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in vitro susceptibility of dermatophytes from munich to griseofulvin, miconazole and ketoconazole.various recent clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum from munich were subjected to antimicrobial susceptibility testing using the microdilution method. both azoles miconazole and ketoconazole were found to be more active than griseofulvin. comparatively high inhibitory concentrations of griseofulvin were especially found with tr. mentagrophytes. on the whole miconazole turned out to be even somewhat more effective th ...19902359418
fungi causing dermatophytosis in lagos, nigeria.dermatophytes of the genera trichophyton, microsporum and epidermophyton were isolated from 162 (41%) of 395 patients with clinical manifestations of ringworm infection reporting at the lagos university teaching hospital, lagos, nigeria between january 1986 and december 1987. of the 162 strains of fungi isolated, 120 (74.1%) were microsporum species and 7 (4.3%) were epidermophyton floccosum. superficial mycosis was most prevalent on the skin (59.3%), followed by that of the hairs (27.2%). infec ...19902364899
[dermatophyte infections caused by microsporum canis and microsporum audouinii in the greifswald area].report of serial diseases of dermatophytoses caused by m. canis (5 patients) and m. audouinii (9 patients). two cats and a dog were the infective source of m. canis-infection. m. audouinii-infection was stated in a children ward; here the infective source had not been detected. remarkable are the identical morphological lesions of tinea capitis resp. corporis and the affections of adults in the two groups of patients. griseofulvin therapy and additional veterinary hygienical treatment in case of ...19902365106
[dermatomycoses observed at the dermatologic clinic, pavia university. 2) pathology of microsporum gypseum].microsporum gypseum infections are 0.4% of 4900 suspected dermatomycoses examined with direct microscopic exam and culture on lactrimel medium or d.t.m. this geophilic dermatophyte was isolated in 20 cases (1.5% of all dermatophytes). more frequently m. gypseum caused tinea corporis (13 cases: 65%) and rarely tinea capitis (2 cases: 10%), tinea faciei (2 cases), tinea manus (2 cases) and tinea cruris (1 case). both sexes are equally affected. direct microscopic exam was negative in 2 cases. this ...19902365400
[tinea capitis in adults. description of 3 cases]. 19902365401
differentiation of medically important isolates of bipolaris and exserohilum with exoantigens.soluble culture extracts of bipolaris australiensis, b. hawaiiensis, b. spicifera, exserohilum longirostratum, e. mcginnisii, e. rostratum, and helminthosporium solani were used to prepare reference antisera in new zealand white rabbits. the absorbed reference antisera were tested by a microimmunodiffusion method against concentrated culture filtrates prepared from 115 environmental and clinical isolates of alternaria spp., bipolaris spp., curvularia spp., dactylaria sp., drechslera spp., embell ...19902380387
the value of electrophoretic protein patterns for the study of microsporum canis.whole-cell protein analysis of clinical isolates of microsporum canis by polyacrylamide gel electrophoresis (page) showed small but inconsistent differences in protein patterns. all clinical isolates closely resembled the (-) mating type of arthroderma otae. a reference strain of a. otae (+) mating type from japan gave a page pattern which was distinct from those of the clinical isolates. mating studies showed that the progeny of these reference (+) and (-) mating types had a variety of distinct ...19902380880
[the clinico-laboratory evaluation of the efficacy of the external treatment of microsporosis using a 5% mebetizol ointment].therapeutic efficacy of external application of 5 percent mebetizol ointment was analyzed in the treatment of 140 patients with microsporosis. the best effect was achieved when such therapy was combined with oral griseofulvin in glabrous skin microsporosis. the effect of treatment of mycosis of the hairy part of the head was less marked. no cases of the therapy intolerance, complications, or recurrences were recorded. toxic effects of mebetizol on vital organs were not observed. external applica ...19902389613
[isolation and identification of dermatophytes]. 19902400536
identification and serotyping of microsporum canis isolates by monoclonal antibodies.hybridoma cells were produced by fusing mouse myeloma cells with spleen cells from mice primed with an exoantigen of microsporum canis. three clones produced antibodies which were examined by the western blot technique for their potential usefulness in the identification of m. canis isolates and differentiation of strains within the species. based on reactions with immunological determinants, all of the m. canis isolates tested presented either species- or strain-specific domains. monoclonal ant ...19862420823
serotyping of fungal isolates by precipitating monoclonal antibodies.ascites fluid from hybridoma cell lines producing monoclonal antibodies to an exoantigen of microsporum canis was assayed for its precipitating properties. three types of monoclonal antibodies were used for serological analysis of heterologous mycelial cultures. based on specific antigenic determinants, the fungal strains showed different immunodiffusion reactivity within the species. the monoclonal antibodies also proved to be effective reagents for serotyping heterogeneous species. they may al ...19862425261
