Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| trypanosoma cruzi in the cerebrospinal fluid during the acute stage of chagas' disease. | 1978 | 415236 | |
| antibody dependent cell-mediated cytotoxicity against trypanosoma cruzi. | this paper describes in vitro antibody dependent cytotoxicity against trypanosoma cruzi epimastigotes by normal mouse splenic lymphocytes. cytotoxicity was expressed as the percentage reduction in the number of motile parasites upon incubation with lymphocytes at 37 degrees c in a defined medium. failure of the non-motile parasites to regain motility and their ensuing degeneration of 28 degrees c in liver infusion tryptose (lit) medium confirmed loss of motility as a criterion of cytotoxicity. i ... | 1977 | 415286 |
| [study of plasma lipoprotein lipase activity in chronic chagas' disease]. | 2006 | 415346 | |
| recovery from heart norepinephrine depletion in experimental chagas' disease. | norepinephrine (ne) was assayed fluorimetrically in the hearts of rats killed at different periods after inoculation with the y strain of trypanosoma cruzi. the levels of cardiac ne which, as reported previously, were not measurable 18, 22, and 32 days after inoculation became detectable at day 48. at day 70 these levels were around 50% of the control values and at day 97 normal values were attained in most animals. these results strongly suggest that sympathetic nerve fibers are destroyed in th ... | 1978 | 415626 |
| immunization of mice against infection with trypanosoma cruzi. cross-immunization between five strains of the parasite using freeze-thawed vaccines containing epimastigotes of up to five strains. | 1978 | 415993 | |
| [direct agglutination reaction for the diagnosis of chronic chagas disease (author's transl)]. | 1978 | 416477 | |
| the effect of acute infection by trypanosoma cruzi upon the response of mice to sheep erythrocytes. | 1977 | 416482 | |
| [experimental study on the therapeutic action of ro 7-1051 on infections caused by different strains of trypanosoma cruzi]. | 1977 | 416483 | |
| the primary isolation by haemoculture of trypanosoma (schizotrypanum) cruzi from animals and from man. | 1978 | 416524 | |
| comparative xenodiagnosis with three triatomine species of different hosts with natural and experimental chronic infections with trypanosoma (schizotrypanum) cruzi. | simultaneous xenodiagnosis was made of 29 patients with chronic chagas's disease, six naturally infected opossums (didelphis azarae) and of a rhesus monkey with an experimental chronic infection with trypanosoma (schizotrypanum) cruzi (peru strain). patients and opossums were from an endemic area in the state of bahia, brazil, where panstrongylus megistus is the sole domiciliary vector of the disease to man. various instars of p. megistus triatoma infestans and rhodnius prolixus were used. the p ... | 1978 | 416525 |
| [spontaneous infection of marmoset-monkeys (sanguinus oedipus) with a trypanosoma cruzi-like-strain, springer 1975. isolation and identification (author's transl)]. | a trypanosoma cruzi-like strain was isolated from marmoset monkeys originating from columbia. the frequency of affected monkeys was up to 32.7%. the parasite density was 10-40 trypomastigote forms per mililiter. monkeys, rats, mice and other small rodentia were found to be susceptible. clinical symptoms or histopathological findings could not be acertained with these trypanosomes even after a 2 1/2 year observation period. the strain behaved as an apathogen in experimental animals. the parasitae ... | 1977 | 416623 |
| [evaluation of the efficacy of nifurtimox in chronic human chagasic infection by using xenodiagnosis (author's transl)]. | 1977 | 416834 | |
| [diurnal and nocturnal positivity of the xenodiagnosis in a patient with chronic chagasic infection and permanent parasitemia (author's transl)]. | 1977 | 416835 | |
| isozymic heterogeneity of trypanosoma cruzi in the first autochthonous patients with chagas' disease in amazonian brazil. | 1978 | 417267 | |
