Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [laboratory and clinical studies on cefteram pivoxil in the field of pediatrics]. | laboratory and clinical studies on cefteram pivoxil(cefteram) a new cephem antibiotic, were carried out in the field of pediatrics. the results obtained are summarized as follows: 1. serum concentrations, urinary concentrations and urinary recovery rates of cefteram (cftm) were determined upon oral administration after meal of cefteram pivoxil (cftm-pi) at doses of 3 mg/kg granules in 2 cases and 6 mg/kg granules in 2. peak serum levels of cftm were obtained at 3 hours in 2 cases and 4 hours in ... | 1989 | 2810748 |
| [clinical studies on cefteram pivoxil granules in pediatrics]. | a newly developed cephalosporin, cefteram pivoxil (cftm-pi, t-2588), was evaluated clinically in 40 patients. a pharmacokinetic study was also performed with 8 patients. cftm-pi was administered as granules. one patient was given cftm-pi at a dose of 1.5 mg/kg, each of 3 patients was given the drug at a dose of 3 mg/kg and each of 4 patients at a dose of 6 mg/kg. in most cases, serum concentrations of cftm were determined at 2, 3, 4, and 6 hours after dosing. urinary concentrations of cftm were ... | 1989 | 2810757 |
| characterisation of branhamella catarrhalis and differentiation from neisseria species in a diagnostic laboratory. | to distinguish branhamella catarrhalis from neisseria species a study of 140 strains was made on simple laboratory media, with particular reference to deoxyribonuclease (dnase) production, superoxol reaction, and growth characteristics. all 97 clinical isolates of b catarrhalis (58 of which were beta-lactamase positive) and eight strains of b catarrhalis from the national collection of type cultures were dnase positive and superoxol positive. none grew on modified new york city medium, modified ... | 1987 | 2826546 |
| a nosocomial outbreak of branhamella catarrhalis confirmed by restriction endonuclease analysis. | an outbreak of respiratory illness due to branhamella catarrhalis occurred in the intermediate care unit of a veterans administration hospital and involved patients and staff members. four patients had pneumonia and four had bronchitis. infected patients were placed in a cohort separated from noninfected patients and were treated. pharyngeal culture was used to survey prevalence in staff and all other patients on the unit; three of 18 staff members and two of 19 asymptomatic patients were positi ... | 1988 | 2834470 |
| the in-vitro activity of cp-62,993 against haemophilus influenzae, branhamella catarrhalis, staphylococci and streptococci. | the in-vitro activity of a new macrolide antibiotic cp-62,993 (pfizer ltd) was determined for 420 bacterial isolates, comprising 150 haemophilus influenzae, 48 branhamella catarrhalis, 50 staphylococcus aureus, 50 coagulase negative staphylococci, 50 beta-haemolytic streptococci, 50 streptococcus pneumoniae and 22 oral streptococci. cp-62,993 was compared with erythromycin and penicillin (ampicillin in the case of h. influenzae). the mics of cp-62,993 were found to be lower than those of erythro ... | 1988 | 2837451 |
| in vitro activities of azithromycin (cp 62,993), clarithromycin (a-56268; te-031), erythromycin, roxithromycin, and clindamycin. | the in vitro activity of azithromycin (cp 62,993 or xz-450) against haemophilus influenzae was greater than that of three other macrolides. however, azithromycin was four- to eightfold less active than erythromycin against the gram-positive cocci and against listeria monocytogenes. erythromycin and azithromycin were similar in their activity against legionella pneumophila, neisseria gonorrhoeae, neisseria meningitidis, and branhamella catarrhalis. | 1988 | 2840016 |
| rate of bactericidal activity for branhamella catarrhalis of a new macrolide, cp-62,993, compared with that of amoxicillin-clavulanic acid. | the rate of bactericidal activity of a new macrolide, cp-62,993, was compared with that of the combination of amoxicillin and clavulanic acid (in the proportion of 4 to 1) on strains of branhamella catarrhalis beta-lactamase producers. the antibacterial activity of cp-62,993 was bacterostatic at 0.01 micrograms/ml. after a 6-hour period of bacteriostasis a bactericidal activity (3 log10 cfu/ml) was observed for all concentrations from 0.1 to 10 micrograms/ml after 24 h. the bactericidal rate of ... | 1988 | 2843324 |
| beta-lactamase inhibition by acetylmethylene penicillanic acid compared to that of clavulanate and sulbactam. | the beta-lactamase inhibitory properties of 6-acetylmethylene penicillanic acid (6-ampa) were investigated and compared with those of other beta-lactamase inhibitors. 6-ampa inhibited the tem-1, tem-2, shv-1, pse-1, pse-2, pse-3, pse-4, oxa-2, oxa-3, and staphylococcus aureus beta-lactamases. it also inhibited the chromosomally-mediated beta-lactamases of the richmond-sykes type ia, ic and id type and the type iv klebsiella enzymes. beta-lactamases of branhamella catarrhalis and bacteroides frag ... | 1988 | 2850139 |
| branhamella catarrhalis prevalence in a hospital population. | the prevalence of environmental and nasopharyngeal carriage of branhamella catarrhalis in hospital staff members and in-patients was higher than previous studies suggested. pernasal swabs performed on 59 members of staff revealed four isolates of branh. catarrhalis, two of which were beta-lactamase producers. seven isolates, two beta-lactamase positive, were recovered from 89 in-patients none of whom had bronchopulmonary infection with branh. catarrhalis. from 117 settle plates six isolates, one ... | 1985 | 2859325 |
| branhamella catarrhalis cellulitis around a cerebrospinal fluid shunt: case report. | a cellulitis surrounding a cerebrospinal fluid shunt caused by branhamella catarrhalis is described. this is the first reported case of a cellulitis caused by this bacterium. | 1985 | 2865299 |
| branhamella catarrhalis associated with eye infection in the elderly. | 1985 | 2865306 | |
