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chinese bellflower root anaphylaxis: ige-binding components and cross-reactivity with mugwort and birch.a 56-year-old man who had suffered from seasonal rhinitis in spring and autumn experienced recurrent generalized urticaria and an oral burning sensation after eating several cooked herbs for 3 months. a skin-prick test showed positive responses to various pollens, celery, chinese bellflower, and arrowroot. the chinese bellflower-specific ige elisa od value was 1.547. oral challenge with unprocessed raw chinese bellflower root provoked oral burning sensation, eyelid swelling, generalized urticari ...200919721867
antispasmodic and bronchodilator activities of artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx.the present study describes antispasmodic, antidiarrheal, bronchodilatory and tracheo-relaxant activities of artemisia vulgaris to rationalize some of its traditional uses.200919751814
assessment of component-resolved in vitro diagnosis of celeriac allergy.previous studies have demonstrated insufficient sensitivity of commercially available celeriac extract reagents in the diagnosis of celeriac allergy.200919800675
factors affecting the success of moxibustion in the management of a breech presentation as a preliminary treatment to external cephalic version.to explore the effects of moxibustion treatment, to examine the predictors of its use in causing a breech presentation to spontaneously turn to a cephalic presentation which will result in a vaginal birth (the paper will refer to this as 'successful') and offer external cephalic version (ecv) subsequently after moxibustion treatment when the fetus remains in a breech presentation.200919853333
food-dependent exercise-induced anaphylaxis in the celery-mugwort-birch-spice syndrome. 201019860787
anaphylaxis to mango fruit and crossreactivity with artemisia vulgaris pollen. 200919862948
in vitro cross-reactivity between tomato and other plant allergens.cross-reactivity among fruits and different pollen and fruit species has been extensively reported.200919927542
anthelmintic effects of phytogenic feed additives in ascaris suum inoculated pigs.two experiments were performed to determine the anthelmintic effect of some phytogenic feed additives on a mild infection of ascaris suum in growing and finishing pigs. usually, an infection of a. suum is controlled by using conventional synthetic drugs. organic farmers, however, prefer a non-pharmaceutical approach to worm control. therefore, phytotherapy could be an appropriate alternative. in the first experiment, a commercial available organic starter diet was supplemented with 3% of a herb ...201019954891
did the introduction of maize into europe provide enemy-free space to ostrinia nubilalis? parasitism differences between two sibling species of the genus ostrinia.we examined whether maize offers enemy-free space (efs) to its pest ostrinia nubilalis, and may thereby have contributed to its divergence from the sibling species, ostrinia scapulalis, feeding mainly on mugwort, when introduced into europe five centuries ago. we collected ostrinia larvae on maize (70 populations, 8425 individuals) and mugwort (10 populations, 1184 individuals) and recorded parasitism using both traditional (counting emerging parasitoids) and molecular methods (detection by spec ...201020002249
production and characterisation of the intergeneric hybrids between dendranthema morifolium and artemisia vulgaris exhibiting enhanced resistance to chrysanthemum aphid (macrosiphoniella sanbourni).aphids represent the most destructive of chrysanthemum pests to cultivation. reliable variety sources of resistance and control methods are limited, so development of highly resistant breeding lines is desirable. an intergeneric hybrid between dendranthema morifolium (chrysanthemum) variety 'zhongshanjingui' and artemisia vulgaris (mugwort) 'variegata' was attempted. most of the hybrid embryos aborted at an early developmental stage. embryo rescue allowed the generation of hybrid plants, whose h ...201020012083
targeting the cysteine-stabilized fold of art v 1 for immunotherapy of artemisia pollen allergy.plants of the genus artemisia domestic in northern and central europe, usa and parts of asia are a major cause of allergic symptoms from late summer to autumn. art v 1, the major mugwort pollen allergen appears as two-domain glycoprotein, consisting of an n-terminal defensin-like and a proline/hydroxyproline-rich c-terminal part. patients sensitized to art v 1 commonly display ige antibodies against the cysteine-stabilized defensin fold. site-directed mutagenesis of eight cysteines was used to d ...201020022115
thymic stromal lymphopoietin expression is increased in nasal epithelial cells of patients with mugwort pollen sensitive-seasonal allergic rhinitis.excessive expression of thymic stromal lymphopoietin (tslp) has been demonstrated in asthmatic airway epithelia and in nasal epithelia from animal models of allergic rhinitis (ar), but the evidence of expression of tslp in nasal epithelial cells (necs) of patients with ar is lacking. we aimed to investigate the expression of tslp in necs of patients with mugwort sensitive-seasonal ar and determine whether it is associated with severity of symptoms and the number of infiltrated eosinophils in nas ...200920079130
