Publications

long-term response to carbamazepine: a retrospective study.	carbamazepine is now used by many clinicians in the treatment of bipolar disorder (bd) refractory to standard treatments, including lithium and neuroleptics. little information is yet available about the utility and efficacy of this novel treatment during long-term use. we carried out a retrospective study of 50 patients (34 with bd) who had received carbamazepine for the treatment of a psychotic disorder. two-thirds (22) of the bd patients and two of the 16 patients with other diagnoses appeare ...	2012	3372707
anticonvulsant effects of dextrorphan in rats: possible involvement in dextromethorphan-induced seizure protection.	the major metabolite of the non-opioid anticonvulsant/antitussive dextromethorphan is dextrorphan. in the present study, the effects of dextrorphan were determined in an experimental model of seizure activity (maximal electroshock convulsions) (mes). subcutaneous administration of dextrorphan produced dose-related blockade of tonic hindlimb extension (the) and a decrease in the duration of tonic forelimb extension (tfe). the anticonvulsant effect of dextrorphan was linear and maximally efficacio ...	1988	3374269
a highly active soluble diacylglycerol synthesizing system from developing rapeseed, brassica napus l.	the subcellular distribution of the enzymes of triacylglycerol biosynthesis has been studied in developing oilseed rape. all in vitro enzymatic activities from oleoyl-coa to triacylglycerol were sufficient to account for the known rate of oleate deposition in triacylglycerol in vivo. the enzymatic activities from oleoyl-coa to diacylglycerol preferentially were localized in a 150,000 g supernatant fraction, while the diacylglycerol acyl-transferase mostly was associated with the microsomal (20,0 ...	2012	3374270
nature of polymorphism in hla-a, -b, and -c molecules.	diversity in 39 hla-a, -b, and -c molecules is derived from 20 amino acid positions of high variability and 71 positions of low variability. variation in the structurally homologous alpha 1 and alpha 2 domains is distinct and may correlate with partial segregation of peptide and t-cell receptor binding functions. comparison of 15 hla-a with 20 hla-b molecules reveals considerable locus-specific character, due primarily to differences at polymorphic residues. the results indicate that genetic exc ...	2012	3375250
smooth the way for safe emergency transfers.		2012	3375752
[look for a career in psychiatry, you too!. interview by kjell arne bakke].		2012	3376002
thoraco-abdominal injuries in combat casualties on the cambodian border.	this article deals with the experience in the management of combined thoraric and abdominal injuries caused by combat casualties, and is based on experience gained in the international committee of the red cross (icrc) hospital in khao-i-dang, thailand. during a 3 month period a total of 123 patients injured by various battle conditions at the thailand-cambodian border were admitted to the icrc hospital. the thorax was involved in 31 patients, but only 8 of these had a combination of thoracic an ...	2002	3376087
accessory valve cusp as a cause of outflow tract obstruction in atrio-ventricular and ventriculo-arterial discordance.	congenital corrected transposition of the great arteries in which there is both an atrio-ventricular and a ventriculo-arterial discordance has surgical significance only in consequence of the associated cardiac anomalies. their surgical correction is subject to multifarious problems. an exceedingly rare cause of a left-ventricular outflow tract obstruction erroneously interpreted preoperatively in an eight-year-old boy is reported. in an l-transposition with inversion of both ventricles, the dia ...	2002	3376088
fiberoptic angioscopy of cardiac chambers, valves, and great vessels using a guiding balloon catheter in dogs.	the applicability of fiberoptic angioscopy with a guiding balloon catheter to observe the cardiac chambers, valves and the great vessels was examined in anesthetized dogs. a no. 11 french guiding balloon catheter (balloon diameter 50 french) was introduced through either the right jugular vein or the right femoral vein into the right heart, and then a fiberscope (4.3 french in diameter) was introduced through the catheter into the right heart in 10 dogs. the balloon was inflated with air and gen ...	1988	3376848
[acute hepatitis: prevention and treatment].		1988	3377335
keratophakia and keratomileusis.		2012	3378864
1 in 4 irish women suffer bone disease.		2012	3378870
artificial insemination with cryopreserved donor semen: a decade of experience.	ten years' experience of artificial insemination with cryopreserved donor semen for 1023 courses in 783 women resulting in 572 pregnancies is reported. a simple approach with multiple inseminations timed on the basis of cycle length, temperature charts, mucus symptoms and signs was used. the life table pregnancy rate was 61% after 12 cycles of treatment and 75% after 24 cycles. women had a significantly higher rate of pregnancy in second and subsequent courses of treatment, and the pregnancy rat ...	2012	3382608
electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons.	the effects of cocaine and procaine on the spontaneous activity of serotonin (5-hydroxytryptamine, 5-ht) neurons in the dorsal raphe nucleus of the chloral hydrate anesthetized male rat were characterized using extracellular single-unit and microiontophoretic recording techniques. intravenous cocaine elicited a potent, dose-dependent inhibition of 5-ht cell firing with a cumulative dose to 50% inhibition of cell firing of 0.66 +/- 0.11 mg/kg (means +/- s.e.m.; n = 17). in contrast, systemic admi ...	1988	3384007
[comparison of permanent cardiac pacing and cardiac pacing on demand in mixed carotid sinus syndrome. acute- and medium-term follow-up study].	the aim of the study was to evaluate the importance of atrial synchronism for pacing therapy of patients with mixed carotid sinus syndrome. on 23 patients (21 m, 2 f; mean age 69 +/- 8 years) affected by symptomatic mixed carotid sinus syndrome we performed: 1) the study of ventriculo-atrial conduction, 2) the evaluation of pacemaker effect and 3) the carotid sinus massage in standing position during vvi and dvi temporary pacing. all patients received a permanent dvi pacemaker and then underwent ...	2012	3384245
variations on burow's grafts.		2012	3385035
antibody response of an elderly population to a supplemental dose of influenza b vaccine.	recent reports have suggested that the antibody response of elderly persons to standard doses of influenza vaccine is depressed. we examined the effect of an additional threefold dose of influenza b vaccine on the antibody response in elderly, ambulatory veterans. one hundred thirty-one male subjects aged 70 years and older were randomized to receive one of three influenza vaccine regimens: group i received standard trivalent influenza vaccine containing 15 micrograms of b/ussr/100/83 in one arm ...	1988	3385111
stop and smell the roses along the way.		2012	3385634
insights on death & dying. depression: bottled-up emotions.		2012	3386914
risk factors for infantile recurrent otitis media: atopy but not type of feeding.	we followed 183 infants from birth to 2.3 yr of age. of these infants 28 had recurrent otitis media (rom), defined as five or more separate episodes of otitis media (om) during the first 2 yr of life or four such episodes during their 2nd yr. the om presented during their 1st yr (early-onset rom) in 12 infants and during their 2nd yr (2nd yr rom) in 16. eighty infants had no om and served as a comparison group. regarding type of feeding, the infants with early-onset rom did not differ from their ...	2012	3387173
if new graduates went to the community first.		2012	3387252
[study of the effect of antitumor agents on cell cycle traverse by flow cytometry].	the effect of antitumor agents on the cell cycle traverse of cultured fl cells, a monolayer culture line derived from human amnion, was investigated by flow cytometry (fcm) in combination with simultaneous determination of total cell number, viability, mitotic index and labeling index by [3h]tdr. the results obtained can be summarized as follows: antimetabolites prolonged the duration of the s phase at a low dose, while at a high dose they decreased the rate of progression from the g1 to s phase ...	1988	3389824
taurine prevention of calcium paradox-related damage in cardiac muscle. its regulatory action on intracellular cation contents.	the present study was designed to investigate in chick heart whether oral pretreatment with taurine or taurine added directly to the perfusate has any effect upon calcium paradox-induced heart failure. in both protocols, taurine significantly reduced the mechanical dysfunction resulting from the calcium paradox. taurine pretreatment partially inhibited the excess accumulation of calcium in the myocardium that occurs upon calcium repletion, and microscopy revealed almost normal structure. this pr ...	1988	3390225
cadmium-substituted skeletal troponin c metal binding investigations and sequence assignment of the cadmium-113 resonances.	the binding of cadmium to the calcium binding subunit of skeletal troponin (stnc) has been reinvestigated using direct binding methods and fluorescent derivatives. these data provide straightforward explanations of the observed titration behavior in the 113cd nmr (ellis, p.d., strang, p., and potter, j.d. (1984) j. biol. chem. 259, 10348-10356). further, fluorescent derivatives of skeletal troponin c provide an excellent means of establishing a sequence assignment for the resonances observed in ...	1988	3392014
intraoperative monitoring of evoked potentials with a spiral scalp electrode. technical note.	monitoring evoked potentials from the brain for prolonged periods during neurosurgical procedures ideally requires attached scalp electrodes that may be placed in a sterile field. the limitations of conventional surface and percutaneous electrodes in the operating room environment have led to the development of a disposable curved-needle electrode which is inherently self-retaining. clinical results have demonstrated the advantages of this new electrode over other electrodes currently used for i ...	2012	3394015
