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[the gingiva of the marmoset. (callithrix jacchus)]. 20034957601
chromosome analysis of four species of marmosets (callithrix jacchus, tamarinus mystax, tamarinus nigricollis, cebuella pygmaea). 19664959871
studies on experimental bacteremia and pyelonephritis in the marmoset (callithrix jacchus). 19684972244
[an unrestricted marmoset (callithrix jacchus) perceives pictures]. 19684972844
chorionic gonadotropin excretion during pregnancy in the marmoset, callithrix jacchus. 19694977682
histopathology of experimentally induced nutritional deficiency cheilosis in the marmoset (callithrix jacchus). 19694980011
the meibomian glands of the marmoset (callithrix jacchus). 19694986924
quantitative studies on scent marking in the marmoset (callithrix jacchus). 19704988037
dental development in the cotton ear marmoset (callithrix jacchus). 20164988192
[toxoplasmosis in nonhuman primates. ii. attempts at experimental infection in macacca mulata, cebus apella and callithrix jacchus; and search for antibodies in several species of platyrrhinus]. 19715002530
[on the presence of acid phosphatase in the pyloric glands of the marmoset (callithrix jacchus)]. 20005236327
[hybridism between callithrix jacchus (l., 1758) x c. geoffroyi (humboldt, 1812) (callithricidae, primates)]. 19705521414
trichospirura leptostoma gen. et sp. n. (nematoda: thelazioidea) from the pancreatic ducts of the white-eared marmoset callithrix jacchus. 19675624881
effects of fibre on digestibility and passage time in callithricidae.the effects of fibre in a pelleted diet on food intake, digestibility of crude fibre, dry matter and energy, on passage time and consistency of faeces were studied in 2 species of callithricidae, callithrix jacchus and saguinus fuscicollis. coarse cellulose, microcellulose, wheat bran and shrimp meal (chitin = crude fibre) were tested in diets containing 2,4 and 6% total crude fibre, respectively. digestibility and passage time were determined by inclusion of 0.5% cr2o3 in the diet. both cellulo ...19846087023
ovulation in the marmoset monkey: endocrinology, prediction and detection.circulating progesterone, oestrogens and lh were measured in female marmosets (callithrix jacchus) over the periovulatory period. progesterone concentrations increased in all animals within 1 day of the estimated day of ovulation, confirming the usefulness of this hormone for retrospective detection of ovulation. oestradiol-17 beta and lh both showed a preovulatory rise, but due to the large quantity of plasma required (oestradiol: 0.2 ml) and the length of time taken for the assay (lh: 2-3 days ...19846090570
infectious mononucleosis-like response in common marmosets infected with epstein-barr virus.callithrix jacchus marmosets infected with epstein-barr virus (ebv) with or without concurrent treatment with cyclosporin a (cysa) remained healthy. five marmosets given virus alone developed lymphocytosis and heterophile antibody. antibody to ebv capsid antigens (vca) appeared and remained at titers of 1:40-1:80 from 15 weeks onward. two animals produced antibody to the r component of early antigens (ea) from six weeks onward. five cysa-treated ebv-infected marmosets showed no increase in total ...19846094675
presence of ph2-sensitive circulating interferon among callithrix jacchus marmosets.significant and relatively stable levels of serum-interferon were demonstrated in a callithrix jacchus population. this circulating interferon was acid-sensitive in all cases, classifying it as immune or "gamma-type" interferon. our results in these hematopoietic chimeras suggest that the presence of immune-type or at least ph 2-sensitive interferon could be related to the presence of two allogenic lymphocyte populations in each marmoset.19846094815
a new approach to the role of noradrenaline in learning: problem-solving in the marmoset after alpha-noradrenergic receptor blockade.nine marmosets (callithrix jacchus) were tested on a variety of visual discrimination learning tasks in a wisconsin general test apparatus with or without alpha-noradrenergic receptor blockade achieved by the administration of aceperone. after aceperone, animals were found to be severely and consistently impaired at learning the first task of each test session and to be impaired on new and repeated reversal learning. they were, however, unimpaired on learning another similar task in each test se ...19816114497
junin virus infection of calithrix jacchus: haematological findings.haematological changes produced by experimental junin virus infection of a platyrrhine monkey, callithrix jacchus were studied. normocytic and normochromic anaemia appeared after 7 days post infection (p. i.), and increased steadily until day 21 p. i. reticulocytes and circulating erythroblasts were elevated during the anaemia, reached a peak on day 7 p. i., and disappeared later. platelets and leukocytes showed a significant decrease from days 14 and 18 p. i., respectively. these alterations co ...19826127935
transplacental and direct exposure of mouse and marmoset to ethylnitrosourea: analysis of chromosome aberrations.the effect of ethylnitrosourea (enu) on chromosomes of mouse bone marrow cells and transplacentally exposed embryonic liver cells was investigated. chromosome aberrations were found to be dose- and time-dependent. the maximum damage was seen 6 h after the exposure. chromosome aberrations were also induced in bone marrow cells and lymphocytes of marmosets (callithrix jacchus) directly exposed to enu. aberrations did not, however, occur in offspring whose mothers were treated with enu before conce ...19836137079
nasal and intrathalamic inoculations of primates with tacaribe virus: protection against argentine hemorrhagic fever and absence of neurovirulence.callithrix jacchus marmosets were inoculated by different routes with two stocks of tacaribe virus, one from suckling mouse brain and another from human diploid mrc5 cells. all 12 primates inoculated by nasal route developed neutralizing serum antibodies without any clinical signs. all 6 primates receiving the mouse brain-tacaribe virus were protected against lethal challenge with pathogenic xj strain of junin virus, while protection was also conferred in 4 out of 6 primates receiving the diploi ...19846148851
