Publications

efficient association of in vitro translation products with purified stable candida tropicalis peroxisomes.	newly synthesized peroxisomal proteins enter preexisting peroxisomes posttranslationally in vivo, generally without proteolytic processing. an efficient reconstitution of this process in vitro together with cloned dnas for peroxisomal proteins would make possible investigation of the molecular information that targets proteins to peroxisomes. we have previously reported the isolation of clones for candida tropicalis peroxisomal proteins; here we describe the association (and possible import) of ...	1987	3600648
kinetics and inhibition studies of catechol o-methyltransferase from the yeast candida tropicalis.	the kms for esculetin and s-adenosyl-l-methionine for catechol o-methyltransferase from the yeast candida tropicalis were 6.2 and 40 microm, respectively. s-adenosyl-l-homocysteine was a very potent competitive inhibitor with respect to s-adenosyl-l-methionine, with a ki of 6.9 microm. of the catechol-related inhibitors, purpurogallin, with a ki of 0.07 microm, showed the greatest inhibitory effect. sulfhydryl group-blocking reagents, such as thiol-oxidizing 2-iodosobenzoic acid and mercaptide-f ...	1987	3611026
import of the carboxy-terminal portion of acyl-coa oxidase into peroxisomes of candida tropicalis.	we report the sequence of a cdna clone that codes for the carboxy-terminal portion of the peroxisomal protein, acyl-coa oxidase, from the yeast, candida tropicalis. this is a newly identified acyl-coa oxidase sequence, most likely a second allele of pox4. the cdna clone was expressed by in vitro transcription followed by translation. the major product, a 43-kd protein, associated with isolated peroxisomes in an in vitro import assay. more than half of the peroxisome-associated protein was protec ...	1987	3611187
candida tropicalis infection in normal, diabetic, and neutropenic mice.	opportunistic infections caused by candida tropicalis have been noted with increasing frequency in compromised patients. the pathogenicity of three isolates of c. tropicalis was studied in normal cd-1 mice, streptozotocin-induced diabetic mice, and cyclophosphamide-induced neutropenic mice. lethal dose 50% endpoints and quantitative distribution of yeast cells in spleen, liver, and kidneys of mice infected intravenously were determined. the virulence of one yeast isolate was greater than that of ...	1987	3624439
possible mycological etiology of oral mucosal cancer: catalytic potential of infecting candida albicans and other yeasts in production of n-nitrosobenzylmethylamine.	yeasts were isolated from 12 cases of oral precancerous lesions (leukoplakia and erythroleukoplakia) by sampling the lesion as well as normal mucosa of each patient, yielding 21 strains of candida albicans belonging to 15 biotypes, two strains of c. tropicalis, one strain of c. parapsilosis and two strains of torulopsis glabrata. biopsies were obtained from the lesions for histologic examination. the catalytic potential of the yeast strains to form n-nitrosobenzylmethylamine (nbma) from the prec ...	1987	3652390
characterization of a soluble carnitine acetyltransferase from candida tropicalis.	carnitine acetyltransferase was purified from the cytoplasmic fraction of candida tropicalis grown on alkanes in continuous culture. by ion-exchange chromatography the enzyme was resolved in two fractions with the same specific activity of 80 u/mg. the molecular mass of both enzyme forms, determined by non-denaturing gradient gel electrophoresis, was 540 kda. after sds electrophoresis only one band of 64 kda was detected indicating that both enzymes are oligomers each containing eight subunits. ...	1987	3665918
synthesis and antimycotic activity of some benzyloxyimino compounds.	some benzyloxyimio compounds, related to oxiconazole and having a 1h-indole or 1h-benzimidazole moiety, have been synthesized and tested in vitro for their antimycotic activity against candida tropicalis and c. albicans. the most active was showed to be 0-(2,4-dichlorobenzyl)-1-benzyl-5-nitro-1h-benzimidazole-2-carboxaldehyd e oxime (mic: 25 micrograms/ml against both microorganisms). a structural feature important for the biological activity of the series appears to be presence of a benzimidazo ...	1987	3671457
