Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria. | The antimicrobial activity of four labdane-type diterpenes isolated from the oleoresin of Copaifera langsdorffii as well as of two commercially available diterpenes (sclareol and manool) was investigated against a representative panel of microorganisms responsible for periodontitis. Among all the evaluated compounds, (-)-copalic acid (CA) was the most active, displaying a very promising MIC value (3.1 µg mL-1; 10.2 µM) against the key pathogen (Porphyromonas gingivalis) involved in this infectio ... | 2011 | 22101836 |
| Associations of periodontal microorganisms with salivary proteins and MMP-8 in gingival crevicular fluid. | OBJECTIVE: We investigated in subjects with and without periodontitis, the levels of certain salivary proteins and matrix metalloproteinase-8 (MMP-8) in gingival crevicular fluid (GCF), in relation to the presence of specific periodontal pathogens. METHODS: Clinical parameters were recorded at baseline, in 1985 and in 2009 from 99 subjects; 56 with and 43 without periodontitis (mean age 59.2 ± SD 2.9). Saliva samples collected in 2009 were analysed for salivary albumin, total protein and immunog ... | 2011 | 22103335 |
| Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling. A randomized, split-mouth controlled clinical trial. | The objective of this work was to compare the effects of antimicrobial photodynamic therapy (PDT), diode soft laser therapy (DSL), and thorough deep scaling and root planing (SRP) for treatment of residual pockets. Thirty-two subjects with a history of non-surgical treatment for chronic periodontitis were included. Residual pockets >4 mm and bleeding upon probing were debrided with an ultrasonic device and then subjected to either PDT, DSL, or SRP. Pocket probing depth (PPD), bleeding on probing ... | 2011 | 22105837 |
| [initial study of biological characterization and virulence of porphyromonas gingivalis pg0839-defective mutant]. | to study the effect of pg0839 gene form porphyromonas gingivalis (p. gingivalis) on biological characterization and virulence in a murine model of soft tissue destruction, and further to provide evidence for clarifying the gene function of pg0839. | 2011 | 22109357 |
| [cloning and expression of peptidylarginine deiminase of porphyromonas gingivalis]. | to clone the peptidylarginine deiminase(pad) gene of porphyromonas gingivalis(p.gingivalis) and to be expressed in e. coli under the best conditions. | 2011 | 22109358 |
| tobacco smoke augments porphyromonas gingivalis-streptococcus gordonii biofilm formation. | smoking is responsible for the majority of periodontitis cases in the us and smokers are more susceptible than non-smokers to infection by the periodontal pathogen porphyromonas gingivalis. p. gingivalis colonization of the oral cavity is dependent upon its interaction with other plaque bacteria, including streptococcus gordonii. microarray analysis suggested that exposure of p. gingivalis to cigarette smoke extract (cse) increased the expression of the major fimbrial antigen (fima), but not the ... | 2011 | 22110637 |
| subgingival microbial consortia and the clinical features of periodontitis in adolescents. | this study aimed to investigate the association between microbial consortia and the clinical features of periodontitis using a multilevel modeling approach. a total of 958 sites in 87 adolescents with periodontitis (cases) and 73 controls were microbiologically sampled and clinically examined. associations between each of the clinical parameters clinical attachment, probing depth, supragingival plaque, calculus, bleeding on probing, and each of 18 bacterial species; and between the same clinical ... | 2011 | 22112031 |
| Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1ß or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signalling. | OBJECTIVE: Cigarette smoking is an important risk factor for periodontal disease. The aim of this study is to evaluate the effect of nicotine, a major component of cigarette smoke, on interleukin-8 (IL-8) production and cellular signalling via nicotinic acetylcholine receptors (nAChRs) in human gingival epithelial cells (HGECs). DESIGN: Messenger RNA (mRNA) expression of nAChR subunits in three different HGEC lines (epi 4, Tfx and E6E7) was assessed using reverse transcription-polymerase chain r ... | 2011 | 22119045 |
| Role of p38 MAPK Pathway in Porphyromonas gingivalis LPS-Induced VCAM-1 Expression in Human Aortic Endothelial Cells. | Background: Porphyromonas gingivalis lipopolysaccharide (LPS) has been reported to induce the expression of vascular cell adhesion molecule-1 (VCAM-1) in vascular endothelial cells. This finding suggests potential roles for P. gingivalis in the pathogenesis of atherosclerosis. However, the mechanism involved in P. gingivalis LPS-induced VCAM-1 production in endothelial cells remains unclear. Methods: Quantitative real-time polymerase chain reaction and Western blotting were used respectively to ... | 2011 | 22122523 |
