Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| inappropriateness of the association of diphenhydramine with diethylcarbamazine for the treatment of lymphatic filariasis. | the efficacy of diphenhydramine, an antihistaminic, in preventing adverse reactions to diethylcarbamazine (dec) in patients infected with wuchereria bancrofti, was assessed by treating 50 patients with both drugs and 57 with dec alone. it was found to be ineffective, and to cause drowsiness in all those unaffected by adverse reactions. the authors conclude that the combined use of both drugs for the treatment of bancroftian filariasis, which is the usual practice in brazil, should be avoided. | 1989 | 2645415 |
| protective immunity in lymphatic filariasis. | 1989 | 2647512 | |
| fine structure and localization of anionic sites on the surface of microfilaria of wuchereria bancrofti. | the fine structure of the sheath and the cuticle of microfilaria of wuchereria bancrofti was analysed and the results obtained were compared with those from other filarial parasites. cationized ferritin particles bind to the surface of the sheath and the epicuticle. no binding of colloidal iron hydroxyde particles to the microfilaria surface was observed. reaction product indicative of carbohydrates containing vic-glycol groups was not observed in thin sections of microfilaria submitted to the p ... | 1989 | 2649230 |
| antibodies to phosphocholine-bearing antigens in lymphatic filariasis and changes following treatment with diethylcarbamazine. | sera from a total of 78 patients infected with wuchereria bancrofti or appropriate controls were assayed for anti-phosphocholine antibodies in an enzyme-linked immunosorbent-assay (elisa), using phosphocholine as an antigen. anti-pc antibodies (both igm and igg) were observed in patients with all clinical forms of filariasis but, unexpectedly, were not significantly different from those of normal controls. among the filariasis patients, however, individuals with patent microfilaraemia had signif ... | 1989 | 2649285 |
| pulmonary eosinophilic syndromes. | 1989 | 2650585 | |
| filariasis. the scourge of india. | 1989 | 2651338 | |
| annual transmission potential of bancroftian filariasis in an urban and a rural area of west bengal, india. | the annual transmission potential of wuchereria bancrofti was calculated from the number of infective larvae found in the number of culex quinquefasciatus expected to bite an individual exposed 24 hr a day for a year in calcutta and in a rural (memari) area. in calcutta, an average of 151 mosquitoes/night/person were collected; it was calculated that 55,028 mosquitoes could bite a person per year, including an average of 177 infective mosquitoes containing 319 infective larvae of w. bancrofti. a ... | 1989 | 2653062 |
| microfilaria of wuchereria bancrofti in fine-needle aspirate from a colloid goiter. | 1989 | 2656143 | |
| gravid adult female worms of wuchereria bancrofti in fine needle aspirates of soft tissue swellings. report of three cases. | gravid adult female worms of wuchereria bancrofti were observed in fine needle aspirates of soft tissue swellings from three patients. an inguinal lymph node was aspirated in two cases, and a breast nodule was the site of aspiration in the third case. in one of the inguinal lymph node aspirates, two adult gravid female worms were identified. | 1989 | 2658448 |
| adult filarial worm in fine needle aspirate of an epididymal nodule. | 1989 | 2658449 | |
| [a survey of filariasis in the comoro islands, in great comoro and mohéli]. | the filariasis of w. bancrofti with nocturnal periodicity is, together with malaria, the principal endemic disease in the comoros islands. well studied on mayotte island, which remained a french territorial collectivity, its prevalence and distribution are less known in the grand comoros, anjouan and moheli islands which form the federal islamic republic of the comoros. the study of the nocturnal microfilariae in the grand comoros and moheli in 1987 is the opportunity to assess the situation of ... | 1989 | 2663209 |
| differential recognition of two cloned brugia malayi antigens by antibody class. | the humoral and cellular immune response to filarial parasites is complex. numerous studies have shown that antibodies to a large number of protein and non-protein antigens may be produced over the course of infection and that immune recognition of any given antigen may vary by disease manifestation and by immunoglobulin class. we have used the techniques of molecular cloning to attempt to dissect this complex interaction, and describe here two clones, isolated from an expression library constru ... | 1989 | 2664506 |
| filarial parasites exhibit unusually high levels of choline acetyltransferase activity. | the presence of unusually high levels of choline acetyltransferase (chat, ec 2.3.1.6) in human and animal filarial parasites has been demonstrated. the levels of chat were highest in male worms of brugia malayi and brugia pahangi, with specific activities in crude extracts of about 2.27 and 1.26 mumol min-1 (mg protein)-1, respectively. the enzyme levels in these worms were over 10-20 times higher than in male worms of litomosoides carinii. the chat levels were about 2-5 times higher in male tha ... | 1989 | 2664508 |