| a 2-year survey of branhamella catarrhalis in a general hospital. | during a 2-year period, 143 strains of branhamella catarrhalis were recovered from 7929 respiratory tract specimens (mainly sputa) sent for routine microbiological investigations at a 500 bed general hospital. the incidence of beta-lactamase positive strains increased from 2.7% in 1983 to 40% of isolates in the last 5 months of 1984; this increase continued in the early months of 1985. forty-four strains of bran. catarrhalis recovered from 35 patients were considered on laboratory generated data ... | 1986 | 2873174 |
| hospital-acquired bronchopulmonary infection in premature infants due to branhamella catarrhalis. | 1986 | 2873180 | |
| methicillin-resistant branhamella catarrhalis. | 1986 | 2873186 | |
| branhamella catarrhalis. new methods of bacterial diagnosis. | a total of 176 strains identified as branhamella catarrhalis were isolated from various clinical specimens, mainly sputum (71), pharynx (49), eye (24), nose (11), ear (6) and tracheal aspirate (7). b. catarrhalis appeared as gram-negative cocci in white colonies which were oxidase- and catalase-positive and which did not produce acidification of sugars. the 3 related species, neisseria caviae, n. ovis and n. cuniculi were also white but the 'true asaccharolytic neisseria' studied presented a yel ... | 1986 | 2874008 |
| branhamella catarrhalis chest infections. | 1986 | 2874292 | |
| production and characterization of monoclonal antibodies directed against bordetella pertussis lipopolysaccharide. | hybrid cell lines producing monoclonal antibodies against bordetella pertussis lipopolysaccharide (lps) were established. the specificity of the antibodies was ascertained by enzyme-linked immunosorbent assay (elisa) and elisa-inhibition experiments with lps and delipidated polysaccharide fragments (ps-1 and ps-2) prepared from b. pertussis lps. monoclonal antibody 9-1-h5 reacted with b. pertussis lps only, whereas monoclonal antibodies 6-4-h6 and 9-2-a8 reacted with ps-1 and ps-2 as well as b. ... | 1988 | 2893806 |
| restriction fragment mapping of branhamella catarrhalis: a new tool for studying the epidemiology of this middle ear pathogen. | 1988 | 2899124 | |
| monoclonal antibody-based sandwich enzyme-linked immunosorbent assay for detection of bordetella pertussis filamentous hemagglutinin. | hybrid cell lines producing monoclonal antibodies against bordetella pertussis filamentous hemagglutinin (fha) were established. the specificity of the antibodies was ascertained by enzyme-linked immunosorbent assay (elisa), sandwich elisa, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by electroblotting. the monoclonal antibody-based sandwich elisa was developed for detection of b. pertussis fha. the assay had a detection limit of b. pertussis fha in concentrations rang ... | 1988 | 2903174 |
| role of fluoroquinolones in lower respiratory tract infections. | oral quinolones such as ciprofloxacin are promising agents in the treatment of serious bronchopulmonary infections due to susceptible gram-negative micro-organisms such as haemophilus influenzae, branhamella catarrhalis, klebsiella pneumoniae and even pseudomonas aeruginosa. their moderative activity against streptococcus pneumoniae may limit the use of these agents in the treatment of acute exacerbations of chronic bronchitis and in the empiric management of community-acquired bacterial pneumon ... | 1989 | 2920482 |
| [new oral quinolone compounds in chronic bronchitis]. | clinical, microbiological and pharmacokinetic results are presented from studies in 186 patients treated with the new quinolone antimicrobial agents enoxacin, pefloxacin, ciprofloxacin or ofloxacin. almost all had been admitted to hospital for acute purulent exacerbations of chronic bronchitis, associated mainly with haemophilus influenzae, streptococcus pneumoniae, branhamella catarrhalis or pseudomonas aeruginosa. the h. influenzae and b. catarrhalis strains were generally very sensitive to th ... | 1986 | 2937739 |
| ciprofloxacin in the treatment of acute exacerbations of chronic bronchitis. | eighty hospital patients with acute purulent exacerbations of chronic bronchitis associated with haemophilus influenzae, streptococcus pneumoniae, branhamella catarrhalis or pseudomonas aeruginosa were treated with ciprofloxacin. the patients were divided into four groups of 20 patients each and administered either 500 mg, 750 mg (two different batches of tablets) or 1000 mg twice daily for ten days. most of the patients with haemophilus influenzae and branhamella catarrhalis infections were tre ... | 1986 | 2941287 |
| in vitro and in vivo antibacterial activity of am-833, a new quinolone derivative. | am-833 showed potent activity against members of the family enterobacteriaceae, neisseria spp., and haemophilus influenzae and good activity against staphylococci, pseudomonas aeruginosa, and branhamella catarrhalis. against these bacteria, its activity was roughly comparable to that of norfloxacin and ofloxacin but was slightly less potent than that of ciprofloxacin. this compound also showed good activity against drug-resistant strains such as methicillin-resistant staphylococcus aureus and ge ... | 1986 | 2942103 |
| [increasing role of branhamella catarrhalis in bronchopulmonary pathology in adults]. | 1987 | 2955369 | |
| in vitro antibacterial activity of trospectomycin (u-63366f), a novel spectinomycin analog. | trospectomycin (u-63366f) is a novel spectinomycin analog with broad-spectrum antibacterial activity. the in vitro activity of this analog was compared with that of spectinomycin and other reference antibiotics against 411 clinical isolates of aerobic and anaerobic bacteria. mics were determined by agar or broth dilution methods. the stability of trospectomycin in the presence of an enzyme extract derived from spectinomycin-resistant escherichia coli was determined. trospectomycin was more activ ... | 1988 | 2966608 |
| trospectomycin, a novel spectinomycin analogue: antibacterial activity and preliminary human pharmacokinetics. | trospectomycin (tsp; u-63366f) is a novel spectinomycin (sp) analogue with broad-spectrum antibacterial activity. the in vitro activity of the analogue was compared to that of sp against approximately 400 bacterial isolates. the in vivo activity of the compound was assessed using experimental infection models for both gram-positive and gram-negative facultative bacteria. the preliminary human pharmacokinetics of tsp were evaluated following single-dose i.v. or i.m. administration. tsp was more a ... | 1988 | 2975212 |