[the differentiation of bordetella bronchiseptica strains. 7. phenotypic changes in bordetella bronchiseptica through changes of phase].		1988	3395180
representation of forelimb mechanoreceptors within the superior colliculus of the cat.	forelimb mechanoreceptor representation within the superior colliculus was investigated using microelectrode recording in decerebrate or anaesthetized cats. selective activation of different mechanoreceptive fibre classes supplying the distal forelimb revealed a poor representation of all three fibre classes (sa, pc and ra) that innervate the glabrous skin. furthermore, there was no evidence for pacinian (pc) input from the interosseous or wrist region. the tap stimuli which are often needed to ...	1988	3399131
popliteal artery injury complicating arthroscopic menisectomy.	inadvertent popliteal artery injury during arthroscopic menisectomy is an unusual occurrence. prompt diagnosis and treatment are essential to achieve a good outcome, as illustrated in two of the five patients described herein. pitfalls in diagnosis led to late recognition and therapy in three patients, with subsequent serious complications; namely, arteriovenous fistula, false aneurysm, and amputation. on the basis of this limited but poignant experience, we propose an outline of steps in manage ...	2012	3400813
pharmacokinetics and pharmacodynamics of single oral doses of ibopamine, quinidine and their combination in normal man.	the pharmacokinetics and haemodynamics (phono- and impedance cardiography) of single oral doses of 200 mg ibopamine (sk&f 100168), 400 mg quinidine sulphate, and their combination, have been assessed in 6 healthy male volunteers. no significant differences in the mean pharmacokinetic parameters of either drug were seen between the single and combined doses. ibopamine caused an increase in mean estimated stroke volume (sv +29% for the maximum change from baseline and +15% cumulatively over the fi ...	1988	3402527
patton's utilization-focused evaluation as the basis of the quality assurance process.		2008	3403687
individual knowledge of emotions in asthmatic children.		2009	3404488
individual knowledge of emotions in asthmatic children.		2009	3404488
information systems for the community health services.	this paper is concerned with the design and implementation of an information system which fulfils some of the local needs of fourteen nursing and para-medical professions working in the community in a district health authority, whilst satisfying the statutory requirements of the nhs körner steering group for those professions. the implementation of the computer information system was achieved through the participation of those professionals who would eventually use the system. a prototype system ...	2012	3405016
health care delivery to adolescents and young adults by pediatricians.		2012	3405691
[obstacle to left ventricle ejection after mitral valvular replacement with a carpentier-edwards bioprosthesis. apropos of 2 cases].	impairment of the left ventricular ejection induced by a mitral prosthesis remains an infrequent complication, perhaps because it often is unrecognized. this complication would mainly be seen with ball prostheses or standard bioprosthesis used in mitral valve replacements with a small ventricle. two cases have been recently reported during mitral valve replacement. the two patients were successfully re-operated upon, one after five weeks and the second immediately after the first procedure. a re ...	2012	3408199
vitamin a in osteo- and rheumatoid arthritis.		2012	3408838
expression of fibronectin on clonally related transformed and control sublines from an epithelial cell strain and a tumor line of mouse alveolus.	the cellular expression of fibronectin and the importance of fibronectin for the morphology of cultured cells were studied in a lung epithelial cell system. the cells used were clonally related control nal1a, spontaneously transformed nal1as cells of the nal1a cell strain, and transformed clonal sublines of the cell line nal1am and the tumor cell line nul1. fibronectin was detected on the surface of nal1a cells by surface iodination; fibronectin synthesis, secretion, and pericellular accumulatio ...	1988	3409226
effect of cessation of alcohol use on the course of pancreatic dysfunction in alcoholic pancreatitis.	exocrine pancreatic function was studied sequentially by means of the secretin-cerulein test in 32 patients with alcoholic chronic pancreatitis to elucidate the long-term course of pancreatic dysfunction, and to determine whether the cessation of alcohol use had any influence on the natural history of pancreatic functional changes caused by this disease. at initial studies, 5 patients had normal pancreatic function, and the remaining 27 had pancreatic insufficiency, which was mild to moderate in ...	2012	3410221
crystallographic structure and surface morphology of sintered carbonated apatites.	densely sintered synthetic hydroxyapatite (ha) is used as an implant material because of its excellent tissue biocompatibility. in order to maximize the biological potential of this calcium phosphate, we have investigated the incorporation of carbonate into ha to make a material which more closely resembles the mineral found in bones and teeth. the aim of the present study was to determine the conditions under which sintered carbonated apatites of specific carbonate content could be produced. th ...	2012	3410872