[concentration of airborne pollen in beijing city with burkard sampler].to investigate the airborne pollen concentration in beijing city during autumn and to grade the artemisia pollen concentration.200920128277
effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.allergic rhinitis, a disease that impairs quality of life, is characterized by inflammation due to an allergic reaction. fexofenadine is a second-generation histamine receptor blocker well known for its potent interaction with this inflammatory process. the main aim of this study was to further clarify the anti-inflammatory effects exerted by fexofenadine in patients with intermittent allergic rhinitis.200920128420
allergic contact dermatitis associated with mugwort (artemisia vulgaris). 201020136887
antibacterial activity of some artemisia species extract.the antimicrobial activities of ethanol, methanol and hexane extracts from artemisia absinthium, artemisia annua and artemisia vulgaris were studied. plant extracts were tested against five gram-positive bacteria, two gram-negative bacteria and one fungal strain. the results indicated that artemisia annua alcoholic extracts are more effective against tested microorganisms. however, all plants extracts have moderate or no activity against gram-negative bacteria. the obtained results confirm the j ...201120191854
preliminary results of a skin prick test-based study of the prevalence and clinical impact of hypersensitivity to pollen panallergens (polcalcin and profilin).calcium-binding proteins (polcalcins) and profilin are cross-reacting panallergens that sensitize a minority of pollen-allergic patients. their clinical relevance remains controversial.201020232772
accuracy of a point-of-care testing device in children with suspected respiratory allergy.measuring ige antibodies is useful in the diagnostic workup of allergy and asthma. this study was designed to assess the value of a new point-of-care test (immunocap rapid wheeze-rhinitis child [icr]; phadia ab, uppsala, sweden) in the diagnosis of atopy in children with allergy-like symptoms such as rhinitis, eczema, and recurrent episodes of wheezing. patients (n = 175; average age, 7.2 years) referred from primary care were consecutively enrolled in two pediatric allergy referral centers in i ...201020236576
[investigation on the real herb of mugwort leaf and the standard of its processing for moxibustion].mugwort leaf is the traditional herb being used for moxibustion. although its place of production and the course of making mugwort floss have been described in detail, there is no unified standard about the quality and processing of mugwort floss until now, which seriously affect on the popularity and application of moxibustion. in accordance with the real herb of mugwort leaf and floss as well as its processing and quality judgment, this paper thoroughly analyze the related data including ancie ...201020353113
[epidemiological investigation of allergic rhinitis in the primary school students in grade three of shihezi city].to investigate the epidemic features of allergic rhinitis(ar)and correlative risk factors in shihezi city, xinjiang province, china.200920359108
moxibustion for cancer care: a systematic review and meta-analysis.moxibustion is a traditional chinese method that uses the heat generated by burning herbal preparations containing artemisia vulgaris to stimulate acupuncture points. considering moxibustion is closely related to acupuncture, it seems pertinent to evaluate the effectiveness of moxibustion as a treatment of symptoms of cancer. the objective of this review was to systematically assess the effectiveness of moxibustion for supportive cancer care.201020374659
correlation of oral allergy syndrome due to plant-derived foods with pollen sensitization in japan.the clinical features of patients with oral allergy syndrome (oas) due to plant-derived foods related to pollen allergy have been rarely reported in japan.201020377109
nasal nitric oxide and other diagnostic procedures in seasonal allergic rhinitis: elderly vs juvenile patients.the type of allergy and other diagnostic procedures were analyzed in a group of elderly seasonal allergic rhinitis (sar) patients and were compared with young sar people and a control group.201520378200
identification of bet v 1-related allergens in fig and other moraceae fruits.allergy to fig fruit (ficus carica) has been described in patients allergic to ficus benjamina or rubber latex but may occur also in pollen-allergic patients.201020447079
bee pollen: a dangerous food for allergic children. identification of responsible allergens.bee pollen has been proposed as a food supplement, but it can be a dangerous food for people with allergy. we study an allergic reaction after ingestion of bee pollen in a 4-year-old boy who had developed rhinitis in the last spring and autumn.201020447747