| clinical significance of respiratory infection caused by branhamella catarrhalis with special reference to beta-lactamase producing strains. | i found the recent increase during the past eight years of the incidence of respiratory infections caused by branhamella catarrhalis. namely, i experienced 74 cases (93 episodes) of the respiratory infections; 5 pneumonia, 14 acute bronchitis, 1 lung abscess, 36 chronic bronchitis, 7 chronic bronchiolitis, 21 bronchiectasis and 9 chronic pulmonary emphysema with infection. in 65 of 93 infectious episodes, branhamella catarrhalis was isolated as a pure culture and in 28 episodes it was associated ... | 1985 | 3000026 |
| sultamicillin (ampicillin-sulbactam) in the treatment of acute otitis media in children. | sultamicillin, a dimer of ampicillin and a beta-lactamase-inhibiting agent, sulbactam, was given in oral form to 50 infants and children with acute otitis media. tympanocentesis was performed on entry into the trial. beta-lactamase-positive haemophilus influenzae or branhamella catarrhalis was isolated from 14 of 73 (19.2%) middle ear effusions in 9 children. relief of symptoms (fever/otalgia) occurred in all children who completed therapy. however, in 8 children (16%), the antimicrobial agent w ... | 1986 | 3003716 |
| detection, distribution and inhibition of branhamella catarrhalis beta-lactamases. | beta-lactamase-producing isolates of branhamella catarrhalis were first detected in france in 1977. the frequency of beta-lactamase producers has increased, especially since 1980. an agar iodometric test, a fast chromogenic test and an acidimetric test were used to assess the beta-lactamase-producing capabilities of 188 isolates of b. catarrhalis obtained mainly from sputum and the pharynx. data from the first 2 procedures indicated positive beta-lactamase activity for all 49 strains of b. catar ... | 1986 | 3015547 |
| antibacterial activity of ofloxacin and its mode of action. | the antibacterial activity of ofloxacin against enterobacteriaceae, pseudomonas aeruginosa, haemophilus influenzae, branhamella catarrhalis, and neisseria gonorrhoeae was comparable to norfloxacin and enoxacin, and far exceeded the activity of pipemidic acid and nalidixic acid. the activity of ofloxacin was two to eight times less than that of ciprofloxacin. ofloxacin was more active against staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, acinetobacter spp., legionel ... | 1986 | 3028966 |
| [laboratory and clinical studies on cefotetan in respiratory tract infections]. | seventy five patients with respiratory infections, including 40 cases of acute pneumonia, 33 cases of secondary infection after chronic pulmonary diseases and 2 cases of pulmonary abscess, were treated with cefotetan (ctt, yamatetan) by drip infusion in order to evaluate its clinical efficacy. the overall rate of effectiveness was 83.8%. ctt was examined comparatively with other beta-lactam antibiotics for antibacterial activity on clinically isolated strains of 3 major respiratory pathogens inc ... | 1988 | 3043035 |
| [studies on susceptibility of isolated organisms from pediatric infections against various antimicrobial agents]. | twelve oral antimicrobial agents were tested for their antimicrobial activities against causative organisms isolated from pediatric infections. activities of these antimicrobial agents against streptococcus pyogenes were also examined in relation to t-antigen typing of the species. the results of the investigation are summarized as follows. 1. against staphylococcus aureus, rokitamycin (rkm), josamycin, ofloxacin, minocycline exhibited strong antimicrobial activities, and few strains of s. aureu ... | 1988 | 3050184 |
| comparative in-vitro activity of a new oral carbacephem, ly163892. | the in-vitro activity of a new oral carbacephem, ly163892, was compared with cefaclor, cephalexin, cephradine, cefadroxil and selected penicillins against 529 bacterial isolates. ly163892 exhibited greater activity in vitro than all four cephalosporins against haemophilus influenzae, beta-lactamase producing branhamella catarrhalis, escherichia coli, klebsiella spp. and proteus mirabilis. ly163892 had equivalent potency to cefaclor against non-beta-lactamase producing b. catarrhalis, streptococc ... | 1988 | 3060458 |
| cefuroxime axetil. | cefuroxime axetil is a orally active prodrug formulation of cefuroxime, which upon absorption undergoes immediate deesterification to free cefuroxime. cefuroxime axetil offers an in vitro antibacterial spectrum against many gram-positive and some gram-negative organisms. its beta-lactamase stability makes it useful in treating a variety of infections caused by beta-lactamase-producing strains of haemophilus influenzae, branhamella catarrhalis, and staphylococcus aureus. cefuroxime axetil has goo ... | 1988 | 3063476 |
| [clinical trials of flomoxef in patients with chronic respiratory tract infections]. | flomoxef (fmox, 6315-s), a newly developed oxacephem drug, was administered to 6 patients with chronic respiratory tract infections. bacteriological examination of these infections using quantitative sputum cultures revealed that 2 patients had haemophilus influenzae, 2 had branhamella catarrhalis and 2 had mixed pathogens (one was with h. influenzae + b. catarrhalis and the other with streptococcus pneumoniae + b. catarrhalis). the administration of the drug was done by drip infusion, twice dai ... | 1988 | 3063850 |
| management of otitis media in infants and children: current role of old and new antimicrobial agents. | otitis media, the diagnosis most frequently made by the pediatrician, is most effectively treated with antimicrobial therapy. amoxicillin (or ampicillin) has been the standard for infants and children with acute otitis media because it is safe and effective for most of the causative bacterial pathogens. amoxicillin has also been shown to be effective for treatment of some children with otitis media with effusion ("secretory" otitis media) and is the recommended prophylactic antimicrobial agent f ... | 1988 | 3064037 |