the vaccine potential of cell surface glycoproteins from trypanosoma cruzi.an experimental trypanosoma cruzi 90 kda cell surface glycoprotein (gp90) vaccine, previously shown to be protective in mice is similarly effective in marmosets (callithrix jacchus jacchus). protection in the mouse is completely dependent on the adjuvant saponin and immunological studies confirm that gp90 is intrisically poorly immunogenic. both specific antibody and cell mediated immunity are potentiated strongly by saponin and the resulting protective immunity is long lasting (six months). it ...19846151689
the postnatal development of the temporomandibular joint of the common marmoset (callithrix jacchus).the temporomandibular joints (tmj) of 55 male and 50 female common marmosets (callithrix jacchus) with an age range of 1 day- to < 12-yr-old have been studied to extend the knowledge on the craniomandibular articulation of this primate. details of changes in the bone structure, gross and functional anatomy, and histologic appearance of the marmoset tmj during the neonatal period, infancy, childhood, adolescence, and adulthood are compared with those which occur in the tmj of man. it is concluded ...19826153018
demonstration of ocular dominance columns in a new world primate by means of monocular deprivation.we investigated the pattern transneuronally transported [3h]proline to the visual cortex of normal and deprived marmosets (callithrix jacchus). in the normal marmoset a continuous band of label was evident within layer iv of striate cortex. following injection of the closed eye of deprived marmosets, distinct fluctuations of label were apparent over the base of layer iv in both hemispheres. these results support the hypothesis that the presence of ocular separation of geniculo-striate afferents ...19816162527
syncytium-forming virus of common marmosets (callithrix jacchus jacchus).this communication describes the isolation and characterization of a new syncytium-forming virus of common marmosets (callithrix jacchus jacchus). the virus, isolated from skin explants and peripheral leukocytes of healthy animals, induced syncytia and subsequent cytolysis of several human, simian, and rodent fibroblastic cultures and induced a carrier state in mixed fibroblastic-epithelial or epithelial cell lines. cytoplasmic and nuclear viral antigen was demonstrated in infected cells by indi ...19816164648
organophosphate poisoning in marmosets.due to faulty use of a chlorpyriphos-diazinon combination as a pesticide within a laboratory animal house, 19 marmosets of 2 species (saguinus fuscicollis and callithrix jacchus) of 98 at risk died from organophosphorous poisoning (19%) mortality). the clinical signs were those of cholinesterase inhibitors. the morphological lesions consisted predominantly of haemorrhages in several organs, particularly the cns, and of bone marrow necroses.19826176756
skin reaction in callithrix jacchus penicillata to phytohemagglutinin.sixty marmosets (callithrix jacchus penicillata) were intradermally tested with phytohemagglutinin. it was possible to classify this population into three groups on the basis of the reactions: 1. negatives, 2. those which showed just local hemorrhage, and finally 3. a group which developed a wheal as well as hemorrhage. the biopsy at the site of the reaction demonstrated several microscopic foci. this finding contrasted with the homogeneous cellular infiltration found in the human controls.19826187198
inhibition of renin in the primate callithrix jacchus (common marmoset).the effects of an antiserum against human kidney renin and of h-142, a peptide inhibitor of human renin, were studied in the primate callithrix jacchus (common marmoset). in severely volume-depleted (low-salt diet and repetitive injections of furosemide), conscious marmosets, the antiserum reduced blood pressure to the same extent as the converting enzyme inhibitor teprotide (-31 +/- 7 sem mmhg and -30 +/- 5 mmhg). in mildly volume-depleted (normal salt diet and single injection of furosemide), ...19836196144
alteration of blood coagulation and complement system in neotropical primates infected with junin virus.the neotropical primate callithrix jacchus infected with junin virus presented an acute disease with hematological and neurological manifestations and died 17 to 24 days after infection. this picture is similar to that of human argentine hemorrhagic fever (ahf). blood coagulation and complement studies were performed in ten c jacchus animals inoculated with 10(3) tcid50 of junin virus, the prototype pathogenic xj strain. four monkeys were used as normal controls. infected monkeys and normal cont ...19836197506
blood pressure effects of renin inhibition by human renin antiserum in normotensive marmosets.the effects on blood pressure of an antiserum against pure human kidney renin were studied in conscious and anesthetized (pentobarbital, 24 mg x kg-1 i.p.) small new world monkeys (common marmosets). the antiserum inhibited the enzymatic activity of renin by 50% in a dilution of 1:45,000 in marmoset and 1:50,000 in human plasma. the antiserum (0.2 ml i.v.) decreased blood pressure in conscious marmosets on normal sodium intake by 15 +/- 5 (sd) mmhg and after salt depletion by 31 +/- 13 mmhg. a c ...19846199985
binding of human lymphocyte-specific monoclonal antibodies to common marmoset lymphoid cells.commercially available monoclonal antibodies which bind to human lymphocyte subsets were screened for their ability to bind to lymphoid cells from the common marmoset callithrix jacchus. anti-leu-5 and t11 were the only pan t-cell antibodies which reacted strongly. none of the antibodies which bind human lymphocytes of the helper/inducer subpopulation reacted with c. jacchus cells and only one antibody, t8, specific for the cytotoxic/suppressor subset, bound to the marmoset cells. the two antibo ...19846200238
rapid regression of fetal adrenal zone and absence of adrenal reticular zone in the marmoset.developmental changes in plasma dehydropiandrosterone (dha) and in adrenal histology were studied in several marmoset species (callithrix jacchus and saguinus labiatus, nigricollis, and fuscicollis) to evaluate these primates as experimental models for the study of fetal adrenal zone regression. newborn marmosets had a prominent fetal adrenal zone, plasma dha levels above 1000 ng/dl, and plasma dha sulfate (dhas) levels of 140 micrograms/dl. the fetal zone regressed dramatically during the first ...19826216097
