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solubilization and accumulation of copper from elementary surfaces by penicillium notatum. 19734803208
changes in composition of conidia of penicillium notatum during germination. 19744836288
transinhibition kinetics of the sulfate transport system of penicillium notatum: analysis based on an iso uni uni velocity equation. 19744847761
lysine inhibition of in vivo homocitrate synthesis in penicillium chrysogenum. 19744853060
penicillin acyltransferase in penicillium chrysogenum.isotopic exchange of (35)s between penicillins and 6-amino-penicillanic acid (6-apa) was observed in cell-free extracts of penicillium chrysogenum. sulfhydryl-containing compounds were required for activity. dithiothreitol, dithioerythritol, mercaptoethanol, and glutathione served as activators. the acyltransferase was purified threefold by adsorption on calcium phosphate gel at ph 6 and elution at ph 8. the partially purified enzyme showed maximal activity at ph 8. the enzyme was stable at 25 c ...19674964480
[on the biosynthesis of penicillin. studies on the enzymatic activation of phenylacetic acid and phenoxyacetic acid as well as the formation of penicillin from 6-aminopenicillanic acid and activated side chain acids by mycelial homogenates and cell-free extracts of penicillium chrysogenum]. 19684969964
specificity of penicillin acylase of fusarium and of penicillium chrysogenum.extracts containing penicillin acylase were obtained by shaking the mycelium of fusarium avenaceum and of penicillium chrysogenum in 0.2 m sodium acetate or sodium chloride solution. the optimum ph for conversion of penicillin v into 6-aminopenicillanic acid (6-apa) by the enzyme of fusarium was about 7.5, and the reaction velocity was increased by a rise in temperature from 27 to 37 c. penicillin g and penicillins with an aliphatic side chain were cleaved much less readily than was penicillin v ...19684971722
comparison of interferon induction in mice by purified penicillium chrysogenum virus and derived double-stranded rna. 19715001254
morphological changes of conidiophores and mycelium of some hyphomycetes. 19715004101
thermal denaturation in acidic solutions of double-helical ribonucleic acid from virus-like particles found in penicillium chrysogenum. a spectrophotometric study.1. two species of double-helical rna isolated from mycelium of penicillium chrysogenum were titrated with acid at 25 degrees c and 95 degrees c (solvent 0.1m-sodium phosphate buffer). at 25 degrees c denaturation occurred at about ph3. at 95 degrees c in the denatured form cytosine residues titrated as a simple monobasic acid of pk3.9 compared with pk approximately 2.5 for the native form at 25 degrees c. 2. on thermal denaturation in neutral and acidic solutions one species of rna (38% rg.rc) ; ...19715004201
[on the incidence and analytic procedure of cyano-5,6-dimethylbenzimidazolylcobamide in the mycelia of penicillium chrysogenum]. 19715004691
atp-sulfurylase from penicillium chrysogenum. i. purification and characterization. 19715005722
purification and properties of 6-phosphogluconate dehydrogenase from penicillium duponti and penicillium notatum. 19725052896
[metabolites of the xanthocillin(brevicid)-producing mutant of penicillium notatum westl]. 19725084576
effect of peat extract on the antibiotic activity of penicillium chrysogenum. 19715113364
acidic and basic amino acid transport systems of penicillium chrysogenum. 19715117525
biochemical properties of haploid and diploid strains of penicillium chrysogenum.an intensive parasexual genetics program in which industrial strains of penicillium chrysogenum were used culminated in the isolation of a number of heterozygous diploid strains. the diploid clones were selected from heterokaryons formed from matings between mutant strains having complementary biochemical and conidial color markers. several diploid cultures were compared with their haploid wild-type parents and other distantly related production strains on the basis of a variety of cultural and ...19715119205
fine structure of resting and germinating penicillium chrysogenum conidiospores. 19715125905
segregants from a heterozygous diploid of penicillium chrysogenum following different physical and chemical treatments. 19715132280
[sulfur containing substances of penicillium chrysogenum fermentation broth during penicillin biosynthesis]. 19715140748
virus-like particles in penicillin producing strains of penicillium chrysogenum. 19695191625
differences in diploids synthesized between the same parental strains of penicillium chrysogenum. 19665297393