| sinusitis in children. | upper respiratory tract infection and allergic inflammation are recognized as the important risk factors for acute sinusitis, with upper respiratory tract infection being most common. in children with acute or chronic sinusitis, the respiratory symptoms of nasal discharge, nasal congestion and cough are usually prominent. radiography has traditionally been used to determine the presence or absence of sinus disease. the radiographic findings most diagnostic of bacterial sinusitis are diffuse opac ... | 1988 | 3064040 |
| increase in bronchopulmonary infection due to branhamella catarrhalis. | in a six month prospective study during the winter branhamella catarrhalis was isolated from the sputum of 63 patients with symptoms of bronchopulmonary infection: 49 isolates were in pure culture and 14 were with another pathogen, haemophilus influenzae being the commonest (found with 10 of the 14 b catarrhalis isolates). of 36 patients infected in the community, 26 required admission to hospital. the remaining 27 patients were infected while in hospital. forty four of the 63 isolates produced ... | 1986 | 3084017 |
| increase in bronchopulmonary infection due to branhamella catarrhalis. | 1986 | 3087474 | |
| preliminary evaluation of a rapid colorimetric method for identification of pathogenic neisseria. | a rapid colorimetric method for the identification of pathogenic neisseria (identicult-neisseria; scott laboratories, inc.) based on beta-galactosidase, gamma-glutamylaminopeptidase, and gamma-prolylaminopeptidase is described. all 82 clinical isolates of neisseria gonorrhoeae, 9 clinical isolates of n. meningitidis, and 5 clinical isolates of n. lactamica were correctly determined to the species level, as were 4 isolates of branhamella catarrhalis. reactions were prompt and easily interpreted. ... | 1986 | 3088030 |
| emergence of beta-lactamase producing anaerobic bacteria in the tonsils during penicillin treatment. | the emergence of beta-lactamase producing bacteria in the microflora in the oropharyngeal cavity was studied in ten healthy volunteers treated with 1 g phenoxymethylpenicillin b.i.d. for ten days. beta-lactamase activity in saliva was also investigated. a significant increase in the number of beta-lactamase producing strains of bacteroides species and fusobacterium nucleatum was observed. one beta-lactamase producing staphylococcus aureus strain was recovered in one of the volunteers before the ... | 1986 | 3093222 |
| [aerobic bacterial flora of the nasal cavity of rabbits]. | on the basis of bacteriological examinations carried out in april 1984 on 60 intranasal swabs, aerobic respiratory microbes were studied in rabbits. differences in flora between animals with and without respiratory diseases were studied. fourteen bacterial species were identified with no difference due to the pathological status. they were: bordetella bronchiseptica, staphylococcus epidermidis, streptococcus faecalis, pasteurella multocida, staphylococcus aureus, bacillus sp., branhamella catarr ... | 1986 | 3096189 |
| antimicrobial activity of cefmetazole (cs-1170) and recommendations for susceptibility testing by disk diffusion, dilution, and anaerobic methods. | cefmetazole, formerly cs-1170, was found to have antimicrobial activity slightly superior to that of cefoxitin but a clinically usable antimicrobial spectrum that should be considered identical to that of cefoxitin. disk diffusion and dilution test methods with cefmetazole correlated highly (r, greater than or equal to 0.95) with cefoxitin results. the recommended 30-micrograms cefmetazole disk interpretive breakpoints for susceptibility and resistance were greater than or equal to 18 mm (mic, l ... | 1986 | 3097064 |
| antimicrobial activity of ly164846, a new oral cephalosporin, and recommendations for disk diffusion tests. | ly164846 is a new oral cephalosporin with a limited spectrum of antimicrobial activity that includes staphylococci (other than methicillin-resistant), streptococci (other than enterococci), haemophilus influenzae (beta-lactamase-negative and beta-lactamase-positive), branhamella catarrhalis (beta-lactamase-negative and beta-lactamase-positive), and neisseria species (beta-lactamase negative and beta-lactamase-positive). the tentative recommendations for susceptibility breakpoints are less than o ... | 1987 | 3100126 |
| api quadferm+ with rapid dnase for identification of neisseria spp. and branhamella catarrhalis. | the quadferm+ system (analytab products, plainview, n.y.), a 2-h carbohydrate degradation method for the identification of neisseria spp., was evaluated along with a rapid dnase test for confirmation of branhamella catarrhalis. quadferm+ identified 100% of 82 n. gonorrhoeae and 96% of 54 n. meningitidis strains. the two misidentified meningococcal strains were biochemically atypical and were also misidentified by the conventional method. of 26 n. lactamica strains, 25 (96%) were correctly identi ... | 1987 | 3102550 |
| bmy 28100, a new oral cephalosporin. | bmy 28100, a new oral cephalosporin with a (z)-propenyl side chain at the 3 position and a p-hydroxyphenylglycyl substituent at the 7 position, was evaluated in comparison with cefaclor and cephalexin and, when appropriate, ampicillin and vancomycin. in vitro, bmy 28100 was more active than the reference cephalosporins against streptococci, staphylococcus aureus, staphylococcus epidermidis, listeria monocytogenes, haemophilus influenzae, propionibacterium acnes, clostridium perfringens, and clos ... | 1987 | 3105449 |
| in vitro activity of ro 23-6240 (am-833): a new fluoroquinolone. | the in vitro activities of ro 23-6240 (am-833) and four comparative fluoroquinolones were studied. minimal inhibitory concentrations (mics) of ro 23-6240, which inhibited at least 90% of strains, were less than or equal to 0.03-1 microgram/ml for staphylococcus aureus, staphylococcus epidermidis, enterobacteriaceae, acinetobacter anitratus aeromonas hydrophila, branhamella catarrhalis, and haemophilus influenzae, 2-8 micrograms/ml for staphylococcus saprophyticus, streptococci, diphtheroids, and ... | 1987 | 3107872 |