further consideration of the learning impairment after aceperone in the marmoset: effects of the drug on shape and colour discrimination and on an alternation task.ten marmosets (callithrix jacchus) learned to discriminate between pairs of small grey objects differing only in shape or small plain plaques differing only in colour, in a wisconsin general test apparatus. each day, each animal was presented with three consecutive visual discrimination problems in the order shape-colour-shape or colour-shape-colour. after aceperone, an alpha-noradrenergic antagonist, animals were impaired at learning the first but not the subsequent tasks of each trio. these re ...19836222386
an investigation of the effects of intracerebral injection in the marmoset of cytopathic cerebrospinal fluid from patients with schizophrenia or neurological disease.in experiments designed to investigate transmission, cerebrospinal fluid (csf) from patients with schizophrenia and neurological disease (huntington's chorea and multiple sclerosis) which had been found to induce cytopathic effects in human embryonic fibroblast cell culture was injected intracerebrally into mice, hamsters and marmosets (small new world primates). no evidence was obtained of transmission to mice or hamsters. a total of 15 marmosets (callithrix jacchus) was injected intracerebrall ...19836226054
hepatitis a and b: serologic survey of human and nonhuman primate sera.sera of humans and seven species of nonhuman primates were tested by radioimmunoassay and enzyme immunoassay for the presence of hepatitis a antibody, hepatitis b surface antigen and antibody to hepatitis b surface antigen. the outcome of testing a total of 276 serum or plasma specimens was as follows: with the exception of squirrel monkeys (0%) and cotton-top marmosets (0%), a considerable percentage of all other species tested had detectable antibodies to hepatitis a virus: humans 45.9%, chimp ...19806253744
[infection of new world primates by junin virus. ii callithrix jacchus]. 19806253762
herpesvirus saimiri: protective effect of attenuated strain against lymphoma induction.an attenuated strain of herpesvirus saimiri (a-hvs) induced a persistent, latent infection in common marmosets. virus was recovered from circulating lymphocytes of infected animals and antibody response to virus-specified antigens was demonstrated over 3-12 months pi. a-hvs-infected common marmosets and animals without previous a-hvs exposure were challenged with oncogenic hvs (125-825 pfu); marmosets without a-hvs infection developed malignant lymphoproliferative disease and died 3 weeks pi whe ...19806265382
natural antibodies to ebv-vca antigens in common marmosets (callithrix jacchus) and response after ebv inoculation.healthy common marmosets from two separate colonies, one in england and one in france, were found to have antibodies cross-reacting with epstein-barr virus structural antigens (ebv-vca). all seropositive animals were at least 2 years old. experimental ebv infection of marmosets of different ages led to seroconversion of inoculated weanlings. adult animals either developed antibody for the first time or showed an increase in their existing titers. both control and infected animals developed a pro ...19806265400
cross-protection in nonhuman primates against argentine hemorrhagic fever.the susceptibility of the marmoset callithrix jacchus to tacaribe virus infection was investigated to perform cross-protection studies between junin and tacaribe viruses. five marmosets inoculated with tacaribe virus failed to show any signs of disease, any alterations in erythrocyte, leukocyte, reticulocyte, and platelet counts or any changes in hematocrit or hemoglobin values. no tacaribe virus could be recovered from blood at any time postinfection. anti-tacaribe neutralizing antibodies appea ...19826276301
acute gastric dilatation in common marmosets (callithrix jacchus). 19816281555
poxvirus infection in a colony of common marmosets (callithrix jacchus).an epizootic poxvirus infection occurred in a colony of 80 common marmosets (callithrix jacchus) recently introduced to a laboratory facility. over an 18-week period, 29 of the monkeys exhibited skin lesions that persisted for 4-6 weeks. although eight marmosets died during the outbreak, their deaths were not attributed directly to the poxvirus infection. the skin lesions developed over the entire body surface including the soles and palms. initially characterized as erythematous papules, they q ...19826281571
analysis of dr-like molecules on a marmoset epstein-barr virus-induced cell line using a monomorphic anti-human hla-dr monoclonal antibody.mouse anti-hla d region-related (dr) monoclonal antibodies have been found to cross-react with peripheral blood leukocytes from one primate species, the common marmoset (callithrix jacchus). immunoprecipitates of radioactively labeled cells extracted from a marmoset epstein-barr virus-induced cell line were analyzed by one- and two-dimensional gel electrophoresis and compared with the dr antigens of a human lymphoblastoid b cell line. two chains of estimated molecular weights of 34 000 (alpha) a ...19826284521
junin virus infection of callithrix jacchus: pathologic features.infection of callithrix jacchus, a new world primate, with the prototype strain of junin virus produced a severe disease. the animals developed multifocal hemorrhages and characteristic microscopic lesions such as meningoencephalitis, interstitial pneumonia, lymphocytic depletion of lymphatic tissue, hepatocytic necrosis, and a variable decrease in bone marrow cellularity. high virus concentrations correlated with lesions, and with the presence of viral antigenic determinants as revealed by immu ...19836301303
fatal lymphoproliferative disease in a common marmoset (callithrix jacchus) following inoculation of ag876 strain of epstein-barr virus and a tumor-promoting agent: preliminary report.we report here the development of a fatal lymphoproliferative disease in a common marmoset (callithrix jacchus) following inoculation of the ag876 strain of epstein-barr virus (ebv) and of the tumor promoting agent 12-o-tetradecanoylphorbol-13-acetate (tpa). the marmoset showed antibodies against ebv capsid and early antigens (vca, ea) but not against nuclear antigen (ebna). ebna was detected in impression smears from lymph nodes and liver, and the presence of the ebv genome was detected from th ...19836303683
