Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [larval toxocariasis in a 40-year-old man with detection of larvae in a liver biopsy]. | a 40-year old cattle feeder has been suffering from indigestion, leukocytosis and conspicuous eosinophilia for about 4 years. a sample of liver tissue was taken during gastrectomy and multiple allergic granulomas rich in eosinophilia leukocytes were found. toxocara canis was identified in serial sections outside the granulomas. larval toxocariasis was confirmed by a high level of specific antibodies which failed to decrease even after administration of mintezol antithelmintic. in this country, t ... | 1983 | 6661784 |
| some observations on the experimental infection of white mice with toxocara canis. | 1983 | 6663101 | |
| the iga antibody activities in relation to the parasitologic status of toxocara canis in dogs. | in this study, the relationship between the iga antibody activities to toxocara canis infection in dogs and their parasitologic status has been examined. the enzyme-linked immunosorbent assay was applied to the sera of dogs for the detection of the specific iga antibodies and at the same time, autopsy and stool examination were performed on these dogs. the most elevated iga antibody levels were observed in the one-month age group of puppies. thereafter, the levels gradually decreased until six a ... | 1983 | 6673418 |
| preliminary study on the follow-up observations of the antibodies and circulating antigens in canine toxocariasis. | in the sera of dog fetuses and newborn puppies, no antibody to toxocara canis was found but an elevation of the circulating toxocaral antigens (cta). in the mother dogs, detectable igg and igm antibodies were found. the igg antibodies gradually increased in the course of this observation. the most elevated levels of iga antibodies were observed one month after birth. the same was true for the cta levels. there was no placental transfer of the antibodies nor could they be transferred from the mot ... | 1983 | 6673419 |
| the measurement of ascaris suum protein by radioimmunoassay in sera from patients with helminthiasis and with gastrointestinal diseases. | in this study, we have developed a reliable radioimmunoassay (ria) for ascaris suum protein (asp) and have measured the serum concentration of asp in control subjects and in patients with helminthiasis and a variety of gastrointestinal diseases. the cross-reactivities of asp antibody with other helminth worm antigens were also measured by ria. ascaris lumbricoides contained approximately the same amount of asp antigenic substance as did ascaris suum. toxocara canis had a high concentration of a ... | 1983 | 6682964 |
| activation of complement in c-reactive protein positive sera by phosphorylcholine-bearing component isolated from parasite extract. | phosphorylcholine-bearing component levels in extracts of various parasites were determined by a capillary precipitin test using anti-phosphorylcholine ig a myeloma protein. tepc-15. phosphorylcholine was demonstrated as a structural component not only in nematodes but also in trematodes and cestodes. the phosphorylcholine-bearing component was isolated from an extract of toxocara canis larvae using a tepc-15-sepharose 4b column. the component reacted with c-reactive protein in sera to form one ... | 1983 | 6684760 |
| experimental ocular toxocariasis: a mouse model. | male mice, strain c57 black, were infected with toxocara canis by a single intragastric dose of 1500 infective eggs. the eyes were studied at sequential time periods after infection (6 to 63 days) by conventional microscopic techniques, and the histological characteristics of the inflammatory response were recorded. in the majority of animals the disease was unilateral. twenty-six larvae were found in the retina, in the retinal vessels, and in the subretinal space in 20 eyes, while in 29 eyes th ... | 1984 | 6691961 |
| toxocara canis infection of the eye. correlation of clinical observations with developing pathology in the primate model. | a primate model for the study of toxocara canis infection was created by intravitreal, periocular, systemic, and intracarotid injection of viable larvae in cynomolgus monkeys. the results were as follows: (1) intravitreal larvae caused retinal hemorrhages, perivasculitis, mild vitritis, and retinal nodules. (2) apparently viable larvae without inflammatory reaction were found in the vitreous, retina, and optic nerves up to nine months after intravitreal inoculation. (3) other larvae were surroun ... | 1984 | 6696677 |
| characterization of surface and excretory-secretory antigens of toxocara canis infective larvae. | the surface antigens of toxocara canis infective larvae have been identified by radio-iodination and compared with the excretory-secretory (es) products released by the larvae in vitro. common antigens, of molecular weight 32 000 and 120 000 are found on the larval surface, in the es material and in culture supernatant following surface iodination of living t. canis larvae. the 120 000 antigens consist of three closely migrating bands in each of these preparations. however, one prominent es comp ... | 1984 | 6701003 |
| anthelmintic effect of febantel/praziquantel paste in dogs and cats. | a paste formulation of 3.4% febantel and 0.34% praziquantel was given in soft food at a rate of 0.29 g/kg of body weight, once daily for 3 days to dogs and cats. eleven of 12 dogs were naturally infected with ancylostoma caninum, 10 with trichuris vulpis, 2 with toxocara canis, 5 with taenia sp, and 3 with dirofilaria immitis. ten of 11 cats were naturally infected with toxocara cati, 2 with ancylostoma tubaeforme, 3 with taenia sp, 5 with capillaria aerophila, and 1 with paragonimus kellicotti. ... | 1984 | 6703448 |
| toxocara canis infection: clinical and epidemiological associations with seropositivity in kindergarten children. | to determine epidemiological and clinical associations with toxocara canis seropositivity, we studied 333 (87%) children of a cohort of 383 five- to seven-year-olds. the prevalence of seropositivity (antibody titer to t canis, greater than or equal to 1:32) was 23.1%. black children were more frequently seropositive than were white children, as were children of parents who did not graduate from high school. in a sample of seropositive and seronegative children, seropositivity was associated with ... | 1984 | 6725991 |