| the effect of an immune rna (rnai) against trypanosoma cruzi infection in mice. | immune ribonucleic acid (rnai) was extracted with phenol from the spleen of mice immunized with the avirulent pf strain of trypanosoma cruzi. these preparations were able to induce immunocompetent cells to answer as a secondary response to later challenges with the virulent y strain of the same parasite. the preparations of rnai were"immunogenic" and free of proteins. the rnai preparations were sensitive to pancreatic rnaase and lost their immune effect when pretreated with this enzyme. the inje ... | 1978 | 417440 |
| [early immunological aspects in rats infected by trypanosoma cruzi. i. agglutination and immunofluorescence tests with antigen of trypomastigotes recovered in successive days of the infection (author's transl)]. | from rats infected with the y strain of t. cruzi trypomastigotes were recovered in successive days to be used in agglutination tests (at) and in direct immunofluorescence tests (dit). titres obtained in at reached 1/640 with trypomastigotes in the fourth and fifth days, decreased to 1/160 in the sixth day and were negative in the seventh day; in the tenth day the titers were again up to 1/40 and reached 1/320 in the eleventh day. the dit were negative with trypomastigotes in the fourth and fifth ... | 1978 | 418466 |
| presence of immunoglobulins on the surface of bloodstream trypanosoma cruzi. capping during differentiation in culture. | 1977 | 418490 | |
| [disorder of the urinary concentration mechanism in patients with a chronic form of chagas disease]. | 2006 | 418493 | |
| effect of sex of mice in relation to their response to immunization with vaccines prepared from trypanosoma cruzi. | 1978 | 418539 | |
| mode of action of the 2-nitroimidazole derivative benznidazole. | using cultures of trypanosoma cruzi cells in a liquid medium, the mode of action of the 2-nitroimidazole derivative benznidazole was examined. benznidazole inhibits protein synthesis and rna synthesis in t. cruzy. the dna synthesis is only slightly decreased and no effect on the aerobic respiration of t. cruzi was observed. | 1978 | 418744 |
| the effect of nifurtimox on experimental infections with trypanosomatidae other than trypanosoma cruzi. | the influence of nifurtimox on trypanosoma brucei, t. congolense, t. equinum, t. equiperdum, t. evansi, t. gambiense, t. lewisi, t. rhodesiense, t. vivax, leishmania donovani and l. tropica has been studied in animals and in vitro. the drug was active against all of them but there are considerable differences in sensitivity of the various species as well as of different strains of t. rhodesiense. for the treatment of t. rhodesiense a single high dosage was more efficient than the same dose divid ... | 1979 | 506553 |
| mortality and other parameters of concomitant infections in albino mice: the schistosoma-toxoplasma model. | inocula of s. mansoni and t. gondii well tolerated by albino mice when given singly, were given concomitantly to groups of animals. few notable effects were observed when toxoplasmosis preceded schistosomiasis, but the s. mansoni leads to t. gondii model, with an interval of 59 days between infections, led to massive mortality, great weight loss and a striking splenomegaly. these findings are very similar to data from previous work on the s. mansoni leads to trypanosoma cruzi model. the authors ... | 1977 | 610025 |
| [influence of the cryopreservation at nitrogen temperature on the vaccinic ability of the "pf" strain of trypanosoma cruzi (author's transl)]. | the cryopeservation of the "pf" strain of t. cruzi at -196 degree c has not changed its effectiveness in protecting mice against a posterior infection with a virulent trypanosoma cruzi strain. the cryopeservation technique utilized seems to be efficient and of practical and rapid examination. | 1978 | 684265 |
| regional variations in calculated diastolic wall stress in rat left ventricle. | principal radii of curvature and wall thickness were measured at the apex and three other loci on the free wall of the left ventricle in 16 rat hearts that had been fixed at end-diastolic pressure. the law of laplace was applied to calculate the mean tensile stress at each locus. no significant variation was found among the nonapical loci, but apical stress was approximately twice the stress calculated for any nonapical locus. the higher stresses that must be borne by the apex may be a predispos ... | 1978 | 686193 |