respiratory disease associated with parainfluenza type i (sendai) virus in a colony of marmosets (callithrix jacchus).an outbreak of acute respiratory disease was observed in a colony of marmosets (callithrix jacchus). parainfluenza type i (sendai) virus was isolated from the lungs and from throat swabs of 2 animals which showed clinical signs of disease. a rising titre of serum neutralizing antibody to the virus isolated was detected in several affected animals. approximately 50% of the colony showed clinical signs of disease, and 3 animals died. the duration of illness ranged from 3 to 16 days.19836306336
the structure and epididymal maturation of the spermatozoon of the common marmoset (callithrix jacchus).maturation of the spermatozoon of the common marmoset (callithrix jacchus) during epididymal transit was investigated using light and electron microscopy. except for the caudal migration of the cytoplasmic droplet there were no apparent ultrastructural modifications, although interesting morphological features of the sperm head were observed such as the substructure of the acrosome and a waist at the equatorial region. alteration to the plasmalemma during maturation was reflected by an increasin ...19846325376
hematologic and immunologic responses in common marmosets (callithrix jacchus) infected with plasmodium knowlesi and epstein-barr virus.the hematologic and immunologic responses to infection with either the epstein-barr virus alone or infection with epstein-barr virus and plasmodium knowlesi were studied using common marmosets (callithrix jacchus). the assays performed included complete blood cell counts, determinations of natural killer cell activity, and determinations of antibody titers to epstein-barr virus early antigen, virus capsid antigen and the nuclear antigen. while no animal showed signs of lymphoproliferative diseas ...19846328114
the second, intralaminar thalamo-cortical projection system.in the marmoset (callithrix jacchus), hrp and 3h-apo-hrp were injected into various cortical regions and the positions of labelled neurons in the non-specific, intralaminar thalamic nuclei (n. centralis and centre m edian ) were investigated. although neuron populations projecting to the different cortical regions overlap widely, a coarse topology exists inasmuch as intralaminar neurons projecting to the posterior cortex were located more rostrally and those projecting to the anterior cortex wer ...19846331230
levels of circulating and urinary oestrogens during pregnancy in the marmoset monkey (callithrix jacchus).the levels of immunoreactive oestrone, oestradiol-17 beta and oestriol in plasma and urine were measured during early, mid- and late pregnancy in the marmoset monkey. in plasma, unconjugated oestrone remained less than 2% of total (conjugated plus unconjugated) oestrone throughout gestation, whereas unconjugated oestradiol-17 beta increased from 3% of the total value in early and mid-pregnancy to 35% in late pregnancy. the reversal in the unconjugated oestrone: oestradiol-17 beta concentration r ...19836401813
sex steroids and their relationship to binding proteins in the serum of the marmoset monkey (callithrix jacchus).a sex hormone binding globulin (shbg) similar to human shbg was identified in marmoset serum based on its gel electrophoretic mobility, isoelectric point and steroid binding properties. levels of serum shbg were measured in immature and mature males, immature females and females during the luteal phase and pregnancy; serum progesterone, 5 alpha-dihydrotestosterone (5 alpha-dht), testosterone, oestradiol-17 beta and oestrone were also measured. mean (+/- s.e.m.) concentrations of shbg in immature ...19836403644
plasma testosterone response to hcg stimulation in the male marmoset monkey (callithrix jacchus jacchus).in adult animals the intramuscular injection of hcg was followed by a rapid rise in plasma testosterone levels within 2-3 h and at doses of 40 and 80 i.u. hcg this primary response was followed by a second peak of testosterone at 48 h. prepubertal marmosets also responded to hcg stimulation with a rapid increase in plasma testosterone levels within 3 h, but the magnitude of this peak was lower than that observed in adult animals and no biphasic pattern was observed. in adult and prepubertal anim ...19836403699
placental transfer of hexachlorophene (hcp) in the marmoset monkey (callithrix jacchus).autoradiography was used to study the distribution of 2,2'-14c-methylene-bis-(3,4,6-trichlorophenol) (hcp) in pregnant marmoset monkeys in early (day 30-50) and late (around day 120) gestation and in a newborn (11 days old) pup. radioactivity was present in the conceptus at all stages of gestation, although the foetal concentration was lower than the maternal. in the embryo an accumulation was observed in the neural tube and in the embryonic membranes. in the late foetus and newborn monkey the h ...19836408890
relationship between ovarian and placental steroid production during early pregnancy in the marmoset monkey (callithrix jacchus).concentrations of progesterone, 17 alpha-hydroxyprogesterone, oestrone and oestradiol-17 beta in peripheral and utero-ovarian vein blood were measured during the first 60 days of pregnancy. the same hormones were also measured in peripheral blood samples from non-fertile cycles. peripheral levels of 17 alpha-hydroxyprogesterone, oestrone and oestradiol increased gradually during early pregnancy whereas concentrations of progesterone declined. the patterns of secretion of progesterone, 17 alpha-h ...19836415278
timing of ovulation and implantation in the common marmoset, callithrix jacchus, by monitoring of estrogens and 6 beta-hydroxypregnanolone in urine.urinary estrogen and 6 beta-hydroxypregnanolone excretions have been determined in female marmosets by means of hptlc. the levels observed in cycling females during implantation and abortion are reported. hormone analysis revealed a characteristic pattern showing cyclic fluctuations of estrogens and progesterone. estrogen metabolites increase during the follicular phase up to 1 microgram/ml, the progesterone metabolite level rises to 1.2 micrograms/ml urine during the luteal phase. maximum value ...19836416225