| etiology and diagnosis of neonatal conjunctivitis. | chlamydia trachomatis was isolated from the most inflamed eye of 13 of 107 (12%) infants with neonatal purulent conjunctivitis and from none of 100 healthy infants (p less than 0.01). staphylococcus aureus was recovered from 49 (46%) inflamed eyes and from 8 (8%) healthy eyes (p less than 0.01). streptococcus pneumoniae, haemophilus influenzae, branhamella catarrhalis, escherichia coli and klebsiella pneumoniae were isolated from very few infants with conjunctivitis but not from controls. no org ... | 1987 | 3109205 |
| supplement peptone agar--a simple carbohydrate degradation plate medium for the identification of neisseria species. | a carbohydrate degradation medium was developed for the detection of acid production by neisseria species and branhamella catarrhalis. a total of 223 clinical isolates were identified by supplemented peptone agar and the results were compared with those of cystine trypticase agar. supplemented peptone agar and cystine trypticase agar correctly identified 99.1% and 93.7% of the total strains respectively within 24 h. with cystine trypticase agar method another 4% of the isolates could be identifi ... | 1987 | 3115001 |
| the influence of culture medium on the comparative in-vitro activity of amoxycillin and amoxycillin/clavulanic acid against branhamella catarrhalis. | 1987 | 3117763 | |
| optimal dilution susceptibility testing conditions, recommendations for mic interpretation, and quality control guidelines for the ampicillin-sulbactam combination. | the ampicillin-sulbactam combination was evaluated in vitro to determine the optimal susceptibility testing conditions among five combination ratios and four fixed concentrations of sulbactam. the organisms tested were markedly resistant to aminopenicillins and most other beta-lactams. the ratio of 2:1 is recommended to assure recognition of the ampicillin-sulbactam spectrum and minimize false-susceptible results among strains known to be resistant to this combination. proposed mic breakpoint co ... | 1987 | 3117843 |
| respiratory tract infections due to branhamella catarrhalis: epidemiological data from western australia. | during a 3-year period branhamella catarrhalis was isolated in significant numbers from 239 (1.3%) of 19,488 specimens of sputum sent for routine microbiological examination at a 700-bed general hospital. the majority of patients (83%) were over 60 years of age and 65% were male. there was a distinct seasonal variation in isolations with a peak incidence during the winter and early spring, a pattern not found with other pathogens. susceptibility to amoxycillin decreased by approximately 50% over ... | 1987 | 3119360 |
| correlation between branhamella catarrhalis adherence to oropharyngeal cells and seasonal incidence of lower respiratory tract infections. | bacterial colonization of the oropharynx is the initial event in most lower respiratory tract infections. to study the role of bacterial adherence in lower respiratory tract infections caused by branhamella catarrhalis (b. catarrhalis) in winter, in vitro adherence assays of the organism to human oropharyngeal cells were carried out in winter, spring, summer and autumn. a total of 57 adults of both sexes were studied from january to december 1985. forty eight persons of 57 had chronic pulmonary ... | 1987 | 3120353 |
| recovery of beta-lactamase producing bacteria in pediatric infections. | the presence of beta-lactamase producing bacteria (beta lpb) was investigated in specimens obtained from 1469 children who presented with infections of the skin and soft tissue (648), upper respiratory tract (514), pulmonary sites (137), surgical sites (113), and other (57). of 4989 bacterial isolates recovered, 910 (18%) were beta lpb, 492 (54%) aerobes, and 418 (46%) anaerobes. the beta lpb were recovered in 751 (51%) of the children. the most frequently recovered beta lpb was staphylococcus a ... | 1987 | 3121158 |
| ro 23-6240 (am-833), a new fluoroquinolone: in vitro antimicrobial activity and tentative disk diffusion interpretive criteria. | the susceptibility of over 7000 recent clinical bacterial isolates to ro 23-6240, a new trifluorinated quinolone, was determined at four medical centers. over 99% of enterobacteriaceae and 97% of staphylococci were inhibited by less than or equal to 2.0 micrograms/ml of ro 23-6240. only 71% of pseudomonas spp. were inhibited by this concentration. streptococci and enterococci were resistant to ro 23-6240. clinical isolates of haemophilus spp., pathogenic neisseria spp., and branhamella catarrhal ... | 1987 | 3121241 |
| rapid identification of pathogenic neisseria species and branhamella catarrhalis. | two systems, the identicult-neisseria (idn; scott laboratories, inc., fiskeville, r.i.) strip and the neisseria/haemophilus identification test kit (nhi; vitek systems, inc., hazelwood, mo.) card, were compared with the 4-h minitek system (bbl microbiology systems, cockeysville, md.) for their ability to rapidly identify 157 pathogenic neisseria and branhamella catarrhalis isolates. idn, limited in its identification to four species, when incubated at 35 degrees c for 10 min identified 99% of th ... | 1987 | 3121668 |
| [susceptibility of bacteria isolated from the patients with lower respiratory tract infections to antibiotics (1985)]. | it has been more than 4 years since third-generation cephems were introduced into clinical practice. the range of our drug selection definitely tends to increase, because we today have more antibiotics with wider spectrum, antibiotics with strong activities only against gram-negative strains, such as monobactams, and those with tremendously high activities such as quinolone carboxylic acid derivatives, in comparison to those we had in the past. among isolates obtained mainly from sputa of 567 pa ... | 1987 | 3121887 |
| branhamella catarrhalis as a cause of bacterial tracheitis. | 1987 | 3122157 | |
| branhamella catarrhalis and streptococcus pneumoniae type 9 causing recurrent coalescent mastoiditis. | 1987 | 3122159 | |
| branhamella catarrhalis respiratory infections. | branhamella catarrhalis, a normal commensal of the oropharynx, is increasingly recognized as an important cause of bronchitis and bacterial pneumonia. six patients with b. catarrhalis pneumonia documented by transtracheal aspirate or blood culture were studied, and 429 previously reported cases of b. catarrhalis bronchitis and pneumonia were reviewed. the mean age of patients with b. catarrhalis infection was 64.8 years, and preexisting chronic obstructive pulmonary disease was common. the typic ... | 1987 | 3122301 |