[investigation and analysis of the common inhaled allergens in allergic diseases in jingmen area of hubei province].in order provide important evidences for epidemiologic survey, clinical diagnosis, treatment and preservation of allergic diseases in this area, we investigate the distribution of the common allergens in allergic rhinitis and allergic asthma in jingmen area and the sensitization condition of the major allergen house dust mite.201020464983
[analyzing of the inhaled allergens profiles of allergic rhinitis patients in district of jingmen].to investigate the profiles of inhaled allergens in allergic rhinitis patients in district of jingmen, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis in this area.201020556967
a new allergen from ragweed (ambrosia artemisiifolia) with homology to art v 1 from mugwort.art v 1, the major pollen allergen of the composite plant mugwort (artemisia vulgaris) has been identified recently as a thionin-like protein with a bulky arabinogalactan-protein moiety. a close relative of mugwort, ragweed (ambrosia artemisiifolia) is an important allergen source in north america, and, since 1990, ragweed has become a growing health concern in europe as well. weed pollen-sensitized patients demonstrated ige reactivity to a ragweed pollen protein of apparently 29-31 kda. this re ...201020576600
moxibustion for hypertension: a systematic review.moxibustion is a traditional east asian medical therapy that uses the heat generated by burning herbal preparations containing artemisia vulgaris to stimulate acupuncture points. the aim of this review was to evaluate previously published clinical evidence for the use of moxibustion as a treatment for hypertension.201020602794
mapping the interactions between a major pollen allergen and human ige antibodies.the interaction of specific ige antibodies with allergens is a key event in the induction of allergic symptoms, thus representing an important target for therapeutic interventions in type i allergies. we report here the solution nmr structure of art v 1, the major mugwort pollen allergen. art v 1 is the first protein structure with an allergenic defensin fold linked to a polyproline domain, which has not been identified in any reported allergen structure in the pdb. moreover, the direct interact ...201020696401
mugwort-sensitized individuals from north europe, south europe and north america show different ige reactivity patterns.sensitization to weed pollen allergens at the molecular level is not fully understood. we studied ige reactivity to the major mugwort allergen art v 1 in relation to allergens from other weed pollen and cross-reactive components in mugwort-sensitized subjects.201120733325
platanus pollen allergen, pla a 1: quantification in the atmosphere and influence on a sensitizing population.the allergic response in susceptible patients does not always coincide with the presence and magnitude of airborne pollen counts. the prevalence of allergy to platanus is currently moderate, although the percentage of monosensitized patients is low. this hinders accurate interpretation of the relationship between the amount of pollen inhaled and the patient's symptoms.201020813013
[relationship between ige antibodies to recombinant allergens rbet v 1 and rbet v 2 and food causing oral allergy syndrome in cases of birch-pollen allergy].persons allergic to birch pollen often report oral and pharyngeal hypersensitivity to fruit and vegetables, such as apples and peaches due to immunological cross-reactivity, or oral allergy syndrome (oas) sometimes accompanied by systemic reaction. such cross-reactive antigen reactions involve bet v 1, the main birch-pollen allergen, and bet v 2, birch-pollen profilin. we evaluated the food/antigen relationship.201020845708
bioengineering assessment of acupuncture, part 8: innovative moxibustion.the actual chinese character for acupuncture, translated literally, means "acupuncture-moxibustion." this shows the enormous importance of moxibustion in asia for thousands of years. in this review article, the history of the burning of mugwort (moxatherapy) is briefly described. in addition, new technical methods such as new infrared-moxa or laser-moxa devices, electrobian stone moxibustion, and the investigations of a new needle-moxa system using high-tech methods such as thermography, laser d ...201020932234
synthesis of a dimer of β-(1,4)-l-arabinosyl-(2s,4r)-4-hydroxyproline inspired by art v 1, the major allergen of mugwort.nα-tert-butoxycarbonyl-l-trans-4-hydroxyproline allyl ester (boc-hyp-oall) was glycosylated with 2,3,5-tri-o-benzyl-l-arabinose p-cresylthioglycoside in 60% yield with 4:1 β:α stereoselectivity. deprotection of n- and c-terminii independently gave a prolyl amine and prolyl carboxylate respectively that were coupled under standard conditions with 1-[bis-(dimethylamino)methylene]-1h-1,2,3-triazolo-[4,5,b]-pyridininium hexafluorophosphate 3-oxide (n-hatu) to give the dimer 1 in 46% yield. these res ...201020936855
evaluation of serum specific ige for the diagnosis of allergic rhinitis with multi-allergens.objective evaluation of allergic rhinitis (ar) requires in vivo and in vitro tests. in vitro tests are important to assist or ensure the main allergens in multi-allergen-sensitive patients. the aim of this study was to evaluate the utility of serum specific ige (sige) in the diagnosis of ar patients with multi-allergens in the chinese population.201021034593