| metazoan parasites of dogs in sabah, malaysia. | the parasites which occurred most frequently in 175 owned or stray dogs in sabah were ancylostoma spp. present in 68% of the animals. dirofilaria immitis occurred in 70% of the adult dogs but neither d. immitis nor spirocerca lupi were present in puppies under four months of age. the latter attained a prevalence of 30% in the adults. in contrast toxocara canis occurred in 81% of the puppies but infrequently in older dogs. dipylidium caninum was moderately prevalent (15 to 25%) in dogs of all age ... | 1984 | 6730003 |
| helminth parasites of wild foxes (vulpes vulpes l.) in the netherlands. | to study the helminth fauna of wild foxes (vulpes vulpes) in the netherlands, material was collected from 139 foxes. the following parasites were found. cestodes: taenia spp. 53.3%, hymenolepis spp. 1.5%; trematodes: alaria alata 10.9%, cryptocotyle lingua 3.6%, euparyphium melis 1.5%, apophallus donicus 0.7%; nematodes: toxocara canis 73.7%, uncinaria stenocephala 59.9%, capillaria aerophila 46.8%, c. plica 23.5%, molineus patens 5.1%, crenosoma vulpis 4.5%, strongyloides spp. 0.7%. the tapewor ... | 1984 | 6741217 |
| toxocara antigen and mitogen-induced lymphocyte blastogenesis for diagnosis of visceral larva migrans: clinical and experimental findings in macaques and human beings. | peripheral lymphocytes from macaques inoculated with toxocara canis and from children with serologically confirmed visceral larva migrans (vlm) were assayed for blastogenic responses using toxocara antigen and standard mitogens. macaques were given single or multiple larval infections. lymphocyte responses of inoculated macaques were compared with responses from noninoculated macaques. similarly, lymphocyte responses from 2 serologically confirmed human toxocara vlm patients were compared with t ... | 1984 | 6742587 |
| [ocular toxocariasis. diagnostic and therapeutic attainments]. | toxocara canis is nematode parasite of dogs. children are particularly subject to infestation, however the larva remains quiescent at stage ii. toxocara can localize in the eye and induce a variety of clinical manifestations. a case of ocular toxocara is presented in which there was granulomatous endophthalmitis. immunologic testing was negative in the serum but positive in the vitreous, where numerous eosinophils and plasma cells where found. vitreous and aqueous ige levels were elevated. corti ... | 1984 | 6747214 |
| toxocara canis infection in dogs in beersheba, israel. | in the desert city of beersheba, israel, a survey was made of the infection rate of toxocara canis in dogs. 3.0% of dogs destroyed at the municipal dog pound had intestinal t. canis. 7% of faecal samples gathered from day care centres throughout the city were shown to contain t. canis eggs. this low rate of infection could possibly be explained by the hot, arid climatic conditions which may render eggs non-infective or by the sandy soil in the area that may cover faeces containing t. canis ova a ... | 1984 | 6747256 |
| induction of peripheral blood eosinophilia in mice by excretory and secretory antigen of toxocara canis larvae. | medium in which t. canis larvae had been cultured was applied to a sephadex g-25 gel column and four fractions (fr. 1-fr. 4) were isolated. each fraction was administered to mice by implanting a mini-osmotic pump into the peritoneal cavity and the subsequent peripheral blood eosinophilic counts were recorded. mice given fr. 1 showed a markedly greater eosinophilic response than did those given the other fractions. complement activation by each fraction was investigated using normal human serum. ... | 1984 | 6747257 |
| the use of an excretory-secretory antigen for an elisa specific sero-diagnosis of visceral larva migrans. | in sera from patients with visceral larva migrans (vlm) syndrome, enzyme-linked immunospecific assay (elisa) was used to detect igg and ige antibody anti-excretory-secretory antigen (esa) from the second larval stage of toxocara canis. the technical conditions of the assay were determined. the specificity of igg elisa-esa (with od values greater than 0.34) allowed the differentiation of vlm syndrome from ascaris or other human parasite infections. | 1982 | 6751420 |
| serologic diagnosis of toxocara canis infection. | visceral larval migrans (vlm) caused by toxocara canis presents a wide spectrum of clinical manifestations with eosinophilia. although the presence of increased serum ige and isohemagglutinin titers are useful screening tests, the specific diagnosis rests on identification of larvae in biopsy specimens of tissues or serologic tests for specific antibody to the toxocara organism. a 2-year-old boy with marked eosinophilia associated with milk respiratory tract illness had negative indirect hemaggl ... | 1980 | 6768136 |
| work in progress: radionuclide imaging of indium-111-labeled eosinophils in mice. | eosinophils isolated from peritoneal exudates were labeled with indium-111-oxine and injected intravenously into sensitized mice. they became localized at sites of inflammation produced by intradermal injections of schistosomal antigen or toxocara canis larvae, whereas labeled neutrophils did not. intense uptake of eosinophils by normal spleen, liver, and bone marrow was noted, with tracer distribution effectively complete by 5 hours after injection. indium-111-eosinophil studies appear to be qu ... | 1983 | 6836137 |
| visceral larva migrans: examinations by means of enzyme-linked immunosorbent assay of human sera for antibodies to excretory-secretory antigens of the second-stage larvae of toxocara canis. | an enzyme-linked immunosorbent assay is described for the detection of serum antibodies to visceral larva migrans (toxocariasis). excretory-secretory antigens of the second-stage larvae of toxocara canis were used as antigen to coat the polystyrene plates. with sera from patients high antibody titers were observed in both ocular and visceral disorders. cross-reactions due to other parasitic infections could be excluded, including other migrating larval infections such as ascariasis, trichinellos ... | 1983 | 6837095 |
| cytosolic malate dehydrogenase in muscle extracts of toxocara canis. | 1. malate dehydrogenase (l-malic acid:nad+ oxydoreductase, ec 1.1.1.37) was partially purified from muscle extracts of toxocara canis by means of gel chromatography in sephadex g-150 and affinity chromatography in sepharose-4b-blue dextran. 2. the purified enzyme was very active in reducing oxalacetate and less active in oxidizing l-malate. it was inhibited by excess oxalacetate but not by l-malate. 3. the kinetic parameters of the enzyme were obtained and these included: ph and temperature opti ... | 1983 | 6851482 |