nosocomial fungemia in a large community teaching hospital.	this report reviews 48 episodes of hospital-acquired fungemia that occurred over a four-year period at a large community teaching hospital. the incidence of hospital-acquired fungemia increased eightfold during the study period. candida albicans (58%), candida tropicalis (25%), and candida parapsilosis (15%) were the most common fungal pathogens isolated from blood cultures. twenty-one patients (44%) had concomitant bacteremia. intravascular catheters (100%), antibiotic administration (98%), uri ...	1987	3689063
catalase gene of the yeast candida tropicalis. sequence analysis and comparison with peroxisomal and cytosolic catalases from other sources.	a clone harbouring the genomic dna sequence for the peroxisomal catalase of an n-alkane-utilizable yeast, candida tropicalis, has been isolated by the hybrid-selection method and confirmed with a probe of catalase partial cdna. nucleotide sequence analysis of the cloned dna disclosed that the gene fragment coding for catalase had a length of 1455 base pairs (corresponding to 485 amino acids; m = 54937 da), and that the size of this enzyme was the smallest among all catalases reported hitherto. n ...	1987	3691514
peroxisomal acyl-coenzyme a oxidase multigene family of the yeast candida tropicalis; nucleotide sequence of a third gene and its protein product.	we have determined the complete nucleotide sequence of gene pox2, which encodes one of the major peroxisomal polypeptides (pxps) of candida tropicalis. pox2 is linked to gene pox4, which codes for a subunit (pxp-4) of long-chain acyl-coa oxidase. southern blot analysis revealed that pox2 had a significant homology to pox4, and also to gene pox5 which encodes a subunit (pxp-5) of the isozyme of acyl-coa oxidase. pxp-2, the protein product of pox2, was co-purified with pxp-4 from the isolated pero ...	1987	3692174
[process of candida tropicalis adaptation to l-arabinose].	when biotin (an essential growth factor) is removed from the mineral rieder medium, a mutation process is induced, particularly, if a nutrition source (glucose) is present in the medium. hence, a mutation process can be induced under the conditions of an unbalanced 'organism--medium' system.	1986	3702778
candida tropicalis vertebral osteomyelitis and discitis. a case report and discussion on the diagnosis and treatment.		1986	3704784
[effect of pancreatic dnase on the nuclear dna topology of candida tropicalis yeasts].	it has been shown that pancreatic dnaase added to the nutritious medium caused the change in the nuclear dna topology of asporogenic candida tropicalis yeast. dna conformative changes are due to the unwinding of supertwisted molecules as a result of single-strand ruptures formation which induce dna synthesis acceleration, cell growth and division.	1986	3708027
purification of peroxisomal malate synthase from alkane-grown candida tropicalis and some properties of the purified enzyme.	malate synthase, one of the key enzymes in the glyoxylate cycle, was purified from peroxisomes of alkane-grown yeast, candida tropicalis. the enzyme was mainly localized in the matrix of peroxisomes, judging from subcellular fractionation followed by exposure of the organelles to hypotonic conditions. the molecular mass of this peroxisomal malate synthase was determined to be 250,000 daltons by gel filtration on a sepharose 6b column as well as by ultracentrifugation. on sodium dodecylsulfate/po ...	1986	3718151
[biosynthesis of the polyene antibiotic levorin and the membrane composition of streptomyces levoris].	changes in the composition of streptomyces levoris membranes were studied in the course of the polyene antibiotic levorin biosynthesis when the process was stimulated by candida tropicalis metabolites and inhibited by inorganic phosphate. in the presence of stimulating compounds, the percentage of membranes increased in s. levoris cells and the membrane composition changed: the protein-to-lipid ratio and the concentration of total phosphorus decreased while the content of carbohydrates increased ...	1986	3724563
[nature of the stimulating substances found in the vital activity products of yeastlike fungi].	the cultural broth of candida tropicalis was shown to contain an active compound which stimulated the synthesis of levorin, a polyene antibiotic succinic acid was found to stimulate the antibiotic synthesis. the stimulating effect of the active compound increased in proportion to the content of succinic acid in it and became maximal at the same concentration of succinic acid as in a pure preparation. however, succinic acid was not an only compound responsible for the elevated synthesis of the an ...	1986	3724564