keratinolytic and keratinophilic fungi of children's sandpits in the city of turin.soils rich in keratinic residues constitute a permanent or occasional reservoir for dermatophytes and keratinolytic and keratinophilic fungi, and are a source of potential infection for man and animals. the keratinolytic and keratinophilic mycoflora of 28 sandpits in turin was studied to evaluate the risk of fungal skin infections that is run by children as they play in public parks and to lay the ground-work for a next epidemiological study of soil- and animal-inhabiting dermatophytes found in ...19862429185
incidence of keratinophilic fungi in rice-field soils.soil samples from rice-fields, collected at monthly intervals, were analysed by baiting technique for the incidence of keratinophilic fungi. nine species, among a total of 102 species isolated by various methods, were keratinophilic species (8.8%). these were recorded from 38 out of 45 samples collected. the distribution pattern of the different keratinophilic fungi and their significance are discussed.19872436049
taxonomic study of keratinophilic fungi isolated from soil and some mammals in france.in france, most of the researches have showed the distribution of dermatophytes and other keratinophilic fungi in the soil and in the coat of wild mammals. during these last years, we have also practiced numerous investigations about the distribution of such fungi. the isolated species are: trichophyton mentagrophytes, trichophyton terrestre, trichophyton ajelloï, trichophyton simii, microsporum gypseum, microsporum cookei, microsporum nanum, microsporum persicolor, anixiopsis stercoraria, chrys ...19882454405
supravital microscopic fluorescent technique for the detection of tinea capitis.a simple one-step, office technique for the identification of superficial mycoses is presented. buffered acridine orange is used as a supravital stain for direct examination of specimens under a fluorescence microscope. neither prior treatment with potassium hydroxide, nor tissue fixation is required. results usually can be obtained in less than five minutes. extensive training in use of the microscope is not required.19882458213
keratinophilic fungi isolated from children's sandpits in the nablus area, west bank of jordan.the keratinophilic fungi of 29 sandpits from kindergarten schools and public parks in the city of nablus was analysed to evaluate their role in the epidemiology of diseases caused by these fungi. seventy two species were recovered 28 of which were common to both kindergartens and public parks sandpits. high percentage (57.4%) of fungal isolates found had been identified as the causes of various types of mycoses. eight species of dermatophytes and closely related fungi were recovered, of which th ...19882461513
the hair follicle mites (demodex spp.). could they be vectors of pathogenic microorganisms?the hair follicle mites demodex folliculorum and d. brevis are the most common permanent ectoparasites of man. ordinarily they are harmless to their human host and appear to be of no medical significance. we present, however, an unusual finding regarding this mite, namely, that in a potassium hydroxide mount of a skin scraping from a mycotic plaque we found numerous demodex mites containing inside them spores of microsporum canis. this could mean that the putatively inoffensive demodex has the p ...19882467494
fungi in two swimming pools in assiut town, egypt.50 water samples from 2 public swimming pools were tested for the presence of fungi using the hair baiting technique and plate count methods. sabouraud's-dextrose agar and littman-oxgall agar media were used for isolation of the fungi. of the keratinolytic fungi 8 species were recorded of which three species were dermatophytes (trichophyton terrestre, 14% of the samples; t. mentagrophytes, 10% and microsporum gypseum, 6%). on littman-oxgall agar the following species were recovered: aspergillus ...19892475993
hair perforation by keratinophilic fungi.the in vitro hair perforation test as described by ajello and george, was applied to eight species of chrysosporium and one species each of microsporum and trichophyton. six of them were found to perforate hair while four were negative. chr. keratinophilum, m. gypseum and tr. vanbreuseghemii were able to perforate and degrade hair rapidly. the micromorphological changes were also described.19892477700
fungi on the claws of buffalo and cow in egypt.the frequency of occurrence of fungi in 120 claw samples of buffalo and cow from different localities at assiut governorate was determined. thirty-seven species which belong to twenty genera were collected from the two substrates and the most common genera were chrysosporium (eleven species of chrysosporium were isolated). aspergillus and scopulariopsis. from the preceding genera chrysosporium sulfureum was common on cow claws but c. merdarium was slightly dominant on buffalo claws than on cow c ...19892482351
[in vitro study of the antifungal activity of two chlorine derivatives to be used in antisepsis].the activity of two chlorine derivates, sodium hypochlorite in water solution with nacl (product a) and electrolytic chloroxidant (product b) has been tested in vitro against potentially human pathogenic fungi (aspergillus niger, aspergillus fumigatus, microsporum gypseum, candida albicans, cryptococcus neoformans, trichophyton mentagrophytes, microsporum canis, epidermophyton floccosum, trichophyton rubrum, sporotrix schenkii). for a. niger, the relation of the two compounds has also been consi ...19892483652
[isolation of microsporum ferrugineum in cuba. presentation of a case].a mycologic study of skin lesions in a patient with tines corporia was made. a fungus with a strong yellow stain color was isolated and classified as microsporum ferrugineum, a species isolated in our country for the first time.19892486225
