Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| erythrocyte receptors for malaria merozoites. | 1977 | 413448 | |
| in vitro cultivation and partial purification of plasmodium falciparum antigen suitable for vaccination studies in aotus monkeys. | 1978 | 415127 | |
| selection of increased quinine resistance in plasmodium falciparum in aotus monkeys. | although partial resistance (ri) of plasmodium falciparum to quinine is common in some areas of the world, failure to obtain an initial response (rii or riii) is unusual. furthermore, emergence of quinine resistance during therapy of malaria infections in humans and animals is uncommon. in the current study, exposure of the panama ii strain of p. falciparum in aotus monkeys to subcurative quinine therapy during six serial passages over 6 months resulted in a shift in the quinine responsiveness o ... | 1978 | 415628 |
| abnormal haemoglobins in the sudan savanna of nigeria. iv. malaria, immunoglobulins and antimalarial antibodies in haemoglobin ac individuals. | haemoglobin (hb) ac electrophoretic pattern was found in 0.7% of the population at garki, kano state, northern nigeria, an area where malaria is hyperendemic. twenty-one hb.ac subjects at all ages did not differ from the rest of the population in their frequency or density of plasmodium falciparum, p. malaria or p. ovale infections, nor in their igm concentrations and titres of specific antimalarial antibodies. however, igg levels in hb.ac subjects were frequently above the average of the refere ... | 1979 | 496483 |
| a pocket of controlled malaria in a holoendemic region of west africa. | yekepa, a mining town in northern liberia, has been built entirely since 1960 and now has a population of 16 000 inhabitants including 1500 expatriates. although situated in a holoendemic region with constant human movements in and out of the town, the mining company has succeeded in controlling malaria in yekepa. furthermore, there is a constant threat of the vector in the close surroundings to the town. control is maintained by regular residual insecticide sprayings with ddt, regular larvicidi ... | 1979 | 496484 |
| malarial antibodies in tropical splenomegaly syndrome in papua new guinea. | levels of species and class-specific malarial antibody were studied in 249 new guineans with tropical splenomegaly syndrome (tss) and in 87 control subjects living in the same area. titres of igg and igm antibody to plasmodium falciparum, p. vivax and p. malariae were estimated by indirect immunofluorescence. both ig and igm antibody levels were higher in subjects with tss than in controls; igm titres were highest in those with the greatest splenic enlargement. responses to all three species wer ... | 1977 | 595079 |
| intestinal and blood parasites in the banggai kabupaten, central sulawesi, indonesia. | a survey for blood and intestinal parasites was carried out in the banggai kabupaten central sulawesi, indonesia. a total of 336, stool specimens were obtained from 182 males and 154 females ranging in age from 2 to 90 years. hookworm, trichuris trichiura and ascaris lumbricoides were the most common helminths encountered. schistosoma japonicum was noticeably absent in the population sampled. the following intestingl protozoa were detected: entamoeba coli, e.histolytica, iodamoeba bütschlii, gia ... | 1977 | 607427 |
| parasites of man in remote areas of central and south sulawesi, indonesia. | a biomedical survey was conducted in 10 villages in remote, high mountain valleys of central and south sulawesi, indonesia to learn whether oriental schistosomiasis was endemic and to determine the prevalences of other intestinal parasites, malaria and filariasis in those areas. although persons with oriental schistosomiasis were found in three villages of south sulawesi, follow-up inquiries revealed that these had recently migrated from a known schistosomiasis area in central sulawesi. other in ... | 1977 | 607428 |
| [the question of anhaptoglobinemia in immigrants from west africa (author's transl)]. | studying the plasmatic level and the phenotype of haptoglobine (hp) in 71 west africans living in france, the authors did not record any case of absence of hp (hpo) and did not see any significant correlation between the hp and the duration of stay in france. they conclude that plasmodium falciparum likely does not play any role in the origin of the hpo peculiarity in west african immigrants. | 1978 | 745527 |