antifungal activity of ketoconazole with emphasis on zoophilic fungal pathogens.	the antifungal activity of ketoconazole was studied against fungal pathogens associated with various mycotic infections in animals. a concentration of 10 micrograms of ketoconazole/ml of medium proved fungicidal to trichophyton verrucosum. the same concentration acted as a strong fungistat against the majority of the tested dermatophytes. yeasts were generally more sensitive than yeast-like pathogens. ketoconazole also proved fungicidal against pityrosporon canis and strongly inhibitory on crypt ...	1986	3729122
topical flucytosine therapy for chronic recurrent candida tropicalis infections.	forty-one women with a culture-proven diagnosis of candida tropicalis were treated with miconazole or clotrimazole cream topically or ketoconazole orally. in 15 patients the infection recurred or remained uncured. five-fluorocytosine was compounded into a topical vaginal cream and applied nightly for seven nights. in 14 of the 15 patients the infection disappeared. one patient remains uncured.	1986	3772900
degradation of phenolic compounds by the yeast candida tropicalis hp 15. ii. some properties of the first two enzymes of the degradation pathway.	the first two enzymes of the phenol degradation pathway were determined and characterized in crude extracts from candida tropicalis hp 15. the phenol hydroxylase (ec 1.14.13.7) was a stable nadph2- and fad-dependent enzyme with a ph-optimum of 7.6 to 8.0 and a broad substrate specificity. influence of ultrasound rapidly reduced the enzyme activity. the catechol 1,2-oxygenase (ec 1.13.1.1) had a broad ph-optimum between 7.5 and 9.6 and a limited substrate specificity. two active protein bands ind ...	1986	3783431
the distinction of different types of cytochromes p-450 from the yeasts candida tropicalis and saccharomyces uvarum.	the distinction between two types of cytochromes p-450 originating from microsomes of candida tropicalis grown on glucose and on alkane was achieved. criteria of differentiation between these two cytochrome p-450 forms were based on the characteristics of reduced carbon monoxide difference spectra, on substrate specificity, and on binding and inhibition kinetics of the fungistatic compound propiconazole. one cytochrome p-450 form catalyzed the 14 alpha-demethylation of lanosterol and bound propi ...	1986	3789734
noninvasive and quantitative 19f nuclear magnetic resonance study of flucytosine metabolism in candida strains.	19f nuclear magnetic resonance was used for a noninvasive and quantitative study of flucytosine (fc; 5-fluorocytosine) metabolism in two strains of candida albicans and one strain of candida tropicalis with various susceptibilities to fc. three intracellular fluorinated metabolites were detected in the highly susceptible strain, f-nucleotides (fnt), f-nucleosides, and 5-fluorouracil (5fu). fnt were partially converted into 5fu when the spectra of the yeasts were recorded at 37 degrees c without ...	1986	3800351
candidacidal factors in murine bronchoalveolar lavage fluid.	respiratory secretions provide an efficient method for protecting the large surface area of the lower respiratory tract. to determine whether lung secretions contribute to antifungal defenses, we tested bronchoalveolar lavage fluid for fungicidal activity. candida albicans (blastoconidia) was incubated in unconcentrated cell-free lavage fluid from swiss webster mice and then cultured quantitatively to measure residual viability. in control buffer the residual fractions of viable fungi were 1.03 ...	1987	3818084
5-methyl-2-thiouridine in the trna of candida tropicalis and its localization in lysine trna.	35s incorporation studies showed that candida tropicalis trna contained two thionucleosides, one of which was identified as 5-methyl-2-thiouridine. the other thionucleoside was alkali labile, and it appeared to be an ester. pulse-chase experiments suggested that the two thionucleosides were structurally related. 5-methyl-2-thiouridine was present in one of the lysine trnas. this is the first report of the presence of this nucleoside in a yeast trna.	1985	3845081
candida tropicalis papillary necrosis treated with ketoconazole.		1985	3857483