studies on antifungal agents: aromatic acid hydrazones of o. vanillin, o. veratraldehyde, 5-bromo-o. vanillin and bourbonal. 19892486268
isolation of human pathogenic fungi from barbers' shop of chhindwara (mp): a preliminary study.isolation of human pathogenic fungi was made from the barbers' shops of chhindwara. trichophyton mentagrophytes showed highest percentage of occurrence (30%), followed by trichophyton rubrum (26%) and aspergillus fumigatus (18%) whereas, the lowest relative density was exhibited by aspergillus niger and a hyphomycetous fungus (2%).19892486270
[dermatophytes in clinically healthy dogs and cats].the hair and skin of 300 clinically healthy animals, 268 dogs and 32 cats, were examined mycologically. the method described by mariat and tapia (1966) was used for the examination, along with square pieces of the fitted carpet kovral. the dermatophytes were isolated in 12 samples, all from the material taken from dogs. trichophyton mentagrophytes was isolated six times, microsporum canis four times, trichophyton gallinae once, trichophyton rubrum once. the origin of the dermatophyte trichophyto ...19892494787
[infections which humans in the household transmit to dogs and cats].an overview of the most important infections which can be transmitted from humans to pet dogs and cats is presented. two quite different sources of infection stand diametrically opposite each other: 1. the transmission of active human infections to dogs and cats and 2. the transmission of infectious agents by feeding raw meat, offal, unsterilized milk products, kitchen scraps and contaminated feedstuffs. humans can be the source of the following infections: 1. zoonoses with reciprocal modes of t ...19892500809
faeriefungin: a new broad-spectrum antibiotic from streptomyces griseus var. autotrophicus.faeriefungin, a polyol polyene macrolide lactone antibiotic, was isolated from the mycelium of streptomyces griseus var. autotrophicus, msu-32058/atcc 53668, collected from the soil sample of a fairy ring in an old lawn in lansing, michigan. faeriefungin has some properties similar to the previously reported polyene macrolides, mycoticin and flavofungin, but possesses different physiochemical and biological properties. aspergillus, fusarium, microsporum, trichophyton, and alternaria spp. were co ...19892509636
ketoconazole-resistant mutants of microsporum gypseum. i. isolation of mutants, biochemical methods.the ketoconazole-resistant mutants were isolated from four strains of the dermatophyte microsporum gypseum. the frequency of spontaneous mutants ranged within 10(-8) to 10(-9) (per spore and nucleus). the method was established for obtaining the spontaneous mutants manifested as the faster growing sectors. by means of mutagenic effect of uv radiation, the frequency of mutants increased by one order. the method used for determination of ergosterol the biosynthesis of which could be associated wit ...19892530847
ketoconazole-resistant mutants of microsporum gypseum. ii. characteristics of mutants.the presented study deals with the properties of two wild strains of dermatophyte microsporum gypseum and of eleven mutants resistant to ketoconazole. the growth rate of spontaneous mutants is greater than that of the wild strain, the group of uv-induced mutants manifests in general lower growth rate. the resistance level varies in the interval 1.1-1.6 (spontaneous mutants), resp. 2.7-5.5 (uv-induced mutants). the phenomenon of cross-resistance to other imidazole drugs (miconazole, clotrimazole) ...19892530848
[ecology, epidemiology and clinical symptomatology of microsporum gypseum infections].microsporum gypseum is a geophilic fungus with a world-wide distribution, which is considered to be involved in keratin degradation in the soil. since 1977, mycotic skin infections due to m. gypseum have been repeatedly observed in the department of dermatology in graz, austria. a predominance of females was evident. as a rare event, m. gypseum has also been cultivated from onychomycotic lesions.19892531287
adaptation of microsporum gypseum to ketoconazole.the mycelium of the strain mg-155 of the dermatophyte microsporum gypseum was repeatedly cultivated in three subinhibitory concentrations of ketoconazole: 1, 2, and 6 micrograms/ml. the adaptability of the fungus to this antifungal drug was estimated on the basis of the sensitivity of spores and the sensitivity of the mycelium. in the first phase, the mycelium grew on the medium with ketoconazole in consequence to the physiological adaptation (without the change of genome). in the following phas ...19892533842
further studies on the influence of dibutyryl camp, theophylline and prostaglandin e1 on composition and biosynthesis of phospholipids in microsporum gypseum.exogenous supplementation of dibutyryl camp and camp modulators like theophylline and prostaglandin e1 in the growth medium of microsporum gypseum lead to increase in the levels of phosphatidylcholine and lysophosphatidylcholine and thereby in total phospholipid content. these observations were further confirmed by the increased incorporation of [32p]orthophosphoric acid into total phospholipid and [14c]choline into phosphatidylcholine and lysophosphatidylcholine. the activity of sn-glycerol-3-p ...19892561114
the in-vitro antifungal spectrum of itraconazole.the activity of itraconazole on 6113 fungal strains belonging to 252 species was evaluated in fluid media. the test medium was brain heart infusion broth for all fungi, except for pityrosporum ovale, for which it was dixon broth. most of the human and animal pathogens and a large number of saprophytes were highly sensitive: dermatophytes, candida, cryptococcus, torulopsis, pityrosporum, aspergillus, penicillium, sporothrix, dimorphic fungi, phaeohyphomycetes, agents of eufungal mycetoma, entomop ...19892561189