| the treatment of malaria. | at least four doses of quinine followed by a single dose of mefloquine or by a single dose of sulfadoxine-pyrimethamine are two highly effective regimens for chloroquine-resistant falciparum malaria. mefloquine alone is valuable in ambulant patients. chloroquine-sensitive falciparum malaria can be treated with a course of chloroquine. vivax and all other types of malaria should be treated with sequential chloroquine and primaquine. quinine, by intravenous infusion, is the most effective drug for ... | 1976 | 764937 |
| receptivity to malaria in europe. | experimental work has confirmed the refractoriness of anopheles atroparvus to tropical strains of plasmodium falciparum to which a. labranchiae may also be refractory. this indicates a lower receptivity to malaria in europe than the existing vector densities and increasing number of parasite carriers would suggest. | 1975 | 764992 |
| thick-smear plasmodium falciparum antigen from in vitro cultures for the indirect fluorescent antibody test. | an important prerequisite for serological studies is the availability of specific antigens with which a high, consistently reproducible degree of test sensitivity can be obtained. in the present study, thick films of p. falciparum antigen were made from in vitro cultures in order to evaluate this antigen in terms of the sensitivity and reproducibility of the indirect fluorescent antibody test, as compared with an antigen prepared from washed infected erythrocytes of aotus trivirgatus monkeys. th ... | 1975 | 764994 |
| observations on the recent incidence of malaria. | 1975 | 765403 | |
| [perinatal transmission of plasmodium falciparum malaria]. | two weeks after leaving nigeria for temperate zones and a few hours after giving birth to twins, a nigerian mother suffered an acute attack of malaria due to plasmodium falciparum accompanied by cerebral, renal and hematolgical complications. both infants were apparently healthy at birth, and no parasites were found on peripheral blood smears. both placentas were macroscopically normal. at two months of age the second infant, a boy, developed non-febrile hemolytic anemia due to plasmodium falci ... | 1975 | 766166 |
| the distribution of enzyme variation in populations of plasmodium falciparum in africa. | isolates of plasmodium falciparum collected from the east and west coasts of tropical africa and also from several inland regions have been examined for electrophoretic forms of the enzymes gpi, ldh and 6pgd. variation within and between isolates was found in the parasite forms of all three enzymes. while not disproving the existence of genetic divisions between p. falciparum populations in africa the distribution of this variation provides no evidence for such a hypothesis. | 1975 | 766317 |
| proceedings: invasion of human red cells by plasmodium falciparum in vitro. | 1975 | 766322 | |
| coagulation studies in falciparum and vivax malaria. | coagulation factors and serum fibrin degradation products (fdp) were studied in 31 cases of acute falciparum malaria with severe complications, 13 cases without severe complications, and 6 cases of vivax malaria. seven of 13 cases of acute falciparum infection with severe complications died and the coagulation studies were markedly changed and there were high levels of serum fdp. the degree of changes in coagulation and serum fdp varied with the severity of the symptoms and signs and there were ... | 1975 | 769173 |
| chloroquine sensitivity of plasmodium falciparum in ethiopia. ii. results of an in vitro test. | field trials were performed in two areas of ethiopia with the rieckmann in vitro test for chloroquine sensitivity of plasmodium falciparum. blood cultures from 82 test subjects showed growth of trophozoites to the schizont stage in control vials. growth in test vials occurred in 21 cultures incubated with chloroquine at concentrations of 0.5 nanomoles or more per ml of blood. in vitro results confirm previous results obtained with an in vivo test. | 1976 | 769570 |
| febrile illnesses resulting in hospital admission: a bacteriological and serological study in jakarta, indonesia. | a study of 741 indonesian patients with fever was carried out in order to determine what serious febrile illnesses are prevalent in jakarta. all patients were hospitalized primarily because of fever and were studied by bacteriological and serological methods. bacteremia due to salmonella typhi (150 cases), s. enteritidis (36 cases), or both (2 cases) was common in both children and adults. one s. enteritidis isolate was chloramphenicol resistant. serological evidence of salmonella infection was ... | 1976 | 769571 |