isolation, characterization and comparative aspects of the major serum apolipoproteins, b-100 and ai, in the common marmoset, callithrix jacchus.the two major apolipoproteins of marmoset serum have been isolated and characterized, and on the basis of physicochemical and immunological criteria are homologous with the human ai and b-100 proteins. marmoset apolipoprotein ai was the principal protein of high-density lipoproteins (hdl) and was purified by gel filtration chromatography and electrophoresis in alkaline-urea polyacrylamide gel followed by electrophoretic elution. purified marmoset apolipoprotein ai displayed an mr of approx. 2700 ...19836418212
stabilities of some constituents of marmoset (callithrix jacchus) plasma under various conditions of storage.the stability of various marmoset (callithrix jacchus) plasma constituents was investigated after storage at room temperature, 4 degrees c, and -20 degrees c. the method of sequential analysis ensured that the between-run bias of the methods of analysis used was drastically reduced, and the definitions of stability were linked to the imprecision of these methods. optimal conditions for storage for as long as 48 h depended on the analyte being measured. room temperature was optimal for cholineste ...19846418408
a comparison of tooth eruption patterns between two colonies of young marmosets (callithrix jacchus).the tooth eruption patterns of two large groups of young living marmosets were compared. the eruption sequence was essentially similar and was consistent with previous studies based on smaller numbers of dead animals. at nine mo, however, one group was more advanced than the other, although their craniofacial growth patterns were similar.19846420451
correlations among measures of playfulness and skillfulness in captive common marmosets (callithrix jacchus jacchus).infant sensorimotor and social skills, playfulness, and nonplayful behaviors were measured in common marmosets from 6 to 22 weeks old. different measures of skill showed a low concordance, implying that skill is a multiple rather than unitary attribute. significant correlations were found between the amount of social play infants performed from 11 to 13 weeks of age and their performance at 14 weeks in (1) competitive food tests with their mothers, and in (2) their ability to negotiate an obstac ...19846423428
body weight changes throughout pregnancy in the common marmoset callithrix jacchus.adult female common marmosets were weighed weekly for periods of 6-30 months. of 27 animals, 25 were pregnant at some stage of the investigation. patterns of body weight change throughout singleton, twin and triplet pregnancies were obtained and compared. maternal weight increase was dependent on the number of young in utero; however, little or no change in weight was observed during the first 13 weeks of gestation, irrespective of the number of offspring delivered subsequently. the overall mate ...19836423468
ultrastructural aspects of spermatogenesis in the common marmoset (callithrix jacchus).the pattern of normal spermatogenesis in the common marmoset, callithrix jacchus, is described and a system classifying the spermatogenic cycle into nine successive stages is presented. in contrast to most previous studies of spermatogenesis, the classification system developed in this study depends more upon the recognition of characteristic cell associations rather than upon identification of particular steps of spermatid development. the structurally simple acrosome of the marmoset spermatozo ...19846423594
genetic polymorphism and linkage of the sixth and seventh complement components (c6 and c7) in the common marmoset.using polyacrylamide gel isoelectric focusing and standard specific hemolytic detection methods, genetic polymorphisms have been found in the sixth and seventh complement components (c6 and c7) in two laboratory groups of common marmosets. the c6 locus is highly variable and the products of six alleles were observed; three c7 alleles were found. comprehensive breeding data indicated that both sets of alleles are inherited in an autosomal codominant manner. many of the c6 variants differed only b ...19846424644
follicular growth & induction of ovulation by gonadotrophins in the common marmoset callithrix jacchus. 19836425207
ovariectomy does not abolish proceptive behaviour cyclicity in the common marmoset (callithrix jacchus).unlike in other non-human primates, ovariectomy of the female marmoset did not alter heterosexual interactions. proceptive behaviour bouts retained the same cyclicity, duration and frequency within tests as during the ovarian cycle. significant rises in plasma levels of cortisol, progesterone, oestrone and testosterone were found during these proceptive behaviour bouts and in cortisol, progesterone and oestrone at their onset. results suggest a role for adrenocortical steroids in both maintainin ...19846425446
spontaneous neoplasms of the marmoset (callithrix jacchus). oral and nasopharyngeal squamous cell carcinomas.eight spontaneous highly invasive oral and nasopharyngeal squamous cell carcinomas were observed over an 18-month period in a breeding colony of the common marmoset (callithrix jacchus). affected marmosets were predominantly males over four years of age. the incidence of this tumor in the four-year-plus age group was 4.9%. the tumors were locally invasive through the palate to the nasal cavity, retrobulbar space and cranial cavity in some marmosets with lung metastases present in three cases.19846428027
a survey of the pathology of marmosets (callithrix jacchus) derived from a marmoset breeding unit.the results of a survey of the major pathological conditions encountered in an established breeding colony of common cotton-eared marmosets (callithrix jacchus) is presented. 265 home-bred and 70 imported wild-caught marmosets were examined. a heinz body haemolytic anaemia and skeletal muscle myopathy were the most common pathological findings and were considered to be a result of a complex nutritional deficiency involving vitamin e, selenium and protein. inflammatory disease of the intestinal t ...19836431178