tinea capitis caused by microsporum praecox in a patient with sickle cell anaemia.microsporum praecox rivalier ex padhye, ajello et mcginnis is the validated name for the taxon originally published as sabouraudites praecox rivalier. we describe here the first case of small-conidial, ectothrix type hair invasion caused by m. praecox in an adult woman from oklahoma, u.s.a., suffering from sickle cell anaemia. this fungus is now being encountered with greater frequency as an etiologic agent of ringworm infection.19892600736
keratinophilic fungi associated with rabbit claws in egypt.using the soil plate technique, thirty one species appertaining to twenty three genera were recovered from 160 samples of rabbit claws which were collected from a rabbit farm at assiut. of the true keratinophilic fungi chrysosporium tropicum was the most prevalent where it colonized 56.25% of the samples. microsporum gypseum was rarely isolated in this study. among the non-keratinophilic fungi penicillium funiculosum. p. jenseni and paccilomyces lilacinus were of low incidence (20%, 19.37% and 1 ...19892600778
fungal kerion--total scalp involvement due to microsporum canis infection.we report the case of a 5-year-old girl who developed a remarkably extensive kerion of the scalp due to microsporum canis infection. total scalp involvement of this severity and prolonged duration is now unusual, but there has been surprisingly little residual cicatricial alopecia. microsporum canis does not respond well to ketoconazole, and griseofulvin remains the drug of choice for dermatophyte infections involving hair; a prolonged course may be necessary. this case also demonstrates the ben ...19892605809
additive effect of the combination of griseofulvin and ketoconazole against microsporum canis in vitro.the susceptibility of 28 strains of microsporum canis to griseofulvin, to ketoconazole and to a combination of both antifungal drugs was determined. griseofulvin proved to be more active than ketoconazole. the combination of both antifungal agents was found to exert an additive effect.19892608097
fungitoxic studies on bark extract of lawsonia inermis against ringworm fungi.during screening of barks of 30 plants species against microsporum gypseum and trichophyton mentagrophytes, only lawsonia inermis exhibited absolute toxicity. the lawsonia bark extract was found to possess fungistatic nature at its maximum inhibitory dilution of 1:30 (w/v) against both the test pathogens but, become fungicidal at 1:10 (w/v). the extract showed broad fungitoxic spectrum when tested against 13 ring worm fungi. further the fungitoxicity of the extract remained unaltered at high tem ...19892613539
keratinophilic fungi of animal and bird pens in egypt.samples were collected from 44 pens under animals and birds for the estimation of keratinophilic fungi using the hair-baiting technique. thirty-nine species which belong to eighteen genera were recovered. chrysosporium, aspergillus, and penicillium were the most frequent genera. from keratinophilic fungi, myceliophthora anamorph of corynascus sepedonium, myceliophthora anamorph of corynascus novoguinensis, microsporum boullardii, m. gypseum, trichophyton metagrophytes and arthroderma sp. were re ...19892614672
isolation of keratinophilic fungi from the dust of ferry boats and trains in italy.the occurrence of fungi of the genera epidermophyton, microsporum, trichophyton and chrysosporium in dust collected from 10 ferry boats and 11 railway cars in italy was studied. ferry boats: 101 colonies of fungi were isolated. of the dermatophytes, e. floccosum represented 2.0% of all the colonies isolated, m. canis 3.0%, m. gypseum 5.0% and tr. mentagrophytes represented 2.0%. e. floccosum was isolated from 2 ferry boats, m. canis from 3, m. gypseum from 4 and tr. mentagrophytes from 2. only t ...19892615785
electron microscopy of microsporum cookei after 'in vitro' treatment with protoanemonin: a combined sem and tem study.the ranunculaceous derivative protoanemonin (pra) was studied as an antifungal agent on the dermatophyte microsporum cookei. the ultrastructural changes that pra brought about in this fungus were observed with both the transmission and scanning electron microscopes. the main anomalies noted were abnormally shaped hyphae and within the cytoplasm, multimembranous bodies which were irregular in shape and size, and tubules of 25 and 60 nm in diameters. mitochondria, nuclei and vacuoles were also var ...19892615800
frequency of dermatophytes causing tinea corporis in tripoli, libya. 19892617593
[evaluation of the efficacy of a new antimycotic molecule for topical use: naftifine].the antifungal efficacy and tolerability of naftifine (cream, gel, 1% solution), were tested in an open, mycologically controlled study in 29 patients (mean age 32.7 +/- 2.8 years; 15 males, 14 females) with dermatomycosis caused by dermatophytes and yeasts. particularly, 16 patients were affected with tinea corporis; 11 patients by pityriasis versicolor and 2 other by cutaneous candidiasis. the mean treatment period was 32.9 days in a range from 1 to 44 days. only one patient, with cutaneous ca ...19892620916
dermatophytes and keratinophilic fungi in cats and dogs.during an 11 month period from january to november 1987, dermatophytes and keratinophilic fungi were isolated from 70 (75%) of 93 cats and 62 (36.9%) of 168 dogs. the most common isolate was microsporum canis from 54 (58%) cats and 33 (19.6%) dogs, followed by trichophyton mentagrophytes from 5 (5.4%) cats and 9 (5.3%) dogs, aphanoascus fulvescens (4 cats and 9 dogs), m. gypseum (5 dogs), tr. terrestre (3 dogs) myceliophthora vellerea (2 dogs) and chrysosporium indicum, chr. merdarium and chr. t ...19892622475