| branhamella catarrhalis: beta-lactamase production and sensitivity to oral antibiotics, including new cephalosporins. | 1987 | 3123451 | |
| disk diffusion susceptibility testing of branhamella catarrhalis with ampicillin and seven other antimicrobial agents. | a total of 74 clinical isolates of branhamella catarrhalis were characterized with respect to their ampicillin, amoxicillin-clavulanate, cephalothin, cefaclor, erythromycin, tetracycline, chloramphenicol, and trimethoprim-sulfamethoxazole mics and zones of inhibition. disk diffusion tests were performed according to the guidelines of the national committee for clinical laboratory standards with two different media (mueller-hinton agar and chocolate mueller-hinton agar) and plates incubated under ... | 1987 | 3124732 |
| panel of reference strains for evaluating serologic reagents used to identify gonococci. | a panel of strains for evaluating neisseria gonorrhoeae serologic reagents was developed. the strains selected for the panel were antigenically diverse and representative of strains isolated worldwide and had been isolated from a variety of anatomic sites. a few strains with characteristics that can cause problems in serologic tests were included. the panel of 52 gonococcal and 20 nongonococcal strains was used to evaluate two commercially produced kits with monoclonal antibody reagents, gonogen ... | 1988 | 3125222 |
| branhamella catarrhalis as a possible skin pathogen. | 1987 | 3128412 | |
| selective medium with dnase test agar and a modified toluidine blue o technique for primary isolation of branhamella catarrhalis in sputum. | a selective medium with dnase test agar and incorporating vancomycin (10 micrograms/ml), trimethoprim (8 micrograms/ml), and amphotericin b (2 micrograms/ml) supported the growth of 305 branhamella catarrhalis isolates. a modified toluidine blue o technique was used after 48 h of incubation in co2 to overlay suspected b. catarrhalis colonies. a metachromatic color change was observed in 15 min, indicating dnase production. in 200 unselected sputum samples of hospitalized patients, this method wa ... | 1988 | 3128575 |
| evaluation of eight methods for identification of pathogenic neisseria species: neisseria-kwik, rim-n, gonobio-test, minitek, gonochek ii, gonogen, phadebact monoclonal gc omni test, and syva microtrak test. | the performance of eight methods in identifying neisseria species, particularly n. gonorrhoeae, was evaluated. these methods included four rapid carbohydrate utilization tests (gonobio-test, neisseria-kwik, rim-n, and minitek); the gonochek ii, a test which is based on the utilization of chromogenic substrates; and three monoclonal antibody tests (syva microtrak, gonogen, and phadebact monoclonal gc omni test). in all, 182 isolates comprised in six species of neisseria as well as branhamella cat ... | 1988 | 3128578 |
| antimicrobial resistance in branhamella catarrhalis. | 1988 | 3129387 | |
| enoxacin in acute exacerbations of chronic bronchitis: a comparison with amoxycillin. | a total of 43 hospitalized adult patients with acute exacerbations of chronic bronchitis or bronchiectasis due to gram-negative bacteria were randomized to receive either enoxacin (400 mg bd) or amoxycillin (1,000 mg tid) for 7-12 days. micro-organisms isolated included 24 haemophilus influenzae (three beta-lactamases positive), 11 branhamella catarrhalis (six beta-lactamase positive), two pseudomonas aeruginosa and two neisseria meningitidis in 37 evaluable patients. in the enoxacin group (23 p ... | 1988 | 3129390 |
| immunoglobulin g (igg) serological response to branhamella catarrhalis in patients with acute bronchopulmonary infections. | over 12 months serum was collected from 45 inpatients, with acute bronchopulmonary infection, in whose sputum branhamella catarrhalis predominated, or was the sole pathogen. serum was examined for igg against b catarrhalis using an immunofluorescence antibody test. acute and convalescent sera were compared with sera of age and sex matched controls. the convalescent sera had significantly higher titres than the acute sera which in turn had higher titres than the controls. the findings confirm the ... | 1988 | 3129454 |
| newer oral antimicrobials and newer etiologic agents of acute bronchitis and acute exacerbations of chronic bronchitis. | although the role of antimicrobial therapy in the treatment of chronic bronchitis is unproven, physicians continue to look for microbial etiologies to explain episodes of clinical acute bronchitis and better antimicrobial agents with which to treat these episodes. the newest major pathogen of acute bronchitis is branhamella catarrhalis, a neisseriae-like organism that has become the third most commonly recognized cause of this disease after haemophilus influenzae and streptococcus pneumoniae. be ... | 1988 | 3129770 |
| in vitro activities of 39 antimicrobial agents for branhamella catarrhalis and comparison of results with different quantitative susceptibility test methods. | the in vitro activities of 39 antimicrobial agents were assessed versus 74 clinical isolates of branhamella catarrhalis. resistance was observed only with penicillin and ampicillin and then only with beta-lactamase-producing strains. the results of in vitro susceptibility tests with agar dilution and broth microdilution procedures were found to be comparable. the results of broth tube macrodilution tests were, in general, one twofold-concentration increment higher. | 1988 | 3129988 |
| in vitro susceptibilities of common pediatric pathogens to ly163892. | ly163892 is a carbacephem antibiotic for oral administration with an antibacterial spectrum similar to that of cefaclor and amoxicillin-clavulanic acid. it has greater stability than cefaclor and greater activity against beta-lactamase-producing haemophilus influenzae and escherichia coli. ly163892 is less active than amoxicillin against streptococci and less active than amoxicillin-clavulanic acid against branhamella catarrhalis but comparable against other pathogens. | 1988 | 3129989 |