ocular involvement in patients with fungal infections.	autopsy findings of 133 patients who died following fungemia or with invasive fungal infection were reviewed. common clinical factors included antibiotic therapy, chemotherapy, corticosteroid administration, hyperalimentation, malignancy, and bone marrow transplantation. fungal infection was seldom diagnosed antemortem and fungemia was detected in only 24 patients (18%). ocular involvement occurred in 14 patients (candida 11, aspergillus 2, and cryptococcus 1). the eye was the fifth most commonl ...	1985	3874382
hydrophobic interaction in candida albicans and candida tropicalis adherence to various denture base resin materials.	the effects of hydrophobicities of substrate surfaces on microbial adherence were examined by using candida albicans and candida tropicalis and 21 denture base resin materials. with increasing surface free energy of resin plates, increasing adherence of c. albicans and decreasing adherence of c. tropicalis were observed. the surface free energy of c. albicans is higher than that of all resin material surfaces, and c. tropicalis has surface free energy lower than that of all materials used. in ca ...	1985	3880719
evaluation of the new mycotube test-kit for yeast identification.	the performance of a modified mycotube test for the identification of yeasts was evaluated using standard biochemical tests as reference. one hundred and eighty strains belonging to 12 medically important species (15 strains each) were tested. the overall rate of identification was 72%, and rose to 87.8% when macroscopic and microscopic morphologic features were also considered; a 100% rate was obtained with candida albicans, candida krusei, candida parapsilosis, candida pseudotropicalis, candid ...	1985	3886377
experimental candidiasis in the hamster cheek pouch.	sixty-four adult male bio 87.20 hamsters were divided into four equal groups. animals in three groups had 1 ml of a thick aqueous suspension of either candida albicans (atcc 10261), candida albicans (uo1) or candida tropicalis (3100, puna culture collection) placed in each of their cheek pouches. the fourth group were controls. four animals from each group were killed 1, 2, 4 and 6 weeks following treatment. specimens were removed from all left-cheek pouches and processed routinely for light mic ...	1985	3888159
candida tropicalis vulvovaginitis.	in a majority of patients with candidal vulvovaginitis, drug therapy is convenient and effective. a small but significant group of patients remain symptomatic with recurrent, chronic candidiasis. a study of 805 patients was undertaken to delineate microbiologically candidal species. the study revealed that the recurrence rate for candida tropicalis was twice the rate for candida albicans, and that despite continuous medical care and multiple therapies, the recurrent c tropicalis patients remaine ...	1985	3895072
protection by candida albicans of staphylococcus aureus in the establishment of dual infection in mice.	candida albicans has been shown to stimulate infection in mice by a number of bacteria when both organisms are inoculated intraperitoneally (e. carlson, infect. immun. 39:193-197, 1983). when subcutaneous and intraperitoneal inoculations were given with staphylococcus aureus and c. albicans injected at opposite sites, mixed infection was established at the site of fungal inoculation but not at the site of the bacterial injection. histopathologic evaluation of tissues for the presence of c. albic ...	1985	3905609
characterization of protein and mannan polysaccharide antigens of yeasts, moulds, and actinomycetes.	antigens in coccidioidin were compared with purified subfractions via tandem immunoelectrophoresis (iep) and by a combination of advancing line and crossed iep. rocket iep was suitable for titrating the reactions and showing the relationship between column fractions. these techniques required multicomponent antisera produced by hyperimmunization over many months and by the use of known standard migration pairs. the iep variations were used to chart the development of antisera against coccidioidi ...	1985	3916766
microbial adhesion to fibronectin in vitro correlates with production of endocarditis in rabbits.	microbial adhesion to the constituents of nonbacterial thrombotic endocarditis (nbte) is an important early event in the pathogenesis of infective endocarditis. fibronectin is a ubiquitous mammalian glycoprotein with diverse functions which binds to certain bacteria but not to others. in this study, we determined that fibronectin is present on the surface of nbte (after catheter-induced aortic valve trauma) but not on normal rabbit cardiac valvular endothelium. the adhesion of various bacteria a ...	1985	3936047