| Porphyromonas gingivalis: a clonal pathogen?: Diversities in housekeeping genes and the major fimbriae gene. | The introduction of multilocus sequence typing (MLST) in infectious disease research has allowed standardized typing of bacterial clones. Through multiple markers around the genome, it is possible to determine the sequence type (ST) of bacterial isolates to establish the population structure of a species. For the periodontal pathogen, Porphyromonas gingivalis, the MLST scheme has been established at www.pubmlst.org/pgingivalis, and data from the database indicate a high degree of genetic diversi ... | 2011 | 22125739 |
| Improved periodontal health and cardiovascular risk. | Background: Previous studies have demonstrated variable effects on systemic inflammatory and immune responses following improved periodontal health. This study examined changes in serum levels of the inflammatory mediators IL-1ß, IL-6, TNF-a and sICAM-1, and antibodies to Porphyromonas gingivalis, human heat shock protein (hHSP) 60 and P. gingivalis GroEL following improvement in periodontal health in high cardiovascular (CV) risk and low CV-risk patients. Methods: Patients retrospectively sel ... | 2011 | 22126343 |
| thyrotoxicosis with post-treatment hypothyroidism in a patient with acute suppurative thyroiditis due to porphyromonas. | background: acute suppurative thyroiditis (ast) is a rare, life-threatening thyroid infection characterized by a tender neck mass and fever. as these features are shared with self-limited subacute thyroiditis (sat), it is important to differentiate between the two disorders. patient findings: we report a case of ast in a 21-year-old woman who presented with steadily worsening throat pain for 3 weeks, a tender left neck mass, and thyrotoxicosis. she was initially given prednisone for treatment ... | 2011 | 22136210 |
| the subgingival microbiota of papillon-lefèvre syndrome. | background: there is little information about the microbiological profiles of periodontal lesions in papillon-lefèvre syndrome (pls) and the significance of bacteria in the pathogenesis of periodontitis in these patients. this comprehensive analysis of the subgingival microbiota in pls patients used 16s rrna clonal analysis and the 16s rrna-based human oral microbe identification microarray (homim). methods: thirteen pls patients, from 7 unrelated families, volunteered for this microbiological s ... | 2011 | 22141356 |
| animal models to study host-bacteria interactions involved in periodontitis. | animal models have distinct advantages because they can mimic cellular complexities that occur in humans in vivo and are often more accurate than in vitro studies that take place on plastic surfaces with limited numbers of cell types present. furthermore, cause and effect relationships can be established by applying inhibitors or activators or through the use of genetically modified animals. such gain or loss of function studies are often difficult to achieve in human clinical studies, particula ... | 2012 | 22142960 |
| antimicrobial advances in treating periodontal diseases. | antibiotics are generally an efficient means of treating bacterial infections, and therefore are an obvious candidate in the treatment of periodontal diseases. systemically and locally administered antimicrobial agents of all kinds have been evaluated in multiple clinical trials. the vast majority of studies have tested antibiotics as adjuncts to non-surgical debridement. no regime has demonstrated superiority over systemically administered amoxicillin and metronidazole in the treatment of any c ... | 2012 | 22142961 |
| symptomatic and asymptomatic apical periodontitis associated with red complex bacteria: clinical and microbiological evaluation. | in this study, the association of red complex (rc) bacteria that include treponema denticola, tannerella forsythia and porphyromonas gingivalis with acute, exacerbated or chronic apical periodontitis was evaluated. seventy-one patients with periapical disease were evaluated by clinical examination and microbiological samples obtained from the root canals were analyzed by a polymerase chain reaction assay. twenty-one (29.6%) samples were positive for rc bacteria, with t. ... | 2011 | 22143381 |
| vima-dependent modulation of acetyl-coa levels and lipid a biosynthesis can alter virulence in porphyromonas gingivalis. | the poryphyromonas gingivalis vima protein has multifunctional properties that can modulate several of its major virulence factors. to further characterize vima, p. gingivalis fll406 carrying additional vima gene and vima-defective mutant in a different p. gingivalis genetic background were evaluated. the vima-defective mutant (fll451) in the p. gingivalis 33277 genetic background showed a similar phenotype to the vima-defective mutant (fll92) in the p. gingivalis w83 genetic background. in cont ... | 2011 | 22144476 |