| [achalasia caused by infiltrating carcinoma of the esophagus. clinical case and physiopathological considerations]. | a case of symptomatic esophageal achalasia due to a slowly growing neoplastic infiltration of the esophageal wall by a mammary indifferentiated carcinoma operated ten years before is presented. at admission, the clinical history and the endoscopic appearance of the esophageal lumen and mucosa led to the diagnosis of idiopathic achalasia, while the esophageal manometry showed a rather long high pressure zone (6--8 cm), which did not relax with deglutition. barium study confirmed the length of the ... | 1978 | 692894 |
| community participation in health activities in an amazon community of brazil. | this article describes community participation in a comprehensive eight-year health program at porto nacional, a town in brazils amazon region. the authors discuss various techniques employed to encourage community participation, indicate methods used to resolve low-key conflicts in a positive manner, describe the major contributions made by community participation in this program, and present a number of conclusions considered applicable to other communities in this part of brazil. | 1978 | 698459 |
| serum ige levels in amoebiasis. | elevated levels of serum immunoglobulin e (ige) are found in many parasitic diseases. in order to determine the influence of entamoeba histolytica on ige levels of clinically symptomatic patients with intestinal amoebiasis, a controlled study was performed. there was no difference between the serum ige values from brazilian patients with amoebiasis and those from age-, race- and sex-matched normal brazilian controls. based also on our previous similar studies on giardiasis and chagas' disease, w ... | 1978 | 709800 |
| mechanisms of natural resistance to trypanosomal infection. role of complement in avian resistance to trypanosoma cruzi infection. | the natural resistance of chickens to trypanosoma curzi infection and the capacity of their sera to lyse blood (trypomastigote) forms of the parasite in vitro were found to be complement-dependent phenomena. parasites given intravenously to decomplemented chickens were detectable in their bloodstream for at least 24 h post-infection, whereas in untreated animals they became undetectable after 1 min (and destroyed flagellates were observed). one millilitre of serum had the capacity to lyse as man ... | 1976 | 765264 |
| topographical differences in the distribution of surface coat components and intramembrane particles. a cytochemical and freeze-fracture study in culture forms of trypanosoma cruzi. | a regional specialization of the cell surface of t. cruzi culture forms was found at the cytostome as a localized thick surface coat rich in carbohydrate-containing components. the prominent surface coat was located over a region of the plasma membrane where intramembranous particles were exceedingly low in number. in turn, the particle-poor region was related to specialized submembrane fibrils not present under other regions of the plasma membrane. the cystostome region provides a striking exam ... | 1976 | 770483 |
| use of 125i-labelled albumin for the detection and measurement of delayed-hypersensitivity reactions in the mouse. | accumulation of 125i-labelled albumin in the mouse hind foot has been used to measure reactions of delayed hypersensitivity in the mouse. the assay is technically simple and permits use of groups of 10 or more animals. its sensitivity and reproducibility have been demonstrated by comparing sensitized with non-sensitized animals in two antigen systems (p.p.d. and an extract of trypanosoma cruzi). | 1976 | 774994 |
| trypanosoma cruzi: mechanism of entry and intracellular fate in mammalian cells. | the mode of entry and intracellular fate of epimastigotes and trypomastigotes of trypanosoma cruzi in cultured cells was studied. electron microscopic observations indicated the uptake by phagocytosis of both forms into mouse peritoneal macrophages and of trypomastigotes and transition forms into other cultured cell types. in each instance the organisms were initially surrounded by a plasma membrane-derived phagosome. trypsin and chymotrypsin treatment of the macrophages completely abolished att ... | 1976 | 775012 |