isolation of dysgonic strains of microsporum canis in bilbao (spain).in this report, we describe five cases of dermatophytosis caused by dysgonic strains of microsporum canis which occurred in the area of bilbao (spain). the clinical presentations and responses to treatment of these infections were apparently similar to those caused by typical strains of this species but the increasing prevalence of dysgonic and other atypical strains of m. canis and the relative stability of the dysgonic morphology are the important features shown in our study. contact with anim ...19892628559
dermatophyte fungi in the guinea savannah region of nigeria and the changing phase of dermatophytosis in nigeria.approximately 8,000 patients with various skin diseases were seen at the ahmadu bello university teaching hospital, kaduna, nigeria between january 1983 and december 1986. 174 (2.2%) presented with features in which a clinical diagnosis of superficial fungal infection was made or suspected. 69 out of 190 (36.3%) of specimens taken from skin lesions or nails from these patients were mycologically positive. the fungi isolated were trichophyton rubrum (24.6%), tr. soudanense (13.0%), candida albica ...19892677715
[action of sulconazole on candida and dermatophyte antigens]. 19892688525
[action of 2 new imidazole derivatives (butoconazole and sulconazole) on candida, trichophyton and aspergillus]. 19892688526
animal models for dermatomycotic infections. 19892688913
[antifungal effects in vitro of jasmon and some similar compounds. structure-activity relationship].the antimycotic activity in vitro of jasmon and 6 closely related substances has been tested against four different dermatophytes, candida albicans, pityrosporum ovale and aspergillus fumigatus. jasmon had the highest activity. among the other substances tested only thiazolidines with a carbonyl function developed antifungal properties against dermatophytes. 2,4 thiazolidinedione at 450 ppm inhibits the growth of trichophyton rubrum.19892699545
[synthesis and antifungal activity of n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-alpha-substituted -1-(4-substi tuted) naphthalenemethanamines].thirty (e)- or (z)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-alpha-subst itu ted-1-(4-substituted)naphthalenemethanamines were synthesized for searching of more potent and less toxic antimycotic agents. all title compounds and most of the intermediates are new. results of preliminary biological tests showed that most of the title compounds exhibited activity against the common pathogenic fungi such as cryptococcus neoformnas, candida albicans, aspergillus fumigatus, cladosporium carrionii, sporo ...19892700413
keratinolytic fungi of wadi qena in egypt.forty-six soil samples collected from different sites of wadi qena were examined for keratinophilic fungi using the hair baiting technique. thirty-two species in addition to one variety of each of a. nidulans and a. flavus which belong to eighteen genera were recovered. aspergillus, chrysosporium, penicillium, microsporum and fusarium were the most frequent genera developed from baited soils.19892707686
[microsporum canis infection in rabbits and its transmission to humans].the infection of the capillitium of an 8-year old child due to microsporum canis is described. the child occasionally visited its mother working at an animal farm. the focus of the infection was found in farm rabbits infected by m. canis. a contamination of the environment (cages and floors) by the above mentioned dermatophyte could also be demonstrated. the infection was transferred to an animal feeder as well. the infection focus was eliminated by strict disinfection and sanitary measures. the ...19892710160
tinea capitis caused by microsporum canis in an adult.the authors report a case of tinea capitis in a woman aged 49, with a previous history of discoid lupus erythematosus. the pathogenic agent was microsporum canis. the patient was cured after two months therapy with griseofulvin and local antimycotics.19892710161
fungal ribosomal vaccines. ii. dermatophyte vaccine--initial studies on the antigenicity of a crude ribosomal fraction from microsporum canis.a crude ribosomal fraction was extracted from microsporum canis. the ratio of spectrophotometric readings at 260 and 280 nm was 1.56 and the nucleic acid to protein ratio of the fraction was 1.5. a delayed intradermal hypersensitivity test in guinea pigs was positive and dose related.19892739692
a contribution to the study of tinea capitis in lusaka, zambia.a study of tinea capitis in urban and rural schools of lusaka revealed two dermatophytes, vis., microsporum langeroni and trichophyton violaceum as the causative agents of tinea capitis among school children. tinea capitis was more common among boys (18.0%) than girls (14.7%), with prevalence of 16.8% and a peak infection at 9-11 years for both sexes. clinically, most cases due to both m. langeroni and t. violaceum were non-inflammatory. the inflammatory cases were caused by t. violaceum. the hi ...19892743909
microsporum canis with polymorphous macroconidia.an atypical strain of microsporum canis was isolated in our laboratory, which was characterized by a variety of polymorphous macroconidia. these are demonstrated by illustrations. based on our observation and literature, the relationship between microsporum canis and microsporum distortum is discussed. epidemiologic aspects are mentioned.19892747740