production of calcium gluconate by penicillium chrysogenum in submerged culture.the waste mycelium of penicillium chrysogenum ha-10 (obtained at the end of penicillin fermentation), or a 24-hr-old freshly grown vegetative inoculum of this organism, was found to utilize glucose for the production of calcium gluconate by submerged fermentation in shake flasks. after 72 to 96 hr of fermentation at 24 c, 90 to 95% of the reducing sugar from the 15% glucose medium was converted to calcium gluconate. reuse of the mycelium for successive experiments reduced the fermentation period ...19655325935
the chemistry and molecular architecture of the cell walls of penicillium chrysogenum. 19695348600
[mechanism of action of glucose oxidases from aspergillus niger and penicillium notatum]. 19695362013
[refining of production strains of penicillium chrysogenum]. 19695364002
end-product control of acetohydroxyacid synthetase by valine in penicillium chrysogenum q 176 and a high penicillin-yielding mutant. 19695365361
components of conidial and hyphal walls of penicillium chrysogenum. 19695365925
[respiration of penicillium chrysogenum 194 during fermentation of penicillin]. 19695401107
[somatic segregation of penicillium chrysogenum strain 194]. 19695404301
effect of heavy water on three high producing strains of penicillium chrysogenum. 19705416195
independent regulation of cysteine and cystine transport in penicillium chrysogenum. 19705446343
contribution to the morphology of the productive strains of penicillium chrysogenum thom from the wisonsin family. 19705480313
multiple activities of penicillin acyltransferase of penicillium chrysogenum. 19705484680
changes in constituents and ultrastructure of hyphal compartments during autolysis of glucose-starved penicillium chrysogenum. 19705488056
[penicillium chrysogenum exonuclease]. 19705490452
conformation of nucleic acids and the analysis of the hypochromic effect.the spectra of two double-helical rna species isolated from virus-like particles found in the mycelium of penicillium chrysogenum were measured at about 25 degrees c, and at 95 degrees c after denaturation to a single-stranded form, and compared with the spectrum of the equivalent mixture of nucleotides. for both species the difference spectrum (epsilon(95 degrees c)-epsilon(25 degrees c)) when increased by 33% was very similar to the difference spectrum (epsilon(nucleotides)-epsilon(25 degrees ...19705499966
double-helical character of ribonucleic acid from virus-like particles found in penicillium chrysogenum.1. rna was isolated from virus-like particles found in penicillium chrysogenum and resolved into two fractions by gel filtration through agarose columns. 2. fraction 1 was excluded and had the following properties: 50.9% g+c [amp 0.246, ump 0.246, cmp 0.252, gmp 0.255 (mole fraction)]; mol.wt. about 1.2x10(6) daltons; s(20,w) 12.3s and ;melting' temperature about 100 degrees c (solvent 0.15m-sodium chloride-0.015m-sodium citrate ph7.2); optical rotation [alpha](max.) 6000 degrees at 278nm; circu ...19705499967
penicillin titer after storage of penicillium chrysogenum by liquid nitrogen refrigeration. 19705510617
adenosine triphosphate sulfurylase from penicillium chrysogenum. ii. physical, kinetic, and regulatory properties. 19715553402
haploidization analysis in penicillium chrysogenum. 19715559615
[phenoxazinones in culture media solutions of penicillium notatum westl]. 19715563065
evidence of an intracellular proteinase of penicillium chrysogenum. 19715579219
self stimulation and self inhibition in penicillium chrysogenum. 19675591332
[on the primary stages of orthophosphate absorbion by mycelium of penicillium chrysogenum]. 19675592286
[storage and mutation of the penicillin producent--penicillium chrysogenum strain 194 a]. 19675593953
effect of co-2 on the germination of penicillium chrysogenum spores. 19675598142
a non-discriminating proteinase of penicillium notatum. partial purification and specificity. 19685636374
microbiology of saturated salt solutions and other harsh environments. iv. new observations on ribonucleotide-induced recovery of kcl-habituated penicillium notatum.salt-tolerant mutant penicillium notatum sub-cultured in a glucose-peptone broth saturated with kcl shows continued attenuated growth when transferred to salt-free broth. additional tests have shown e. coli s-rna to be inferior to yeast rna preparations, that base-free phosphate sources are inactive, but that nicotinamide adenine dinucleotide and flavine adenine dinucleotide are moderately active. all phosphate derivatives of adenine, cytosine and guanosine and inosine were active including 5'-p ...19685638041
studies on cellulolytic enzymes. 3. isolation of a cellulase from penicillium notatum. 19685642601
