes from 19 filaria-infected and 22 uninfected subjects were studied. the frequencies of chromosome type aberrations such as dicentrics and chromosome breaks in the infected subjects were significantly highe ... | 1986 | 3298746 |
| efficiency of papain-treated microfilariae of wuchereria bancrofti (var. pacifica) as antigen for serodiagnosis of bancroftian filariasis in french polynesia. | papain-treated microfilariae of wuchereria bancrofti have been used as antigen for indirect fluorescent assay: 0% of non-endemic sera, 8% of healthy exposed polynesians, 48% of clinical patients and 96% of microfilaraemic subjects were positive by this test. the geometric mean titres were 22, 41, 147 and 605 respectively. untreated microfilariae were unsuitable for diagnostic purposes. dirofilaria immitis adult sections showed low reactivity, giving poor discrimination between non-endemic and mi ... | 1986 | 3299894 |
| the disappearance of bancroftian filariasis from charleston, south carolina. | i suggest the hypothesis that bancroftian filariasis, endemic since the early days of slavery in charleston, south carolina, disappeared around 1930 by virtue of the long-term effects of a municipal sewerage-water system begun in the 1890s or thereabouts. these public works, originally intended to abate typhoid and related diseases, helped to eliminate filariasis by reducing the availability of polluted domestic waters which are the preferred breeding sites for the urban vector, culex quinquefas ... | 1987 | 3300389 |
| [studies on the role of residual microfilaremia in bancroftian filariasis transmission in controlled areas]. | 1987 | 3304654 | |
| [determination of circulating antigens in human filariasis by means of a modified sandwich enzyme-linked immunosorbent assay (ms-elisa) using monoclonal antibodies]. | 1987 | 3304699 | |
| a survey of bancroftian filariasis in the dominican republic. | 1987 | 3305853 | |
| filariasis of the breast. | filariasis of the breast is usually seen in endemic areas. involvement may, however, present years after leaving an endemic area and be associated with circulating microfilariae. we describe the findings in a woman who developed a breast mass three years after a visit to her native india. | 1987 | 3307689 |
| [longitudinal surveillance in areas with bancroftian filariasis virtually eradicated in guizhou]. | 1987 | 3308161 | |
| [estimation of some entomological parameters in relation to the transmission of bancroftian filariasis]. | 1987 | 3308162 | |
| [epidemiological features of residual infection foci of filariasis in controlled areas and purifying measures]. | 1987 | 3308362 | |
| filarial chyluria: an immunological and renal function study. | 1987 | 3308835 | |
| relevance of species specific filarial antigens for diagnosis. | 1986 | 3309026 | |
| detection and diagnostic utility of in vitro and in vivo released antigens in bancroftian filariasis. | 1986 | 3309030 | |
| relative impact of integrated vector control strategy vis-a-vis conventional control strategy on bancroftian filariasis in pondicherry. | 1986 | 3309031 | |
| control of filariasis in india. | 1986 | 3309032 | |
| control of bancroftian filariasis in rural areas through selected treatment with diethylcarbamazine. | 1986 | 3309033 | |
| a filariasis survey among the migratory labourers at alwar, rajasthan. | 1986 | 3309034 | |
| in vitro maintenance and development of wuchereria bancrofti microfilariae. | 1986 | 3309035 | |
| lymphatic filariasis: lymphocyte sub-populations in wuchereria bancrofti infection. | 1986 | 3309036 | |
| epidemiological study on lymphatic filariasis in an endemic zone of orissa. | 1986 | 3309037 | |
| filaria specific monoclonal antibodies for diagnosis. | 1986 | 3309039 | |
| effectiveness of membrane feeding method in relation to development of filarial infective larvae in culex quinquefasciatus. | 1986 | 3309040 | |
| factor influencing acceptance and non-acceptance to dec in a bancroftian endemic area. | 1986 | 3309041 | |
| igg antibody subclasses in human filariasis. differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection. | the four subclasses of igg are distinct in structure, function, and degree of participation in the antibody response to complex antigens. looking for differential responsiveness of potential pathogenetic significance, we have analyzed both quantitatively and qualitatively the filaria-specific igg subclass responses of 20 patients with lymphatic filariasis presenting either with chronic lymphatic obstructive pathology and elephantiasis (cp) or with asymptomatic microfilaremia (mf). subclass-speci ... | 1987 | 3309059 |