| single-dose therapy of falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. | patients with naturally acquired chloroquine-resistant falciparum malaria were studied in thailand. the fixed combination of pyrimethamine 75 mg and sulfadoxine 1,500 mg (adult dose) cured 85% of patients with an average pretreatment parasite count of 60,000 per mm(3). the fixed combination of pyrimethamine 50 mg and 800 mg diformyldapsone (dfd) cured 43% of patients with an average pretreatment parasite count of only 17,000 per mm(3). the difference in cure rates was statistically significant ( ... | 1976 | 769572 |
| the seroepidemiology of malaria in middle america. iii. serologic assessment of localized plasmodium falciparum epidemics. | epidemiologic studies were done in two localities, one in panama and one in el salvador, where outbreaks of plasmodium falciparum malaria occurred. the indirect fluorescent antibody (ifa) method was helpful in defining the intensity of the outbreaks, the species of parasite involved, and, through parallel surveys of adjacent localities, the localized character of outbreaks. in escobal, panama 71 (34%) of 211 persons examined were ifa-positive for p. falciparum, although only 1 positive blood fil ... | 1976 | 769573 |
| chloroquine sensitivity of plasmodium falciparum in ethiopia. i. results of an in vivo test. | the in vivo response of plasmodium falciparum to the who single test dose (10 mg/kg body weight) of chloroquine base was examined in ethiopia at four localities where malaria was meso- or hyperendemic. parasitemias cleared by the 3rd day after chloroquine administration in all of the 150 test subjects. no recrudescences were detected during the 6-day or 11-day follow-up periods. the value of the in vivo test was severely limited by the inability to quarantine subjects and follow them for the 28- ... | 1976 | 769574 |
| malarial antibodies measured by the indirect hemagglutination test in west african children. | the indirect hemagglutination test with plasmodium falciparum antigen was used to measure malarial antibodies in filter paper blood specimens from 527 west african children. a slight decline in antibodies was noted in 6- to 8-month-old children wh o had no malaria parasites in their blood smears. children older than 10 months had similar antibody levels regardless of the presence or absence of demonstrated parasites in blood smears. | 1976 | 769576 |
| suppressive activity of mefloquine in sporozoite-induced human malaria. | mefloquine hydrochloride [wr 142,490; alpha-(2-piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol hydrochloride] was tested for suppressive effect on sporozoite-induced malaria in nonimmune volunteers living in an area where malaria is not naturally transmitted. single doses of 250 mg were given at weekly intervals, 500 mg at intervals of 2 weeks and 1,000 mg at intervals of 4 weeks, to men bitten by 10 to 15 mosquitoes heavily infected with a chloroquine- and pyrimethamine-resistant strain ... | 1976 | 769678 |
| jaundice and hepatomegaly in malaria. | 1975 | 770013 | |
| response of p. falciparum infection to chloroquine therapy in some parts of tamil nadu and karnataka states. | 1975 | 770318 | |
| treatment of p. falciparum with chloroquine and primaquine in dharmapuri district, tamil nadu. | 1975 | 770319 | |
| the prevalence of babesia antibodies in nigerians. | 1976 | 770357 | |
| sero-epidemiological surveillance of disappearing malaria in greece. | 1975 | 772232 | |
| chloroquine-resistant falciparum malaria in east kalimantan, indonesia. | following the discovery of four imported chloroquine-resistant p. falciparum infections in the province of yogyakarta (island of java) sensitivity tests were carried out in the province of east kalimantan island of borneo). twenty subjects were given 25 mg. of chloroquine base per kilogram of body weight over three days. two infections were found resistant at the rii level and a third at the ri level with early recrudescence on day 7. in the other 17 cases followed up to day 21, six were found a ... | 1976 | 772235 |
| [letter: a recent case of human babesiasis]. | 1976 | 772600 | |
| histamine changes in plasmodium falciparum malaria. | histamine, serum complement factor 3 (c'3) and platelets were studied in 33 plasmodium falciparum patients. elevation of histamine level in the blood was found during acute infection but was more marked in the group of patients with systemic complications. a correlation between histamine changes, clinical complications, reduction of c'3 and degree of thrombocytopenia was observed. the possible role of histamine in the development of complications in p. falciparum infection and the possible relea ... | 1976 | 772896 |
