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[ocular manifestations caused by migrating larva of toxocara canis]. 19694901863
immediate hypersensitivity and serological responses in guinea pigs infected with toxocara canis or trichinella spiralis. 19654953925
antigenic analysis of a metazoan parasite, toxocara canis. i. extraction and assay of antigens. 19674961050
toxocara skin sensitivity tests and other observations in animals experimentally infected with toxocara canis. 19674965930
immunological response of rabbits to toxocara canis infection. 19684966889
purification and immunochemical analysis of a genus-specific cuticular antigen of toxocara canis. 19694978144
further toxocara skin sensitivity tests in animals experimentally infected with toxocara canis. 19694978467
studies on the liver, lung, brain and blood of experimental animals infected with toxocara canis. 19694986046
toxocara canis infections in baboons. ii. distribution of larvae and histopathologic responses. 19704989284
precipitin reactions in monkeys (macaca sinica) experimentally infected with toxocara canis and in children with visceral larva migrans syndrome. 19704991128
ocular toxocara canis. i. experimental immunology. 19715005931
invasion of the spinal cord of mice by toxocara canis. 19725022883
[findings related to the 1st ecdysis of ascaris lumbricoides, a. suum and toxocara canis larvae]. 19725049297
[visceral larva migrans, toxocara canis (werner, 1782) in man]. 19725063627
[chronic endophthalmitis due to toxocara canis]. 19725065031
[a further case of endophthalmos due to toxocara canis]. 19725080363
infection of dogs by toxocara canis carried by flies. 19715091367
[chronic endophthalmitis caused by toxocara canis]. 19715316934
visceral larva migrans--an immunofluorescent examination of rabbit and human sera for antibodies to the es antigens of the second stage larvae of toxocara canis, toxocara cati and toxascaris leonina (nematoda). 19665327555
infections of toxocara canis in dogs fed infected mouse tissues. 19695357321
infections of toxocara canis in dogs fed infected mouse tissues. 19695374712
correspondence scientific, toxocara canis as a support for cholelithiasis in the dog. 19695387809
[pseudoglioma of the retina caused by toxocara canis. description of a suspected case]. 19695406016
toxocara canis transmitted by the common house-fly to the canine host. 19705442108
an improved hemagglutination technique for detecting antibody against toxocara canis. 19705443074
toxocara canis infection in baboons. i. antibody, white-cell, and serum-protein responses following infection. 19705443075
visceral larva migrans (toxocara canis) in calves. 19705462751
resistance of mice to toxocara canis: effect of prechallenge infections and injections of worm extracts. 19705471781
toxoplasmal and toxocaral infections: a clinical investigation into their relationship.an investigation was carried out to determine whether a relationship existed between infections with toxoplasma gondii and toxocara canis. antibodies were sought by the toxoplasma dye test and the toxocara skin sensitivity test. sixty-seven patients were examined in the united kingdom; 38 had positive toxoplasma dye tests, two of these being toxocara-positive; and 29 had negative dye tests, six of them being toxocara-positive. from the total of eight toxocarapositive patients antibodies to toxop ...19705475821
hypersensitivity to some nematode antigens.immediate and delayed skin reactions to antigens derived from ascaris suum, necator americanus, and toxocara canis are described in three subjects and related to eosinophil counts and serum ige levels. one, who had laboratory contact with ascarides but no known infection, gave positive immediate reactions to all three antigens. another, following repeated experimental infection with necator, gave positive immediate reactions to all three antigens and a delayed reaction to necator alone. the thir ...19715541233
age resistance to toxocara canis in ascarid-free dogs. 19715567417
heterophile antibodies in toxocara canis infection in rabbits. 19685669563
experimental studies on toxascaris leonina. iv. development of eggs of three ascarids, t. leonina, toxocara canis and toxocara cati, in dogs and cats. 19685692326
experimental toxocariasis. i. some observations on the histopathology of the migration of toxocara canis larvae in the mouse. 19685706750