| in vitro cultivation of third stage larvae of wuchereria bancrofti to the fourth stage. | third stage larvae of wuchereria bancrofti obtained from laboratory-infected mosquitoes grew and molted to the fourth stage in vitro. the culture medium which supported the best growth and development consisted of a 1:1 mixture (v/v) of two commercially available cell culture media, nctc 135 and iscove's modified dulbecco's medium supplemented with 10% human serum or plasma and an antibacterial/antimycotic mixture. cultures were incubated at 37 degrees c in an atmosphere of either 5% or 8% co2 i ... | 1987 | 3310688 |
| evaluation of specific humoral immune responses in human filariasis. | using the antigens prepared from adult worms of b. malayi and d. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. it was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. of the two antigens used, b. malayi adult antigen was found to be superior to d. immi ... | 1987 | 3311932 |
| prevalence survey of filariasis in two villages in chingleput district of tamil nadu. | 1987 | 3311986 | |
| immunosuppression in clinical filariasis. | 1987 | 3311987 | |
| the silvered leaf monkey (presbytis cristata) as a model for human bancroftian filariasis. | 1987 | 3312807 | |
| [filariasis caused by wuchereria bancrofti cobbold, 1877 (nematoda: filaroidea). report of a case in cuba]. | 1987 | 3313564 | |
| development of brugia malayi in mongolian gerbils previously exposed to wuchereria bancrofti. | twelve mongolian gerbils, meriones unguiculatus, were infected with 100 third-stage larvae of wuchereria bancrofti. one month later these animals, along with 4 control animals, were given 100 third-stage larvae of brugia malayi. eleven of the 12 experimental animals and the 4 controls survived, and 8 of the experimental animals and all of the controls demonstrated microfilaremia after 3 months. the animals were killed at 6-months post-infection and examined for parasites. one w. bancrofti larva ... | 1987 | 3313736 |
| filariasis in tak province, northwest thailand: the presence of subperiodic variant wuchereria bancrofti. | the microfilariae found in carriers at tak province, northwestern thailand were morphologically and morphometrically studied. it was found that the parasites conformed to that of w. bancrofti microfilaria. the microfilarial periodicity as determined from four carriers was found to be nocturnally (early evening) subperiodic type showing a distinct peak at 1800 hours. | 1987 | 3313738 |
| aedes (finlaya) togoi theobald 1907, chanthaburi strain, a laboratory vector in studies of filariasis in thailand. | 1987 | 3313743 | |
| scanning electron microscopic study of third-stage larva of wuchereria bancrofti and brugia malayi in thailand. | 1987 | 3313744 | |
| [finding of a case of filariasis probably native in the state of ceará]. | 1986 | 3317558 | |
| retroperitoneal cyst of filarial origin. | 1987 | 3320023 | |
| study of the relation between tissue typing and occurrence of filariasis and its complications in egypt. | 1987 | 3320221 | |
| [filarial multiparasitism in the savannah zone in burkina faso]. | from june 1985 to may 1986, 1.209 consulting patients were examined for filariae in skin and blood. among patients with microfilariae 17% had associations of filarial infections. the multiple infections rate seemed more important in man than woman and increased with age. the results showed that associations were not due to chance only. the frequencies of associations between dipetalonema perstans and onchocerca volvulus at one hand, dipetalonema perstans and wuchereria bancrofti on the other han ... | 1987 | 3323769 |
| wheat germ agglutinin specifically binds to the surface of infective larvae of wuchereria bancrofti. | 1987 | 3325623 | |
| clinical manifestations of wuchereria bancrofti filariasis in an endemic village in the nile delta. | 1987 | 3327478 | |
| the pathology of lymphoreticular and genital tissues of silvered leaf monkeys (presbytis cristata) experimentally infected with wuchereria bancrofti. | the discovery of the silvered leaf monkey, presbytis cristata, as a suitable experimental host for the human filarial parasite, wuchereria bancrofti, opened the door for major advances in our understanding of the disease caused by this parasite. to study the pathogenesis of bancroftian filariasis in this model, 15 adult p. cristata which had been experimentally infected with 250 infective third-stage larvae of the parasite were examined. after inoculation with larvae, the monkeys were maintained ... | 1987 | 3327870 |