| neuropathological studies of experimental toxocariasis in lead exposed mice. | binghamton heterogeneous stock mice intubated with embryonated eggs from the common parasite of dogs, toxocara canis, display dramatic alterations in behavior. many of these behavioral changes are markedly attenuated if mice are maintained also on a drinking solution containing lead acetate. the data presented here, however, show that the extensive neural degeneration of the cns occurs after t. canis infection and that the nature and extent of this degeneration is similar, regardless of whether ... | 1983 | 6860979 |
| [eosinophilic infiltrate with reference to toxocara canis. apropos of a case in an adult]. | larva migrans syndromes are rare affections that occur mainly in young children. the usual parasite involved is toxocara canis, its presence in humans leading to encystment of the larvae and an eosinophilic granulomatous reaction. a case of an adult with this affection is reported, and clinical aspects and diagnostic and therapeutic problems discussed. | 1983 | 6878113 |
| determination of the specific gravity of certain helminth eggs using sucrose density gradient centrifugation. | the specific gravities of ten species of helminth eggs were determined using sucrose density gradient centrifugation. fecal or egg concentrate was layered over a 3 to 54% sucrose density gradient. the gradient was then centrifuged at 800 g for 20 min, allowing 5 min for acceleration and 5 for deceleration. bands formed were identified and measured. refractive index was measured at the middle of narrow bands, or at the level at which the concentration of eggs was highest, in the case of wide band ... | 1982 | 6890102 |
| survival rates of parasite eggs in sludge during aerobic and anaerobic digestion. | the effects of mesothermic anaerobic or aerobic sludge digestion on survival of eggs from the roundworms ascaris suum, toxocara canis, trichuris vulpis, and trichuris suis and from the rat tapeworm hymenolepis diminuta were studied. destruction of eggs throughout a 15-day treatment period, as well as their viabilities after reisolation, was analyzed. the laboratory model digesters used in this study were maintained at a 15-day retention schedule, partially simulating a continuously operating sys ... | 1982 | 6891199 |
| activity of ivermectin against canine intestinal helminths. | the anthelmintic activity of ivermectin was tested in 98 dogs against adult ascarids (toxocara canis, toxascaris leonina), hookworms (ancylostoma caninum, a braziliense), and whipworms (trichuris vulpis), and against experimentally induced infections (4th-stage larvae) of t canis and a caninum. dosage levels tested were single subcutaneous injections of 50, 100, 200, or 400 micrograms/kg of body weight with appropriate vehicle-treated controls. a minimum of 4 (usually 5) dogs were tested with ea ... | 1982 | 6897345 |
| toxocariasis in an institution for the mentally retarded. | a seroepidemiologic investigation was conducted in order to determine the cause of an apparent increase in rates of eosinophilia among 1400 institutionalized children during 1976-1977. the annual serologic survey during this period revealed 283 (20%) individuals with eosinophilia that exceeded 600 cells/cu mm of blood. during a five-month period in 1977, five patients who were hospitalized in adjacent wards developed acute pneumonia with eosinophilia. because laboratory tests of sputum, bone mar ... | 1981 | 6912220 |
| toxocara canis: the risks of infection. | 1980 | 6928062 | |
| [roundworm infection (toxocara and toxascaris) in dogs in the netherlands (author's transl)]. | the incidence of roundworm infections was determined by examination of the faeces in a total number of 544 adult dogs in the netherlands during the period from 1972 to 1977. the incidence of roundworm infections varied from 13 to 34 per cent (average 22.9 per cent) during this period, from 2 to 31 per cent (average 14.5 per cent) for toxocara canis infections, from 8 to 15 per cent (average 11.2 per cent) for toxascaris leonina infections and from 0 to 11 per cent (average 2.8 per cent) for comb ... | 1980 | 6929575 |
| toxocara canis: t lymphocyte function in murine visceral larva migrans and eosinophilia onset. | 1980 | 6965279 | |
| eosinophilia, granuloma formation and migratory behaviour of larvae in the congenitally athymic mouse infected with toxocara canis. | peripheral blood eosinophilia, histology of skeletal muscle and brain, and larval recovery were compared between congenitally athymic nude mice (nu/nu) and thymus-bearing heterozygous littermates (nu/+) for 6 weeks following oral infection with toxocara canis eggs. by comparing patterns of peripheral blood eosinophil levels in nu/+ and nu/nu, two types of eosinophilias, one t cell dependent and the other independent, were observed. eosinophil infiltration and granuloma formation around larvae in ... | 1982 | 6983050 |
| field trials with nitroscanate against cestodes and nematodes in dogs. | clinical trials were carried out to test the safety and efficacy of the anthelmintic, nitroscanate, against naturally acquired helminth infections. the trials involved 418 dogs, of which 252 were treated with one or other of two different tablet formulations of nitroscanate. a coarse particle formulation given in two doses each of 200 mg per kg reduced the worm burden of taenia spp and dipylidium caninum by 100 per cent and echinococcus granulosus by 94.1 per cent in farm dogs. given as a single ... | 1980 | 6990596 |
| prevalence of toxocara canis in babies and in adults as determined by the elisa test. | 1980 | 7020214 | |
| [effect of various benzimidazole carbamates on somatic larvae of ancylostoma caninum ercolani 1859 (ancylostomidae) and toxocara canis werner 1892 (anisakidae). 3. immunofluorescent serological studies of antibody levels in treated and untreated dogs]. | 1981 | 7027683 | |
| [serological differentiation of ascaris suum and toxocara canis infections in pigs (author's transl)]. | groups of eight miniature pigs were infected either with 1,500 embryonated eggs each of ascaris suum or toxocara canis or with 1,000 eggs each of both nematodes. sera were sampled before the infection as well as three and six weeks postinfection and then investigated in the elisa on microtitre plates against antigens of various developmental stages. when extracts of adult ascaris and toxocara worms were used as antigens, distinct reactions were registered both in the infected and in the uninfect ... | 1981 | 7032103 |