craniofacial growth in young marmosets (callithrix jacchus).a cross-sectional study of craniofacial growth in young marmosets was performed. selected linear craniofacial measurements were obtained from groups of 5 animals of each sex at 3 monthly intervals from birth to 1 year. these data provide a baseline for comparison with other colonies and in the assessment of teratogens on craniofacial development.19836431179
an outbreak of bordetella bronchiseptica pneumonia in a colony of common marmosets (callithrix jacchus).an outbreak of bordetella bronchiseptica pneumonia occurred in a breeding colony of common marmosets (callithrix jacchus). 16 animals, all except one under 12 months of age, died suddenly. extensive lesions of pneumonia and pleurisy were found at necropsy and b. bronchiseptica was isolated from the nasopharynx, trachea and lungs. older animals had only a mild rhinitis. colonization of the nasal mucosa occurred in 71 of 156 marmosets.19836431182
canine tooth root infection as a cause of facial abscess in the common marmoset (callithrix jacchus).facial abscesses in a colony of common marmosets were found to be caused by abscessation of an upper canine tooth root. trauma to the upper canine, resulting in exposure of the pulp cavity, was thought to be the mode of infection. radiography was the most useful diagnostic aid in establishing the nature and extent of the lesion. antibiotic therapy alone was inadequate, and provision of drainage by extracting the tooth, in conjunction with antibiotics, proved the most effective treatment.19846431184
reference intervals for some clinical chemical parameters in the marmoset (callithrix jacchus): effect of age and sex.reference intervals for some clinical chemistry parameters in the marmoset were calculated. the effects of age (250-300 days compared with 500-550 days) and sex on the values found was investigated. alkaline phosphatase levels decreased with age, young males having higher plasma levels than young females, but no sex differences were discernible for older animals. levels of gamma-glutamyl transpeptidase and sorbitol dehydrogenase were higher in older males than in younger females. higher plasma i ...19846431185
the effect of haemolysis on some clinical chemistry parameters in the marmoset (callithrix jacchus).the effect of haemolysis on the levels of commonly analysed plasma constituents was investigated in the common marmoset. results were divided into a) low levels of extra haemolysis (less than 2 g/l plasma haemoglobin) and b) high levels of extra haemolysis (greater than 2 g/l plasma haemoglobin). mean changes in plasma constituent levels were examined and the correlation with increased haemolysis measured. large changes in malate dehydrogenase and lactate dehydrogenase were found at low levels o ...19846431186
morphological assessment of testicular maturity in marmosets (callithrix jacchus).the onset of spermatogenesis in relation to age, bodyweight and testes weight in 105 marmosets used in safety studies has been reviewed. the histological recognition of adverse effects on spermatogenesis is an important part of these studies and this survey indicates that male marmosets should be at least 50 weeks and preferably 60 weeks of age if an assessment of all stages of spermatogenesis is required for safety evaluation.19846431187
reproductive performance of three species of callitrichidae.the reproductive performance of three species of callitrichidae housed under identical conditions, including relatively spacious caging and visual screening, was compared. the three species were callithrix jacchus, saguinus fuscicollis, and saguinus oedipus. callithrix jacchus was the most reliable breeder, with the lowest percentage of stillborn and the highest post-weaning survival. while the reproductive performance of s oedipus was better than that generally reported for other colonies, the ...19846431191
serum biochemical, hematological and body measurement data for common marmosets (callithrix jacchus jacchus).blood samples were drawn and body measurements taken from healthy adult and juvenile common marmosets which had been housed under controlled environmental conditions for a minimum of 2 years. blood was analyzed for serum biochemical and hematological constituents.19846431192
an involvement of acetylcholine in object discrimination learning and memory in the marmoset.five marmosets (callithrix jacchus) were tested, using a wisconsin general test apparatus, on a series of junk object visual discrimination tasks, including new learning, 24-hr reversal and 24-hr retention. the effects of administering the cholinergic receptor blocking agent, scopolamine either just before or immediately after the new learning task, or just before the 24-hr reversal and retention tasks, were assessed. results suggest that scopolamine impairs new learning and impairs the encoding ...19846431311
reproductive status of adult daughters in family groups of common marmosets (callithrix jacchus jacchus).urine samples were collected from 6 pubertal female common marmosets at approximately 3-day intervals over a period of 3-7 months. all 6 females were the eldest daughters in their family groups. 3 of these females were subsequently removed from their families and sampled in isolation for another 2-3 months. levels of urinary pregnanediol-3 alpha-glucuronide were measured by radioimmunoassay in order to establish whether these females showed ovarian cyclicity. no cyclical fluctuations in the leve ...19846432658
undifferentiated carcinoma of the nasal tissues in the common marmoset.the occurrence of undifferentiated carcinoma of the nasal tissues in 3 adult marmosets is described. the tumours appeared to arise from the respiratory epithelium of the turbinate bones and nasal septum. they were poorly differentiated, invaded the paranasal sinuses and hard palate and metastasized to the lungs or liver.19846432862
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) (1-4 mg/kg i.p.) for 4 days induced dose-dependent parkinsonism in the common marmoset within 48 h. mptp produced profound akinesia, rigidity of the trunk and limbs, postural abnormalities, loss of vocalization and, in some cases, postural tremor. in a single animal the administration of l-dopa in conjunction with a peripheral decarboxylase inhibitor, reversed the parkinsonian symptoms. subsequent biochemical analysis show ...19846436758