| a new look at the protection of hemoglobin as and ac genotypes against plasmodium falciparum infection: a census tract approach. | a total of 4,097 randomly selected children under 5 years in accra, ghana were investigated for hb type, malarial parasite species, and parasite density. even though malarial infection rates in this metropolitan population were lower as compared to holoendemic areas, the differential survival of hb s carriers was confirmed. in addition, similar but less pronounced survival effects were seen in hb c heterozygotes. hb s carriers had the highest infection rates. more females than males were infecte ... | 1976 | 773175 |
| glucose-6-phosphate and 6-phosphogluconate dehydrogenase activities human erythrocytes infected with plasmodium falciparum. | 1976 | 773316 | |
| editorial: new look at malaria. | 1976 | 773496 | |
| quinine disposition during malaria and during induced fever. | quinine disposition was studied in 5 subjects before and during an experimentally induced infection with a chloroquine-resistant strain of plasmodium falciparum and in 2 individuals before and during artificially induced fever. plasma quinine levels were determined by both a benzene extraction method (qb), which measures principally unmetabolized quinine, and a metaphosphoric acid precipitation method (qmpa), which measures quinine and quinine metabolites. the ratio qb/qmpa in plasma was used to ... | 1976 | 773582 |
| chloroquine-resistant falciparum malaria from irian jaya (indonesian new guinea). | a strain of plasmodium falciparum, transmitted in irian jaya (indonesian new guinea) was isolated in 1974 and sent to the university of maryland for characterization in nonimmune volunteers. at maryland the indonesia (whit.) strain, as it has been designated, was transmitted to colonized anopheles stephensi. prophylactically, it was not suppressed by proguanil hydrochloride 100 mg. daily. curatively, parasitaemia was not cleared by treatment with 1-5 g. (base) in three days of chloroquine or amo ... | 1976 | 775119 |
| [malaria prophylaxis]. | 1976 | 775347 | |
| increased frequency of chloroquine resistant p. falciparum on a rubber estate in peninsular malaysia during two years of systematic chloroquine treatment. | chloroquine pressure was applied over a 22 month period on a somewhat isolated, malarious rubber estate by examination of residents at 4-week intervals and treatment of parasitaemias with chloroquine. during this time the monthly attack rate for p. falciparum rose four-fold to an average of nearly 18% per month, while that of p. vivax remained relatively constant at about 8%. eight in vivo chloroquine resistance studies, which allowed both detection of late recrudescing r-i resistance and estima ... | 1975 | 775652 |
| malaria guidelines: cdc recommended treatment schedules, 1974. | 1976 | 776514 | |
| [letter: transplacental passage of soluble plasmodial antigens. induction of a specific immune tolerance?]. | 1976 | 778794 | |
| [malarial encephalopathy and disseminated intravascular coagulation (author's transl)]. | clinical and anatomical studies of a case of malarial encephalopathy are described in a 51 year old man. in view of the typical symptomatology it was important to ascertain an period even brief of stay in an endemic area. only when this was confirmed the appropriate investigations could be planned (in thic case thick blood drop test) to identify the parassite. the physiopathological mechanisms through which the malarial infection causes the parenchymal lesions are considered. such lesions accord ... | 1975 | 778999 |
| persistence and recurrence of s-antigen in plasmodium falciparum infections in man. | the persistence of heat stable malarial antigens (s-antigens) in the sera of gambian children following treatment for severe plasmodium falciparum infections was investigated. in most cases s-antigens ceased to be demonstrable within 7 days but in some they were detected for several weeks and their persistence correlated with both the density of parasitaemia and the antigen titre observed before treatment. an exponential loss of circulating antigen was, in the majority of individuals, accelerate ... | 1975 | 779155 |
| letter: response of ethiopian strains of plasmodium falciparum to amodiaquine. | 1975 | 779158 | |