experimental toxocariasis. ii. toxocara canis in the mouse as a system for testing compounds of potential anthelmintic acitivity. 19685706751
experimental studies on toxascaris leonina. vi. experimental infection of mice, chickens and earthworms with toxascaris leonina, toxocara canis and toxocara cati. 19685750134
immunological response of the hosts to toxocara canis (werner, 1782) infection. i. effect of superinfection on naturally infected puppies. 19685754272
toxocara canis infection in a jamaican child. 19695821281
[case of extreme eosinophilia in toxocara canis infestation]. 19655851202
[intraocular toxocara canis infestation]. 19655895724
effect of toxocara canis infection on the ability of white rats to solve maze problems. 19665925491
infection with adult toxocara canis. 19665940227
[the development of the canine ascarid toxocara canis (werner 1782) in the adequate and non-adequate host. experimental chemotherapeutic influencing of its larvae ("larva migrans visceralis") in the animal experiment (mouse)]. 19665974165
the migratory behaviour of the larvae of toxocara canis (werner 1782) in white mice. 19665980873
[clinical case with parasitological confirmation of migratory visceral larva caused by toxocara canis in colombia]. 19665990128
[localization in the brain of the guinea pig of 2nd stage larvae of toxocara canis (werner, 1782). electroencephalographic, parasitological and anatomo-histopathological documentation]. 19665991288
the prenatal migration of toxocara canis larvae and their relationship to infection in pregnant bitches and in pups. 19666006715
anaphylactic and reagin-like antibody in rats infected with toxocara canis larvae. 19676017229
incidence of toxocara canis and other helminth parasites of dogs in mexico city. 19676035723
human toxocara canis encephalopathy in a case of visceral larva migrans. 19676066953
[toxocara canis of the eye]. 19676080326
a collaborative study on larval excretory/secretory antigens of toxocara canis for the immunodiagnosis of human toxocariasis with elisa.two batches of excretory/secretory (e/s) antigens from second stage larvae of toxocara canis maintained in vitro were prepared independently in two different laboratories (zürich and basel) and analysed in order to obtain information for future efforts to standardize the enzyme-linked immunosorbent assay (elisa) used for the serodiagnosis of human toxocariasis. sds-page and "western-blotting" revealed at least 10 different antigenic components common to the two antigen preparations. however, dis ...19846084948
immunodiagnosis of parasitic zoonoses: sensitivity and specificity of in vitro lymphocyte proliferative responsiveness using nematode antigens purified by affinity chromatography.the sensitivity of in vitro lymphocyte proliferative responsiveness using antigens purified by affinity chromatography, was greater than that of three serological tests and allowed the specific identification of dirofilaria immitis, toxocara canis, angiostrongylus cantonensis and ascaris lumbricoides in animals sensitized with parasite antigens, and the diagnosis of natural (d. immitis, t. canis and angiostrongylus cantonensis) and zoonotic nematode infections. lymphocytes remained viable in who ...19816168047
spleen cell responses in experimental murine toxocariasis.splenic responses of cba/j mice infected with 250 embryonated ova of the nematode, toxocara canis were characterized during the first month post-inoculation (p.i.). by the 6th day of infection, spleen to body weight ratios were over 3.5 times greater in infected mice than uninfected controls. this ratio peaked at 5.0 on day 14 and declined slightly by day 36 p.i. lymphocyte transformation studies were carried out using the t cell mitogens, con a and pha and the b mitogen, lps. the responses of i ...19846334150
[visceral larva migrans due to toxocara canis. study of the clinical and laboratory characteristics of 7 human cases]. 19846335760
ocular toxocariasis: a review of the literature.ocular toxocariasis is invasion of the eye by the larvae of the toxocara canis worm. since its initial description 31 years ago, many cases involving all segments of the eye have been reported. most age groups have been affected, although it is generally a childhood disease. its distribution is worldwide. several tests have been devised for its detection, but only recently with a degree of success. many treatments have been proposed, but more evaluation is necessary. this review correlates histo ...19836342500