the specific ige reactivity pattern of weed pollen-induced allergic rhinitis patients.specific immunoglobulin e (ige) reactivity towards the major mugwort allergen art v 1 is a good indicator for art v sensitization. allergens from the ragweed species amb t and amb a possibly share common ige-binding epitopes.201121189055
[clinical characteristics in patients with non-allergic rhinitis and allergic rhinitis: preliminary analysis].to compare and analyze the clinical characteristics in patients with hyperreactive non-allergic rhinitis (hnar) and allergic rhinitis (ar).201021215048
allergic rhinitis (ar) in geriatric patients.allergic rhinitis (ar) can be defined as an inflammatory disease of the nose and the paranasal sinuses, characterized by a specific ige-mediated hypersensitivity reaction. the aim of this study was to evaluate the correlation between the symptoms of ar and the prick test results in geriatric patients presenting with symptoms of ar by comparing these with those of a young control group. thirty-two geriatric patients (group 1) were analyzed retrospectively, and 37 patients (group 2) were selected ...201121227518
production of recombinant allergens in plants.a large percentage of allergenic proteins are of plant origin. hence, plant-based expression systems are considered ideal for the recombinant production of certain allergens. first attempts to establish production of plant-derived allergens in plants focused on transient expression in nicotiana benthamiana infected with recombinant viral vectors. accordingly, allergens from birch and mugwort pollen, as well as from apple have been expressed in plants. production of house dust mite allergens has ...200821258627
co-recognition of lipid trasfer protein in pollen and foods in northern italy: clinician's view.lipid transfer proteins (ltp) are pan-allergens in plant derived foods that have been also detected in several pollens. the observed cross-reactivity between pollen and plant-food ltps has led to hypothesize that primary sensitisation to this allergen may occur through the airways.201021287943
correlation analysis of two serum-specific immunoglobulin e test systems and skin-prick test in allergic rhinitis patients from northeast china.skin-prick testing (spt) is the most common screening method for allergy evaluation. the detection of serum-specific immunoglobulin e (sige) is also commonly used. the sensitivity and specificity of these testing methods may vary due to type of causative allergen and type of allergic manifestation. the purpose of this study was to evaluate the correlation between two methods of measuring sige (allergyscreen [mediwiss analytic gmbh, moers, germany] and immunocap [pharmacia, uppsala, sweden]) and ...201121294972
scanning the european corn borer (ostrinia spp.) genome for adaptive divergence between host-affiliated sibling species.it has recently been shown that the european corn borer, a major pest of maize crops, is actually composed of two genetically differentiated and reproductively isolated taxa, which are found in sympatry over a wide geographical range in eurasia. each taxon is adapted to specific host plants: ostrinia nubilalis feeds mainly on maize, while o. scapulalis feeds mainly on hop or mugwort. here, we present a genome scan approach as a first step towards an integrated molecular analysis of the adaptive ...201121375617
molecular characterization of api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.celery represents a relevant cross-reactive food allergen source in the adult population. as the currently known allergens are not typical elicitors of severe symptoms, we aimed to identify and characterize a non-specific lipid transfer protein (nsltp).201121462324
analysis of the allergenic profile of patients hypersensitive to pollen pan-allergens living in two distinct areas of northern italy.the allergenic profile of patients hypersensitive to pollen pan-allergens, profilin and polcalcin, has received little attention so far.201121608373
safety of ultrashort-term sit with pollen allergoids adjuvanted by monophosphoryl lipid a: a prospective italian survey.a 3-year prospective post marketing survey on the safety of the recently developed ultrashort pre-seasonal subcutaneous immunotherapy (uscit-mpl4) with pollen allergoids adjuvanted with monophosphoryl lipid a was performed. a total of 510 patients received uscit-mpl4, 61% for grass, 35.7% for birch, 13.2% for parietaria and 3% for other pollens (ragweed, mugwort, and olive). a total of 3308 injections were given and the mean duration of uscit-mpl-4 was 2.3 years. overall, only 7 slight systemic ...201121608374
[two cases of royal jelly allergy provoked the symptoms at the time of their first intake].two young women were suffered from several symptoms after the intake of royal jelly at their first time. according to the positive skin prick test reactions of raw royal jelly, royal jelly allergy was diagnosed. as the reasons why the symptoms appeared at the time of their first intake, we guessed the possibility that 1) they had been sensitized for royal jelly formerly, or 2) their symptoms were induced by the cross-reactivity between royal jelly and other allergens such as bee, honey and polle ...201121709438