| natural infections of wuchereria bancrofti in aedes (stegomyia) polynesiensis and aedes (finlaya) samoanus in samoa. | seven years after the 2nd mass treatment of the population with diethylcarbamazine, transmission of subperiodic wuchereria bancrofti was studied in four villages in samoa during one year by means of biting catches of aedes polynesiensis and a. samoanus. 2 villages were coastal, one inland bush and the other an inland coconut plantation community. overall infection and infective rates from 6702 ae. polynesiensis were 0.84 and 0.27% respectively, and the infection rate from 2858 ae. samoanus, coll ... | 1987 | 3328327 |
| distribution of vectors, transmission indices and microfilaria rates of subperiodic wuchereria bancrofti in relation to village ecotypes in samoa. | aedes polynesiensis and ae. samoanus biting densities and wuchereria bancrofti infection and infective rates were studied in 47 villages throughout the islands of samoa upolu, manono and savaii during 1978-79, and microfilaria (mf) rates were surveyed in 28 of the villages. the mf rate was correlated with both infection and infective rates of ae. polynesiensis in upolu, but not of ae. samoanus. in upolu, ae. polynesiensis was apparently the major vector. it was relatively more abundant in more c ... | 1987 | 3328328 |
| bancroftian filariasis in coastal north trinidad: the effects of mass chemotherapy using spaced doses of diethylcarbamazine citrate on human microfilaraemias and vector infection rates. | the effects of a mass chemotherapy programme using spaced doses of diethylcarbamazine citrate on wuchereria bancrofti microfilaraemias and vector infection rates were studied in an isolated rural community of 650 people in north trinidad where a microfilaria rate of 15% had previously been recorded. a single oral dose of 6 mg/kg body weight was given at monthly intervals for one year. after 6 months, 79% (52/66) of persons previously microfilaraemic had become negative. after 12 months the negat ... | 1987 | 3328349 |
| a mark-recapture experiment with the filariasis vector anopheles punctulatus in papua new guinea. | a capture-recapture experiment with the filariasis vector anopheles punctulatus from papua new guinea (png) is described. eight hundred and ninety-seven engorged females collected indoor resting or in landing catches were released, and 82 were subsequently recaptured. infection rates were higher in recaptured mosquitoes than in unmarked ones. recapture rates declined exponentially with distance from the release site, but an infected female was recaptured 1.8 km from the release site. the estimat ... | 1987 | 3328568 |
| fractionation and characterization of urinary filarial antigen in bancroftian filariasis. | urine samples from microfilaraemic patients were concentrated and fractionated by gel chromatography on ultrogel aca 44. four protein fractions labelled as ufa c1, ufa c2, ufa c3 and ufa c4 were tested for filarial antigenicity by sandwich elisa. ufa c1 and ufa c2 showed antigenic activity. on further analysis by sds-page, ufa c1 and ufa c2 showed antigenic components with mw ranging from 10.4 k to 123 k. ufa c1-1 and ufa c2-2 showed high antigen titre in elisa. urinary albumin was observed as a ... | 1987 | 3329520 |
| [effectiveness of mass chemotherapy campaigns with diethylcarbamazine on blood microfilaria of wuchereria bancrofti in mayotte]. | an evaluation of the microfilarial index has been carried out in a randomised population, during april and may 1986, to determine the efficacy of long course mass chemotherapy. a single dose of dec at 6 mg/kg was distributed to the whole population of the island, every 4 months, in 1985 and 1986. the survey was done three months after the treatment. 1,307 thick blood films have been collected in night-time. the prevalence of microfilaremia was 1.9% as compared with 17.1% in 1981 in the condition ... | 1987 | 3329988 |
| prophylactic effect of diethylcarbamazine on wuchereria bancrofti filariasis. | 1987 | 3331391 | |
| prophylactic effect of diethylcarbamazine on w. bancrofti filariasis. | 1987 | 3333774 | |
| control of bancroftian filariasis in a rural area through selected treatment with diethylcarbamazine. | 1987 | 3333775 | |