| Free lipid A isolated from P. gingivalis LPS is contaminated with phosphorylated dihydroceramide lipids: Recovery in diseased dental samples. | Recent reports indicate that Porphyromonas gingivalis mediates alveolar bone loss or osteoclast modulation through engagement of Toll like receptor 2 (TLR2) though the factors responsible for TLR2 engagement have yet to be determined. LPS and lipid A, lipoprotein, fimbria and phosphorylated dihydroceramides of P. gingivalis have been reported to activate host cell responses through engagement of TLR2. LPS and lipid A are the most controversial in this regard because conflicting evidence has been ... | 2011 | 22144487 |
| [clinical effect of chitosan in bacterial vaginosis therapy]. | determination of antibacterial activity of acid-soluble chitosan in bacterial vaginosis therapy in women of reproductive age and comparison of therapy results of traditional scheme and local administration of acid-soluble chitosan. | 2011 | 22145355 |
| [Role of several periodontopathogenic microorganisms and tlr4 gene Asp299Gly polymorphism in atherosclerosis pathogenesis]. | Establishment of presence of periodonto-pathogenic microorganisms in atherosclerosis plaque and surrounding tissues, and possible relation of development of atherosclerosis and TLR4 gene Asp299Gly polymorphism in ischemic heart disease patients (IHD). | 2011 | 22145357 |
| anti-inflammatory effect of heme oxygenase-1 toward porphyromonas gingivalis lipopolysaccharide in macrophages exposed to gomisins a, g, and j. | periodontitis, a chronic inflammatory periodontal disease that develops from gingivitis, is caused by periodontal pathogenic bacteria such as porphyromonas gingivalis. recent studies have focused on the antioxidant, anti-human immunodeficiency virus, anticarcinogenic, and anti-inflammatory properties of gomisins. however, the anti-inflammatory activities of gomisin plants through heme oxygenase-1 (ho-1) signals remain poorly defined. we found that gomisins' anti-inflammatory activity occurs via ... | 2011 | 22145771 |
| Clinical and Microbial Evaluation of the Effects on Gingivitis of a Mouth Rinse Containing an Enteromorpha linza Extract. | Abstract Enteromorpha linza, a green alga, has been recognized as a potential source of natural antimicrobial and antifungal compounds. We previously reported that an E. linza extract strongly inhibited the growth of Prevotella intermedia and Porphyromonas gingivalis. The principal objective of this study was to evaluate the clinical effect of a mouth rinse containing the E. linza extract on gingivitis disease, as measured by the plaque index (PI), gingival index (GI), and bleeding on probing ... | 2011 | 22145775 |
| Aerosolized clindamycin is superior to aerosolized dexamethasone or clindamycin-dexamethasone combination in the treatment of severe Porphyromonas gingivalis aspiration pneumonia in an experimental murine model. | ABSTRACT Adjunctive corticosteroid treatment to reduce excessive local inflammatory response in pneumonia is controversial. To study the effects of an early local adjunct dexamethasone treatment on the course of pneumonia and inflammatory/cytokine response, mice were intratracheally inoculated with live Porphyromonas gingivalis and treated with either clindamycin (C), dexamethasone (D), C+D combination, or were not treated (Pg). Six mice from each group were euthanized at 6, 24, 72, and 168 ho ... | 2011 | 22149928 |
| extracellular deoxyribonuclease production by periodontal bacteria. | palmer lj, chapple ilc, wright hj, roberts a, cooper pr. extracellular deoxyribonuclease production by periodontal bacteria. j periodont res 2011; doi: 10.1111/j.1600-0765.2011.01451.x © 2011 john wiley & sons a/s background and objective: whilst certain bacteria have long been known to secrete extracellular deoxyribonuclease (dnase), the purpose in microbial physiology was unclear. recently, however, this enzyme has been demonstrated to confer enhanced virulence, enabling bacteria to evade the ... | 2011 | 22150619 |
| The adhesion of oral bacteria to modified titanium surfaces: role of plasma proteins and electrostatic forces. | OBJECTIVES: Modifications of titanium (Ti) implant surfaces have a significant effect on early biofilm formation and the outcome of implant procedures. The aim of this study was to examine the role of plasma proteins and electrostatic forces in the adhesion mechanism of oral bacteria to modified Ti surfaces. MATERIALS AND METHODS: Ti discs with three different types of surface modifications, machined, acid-etched, and acid-etched and blasted, were examined for adhesion of oral bacteria: Streptoc ... | 2011 | 22150723 |