aspiration following stroke: clinical correlates and outcome.	among 47 patients with stroke evaluated clinically and videofluoroscopically, one-half aspirated. patients with combined cerebral-brainstem strokes with bilateral cranial nerve signs were at greatest risk, but aspiration also occurred in the context of unilateral signs. dysphonia was the common clinical characteristic of aspirating patients. single chest roentgenograms were of limited value in predicting aspiration. outcome was favorable following compensatory oral feeding programs.	2012	3412582
the professional ethics and practice committee: a step toward the achievement of excellence.		2012	3412661
erythrocyte incorporation of ingested 58-iron by infants.	the least abundant stable isotope of iron, 58fe (natural abundance 0.322 weight %), was administered orally to infants to explore the feasibility of using a stable rather than a radioisotope in studies of iron absorption. the dose of 58fe was given between feedings at age 126 days. the mass isotope ratio, 58fe/57fe, was determined in blood by inductively coupled plasma mass spectroscopy and at ages 140, 168, and 196 days. the percentage of the 58fe dose entering the circulation (3.2 to 16.0%) wa ...	2012	3412846
course and transformation of polycythaemia vera in relation to therapy.	the fate of the polycythaemic patient depends on the treatment employed which may determine the nature of the transformation commonly occurring late in the course of the disease. treatment is, on the other hand, aimed at prevention of the most frequent complications, that is of thromboembolic processes. in the last 30 years the authors treated a total of 118 pv patients, of whom 60 have died. initially 32p treatment was applied, which was modified later, because of acute leukaemia that had occur ...	2012	3412864
a new constrictor device for external induction of a long-term stable and irreversible renal artery stenosis in the dog.	a new externally adjustable constrictor device for renal artery stenosis in the dog is described. the constrictor combines hydraulic and mechanical characteristics, and is connected to the exterior of the animal by a thin catheter. applying hydraulic pressure via the catheter causes the plunger in the device to compress the renal artery to any desired degree of stenosis. a mechanical catch prevents backward movement of the plunger, thus ensuring a stable, irreversible renal artery constriction. ...	1988	3412870
[certification of laboratories of the sanitary and epidemiological stations].		2012	3413534
[diarrhea in the 1st month of life. retrospective study of 53 cases with exclusion-reintroduction trial of cow's milk].		2012	3415160
production of a positive direct antiglobulin test due to suramin.	drugs and chemicals containing multiple reactive carbonyl groups have been postulated to produce nonimmunologic positive direct antiglobulin tests (dats) both in vitro and in vivo. suramin sodium, a reverse transcriptase inhibitor that was under investigation as a potential treatment for human immunodeficiency virus infection, has six reactive carbonyl groups. because of suramin's chemical structure, it was hypothesized that the drug might cause a positive dat in vitro and possibly in vivo. sura ...	1988	3415441
[dynamics of folliculogenesis in the mouse ovary after the intrauterine elimination of germ cells by administering cyclophosphamide].	injection of cytostatic--cyclophosphamide--to pregnant mice produces elimination of germ cells in their offspring ovaries. independently on the elimination degree of the germ cells, the amount of growing follicles, as well as dynamics of their growth do not differ from those in the majority of control (intact) animals. in some cases the delay in the rate of the follicular growth is connected with regional outgrowth of the interstitial tissue. this, in its turn, depends on uneven distribution of ...	1988	3415486
metabolism of acetylene and acetaldehyde by rhodococcus rhodochrous.	we studied the ability of a soil bacterium, identified as rhodococcus rhodochrous, to grow on acetylene and to accumulate acetaldehyde. its maximum growth rate on acetylene was obtained at about 30 degrees c (mu = 0.11 h-1) and was independent of the concentration of this gas in air from 0.14 to 16% (v/v). during growth, acetylene was quantitatively transformed to acetaldehyde, ethanol, acetate, co2, and biomass in proportions which varied with culture age and temperature. growth was completely ...	1988	3416237
notifiable diseases in canada.		2012	3416266
immunosuppressive substance in the sera of head and neck cancer patients.	serum levels of immunosuppressive substance (is) and immunosuppressive acidic protein (iap) were studied by single radial immunodiffusion in 108 patients with head and neck cancer. mean values of serum is and iap in patients with head and neck cancers were as follows: laryngeal carcinoma, 955 +/- 447 micrograms/ml (is), 604 +/- 324 micrograms/ml (iap); maxillary carcinoma, 896 +/- 384 micrograms/ml (is), 568 +/- 246 micrograms/ml (iap); nasopharyngeal carcinoma, 871 +/- 313 micrograms/ml (is), 6 ...	1988	3416271