| laboratory parameters in early and late cases of bancroftian filariasis in an endemic area. | 1987 | 3333778 | |
| characterization of stage-specific antigens of infective larvae of the filarial parasite brugia malayi. | three stages of the filarial parasite brugia malayi (infective third stage larvae, adult worms, and microfilariae) were analyzed for differences in their protein composition by two-dimensional gel electrophoresis. comparison of protein profiles of the different stages showed both identical polypeptides (reflecting common proteins) and polypeptides specific for each stage. three polypeptides present only in infective stage larvae were seen at 72 kda at an isoelectric point (pi) of 4.98 (p72), 30 ... | 1988 | 3346549 |
| characterization of a monoclonal antibody against infective larvae of brugia malayi. | monoclonal antibodies were produced following immunization of mice with live infective larvae of brugia malayi. one of these, 46.08.76, is an antibody that promotes adherence of mouse peritoneal macrophages and human peripheral blood leucocytes to the infective larvae of b. malayi and wuchereria bancrofti, respectively, and kills them. fresh normal serum, as a source of complement, augments this effect. the same monoclonal antibody conferred 89% protection to jirds (meriones unguiculatus) agains ... | 1988 | 3384450 |
| microfilarial surface carbohydrates as a function of developmental stage and ensheathment status in six species of filariids. | the lectin-binding properties of microfilariae of onchocerca volvulus, o. lienalis, brugia pahangi, wuchereria bancrofti, dirofilaria immitis, and monanema (= ackertia) marmotae share a number of characteristics. carbohydrates specific for lectins are associated with the egg shell or sheath. n-acetyl-d-glucosamine is the predominant carbohydrate associated with the ensheathed forms with lesser quantities of d-galactose and/or alpha-lactose and d-galactosamine. the density of these carbohydrates ... | 1988 | 3418456 |
| microfilariae in fine needle aspirates from epididymal lesions. | microfilariae of wuchereria bancrofti were observed in fine needle aspiration smears from three epididymal nodules, and degenerating microfilariae suggestive of brugia malayi were found in the smears from a fourth case. the smears in all four cases showed a polymorphonuclear inflammatory cell component as well as epithelioid cell granulomata. while blood eosinophilia was present in all four cases, eosinophilia was present in the aspiration smears in only one case. microfilariae could be demonstr ... | 1987 | 3468719 |
| pathogenesis of lymphatic filariasis in man. | 1986 | 3515791 | |
| [bancroftian filariasis in french polynesia. epidemiologic status and perspectives after a 35-year preventive campaign]. | the authors assess of three decades of struggle against bancroftian filariasis in french polynesia. wuchereria bancrofti var. pacifica, aperiodic filaria, and aedes polynesiensis, mosquito with high parasitologic output, set up a cycle very well adapted to the polynesian environment; after numerous tests, the chemoprophylaxis with diethylcarbamazine (3 mg/kg/half-year) of all the exposed population has been decided, in association with methods of vector-control (use of predatory crustaceans). ho ... | 1986 | 3516427 |
| control of bancroftian filariasis by salt medicated with diethylcarbamazine citrate. | 1986 | 3517181 | |
| identification of brugia malayi in vectors with a species-specific dna probe. | we evaluated the potential value of a cloned sequence of genomic dna of brugia malayi as a species-specific probe. clone pbm 15 reacted with all stages of 8 different geographic isolates of b. malayi and cross-hybridized with microfilariae of b. timori. it did not hybridize with wuchereria bancrofti or with b. pahangi, w. kalimantani, dirofilaria repens, breinlia booliati or cardiofilaria species, animal filariids that can be sympatric with b. malayi. p32-labeled clone pbm 15 correctly identifie ... | 1986 | 3518507 |
| detection of circulating parasite antigen in bancroftian filariasis by counterimmunoelectrophoresis. | we used counterimmunoelectrophoresis (ciep) with rabbit antibodies to dirofilaria immitis and brugia malayi to detect soluble filarial antigen in sera collected in a wuchereria bancrofti-endemic area in south india. filarial antigen was detected in 38 of 38 sera from microfilaremic patients, 3 of 48 sera from amicrofilaremic patients with lymphatic pathology, and 3 of 5 sera from former microfilaria carriers with negative blood examinations 6 months or more after diethylcarbamazine therapy. one ... | 1986 | 3518508 |