| strain-dependent thermosensitivity influencing intracellular differentiation of trypanosoma cruzi in cell culture. | temperature strongly influenced morphogenesis of intracellular trypomastigotes in cell culture infected with 2 different strains of t. cruzi. with the gilmar strain the amastigote-to-trypomastigote differentiation readily occurred at 33 and 37 c, whereas the cl strain differentiation took place at 33c but was inhibited at 37 c. the possiblity of this selective thermosensitivity resulting from mutational adaptation of the parasite is discussed. | 1976 | 775065 |
| comparative kinetics of arginine and lysine transport by epimastigotes and trypomastigotes from two strains of trypanosoma cruzi. | three-day-old cultures of y and mr strains of trypanosoma cruzi ahd a higher rate of lysine and arginine uptake than 10-day cultures. amino acid uptake by cells of the mr strain was consistently higher than that of the y strain. flagellates separated on deae-cellulose columns have normal structure, motility, and infectivity; they have the higher rates of lysine and arginine uptake than the original 3- and 10-day cultures. in addition passage through deae-cellulose columns modified the kinetic be ... | 1976 | 775066 |
| trypanosoma cruzi: effects of rhodnius prolixus extracts on in vitro development. | 1976 | 775590 | |
| ultrastructural observations of trypanosoma cruzi in a liquid medium: the kinetoplast-mitochondrion in division forms. | 1976 | 776884 | |
| a simple monophasic medium for axenic culture of hemoflagellates. | an inexpensive, easily prepared monophasic medium which supports continuous culture of leishmania donovanì (approximately 4 x 10(7) cells/ml/day 5) and l. tarentolae (approximately 3.5 x 10(7) cells/ml/day 5) promastigotes has been developed. this medium, designated ho-mem, is a modified eagle's minimal essential medium with spinner's salts and 10% fetal calf serum. epimastigotes of trypanosoma cruzi, costa rica strain, also grew well in ho-mem (approximately 2 x 10(7) cells/ml/day 5) but cells ... | 1976 | 778371 |
| circulating antibodies in cutaneous leishmaniasis: their detection by immunofluorescence. | with the use of an indirect fluorescent antibody (ifa) test and freeze-dried antigens, circulating antibody titres of 1 in 100 or above to leishmania tropica leptomonad forms were detected in 66-6% and 76-2% of 18 patients with active and 21 patients with healed cutaneous leishmaniasis, respectively. cross-reactivity was observed with l. donovani and trypanosoma cruzi antigens. five out of 15 patients with active pulmonary tuberculosis had antibodies to l. tropica major, suggesting a possible cr ... | 1975 | 779154 |
| a fluorescent character distinguishing strains of trypanosoma (schizotrypanum) cruzi isolated from animals. | 1975 | 779157 | |
| a lipopeptidophosphoglycan from trypanosoma cruzi (epimastigota). isolation, purification and carbohydrate composition. | a lipopeptidophosphoglycan was extracted from epimastigote forms of trypanosoma cruzi by phenol (44%) treatment of sonicated cells. the substance was purified from other glycoproteins and nucleic acid as follows: ethanol fractionation. bio-gell p-150 column chromatography in the presence of 0.1% sodium dodecyl sulfate, extraction with chloroform/methanol/water (10 : 10 : 3) and precipitation of the pure compound by methanol. the substance migrated as a single band in sodium dodecyl sulfate-polya ... | 1976 | 782545 |
| localization of peroxidase activity in trypanosoma cruzi microbodies. | electron microscopic observation of trypanosoma cruzi epimastigotes reveals the presence of microbody-like structures (microperoxisomes) in which 3,3'-diaminobenzidine (dab) is peroxidized to electron-opaque material. the role of peroxidase in dab peroxidation is supported by the enzyme demonstration in disrupted epimastigotes and the microbody-containing cell fractions. | 1976 | 782907 |