| [enteric gram negative rods and unfermented of glucose bacteria in patients with peri-implant disease]. | implants can be colonized by microorganisms from oral biofilms and may affect peri-implant tissues health. among these bacteria, pathogens typically associated with periodontitis can be found, such as aggregatibacter actinomycetemcomitans and porphyromonas gingivalis, as well as gram negative enteric bacilli not typically associated with periodontal diseases. | 2011 | 22159480 |
| immune evasion strategies of porphyromonas gingivalis. | porphyromonas gingivalis is strongly correlated with chronic periodontitis. its chronic persistence in the periodontium depends on its ability to evade host immunity without inhibiting the overall inflammatory response, which is actually beneficial for this and other periodontal bacteria. indeed, the inflammatory exudate (gingival crevicular fluid) is a source of essential nutrients, such as peptides and hemin-derived iron. in this review, i discuss how p. gingivalis can promote its adaptive fit ... | 2011 | 22162663 |
| [quorum sensing inhibitor brominated furanone affects porphyromonas gingivalis biofilm formation]. | to study the influence of the quorum sensing inhibitor brominated furanone on porphyromonas gingivalis (p. gingivalis) biofilm formation. | 2011 | 22165111 |
| Oral Bacterial DNA Differ in Their Ability to Induce Inflammatory Responses in Human Monocytic Cell Lines. | BACKGROUND: DNA of periodontal pathogens, Porphyromonas gingivalis (Pg-DNA) and Tannerella forsythia, stimulate cytokine production in human monocytic cells (THP-1) through Toll like receptor 9 (TLR-9) and nuclear factor kappa B signaling. Fusobacterium nucleatum is one of the most frequently isolated bacteria in periodontally-diseased tissues and reported to synergize with Porhyromonas gingivalis enhancing the pathogenicity. We investigated inflammatory mediator production in THP-1 cells challe ... | 2011 | 22166166 |
| Quantitative analysis of microbiota in saliva, supragingival, and subgingival plaque of Chinese adults with chronic periodontitis. | OBJECTIVE: The aim of this study was to determine the profiles of periodontopathogenic bacteria in a Chinese population using quantitative real-time polymerase chain reaction (qRT-PCR). MATERIALS AND METHODS: Twenty-four periodontally healthy Chinese subjects and 60 patients with chronic periodontitis (CP) were enrolled in this cross-sectional study. qRT-PCR was used to quantify Aggregatibacter actinomycetemcomit ... | 2011 | 22169888 |
| relationship between serum antibody titres to porphyromonas gingivalis and hs-crp levels as inflammatory markers of periodontitis. | objective: the present study was designed to investigate whether titres of antibody to two strains of porphyromonas gingivalis, fdc381 and su63, are associated with serum high-sensitivity c-reactive protein (hs-crp) levels in japanese periodontitis patients. design: forty-nine patients with moderate to advanced periodontitis and 40 periodontally healthy control subjects were included in this study. hs-crp levels and antibody titres to p. gingivalis were measured at baseline and reassessment 3-4 ... | 2011 | 22172404 |
| bacterial-killing effect of atmospheric pressure non-equilibrium plasma jet and oral mucosa response. | recently, plasma sterilization has attracted increasing attention in dental community for the atmospheric pressure non-equilibrium plasma jet (apnps), which is driven by a kilohertz pulsed dc power, may be applied to the dental and oral diseases. however, it is still in doubt whether apnps can effectively kill pathogenic bacteria in the oral cavity and produce no harmful effects on normal oral tissues, especially on normal mucosa. the aim of this study was to evaluate the bacterial-killing effec ... | 2011 | 22173512 |
| [Effect of CD-14 and toll like receptors on the expression of interleukin-6 induced by lipopolysaccharides of Porphyromonas endodontalis]. | To evaluate the effect of cluster of differentiation 14 (CD-14) and Toll like receptors (TLR) on the expression of interleukin-6 (IL-6) mRNA induced by Porphyromonas endodontalis (Pe) lipopolysaccharides (LPS). | 2011 | 22177355 |
| Antimicrobial resistance determinants among anaerobic bacteria isolated from footrot. | Antibiotic resistance has been evaluated among 36 Gram negative and anaerobic bacilli (10 Bacteroides, 11 Prevotella, 7 Porphyromonas and 8 Fusobacterium strains) isolated from clinical cases of caprine and ovine footrot (necrotic pododermatitis). The initial analysis on this bacterial consortium evaluates the relationships existing among antimicrobial resistance determinants, phenotype expression and mobilization potential. The Bacteroides strains were generally resistant to penicillins, first- ... | 2011 | 22177890 |