| secreted and surface antigens from larval stages of wuchereria bancrofti, the major human lymphatic filarial parasite. | antigenic proteins of microfilariae and infective larvae of wuchereria bancrofti have been identified by intrinsic and extrinsic radiolabelling, and specific immunoprecipitation with sera from filarial patients. from 125i surface-labelling experiments, the most prominent antigen on both stages is of relative molecular mass (mr) 17 000, while a molecule of similar size is both synthesized and released in vitro following labelling with [35s]methionine. a second similarity between the two stages is ... | 1986 | 3520311 |
| [value of a papain-treated homologous microfilarial antigen in the diagnosis of filariasis due to wuchereria bancrofti var. pacifica. analysis of 237 cases]. | an indirect immunofluorescence assay using papaïn treated microfilariae (ifi-wbp) has been performed to attempt diagnosis of bancroftian filariasis. the authors have analysed 237 bed-rests of patients consulting for specific and non specific lymphangitis, chyluria, elephantiasis, hydrocele or just asymptomatic hypereosinophilia. taking into account the clinical aspects, the parasitological and the serological results, they have shown the efficiency of ifi-wbp (titre greater than 80) to diagnose ... | 1986 | 3523109 |
| vectors of wuchereria bancrofti in the sepik provinces of papua new guinea. | the vectors of wuchereria bancrofti were investigated in two areas of the sepik provinces of papua new guinea. at the village of yauatong, indoor-resting anopheles punctulatus had an infection rate of 47.3% and an infective rate of 3.4%. no infections occurred in 382 culex annulirostris obtained in night-landing catches. at the village of yankok only an. koliensis contained infective larvae but an. punctulatus and cx quinquefasciatus were infected. probit values of the cumulative percentages of ... | 1986 | 3523861 |
| [bancroft's filariasis in anjouan (comoro islands)]. | a parasitological survey on bancroftian filariasis has been carried out in anjouan (comoro islands) in 1982. a fall in the microfilaria rate (17.66%) is noticeable comparatively to prod'hon investigations in 1969 (41.25%). prevalence is reduced in the main localities but is still high in remote villages, specially in the inner district of the island. | 1986 | 3524880 |
| relative effect of mass survey and selective survey in mass diethylcarbamazine treatment. | 1986 | 3528276 | |
| [comparative estimate of the rates of infection with sporozoites and filaria in various forms of the anopheles gambiae complex in a village in mali]. | 1986 | 3530084 | |
| [wuchereria bancrofti: value of the diethylcarbamazine provocation test for the diurnal detection of microfilaria carriers]. | sixty-nine of 83 (83%) patients with circulating microfilariae of nocturnally periodic wuchereria bancrofti were detected in daytime blood films following the one-time administration of diethylcarbamazine at a dose per patient of 1 +/- .25 mg/kg of body weight. this method of detecting microfilaria carriers in haiti is recommended as a reasonably sensitive alternative when circumstances make it impossible to conduct a nighttime blood survey. | 1986 | 3533297 |
| genital filariasis in minnesota. | genitourinary filariasis is a well-known entity in most tropical areas. however, filariasis cannot be eliminated from the differential diagnosis of testicular, epididymal, or spermatic cord masses in nontropical climes. we report a case of filariasis of the spermatic cord that manifested as an unexplained scrotal mass in a patient in rochester, minnesota. | 1986 | 3538615 |
| coexistent metastatic malignant melanoma cells and wuchereria bancrofti microfilariae in urinary sediment. | 1986 | 3538734 | |
| the status of human filariasis in relation to clinical signs in endemic areas of the niger delta. | a study was carried out in selected parts of the niger delta basin on human filariasis and its relationship to clinical signs. one hundred and seventy-six (13.0%) of 1351 individuals examined were infected with microfilaria. forty-six percent of microfilaria positive cases had m. perstans; 25.6% had w. bancrofti, 19.3% had l. loa, and 9.0% had o. volvulus. the prevalence of filariasis increased with age. microfilarial density was generally low, 28.4% of infected individuals had counts of 50-100 ... | 1986 | 3539045 |