| cytochrome p-450 and drug metabolism in trypanosoma cruzi: effects of phenobarbital. | the epimastigotes of trypanosoma cruzi hydroxylate drugs at substantial rates. the activity, which is of the mixed-function oxidase type, is increased by phenobarbital and is inhibited by co, skf 525-a, and metyrapone. the hydroxylation is paralleled by increases in free and membrane-bound ribosomes. | 1976 | 785602 |
| species of the subgenus schizotrypanum other than trypanosoma cruzi and their potential usefulness in the laboratory. | 1976 | 785723 | |
| letter: trypanosomiasis cruzi in mice with trichinosis. | 1976 | 785726 | |
| a simple method of tracking mammals and locating triatomine vectors of trypanosoma cruzi in amazonian forest. | a simple method of tracking mammals from capture points to their refuges was developed to study trypanosoma cruzi reservoir-vector associations in belém forest. a device containing a spool of fine line was carried by released mammals so that the line unwound under minimum tension as the animal proceeded and could be followed the day after release. twenty-three triatomine bugs of five species were found with 3 of 15 mammals retrieved. | 1976 | 786052 |
| uptake of fetal proteins by trypanosoma cruzi immunofluorescence and ultrastructural studies. | 1976 | 786918 | |
| electron microscopic study of trypanosoma cruzi periplast in tissue cultures. i. number and arrangement of the peripheral microtubules in the various forms of the parasite's life cycle. | in an electron microscopic study, counts of peripheral microtubules were made in spheromastigotes and trypomastigotes in tissue cultures of embryonic heart muscle cells. in interphase spheromastigotes there were, at the level of the nucleus, approximately 114 microtubules; in dividing forms, there were approximately 222. in trypomastigotes, the number of microtubules varied according to the level of the section--there were fewer than 40 tubules in the pointed ends of an organism, while in the ce ... | 1976 | 787513 |
| [effects of gamma rays on trypanosoma cruzi. ii antibodies in mice inoculated with culture forms]. | 1976 | 788112 | |
| proline metabolism in trypanosoma cruzi epimastigotes. | 1976 | 789007 | |
| [vaccination with live, non-virulent trypanosoma cruzi vaccine in man. a 5-year follow up study the 1st 2 cases]. | 1976 | 790483 | |
| glucose metabolism, growth and differentiation of trypanocoma cruzi. | 1976 | 790488 | |
| patterns of development of trypanosoma cruzi in the embryonated chicken egg. | blood forms of four strains of trypanosoma cruzi were inoculated on the chorioallantois or intra-yolk sac in seven to nine day embryonated chicken eggs which were reincubated thereafter at 37-5-39-0 degrees c or at 32-34 degrees c. there were no significant differences between strains when total rates of infected eggs were compared. however, the highest proportions of positives, for every strain, were found among eggs inoculated into the yolk sac and reincubated in the lower temperature range. t ... | 1976 | 793546 |
| the enzymic hydrolysis of acetyl-coenzyme a by trypanosomatid flagellates. | 1976 | 793894 | |
| loss of infectivity of mycobacterial and protozoal exoplasmic parasites after exposure in vitro to the polyenzymic cocktail 'pigo'. | 1976 | 793902 | |
| demonstration of kinetoplast dna in trypanosomidae by using a fluorescent compound employed in human cytogenetics. | 1976 | 794608 | |
| [lipid composition of trypanosoma cruzi]. | 1976 | 794622 | |
| [cryopreservation of trypanosoma cruzi in examples of triatoma infestans experimentally infected]. | 1976 | 794979 | |
| [cellular pathology]. | 1976 | 800311 | |
| [alpha-hydroxy-acid dehydrogenase activity in trypanosoma cruzi]. | crude extracts of culture forms of epimastigotes, tulahuén strain, showed activity to catalyze the reaction alpha-ketocid in equilibrium alpha-hydroxyacid linked to nicotinamide adenine dinucleotide (nad). the enzyme utilizes the following substrates: alpha-ketobutyrate, alpha-ketoisovalerate, alpha-keto-beta-methylvalerate, alpha-ketocaproate, alpha-ketoisocaproate, alpha-ketoglutarate and pyruvate. kinetics for the three last substrates were of the michaelian type. for the other ketocids, curv ... | 1976 | 801103 |
| the pyruvate kinase of trypanosoma cruzi. | 1976 | 802627 | |
| the onset of immune protection in acute experimental chagas' disease in c3h(he) mice. | 1975 | 803937 | |