[role of lipids in the sensitivity and variability of candida tropicalis d-2 cells to the action of n-methyl-n'-nitro-n-nitrosoguanidine in different solvents].		1986	3950190
pathologic features in the human alimentary tract associated with invasiveness of candida tropicalis.	the pathologic features of candida albicans and candida tropicalis in 23 consecutive autopsied patients with culture-proven disseminated candidiasis were studied in order to determine the pathologic basis for the greater virulence of c. tropicalis. disseminated c. tropicalis infection with gastrointestinal invasion occurred only in eight neutropenic patients; whereas, c. albicans infection occurred in nine neutropenic and six nonneutropenic patients. c. tropicalis involved the entire alimentary ...	1986	3953503
properties of catalase purified from a methanol-grown yeast, kloeckera sp. 2201.	catalase, a marker enzyme of peroxisomes, was purified to homogeneity from whole cells of kloeckera sp. 2201 (a strain of candida boidinii) grown on methanol by means of ammonium sulfate fractionation followed by hydroxyapatite, sephacryl s-300 and deae-sepharose column chromatographies. crystallized catalase was brown-coloured and needle-like. the molecular mass of the enzyme was about 240 000 daltons consisting of four identical subunits of 62 000 daltons. the minimum size of catalase molecule ...	1986	3956497
[characteristics of candida tropicalis d-2 mutants resistant to nystatin, levorin, amphotericin b. i. frequency of induction depending on the intracellular lipid level and phenotypic characteristics of mutants].	induction frequency of mutants of candida tropicalis d-2 strain depends on the number of intracellular lipids and the nature of a chemical mutagen. para-aminobenzoic acid leads to a decrease in the lethality and mutagenicity of nitrosocompounds, which is stronger expressed in cells with enhanced quantity of lipids. among nystatin and levorin-resistant mutants obtained independently, the mutants with supersensitivity to other antibiotics were discovered. the majority of mutants possess cross-resi ...	1986	3957028
stereoisomeric configuration of arabinitol in serum, urine, and tissues in invasive candidiasis.	because routine analytical methods cannot differentiate d- from l-arabinitol, a combined microbiological and gas chromatographic method was developed to study the stereoisomeric configuration of the arabinitol in humans and rats with invasive candidiasis. d-arabinitol was defined as the difference between arabinitol concentrations measured with and without incubation with 5.0 x 10(5) blastospores of candida tropicalis strain ct 12 at 37 c for 24 hr. the yeast consumed at least 95% of the d-arabi ...	1985	3973418
dermatologic manifestations of infections in immunocompromised patients.	thirty-one immunocompromised patients (22 renal allograft recipients, 5 patients receiving chronic corticosteroid therapy, and 4 patients undergoing chemotherapy for acute leukemia) with significant dermatologic infection, excluding typical cellulitis and herpesvirus infections, were retrospectively identified over a 12-year period. of these 31 patients, 15 (48%) had infection restricted to their skin, 6 (19%) appeared to have primary cutaneous infection that spread hematogenously to other parts ...	1985	3974441
peroxisomal beta-oxidation system of candida tropicalis. purification of a multifunctional protein possessing enoyl-coa hydratase, 3-hydroxyacyl-coa dehydrogenase and 3-hydroxyacyl-coa epimerase activities.	a multifunctional protein from oleate-grown cells of candida tropicalis has been purified and partially characterized. a simple two-step purification has been developed involving ion-exchange chromatography followed by dye-ligand chromatography on blue sepharose cl-6b. homogeneous enzyme with a subunit mr of 102 000 is obtained in 60% yield. the native relative molecular mass, determined by three different methods, yielded values which suggest that the enzyme is dimeric. sodium dodecyl sulfate/p ...	1985	3987689