| [epidemiological surveillance of filariasis after its being basically eradicated in shandong province]. | this paper reports the results of epidemiological surveillance in areas where filariasis has been basically eradicated and control measures no longer adopted in shandong province. a 3-year longitudinal surveillance in 18 villages in 5 counties and a cross-sectional survey in 13 villages of 4 counties were carried out. the results showed that the average microfilaria rate was further reduced from 0.28% and 0.15% in 1980 to 0.19% and 0.05% in 1986, decreased by 32.1% and 66.7% respectively. 34.2% ... | 1989 | 2670312 |
| filariases. | it is apparent that there are many similarities among the various filariae. besides a common life cycle, with an arthropod vector and human hosts, there are similarities in the diseases that they produce. this clinical picture takes one of two main courses: (1) characteristic disease produced by the presence of adult nematodes in their target tissue, which distinguishes typical cases for each of the filariae, and (2) the systemic hypersensitivity reactions to the circulating microfilaria, which ... | 1989 | 2670375 |
| effectiveness of spaced doses of diethylcarbamazine citrate for the control of bancroftian filariasis. | forty-seven wuchereria bancrofti microfilaria carriers were treated once weekly for 12 weeks with 6 mg/kg dec-c. microfilaria densities ranged from 1 to 101 mf/20 cmm (mfd-50 of 9.75 mf/20 cmm) before treatment. of 42 persons who completed treatment, 26 (62%) were microfilaria negative in 1-ml venous blood samples. microfilaria densities in the 16 patients that remained positive ranged from 1 to 50 mf/ml (mfd-50 of 2.59 mf/ml). weekly spaced doses of dec-c resulted in a significant reduction in ... | 1989 | 2672282 |
| filarial ascites associated with carcinoma of the pancreas. | 1989 | 2672794 | |
| prevalence of bancroftian filariasis & its control by single course of diethyl carbamazine in a rural area in tamil nadu. | the prevalence of microfilaraemia, clinical spectrum of bancroftian filariasis and vector potential were studied in vettavalam village in north arcot district of tamil nadu. the effectiveness of selective therapy with diethyl carbamazine (dec) in controlling filariasis in rural areas was also evaluated. the prevalence of microfilaraemia (mf rate) and disease (disease rate) was found to be 11.7 and 11.09 per cent respectively. hydrocele was the dominant clinical sign in males and lymphoedema in f ... | 1989 | 2674003 |
| bancroftian filariasis in tambol na-sai, amphoe li, lamphun province: a preliminary survey for microfilaraemia. | a preliminary survey for bancroftian filariasis in villagers of ban prabat heuy tom, tambol na-sai, amphoe li, lamphun province was performed between july 12, 1986 and march 19, 1987. a total of 1,435 villagers comprising 668 females and 767 males were examined for microfilaraemia in peripheral blood. microfilariae were found in five males of which two cases were found to have developed hydrocele at a lesser degree and all of them had formerly resided in an endemic area of tak province. microfil ... | 1989 | 2674319 |
| uptake and development of wuchereria bancrofti in culex quinquefasciatus that fed on haitian carriers with different microfilaria densities. | in studies conducted between 1984 and 1986, the vector competency of culex quinquefasciatus was assessed after bloodfeeding on 61 haitian volunteers with different densities of wuchereria bancrofti microfilariae (mf) and on 11 that were amicrofilaremic. infected volunteers included persons previously given diethylcarbamazine citrate for 12 consecutive days and some that were untreated. mosquitoes, derived from field-collected larvae, were released under bed nets and fed upon the volunteers while ... | 1989 | 2679171 |
| detection of a new focus of brugia malayi infection in orissa. | 526 people were surveyed in a village called chudamani, in balasore district of orissa, for detection of asymptomatic microfilaria (mf) carriers. of these 36 (6.8 per cent) were cases found to harbour mf; 19 cases had brugia malayi, 4 wuchereria bancrofti and 5 cases had mixed infection. in 8 cases, species could not be ascertained. for the first time after 1955, a focus of b. malayi has been detected in orissa. | 1989 | 2681391 |
| wb e34 monoclonal antibody: further characterization and diagnostic use in bancroftian filariasis. | the wb e34 monoclonal antibody raised against wuchereria bancrofti microfilarial excretory secretory (mf es) antigen was reported to be useful in detecting the filarial antigen in w. bancrofti and brugia malayi infected sera. further studies in this laboratory showed that this monoclonal antibody reacts with a stage-specific antigen of w. bancrofti filarial parasite. wb e34 identified three antigenic components with molecular weights, 55, 57.5, and 63 kilodaltons (kd) in western blot analysis. t ... | 1989 | 2681621 |
| tropical pulmonary eosinophilia: analysis of antifilarial antibody localized to the lung. | acute tropical pulmonary eosinophilia (tpe) is characterized by wheezing, pulmonary infiltrates, marked peripheral blood eosinophilia, and very high serum levels of filaria-specific antibodies. to evaluate the amount and character of the filaria-specific antibodies in the lungs in this disorder, bronchoalveolar lavage was carried out in individuals with acute tpe, in normal subjects, and in patients with elephantiasis or asthma. striking elevations of total ige were found in the lower respirator ... | 1989 | 2685125 |