patterns of lactate dehydrogenase isoenzymes in serum of patients with acute pulmonary edema.	total lactate dehydrogenase (ld; ec 1.1.1.27) activity in serum and proportions of ld isoenzymes were quantified on admission and discharge in 170 selected (from 240) patients with acute pulmonary edema (ape). the patients were divided into group a, 75 patients with normal ld values (less than 225 u/l); and groups b-e, with increased ld activity in serum: group b, 40 patients with increase in the proportion of ld-3 (greater than 38%); group c, 12 patients with increased ld-5; group d, 36 patient ...	2012	3416439
"urin-pak" immunoturbidimetric method evaluated for measuring albumin in urine.		2012	3416465
adenosine deaminase in the acquired immunodeficiency syndrome.		2012	3416480
fast functional assay of protein c in whole plasma using a snake venom activator: evaluation in patients with congenital and acquired protein c deficiencies.	both anticoagulant and amidolytic activities of protein c (pc) were measured using a snake venom activator in 4 patients with hereditary pc deficiency, 37 with disseminated intravascular coagulation (dic), and 30 under stabilized warfarin therapy. the results were compared with those obtained by an immunological assay (elisa). pc levels measured by different functional and immunological assays were very close in patients with hereditary pc deficiency and dic. in patients under stable oral antico ...	2012	3416483
the regional variability of enzymes in the brain: relevance to csf enzyme determinations.	the assay of cerebrospinal fluid (csf) enzymes has been suggested for assessing the extent of damage and patient prognosis in cases of brain injury. a potential difficulty associated with using csf enzyme levels as predictors of outcome is the possibility that enzyme concentrations may vary substantially from one brain region to another. we have determined the concentrations of seven enzymes in seven brain regions in the rat and cat. acid phosphatase (acp), aspartate aminotransferase (ast), isoc ...	1988	3416484
biologic fixation of a press-fit titanium hip joint endoprosthesis.	the rectangular cross section of a straight-stem prosthesis makes a primary stable, rotation-safe fixation possible that is independent of the individual form of the femur. due to the curvature of the femur, a three-dimensional large-area anchorage is achieved along the entire prosthesis length in the corticalis as well as in the spongiosa. the titanium-aluminum-niobium alloy is extremely biocompatible and enables the fast ongrowth of newly formed osseous tissue to act as secondary stabilization ...	2012	3416526
juvenile rheumatoid arthritis: clinical characteristics in 100 thai patients.	the clinical characteristic of 100 patients diagnosed for jra at the department of pediatrics, ramathibodi hospital, bangkok, thailand during 1968-1984 are reported. there were 64 male and 36 female patients with a respective ratio of 1.7:1. in ninety-one percent the age of onset was over the age of five, the most common type being polyarticular onset (77%) followed by pauciarticular onset (13%) and systemic onset (10%). twenty percent had a positive rheumatoid factor and 4% had cardiac complica ...	2012	3416569
experimental contact sensitization with 3,4,5-trichloropyridazine.	the potential of 3,4,5-trichloropyridazine to induce contact sensitization was assessed in the guinea pig maximization test of magnusson and kligman and also in the closed patch test described by buehler. the test material was a 1% solution of 3,4,5-trichloropyridazine in a highly refined mineral oil. the test material elicited moderate to severe irritation when diluted in mineral oil to concentrations of 15-25% and minimal irritation at concentrations of 1-3%. both tests clearly indicated that ...	1988	3416588
effect of retinoids on the proliferation, morphology and expression of glial fibrillary acidic protein of an anaplastic astrocytoma cell line.	we studied the effect of retinoids on the growth and differentiation of a cell line (u 343 mg-a) derived from a human malignant astrocytoma. cultures treated with all-trans or 13-cis retinoic acid showed a dose-dependent inhibition of proliferation and a marked reduction in the mean cell number at the plateau phase of growth (3.5 x 10(6) vs. 1 x 10(7) cells/25 cm2) compared with untreated cultures. at confluence, cells treated with all-trans or 13-cis retinoic acid were contact-inhibited, wherea ...	1988	3417370
effect of gamma irradiation on the protoscoleces of echinococcus granulosus of sheep origin.		1988	3417384
internal pars plana sclerotomy with the contact nd:yag laser: an experimental study.	transvitreal pars plana sclerotomy using the contact nd:yag laser with a sapphire probe was performed on a group of rabbit eyes and compared with a similar procedure performed with a ziegler knife. although the intraocular pressure (iop) was lowered in both groups of animals, the reduction was greater and more lasting in the group on which the nd:yag laser with sapphire probe was used. this technique may have application in cases with extensive peripheral anterior synechiae or where a vitrectomy ...	1988	3417390