| complement and malaria. | 1976 | 779685 | |
| [50 cases of acute malaria: symptomatic study, especially cardiac]. | the authors have studied 50 records of patients who had presented an acute attack of p. falciparum malaria. both sexes were equally implied. young people were predominant. the distribution of cases was about the same in the whole year. the fever decreases on the second day and increases on the third day (300/0). among the classical signs: relative rarity of hepatomegalia (100/0), splenomegalia (10 0/0), jaundice (140/0), nervous symptoms (100/0). vomiting is rather frequent (30 0/0). from the ca ... | 1975 | 779991 |
| [evaluation of plasmodium falciparum antigen of human origin using indirect immunofluorescence reaction in malaria]. | the authors point out the use of p. falciparum antigens from man in the malaria ifa test. in malaria areas it is very easy to find them and although they are "coated" by antibodies they are quite valuable in significant titers. the use of p. falciparum from man is therefore very interesting for malaria diagnosis in non endemic areas and very useful for malaria surveys in endemic areas. | 1975 | 779993 |
| peripheral lymphocyte subpopulations in human falciparum malaria. | the concentration of circulating t, b, and 'null' lymphocytes was determined in thirty children and three adults with plasmodium falciparum infections in west africa. during infection, both percentage as well as concentration of t cells were decreased as compared to levels following treatment. the percentage but not concentration of b cells was increased. both percentage and concentration of 'null' cells were increased in malaria. patients with splenomegaly had the most severe alterations in t-c ... | 1976 | 780013 |
| malaria eradication and control from a global standpoint. | 1976 | 781250 | |
| human malaria parasites in continuous culture. | plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees c in rpmi 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and low oxygen (1 or 5 percent). the original parasite material, derived from an infected aotus trivirgatus monkey, was diluted more than 100 million times by the addition of human erythrocytes at 3- or 4-day intervals. the parasites continued to reproduce in their normal asexual cycle of approxima ... | 1976 | 781840 |
| malaria - the mime. recent lessons from a group of civilian travellers. | clinical data on 24 civilian patients hospitalized for malaria in the new york hospital were analyzed. of 16 patients infected with plasmodium falciparum, 14 acquired the disease in west africa. only three of the 24 had taken recommended courses of prophylaxis. diagnosis was invariably, and often dangerously, delayed because physicians often made diagnoses of viral syndromes or used antibiotics; only one patient had a blood smear taken by a personal physician. although all patients had fever and ... | 1976 | 782238 |
| malaria at the hospital for sick children, toronto. | the number of immigrants to canada from countries where malaria is endemic increased sevenfold between 1964 and 1974. from january 1973 through july 1975, 15 cases of malaria were treated at the hospital for sick children, toronto. the only symptom common to all patients was fever, and it was not always cyclic. for any child with a fever of unknown cause who has been in a region where malaria is endemic within the previous 6 months, a blood smear should be examined for parasites. if the smear is ... | 1976 | 782677 |
| symptoms and signs of malaria. | in addition to asking their patients about recent foreign travel, canadian doctors need to be aware of what features to ask about in considering imported illnesses. of these illnesses, malaria is one of the most common and serious. because of its cerebral renal, pulmonary and intestinal complications, falciparum malaria must be distinguished from non-falciparum forms. anyone with a fever who has arrived recently from an endemic area should be tested for malaria. in addition, headache, malaise, m ... | 1976 | 782678 |
| lung uptake of 99mtc-sulfur colloid in falciparum malaria: case report. | increased lung uptake of 99mtc-sulfur colloid was seen during liver scanning in a patient with falciparum malaria. this finding was due to the enhanced activity of the phagocytic cells of the reticuloendothelial system in the liver, spleen, and lung found in human and experimental malaria. similar findings in other clinical situations and the relevant literature are reviewed. | 1976 | 784917 |
| studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in peninsular malaysia. | in vivo chloroquine resistance surveys, which allowed for detection of late recrudescing ri resistance, were conducted in three regions of peninsular malaysia, which were previously not recognized as having appreciable drug resistance. among the 485 plasmodium falciparum infections tested resistance rates ranged locally from 20% to 67% in those with parasitaemias over 1,000 per mm3, and 5% to 59% in all parasitaemias. the region found to have the most serious resistance was western pahang. in on ... | 1976 | 785725 |
| two cases of malaria presenting with psychiatric symptoms. | mood and behavior disorder may appear either due to primary psychiatric disorder or may signify an underlying, frequently undetected, physical pathology. two instances of malaria falciparum presenting with psychosocial symptomatology are described. | 1976 | 786382 |
| a study of the clinical features of malaria in rhodesia. part iii. african children. | 1976 | 786460 | |
| lack of a circadian rhythm in the ability of the gametocytes of plasmodium falciparum to infect anopheles gambiae. | 1976 | 786919 | |
| method to test inhibitory antibodies in human sera to wild populations of plasmodium falciparum. | 1976 | 787801 | |
| [the treatment of severe tropical malaria]. | 1976 | 787812 | |
| studies on the infectivity of tropical african strains of plasmodium falciparum to some southern european vectors of malaria. | preliminary experiments in garki, nigeria, with a. atroparvus from italy have shown a refractoriness to infection with the local strain of p. falciparum. comparative studies involving a. labranchiae and two strains of a. atroparvus, all from italy, and one local strain of a. gambiae species b, were carried out at kismu, kenya. while oocysts developed in 77% of a. gambiae and, from day 14 onwards, 100% of the oocyst positive mosquitos had sporozoites in the salivary glands, oocysts were seen in o ... | 1975 | 787897 |
| parasitic infections in humans in west kalimantan (borneo), indonesia. | a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ... | 1976 | 788263 |
| malaria threat to the seychelles. | 1976 | 788847 | |
| [a surprising cause of error in platelet counting: intra-erythrocyte trophozoites]. | 1976 | 790317 | |
| [comparative evaluation of three antigens for the serodiagnosis of malaria (author's transl)]. | 1976 | 790380 | |
| vaccination against plasmodium falciparum: a negative result. | 1976 | 790673 | |
| the blood groups, serum groups, red-cell isoenzymes and haemoglobins of the sandawe and nyaturu of tanzania. | blood specimens from members of the click-speaking sandawe tribe of tanzania and of the adjacent bantu-speaking nyaturu tribe have been tested for antigens of 11 blood group systems, for variants of 3 plasma-protein systems and 9 red-cell-enzyme systems, for haemoglobin variants. the results are tabulated and gene frequencies computed. for most systems, the frequencies in the two tribes are similar to one another and, in so far as data are available, similar to the neighbouring bantu-speaking tr ... | 1976 | 791061 |
| chemoprophylaxis of malaria. | 1976 | 791446 | |
| preliminary studies on the response of plasmodium falciparum to chloroquine in the philippines, with the in vitro technique. | previous investigations had shown that resistance to standard regimens of chloroquine occurred in some cases of falciparum infection in the philippines. more extensive investigations into this phenomenon were planned by the malaria eradication service, by means of the in vitro technique developed by rieckmann, in order to determine both the distribution of resistant strains throughout the country and their local incidence. before these studies were undertaken, a series of observations were made ... | 1976 | 791531 |
| chloroquine-resistant falciparum malaria in papua new guinea. | 1976 | 792661 | |
| nursing care study: malaria. | 1976 | 792822 | |
| a marked reduction in the incidence of cold haemagglutinin in plasmodium falciparum malaria. | a survey of cold haemagglutinin using the normal and tyrpsinized group o red blood cells was performed in 101 normal individuals, 139 individuals with plasmodium falciparum malaria, 115 individuals with various infections other than malaria and 46 cases of auto-immune haemolytic anaemia. a marked reduction in the incidence of cold haemagglutinin reacting with the normal group o red blood cell was observed in cases of p. falciparum with parasitaemia higher than 100 000/mm3. although this was also ... | 1976 | 793545 |