| fractionation, characterization and diagnostic potential of filarial antigens isolated from hydrocoele fluid in bancroftian filariasis. | filarial antigen was isolated from hydrocoele fluid and fractionated on ultrogel aca 44. six protein fractions (hfa c1 to hfa c6) were chromatographically separated from the column. of the 4 antigenic fractions (hfa c1, hfa c2, hfa c3 and hfa c5), hfa c3 was a major reactive fraction with filarial serum immunoglobulin g. analysis of hfa c3 by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) yielded 18 bands of mr 18,000-160,000. two fractions, hfa c3-7 and hfa c3-9 of mr 48, ... | 1989 | 2690421 |
| bancroftian filariasis in pondicherry, south india: 1. pre-control epidemiological observations. | a 5-year integrated vector management (ivm) project was implemented in pondicherry, south india, for the control of bancroftian filariasis. the efficacy of the ivm strategy was compared with routine control strategy under the national programme. the present paper describes the pre-control epidemiological features of filariasis as determined by a mass blood survey in 1981. of 24946 persons examined 8.41% were microfilaraemic. microfilaraemia prevalence was homogeneous throughout the study area. t ... | 1989 | 2691269 |
| bancroftian filariasis in pondicherry, south india: 2. epidemiological evaluation of the effect of vector control. | this article examines the evaluation of a bancroftian filariasis control programme undertaken in pondicherry from 1981-5. integrated vector management was applied in one half of the town, and routine operations under the national programme (larviciding and chemotherapy) continued in the comparison area. the programme was evaluated by monitoring relative change in the epidemiological statistics of both populations. the results indicate that there was significant reduction in prevalence of microfi ... | 1989 | 2691270 |
| control of bancroftian filariasis by diethylcarbamazine medicated common salt in karaikal, pondicherry, india. | a trial of diethylcarbamazine (dec) mixed in crystal common salt at a concentration of 0.15 to 0.2 per cent was carried out for 46 months (1982 to 1986) in karaikal town and five commune panchayats of pondicherry for control of bancroftian filariasis. comparison of pre and post trial surveys showed 97.6 per cent reduction of microfilaria rate. no microfilaria or disease case was found in less than 5 years age group in the post trial survey. there was about 72 per cent reduction of disease rate. ... | 1989 | 2693530 |
| microfilaraemia, serum antibody and development of clinical disease in microfilaraemic subjects infected with wuchereria bancrofti and treated with diethylcarbamazine citrate. | a seroepidemiological survey of bancroftian filariasis was carried out in 2 townships in sri lanka with the objectives of determining the microfilaraemia rates, dependence on age and sex, susceptibility to re-infection, effect of diethylcarbamazine therapy on serum antibodies to microfilarial surface antigens, and the predictive value of the indirect fluorescent antibody test. the mean microfilaraemia rate was 5.4%. microfilaraemia was not sex-dependent but a marginally elevated incidence was se ... | 1989 | 2694470 |
| vector competency of culex quinquefasciatus (haitian strain) following infection with wuchereria bancrofti. | 1989 | 2694503 | |
| estimation of age-specific rates of acquisition and loss of wuchereria bancrofti infection. | this study uses a reversible catalytic model to estimate the age-specific rates of gain and loss of wuchereria bancrofti infection from data collected during a control programme in pondicherry, south india. the data describe the infection status in 1981 and 1986 of two cohorts of individuals, one living in an area where vector reduction had been achieved, and the other in a comparable endemic area. the rate of loss of infection in the absence of reinfection is estimated for the cohort in the con ... | 1989 | 2694504 |
| a simple deterministic model for host-parasite relationship in wuchereria bancrofti infection & its relevance to parasite regulation in human host. | a deterministic immigration-death model, which reflects the population dynamics of w. bancrofti in human host has been applied to study the relationship between vector and human infections. application of the model showed that the rate of acquisition and loss of human infection were approximately equal (l = 0.130 and m = 0.129). the relationship of infective resting density (ird) in vector population with maximum intensity (imax) of infections and microfilaria prevalence (mfp) in human populatio ... | 1989 | 2695460 |
| detection of wuchereria bancrofti antigen in serum and finger prick blood samples by enzyme immunoassay: field evaluation. | we have recently reported that a monoclonal antibody-based enzyme immunoassay for detection of filarial antigen in human serum is sensitive and specific for active infection with wuchereria bancrofti. the present studies were undertaken to assess the feasibility of testing whole blood collected by finger prick in this assay. a preliminary study was performed to compare antigen test results obtained with whole blood, blood dried on filter paper, and serum. results obtained with anticoagulated who ... | 1989 | 2696080 |
| specific detection of human antibodies to onchocerca volvulus. | specific diagnosis of antibodies to onchocerca was achieved through (1) the construction of direct and indirect elisa systems, and (2) restricting elisa assays to the igg4 class. the direct elisa was based on the isolation of a surface derived, low molecular weight surface antigen preparation containing two main antigens (m. wt. 16.2 and 12.8 kda) as defined by western blot analysis. the direct elisa system detected antibodies in children of six years old, and may therefore be applicable to dete ... | 1989 | 2696081 |