cholinergic learning deficits in the marmoset produced by scopolamine and icv hemicholinium.common marmosets (callithrix jacchus) were trained to perform daily position discrimination learning tasks in a wisconsin general test apparatus. acetylcholine receptor blockade with scopolamine was found to impair position learning. testing on the day after scopolamine treatment suggested that a task learnt under scopolamine was not encoded into long term memory. acetylcholine depletion achieved by the intraventricular injection of hemicholinium 4 h before testing resulted in a profound impairm ...19846436862
organ and cellular distribution of inhaled metallic mercury in the rat and marmoset monkey (callithrix jacchus): influence of ethyl alcohol pretreatment.distribution of inhaled radioactive metallic mercury vapour (203hg0) in rats and marmoset monkeys (callithrix jacchus), with or without pretreatment by ethyl alcohol or aminotriazole (rat), was studied by means of whole-body autoradiography, microautoradiography and scintillation counting of excised organs. metallic mercury is oxidized by the catalase-h2o2 complex (complex i) to the ionic form (hg2+) and is known to be accumulated and retained in organs such as lungs, liver, myocardium, and brai ...19846437142
radiographic evaluation of appendicular skeletal maturation in the common marmoset (callithrix jacchus).the thoracic appendicular skeletal development of five common marmosets was monitored radiographically at weekly intervals from 1 day to 94 weeks of age and the times of appearance and fusion of 47 ossification centers were recorded. a range and average age for the appearance and fusion of each ossification center were calculated and compared to data available for the rhesus monkey and man.19836438328
a comparison of craniofacial growth between two colonies of marmosets (callithrix jacchus).general and craniofacial measurements from young marmosets in a recently established australian colony are presented and compared with similar data published for a long-established colony in the united kingdom. statistically significant differences between the colonies were those associated with large error variances, suggesting difficulties in locating certain landmarks rather than real differences in growth. thus, direct comparison can be made between craniofacial growth studies conducted at t ...19836438332
a survey of the pathology of marmosets (callithrix jacchus) under experiment.a survey of the pathology of 567 laboratory-bred cotton-eared marmosets (callithrix jacchus) is presented. there were few significant pathological changes in animals used in studies up to 6 months in duration, suggesting that the marmoset can be a useful non-human primate species for routine toxicology. the most common pathological changes encountered were chronic colitis, chronic thyroiditis and interstitial mononuclear infiltration in the kidney. no internal parasites were encountered, nor wer ...19846439947
diurnal and annual variations in plasma androgen levels in the adult male marmoset (callithrix jacchus).diurnal and annual variations in plasma androgen levels were studied in adult male marmosets. a distinct diurnal pattern, characterized by low androgen levels during the lights-on period and high levels during the lights-off period was observed (n = 7). in contrast to this, no definite circannual pattern in androgen levels was observed (n = 6).19846441783
x-ray-induced translocations in marmoset (callithrix jacchus) stem-cell spermatogonia.the induction of reciprocal translocations in spermatogonial stem cells of marmosets (callithrix jacchus) was studied after irradiation with different doses of x-rays (50, 100 and 200 rad) via spermatocyte analysis many cell generations later. the obtained results show a dose-effect relationship with clear saturation effects at 200 rad. the recorded frequencies of translocations were much lower than those reported for closely related marmosets (saguinus fuscicollis and saguinus oepidus). possibl ...19846504061
interhemispheric connections of visual cortex of owl monkeys (aotus trivirgatus), marmosets (callithrix jacchus), and galagos (galago crassicaudatus).interhemispheric connections of visual cortex were studied in owl monkeys, marmosets, and galagos after multiple injections of horseradish peroxidase into one cerebral hemisphere. areal patterns of connections were revealed in sections of cortex that was flattened and cut parallel to the surface. results were related to the locations of known visual areas, especially in owl monkeys, in which more visual areas have been established. the connection patterns in owl monkeys and marmosets are very si ...19846520237
investigations into the induction of chronic experimental arthritis in the common marmoset (callithrix jacchus).in an attempt to produce a superior model of rheumatoid arthritis, experiments have been performed to investigate the ease of induction of experimental arthritis in marmosets by immunological means. marmosets were sensitised with the following combinations of antigen and adjuvant: ovalbumin in freund's complete adjuvant (fca), ovalbumin in fca + bordetella pertussis, methylated-bsa in fca + b. pertussis or human fibrin in fca + b. pertussis, and subsequently injected with the corresponding antig ...19836622924
the effect of the ovarian cycle on the sexual behaviour of the common marmoset (callithrix jacchus).the sexual behaviour of 7 pairs of marmosets was observed during 30 minute tests for 44-68 days and blood samples were collected from females for measurement of plasma progesterone, testosterone and oestrone. copulations occurred throughout the ovarian cycle of 24-30 days. females used a "tongue-flicking" display both as an invitational behaviour (proceptive tongue-flicks) and during copulation (receptive tongue-flicks) most frequently during the peri-ovulatory period. frequencies of proceptivit ...19836683847