enhancement of carnitine acetyltransferase synthesis in alkane-grown cells and propionate-grown cells of candida tropicalis.	the level of carnitine acetyltransferase was markedly increased in harmony with appearance of peroxisomes in alkane-grown cells and propionate-grown cells of candida tropicalis. from immunochemical studies with antibodies against peroxisomal and mitochondrial carnitine acetyltransferases, it was confirmed that no other type of the enzyme than the peroxisomal and mitochondrial ones was present in alkane-, propionate- and glucose-grown cells of the yeast. the increase in the enzyme level in alkane ...	1985	3994482
production of ethanol from infant food formulas by common yeasts.	four common yeasts (candida albicans, candida tropicalis, torulopsis glabrata and saccharomyces cerevisiae) were combined with five infant food formulas and/or supplements (isomil, nutramigen, 5% glucose, coca cola and similac) and incubated at 37 degrees c. gas chromatography was used to measure ethanol production after 24 and 48 h incubation. the quantities of ethanol produced suggest a possible explanation for patients exhibiting the 'auto-brewery syndrome' and raises interest in the role aut ...	1985	3997687
degradation of phenolic compounds by the yeast candida tropicalis hp 15. i. physiology of growth and substrate utilization.	the yeast candida tropicalis hp 15 was able to utilize phenol up to concentrations of 2.5 g/l as a sole carbon and energy source. phenol was metabolized via the beta-ketoadipate pathway by an inducible enzyme system. besides phenol, resorcinol, quinol, hydroxyquinol, catechol, and to a lesser extend 4-chlorocatechol, protocatechuate, p-cresol, m-chlorophenol, and p-chlorophenol were metabolized by the yeast. a total of 30 aromatic compounds were tested as substrates.	1985	4009428
antifungal properties of 3-n-alkyn-1-ols and synergism with 2-n-alkyn-1-ols and ketoconazole.	twelve 3-n-alkyn-1-ols (c4-c12, c14, c16, and c18) were tested against aspergillus oryzae, aspergillus niger, trichoderma viride, and myrothecium verrucaria in sabouraud dextrose agar at ph 5.6 and 7.0. toxicity to candida albicans, candida tropicalis, trichophyton mentagrophytes, and mucor mucedo was determined in the same medium at ph 5.6 and 7.0 in the absence and presence of 10% beef serum. fungitoxicity was strongly influenced by chain length, slightly by ph of the medium, and significantly ...	1985	4020633
structure-function correlation of fatty acyl-coa dehydrogenase and fatty acyl-coa oxidase.	we have employed a new pseudosubstrate, beta-(2-furyl)propionyl coenzyme a (fpcoa), to study the functional properties of two enzymes, fatty acyl-coa dehydrogenase from porcine liver and fatty acyl-coa oxidase from candida tropicalis, involved in the oxidation of fatty acids. previous studies from our laboratory have shown that the dehydrogenase exhibits oxidase activity at the rate of dissociation of the product charge-transfer complex. this raises the question of the difference in functionalit ...	1985	4040392
use of a new bioassay to study pentamidine pharmacokinetics.	we developed a sensitive and specific agar-diffusion bioassay for pentamidine by using an amphotericin b-resistant isolate, candida tropicalis atcc 28707, as the test organism. we determined levels of pentamidine in serum of rats given intramuscular or intravenous injections and levels in serum, urine, and tissues of humans who had received the drug by slow intravenous infusion. rats given intravenous pentamidine at a dose of 2 mg/kg had higher serum levels than those given intramuscular injecti ...	1985	4045230
invasive candidal balanitis due to a condom catheter in a neutropenic patient.	a 58-year-old man with acute leukemia had balanitis and penile ulceration due to candida tropicalis after a condom catheter was used because of urinary incontinence. this case illustrates that condom catheters can be associated with serious complications in neutropenic patients and should be used only when absolutely necessary.	1985	4049047
fungemia in a cancer hospital: changing frequency, earlier onset, and results of therapy.	two hundred episodes of fungemia that occurred at memorial sloan-kettering cancer center between january 1, 1978, and june 30, 1982, are reviewed and compared with those seen from 1974 through 1977. the total number of episodes of fungemia per year increased by 30.6%, episodes per 100 new lymphoma and solid tumor patients increased by 73% and 95%, respectively, and episodes per 100 new leukemia patients decreased by 50%. fungemia also occurred earlier during hospitalization, and embolic skin les ...	1985	4059756