immunodiagnosis of parasitic zoonoses: purification of toxocara canis antigens by affinity chromatography. 19836343270
dirofilaria immitis: performance and standardization of specific antibody immunoassays for filariasis.the factors associated with the development, optimization, and validation of immunoassays for the detection of parasite-specific antibody in filariasis infections were investigated using the dog heartworm, dirofilaria immitis as a model. we examined two assays, the protein a solid-phase radioimmunoassay (spria) and enzyme-linked immunosorbent assay (elisa), for quantitation of specific antibody to the parasite in canine serum. precision, reproducibility, and parallelism were examined using respo ...19836357832
the production of human a and b blood group like substances by in vitro maintained second stage toxocara canis larvae: their presence on the outer larval surfaces and in their excretions/secretions.in vitro maintained second stage toxocara canis larvae do not bind polyclonal anti-human a or b blood group antibodies onto their outer surface at 37 degrees c as detected by indirect fluorescence. when larvae are incubated at 2 degrees c under the same experimental conditions, intense fluorescence over the whole outer surface is observed. re-incubation of such larvae at 37 degrees c results in a gradual loss of surface fluorescence. this loss is complete after 3 h. the excretions/secretions (es ...19836360442
evaluation of the enzyme-linked immunosorbent assay for detecting antibodies to toxocara canis in dogs. 19836361349
detection of circulating toxocaral antigens in dogs by sandwich enzyme-immunoassay.this study describes the presence of circulating toxocaral antigens (cta) in the sera of dogs infected with toxocara canis (t. canis) by using a sandwich enzyme-immunoassay (seia). a specificity of this assay with different antigens was observed, i.e. the eia values, which express the antigen concentration, of excretory-secretory antigen from t. canis larvae were higher than those of other antigens (ascaris lumbricoides, dirofilaria immitis and fasciola hepatica). the variability in intra-assay ...19846365746
hemoimmuno-adherence test (hiat) for the detection of antibodies anti-toxocara canis l2 larvae.the use of a hemoimmuno-adherence test (hiat) for detecting antibodies anti-l2 larvae of toxocara canis is presented. the hiat allows to reveal the presence of antibodies in the sera of both naturally and experimentally infected animals. the sensitivity of hiat appears to be comparable to that of methods such as immunoenzymatic ones.19836399735
purification and characterization of excretory and secretory antigen of toxocara canis larvae.excretory/secretory (es) antigen of toxocara canis larvae was isolated from the culture medium of second-stage larvae by gel filtration. the antigen induced production of not only igm or igg but also ige antibody. the antigen, when treated with guanidine hydrochloride and 2-mercaptoethanol, lost its allergenic activity but retained an ability to induce igm or igg antibody. purified antigen was of glycoprotein nature and had a molecular weight of 35,000. the whole antigen showed a cross-reaction ...19836411609
interrelationship of eosinophilia and ige antibody production to larval es antigen in toxocara canis infected mice.in order to elucidate the relationship between eosinophilia and ige antibody production in parasitic infection, the degree of eosinophilia and ige antibody levels to larval es antigen of toxocara canis were investigated in eight inbred strains of mice after infection with t. canis. eosinophilia was far higher in degree in sjl mice than in the other inbred strains. however, ige antibody levels to larval es antigen in sjl mice were the lowest among those inbred strains. similarly, the degree of eo ...19846438599
[distribution of migrating larvae of toxocara canis (werner, 1782) in various organs of experimentally infected white mice (author's transl)]. 19806446415
meandering ocular toxocariasis.ocular toxocariasis affects the eye in three recognizable patterns: a peripheral inflammatory mass in a quiet eye, posterior pole granuloma, or painless endophthalmitis. the present case photographically documents a new form of ocular involvement, that of periodic intraretinal meandering, followed by quiescence with encapsulation, reemergence, and renewed migration. the similar behavior of the toxocara canis larva in the animal model and the serologic confirmation of toxocara canis by elisa test ...19846463400