| emergence and persistence of beta-lactamase-producing bacteria in the oropharynx following penicillin treatment. | the emergence and persistence of aerobic and anaerobic beta-lactamase-producing bacteria (blpb) were investigated in 26 children treated with penicillin for otitis media or pharyngitis and in 28 nontreated control children. beta-lactamase-producers were isolated in three (12%) of the treated children before therapy, in 12 (46%) seven to ten days after completion of therapy, in nine (35%) 40 to 45 days after therapy, and in seven (27%) 85 to 90 days after therapy. these organisms were present in ... | 1988 | 3130087 |
| sputum microbiology in a district general hospital. the role of branhamella catarrhalis. | evidence is presented that supports the view that branhamella catarrhalis has a pathogenic role in chronic chest disease, similar in many respects to haemophilus influenzae. it was isolated from 4% of sputum specimens (compared to 10% for haemophilus influenzae). fifty-three per cent produced beta-lactamase, and all were resistant to trimethoprim. the relevance of these findings to antibiotic treatment is discussed. | 1987 | 3130089 |
| branhamella catarrhalis septicemia in patients with leukemia. | during a 10-year period, four patients with leukemia were identified who had branhamella catarrhalis septicemia. two patients had acute leukemia and the remaining two had chronic myelogenous leukemia with blastic transformation. all patients were febrile and neutropenic at the onset of the septicemia. after appropriate antibiotic therapy, they recovered from their infection despite persistence of neutropenia. because beta-lactamase-producing bacteria are an increasing cause of nosocomial infecti ... | 1988 | 3130177 |
| evaluation of a rapid method for identifying branhamella catarrhalis. | the speed and precision of hydrolysis of tributyrin to butyric acid as a test to detect branhamella catarrhalis were evaluated. the test proved consistently reliable in the identification of strains and correctly differentiated b catarrhalis from neisseria sp. the combination of gram stain, oxidase, and catalase tests to tributyrin hydrolysis provides a means of positive same day identification of b catarrhalis. | 1988 | 3130412 |
| [acute laryngobronchitis by moraxella subgenus branhamella catarrhalis (infantile case report)]. | 1987 | 3130436 | |
| comparison of the microbiology of group a and non-group a streptococcal tonsillitis. | we studied the microbial flora of tonsils removed from 20 children who suffered from recurrent group a beta-hemolytic streptococcal (gabhs) tonsillitis and 20 who had tonsillar hypertrophy following recurrent non-gabhs tonsillitis. similar polymicrobial aerobic and anaerobic flora were recovered from the cores of the tonsils in each group. beta-lactamase-producing bacteria (blpb) were recovered more often in the group with gabhs. this difference was due mostly to the lower incidence of beta-lact ... | 1988 | 3132074 |
| host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from neisseria gonorrhoeae and related species. | high-level tetracycline resistance in strains of neisseria gonorrhoeae, neisseria meningitidis, kingella denitrificans, and eikenella corrodens has recently been described. the resistance in each species is due to the acquisition of 25.2-megadalton conjugative plasmids that carry the tetracycline resistance determinant tetm. we examined the ability of commensal neisseria species to serve as recipients in conjugation for these new plasmids. most of the recipients (n = 21) tested had detectable co ... | 1988 | 3132092 |
| evaluation of a ten-minute chromogenic substrate test for identification of pathogenic neisseria species and branhamella catarrhalis. | a ten-minute chromogenic substrate test was evaluated for its ability to rapidly identify pathogenic neisseria spp. and branhamella catarrhalis. identifications obtained with this system were compared to those obtained using conventional procedures. the test correctly identified 98.9% of 90 neisseria gonorrhoeae, 98.3% of 60 neisseria meningitidis, 96.2% of 26 neisseria lactamica, and 100% of 36 branhamella catarrhalis strains. eight neisseria subflava strains that grew on modified thayer-martin ... | 1988 | 3132371 |
| comparative antimicrobial activity of the new macrolide flurithromycin against respiratory pathogens. | the activity of flurithromycin against haemophilus influenzae, streptococcus pneumoniae, streptococcus pyogenes, branhamella catarrhalis and staphylococcus aureus was determined by the agar dilution method. flurithromycin showed high activity against streptococcus pneumoniae, streptococcus pyogenes and branhamella catarrhalis (mic90 = 0.032-0.25 mg/l). its mic90 value against haemophilus influenzae strains was 4.0 mg/l and 16 mg/l against staphylococcus aureus strains. flurithromycin has promisi ... | 1988 | 3132384 |
| the effects of sinus bacteria on human ciliated nasal epithelium in vitro. | the mechanisms by which bacteria colonize and damage ciliated epithelium are important in understanding the pathophysiology of rhinitis, sinusitis, and otitis. bacteria that have the ability to impair mucociliary clearance would be at an advantage in establishing infection of ciliated surfaces. this study investigates the effect of hemophilus influenzae, streptococcus pneumoniae, branhamella catarrhalis, and staphylococcus epidermidis on the ciliary activity of normal ciliated nasal epithelium i ... | 1988 | 3132682 |
| [branhamella catarrhalis infection]. | 1988 | 3133094 | |
| rapid identification of branhamella catarrhalis with 4-methylumbelliferyl butyrate. | branhamella catarrhalis can be distinguished from neisseria spp. by the presence of butyrate esterase. this enzyme can be rapidly detected when 4-methylumbelliferyl butyrate is used as the substrate. all b. catarrhalis strains tested gave a positive fluorescence reaction within 5 min, while neisseria spp. remained negative, even after 18 h of incubation. | 1988 | 3133392 |