| The periodontal pathogen Porphyromonas gingivalis induces the Epstein-Barr virus lytic switch transactivator ZEBRA by histone modification. | Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that usually results in latent infection of B cells. The EBV BZLF1 gene product ZEBRA is a master regulator of the transition from latency to the lytic replication cycle. In the latent state, hypoacetylation of histone proteins in the BZLF1 promoter by histone deacetylases (HDACs) is primarily involved in maintaining EBV latency. Although the mechanism that regulates the switch between latency and lytic replication has been a central res ... | 2011 | 22178321 |
| efficacy of locally-delivered doxycycline microspheres in chronic localized periodontitis and on porphyromonas gingivalis. | aim: this study aimed to assess the efficacy and effect of locally-delivered doxycycline microspheres with scaling and root planing in periodontal pocket therapy and on porphyromonas gingivalis, respectively. methods: twenty sites with a probing pocket depth of 4-6 mm were divided into two groups: a control group consisting of scaling and root planing, with one application of doxycycline microspheres only at baseline, and a test group consisting of scaling and root planing, with an application ... | 2011 | 22180217 |
| predominant bacterial species in subgingival plaque in dogs. | dahlén g, charalampakis g, abrahamsson i, bengtsson l, falsen e. predominant bacterial species in subgingival plaque in dogs. j periodont res 2011; doi: 10.1111/j.1600-0765.2011.01440.x.©2011 john wiley & sons a/s background and objective: the dog has been used extensively for experimental and microbiological studies on periodontitis and peri-implantitis without detailed knowledge about the predominant flora of the subgingival plaque. this study was designed to evaluate the predominant cultivab ... | 2011 | 22181039 |
| clarithromycin suppresses the periodontal bacteria-accelerated abdominal aortic aneurysms in mice. | aoyama n, suzuki j-i, ogawa m, watanabe r, kobayashi n, hanatani t, yoshida a, ashigaki n, izumi y, isobe m. clarithromycin suppresses the periodontal bacteria-accelerated abdominal aortic aneurysms in mice. j periodont res 2011; doi: 10.1111/j.1600-0765.2011.01454.x. © 2011 john wiley & sons a/s background and objective: although clarithromycin (cam) has many biological functions, including regulation of mmps, little is known about its effect on abdominal aortic aneurysms. periodontopathic bac ... | 2011 | 22181324 |
| Trefoil Factors in Saliva and Gingival Tissues of Patients With Chronic Periodontitis. | Background: Trefoil factors (TFFs) are secreted molecules which are involved in cytoprotection against tissue damage, and the immune response. TFFs have been detected in saliva and oral tissues, but their clinical significance has never been investigated in patients with chronic periodontitis. The objective of our study was to determine if TFF expression in saliva and gingival tissues was associated with periodontal pathology. Methods: Saliva and gingival tissue samples were collected from 25 n ... | 2011 | 22181686 |
| Microbiological analysis of gingivitis in pediatric patients under orthodontic treatment. | The aim of this study was to determine the relationship between gingival inflammation and changes in bacteria of the gingival sulcus in children in orthodontic treatment with brackets. | 2011 | 22185242 |
| In situ gastrointestinal protection against anthrax edema toxin by single-chain antibody fragment producing lactobacilli. | ABSTRACT: BACKGROUND: Anthrax is caused by the bacterium Bacillus anthracis and is regarded as one of the most prominent bioterrorism threats. Anthrax toxicity is induced by the tripartite toxin complex, composed of the receptor-binding anthrax protective antigen and the two enzymatic subunits, lethal factor and edema factor. Recombinant lactobacilli have previously been used to deliver antibody fragments directed against surface epitopes of a variety of pathogens, including Streptococcus mutan ... | 2011 | 22185669 |
| The destructive effects of butyrate on the cell envelope of Helicobacter pylori. | Helicobacter pylori can be detected in the oral cavity, although most studies involve the use of PCR techniques. The growth of H. pylori is influenced by various factors in the mouth such as the oral microflora, saliva and other antimicrobial substances, all of which make colonization of the oral cavity by H. pylori difficult. In this study, we analyzed the effect of the cell supernatant of a representative periodontal bacterium Porphyromonas gingivalis on H. pylori and found that the cell super ... | 2011 | 22194341 |