plant lipid transfer protein allergens: no cross-reactivity between those from foods and olive and parietaria pollen.background: cross-reactivity among plant food allergens belonging to the nonspecific lipid transfer protein (ltp) family is well known. in contrast, the relationship among these allergens and their putative homologs from olive (ole e 7) and parietaria (par j 1) pollen has not been clarified. methods: sera with specific ige to ltp allergens were obtained from peach-, mustard- and olive pollen-allergic patients. purified ltp allergens from foods (peach, apple, mustard and wheat) and pollens (olive ...201121720174
changing pattern of sensitization in croatia to aeroallergens in adult population referring to allergy clinic during a period of 15 years.published data indicate that during the last decades there is a possible change in the pattern of sensitization to different aeroallergens in adult population with atopy. the aim of this investigation was based on the hypothesis that during last 15 years there has been a change in the structure of prevalence of sensitization to different aeroallergens in adult population of zagreb and its surroundings with atopy. medical records from outpatient allergy clinic were screened for the period 1991-20 ...201121755728
actions of artemisia vulgaris extracts and isolated sesquiterpene lactones against receptors mediating contraction of guinea pig ileum and trachea.aim of the study: the present study evaluates the philippine medicinal plant artemisia vulgaris for antagonistic activity at selected biogenic amine receptors on smooth muscle of the airways and gastrointestinal tract in order to explain its traditional use in asthma and hyperactive gut. materials and methods: the antagonistic activity of chloroform crude extract (av-chcl(3)) and methanol crude extract (av-meoh) of artemisia vulgaris was studied against concentration-response curves for contract ...201121762766
is the strange case of mugwort sensitivity in ragweed-allergic subjects coming eventually to a solution? 201121789966
influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in chinese allergic patients.the association between sensitizations and severity of allergic diseases is controversial.201121831329
[allergies in summer].summertime allergic symptoms include sneezing, running and stuffy nose, burning and itching eyes and wheal formation on the skin. in finland the problems in allergic people during the spring and summer are mainly associated with the pollen of birch, alder, hazel, grasses and mugwort. the efficacy of drugs used for the treatment of seasonal allergic rhinitis varies. treatment is usually initiated with a non-sedating antihistamine, and nasally sprayable corticosteroids can be used if the symptoms ...201121834339
[incidence of microsporidian infection of stem borers of the genus ostrinia (lepidoptera: crambidae) in the krasnodar territory].infection of corn borers of the genus ostrinia with microsporidia is found for the first time in russia. incidence rates of the last instar larvae of the second generation, sampled under natural conditions in the krasnodar territory, is ranged between 3.0 and 17.2%. when infection incidence rates have been compared between larvae, collected (a) on the western and eastern borders of the region and (b) on dicotyledonous (cocklebur, mugwort) and monocotyledonous plants (maize), no distinct differen ...201121874854
Spice allergy.To provide a review on spice allergy and its implementation in clinical practice.201121875536
sensitization prevalence, antibody cross-reactivity and immunogenic peptide profile of api g 2, the non-specific lipid transfer protein 1 of celery.celery (apium graveolens) represents a relevant allergen source that can elicit severe reactions in the adult population. to investigate the sensitization prevalence and cross-reactivity of api g 2 from celery stalks in a mediterranean population and in a mouse model.201121897872
polymeric structure and host toll-like receptor 4 dictate immunogenicity of ny-eso-1 antigen in vivo.in search of intrinsic factors that contribute to the distinctively strong immunogenicity of a non-mutated cancer/testis antigen, we found that ny-eso-1 forms polymeric structures through disulfide bonds. ny-eso-1 binding to immature dendritic cells was dependent on its polymeric structure and involved toll-like receptor-4 (tlr4) on the surface of immature dendritic cells in mouse and human. gene gun-delivered plasmid encoding the wild-type ny-eso-1 readily induced t cell-dependent antibody (ab) ...201121900253
[to investigate the effect of pretreatment with budesonide spray in patients with allergic rhinitis].to investigate the effects of prophylactic drugs on allergic rhinitis.201122032120
herbs in epilepsy: evidence for efficacy, toxicity, and interactions.herbs and dietary supplements enjoy widespread use in the treatment of epilepsy although supportive data yielding efficacy and safety are lacking. ten specific products, american hellebore, betony, blue cohosh, kava, mistletoe, mugwort, pipsissiwa, skullcap, valerian, and melatonin, have either multiple-cited recommendations for use in epilepsy or a rationale for antiepileptic action and are discussed in detail. these items paradoxically often have a proconvulsant effect in addition to potential ...201122062945