| further evidence of a skewed distribution of microfilariae in capillary blood. | reported are results for 23 haitian patients with capillary wuchereria bancrofti microfilaremias greater than 30 mf/20 cmm blood. in capillary blood, the number of microfilariae was 0.9 to 7.8 times greater than expected when compared with that in venous blood. when the values for venous blood and capillary blood from these high count patients were plotted, the simple linear regression y = a + bx (r2 = .36) and the exponential function y = aebx (r2 = .34) both represented the relationship. howev ... | 1989 | 2696082 |
| relationship of c3 & c4 levels with filarial immune complexes in bancroftian filariasis. | c3 and c4 levels were determined by radial immuno-diffusion technique and filarial circulating immune-complexes by anti-c3 elisa in microfilaraemic individuals and patients with clinical filariasis. decreased levels of c3 and c4 were observed in both groups of filarial patients. low levels of complement components were associated with low levels of circulating immune complexes. | 1989 | 2697689 |
| [further study on in vitro culture of third-stage larvae of wuchereria bancrofti and brugia malayi]. | this paper reported on improved in vitro culture system of human lymphatic filarial larvae. four culture systems were used. third-stage larvae of brugia malayi were best maintained, developing and molted twice in the medium containing modified rpmi-1640 medium, supplemented with 20% newborn calf serum and human embryonic kidney cell line as feeder layer. this culture system kept larvae alive up to 54 days. brugia malayi third-stage larvae began to moult on the 8-10th day and again on the 32-36th ... | 1989 | 2699281 |
| [assessment of intracutaneous test in longitudinal surveillance for lymphatic filariasis]. | in order to evaluate the usefulness of intracutaneous test (it) in longitudinal surveillance of filariasis, two administrative villages selected from queshan county, henan province of china, endemic for wuchereria bancrofti, were surveyed in 1982, 1983 and 1987 respectively, by it with antigen fpt derived from dirofilaria immitis. the result showed that the original level of it to antigen fpt in the population was consistent with the data of either etiological or entomological investigation befo ... | 1989 | 2699282 |
| epidemiology of bancroftian filariasis in a semi-urban community of kerala state. | a community-based longitudinal study was initiated in 1983 in a semi-urban area, endemic for bancroftian filariasis to determine the incidence and prevalence, natural history and clinical pattern of filarial infection and also to study the impact of control measures on it. the base-line filariometric indices observed during the initial clinico-parasitological survey and entomological observations made during the first 12 months of this study are highlighted in this paper. 5.5 per cent of the exa ... | 1989 | 2700479 |
| filariasis control in rural areas through detection and treatment with diethylcarbamazine. | a pilot study for control of bancroftian filariasis through detection and treatment of microfilaria (mf) carriers and filaria disease cases with diethylcarbamazine (dec) undertaken in the rural areas of srikakulam and vizianagaram of andhra pradesh showed that this chemotherapeutic method of control of filaria in rural areas is feasible and acceptable to society. during first round of detection and treatment 20,300 mf carriers (90.6 per cent of detected) and 6,588 disease persons (86 per cent of ... | 1989 | 2700480 |
| onchocerca volvulus heat shock protein 70 is a major immunogen in amicrofilaremic individuals from a filariasis-endemic area. | infestation with organisms causing lymphatic filariasis (i.e. wuchereria bancrofti and brugia malayi) results in a variety of clinical presentations. it is possible that some of the variation is due to differences in host response to parasite. to determine whether individuals who live in an endemic area but differ in their clinical manifestations respond to different filarial antigens, we screened onchocerca volvulus expression libraries with sera from a number of individuals belonging to differ ... | 1989 | 2704388 |
| [a study of ivermectin in the treatment of lymphatic filariasis due to wuchereria bancrofti var. pacifica in french polynesia]. | forty carriers of 20 or more w. bancrofti var. pacifica per ml were blind administered ivermectin at 50, 100, 150 or 200 mcg/kg doses. the rate of successful treatment was 100% with the 4 dosages. the percentage cure rate and the decrease percentage in the microfilarial count were significantly higher in persons treated with 100, 150 and 200 mcg/kg than in persons treated with 50 mcg/kg. frequency and intensity of side-reactions were similar to those observed during treatment with dec; they were ... | 1989 | 2743520 |
| the lymphatic filariases. | 1985 | 2860339 | |
| prospects of human malaria and bancroftian filariasis infections in the lower rufiji basin, tanzania ii. bancroftian filariasis. | surveys for human bancroftian filariasis infections were conducted in the lower rufiji basin, tanzania, before and after the long rains in 1981. a multipurpose water resources development project has been planned in the area. a microfilarial rate of 18.1%, a mean microfilarial count of 80 microfilariae per 100 microliters blood were observed. generally, males showed higher microfilarial rates than their female counterparts. all microfilariae were identified as wuchereria bancrofti. a prevalence ... | 1985 | 2863884 |