| a five-species transcriptome array for oral mixed-biofilm studies. | oral polymicrobial interactions and biofilm formation are associated with initiation and progression of caries, gingivitis, and periodontitis. transcriptome studies of such interactions, allowing a first mechanistic insight, are hampered by current single-species array designs. | 2011 | 22194794 |
| Solution NMR structures reveal a distinct architecture and provide first structures for protein domain family PF04536. | The protein family (Pfam) PF04536 is a broadly conserved domain family of unknown function (DUF477), with more than 1,350 members in prokaryotic and eukaryotic proteins. High-quality NMR structures of the N-terminal domain comprising residues 41-180 of the 684-residue protein CG2496 from Corynebacterium glutamicum and the N-terminal domain comprising residues 35-182 of the 435-residue protein PG0361 from Porphyromonas gingivalis both exhibit an a/ß fold comprised of a four-stranded ß-sheet, thre ... | 2011 | 22198206 |
| [Calcium metabolism associated with oral diseases. Cardiovascular diseases and periodontal diseases]. | Accumulated evidence has strongly suggested that the long-term effects of periodontal diseases can be linked to more serious systemic conditions such as cardiovascular diseases, diabetes, and complications of pregnancy. Especially, a prevalence of coronary heart disease was found to be significantly increased in patients with periodontitis after adjusting for risk factors such as smoking, diabetes, alcohol intake, obesity, and blood pressure. Furthermore, various studies have shown that Porphyro ... | 2012 | 22201098 |
| evidence for graft colonization with periodontal pathogens in lung transplant recipients. | summary bronchiolitis obliterans syndrome (bos) is a major cause of late graft dysfunction in lung transplant recipients. there is increasing evidence that beside alloimmunologic injury also non-alloimmunologic inflammatory conditions may raise the risk of acute and chronic rejection. the oral cavity represents a possible reservoir for pathogenic bacteria due to its close anatomical proximity. in this pilot study, the presence of pathogenic periodontal bacteria in the oral cavity as well as in t ... | 2011 | 22203528 |
| in vitro antibacterial activity of galls of quercus infectoria olivier against oral pathogens. | the galls of quercus infectoria are commonly used in malay traditional medicine to treat wound infections after childbirth. in india, they are employed traditionally as dental applications such as that in treatment of toothache and gingivitis. the aim of the present study was to evaluate the antibacterial activity of galls of quercus infectoria olivier against oral bacteria which are known to cause dental caries and periodontitis. methanol and acetone extracts were screened against two gram-posi ... | 2012 | 22203875 |
| Bactericidal properties of pradofloxacin against veterinary pathogens. | Pradofloxacin is a new veterinary 8-cyano-fluoroquinolone developed for use against bacterial infections in dogs and cats involving both aerobic and anaerobic bacteria. The minimal bactericidal concentrations have been determined against clinical isolates of Staphylococcus pseudintermedius, Staphylococcus aureus, Escherichia coli, Pasteurella multocida, Streptococcus canis, Proteus spp., Fusobacterium spp., Porphyromonas gingivalis and Prevotella species. A subset of these species was selected, ... | 2011 | 22209121 |
| full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial. | aim: the present investigation aimed to analyse clinical and microbiological effects of systemic administration of metronidazole and amoxicillin combined with the one-stage-full-mouth-disinfection protocol (osfmd) in generalized aggressive periodontitis patients (g-agp). materials and methods: thirty-nine systemically healthy patients with g-agp were consecutively included. the test group (n = 19) received amoxicillin-metronidazole combination (500 mg of each, three times a day for 7 days) and t ... | 2012 | 22220822 |
| the effects of bovine necrotic vulvo-vaginitis on reproductive and production performance of israeli 1st calf heifers. | bovine necrotic vulvovaginitis (bnvv) is a syndrome unique to israel characterized by necrotic lesion in the caudal vagina mainly in first calf heifers after calving, associated with porphyromonas levii. the objectives of this study were to analyze the impact of bnvv on reproductive performance, milk production and survival in the heard of first calf dairy heifers in affected farms, and to verify if the effects of bnvv are severity-dependent. for assessment of the severity level a scale of 4 deg ... | 2012 | 22225696 |
| periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid. | in periodontitis, an effective host-response is primarily related to neutrophils loaded with serine proteases, including elastase (ne) and protease 3 (pr3), the extracellular activity of which is tightly controlled by endogenous inhibitors. in vitro these inhibitors are degraded by gingipains, cysteine proteases produced by porphyromonas gingivalis. the purpose of this study was to determine the level of selected protease inhibitors in gingival crevicular fluid (gcf) in relation to periodontal i ... | 2012 | 22230465 |
| porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study. | although previous studies have shown the presence of porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated. | 2012 | 22232719 |
| impact of supragingival therapy on subgingival microbial profile in smokers versus non-smokers with severe chronic periodontitis. | the aim of this study was to assess subgingival microbiological changes in smokers versus non-smokers presenting severe chronic periodontitis after supragingival periodontal therapy (st). | 2012 | 22232720 |
| [effects of lipopolysaccharides from various porphyromonas on the expression of cd14 and tlrs in mouse osteoblast]. | to observe the effect of lipopolysaccharides(lps) extracted from porphyromonas endodontalis(p.e) and porphyromonas gingivals(p.g) on the expression of cd14 and tlrs in osteoblast. | 2011 | 22241307 |
| identification of the putative specific pathogenic genes of porphyromonas gingivalis with type ii fimbriae. | porphyromonas gingivalis, the key etiologic agent of periodontitis, can be classified into six types (i to v and ib) based on the fima genes that encode fima (a subunit of fimbriae). accumulated evidence indicates that p. gingivalis expressing type ii fimbriae (pg-ii) is the most frequent isolate from severe periodontitis cases and is more virulent than other types of p. gingivalis. however, during the pg-ii infection process, which specific virulence factors play the key role is still unclear. ... | 2012 | 22257441 |
| microbial profile of patients with periodontitis compared with healthy subjects. | objective: to define and compare the microbiologic profile of subgingival plaque in german patients with periodontitis (including aggressive and advanced chronic periodontitis) and healthy subjects and to determine significant association between isolates and clinical status. aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, and tannerella forsythia are major periodontal pathogens, though it is recognized that other species may also contribute to the pathogenesis of periodontal di ... | 2012 | 22257880 |
| assessments of salivary antioxidant activity using electron spin resonance spectroscopy. | objective: in recent years, the function of saliva has been focused on evaluation of general status. the relationship between salivary antioxidant activity and periodontal disease progression is unclear. the aim of this study is to assess the relationship between periodontal disease and salivary antioxidant activity towards various reactive oxygen species (ros) using electron spin resonance (esr) technique. methods: we demonstrated that whole saliva derived rats or human subjects scavenged ros s ... | 2012 | 22261034 |
| longitudinal assessment of pigtailed macaque lower genital tract microbiota by pyrosequencing reveals dissimilarity to the genital microbiota of healthy humans. | vaginal bacterial communities play an important role in human health and have been shown to influence hiv infection. pigtailed macaques (macaca nemestrina) are used as an animal model of hiv vaginal infection of women. since the bacterial microbiota could influence retrovirus infection of pigtailed macaques, the genital microbiota in 10 cycling macaques was determined by pyrosequencing. the microbiota of all macaques was poly-microbial with a median of 13 distinct genera. strikingly, the gen ... | 2012 | 22264029 |
| oral microbial biofilm stimulation of epithelial cell responses. | oral bacterial biofilms trigger chronic inflammatory responses in the host that can result in the tissue destructive events of periodontitis. however, the characteristics of the capacity of specific host cell types to respond to these biofilms remain ill-defined. this report describes the use of a novel model of bacterial biofilms to stimulate oral epithelial cells and profile select cytokines and chemokines that contribute to the local inflammatory environment in the periodontium. monoinfection ... | 2012 | 22266273 |
| periodontitis, porphyromonas, and the pathogenesis of rheumatoid arthritis. | epidemiological data indicate a link between rheumatoid arthritis (ra) and periodontal disease (pd). in vitro and in vivo studies have sought to dissect potential mechanisms by which pd may contribute to initiation and progression of ra. however, these are both multifactorial, chronic diseases, and their complex etiologies and pathogenesis themselves remain incompletely understood. could there really be an etiological link or does this simply represent a statistical coincidence muddied by common ... | 2012 | 22274780 |