[distribution of toxocara canis in puppies in bulgaria]. 19846465617
effect of thiabendazole on the migration of toxocara canis larvae in the mouse.the effects of thiabendazole on the survival and migration of toxocara canis larvae in mice were studied. although thiabendazole had a negligible larvicidal effect, it produced marked inhibition of the migration of the larvae in tissues. larvae were arrested in the liver after oral inoculation and in the lungs after intravenous inoculation. observations indicated that the drug may have a reversible, as well as a progressive, time-related metabolic effect on the larvae. significant inhibition of ...19846470886
[retinoblastoma--clinical diagnostic errors].the author discusses clinical and histological findings in 6 patients whose complaints had been wrongly diagnosed, out of 91 patients in whom a retinoblastoma had been diagnosed at the ophthalmo-pathological laboratory of the university eye hospital in utrecht between 1960 and 1981. in 6 other cases the diagnosis was doubtful. all the cases occurred before 1974. the faulty diagnoses were: spontaneously necrotized retinoblastoma, congenital anomaly, retinal detachment, infection with toxocara can ...19846482302
immunoradiometric assay for quantitation of dirofilaria immitis antigen in dogs with heartworm infections.an immunoradiometric assay (irma) was developed, optimized, and validated for detection of parasite-specific antigen in sera from hosts with filarial infections, using dirofilaria immitis in dogs as a model. the precision, reproducibility, and parallelism of the irma were examined, using precision profile analysis. the irma had acceptable precision and reproducibility [less than 15% intra-assay coefficient of variation (cv)] over a working range of 10 to 2,000 ng of d immitis-antigen (ag)/ml. th ...19846497105
a five-year analysis of diseases of dogs and cats in the veterinary clinic of freetown, sierra leone.a survey is presented of the diagnoses found in 2938 dogs and 32 cats, treated between january 1976 and january 1980 at the veterinary clinic of freetown. more than one third of the dogs (1175) and 13 cats were infected by ancylostoma spp., whereas toxocara canis and toxascaris leonina were encountered in 236 and 232 dogs, respectively. noteworthy is also the relatively high figure of 12 dogs affected by negri bodies (rabies). it is pointed out that dogs and cats move about fairly freely in the ...19846508729
[visceral larva migrans in childhood: report of 2 cases].reports of visceral larva migrans (vlm) are not frequent in brazil, but the prevalence of this disease may be more common due to poor environmental conditions to which most of the children are exposed. the most common infectious agent is toxocara canis, a parasite of the intestinal tract of dogs. children get infected eating contaminated material with feces of dogs. the ova are swallowed and reach the intestinal lumen of the children. systemic migration occurs by lymphatic or portal circulation ...19846517736
repeated patent infection of adult dogs with toxocara canis.three adult male greyhounds have been repeatedly infected with toxocara canis by oral administration of 100 to 200 infective ova. each infection has become patent as shown by the presence of eggs in faeces. anthelmintic treatment between 7 and 14 weeks after infection yielded an average of 25% of the inoculum as adult worms. these dogs have continued to be fully susceptible to infection despite repeated exposure to this parasite, and despite the presence of serum antibody to both parasite surfac ...19846520377
haematological and serological data from dogs raised worm-free and monospecifically infected with helminths.pups free from helminth infection were obtained by treating the bitch prior to parturition, and the bitch and her pups after whelping, with oxfendazole and praziquantel. they were then housed in an area free from contamination with helminth eggs. freedom from infection was confirmed by necropsy examinations and by serological tests using the enzyme linked immunosorbent assay (elisa). groups of pups were infected with toxocara canis, echinococcus granulosus, taenia ovis, t. pisiformis and t. hyda ...19846525114