| [estimation of the transmission intensity of bancroftian filariasis in queshan county, henan province]. | 1985 | 2874901 | |
| dose-ranging study of ivermectin in treatment of filariasis due to wuchereria bancrofti. | 1987 | 2883362 | |
| lectin-binding characteristics of wuchereria bancrofti microfilariae. | the binding of 10 different lectins to the surface of microfilariae of wuchereria bancrofti has been investigated. wheat germ agglutinin (wga) and helix pomatia lectin (hpa) bound specifically to the sheathed microfilariae indicating the presence of n-acetyl-d-glucosamine and n-acetyl-d-galactosamine respectively on the surface. exsheathed microfilariae did not react with any of the lectins. treatment of sheathed microfilariae with proteases resulted in increased binding of wga and hpa. such tre ... | 1987 | 2884837 |
| epidemiology of lymphatic filariasis. | human lymphatic filariasis is caused mainly by wuchereria bancrofti, brugia malayi and brugia timori. of the estimated 90.2 million people infected, more than 90% have bancroftian and less than 10% brugian filariasis. the distribution and transmission of the disease are closely associated with socioeconomic and behavioural factors in endemic populations. urban w. bancrofti infection, as seen in south-east asia, is related to poor urban sanitation, which leads to intense breeding of culex quiquef ... | 1987 | 2885159 |
| [lymphatic filariasis in vanuatu]. | lymphatic filariasis, in the archipelago of vanuatu, is due to wuchereria bancrofti. the vector is anopheles farauti, endophilic mosquito, which transmits also malaria. the level of endemicity was very high in the beginning of this century (microfilariae in blood: 60.9%, elephantiasis: 21%), and has dramatically decline now by detection and treatment of sick people (70 cases in 1986), mass chimioprophylaxis and protection against the vectors. but these actions must be continued to obtain the era ... | 1987 | 2894256 |
| application of biotechnology in the identification of filarial larva in mosquitoes. | current methods for detecting and identifying filariae in mosquitoes are laborious and time consuming. with today's technology, we can reasonably expect development of rapid, sensitive and specific assays for detecting and identifying filariae in naturally infected mosquito populations. progress in developing such assays is reviewed. | 1988 | 2900557 |
| bancroftian filariasis in the igwun basin, nigeria. an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-month field and laboratory study was carried out to determine the epidemiology, clinical features, and transmission dynamics of bancroftian filariasis in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for clinical signs of filariasis. 690 day provocative blood samples (dps), and 728 night blood samples (nbs) were examined for microfilaremia. 14.3% of males and 11.1% of females were mf positive. 5.8% of dps, and 19.5% of the nbs were mf posi ... | 1988 | 2901204 |
| investigations of filarial worms of man in metropolitan lagos. short communication. | 1988 | 2901210 | |
| microfilaraemia, filarial antibody, antigen and immune complex levels in human filariasis before, during and after dec therapy. a two-year follow-up. | a study on the effect of dec therapy on microfilaraemia and the immune status in 27 patients with w. bancrofti infection was carried out for two years. persistence of microfilaraemia was observed in 4 out of 27 cases after one course of dec therapy and were treated again for one week. on further follow-up, none was microfilaraemic upto day 60. the mean filarial antibody titres of igm and igg showed a gradual decrease as assessed by enzyme linked immunosorbent assay (elisa). the mean titres of ci ... | 1988 | 2903626 |
| a study of bancroftian filariasis on the islands of batan and rapu rapu, philippines. | the islands of batan and rapu rapu in southeastern luzon, philippines, were surveyed for filariasis from november 1984 to may 1985. microfilariae of bancroftian filariasis were detected in 10.5% of the people over one year of age. microfilarial rates and intensity of infection were the same for males and females. the highest rates for both sexes were in the 56- to 60-year-old age group. aedes poicilius, which breeds in abaca and banana plants, was found to be very anthropophilic, comprising 96.5 ... | 1988 | 2906482 |
| quantitation of antibodies to infective larvae in wuchereria bancrofti filariasis. short communications. | 1988 | 2907266 | |
| filariasis programme--recife--brazil. | 1987 | 2908187 | |
| reduced lymphocyte response to mitogens in patients with bancroftian filariasis. | peripheral blood lymphocytes from patients with acute and chronic wuchereria bancrofti infections responded poorly to concanavalin a, phytohaemagglutinin and pokeweed mitogen when cultured in heat-inactivated pooled normal serum. the lymphocyte response to mitogens in carriers of microfilariae (mff) were normal. the suppression of transformation to mitogens was not reversible by the removal of plastic adherent cells. incubation with mitogens and the adult filarial worm antigen (bma) did not alte ... | 1986 | 2941905 |
| defective concanavalin a-induced suppression in bancroftian filariasis. | a concanavalin-a-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. the reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients. | 1987 | 2956197 |