the relevance of transcultural nursing to international nursing.	does transcultural nursing as taught in united states' nursing education programmes adequately prepare us nurses for experiences in international health as they assist with the implementation of changes in another country's health care delivery system? that's the question posed by lydia desantis, who is concerned that us nurses need a broader perspective of health care and culture in order to effect changes needed at the national level of policy and decisionmaking to meet the challenges of the d ...	2012	3417392
how to develop tomorrow's nursing leaders.	a pivotal event for nursing was the "international encounter on leadership in nursing for health for all" in tokyo, japan, in april 1986. here, nursing leaders from every corner of the globe exchanged views and were spurred on to create a movement to achieve who's "health for all" goal. finally, after a long wait for permission to print, inr offers its readers one such view given at the conference. this paper gives not only advice on how to prepare tomorrow's nursing leaders in hfa but also an a ...	2012	3417396
optic disc, cup and neuroretinal rim size, configuration and correlations in normal eyes.	four hundred and fifty-seven unselected normal human optic nerve heads of 319 subjects (163 men, 156 women, mean age 42.7 +/- 19.6 years) were evaluated by magnification-corrected morphometry of optic disc photographs. mean optic disc surface measured 2.69 +/- 0.70 mm2 (0.80-5.54 mm2), mean diameter horizontally 1.76 +/- 0.31 mm (0.91-2.61 mm), and vertically 1.92 +/- 0.29 mm (0.96-2.91 mm). the form was slightly vertically oval. optic cup area averaged 0.72 +/- 0.70 (0.00-3.41 mm2), mean horizo ...	1988	3417404
hypotheses on exercise-induced pulmonary hemorrhage in horses.		1988	3417533
folk images of health and menstrual patterns among newfoundland outport women.		2012	3417577
induction and maintenance of swallowing responses in infants with dysphagia.	a treatment package was used to induce and maintain swallowing with three infants who did not swallow food or liquid. prior to treatment, they received all nutrition and hydration via gastrostomy tube feedings. the treatment package consisted of least-to-most intrusive physical prompts, an eliciting stimulus, contingent social reinforcement, and repeated trials to induce and maintain swallowing. the design combined elements of reversal and changing criterion designs for all three infants. the pa ...	2012	3417578
crystallization of trimeric recombinant human tumor necrosis factor (cachectin).	crystals of tumor necrosis factor (tnf) have been obtained in two forms. rhombohedral crystals grow in 1.8 to 2.0 m ammonium sulfite, ph 7.8 at 21 degrees c, and tetragonal crystals grow in 2.6 m magnesium sulfate, ph 5.5 at 25 degrees c. analysis of tnf by isoelectric focusing under native and denaturing conditions indicates that tnf molecules exist as trimers in solution. the rhombohedral cachectin crystals belong to space group r3 and have unit cell constants a = b = c = 47.65 a and alpha = b ...	1988	3417634
familial abdominal aortic aneurysms.		2012	3418662
the fate of venous repair after shock and trauma.	to assess the role of shock and trauma in the subsequent thrombosis of a venous repair, the following experiments were performed. two groups of unsplenectomized dogs were studied: control dogs (gr.c) underwent replacement of a segment of superficial femoral vein by an autogenous vein graft. trauma group (gr.t) dogs were subjected to hypovolemic shock using a modified wiggers' technique and received standardized hindleg trauma. after resuscitation, venous repairs identical to gr.c dogs were perfo ...	1988	3418758
product liability guide. the consumer protection act 1987 and the occupational health nurse.		2009	3419750
pharmacokinetics of bupivacaine after short and prolonged infusions in conscious dogs.	a conscious dog model was used to study pharmacokinetics of bupivacaine after a short infusion (si) (15 min) and a prolonged infusion (pi) (24 hours). bupivacaine was infused in six mongrel dogs at least 10 days after implantation of femoral arterial and venous catheters. each dog received both the si and the pi in a random crossover design at a one week interval. bupivacaine concentration was measured in serum sampled during the si, during the last hour of the pi, and at frequent intervals duri ...	1988	3421499
experimental evaluation of the mitroflow pericardial heart valve prosthesis. part ii. pathologic examination.	the results of the morphologic and histopathologic examination of 37 bovine pericardial heart valve prostheses that were retrieved after experimental implantation in chacma baboons for periods of one to twelve months are presented in this study. the implanted prostheses consisted of 33 mitroflow valves, size 21 mm, that belonged to four different groups according to the method of preparation of the pericardium (process i to iv) and 4 commercially available ionescu-shiley valves, size 19 mm. all ...	1988	3421507