| [serological demonstration of experimental round worm infections-ascaris suum, toxocara canis--in swine by means of the indirect immunofluorescence antibody test]. | by means of indirect immunofluorescent antibody reaction (ifar), using serum of experimentally infected pigs, various antigens were studied with regard to their usefulness for serological verification of prepatent ascaris suum and toxocara canis infections. eggs, egg larvae, larvae received from livers, lungs and brains of experimentally infected white mice and sections of adult t. canis as well as eggs, egg larvae, liver larvae and sections of frozen adult a. suum proved to be not suitable for ... | 1981 | 7039425 |
| [toxocara canis as a cause of visceral larva migrans. survival and development of eggs in the environment and potential ways of transmission to man: a review]. | a review is given on the occurrence of toxocariasis, the prevalence of t. canis among dogs and investigations on the prevalence of infective ova in soil- and sandsamples. the resistance of ascarid eggs and larvae against different environmental influences, including various sewage treatment-effects is discussed. the eggs are destroyed in 7 minutes when kept at 55 degrees c in a high humidity, slower when the humidity is lowered. when the temperature is -32 degrees c t. canis eggs are inactivated ... | 1982 | 7043391 |
| development of the serological response in rabbits infected with toxocara canis and toxascaris leonina. | the indirect fluorescent antibody test using frozen sections of infective toxocara canis and toxascaris leonina eggs, and the enzyme linked immunosorbent assay using homogenized toxocara canis embryonated egg extract and t canis excretory-secretory products as adsorbed antigens were used to determine the specificity and development of circulating antibodies in rabbits. frozen sections were subdivided into four morphologically distinct compartments for analysis of the development of the circulati ... | 1982 | 7043808 |
| evaluation of granulated fenbendazole as a treatment for helminth infections in dogs. | a granulated formulation of fenbendazole was tested in 95 dogs harbouring naturally occurring infections of toxocara canis, ancylostoma caninum, trichuris vulpis, dipylidium caninum, and taenia spp and in 19 laboratory-reared beagle pups experimentally infected with toxascaris leonina. the drug was administered in moistened dry dog food or in canned dog food. in dosage titration and confirmational studies, using worm counts in naturally infected dogs, the drug was 98%-100% effective at a dosage ... | 1982 | 7056663 |
| parasitological investigation of children's sand boxes and dog faeces from public areas in old housing districts of prague. | eggs and oocysts of 11 species of parasites were recorded in 21 of 50 sand boxes (200 samples) and in 66 (13.2%) of 500 dog faeces samples from parks and grassy areas in prague. toxocara canis was found in 12 sand boxes and in 4.2% of faeces samples and t. cati in one sand box and one sample of dog faeces. | 1982 | 7061019 |
| [toxocariasis in childhood. visceral larva migrans syndrome (author's transl)]. | a case of toxocariasis in a 2(6)/12 years old boy is described. the visceral larva migrans syndrome usually is seen in preschool children. clinical symptoms were characterised by eosinophilia of more than 30%, leukocytosis, hepatomegaly, pulmonary infiltrations, and hypergammaglobulinaemia. there may be myocardial, ocular or central nervous system involvement, and a few affected children have died. the disease is caused by invasion of the body tissues by toxocara canis or cati larvae, often inge ... | 1982 | 7062927 |
| the intestinal helminths of the red fox and some other carnivores in southwest germany. | in south-west germany between 1975 and 1980, 3,573 red foxes (vulpes vulpes), 84 badgers (meles meles), 47 stone martens (martes foina), and 387 cats (felis catus) were examined for intestinal helminths. in foxes the extent of infections was: taenia crassiceps 24%, t. polyacantha 8%, t. taeniaeformis 0.6%, t. serialis 0.5%, mesocestoides leptothylacus 20%, mesocestoides sp. 0.2%, toxocara canis 32%, toxascaris leonina 3%, uncinaria stenocephala 26%. one to three foxes harboured t. hydatigena, t. ... | 1982 | 7072323 |
| [the larva precipitation test with ascaris suum and toxocara canis larvae]. | investigations were made by means of a larvae precipitation test (lpt) on different laboratory animals (pigs and white mice, and pigs, rabbits, guinea pigs and white mice respectively) experimentally infected with ascaris suum and toxocara canis respectively for the serological evidence of specific a. suum and t. canis antibodies. living a. suum larvae isolated from the lungs of experimentally infected white mice forming oral, excretion porus and cuticula precipitates proved to be a suitable ant ... | 1982 | 7081762 |
| effect of febantel against ancylostoma caninum and trichuris vulpis infections in dogs. | febantel was administered as a 3.4% paste to 45 dogs infected with 1 or more nematode species, which included ancylostoma caninum and trichuris vulpis. dosage levels of 5, 10, or 15 mg/kg of body weight daily for 3 consecutive days for a total of 15, 30, or 45 mg/kg were administered. at 15 mg/kg, all dogs were completely cleared of all nematode and cestode infections, including a caninum, t vulpis, uncinaria stenocephala, toxocara canis, toxascaris leonina, taenia sp, and dipylidium caninum, ex ... | 1982 | 7103181 |
| the prevalence of dirofilaria immitis and other parasites in urban pound dogs in north-eastern victoria. | the results of a survey investigating the prevalence of dirofilaria immitis and other helminth and protozoan infections in urban dogs in north-eastern victoria are presented. d. immitis was detected in 2.7% of the general population (8.3% of dogs older than 2 years). microfilariae of d. immitis were not detected in the peripheral circulation of 30% of dogs infected with the adult parasites. the most prevalent gastro-intestinal parasites were dipylidium caninum 57%; trichuris vulpis 41%; toxocara ... | 1982 | 7115227 |
| [visceral toxocara canis larva migrans]. | 1982 | 7146606 | |
| effects of nematode larvae (trichinella spiralis and toxocara canis) on b-glucuronidase enzyme in experimentally infected mice. | 1982 | 7153552 | |