a study of tinea capitis in sri lanka.between january 1978 and december 1987, 106 cases of tinea capitis were detected in sri lanka. diagnosis was confirmed mycologically by microscopic examination and by culture. tinea capitis accounted for 3.4% of all superficial fungal infections seen during this period. this figure is low when compared with the incidence of this disease reported in other countries. five main types of clinical manifestation were encountered. inflammatory lesions were observed in 50% of the patients. eighty-five p ...19892754578
clinical examinations with chinofungin spray and chinofungin powder.tolnaftate is effective in the local treatment of dermatophyte infections. it is recommended primarily in infections caused by trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum, microsporum canis and malassezia furfur. it may be useful as an adjuvant local therapy in chronic dermatophyte infections treated with griseofulvin.19892756514
keratinophilic fungi isolated from antarctic soil.in the present study, 10 soil samples were collected aseptically from an equal number of areas of the antarctic in the zone occupied by the 1986-1987 italian expedition for research on keratinophilic fungi. of particular interest was the isolation of a pathogenic fungus, microsporum gypseum, from two sites in the base camp occupied by men and by skuas. trichophyton terrestre was isolated from a site in which people worked and through which penguins and skuas passed. the most widespread fungal sp ...19892770838
isolation of keratinophilic fungi from floor dust in arab elementary and preparatory schools in the west bank of jordan.floor dust collected from classrooms of thirty three elementary schools (16 for girls, and 17 for boys) (children aged 6-11), and twenty four preparatory schools (13 for girls, and 11 for boys) (children aged 12-14) was studied for the occurrence of keratinophilic fungi with respect to human presence and age of children. tichophyton mentagrophytes was present in 15.4% of the preparatory schools for girls, in 12.5% of elementary schools for girls, and in 11.8% of elementary schools for boys. it w ...19892770839
fungus invasion of human hair tissue in tinea capitis caused by microsporum canis: light and electron microscopic study.previously, we reported a morphological change of trichophyton violaceum in hair tissue in black dot ringworm. to investigate the morphology of microsporum canis in human hais tissue, three cases of tinea capitis by m. canis were examined by both light and electron microscopy. the fungal elements, which were located deeplyin the keratogenous zone, showed nonseptate hyphae in the outer part of the hair cortex. with the upward development of hair tissues, some hyphae invaded the keratinized inner ...19892774655
influence of supplementation of saturated alkanes on the membrane properties of microsporum gypseum.microsporum gypseum cells grown on saturated alkanes of different chain lengths (c10, c12, c14, c16 and c18) exhibited increased levels of total phospholipids and sterols. a significant increase in the content of phosphatidylcholine was observed in alkane-grown cells. increased saturation of phospholipid fatty acid was observed with all the alkanes studied, which was mainly due to the decreased amount of c18:1 and c18:2 with concomitant increase in the levels of palmitic acid. the affinity for g ...19892777326
foot infections due to hendersonula toruloidea and scytalidium hyalinum in coal miners.a total of 250 coal miners were screened for mycotic skin infections. sixty-six (34.8%) miners had clinical lesions on their feet which proved to be of mycotic etiology by direct microscopy and culture. hendersonula toruloidea, the commonest etiological agent, was the sole agent recovered from 23 (34.8%) of the positive cases and was also isolated from three (4.5%) cases of mixed infection with dermatophytes (two cases with trichophyton rubrum and one with trichophyton mentagrophytes var. mentag ...19892778576
keratinophilic fungi of school playgrounds in the nablus area, west bank of jordan.the distribution of keratinophilic fungi in the soil of 57 school playgrounds in the nablus area was studied with relation to human presence. a total number of 73 species was recovered. thirteen of these species were dermatophytes and closely related fungi. the most common and frequent species of the latter fungi were: arthroderma cuniculi (found in 32.1% of school playgrounds), chrysosporium keratinophilum (32.1%), microsporum gypseum (10.7%), t. terrestre (7.1%), and c. asperatum (7.1%). twent ...19892797112
keratinophilic fungi on sheep hairs from the west bank of jordan.the mycoflora of the hair in 285 sheep from the west bank of jordan was analysed and the frequency of occurrence and the relative importance value for different fungal species found were calculated. ninety six species which belong to 36 genera were isolated. forty one of these species were either well-known agents of animal and human mycoses (trichophyton verrucosum, t. mentagrophytes, microsporum nanum, m. canis, and others), or have been isolated from human and animal lesions (arthroderma cuni ...19892797114
[in vitro action spectrum of a new antifungal agent derived from morpholine: amorolfin].the minimal inhibitory concentrations of amorolfin against yeasts, dermatophytes, sporothrix schenckii and moduls were determined on sabouraud's dextrose agar by dilution test procedure (dixon's agar for malassezia). the yeasts (candida, torulopsis, trichosporon) present various susceptibility, mic ranged from 0.01 to 1 micrograms/ml-1 for sensible strains particularly malassezia (0.005-0.5 microgram/ml-1) ranged from 20 to 100 micrograms/ml-1 for resistant isolates. amorolfine is also effective ...19892797885