prevalence of toxocariasis and echinococcosis among dogs in the niger delta.a sample of 60 dogs in the port harcourt area of the niger delta was examined for intestinal parasites. the high prevalence rates of toxocara canis (56.6%) and echinococcus granulosus (85.0%) in the area are discussed in relation to public health. other parasites found in dogs include toxascaris leonina (3.3%), uncinaria stenocephala (70.0%), dipylidium caninum (88.3%), trichuris vulpis (56.7%), ancylostoma caninum (65.0%) and taenia hydatigenia (43.3%).19846530709
visceral larva migrans: a risk assessment in baton rouge, louisiana.visceral larva migrans, vlm, is a disease of young children. due to lack of awareness of the disease as well as its non-specific symptomology, a survey of the potential risk of acquiring the disease was conducted in the baton rouge, louisiana area. the greatest number of dogs showing positive results to tests for the presence of the eggs of toxocara canis were those less than one year of age. very few of the soil samples collected from twenty different parks/playgrounds were found to contain egg ...19846534905
experimental toxocariasis in mice and its effect on their behaviour.when compared to uninfected controls, mice infected with second-stage larvae of toxocara canis exhibited: (1) impaired motor performance, (2) increased ambulatory activity, (3) a greater relative preference for more exposed areas and (4) a greater overall preference for novel environments. the infected mice also appeared to show less approach-avoidance conflict and seemed less cautious when presented with novel stimuli. these behavioural differences were independent of measures of general health ...19846540073
[mouse strain difference in visceral larva migrans of toxocara canis].the mode of larval migration (visceral larva migrans) in toxocara canis infection was compared for balb/c, c57bl/6, c3h/he, dba/2, nc and balb/c nude mice following oral infection with 400 eggs. the mean recovery of larvae from the liver on day 2 post infection (pi) was not different in terms of the strain, age or sex of the mice. the number of larvae recovered from the liver decreased in all strains on days 6, 12 and 21 pi, but the mean for balb/c and (nc x balb/c) f1 mice was significantly hig ...19846542020
prevalence and survival of toxocara canis eggs in the urban environment of perth, australia.using a technique of proven efficiency no toxocara canis eggs were recovered from a total of 266 sand samples collected from "dog beaches" and parks in the perth urban area. this observation emphasises that the major risk to humans is from an environment in which puppies are found. other observations, made at a heavily contaminated site, showed that the eggs of t. canis disappeared from sandy soil over about 6 months during a period in which it would have been expected that conditions were favou ...19846542727
the migration of larval toxocara canis in mice. i. migration through the intestine in primary infections.toxocara canis second stage larvae (l2) hatched in the stomach of mice and within 2 h reached all parts of the small intestine, the posterior half being the preferred site for larval penetration. following penetration at the base of crypts of leiberkuhn they followed tortuous routes in the lamina propria, and entered the tunica muscularis obliquely. larvae only appeared to be arrested in their migration in the submucosa and lamina propria by an inflammatory reaction composed mainly of lymphocyte ...19846543062
the migration of larval toxocara canis in mice. ii. post-intestinal migration in primary infections.following oral infection of nih mice with toxocara canis embryonated eggs the l2 pass the visceral phase of migration during te first week of infection. larvae reach the liver and lungs and peak in number in these organs 2 and 3 days after infection, respectively. larvae are then dispersed throughout the body and enter the myotropic--neurotropic phase by the 7th day of infection. larvae injected directly into the brain are capable of migrating into the viscera and musculature. considerable patho ...19846543063
antibody responses to toxocara canis using sera from parasite-infected mice and protection from toxocariasis by immunisation with es antigens.evidence for serological cross-reactions between toxocara canis and related nematode parasites has been sought using sera from infected mice and the immunodiagnostic excretory/secretory (es) antigen of t. canis larvae. sera from mice experimentally infected with either t. canis, t. cati, t. pteropodis, toxascaris leonina or ascaris suum were tested for the presence of antibodies to t. canis es antigen by solid-phase radioimmunoassay (ria) or enzyme-linked immunosorbent assay (elisa) using anti-m ...19846543490