inhibition by sulfonamides of the candidacidal activity of human neutrophils.	sulfonamides reduced substantially the ability of normal human neutrophils to kill strains of candida albicans and candida tropicalis, and impaired to a lesser extent their activity against staphylococcus aureus 502a and serratia marcescens. sulfonamides also inhibited (a) iodination of candida cells by normal neutrophils; (b) candidacidal activity in cell-free systems containing purified human myeloperoxidase, hydrogen peroxide, and potassium iodide; and (c) accumulation of molecular iodine in ...	1971	4108538
a new aspect of the life cycle of candida tropicalis.		1973	4120625
alkane oxidation in candida tropicalis.		1973	4143948
[study of glutamine synthetase of candida tropicalis fodder yeast].		1973	4144926
[transferase activity of glutamine synthetase from the food yeast candida tropicalis].		1973	4149113
[kinetic properties of the glutamine synthetase of candida tropicalis fodder yeasts in mg2+- and mn2+-activated glutamine synthesis reactions].		1973	4151422
[comparative study of the polyol dehydrogenases of candida tropicalis x9, growing on d-xylose, and of its mutant capable of growing on l-arabinose].		1973	4151661
[kinetic properties of the glutamine synthetase of candida tropicalis yeasts in the transferase reaction].		1974	4152689
[energy metabolism in candida tropicalis. oxidative phosphorylation in candida tropicalis cultivated on alkanes].		1974	4155644
[study of the activity of glutamine synthetase from the food yeast candida tropicalis in the presence of magnesium, manganese and other cations].		1974	4156075
isolation of candida protoplasts from a case of candida endocarditis.	rosner, richard (st. joseph's hospital, paterson, n.j.). isolation of candida protoplasts from a case of candida endocarditis. j. bacteriol. 91:1320-1326. 1966.-a case of endocarditis caused by candida tropicalis is described. even though the patient was receiving adequate therapy, and all routine blood cultures were negative for growth, the patient continued to give clinical evidence of active, progressive endocarditis. the isolation of osmotically fragile bodies from blood cultures placed in a ...	1966	4160231
candida tropicalis and torulopsis glabrata fungemia in a patient treated with long-term hyperalimentation.		1974	4205133
[effect of blue-green algal hydrolysate on candida tropicalis reproduction on a mineral medium with n-alkanes].		1973	4208822
oxidation of phenols by cells and cell-free enzymes from candida tropicalis.		1974	4209029
on the antigenic properties of candida tropicalis.		1969	4247917
prevalence and species distribution of yeast in mammary glands of dairy cows in minnesota.	a study of the prevalence of yeast-like fungi in the mammary glands of dairy cattle was conducted in minnesota. quarter samples from 6,020 cows were cultured for yeast. growth of organisms was obtained from 3.2% of the quarter milk samples. the rate of yeast infection for minnesota dairy cattle in this study was 2.0%. the majority of the yeast isolated belonged to one of four species of the candida genus. candida krusei, candida parakrusei, candida guilliermundi, and candida tropicalis, comprise ...	1972	4263910
trnasglucosyl-amylase of candida tropicalis.	transglucosyl-amylase was purified 96-fold and partially characterized. the k(m) value with dextrin as substrate was 9.1 mg/ml. glycerol, an acceptor of d-glucose, appeared to inhibit dextrin hydrolysis noncompetitively. the energy of activation of the enzyme was 7,920 cal/mole. indirect determinations showed that synthesis of d-glucosyl glycerol was significantly affected by the nature of the amylaceous substrate. glucosyl-glycerol synthesis did not increase as incubation temperature was raised ...	1968	4296315
[some characteristics of soluble polysaccharides from candida tropicalis and candida viswanathii].		1968	4303736
isolation and study of the enzymes involved in the metabolism of hydrocarbons by candida tropicalis.		1970	4319268
general scheme for the metabolisation of hydrocarbons by candida tropicalis.		1969	4319451
polymyxin sensitivity of candida tropicalis.		1970	4319621
[distribution of enzymes and cytochromes in candida tropicalis cultured on alkanes].		1973	4352554
[localization of mitochondrial alcohol dehydrogenase in candida tropicalis].		1974	4370640
[adaptation of the yeast candida tropicalis to l-arabitol].		1969	4391936