| a vaccination procedure against trypanosoma cruzi infection in mice by nonspecific immunization. | 1975 | 804010 | |
| epidemiological pattern of chagas' disease in an endemic area of costa rica. | triatoma dimidiata was found in association with 34.6% of the houses in a representative town within the dispersion area of the insect. the mean density over the entire study period was 21.5 insects per house, but it tended to be lower in the majority of the houses. insects usually were associated with dirt floors, poor sanitary condition of dwellings, and piles of firewood. the infection rate of 3,276 insects for trypanosoma cruzi was 30.9%. the infection was demonstrated in several synanthropi ... | 1975 | 804266 |
| a direct agglutination test for leishmaniasis. | antigen suspensions of enzyme-treated, formalin-fixed promastigotes of three species of leishmania (l. donovani, l. tropica, and l. braziliensis) were evaluated by using the direct agglutination test with serum samples from healthy individuals and patients with confirmed cases of visceral and cutaneous leishmaniasis. high cross-reactivity was obtained with the three antigens in tests with leishmania sera. sera from patients with kala-azar were 61% to 96% positive when tested with all three antig ... | 1975 | 804268 |
| trypanosoma cruzi: immunoperoxidase antibody test for serologic diagnosis. | 1975 | 804410 | |
| trypanosoma lewisi and t. cruzi: effect of infection on gestation in the rat. | 1975 | 804411 | |
| antiparasitic nitroimidazoles. 8. derivatives of 2-(4-formylstyryl)-5-nitro-1-vinylimidazole. | a series of 33 thioacetals and hydrazones of 2-(4-formylstyryl)-5-nitro-1-vinylimidazole was prepared and examined for antitrypanosomal properties. the thioacetals were inactive as antitrypanosomal agents but three hydrazones derived from n-aminoguanidine, pyridylacethohydrazide chloride (girard reagent p), and dimethylaminoacetohydrazide (girard reagent d) displayed good activity against trypanosoma rhodesiense. | 1975 | 804551 |
| antiparasitic nitroimidazoles. 9. synthesis of some 2-(4-dialkylaminomethylstyryl)-and 2-(4-amidinostyryl)5-nitro-1-vinylimidazoles. | a series of 2-styryl-5-nitro-1-vinylimidazoles carrying alkylaminomethyl or amidino functions in the 4 position of the styryl ring was prepared and evaluated for antitrypanosomal activity in mice infected with trypanosoma rhodesiense. the alkylaminomethyl compounds were found inactive against trypanosoma cruzi infections in mice. one compound, 2-(4-methylamidinostyryl)-5-nitro-1-vinylimidazole hydrochloride, showed antitrypanosomal activity comparable to the standard drugs suramin, pentamidine, ... | 1975 | 804556 |
| [side-effects of ro 7-1051, a nitroimidazole used tentatively as a specific treatment for chagas' disease]. | 2007 | 804715 | |
| trypanosoma cruzi: early immune responses in infected mice. | 1975 | 805059 | |
| the immunology of experimental chagas' disease. ii. delayed hypersensitivity to trypanosoma cruzi antigens. | homogenates of suspensions of the trypomastigote and amastigote forms of the ernestina strain of trypanosoma cruzi, derived from tissue cultures, yielded two subcellular fractions which elicited strong delayed hypersensitivity reactions in rabbits. the 100,000 g times 90 minute fraction of t. cruzi homogenates gave rise to marked cell-mediated immunity. the 30,000 g times 35 minute fraction of these homogenates was also capable of eliciting a marked cell-mediated immune response. cell-mediated i ... | 1975 | 805088 |
| the influence of gonadectomy of host on parasitemia and mortality of mice infected with trypanosoma cruzi. | male cf1 mice were more susceptible to acute infections of trypanosoma cruzi than female mice as evidenced by significantly greater maximum mean parasitemia of approximately 8.9 times 10-6 per ml in males as compared to 1.5 times 10-6 per ml in females. mortality was also greater in males (80 to 90% as compared to 28% in females). ovariectomy of female mice made them more susceptible than unoperated female of similar age and stock to the brazil strain of t. cruzi as indicated by maximum mean par ... | 1975 | 805227 |