[in vitro antifungal spectrum of ciclopiroxolamine].the ciclopiroxolamine is a new synthetic antifungal agent related to pyridones; it is the ethanolamine salt of the pyridone acid 6-cyclohexyl 1-hydroxy 4-methyl 2 (1h). the antifungal properties of this molecule was tested in vitro against pathogenic species such as yeasts. (candida, torulopsis, malassezia), moulds (aspergillus, scopulariopsis) and dermatophytes, (microsporum, trichophyton, epidermophyton) using an agar dilution method (sabouraud or dixon). the results seem to be remarkably homo ...19892797886
optimization of protoplast formation, regeneration, and viability in microsporum gypseum.factors affecting high yields, regeneration frequencies, and viability of protoplasts from clonal cultures of microsporum gypseum were investigated. maximum yields of protoplasts were obtained after 6 hrs digestion of 2-4 days old mycelium with novozyme 234 using cacl2 (0.4 m) as an osmotic stabilizer and glycine + hcl (ph 4.5) as the buffer system. mercaptoethanol + dithiothreitol (0.01 m) proved to be the best pretreatment of mycelium prior to digestion with enzyme. a regeneration frequency of ...19892811981
effect of dibutyryl cyclic amp on lipid synthesis in microsporum gypseum.the influence of intracellular levels of camp on the lipid synthesis of microsporum gypseum has been examined by exogenous supplementation of dibutyryl camp and its activators/inhibitors. incorporation of [14c]acetate into various lipid fractions of m. gypseum was markedly enhanced in the presence of dibutyryl camp and its modulators, probably as a consequence of increased intracellular camp levels, which, in turn, affected the lipid biosynthesis. increased activities of phosphatidic acid phosph ...19882838092
nosocomial infections with microsporum canis. 19872883230
dermatophytosis in institutions for the elderly. 19892910391
isolation and identification of the principal siderophore of the dermatophyte microsporum gypseum.the dermatophyte microsporum gypseum has been shown to produce two siderophores under conditions of low-iron stress. these compounds have been separated as fe(iii) complexes on silica gel, and the principal siderophore has been identified as ferricrocin using the methods of amino acid analysis, comparative thin-layer chromatography, partial sequencing by gas chromatography-mass spectrometry, ultraviolet spectroscopy, and proton nuclear magnetic resonance spectroscopy of the al(iii) complex.19862938628
dermatophytosis. a review of diagnosis and current therapy.inhibition of fungal growth and accelerated keratolysis are the necessary ingredients of dermatophyte therapy. often, the primary fungus is destroyed by secondary bacterial invasion or the body's immune response. clinicians must recognize this possibility and, in such instances, treat the bacterial infection or immune response rather than the suspected dermatophyte.19862943391
[isolation of microsporum persicolor from skin lesions and river bottom sediments]. 19862948219
cystine metabolism in the dermatophyte microsporum gypseum. ii. utilization of cystine in media containing peptides and proteins. 19852949518
[role of the m. canis carrier state of healthy animals in the epidemiology of zoonotic microsporum infection]. 19872956788
15-year survey of tinea faciei in the adult.in a series of 100 adults with tinea faciei various dermatologic manifestations were mimicked, viz.: discoid lupus erythematosus in 52 patients, lymphocytic infiltration in 15, seborrheic dermatitis in 11, rosacea in 8, contacts dermatitis in 7, polymorphous light eruption in 4 and granuloma faciale in 3. trichophyton rubrum was isolated in 78% of the respective cases, other isolated organisms being microsporum canis (13 cases), trichophyton violaceum in 6, trichophyton mentagrophytes (asteroide ...19882971583
genetic basis of virulence in dermatophytes. 19882977473
tinea capitis. current concepts. 19883048214
in vitro interactions between blastomyces dermatitidis and other zoopathogenic fungi.the results of in vitro interactions between colonies of blastomyces dermatitidis and six other zoopathogenic fungi are reported. the interactions were found to range from neutral with histoplasma capsulatum and candida albicans to strongly antagonistic with microsporum gypseum, pseudallescheria boydii, and sporothrix schenckii, and including lysis by cryptococcus neoformans. these observations suggest that interactions between zoopathogenic fungi may be one of the biotic factors likely to influ ...19883058276
[etiology of dermatomycoses in the lódź region]. 19883065829
effect of choline, ethanolamine and serine supplementation on the membrane properties of microsporum gypseum.phospholipid bases, choline and ethanolamine, when supplemented in the growth medium of microsporum gypseum resulted in an increase in the corresponding phospholipid and total phospholipid content. however, when serine was supplemented, marginal changes were observed. the fatty acid profile of phospholipids remained almost unchanged. the uptake of lysine, leucine and aspartic acid in the spheroplasts of choline- and ethanolamine-grown cells was higher as compared to the control. 1-anilinonaphath ...19873114585
tinea capitis caused by microsporum nanum. 19873127143