anthelmintic effect of levamisole, ivermectin, albendazole and fenbendazole on larval toxocara canis infection in mice.the anthelmintic effects of levamisole (100-50 mg kg-1 live bodyweight), ivermectin (2 mg kg-1 bodyweight), albendazole and fenbendazole (both 100 mg kg-1 bodyweight), were tested against second stage toxocara canis larvae in mice. anthelmintic treatment on days 2 to 7 after infection inclusive resulted in significant (p less than 0.05) retention of larvae in the liver, and fewer larvae migrated subsequently to the brain and the musculature of treated mice compared to untreated controls. most of ...19846546805
toxocariasis: a neglected entity.toxocara canis infects many dogs yet has been seldom implicated as a cause of human disease in new zealand. nine patients with diagnostic titres for toxocara canis who were seen in christchurch hospital over a five-year period are described. ophthalmoscopic signs of toxocaral infection were visible at the optic disc or posterior pole of all ten affected eyes. a localised disciform detachment of the macula or a focal granuloma on the disc or retina were the commonest lesions. vision was reduced t ...19836578425
comparison of counterimmunoelectrophoresis with indirect haemagglutination test in the detection of antibodies in rabbits experimentally infected with various species of ascarids.counterimmunoelectrophoresis (ciep) and indirect haemagglutination (iha) were used for the detection of antibodies in 437 sera of rabbits experimentally infected with ascaris suum, toxocara canis and toxascaris leonina. ciep showed 44.0-52.3% positivity in a. suum, 25.5% in t. canis and 19.7-29.2% in t. leonina infection, whereas the positivity detected by iha was 59.8-90.2% in a. suum, 44.8% in t. canis and 59.6% in t. leonina infection. a comparison of the two tests reveals that ciep is a suit ...19846589203
trapping of large numbers of larvae in the livers of toxocara canis-reinfected mice.congenitally athymic nude mice (balb/c-nu/nu) and balb/c-nu/+ were infected with 500 embryonated toxocara canis eggs. six weeks later they were reinfected with the same number of eggs. the liver and other organs were examined for numbers of 2nd-stage larvae at 2, 4, and 6 weeks after reinfection. far more larvae were trapped in the liver after reinfection than after the primary infection but fewer were found in the livers of balb/c-nu/nu than in balb/c-nu/+ mice.19836603485
ocular toxocara canis infection: clinical and experimental features. 19836604970
sclerosing endophthalmitis in children: computed tomography with histopathologic correlation.three children with histopathologically diagnosed sclerosing endophthalmitis presumably secondary to toxocara canis were studied by orbital computed tomography. the diffuse increased intraocular density present in the ct scans was indistinguishable from that observed in coats's disease and non-calcifying retinoblastoma. although retinoblastoma constitutes the major life-threatening cause of leukocoria in children, a number of other simulating conditions (pseudoglioma) can cause diagnostic confus ...19836605422
toxocara canis endophthalmitis with low elisa titer.a five-year old boy had clinical findings consistent with ocular toxocariasis, blood eosinophilia, and repetitive negative (titer 1:2) elisa. the eye was enucleated and larval fragments consistent with toxocara were present within an eosinophilic granuloma in the vitreous cavity overlying a chorioretinal scar entrance site.19836606373
in vitro interaction of eosinophils from ascarid-infected eyes with ascaris suum and toxocara canis larvae.the role of eosinophils in ocular ascarid infection is studied in an animal model. primary intravitreal infection of guinea-pig eyes with ascarid (toxocara canis, ascaris suum) second-stage (l2) larvae resulted in an anterior chamber exudate containing 98% or more eosinophils. anterior chamber aspirates were cultured in rpmi media 1640 with t. canis or a. suum l2 larvae at 37 degrees c for 1-96 hours. the in vitro interaction of eosinophils with l2 larvae was studied by light, and scanning and t ...19836618795