| [chorio-retinal involvement in a patient with lymphatic filariasis]. | 1986 | 3539247 | |
| antigenic characterization of adult wuchereria bancrofti filarial nematodes. | adult wuchereria bancrofti were recovered from infected presbytis cristatus monkeys and radio-isotope labelled extrinsically with 125i and in vitro with [35s]methionine. 125i labelling of the surface of adult w. bancrofti permitted a comparison between the major surface antigens of this species and those from the related lymphatic filariae, brugia malayi and b. pahangi. all species bear a prominent mr 29,000 surface antigen but among the differences observed were the strongly labelled molecules ... | 1986 | 3540817 |
| differentiation of infective larvae of brugia malayi and wuchereria bancrofti by scanning electron microscopy. | a comparative scanning electron microscopy of the infective (third stage) larva of wuchereria bancrofti and brugia malayi revealed the following features: the lateral caudal papillae in both species are rounded and the terminal papilla is relatively pointed and smaller. the caudal papillae in w. bancrofti are more protruding while in b. malayi they are flattened. the lateral caudal papillae in b. malayi have an indentation around their bases which is absent in w. bancrofti. this is the most usef ... | 1986 | 3541808 |
| [comparison of heterologous adult filarial antigens in detecting serum antibodies in bancroftian filariasis patients by indirect fluorescent antibody test]. | 1986 | 3542280 | |
| disc/stick elisa for diagnosis of bancroftian filariasis. | 1986 | 3546104 | |
| isolation and evaluation of antigens from microfilaraemia plasma and immune complexes for diagnosis of bancroftian filariasis. | 1986 | 3546110 | |
| [lymphatic filariasis in haiti: historical sequel or future public health problem in this geographic region?]. | wuchereria bancrofti persists in haiti in localized foci, discontinuously distributed. the parasite, transmitted by culex quinquefasciatus, develops in mesoendemic or hyperendemic fashion in urban and suburban areas, on the coastal plains sheltered from the prevailing winds, predominantly in the nord department and around the gulf of la gonave. lymphatic filariasis is a major public health problem. its impact is more evident in males on account of the genital repercussion of the disease. the acu ... | 1986 | 3549024 |
| [epidemiology of filariasis (onchocerciasis and bancroftosis) in the tala-mokolo region (mandara mountains of north cameroon)]. | the effect of the bancroftian filariasis on the health of the inhabitants are minimal in the study area, where the prevalence of the disease (nocturnal microfilaremia) is 0.4% only. but skin snips harboring onchocerca microfilariae are seen in 12.1% of the sample studied. onchocerciasis skin lesions, low visual acuity and blindness are often seen in the villages where the prevalence is high, among inhabitants more than 40 years of age. simulium damnosum is seldom seen in the area, except in the ... | 1986 | 3549025 |
| problems in filariasis control and the need for human behaviour and socio-economic research. | 1986 | 3551094 | |
| filariasis in mirpur area of dhaka city. | 1986 | 3551910 | |
| [use of elisa to the diagnosis and seroepidemiological survey of filariasis]. | 1986 | 3552293 | |
| parasite-specific anergy in human filariasis. insights after analysis of parasite antigen-driven lymphokine production. | the antigen-specific immune unresponsiveness seen in bancroftian filariasis was studied by examining lymphokine production in peripheral blood mononuclear cells (pbmc) or pbmc subpopulations from 10 patients with asymptomatic microfilaremia, 13 patients with elephantiasis and 6 normal north americans. in each group of patients, the kinetics of the lymphokine response and the response to mitogens and nonparasite antigens did not differ significantly. in marked contrast, when antigen-induced lymph ... | 1987 | 3553242 |
| lymphatic filariasis: in vitro lymphoproliferation in wuchereria bancrofti infection. | 1986 | 3553312 | |