| clinical and laboratory presentation of malaria: an analysis of one thousand subjects with malaria parasitaemia. | in the context of this study the ethnic origin of the patients revealed no noteworthy difference in the clinical reaction to the parasite; neither did age or sex of the patients. any minor differences whcih appeared in length of history before seeking treatment and frequency of repeat attacks were more a reflection of the cultural pattern of response to illness (i.e. resort to traditional medicines) and the distance between the patient's home and the doctor rather than any altered response on th ... | 1976 | 794512 |
| jaundice and hepatomegaly in primary malaria. | the hepatic manifestations were studied in 65 patients having uncomplicated primary attacks of vivax and falciparum malaria. hepatomegaly due to a "non-specific reactive hepatitis" occurred in 57% of cases. jaundice occurred in 15% of patients and was invariably associated with hepatomegaly. the clinical syndromes of jaundice and hepatomegaly in uncomplicated primary attacks of malaria have to be distinguished from those related to disorders like viral hepatitis, hepatic amoebiasis, typhoid hepa ... | 1976 | 794514 |
| plasmodium falciparum gametocytogenesis in vitro. | 1976 | 794731 | |
| aspects of tropical paediatrics. | malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. the most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. reasons for this trend are discussed. efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in s.e. asia ... | 1976 | 795103 |
| infectivity of falciparum malaria patients for anopheline mosquitoes before and after chloroquine treatment. | the infectivity of 25 falciparum malaria patients for anopheles balabacensis and anopheles minimus, before and after chloroquine therapy, was studied in central thailand. the proportion of patients infective for these mosquitoes was not affected by the administration of chloroquine, however, an elevation was observed in the median values for the numbers of oocysts on the guts of the a. balabacensis, but not the a. minimus, fed on infective patients after initiation of treatment. | 1976 | 795104 |
| precipitating antibody response to malarial s-antigens. | the gel diffusion test has been used to detect antibodies to malarial s-antigens. sera were obtained from entire gambian village communities, from young children with acute p. falciparum malaria, from children convalescent from such infections and from immune adults. in community studies, small selections of s-antigens detected antibody frequently in sera from older persons but rarely in sera from young children. larger panels of antigens detected antibodies in sera from half of 50 malarious chi ... | 1976 | 795105 |
| gametocytes of plasmodium falciparum: phagocytosis by leucocytes in vivo and in vitro. | phagocytosis of the extracellular gametocytes of plasmodium falciparum has been demonstrated in vitro, and in vivo in the bloodmeal within the mosquito midgut. up to 84% of the gametocytes were ingested within two hours in vitro, compared to 7% in the same period in the mosquito gut. | 1976 | 795106 |
| evaluation of two phenanthrenemethanols for antimalarial activity in man: wr 122,455 and wr 171,669. | two phenanthrenemethanols, wr 122,455 and wr 171,669, were tested in man for oral tolerance, toxicity, and efficacy against plasmodium falciparum. in healthy subjects, gastrointestinal symptoms limited single-day dosage of wr 122,455 to 800 mg and wr 171,669 to 1,260 mg. no laboratory abnormalities phototoxicity, or gastrointestinal blood loss were noted in the subjects receiving these drugs. in subjects infected with malaria, wr 122,455 cleared parasitemia when given for 1 day in doses from 440 ... | 1976 | 795309 |
| an evaluation of malaria fluorescent antibody patterns in several remote island populations of the new hebrides, solomons, western carolines, and new guinea. | from a representative sampling of several remote populations living on the banks and torres islands (new hebrides), the eastern and southern districts of the solomon islands, the western caroline islands (u.s. pacific trust territory), west new guinea (indonesia), and papua new guinea, 752 sera were examined for fluorescent antibodies to the four species of human malaria, and the results were compared to already published parasite survey data based on blood smears and medical examinations. antib ... | 1976 | 795310 |