further observations concerning the diffuse unilateral subacute neuroretinitis syndrome.diffuse unilateral subacute neuroretinitis (dusn) is a clinical syndrome characterized early by visual loss, vitritis, papillitis, and recurrent crops of gray-white retinal lesions and later by progressive visual loss, optic atrophy, retinal vessel narrowing, and diffuse pigment epithelial degeneration. evidence is presented that it is caused by a nematode that is probably not toxocara canis; that at least two nematodes of different sizes are involved; that there are at least two endemic areas f ...19836639421
the accumulation of toxocara canis larvae in the brains of mice. 19836642866
[viscera larva migrans syndrome in children: description of a case].the aa describe a case of larva migrans visceral syndrome in a two year-old boy in systemic form with negative outcome. the autoptic examination showed a "granulomatous hepatitis with marked component of eosinophil cells'. the presence of "eosinophil granuloma' in liver has led to the diagnosis of visceral larva migrans syndrome; other possible causes of ipereosinophilous syndrome have been excluded on the basis of anamnestic, clinic and laboratory data. the discovery in the medical history of f ...19836647089
prevalence of helminth parasites of dogs in lusaka, zambia.eighty-five dogs were examined and the numbers and types of helminth parasites found were recorded. forty per cent of the dogs were infected with one or more helminth parasites. the most prevalent helminths were the cestodes dipylidium caninum (24.7%) and taenia hydatigena (17.64%). infections were evenly distributed with sex of host. juvenile dogs were more commonly infected with toxocara canis than adults whereas all other helminths were found more in adult dogs.19836649062
a relation between antibody response and acetylcholinesterase activity in dogs and rabbits infected with toxocara canis.a relation between igg antibodies and acetylcholinesterase (ache) activities was observed in the sera of dogs and rabbits infected with toxocara canis (t. canis). no antibodies were found in the sera of dogs' fetuses and newborns, more over their ache levels were lower than the ones registered in the sera of adult dogs. the ache levels of both, the mother dog and the newborn puppies, reached the same level 3 months after delivery. similar results were obtained in the sera of puppies and adult do ...19836649983
the igm antibody activities in relation to the parasitologic status of toxocara canis in dogs.in order to interpret the relation between the igm antibody activities to toxocara canis (t. canis) and the parasitologic status, sera from puppies and adult dogs were measured by the enzyme-linked immunosorbent assay. at the same time, autopsy was performed on these dogs for counting the number of t. canis worms and stool examination was carried out for observing the fertilization of eggs. the rates of infection by t. canis in the dogs decreased with age. the number of worms in the intestines r ...19836649984
experimental ocular toxocara canis and ascaris suum infection: in vivo and in vitro study. 19836659031
detection of specific igm antibodies to toxocaral es antigen: effect of absorption of sera with protein a sepharose.the activity of both the igg and igm antibodies to es antigen from toxocara canis larvae was tested before and after absorption of sera by protein a sepharose 4b (pasb). for this purpose, the elisa technique was applied to the sera from 12 dogs and 6 infants. the effect of absorption of sera by pasb was as follows. the average values before and after absorption in dog sera were 0.11 and 0.02, respectively. the same effect was observed in the infant sera. of the 12 dog sera tested, four had a ele ...19836659738
experimental toxocara canis infection in cynomolgus macaques (macaca fascicularis).visceral larva migrans was produced in 16 cynomolgus macaques (macaca fascicularis) experimentally inoculated with 45,000 embryonated eggs of toxocara canis as a single bolus or in 3 divided doses. the hematologic and serologic changes were similar to those observed in children with visceral toxocara infection. neurologic signs developed in 3 animals and were characterized by ataxia and nystagmus. growth rates were diminished in inoculated animals when compared with the rates in noninoculated co ...19836660626
the effect of toxocara canis infection on the behaviour of mice. 19836660962
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