| [direct agglutination reaction for the diagnosis of chagas' disease. systematic use of 2-mercaptoethanol for the elimination of nonspecific agglutinins]. | 2015 | 805334 | |
| [acute leukomia and chagas' disease. 4 cases]. | 1975 | 805335 | |
| alterations in normal esophageal motility in patients with chagas' disease. | eight adult patients with visceral chagas' disease were studied twice within an interval of 64 months. in each case the esophagus was evaluated radiologically and manometrically. none of the patients had esophageal symptoms and no significant change in resting gastroesophageal sphincter pressure was observed during the study. however in 3 patients incomplete sphincteric relaxation was noted. normal progressive contractions did not change. the importance of these findings are discussed. | 1975 | 805529 |
| [cardiopathy in americana trypanosomiasis (chagas' disease)]. | 1975 | 805880 | |
| [anatomo-pathological aspects of the skin in congenital chagas' disease]. | 2006 | 806109 | |
| [congenital chagas' disease. study of 29 cases]. | 2006 | 806110 | |
| [acute accidental chagas' disease (through blood transfusion from a chagasic donor)]. | 2006 | 806111 | |
| killing in vitro of trypanosoma cruzi by macrophages from mice immunized with t. cruzi or bcg, and absence of cross-immunity on challege in vivo. | peritoneal macrophages from t. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. resistance in vitro was nonspecific since macrophages from bcg-immune mice were resistant to t. cruzi, and since macrophages from t. cruzi-immune mice were resistant to infection in vitro with listeria were not resistant to challenge with t. cruzi even when the par ... | 1975 | 806649 |
| [editorial: metabolic aspects of chagas' disease]. | 1975 | 806952 | |
| [phonocardiographic systolic parameters and complete atrioventricular block. study in patients of chagas' disease]. | 1975 | 806954 | |
| [systolic quotient of the left ventricle in the chronic form of chagas' disease]. | 1975 | 806955 | |
| letter: in vitro delayed hypersensitivity in chagas's disease (chronic and acute). | 1975 | 806998 | |
| studies on the selective lysis and purification of trypanosoma cruzi. | the mechanism by which culture forms of trypanosoma cruzi are lysed by normal mammalian sera was examined. lysis is restricted to the epimastigote form of the organism and is not dependent on the presence of agglutinins. lysis is a complement-dependent process, the activity being generated by the alternate pathway. the selective lysis by serum was exploited to purify viable trypomastigotes by means of centrifugation in an albumin column. essentially pure trypomastigote populations are now being ... | 1975 | 807672 |
| antigenic differences among epimastigotes, amastigotes and trypomastigotes of trypanosoma cruzi. | antigenic differences were demonstrated among trypomastigotes, amastigotes, and epimastigotes of trypanosoma cruzi by the indirect fluorescent antibody method. tests using cross-absorbed sera were included in the study. | 1975 | 807718 |
| a new liquid medium for trypanosoma (schizotrypanum) cruzi. | a new liquid medium, with fetal calf serum as the sole undefined component, was devised for the cultivation of trypanosoma cruzi. the need for the serum is ascribed to its mitogenic proteins, which stimulate division of, and the uptake of [3-h-] thymidine by the parasites. in the new medium, t. cruzi has a cycle culminating in the apperance of up to 90 per cent metacyclic forms in the stationary phase. this cycle is repeated on each serial transfer. | 1975 | 807720 |
| [urinary catecholamines excretion in experimental rat chagas' disease (levels under basal conditions, after insulin hypoglycemia and under reserpine action (author's transl)]. | 1975 | 807956 | |
| [clinical therapeutic trial in chronic chagas' disease using nifurtimox in 3 schedules of long duration]. | 2007 | 807963 | |
| the evaluation of host efficiency and vector potential of laboratory juvenilized vectors of chagas' disease. i. effects of developmental changes included by juvenile hormone analogues in panstrongylus megistus (hemipterareduviidae) on the ssuceptibility of the insects to gut infection with trypansoma cruzi. | 2003 | 807964 | |