| astrocytic hamartoma in tuberous sclerosis mimicking necrotizing retinochoroiditis. | a pale, elevated peripapillary lesion discovered in a young child with no family history of phakomatoses, grew larger, caused vitreous hemorrhage and underwent necrosis. secondary inflammation developed in the eye, finally producing rubeosis irides with elevated intraocular pressure and a blind, painful eye which required enucleation. clinically, the lesion was variably diagnosed and treated as toxoplasmosis and toxocara canis. these diagnoses were made despite low titres, a negative elisa test ... | 1982 | 7153823 |
| migration of some roundworm species in experimentally infected white mice. | the migration of four roundworm species (ascaris suum, toxocara canis, t. cati and toxascaris leonina) was studied in various organs of experimentally infected white mice. the hatching of t. leonina and t. cati larvae in the paratenic host is more rapid (24-36 h) than the hatching of a. suum and t. canis larvae (1-6 days). the deposition of larvae in host organs is different in the individual species. maximum number of larvae in the liver: t. leonina and a. suum on day 4, t. canis on day 2 and t ... | 1982 | 7160786 |
| behavioral changes in mice infected with toxocara canis. | 1982 | 7161817 | |
| gastrointestinal helminth parasites of dogs in the western area--freetown (sierra leone). | a survey of faecal samples taken from 1277 dogs in the western area (freetown, sierra leone) revealed an infestation by ancylostoma caninum (46,1%), toxocara canis (13,5%), toxascaris leonina (5,9%), dipylidium caninum (3,8%), and spirocerca lupi (3,5%). sampling was made per rectum. the age of the dogs examined, both male and female, ranged from one month to fifteen years. the clinical picture of the dogs affected is described and methods of treatment are suggested. | 1982 | 7171367 |
| induced toxoplasma gondii, toxocara canis, and isospora canis infections in coyotes. | six littermate laboratory-raised coyotes (no. 1-6) were used to study the transmission of toxoplasma gondii from cats and mice, and toxocara canis and isospora canis from dogs and mice. coyotes 1 and 2 were inoculated orally with 1,000 infective oocysts of the tc-1 strain of t gondii; coyotes 3 and 4 were fed mice infected with tissue cysts of the tc-1 strain of t gondii. eight days after inoculation with t gondii, the same 4 coyotes were exposed to toxocara canis: coyotes 1 and 2 were inoculate ... | 1982 | 7174440 |
| investigation of antibodies against toxocara canis in naturally infected puppies. | a investigation of antibodies against toxocara canis was carried out in 15 naturally infected puppies by enzyme-linked immunosorbent assay. for this, four different antigens --eggs containing second stage larvae, larvae, adult worms and excretory-secretory products of larvae--were used. at the same time, autopsy and fecal examinations were carried out in these puppies. of the samples tested, 11 had adult worms and no eggs in the faeces were found in three puppies. the elisa values against four d ... | 1982 | 7180241 |
| an investigation of variables in a fecal flotation technique. | several variables in a standard vial fecal gravitational flotation technique were investigated. these were the specific gravity of the sodium nitrate flotation solution, duration of flotation and mesh sizes of strainers. the number of eggs which floated and adhered to a coverslip were counted and estimates of the number of eggs remaining in the strained fecal suspension and in the feces trapped on the strainer were made. eggs from hookworms, trichuris vulpis and toxocara canis in feces from dogs ... | 1980 | 7190861 |
| antibody to toxocara canis in the aqueous humor. | the aqueous humor and serum samples of patients with presumed ocular toxocariasis were examined by an enzyme-linked immunosorbent assay (elisa) for antibody to the embryonated egg antigen. using a single dilution (1:8), higher amounts of antibody have been found in the aqueous humor than in the serum samples. antibody was not found in the serum or aqueous humor of patients with retinoblastoma, coats' disease, uveal malignant melanoma, or central retinal artery obstruction. while two patients wit ... | 1981 | 7197150 |
| parasitological investigation of children's sandboxes and dog faeces from public areas of housing development in prague. | two hundred sand samples from 50 children's sandboxes and 500 samples of dog faeces collected in 10 prague housing developments were examined for the presence of parasites. eggs of three helminth species were found in 28% of sandboxes and eggs and oocysts of 10 species of parasites were found in 10.4% of dog faeces. toxocara canis occurred in 9 sandboxes and 3.2% of dog faeces, t. cati in 0.2% of dog faeces. the results from housing developments are compared with those from older estates. | 1982 | 7201949 |
| [larva migrans visceralis (toxocara canis) and the central nervous system (author's transl)]. | 1980 | 7207683 | |
| pica patterns, toxocariasis, and elevated blood lead in children. | blood samples were obtained during a lead screening program from 100 children aged 1-6 years in allegheny county, pennsylvania, to determine whether there was any association between specific forms of pica and infection with toxocara canis, the principal cause of visceral larva migrans in the united states, or elevated blood lead levels. significant associations were found between: 1) feces, soil, or grass pica and toxocara infection; 2) paint or plaster pica and elevated blood lead; and 3) dog ... | 1981 | 7212174 |
| anthelmintic tests on toxocara canis infection in mice. | one hundred and forty mice were infected orally with 1000 embryonated toxocara canis eggs. groups of 10 mice were then treated with high doses of piperazine, mebendazole, oxfendazole, albendazole, fenbendazole and diethylcarbamazine for four days, either immediately after infection or three weeks after infection. the mice were killed three to six weeks after treatment and the number of larvae in the brains and muscles estimated and compared with those in untreated mice. few larvae were recovered ... | 1981 | 7233781 |
| serological response of ascarid-free dogs to toxocara canis infection. | antibodies to toxocara were measured by enzyme-linked immunosorbent assay (elisa) in sera of ascarid-free dogs which had been fed 0, 100 or 10 000 embryonated t. canis eggs. dogs fed 10 000 eggs developed higher titres than those given 100 eggs and larvae failed to complete their migration to the gut. in addition, in dogs given 100 eggs, there was a significant negative correlation between the number of worms in the gut and granulomatous foci in the lung. the data suggest that the elisa is sensi ... | 1981 | 7243347 |