the myoglobin of primates: the night monkey, aotes trivirgatus (cebidae, platyrrhini, anthropoidea).the amino acid sequence of the myoglobin of the south american night monkey, aotes trivirgatus, is identical to that of the marmoset (callithrix jacchus [1]) except for residue 21 which is isoleucine in the marmoset, like in all other anthropoids, but valine in aotes. analysis of a possible pathway of the evolution of aotes myoglobin using 18 known primate myoglobin sequences [2-5] supports the classification of the night monkey within anthropoidea and platyrrhini but it indicates that this spec ...19846692912
a stereotaxic x-ray map of the hypothalamus of the marmoset monkey callithrix jacchus.precise hypothalamic surgery in the marmoset monkey callithrix jacchus cannot be performed by means of the horsley-clarke stereotaxic procedure. thus, a simple stereotaxic x-ray technique was developed. technical requirements are a stereotaxic frame for small animals and a dental x-ray source. a sagittal map shows hypothalamic structures in relation to surrounding bony landmarks. corresponding coronal plates allow target determination in that plane. intracerebral coordinates based on the positio ...19806766871
[reservoirs and wild vectors of trypanosoma cruzi. lxxv: natural t. cruzi infection of the monkey callithrix jacchus (linnaeus, 1758)]. 19806773112
[histoenzymologic data on the epithelial cells of the gastric mucosa of marmosets (callithrix jacchus & callithrix penicillata)].the gastric mucosa of marmosets is devoid of udpg-gt; phosphorylases; g-6-pa; f-1,6-pa; alanyl aminopeptidase and leucine aminopeptidase. only the acid phosphatase was seen with a stronger reactivity in the chief cells. the other enzymes (ldh; g-6-pdh; 6-pgdh; nadph2-tr; cis-aconitase; icdh; sdh; mdh; cytochrome oxidase; nadh2-tr; a-gpdh; b-ohbdh and nonspecific esterase) showed a stronger reactivity in the parietal cells.19806774386
regulation of oestrogen-induced lh release in male and female marmoset monkeys (callithrix jacchus).the positive-feedback action of oestradiol-17 beta on lh release was studied in gonadectomized male and female and intact male marmoset monkeys. positive feedback was observed in normal intact males in response to a single subcutaneous injection of 35 micrograms oestradiol benzoate. the sustained elevation in oestradiol-17 beta levels achieved by the injections resulted in a marked suppression of circulating testosterone concentrations. subcutaneous injections (0.5 mg/injection) of testosterone ...19806776280
a case of placenta praevia in a common marmoset (callithrix jacchus). 20066776678
cemented annulation as an age criterion in the common marmoset (callithrix jacchus).teeth from 18 marmosets, seven months to 5.8 years of age, were studied histologically. a minimum of one dark and one light band comprised one cemental annulation. age was estimated by counting the number of annulations and adding four months to premolar and eight months to canine teeth for tooth development. cemental annulations were most consistent near the gingival border on the labial aspect of the tooth. the method will be valuable in estimating the ages of marmosets and other nonhuman prim ...19806777495
influence of season on birth distribution in marmosets and tamarins.the cotton-topped tamarin in captivity exhibits a seasonal influence on birth distribution, while the captive silvery marmoset, common marmoset, goeldi's monkey and red-mantled tamarin are not significantly affected.19806780724
the maturation and aging of the vertebrae of marmosets.this study deals with the growth, maturation, and age changes to the cartilaginous end-plates of vertebrae from marmosets (callithrix jacchus) varying in age from birth to 10 years. the cartilaginous end-plate is divided into an inner growth layer and an outer articular zone that abuts against the intervertebral disc. the growth cartilage gradually narrows and disappears by 1 year of age, when the animal reaches physical maturity. the articular cartilage undergoes changes in collagen and ground ...20096781074
immunological characterization of hemopoietic cells in the common marmoset, rhesus monkey, and man. in search of a model for human marrow transplantation.bone marrow, lymphoid, and peripheral blood cells from the common marmoset and rhesus monkey have been tested with a panel of heterologous and monoclonal antibodies, and their reactivity pattern has been compared with that of blood and bone marrow cells from human donors. conventional antibodies reveal extensive cross-reactivity within the b cell, t cell, and granulocytic systems in all three species, however, some important differences have been exposed. only the monoclonal antibodies to hla-a, ...19816784292
supplemental feeding of marmoset (callithrix jacchus) triplets.in a colony of marmosets (callithrix jacchus), all fifteen infants from five sets of triplet births were successfully reared with their parents. two supplemental feedings were given each infant daily. as an alternative to hand-rearing or foster rearing, the supplemental feeding method eliminated the time-consuming process of hand caring for an infant on a 24-hour per day basis.19816787328
pharmacologic manipulations of brain catecholamines and the behavior of callithrix jacchus (marmoset).in experiment 1, groups of marmosets were injected with 50 - 200 mg/kg l-dopa, 0.5 - 2.0 mg/kg apomorphine (ap), or 0.5 - 5.0 mg/kg methamphetamine. the number of head movements, number of body movements, number of times the tongue was extended, and the time the animal remained in an upright posture were scored during a 90-min period after the injections. l-dopa and ap induced large dose-dependent increases in body movements and time in upright posture. furthermore, the smallest dose of ap induc ...19816787644
plasma prolactin concentrations during the ovarian cycle and lactation and their relationship to return of fertility post partum in the common marmoset (callithrix jacchus).a heterologous double-antibody radioimmunoassay was used to measure plasma prolactin concentrations in 27 marmosets. the assay was valid for the marmoset because plasma levels of prolactin were increased in response to trh and metoclopramide and suppressed in response to bromocriptine treatment. during the cycle there were no consistent changes in plasma prolactin concentrations. during lactation mothers suckling single or twin infants had higher prolactin levels than did non-suckling females an ...19816788944
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