| profiles of amino-acid utilisation and production amongst strains of branhamella catarrhalis. | utilisation and production of amino acids by isolates of branhamella catarrhalis was studied by ion exchange chromatography after cells had been grown in nutrient broth and mueller-hinton broth. the profiles of amino acids used and produced by each strain were compared by a single linkage cluster algorithm. the results of this study reflect the biochemical and physiological heterogeneity amongst strains of b. catarrhalis. | 1988 | 3133481 |
| [branhamella catarrhalis: incidence in pulmonary infections and determination of sensitivity to 5 antibiotics]. | this study reports 45 cases of respiratory tract infection associated with branhamella catarrhalis, diagnosed by bacteriological examination out of 980 sputum samples studied over a 6 months period. these infections were observed mainly in patients with chronic respiratory disease (68.9%). more than half of the isolates were found in pure culture, others were isolated from mixed infections most often with haemophilus influenzae, streptococcus pneumoniae or h. influenzae plus s. pneumoniae. 64.7% ... | 1988 | 3136431 |
| bactericidal activity of bmy-28100 versus amoxicillin/clavulanic acid against branhamella catarrhalis. | 1988 | 3137055 | |
| [respiratory infections caused by branhamella catarrhalis: clinical analysis concerning its pathogenicity]. | 1988 | 3137299 | |
| adherence of branhamella catarrhalis to human pharyngeal cells: its role in the pathogenesis of lower respiratory infection. | 1988 | 3138342 | |
| the epidemiology of respiratory tract pathogens in southern netherlands. | results of sputum cultures and susceptibility tests have been reviewed for the years 1977-1986, with approximately 1,700 positive cultures per year. haemophilus influenzae always occupied the first place, being grown in 65% of positive specimens in 1977 and 37% in 1986. streptococcus pneumoniae occupied the second place, rising from 17 to 27% in the same period, during which branhamella catarrhalis rose from 5 to 26%. based on the frequency of occurrence of individual bacterial species in the sp ... | 1988 | 3139445 |
| laboratory diagnosis of branhamella catarrhalis. | 1988 | 3139719 | |
| comparison of the outer membrane proteins of 50 strains of branhamella catarrhalis. | branhamella catarrhalis colonizes the respiratory tract of humans and commonly causes otitis media in children and respiratory infections in adults with chronic lung disease. in view of the emergence of this organism as an important human pathogen, we used sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) to examine the outer membrane proteins (omps) of 50 strains of b. catarrhalis. omps were isolated from broth culture supernatants. typical of other gram-negative bacteria, ei ... | 1988 | 3139777 |
| branhamella catarrhalis sepsis: a case report and review of the literature. | 1988 | 3139780 | |
| recurrent and penicillin v-resistant otitis media. a treatment study with amoxycillin/clavulanate and cefaclor. | clinical and bacteriological studies were performed in 122 children, aged 1-10 years, with recurrent otitis media or failed therapy with phenoxymethyl penicillin. a specimen for bacteriological culture was taken from the nasopharynx in all patients, and in our material haemophilus influenzae, branhamella catarrhalis and streptococcus pneumoniae were equally distributed, each forming one-third of the total bacterial count. thus, h. influenzae and b. catarrhalis (as well as their betalactamase-pro ... | 1988 | 3140574 |
| branhamella catarrhalis meningitis following otolaryngologic surgery. | a case of pyogenic meningitis caused by branhamella catarrhalis which occurred after pharyngoplasty, adenoidectomy and tympanostomy tube placement is reported. this organism is morphologically similar to neisseria meningitidis but often produces beta lactamase. therefore therapy should be directed by proper microbiologic identification and sensitivity results. | 1988 | 3140851 |
| efficacy of penicillin treatment in purulent maxillary sinusitis. a european multicenter trial. | three hundred and one patients with maxillary sinusitis participated in a double-blind, randomized study at 11 ent-clinics in europe. sinusitis was diagnosed by the presence of at least two signs and symptoms and sinus x-ray showing more than 6 mm swelling of the maxillary mucosa. a microbiological specimen was obtained by intrasinusal aspiration. the patients were randomly assigned to treatment either with bacampillin 800 mg b. i. d. or with amoxicillin 500 mg t. i. d. for ten days. the most fr ... | 1988 | 3141290 |
| spiramycin: in-vitro activity on branhamella catarrhalis. | this in-vitro study of susceptibility to spiramycin of 103 strains of branhamella catarrhalis isolated between 1982 and 1987 was performed by evaluation of their mics. more than 97% of strains remained susceptible with mic less than or equal to 8 mg/l (two strains). one strain presented a mic of 16 mg/l. there were no significant differences of susceptibility to spiramycin between penicillinase-producing and non-producing strains. | 1988 | 3141349 |
| [in vitro activity of 3 fluoroquinolones on branhamella catarrhalis]. | the in vitro antibacterial activities of three fluoroquinolones (pefloxacin, ofloxacin, ciprofloxacin) against 90 clinical isolates of branhamella catarrhalis were assessed by determination of minimum inhibitory concentrations (mics). 73.5% of the strains were producing penicillinase. the mics90 were as follow: ciprofloxacin = 0.2 mg/l. the mic50 and the mic90 were similar. there was no correlation of mics with beta-lactam resistance. lung parenchyma and bronchial mucus diffusion of these three ... | 1988 | 3141885 |
| branhamella catarrhalis bacteremia in children. | 1988 | 3141896 | |
| plasma bactericidal activity after administration of erythromycin estolate and erythromycin ethylsuccinate to healthy volunteers. | in a crossover design study, we compared the plasma bactericidal activities of erythromycin estolate (500 mg) and erythromycin ethylsuccinate (600 mg) after administration of a single oral dose to 12 healthy volunteers. both erythromycin esters displayed very good plasma bactericidal activities against streptococcus pneumoniae. the median bactericidal titers produced in plasma against streptococcus pyogenes and streptococcus pneumoniae were significantly higher with erythromycin estolate than wi ... | 1988 | 3142349 |