native genomic blotting: high-resolution mapping of dnase i-hypersensitive sites and protein-dna interactions.	dnase i-hypersensitive sites are observed in the promoter regions of actively expressed genes, potentially active genes, and genes that were once active. we have developed an approach that greatly increases the resolution for mapping these sites by electrophoresing genomic dna on native polyacrylamide gels prior to electroblotting and hybridization. this improved method has been used to scan the promoter and coding region of a cell-cycle-dependent human histone h4 gene with an accuracy of +/-5-1 ...	1988	3422413
ketone-body metabolism in hyperthyroid rats: reduced activity of d-3-hydroxybutyrate dehydrogenase in both liver and heart and of succinyl-coenzyme a: 3-oxoacid coenzyme a-transferase in heart.	the specific activity of d-3-hydroxybutyrate dehydrogenase is reduced by about a third in liver and heart mitochondria of hyperthyroid rats. state 3 respiration is also reduced in isolated mitochondria from the same animals when dl-3-hydroxybutyrate is the substrate. determination of the kinetic parameters of the membrane-bound d-3-hydroxybutyrate dehydrogenase in liver of hyperthyroid rats reveals a decreased in maximal velocity (vmax). the michaelis and dissociation constants of nad+ and d-3-h ...	1988	3422549
the visualization of diagnostic images.		2012	3423331
[levels of plasma pseudocholinesterase in chronic renal insufficiency patients and hemodialysis].		2012	3423372
[erythrocyte longevity in hypoplastic anemia patients undergoing splenectomy as part of combined treatment].	a study was made of the survival time of erythrocytes labeled with 51cr in 30 patients with hypoplastic anemia. in 96.7% of the patients erythrocyte survival time was reduced (from 18 to 3.6 days; an average of 11.8 days), an increase in the number of macrocytes was noted (in 83.3%). the mean volume and thickness of erythrocytes were also on an increase (in 95.8%); a decrease in the spherical index of erythrocytes was noted (in 91.6%). in this connection erythrokaryocyte proliferation enhancemen ...	2012	3424200
femoral component loosening in hip arthroplasty. cadaver study of subsidence and hoop strain.	to aid in understanding loosening following cemented total hip arthroplasty, we conducted a cadaver study of the proximal femur with implanted cobalt-chromium and titanium femoral components of recent design, loaded through the head of the prosthesis. stem subsidence and strain in the proximal femur were measured. after proximal support of the implant collar was removed, we found that cobalt-chromium implants had a greater tendency to subside than titanium implants. subsidence of a femoral compo ...	2012	3425274
[gonadotropin, thyrotropin and thyroid hormone levels in patients with genital endometriosis during the menstrual cycle].		2012	3425833
[comparison of different campylobacter-selective media in the study of feces samples of domestic animals].		1987	3426537
neutron scattering determination of the binding of prothrombin to lipid vesicles.	low-angle neutron scattering is used to study the binding of human prothrombin to small single-bilayer vesicles consisting of phosphatidylcholine and phosphatidylserine (1/1 w/w). the radius of gyration of prothrombin indicates that it is an elongated molecule. the vesicles alone were not observed to coalesce, and their molecular weight, outer radius, and average surface area per lipid were respectively (1.6 +/- 0.32) x 10(6), 114 +/- 4 a, and 110 +/- 18 a2. these values were independent of the ...	1987	3427105
modulation of the defective natural killer activity seen in thalassaemia major with desferrioxamine and alpha-interferon.	we previously observed that natural killer (nk) activity toward k562 cells is markedly depressed in patients with beta-thalassaemia major. here we report that these patients also exhibit significantly decreased (p less than 0.005) nk cytotoxicity against human fibroblasts infected with herpes simplex virus-type 1 (hsv-1) and that the amount of alpha-interferon (alpha-ifn) generated during the latter assays is significantly less than normal (p less than 0.005). this decreased production of alpha- ...	1987	3427826
an empirical evaluation of a model geropsychiatric nursing home.		2009	3428627
an empirical evaluation of a model geropsychiatric nursing home.		2009	3428627
[pathogenesis of dilated cardiomyopathy: a study based on comparison of the clinical features with other related conditions].	to investigate the pathogenesis and pathophysiology of dilated cardiomyopathy (dcm), we studied 28 patients with dcm by echocardiography and endomyocardial biopsy, and compared their findings with those of 34 patients including eight with myocarditis, seven with alcoholics, 12 with hypertensives and seven patients with hypertrophic cardiomyopathy. all 12 patients in the hypertensive group had congestive heart failure without accompanying high blood pressure, and prominent dilatation and uniform ...	2012	3429922