| [splenic infarction in primary plasmodium falciparum infection]. | 1976 | 795334 | |
| treatment of p. falciparum infection with chloroquine and primaquine in salem and sathyamangalam towns of tamil nadu. | 1976 | 795769 | |
| a comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in peninsular malaysia. | 1976 | 796479 | |
| investigation of imported malaria cases in japan in 1972-1974. | 1976 | 796480 | |
| chloroquine-resistant falciparum malaria acquired in papua new guinea. | 1976 | 796648 | |
| additional foci of chloroquine-resistant falciparum malaria in east kalimantan and west irian, indonesia. | 1976 | 797072 | |
| [human and animal parasitic diseases in the new hebrides]. | new-hebrides condominium, an archipelago in the south pacific, is a country with a special socio-political environment, due to the duality of its french-british regime. this state of affairs is felt in all areas including public health, where we find french, british and condominial personnel. the pathology of parasitic diseases is essentially tropical with a strong predominance of paludism, at times fatal, and intestinal nematodes; however we rarely find amibiasis or human hydatid disease. stron ... | 1976 | 797480 |
| [chemotherapy of acute malaria attacks in patients returning from tropical and subtropical countries (author's transl)]. | the number of primary malaria attacks caused by imported infections notified in the federal republic of germany during the period of 1963 through 1975 has increased five fold from 30 to 154 per year. the total number of deaths in the same period was 55. this gave rise to outline again the established methods of chemotherapy and their parasitological basis. the chloroquine resistance of p. falciparum strains is discussed. no causal relationship exists between drug resistance and the fatalities by ... | 1976 | 797656 |
| study on inhalation therapy by an indigenous compound on p. vivax and p. falciparum infections--a preliminary communication. | 1976 | 797658 | |
| malaria. | 1976 | 799232 | |
| [drug resistance in malaria parasites. 1. the nature of resistance, its distribution and epidemiological implications (review of the literature)]. | 1976 | 799239 | |
| [drug resistance of malaria parasites. 2. clinical aspects, drug treatment and prevention of drug-resistant malaria]. | 1976 | 799242 | |
| acute cerebellar syndrome in falciparum malaria. | 1976 | 799540 | |
| [fluorescent antibodies in the cerebrospinal fluid and serum of patients suspected of cerebral malaria caused by plasmodium falciparum]. | the authors report the results of indirect immunofluorescent technique used for detecting malarial antibodies in the cerebrospinal fluid and serum of 126 african patients suspected of cerebral malaria from infection with plasmodium falciparum. almost all of them were less than 15 years old and were living in urban unstable hypoendemic areas. malarial antibodies, mainly igg, were found in about 25 0/0 of cerebrospinal fluid samples, whether the patients were admitted for malaria or for any other ... | 1976 | 799542 |
| heparin in the treatment of cerebral malaria (a preliminary report). | 1976 | 800248 | |
| chloroquine resistance trials in papua new guinea. 1. maprik and popondetta areas. | the response of plasmodium falciparum infections to a standard weight related dose of chloroquine using the w.h.o. extended field test was investigated in the maprik and popondetta areas of papus new guinea. fourteen cases of p. falciparum in maprik and 12 cases at popondetta were followed daily for seven days and weekly for a further three weeks after receiving 25 mg/kg of chloroquine over three days. all subjects responded well, the parasitaemias cleared in all cases by the fourth day after in ... | 1976 | 800313 |
| estimation of incidence and recovery rates of plasmodium falciparum parasitaemia from longitudinal data. | a method is described of estimating the malaria incidence rate ĥ and the recovery rate r from longitudinal data. the method is based on the assumption that the phenomenon of patent parasitaemia can be represented by a reversible two-state catalytic model; it is applicable to all problems that can be represented by such a model.the method was applied to data on falciparum malaria from the west african savanna and the findings suggested that immunity increases the rate of recovery from patent para ... | 1976 | 800968 |
| malarial nehprosis. | 1976 | 801295 | |
| malaria. | 1975 | 802822 |