studies on the lecithinase from penicillium notatum. 19685646049
the influence of maintenance energy and growth rate on the metabolic activity, morphology and conidiation of penicillium chrysogenum. 19685652074
studies on cellulolytic enzymes. iv. chemical and physiochemical characterization of a cellulase for penicillium notatum. 19685661595
studies on cellulolytic enzymes. v. some structural properties of the cellulase from penicillium notatum. 19685661596
influence of hydrogen ions on the stability and structure of a cellulase from penicillium notatum. 19685661619
the persistence of parental genome segregation in penicillium chrysogenum after nitrogen mustard treatment. 19685672976
[to the study on natural variability of penicillium chrysogenum strain 194]. 19685674783
structure and function of a cellulase from penicillium notatum as studies by chemical modification and solvent accessibility. 19685686590
lysine control of alpha-aminoadipate and penicillin synthesis in penicillium chrysogenum. 19685704806
studies on the synthesis of valine moiety of 6-aminopenicillanic acid by preformed mats of penicillium chrysogenum. 19685706415
isolation of a water-soluble polysaccharide from the mycelium of penicillium chrysogenum. (studies on fungal polysaccharides. v.). 19685709239
fatty acid composition of mycelium of penicillium chrysogenum grown in different carbohydrates as a sole source of carbon. 19685721123
specificity and control of choline-o-sulfate transport in filamentous fungi.choline-o-sulfate uptake by penicillium notatum showed the following characteristics. (i) transport was mediated by a permease which is highly specific for choline-o-sulfate. no significant inhibition of transport was caused by choline, choline-o-phosphate, acetylcholine, ethanolamine-o-phosphate, ethanolamine-o-sulfate, methanesulfonyl choline, 2-aminoethane thiosulfate, or the monomethyl or dimethyl analogues of choline-o-sulfate. similarly, no significant inhibition was caused by any common s ...19685726299
purification of an extracellular proteinase from penicillium notatum. 19685726849
biosynthesis of penicillins. i. isolation of a 6-aminopenicillanic acid acyltransferase from penicillium chrysogenum. 19685727632
[on the presence of polymeric form phosphate in mycellium of penicillium chrysogenum q-176]. 19685727714
multiplicity and regulation of amino acid transport in penicillium chrysogenum. 19695772963
studies on cellulolytic enzymes. vi. specificity and mode of action on different substrates of a cellulase from penicillium notatum. 19695778644
synthesis of unsaturated fatty acids by penicillium chrysogenum. 19695778670
chemical structure of an intracellular polysaccharide of penicillium chrysogenum (studies on fungal polysaccharides. vi). 19695782966
degradation of xanthine by penicillium chrysogenum. 19695793119
studies on nitrogen metabolism of penicillium chrysogenum thom. i. effects of lactose and sucrose additions on nitrogen metabolism. 19655824967
studies on nitrogen metabolism of penicillium chrysogenum thom. ii. amino acid metabolism and its relation to the biosynthesis of penicillin. 19655824968
penicillin acylase activity of penicillium chrysogenum.the penicillin acylase activity of penicillium chrysogenum was studied. washed mycelial suspensions of a high penicillin-producing and a nonproducing strain were found to be similar in respect to relative acylase activity on benzylpenicillin, 2-pentenylpenicillin, heptylpenicillin, and phenoxymethylpenicillin. the relative rates for both strains, as determined by 6-aminopenicillanic acid formation, were approximately 1.0, 2.5, 3.5, and 6.0 on the penicillins in the order given. the high producin ...19655867654
invertase production by penicillium chrysogenum and other fungi in submerged fermentation.a study was made of penicillium chrysogenum and some other fungi to determine the relative distribution of intra- and extracellular invertase produced by them in submerged fermentation. the proportion of each type of enzyme varied with the organism and the period of fermentation. more of the enzyme initially bound to the mycelium was released into the medium with the progress of fermentation. differences were observed in the effects of cultural conditions on enzyme production in p. chrysogenum a ...19655867655
[the influence of lactose concentrate on the activity of penicillin formation from penicillium chrysogenum]. 19655868968
[isolation and purification of ribonuclease from the mycelium of penicillium chrysogenum stain 194]. 19655869036
[general characteristics of some new nucleotide-containing acid soluble compounds isolated from mycelia of penicillium chrysogenum thom]. 19655871318