| antibodies to canine helminth parasites in asthmatic and nonasthmatic children. | we studied the prevalence of ige and igg antibodies to toxocara canis and dirofilaria immitis, helminth parasites of dogs, in asthmatic and nonasthmatic children born and raised in hawaii. the serologic pattern of the two groups was found to differ significantly. of the 80 asthmatic subjects, 45.0% had ige antibody and 17.5% igg-precipitating antibody to one or both parasites. in contrast, of the 96 nonasthmatic children studied 7.5% were positive for ige antibody and 31.3% positive for igg anti ... | 1981 | 7251191 |
| [toxocara canis (larva migrans visceralis) from an ophthalmological point of view (author's transl)]. | visceral larva migrans (toxocara canis) is usually a relatively benign disease which is caused by infective second-stage larvae of the common cosmopolitan ascarid of dogs, characterized chiefly by sustained eosinophilia, pulmonary symptoms and hepatomegaly. its severity varies with the number of larvae in the tissue and the immune or allergic state of the infected individual. the most important aspect of the neurotropic larvae perhaps is its potential as a facilitating agent, for instance, for v ... | 1980 | 7253511 |
| behavioral effects of lead and toxocara canis in mice. | adult mice were administered the common parasite toxocara canis or lead or both. the parasite clearly altered mouse performance on tests of exploration, activity, learning, and motor coordination; behavioral effects in mice receiving lead alone were less general. consequence of toxocara administration appeared attenuated in animals receiving both agents. parasite larvae were found in the central nervous system in all infected mice. | 1981 | 7268424 |
| comparative anthelmintic efficacy of two schedules of mebendazole treatment in dogs. | two schedules of anthelmintic oral treatment, using mebendazole powder, were compared in 73 dogs naturally infected with common helminth intestinal parasites. mebendazole powder was administered to 26 dogs at doses of 22 mg/kg once daily for 3 days and was compared with the same dose given only daily for 5 days into 23 dogs. the 24 other dogs were kept as controls and received a placebo treatment for 5 days. efficacy results for the 3-day treatment schedule of mebendazole were as follows: toxoca ... | 1981 | 7271006 |
| [occurrence of toxocara canis and other endoparasites in dogs in west berlin]. | 1981 | 7271732 | |
| toxocara canis and lead alter consummatory behavior in mice. | ingestion of palatable and unpalatable solutions was measured in adult mice in which had been administered the common parasite of the dog, toxocara canis alone, or in combination with lead. in addition, response to hot plate and susceptibility to electroconvulsive seizure were also measured. results from the palatability test indicated that either lead or toxocara may alter the mouse's mode of interacting with its environment. however, the two agents in combination interacted in their effects on ... | 1981 | 7272805 |
| [effect of various benzimidazole carbamates on somatic larvae of ancylostoma caninum ercolani 1859 (ancylostomidae) and toxocara canis werner 1782 (anisakidae). 1. studies in white mice]. | 1981 | 7282180 | |
| [prenatal and galactogenic infections with toxocara canis werner 1782 (anisakidae) in mice]. | 1981 | 7293559 | |
| immunopathology of ascarid infection of the eye. role of ige antibodies and mast cells. | the roles of ige antiascarid antibodies and mast cells were compared in passively sensitized guinea pigs and animals infected intravitreally with ascarid larvae (toxocara canis, ascaris suum). intravenous ige antibody disappeared from the serum within 48 hours, but induced a hypersensitive state that persisted for 28 days. in systemically immunized animals, the aqueous-serum ige antibody ratio was 1:1,000 or less. passive periocular anaphylactic reactions produced an infiltration of neutrophils ... | 1981 | 7295137 |
| [high-grade visual acuity impairment caused by parasite-induced uveoretinitis during toxocara canis infection (author's transl)]. | 1981 | 7321470 | |
| ocular toxocariasis presenting as leukocoria in a patient with low elisa titer to toxocara canis. | a 4-year-old white female presented with leukocoria of the right eye. white punctate lesions were observed posterior to the retrolental membrane, which suggested retinoblastoma of some examiners. a full history, physical examination, ultrasonography, and ct scan failed to rule the diagnosis of retinoblastoma in or out. a serum elisa titer was 1:4, which was considered nondiagnostic. examination of the enucleated eye revealed a midsegment of the second stage larva of toxocara canis. the strengths ... | 1981 | 7322480 |
| the effect of corticosteroid therapy on infection with toxocara canis in dogs. | three, six-month-old dogs were infected with 2,000 eggs of toxocara canis. three weeks after infection 15 immature adult parasites were found in the intestine of the dog which had been treated with high doses of corticosteroids (2 ml of opticortenol s given every four days) while no parasites were found in the intestine of the dog treated with repeated injections of 0.3 ml opticortenol s or in the untreated control dog. the increased susceptibility to infection with t. canis in the dog treated w ... | 1981 | 7324542 |
| [behavior of toxocara canis werner 1782 (anisakidae) larvae during and following lung migration in the definitive host (beagle)]. | 1981 | 7324639 | |
| the effect of temperature and antimetabolites on antibody binding to the outer surface of second stage toxocara canis larvae. | in vitro maintained second stage toxocara canis larvae do not bind antiserum raised to their excretions and secretions (es) at 37 degrees c as detected by indirect fluorescence. however, when these larvae were incubated at 2 degrees c under the same conditions intense fluorescence on the whole outer surface was observed. this fluorescence remained as long as the larvae were maintained at 2 degrees c. when these larvae were reincubated at 37 degrees c a gradual loss of fluorescence along their ou ... | 1981 | 7329441 |