delivery of theophylline into excised human skin from alkanoic acid solutions: a "push-pull" mechanism.	human skin samples are permeable to theophylline delivered from 1.5% solutions in various alkanecarboxylic acids and their mixtures. the respective permeability coefficients of theophylline, calculated from steady-state flux, correlate negatively with the permeability coefficients of the donor carboxylic acids and positively with the excess free energy of theophylline in the donor phase, or "push" effect. an exception is propionic acid which enhances the penetration of theophylline by promoting ...	1987	3430340
localization of source of immunosuppressive factor in the human male reproductive tract.	the source of the immunosuppressive factor (isf) in the human male reproductive tract which suppresses various in vitro immune responses has been identified. we describe here the prostatic localization of this factor, based on investigating the fractions of split ejaculates, ejaculates of individuals with blocked epididymis and the secretions of the prostate obtained by prostatic massage.	1987	3430481
safety considerations regarding the use of propane and other liquefied gases as coolants for rapid freezing purposes.	liquid propane and similar coolants are used in the rapid freezing of biological specimens. these coolants form explosive gas mixtures with air, with a 14,000-fold increase in volume over that of the liquid. the liquefied gases have high vapour pressures and, unless they are maintained below their flashpoint, the vapour above them will reach ignitable concentrations. the flashpoint of liquid propane is -104 degrees c. ethane has a higher vapour pressure, and vapour mixed with air above liquid et ...	2012	3430580
[effect of halothane anesthesia on the blood circulation of the skin in children with burns].		2008	3430985
[a new measurement of pulmonary venous compliance by r-synchronized volume loading].		1987	3432757
[use of nonparametric statistical criteria in epidemiological research].	the article deals with the possibility of using two nonparametric statistical methods (sign criterion, wilkonson's paired criterion) in epidemiological investigations. examples illustrating the use of these methods are presented and their advantages in comparison with commonly used methods are shown.	2012	3434046
staff turnover as a function of performance in a public residential facility.	the relationship between employee turnover and performance was measured for 144 leavers and 144 stayers across 32 positions in a large institution for mentally retarded people. performance ratings for employees leaving the organization were significantly lower than for those who stayed. these performance differences occurred most significantly with involuntary dismissals and among direct-care technicians who comprise a major part of the institution's work force. the overall results suggest that ...	2012	3434588
dyadic peer interactions of mildly delayed and nonhandicapped preschool children.	mildly developmentally delayed and nonhandicapped 3- and 4-year-old children were paired systematically in a series of dyadic play sessions to evaluate the effects of companion status on important aspects of peer-related social and play behavior. mildly delayed children were paired with younger nonhandicapped children matched in terms of developmental level, with nonhandicapped children matched in terms of ca, and with other mildly delayed companions. mixed-age and same-age pairings for the nonh ...	2012	3434589
anaesthetic management for carbon dioxide laser surgery in tracheobronchial lesions.	there are technical difficulties associated with anaesthesia in patients who undergo laser surgery to the trachea and main bronchi using the carbon dioxide laser. an anaesthetic technique using spontaneous ventilation is described which has been used successfully in 33 patients.	2012	3434745
study of ileostomy in dogs, functional aspects, optic and scanning electronic microscopy.	containing ileostomy has been a permanent aim of researchers. different technics for containing in the ileal derivations has been proposed, very little filled the requisites, but no one reached the desired aim, and the problem continues unsolved. the authors, based in experimental study in two groups of dogs submitted to ileostomy, with and without preservation of ileal pylorus, observed the following parameters: weight dog clinical evaluation of animals (diarrhea, infection of surgical wound an ...	1986	3435265
heterologous protection in murine cutaneous leishmaniasis.	mice immunized with a glycolipid antigen (gl) of leishmania major plus adjuvant are relatively resistant to subsequent infection with this protozoan parasite. the gl is affinity purified on the monoclonal antibody wic-79.3 which is l. major-specific and does not react with l. donovani. when another monoclonal, wic-108.3, which cross-reacts with several leishmania species, is used to affinity purify gl from l. donovani, the eluted material can partially protect genetically resistant mice against ...	1987	3436638
[diagnosis of bladder cancer by cytogenetic method].		2005	3437647
[diagnosis of bladder cancer by cytogenetic method].		2005	3437647