[antifungigram of dermatophytes].the sensitivity of microsporum gypseum to five antifungal agents was carried out by the disk diffusion method. the influence of the culture medium composition and physiological state of the microorganism was studied. the differed setting of antifungal disks enabled a comparative study of their action on spores and mycelium. best results were obtained on a complex medium (casitone) using spores as inoculum. the sensitivity of microsporum canis, m. gypseum and trichophyton interdigital to the five ...19883140848
susceptibility of microsporum and trichophyton species to suicide inhibitors of polyamine biosynthesis.dfmo (difluoromethylornithine) and dfma (difluoromethylarginine), irreversible suicide inhibitors of ornithine and arginine decarboxylase activities (odc and adc) respectively, inhibit the growth of six species of microsporum and six species of trichophyton. trichophyton species in general, are more sensitive than microsporum species. dfma inhibits growth as effectively as dfmo but at a 10-fold lower concentration. inhibition is specific, as a number of substrates and end products of odc and adc ...19883145970
cystine metabolism in the dermatophyte microsporum gypseum. i. utilization of cystine in media containing glucose. 19853161292
studies on antifungal agents. 23. novel substituted 3,5-diphenyl-3-(1h-imidazol-1-ylmethyl)- 2-alkylisoxazolidine derivatives.the synthesis and antifungal activity of a novel series of substituted 3,5-diphenyl-3-(1h-imidazol-1-ylmethyl)-2-alkylisoxazolidine derivatives (15-30) are described. the synthesis of the title compounds was accomplished via a 1,3-dipolar cycloaddition reaction of alpha-substituted ketonitrones with appropriate styrene precursors. the compounds when tested in vitro in solid agar cultures exerted a very potent antifungal activity against a wide variety of yeast and systemic mycoses and dermatophy ...19883172137
mycological studies on zoophilic dermatophyte isolates of finish and swedish origin. 19883173419
[epidemiology of tinea of the scalp in togo].in 1985, 374 children of primary schools in north and south togo were examined and sample of hair were collected on all children with small sterile squares of carpet. 11% of the children in the north (dry and urban area) and 20% in the south (wet and rural area) had obvious clinical lesions. two species of dermatophytes were isolated: microsporum langeronii and trichophyton soudanense; this second dermatophyte being uncommon in the south. moreover, 15% of the children of the north and 42% of the ...19883180319
further in vitro studies with oxiconazole nitrate.oxiconazole nitrate was compared in vitro with ketoconazole and econazole nitrate in tests with 96 dermatophytes, 18 isolates of malassezia furfur, and seven isolates of exophiala werneckii. an agar dilution procedure was used employing either kimmig's agar or sabouraud's dextrose agar supplemented with olive oil and tween 80. econazole was the more active compound in tests with microsporum species (41 isolates) and most isolates of trichophyton species (45 isolates). oxiconazole was the more ac ...19883180708
[microsporum infection]. 19883181463
dermatophyte-hormone relationships: characterization of progesterone-binding specificity and growth inhibition in the genera trichophyton and microsporum.we reported previously that trichophyton mentagrophytes contains a cytoplasmic macromolecule which specifically binds progesterone. progesterone is also an effective inhibitor of growth of the fungus. we report here studies which characterize more fully the specific binding properties and the functional responses of t. mentagrophytes and taxonomically related fungi to a series of mammalian steroid hormones. scatchard analysis of [3h]progesterone binding in both the + and - mating types of arthro ...19883182998
activities of compound g2 isolated from alfalfa roots against dermatophytes.an antimycotic agent, compound g2, isolated from alfalfa roots exhibited considerable activity against the six most common dermatophytes. mics in agar and broth dilutions ranged from 10 to 30 micrograms/ml and from 2 to 10 micrograms/ml, respectively. g2 was fungicidal at 5 to 22 micrograms/ml. structure and toxicity relations are discussed.19883190186
some unusual periorbital dermatoses.three case reports of primary periorbital dermatitis are presented. the etiology of these were molluscum contagiosum, microsporum canis, and coccidioides immitis. in each case, the presenting complaint was unusual since the primary lesion started in the periorbital region.19883207312
[growth and survival of various pathogenic dermatophytes in bottom sediment and sewer sludge]. 19883212358
keratinophilic fungi on the hair of cows, donkeys, rabbits, cats, and dogs from the west bank of jordan.the mycoflora of hair of 111 cows, donkeys, rabbits, cats, and dogs were analysed and the frequency of occurrence and the relative importance value of the different fungal species isolated were calculated. total numbers of species 56, 45, 48, 23, and 11 were recovered from cows, donkeys, rabbits, cats, and dogs respectively. the majority of the keratinophilic fungi isolated were either well-known mycotic agents or have been recovered from various animal and human lesions. these comprised 87.8%, ...19883221913
dermatophytes that infect animals and humans.there are many occupations that expose people to dermatophytes. infections from dermatophytes may be transmitted from animal to animal, animal to human, human to human, and human to animal in a cyclic fashion. the most common species of dermatophytes that infect animals and humans, microsporum and trichophyton, are discussed here.19883234032
[microsporum praecox: apropos of 4 cases]. 19883239908
[treatment of patients with zooanthroponotic microsporosis with griseofulvin in combination with alpha-tocopherol]. 19883245301
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