| results of surgery for ocular toxocara canis. | it has been shown that the diagnosis of ocular toxocara canis is highly accurate when the typical clinical findings are associated with a positive elisa titer in the serum of 1:8 or greater. the inflammatory reaction in this disorder can be devastating and not infrequently leads to a tractional detachment of the posterior pole or a rhegmatogenous detachment and/or a progressive cyclitic membrane leading to phthisis bulbi. we have recently performed vitreoretinal surgery on 17 patients with compl ... | 1981 | 7335312 |
| ocular toxocariasis demonstrated by ultrasound. | a 10-year-old white girl had a painless loss of central vision in the right eye. a white mass partially surrounded by blood was present in the macula of the right eye. ultrasound examination revealed an elevated mass. elisa test for toxocara canis was positive. further history revealed contact with puppies. the elisa test ruled out tumor. | 1981 | 7337343 |
| retinal arterial obstruction in association with presumed toxocara canis neuroretinitis. | 1981 | 7337346 | |
| adult toxocara canis in the pancreas and peritoneal cavity of a pup. | 1981 | 7340792 | |
| studies on the incidence of toxocara and toxascaris spp. ova in the environment. 1. a comparison of flotation procedures for recovering toxocara spp. ova from soil. | seven different flotation fluids were assessed for their efficiency in recovering toxocara canis ova from artificially seeded soil samples. using the most efficient (a saturated solution of magnesium sulphate plus 5% potassium iodide) 25 g amounts of 234 environmental soil samples were examined for the presence of toxocara spp. and toxascaris ova. twenty-six samples (11.1%) yielded ova of one or other species. there was no discernible pattern of distribution of positives with relation to the sou ... | 1980 | 7351480 |
| human toxocariasis in a rural community. | a questionnaire and serologic survey of a pennsylvania community revealed that 23 (54%) of 43 study participants had antibody titers to toxocara canis (enzyme-linked immunosorbent assay test [elisa]) in the range defined as positive (greater than or equal to 1:32). age-specific seropositivity rates were highest among adults (greater than or equal to 18 years). positive titers ranged from 1:32 to 1:512. seropositivity did not cluster by family, and seropositivity rates were significantly higher t ... | 1980 | 7424857 |
| a survey of canine toxocariasis and toxocaral soil contamination in essex county, new jersey. | toxocara canis eggs were found in the feces of 33 of 246 dogs and in two of 629 soil samples from 32 public parks in essex county, new jersey. stool samples collected from these areas were free of t. canis eggs. the findings suggest that contamination of soil in public parks with t. canis eggs is not an important factor in the transmission of visceral larva migrans in this county. | 1980 | 7425196 |
| a paper radioimmunosorbent test (prist) for the detection of larva-specific antibodies to toxocara canis in human sera. | a paper radioimmunosorbent test (prist) was shown to be sensitive and reproducible when used with excretory/secretory antigen of toxocara canis second stage larvae. whatman no. 50 filter paper (5 mm discs) gave the most consistent and clear results with antigen at a concentration of 100 micrograms/ml, and could be stored for up to 3 weeks in vacuo at -70 degrees c. antigen coated discs were incubated with test sera at 1:10 dilution for 3 h at room temperature (21 degrees c), reacted with [125i]a ... | 1980 | 7430660 |
| [intestinal helminths in bangkok stray dogs and their role in public health (author's tranls)]. | feces examination of 107 stray dogs in bangkok, thailand, on intestinal helminths showed the following rates: hookworms 100%, trichuris vulpis 54.2%, toxocara canis 6.5%, gnathostoma spinigerum 2.8%, spirocerca lupi 17.8%, diphyllobothrium mansoni 1.9%, and opisthorchis viverrini 1.9%. out of these species hockworms (especially a. braziliense), t. canis, g. spinigerum, and d. mansoni are important sources of human cutaneous or visceral larva migrans, the latter two being special parasites of the ... | 1980 | 7435002 |
| recovery of large numbers of eosinophils from mice infected with toxocara canis. | as a method of recovering large numbers of eosinophils, mice were infected with toxocara canis which in 12 days produced a high peripheral eosinophilia; the mice were then injected intraperitoneally with an extract of t. canis adult or anisakis larval worms. two days after injection of extract, peritoneal exudates were withdrawn, washed, and enumerated; the exudates were observed to be 70--80% eosinophils with a mean total recovery of 1 x 10(8) eosinophils per mouse. | 1980 | 7435785 |
| veterinary and public health considerations in canine roundworm control: a survey of practicing veterinarians. | we conducted a survey to assess whether current veterinary practices concerning prophylaxis and treatment of canine roundworm (toxocara canis) infection are adequate to prevent the potential public health risks of visceral larva migrans. we administered a standard questionnaire by telephone to 100 small animal practitioners. fifty-four veterinarians included health education for the pet's owner as part of their routine care in a case of canine roundworm infection, and 39 recommended prophylactic ... | 1980 | 7440322 |
| [helminths of the common fox (vulpes vulpes l.) from the massif central (france) (author's transl)]. | sixty nine wild foxes originating from auvergne for the period january 1977 to january 1978 have shown intestinal parasites in the proportion of 76,8 per cent. 59,4 per cent are invaded with cestodes; 72,4 per cent with nematodes and none with trematodes. the list of the identified species is following: 1. cestodes. a) adults and fertile forms of: mesocestoides litteratus in 27,5 per cent of the hosts; taenia crassiceps in 15,9 p.c.; t. polyacantha in 27,5 p.c.; echinococcus multilocularis in 7, ... | 1980 | 7458165 |
| visceral larva migrans (toxocariasis) in toronto. | a 7-year-old child was admitted to toronto's hospital for sick children in 1976 with symptoms and laboratory findings compatible with visceral larva migrans, a disease usually caused by toxocara canis. this prompted a search for other cases seen at the hospital during the period 1952 through 1978. only 18 cases were discovered that met at least three of six criteria and thus were considered possible or probably cases of the disease. three possible cases of ocular toxocariasis during the same per ... | 1981 | 7459767 |