[glutamine synthetase regulation in the food yeast candida tropicalis].		1971	4398998
[madura foot due to candida tropicalis].		1972	4402799
[luminescence microscopic detection of selenium in candida tropicalis yeasts].		1974	4407459
[lipid and hydrocarbon composition of candida tropicalis during growth on media with organic acids].		1974	4444555
[several patterns in lipid biosynthesis by thermo-tolerant candida tropicalis yeasts during carbohydrate and hydrocarbon nutrition].		1974	4449487
[the amino acid composition of candida tropicalis protein fractions with different methods of cultivation].		1974	4449490
[oxygen requirement of the thermotolerant, hydrocarbon-oxidizing yeast candida tropicalis].		1974	4453541
[carbohydrate synthesis by thermotolerant candida tropicalis yeasts and micrococcus freudenreichii bacteria].		1974	4465692
[hereditary properties of a strain of candida tropicalis containing virus-like particles].		1974	4470703
the action of n-butyric, n-hexanoic and iso-butyric acids on the respiration of candida tropicalis.		1973	4540256
metabolism of 12-ketooctadecanoic acid by escherichia coli k-12 and candida tropicalis.		1972	4553683
the metabolism of long-chain fatty acids and alcohols by candida tropicalis and saccharomyces cerevisiae.		1973	4570838
phosphatase activity among candida species and other yeasts isolated from clinical material.	a group of 277 yeasts isolated from burned children and 14 reference strains were tested for phosphatase activity by using phenolphthalein phosphate substrates. phosphatase activity was widely distributed among various species and strains representing seven genera. candida albicans, which was the most common yeast isolated from clinical material, was notably absent in producing the enzyme, whereas candida tropicalis was the most consistent, strong, and rapidly active phosphatase-producing organi ...	1973	4584579
resistance to polyene antibiotics and correlated sterol changes in two isolates of candida tropicalis from a patient with an amphotericin b-resistant funguria.		1974	4587944
[virus-like particles in candida tropicalis].		1973	4598916
absence of photoreactivating enzyme in candida albicans. candida stellatoidea, and candida tropicalis.	in vitro assays demonstrate photoreactivating enzyme activity in extracts of candida pseudotropicalis but not in extracts of candida albicans, candida stellatoidea, or candida tropicalis.	1974	4604052
[action of the dna isolated from various sources on the candida tropicalis d-2 his-strain].		1974	4609489
[possible transfer of virus-like particles from candida tropicalis cells to saccharomyces cerevisiae cells].		1974	4615252
[regulation of lipid synthesis under conditions of a varying growth rate in candida tropicalis and in micrococcus freudenreichii].		1974	4616234
octadecanol metabolism in candida tropicalis.		1972	4651253
[effect of dehydration on the available lysine content of candida tropicalis c-36 yeasts].		1972	4655591
[vitamin synthesis by candida tropicalis k-41 yeasts and variants obtained by the action of mutagenic factors].		1972	4663638
[electron microscopic study of the structural characteristics of candida tropicalis k-41 yeasts grown on different sources of carbon].		1972	4670678
[effect of certain growth factors on the content of lysine, methionine and tryptophan in the biomass of candida tropicalis and rhodotorula glutinis].		1972	4677034
[metabolism and distribution of a c-14-polysaccharide preparation from candida tropicalis in mouse organs and tissues].		1972	4679597
assimilation of aliphatic hydrocarbons by candida tropicalis. i. analytical problems in hexadecane batch experiments.		1973	4684076
assimilation of aliphatic hydrocarbons by candida tropicalis. ii. fatty acid profiles from cells grown on substrates of different chain length.		1973	4684077
a peroxidase-mediated, streptococcus mitis-dependent antimicrobial system in saliva.	h(2)o(2) formation by streptococcus mitis was measured by the catalase-dependent conversion of [(14)c]formate to (14)co(2) ; it was optimal at ph 6.0-6.5 and required glucose. the h(2)o(2) formed by s. mitis could be employed as a component of an antimicrobial system that also included lactoperoxidase (lpo) and either iodide or thiocyanate ions in the concentrations present in saliva. the antimicrobial effect of the lpo-iodide-s. mitis system was measured by the decrease in the viable cell count ...	1973	4685704
bovine abortion associated with candida tropicalis.		1973	4692299