| identification and partial characterization of a parasite antigen in sera from humans infected with wuchereria bancrofti. | the purpose of this study was to identify and characterize soluble parasite antigens present in sera from humans infected with the filarial nematode wuchereria bancrofti. affinity chromatography and immunoblot methods were used to demonstrate a 200,000 m.w. circulating parasite antigen in sera from infected humans which corresponded to an antigen released by adult w. bancrofti during in vitro culture. two monoclonal antibodies were produced to this antigen by immunizing mice with antigens from d ... | 1987 | 3553330 |
| attempt to culture wuchereria bancrofti in vitro. | third-stage larvae of wuchereria bancrofti recovered from laboratory raised aedes togoi and anopheles maculatus fed on a human volunteer were recovered by mass dissection methods and introduced into in vitro culture. llc-mk2 cells were used as feeder cells, and the culture medium consisted of rpmi-1640 buffered with hepes and sodium bicarbonate and supplemented with human ab serum. the third-stage larvae molted as early as 12 days and those surviving had all molted by 16 days. the fourth-stage p ... | 1986 | 3554544 |
| parasite antigens in sera and urine of patients with bancroftian and brugian filariasis detected by sandwich elisa with monoclonal antibodies. | we developed a sandwich enzyme-linked immunosorbent assay to detect circulating parasite antigens in human lymphatic filariasis. the assay utilizes a polyclonal rabbit antifilarial antiserum to capture, and a monoclonal antibody to identify, circulating parasite antigen. using this assay, we found that greater than 95% of sera from microfilaremic donors with bancroftian or brugian filariasis, approximately 60% of sera from microfilaremic patients with hydroceles, chyluria, or elephantiasis, and ... | 1987 | 3555138 |
| immunochemical characterization and biosynthesis of major antigens of iodo-bead surface-labeled brugia malayi microfilariae. | the objectives of the present study were to identify and characterize biochemically the major antigens of brugia malayi microfilariae, a filarial parasite that infects humans. igg antibodies in sera of mice which had cleared parasites from the bloodstream reacted with 30, 55, 94 and 150 kda molecules of living microfilariae radioiodinated by the iodo-bead method. sera of humans infected with the related filariae wuchereria bancrofti, loa loa or onchocerca volvulus immunoprecipitated molecules of ... | 1987 | 3574345 |
| the cat infected with brugia pahangi as a model of human filariasis. | the responses of cats to brugia pahangi, which parasitizes them in nature, mimic those of humans to brugia malayi and wuchereria bancrofti in many important respects. it is likely that many of the features of the relationship between host and parasite that can be studied in cats infected with b. pahangi also apply to humans, but for a variety of practical reasons cannot be demonstrated in humans. both immunologically and parasitologically there is a profound difference between b. pahangi-infecte ... | 1987 | 3595322 |
| characterization of an onchocerca-specific dna clone from onchocerca volvulus. | a genomic library of a savanna isolate of onchocerca volvulus was screened to detect recombinant plasmids containing highly repeated dna sequences of this parasite. four recombinant plasmids were identified which hybridized specifically to onchocerca dna, but not to dna from humans, black flies, brugia malayi, b. pahangi, or wuchereria bancrofti. the recombinant plasmids had a low level of homology to dirofilaria immitis. all recombinant plasmids contain related dna sequences based on southern h ... | 1987 | 3661830 |
| [filariasis bancrofti]. | 1985 | 3883568 | |
| chronic chyluria: a clinical study of 3 patients. | studies of patients with chyluria or chylothorax have demonstrated significant disruptions of protein, blood and fat metabolism that may result in iron deficiency anemia, hypoproteinemia, hypolipidemia and malnutrition. to document the sequential development of these complications we performed serial clinical and biochemical studies for 2 to 12 years in 3 patients with presumed filarial chyluria whose sole treatment had been diethylcarbamazine. despite the chronic loss of chyle in the urine thes ... | 1985 | 3884843 |
| wuchereria bancrofti in a haitian immigrant. | a case of wuchereria bancrofti filariasis was recently seen in a haitian immigrant in charleston, sc. the caribbean area is a known endemic focus for this organism. with the increased numbers of immigrants from that area, it is likely that other such cases will be seen in the us. | 1985 | 3885410 |