| immune responses to nematode exoantigens: sensitizing antibodies and basophil histamine release. | high levels of ige and eosinophilia are found in both allergy and helminth infections, but allergic symptoms are rare in naturally acquired helminth infections. the interrelation of specific ige antibodies and in vitro basophil histamine release (hr) induced by exoantigens from the larval stages (l2/l3) of the nematodes toxocara canis and ascaris suum was examined in 148 patients visiting an outpatient clinic for parasitic diseases. the antigen sensitivity of the basophils was found to be depend ... | 1994 | 7521141 |
| clinical and laboratorial features of visceral toxocariasis in infancy. | forty children with a diagnosis of visceral toxocariasis were evaluated prospectively from february 1982 to june 1989. diagnosis was established by clinical, laboratory and serological (elisa - es toxocara canis antigen) evaluations. a great clinical polymorphism was found in our patients, ranging from unspecific or absent manifestations to an exuberant symptomatology. the laboratory findings were: leukocytosis, eosinophilia and elevation of serum gammaglobulin and isohemagglutinin levels. no si ... | 1994 | 7527930 |
| idiotypic replica of a toxocara canis excretory/secretory antigen epitope. | this study describes the production, characterization and use of an anti-idiotype serum raised against the monoclonal antibody tc-1 which recognizes a t. canis excretory/secretory antigen (es ag) epitope. anti-idiotypic (anti-id or ab2) antibodies were produced in rabbits using tc-1 f(ab')2 fragments; these anti-id inhibited es ag binding to biotinylated tc-1, and also inhibited a larval microprecipitation assay using tc-1. assays show that the ab2 beta or "internal image" of a t. canis es ag ep ... | 1995 | 7541025 |
| a study on the prevention of prenatal and galactogenic toxocara canis infections in pups by treatment of infected bitches with ivermectin or doramectin. | investigations were carried out to test the efficacy of a two dose treatment with ivermectin or doramectin on reactivated larvae of toxocara canis in bitches to prevent prenatal and galactogenic infections of their pups. thirty pregnant bitches were treated by subcutaneous injection of ivermectin or doramectin on day 40 and 50 post conception (p.c.) each with a dose of 1 mg/kg body weight. the efficacy of the treatments was determined by faecal examinations and by comparing the number of infecte ... | 1995 | 7550440 |
| serological evidence for the presence of toxocariasis in the turkana district of kenya. | 1995 | 7570867 | |
| epidemiological studies on intestinal helminth parasites of rural and urban red foxes (vulpes vulpes) in the united kingdom. | an epidemiological study of intestinal helminths in 843 foxes (vulpes vulpes) from southern england revealed the presence of 13 parasite species: five nematodes--toxocara canis (prevalence 55.9%), toxascaris leonina (1.5%), uncinaria stenocephala (68.0%), trichuris vulpis (0.5%) and capillaria aerophila (0.2%); four cestodes--taenia pisiformis (13.8%), taenia hydatigena (2.5%), echinococcus granulosus (0.1%) and dipylidium caninum (3.8%); two trematodes--brachylaima recurva (2.9%) and cryptocoty ... | 1995 | 7571336 |
| a study on patients with eosinophilia of suspected parasitic origin. | a study of 53 patients with eosinophilia of suspected parasitic origin was conducted. investigations done for each case included, stool and urine examinations, absolute eosinophilic count and countercurrent immunoelectrophoresis (ciep) using crude antigens of fasciola hepatica, schistosoma mansoni worms, trichinella spiralis and toxocara canis larvae, and hydatid fluid. stool examination revealed six cases with fasciola eggs, two with ascaris lumbricoides and one with s. mansoni eggs. the eosino ... | 1995 | 7602166 |
| an abundant, trans-spliced mrna from toxocara canis infective larvae encodes a 26-kda protein with homology to phosphatidylethanolamine-binding proteins. | a full-length mrna encoding a secreted 26-kda antigen of infective larvae of the ascarid nematode parasite toxocara canis has been identified. this was characterized as a 1,082-base pair clone highly abundant (0.8-1.9%) in cdna prepared from infective stage larvae but absent from cdna from adult male worms. sequence analysis revealed an open reading frame corresponding to a hydrophilic 263-amino acid residue polypeptide with a 20-residue n-terminal signal peptide, indicating that it is secreted. ... | 1995 | 7629180 |
| optic neuritis in cerebral toxocariasis. | 1995 | 7629546 | |
| meiosis and some aspects of cytological mechanisms of chromosomal sex determination in nematode species. | meiotic division in toxascaris leonina, baylisascaris transfuga, hexametra sp., toxocara canis, t. cati, heterakis gallinarum and physaloptera clausa of the class nematoda were studied. chromosomal sex determination type in different taxa is described. the xx-xo type of sex determination predominates in the species examined. a y chromosome occurs only in b. transfuga. a correlation between the number and length of sex chromosomes and autosomes in the different taxa was established. | 1995 | 7635621 |
| evaluation by larval recovery of mebendazole activity in experimental murine toxocariasis. | we have studied the action of mebendazole on experimental murine toxocariasis using different formulations and vehicles. the treatment efficacy was evaluated by larval recovery after digesting several tissues. in the first part of the experiment, the drugs were administered on days 1-3 post infection (p.i.) inclusive (hepato-pulmonary phase of the migration), then the animals were sacrificed by the 1st week p.i. in the second part of the experimental protocol, the treatments were administered on ... | 1995 | 7635636 |
| the effects of freezing on the viability of toxocara canis and t. cati embryonated eggs. | suspensions of embryonated (l2) toxocara canis and t. cati eggs were maintained under freezing conditions in order to study the impact on their long term viability. the eggs had been removed from the uteri of adult toxocara spp. worms and the suspended in a 0.4% formalin solution before being frozen in 20 ml plastic tubes in the freezer compartment of a domestic refrigerator. assessment of embryonated egg viability over a period of 34 days was conducted by microscopic examination under a high li ... | 1995 | 7636161 |