| a study of arthritis in papua new guinea. | a study was undertaken of 182 melanesian patients with arthritis who were admitted to three major hospitals in papua new guinea between 1977 and 1982. there were 118 male and 64 female subjects, whose mean ages were 29 years and 25 years respectively. a diagnosis was made in 101 cases (55.5%) but in 81 cases, because assessment and management had been inadequate, a diagnosis could not be made. the commonest cause was infectious arthritis (44%), followed by rheumatoid arthritis (14%), gout (8%), ... | 1987 | 3039954 |
| filariasis in the igwun river basin, nigeria: an epidemiological and clinical study with a note on the vectors. | in a cross-sectional, epidemiological and parasitological study of human filariasis, 845 individuals were examined in settlements along the igwun basin, imo state, nigeria. four different filarial nematode species were identified. two hundred and fifty-six (30.3%) of the individuals examined were positive for onchocerca volvulus, 113 (13.4%) for mansonella perstans, 76 (9.6%) for wuchereria bancrofti and 77 (9.1%) for loa loa. microfilarial rates increased with age of individuals and showed a te ... | 1988 | 3041931 |
| diagnosis of bancroftian filariasis by detection of circulating antigens by counterimmunoelectrophoresis. | 1988 | 3047273 | |
| bancroftian filariasis in the igwun basin, nigeria: an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-months study on bancroftian filariasis was carried out in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for microfilaremia and clinical filarial stigmata. there were 14.3% and 11.1% male and female point prevalence rates, respectively, and an overall prevalence of 12.8%. prevalence rates and microfilarial density increased with age. the highest mff density of 35 mff/20 ml blood occurred in the 40-49 year old male individuals. disease rates ... | 1988 | 3049274 |
| evaluation of integrated vector control measures on filariasis transmission in pondicherry. | 1988 | 3049328 | |
| persistence of microfilaremia in bancroftian filariasis after diethylcarbamazine citrate therapy. | of 58 patients in leogane, haiti, infected with wuchereria bancrofti and treated with diethylcarbamazine citrate (dec-c) at 6 mg/kg per day for 12 days (= 72 mg/kg), 38 (66%) of 58 continued to harbor low numbers of circulating microfilariae (median microfilariae could be demonstrated in 7 (37%) of 19 patients, with a median microfilarial density of 8 mf/ml. three patients who continued to have circulating microfilariae after two courses of dec-c were treated a third time. two (67%) of the three ... | 1988 | 3051291 |
| a quantitative analysis of the diagnostic value of diethylcarbamazine provocation in endemic wuchereria bancrofti infection. | the efficiency (delta) of the day-time provocative effect of diethylcarbamazine (dec) on the circulation of microfilariae (mf) of nocturnally periodic wuchereria bancrofti compared with the night mf count was evaluated in terms of sensitivity and specificity. in one test, the mean mf count for finger-blood samples from the same person on 3 successive nights was compared with the day-time post-dec count; another test compared the mf count in one night-time finger-blood sample with the following d ... | 1988 | 3051541 |
| factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 1. uptake of microfilariae. | ingestion of wuchereria bancrofti microfilariae (mf) from humans by 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus was investigated. the mf densities in blood fell into 3 groups; 0-32mf/ml, 107-122 mf/ml and 421-1140 mf/ml. in an. gambiae and an. arabiensis percentage of mosquitoes ingesting mf was strongly associated with mf density in host blood; in an. melas the association was much weaker. mean number of mf ingested per mosquito was also strongly correlated to mf ... | 1988 | 3051542 |
| factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 2. damage to ingested microfilariae by mosquito foregut armatures and development of filarial larvae in mosquitoes. | microfilariae (mf) of wuchereria bancrofti from the midgut of 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus were examined immediately after the mosquitoes had fed on carriers with different densities of mf. the percentages of mf damaged during ingestion were 57.1-60.0 in an. gambiae, 33.3-50.6 in an. arabiensis and 38.7-55.7 in an. melas. in each species the percentage of mf damaged was independent of mf density in the human host. a further 3657 an. gambiae, 2875 an ... | 1988 | 3051543 |
| [study on the role of low density microfilaremia cases in the transmission of filariasis in late stage of filariasis control]. | 1988 | 3052910 | |
| circulating antibodies and antigens in presbytis monkeys infected with the filarial parasite wuchereria bancrofti. | levels of circulating filarial antigen, and humoral antibody to other defined antigenic targets, were measured over the course of experimental infection of three presbytis cristatus monkeys with wuchereria bancrofti. circulating antigen levels, measured with an anti-phosphorylcholine monoclonal antibody, varied widely although all animals were positive for some period of the infection. circulating antigen levels tended to be inversely related to the titre of anti-phosphorylcholine antibody, and ... | 1988 | 3057591 |