[investigation of ribonuclease and desoxyribonuclease activity of the mycelium of penicillium chrysogenum, strain 194]. 19655871935
heterozygous diploids of penicillium chrysogenum and their segregation patterns. 19655881991
biosynthesis of benzylpenicillin. ii. effect of precursor amino acids on the biosynthesis of benzylpenicillin by the washed, resting cells of penicillium chrysogenum. 19665942689
negapillin, a new antibiotic isolated from metabolites of penicillium chrysogenum. 19665952016
the inorganic sulfate transport system of penicillium chrysogenum. 19665957709
an unusual amino sugar derivative from the cell wall of penicillium notatum. 19665970173
[isolation of alpha-amylase from the mycelium penicillium chrysogenum strain 194]. 19665986874
incorporation of amino acids into protein by cell-free extracts of penicillium chrysogenum. 19665988123
[organic phosphorus compounds of penicillium chrysogenum containing phosphorus determined as orthophosphate]. 19665994934
nonenzymatic and enzymatic hydroxylation of phenylacetic acid in penicillium chrysogenum cultures. 19665998188
[sedimentation and diffusion coefficients from the transport of enzymatic activities. application of the method of determination to the glucose oxidases from penicillium notatum (notatin) and aspergillus niger (nigerin)]. 19676030353
use of dried mycelium of penicillium chrysogenum as the only constituent of seed medium in penicillin fermentation. 19676035149
microbiology of saturated salt solutions and other harsh environments. ii. ribonucleotide dependency in the growth of a salt-habituated penicillium notatum in salt-free nutrient media.a strain of penicillium notatum has been found growing upon media containing saturated calcium acetate which upon passage through media containing saturated kc1 loses its ability to grow at normal rates in salt-free glucose-peptone medium. this salt-habituated form can be restored to a near-normal growth rate by adding yeast extract, rna or rna-hydrolysates, but not by dna or its hydrolysate. the 4 rna nucleotides in combination replace yeast extract whereas riboside and base combinations do not ...19676040891
on the mechanism of the stimulation by anionic amphipaths of lecithin hydrolysis by phospholipase b of penicillium notatum. 19676049946
experimental microbiology of saturated salt solutions and other harsh environments. 3. growth of salt-tolerant penicillium notatum in boron-rich media.a stress-tolerant strain of penicillium notatum, isolated by passage through a nutrient solution saturated with calcium acetate, was found to have a tolerance to boron in several states of oxidation. growth in the presence of elementary boron, saturating amounts of boric acid, and with various concentrations of sodium borohydride was observed and mycelial mats were spectrographically analyzed for boron accumulation.19676076112
[a statistical method for the determination of the yield correlation of antibiotic-producing microorganisms].the antibiotic yields of industrial selectants must be checked at several steps of cultivation. here the question arises whether the activities at the different levels of cultivation are correlated. the common coefficient of correlation cannot be used because repeated determinations of the yield at one selectant result in different values. in order to have only one fixed value per selectant we define the mean value around which the observed values are varying. but these mean values cannot be obs ...19846089455
biosynthesis of penicillins and cephalosporins in cell-free systems. 19806109332
[localization of various stages of penicillin g biosynthesis in the subcellular structures of penicillium chrysogenum pq-96]. 19816115997
the microbiological production of pharmaceuticals. 19816116278
induction of penicillin biosynthesis by l-glutamate in penicillium chrysogenum. 19826124245
[induction of the biosynthesis of penicillin by l-glutamate in penicillium chrysogenum]. 19836152679
interferon induction and macrophage activation by a mycovirus double-stranded rna/tobramycin complex following treatment with human serum.double-stranded rna (dsrna) molecules, generally effective inducers of interferon (ifn), have a weak potency in man apparently because of the presence of a serum rnaase which quickly inactivates extracellular dsrna. we have discovered that tobramycin, an aminoglycoside, protects penicillium chrysogenum mycovirus dsrna (pcmdsrna) from the degradative action of the nuclease. exposure of the dsrna/tobramycin complex to human serum results in some degradation, but still permits the production of sig ...19826183374
Displaying items 401 - 500 of 1965