| the immunology of experimental chagas' disease. iv. production of lesions in rabbits similar to those of chronic chagas' disease in man. | eight rabbits that received a single inoculation of trypomastigotes of a virulent strain of trypanosoma cruzi first developed a transient acute illness associated with parasitemia; later, 4 of these rabbits died with chronic myocarditis and/or with megacolon in the absence of demonstrable parasitemia or encysted parasites in tissues. two of these rabbits with chronic myocarditis died unexpectedly. three of the inoculated rabbits that survived the infection were sacrificed 18 months later and s ... | 1975 | 808136 |
| a rapid slide flocculation test for the diagnosis of american trypanosomiasis using trypanosoma cruzi fragments preserved by lyophilization. comparison with hemagglutination, immunofluorescence, and complement fixation tests. | a slide flocculation test for chagas' disease is described, which uses a lyophilized, stable antigen obtained by formalin and ultrasonic treatment of culture forms of trypanosoma cruzi. the test was compared with other tests for the serodiagnosis of american trypanosomiasis and showed a high sensitivity, positive results being obtained in every case of acute or chronic chagas' disease. in sera from blood donors and from normal individuals with negative t. cruzi antigen complement fixation tests ... | 1975 | 808144 |
| chagas' disease in el salvador. | several studies on chagas' disease in el salvador have supplied important epidemiologic information, including the following: (1) rates of house infestation by triatomid vectors have ranged from 26.3 per cent to 100 per cent in various localities studied, higher rates being found in rural than in urban areas. (2) triatoma dimidiata and rhodnius prolixus are the two vectors of t. cruzi in el salvador, with t. dimidiata predominating in localities at elevations above 600 meters and r. prolixus in ... | 1975 | 808244 |
| the effect of bcg on the course of experimental chagas' disease in mice. | 1975 | 808508 | |
| algorithms in the diagnosis and management of exotic diseases. iv. american trypanosomiasis. | 1975 | 808578 | |
| antiprotozoal thiazoles. 2-(5-nitro-2-thienyl)thiazoles. | a series of 2-(5-nitro-2-thienyl)thiazoles and their vinylogs having substituted methylamine side chains has been prepared by halogen displacement on the corresponding 4-chloromethylthiazole. of these, 4-morpholinomethyl-2-(5-nitro-2-thienyl)thiazole showed moderate activity against trypanosoma cruzi and trypanosoma rhodesiense in mice. this compound formed the lead for a series of analogous thiazole-4-carboxaldehyde hydrazones. some of the latter were found active in curing murine tryp. cruzi a ... | 1975 | 808611 |
| survey on experiences with latex-chagas-test in various countries. | the principle of the latex agglutination technique was applied on the serodiagnosis of chagas' disease. the latex particles coated with antigen from trypanosoma cruzi are agglutinated by antibodies against t. cruzi in the serum of patients suffering thereof. in 11600 comparative determinations worked out mainly in a number of south american laboratories, the sensitivity of this test was compared with xenodiagnosis, cf, ift and iha. the latex chagas test shows a mean coincidence of 90% with xenod ... | 1975 | 808885 |
| [study of kinetoplast dna of trypansoma cruzi using restriction endonucleases]. | the cleavage of kinetoplastic dna (kdna) with the restriction endonucleases (eco ri, hind ii + iii, hpa ii) was studied. the quantitative data of electrophoretically separated fragments show that the kdna (free circular genome units and complex network) is composed of distinct populations of circles. kinetic studies of renaturation of kdna previously cleaved by hpa ii into fragments having the length of one genome unit also indicate the presence of at least two and probably three populations of ... | 1975 | 809155 |
| trypanosoma cruzi: new foci of enzootic chagas' disease in california. | 1975 | 809291 | |
| resistance of trypanosoma cruzi to killing by macrophages. | 1975 | 809716 | |
| [antimyocardial antibodies in chronic chagas' disease. correlation between serological results and electrocardiography]. | 1975 | 810118 |