| uptake and development of wuchereria bancrofti in aedes aegypti and haitian culex quinquefasciatus that were fed on a monkey with low-density microfilaremia. | colonized mosquitoes of culex quinquefasciatus (haitian strain) and aedes aegypti (liverpool strain) were blood fed on a patas monkey (erythrocebus patas) that had been experimentally infected with the haitian strain of wuchereria bancrofti and harbored a consistently low microfilaremia (1-3 mf per 20 mm3). both species ingested more than twice the expected number of microfilariae (mf), i.e. 1.9 and 0.77 mf per mosquito, respectively. however, at 10-16 hours post ingestion only 4.2% of the mf ha ... | 1988 | 3057592 |
| comparative densities of wuchereria bancrofti microfilaria in paired samples of capillary and venous blood. | concurrent finger-prick and venous blood samples were obtained from 43 patients infected with wuchereria bancrofti. microfilariae were counted in blood smears and on nuclepore filters. based on the numbers of microfilariae in 20-microliters finger-prick samples, an expected (theoretical) number of microfilariae in venous samples was calculated. this expected value was compared to the actual number of microfilariae present in venous blood. the actual number of microfilariae present ranged from 0. ... | 1988 | 3067320 |
| practical and effective dose schedule of diethylcarbamazine (dec) against bancroftian filariasis for mass therapy campaigns. | 1988 | 3068306 | |
| [an unusual case of mediastinal lymphatic filariasis with pulmonary artery stenosis]. | 1988 | 3068713 | |
| use of mebendazole in combination with dec in bancroftian filariasis. | 1988 | 3071522 | |
| [studies on the indirect fluorescent antibody test for diagnosis and surveillance of human filariasis]. | 1988 | 3072113 | |
| lymphatic filariasis: some recent trends and advances. | 1988 | 3073871 | |
| epidemiology of wuchereria bancrofti in leogane, haiti. | a survey for wuchereria bancrofti in leogane, haiti, revealed that 140 of 421 individuals (33%) had a patent infection, of which 40% lived in the suburban outskirts of the city. the median microfilaria density was 19.1 per 20 mm3 of blood for suburban dwellers compared with only 8.8 for those living in the city. the vector, culex quinquefasciatus (say), breeds mostly in and around numerous rum distilleries, located exclusively around the periphery of the city, and this undoubtedly accounts for t ... | 1988 | 3075358 |
| the effect of diethylcarbamazine treatment of bancroftian filariasis on the immunological reactivity of microfilaraemic individuals. | patent filarial infection has been correlated with a profound suppression of humoral and cellular responses to filarial antigens. in the present study, the filarial antigen-specific humoral and cellular reactivity of 30 haitian subjects with patent wuchereria bancrofti infection was monitored before and after treatment with diethylcarbamazine. microfilarial density was reduced from a pre-treatment mean of 1778/ml to 9/ml, with residual microfilaraemias detectable in 10 subjects. peripheral blood ... | 1988 | 3075359 |
| diethylcarbamazine prophylaxis against bancroftian filariasis given by a member of the local community in kenya. | 1988 | 3075443 | |
| [diagnosis of filariasis by indirect fluorescent antibody test with sonicated microfilariae malayi as antigen]. | 1988 | 3075522 | |
| [transectional surveillance in west hubei with filariasis basically eradicated]. | 1988 | 3075527 | |
| detection of infective larval antigens in bancroftian filariasis. | 1988 | 3076164 | |
| wuchereria bancrofti larvae in naturally infected culex quinquefasciatus. | 1988 | 3076752 | |
| nodules in the conjunctiva, bung-eye, and bulge-eye in africa caused by mansonella perstans. | eight patients from uganda, sudan, nigeria, and zaire presented with swelling of the eyelids, proptosis, or conjunctival granulomas. in 5 patients the cause was mansonella perstans; in 1, it was a wuchereria bancrofti-like worm; and in 2, an unidentifiable worm. the morphologic features and histopathologic changes in the conjunctiva and periorbital fat are described and illustrated. | 1988 | 3079314 |
| persistence of parasite antigenemia following diethylcarbamazine therapy of bancroftian filariasis. | this study was designed to reexamine the efficacy of diethylcarbamazine for bancroftian filariasis with special reference to changes in serum parasite antigen levels and antifilarial antibody titers after treatment. patients with asymptomatic microfilaremia were treated with 6 mg/kg diethylcarbamazine daily for 12 days. microfilaria counts fell dramatically after treatment, as expected. igg antibody titers to adult and microfilarial antigens of b. malayi were increased 1 month after treatment in ... | 1988 | 3079315 |
| demonstration of species-specific and cross-reactive components of taenia solium metacestode antigens. | analysis of human serum reactivities to antigenic components of soluble taenia solium metacestode proteins showed the predominant presence of determinants shared by t. solium, echinococcus multilocularis and e. granulosus. two polypeptides were demonstrated by sds-page and western blot or enzyme-linked immunoelectrotransfer blot (eitb) assay to bind serum and csf antibodies only from t. solium cysticercosis patients. these species-specific antigenic polypeptides focused between ph 4.6 and 3.9 af ... | 1986 | 3082229 |
| two additional morphological characteristics for differentiating adult wuchereria bancrofti and brugia malayi. | 1986 | 3100162 | |
| differentiation of three developmental stages of bancroftian and malayian filariae in mosquito vectors. | 1986 | 3100178 | |
| [advances in research on the immunopathogenic mechanism of lymphatic filariasis]. | 1986 | 3103893 | |
| an egg surface antigen of setaria digitata (filariae) shed on development to microfilariae. | egg surface antigens of setaria digitata were investigated by an immunoperoxidase staining technique. certain antigens on the egg surface were shed when the eggs developed to microfilariae. rabbit antisera to s. digitata eggs and to the soluble egg antigen reacted (as detected by immunoperoxidase staining) with the surface antigens of s. digitata eggs and immature microfilariae, and with mature microfilariae of wuchereria bancrofti and dirofilaria repens, but not with the surface antigens of mat ... | 1988 | 3256115 |
| bancroftian filariasis in haiti: preliminary characterization of the immunological responsiveness of microfilaremic individuals. | patent infections with the lymphatic filariae, wuchereria bancrofti and brugia malayi, are associated with suppressed in vitro cellular responsiveness to filarial antigens. in studies of bancroftian filariasis in haiti, a significant number of microfilaremic individuals can be characterized as "responders" to filarial antigens. cells from 37/74 untreated microfilaremic subjects responded to b. pahangi antigen (stimulation ratio greater than 2) as detected by in vitro blastogenesis. a comparison ... | 1988 | 3277457 |
| cytologic diagnosis of bancroftian filariasis in a nonendemic area. | parasitic infections are common in the developing countries, but the cytologic diagnosis of such infections is infrequent or rare. this paper presents four cases of filariasis caused by wuchereria bancrofti diagnosed by cytologic examination and discusses some unusual observations. the finding of microfilariae in pleural fluid in the absence of the classic symptoms and signs of tropical pulmonary eosinophilia is highlighted. in two patients, nocturnal microfilaremia could not be demonstrated des ... | 1988 | 3279714 |
| lymphatic filariasis: detection of circulating and urinary antigen and differences in antibody isotypes complexed with circulating antigen between symptomatic and asymptomatic subjects. | a two-site immunoradiometric assay using a monoclonal antibody (moab) against brugia malayi microfilariae allowed the detection of parasite molecules both in the serum and the urine of patients from sri lanka infected with wuchereria bancrofti. whereas 50% of patients had no antigen in their serum, all of them excreted detectable amounts of antigen in their urine, the levels being higher in symptomatic than in asymptomatic patients. the poor detection in serum appeared to be related to the prese ... | 1988 | 3280185 |
| antibodies to diethylcarbamazine cross-react with microfilariae of wuchereria bancrofti. | antibodies directed against the microfilarial sheath have been instrumental in the immune elimination of circulating microfilariae in human lymphatic filariasis. we report here that antibodies to diethylcarbamazine (dec, the most commonly used anti-filarial drug) cross-react with the sheath of wuchereria bancrofti microfilariae. antibodies with reactivity to dec were raised in rabbits by immunization with a conjugate of methylpiperazine carboxylic acid (mpca, an acid hydrolysis product of dec) c ... | 1988 | 3280479 |
| filarial antigen in circulating immune complexes from patients with wuchereria bancrofti filariasis. | detection of filarial antigen in circulating immune complexes from patient sera was performed by an enzyme immunoassay in which the immune complexes were precipitated in the cold with polyethylene glycol and then dissociated in an acid ph buffer before being added to an elisa plate. the dissociated antigen bound to the plate where it could be detected by peroxidase-labeled polyclonal rabbit antifilarial antiserum. control sera used for defining the specificity of the assay included sera with imm ... | 1988 | 3281495 |
| analysis, characterization, and diagnostic utility of filarial antigen fractions isolated from immune complexes in bancroftian filariasis. | circulating immune complexes isolated from clinical filarial patients' sera by 3% polyethylene glycol precipitation were analyzed by sds-polyacrylamide gel electrophoresis (sds-page) on vertical slab gel. silver staining of the gel after electrophoresis revealed 20 and 30 protein bands without and with reduction of immune complexes, respectively, in the molecular weight range of 148-18k. filarial antigen in protein eluates from gel slices was detected by sandwich enzyme-linked immunosorbent assa ... | 1988 | 3282713 |
| ivermectin for the treatment of wuchereria bancrofti filariasis. efficacy and adverse reactions. | ivermectin treatment was evaluated for efficacy and side effects in 40 patients in south india who had microfilaremia and bancroftian filariasis. ivermectin was administered once orally at four dose levels (range, 25 to 200 micrograms/kg), and at each it was found to be completely effective in clearing blood microfilariae within five to 12 days. in most patients, microfilariae reappeared by three months; by six months the levels averaged 14% to 32% of pretreatment values in the four study groups ... | 1988 | 3285045 |
| [upper extremity lymphedema in bancroftial filariasis]. | 1988 | 3286402 | |
| evaluation of elisa and ihat in immunodiagnosis of bancroftian filariasis using delipidized l. carinii antigen. | 1988 | 3286786 | |
| vector competence to wuchereria bancrofti in culex pipiens collected from the nile delta. | 1988 | 3286788 | |
| [an epidemiological survey of filarial chyluria]. | 1988 | 3289747 |