allergenic lipid transfer proteins from plant-derived foods do not immunologically and clinically behave homogeneously: the kiwifruit ltp as a model.food allergy is increasingly common worldwide. tools for allergy diagnosis measuring ige improved much since allergenic molecules and microarrays started to be used. ige response toward allergens belonging to the same group of molecules has not been comprehensively explored using such approach yet.201122114713
expression of the major mugwort pollen allergen art v 1 in tobacco plants and cell cultures: problems and perspectives for allergen production in plants.an economic and cheap production of large amounts of recombinant allergenic proteins might become a prerequisite for the common use of microarray-based diagnostic allergy assays which allow a component-specific diagnosis. a molecular pharming strategy was applied to express the major allergen of artemisia vulgaris pollen, art v 1, in tobacco plants and tobacco cell cultures. the original art v 1 with its endogenous signal peptide which directs art v 1 to the secretory pathway, was expressed in t ...201122159963
Glycosides of Hydroxyproline: Some Recent, Unusual Discoveries.Glycosides of hydroxyproline (Hyp) in the plant cell wall matrix were discovered by Lamport and co-workers in the 1960s. Since then, much has been learned about these hydroxyproline-rich glycoproteins (HRGPs). The intent of this review is to compare and contrast some less common structural motifs, in non-traditional roles, to uncover themes. Arabinosylation of short peptide plant hormones is essential for growth, cell differentiation and defense. In a very recent development, prolyl hydroxylase ...201122190471
humoral and cellular cross-reactivity between amb a 1, the major ragweed pollen allergen, and its mugwort homolog art v 6.ragweed and mugwort are closely related weeds that represent the major cause of pollen allergy in late summer. concomitant sensitization and clinical cross-reactivity frequently occur in subjects who are coexposed to both pollen species, and have implications for diagnosis and specific immunotherapy. molecules involved in this cross-reactivity might be amb a 1, the major ragweed pollen allergen, and art v 6, a highly homologous allergen from mugwort. therefore, we investigated the ige and t cell ...201222205029
the revised edition of korean calendar for allergenic pollens.the old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes of weather and environment of each region in south korea. a new pollen calendar of allergenic pollens was made based on the data on pollen concentrations obtained in eight regions nationwide between 1997 and 2009. the distribution of pollen was assessed every day at 8 areas (seoul, guri, busan, daegu, jeonju, kwangju, kangneung, and jeju) for 12 years between july 1, 1997 ...201222211164
oral administration of allergen extracts from mugwort pollen desensitizes specific allergen-induced allergy in mice.clinically, sublingual immunotherapy (slit) using allergen extracts effectively alleviates the symptoms of allergic rhinitis and asthma. we hypothesized that oral administration of a high-dose of allergen extracts imitates slit, which may prevent ige-related responses in allergic diseases. in the present study, we investigated the effects of oral administration of allergen extracts from mugwort pollen (mp) on allergen-induced inflammation and airway hyperresponsiveness (ahr) in an allergic mouse ...201222240342
[prevalence of sensitization to aeroallergens in 10 030 patients with allergic rhinitis].to investigate the main inhaled allergens in patients with allergic rhinitis.201122335978
[clinical analysis of allergic rhinitis in children between 1 and 3 years of age].to study the atopy spectrum and its related factors in 1 to 3 years old children with allergic rhinitis.201122335979
structural glycobiology of the major allergen of artemisia vulgaris pollen, art v 1: o-glycosylation influence on the protein dynamics and allergenicity.art v 1 is the major allergen of mugwort (artemisia vulgaris) pollen. it is formed by an n-terminal globular defensin-like part and a c-terminal proline-rich domain. as the structure and the dynamics of art v 1 have been mostly described for its recombinant, non-glycosylated form, which does not occur in normal plant physiology, the present work intends to obtain a three-dimensional model for art v 1 native o-glycosylation structure and to evaluate the influence of such glycans over the protein ...201222367746
[a cohort investigation of the allergen and pathogenesis in the patients with allergic rhinitis from three hospital of guangdong province].to study the pathogenesis of the patients with allergic rhinitis diagnosed by skin prick test (spt), especially about the epidemiologic data of the involved allergens.201122384564
ige reactivity patterns in patients with allergic rhinoconjunctivitis to ragweed and mugwort pollens.differential diagnosis between ragweed and mugwort pollen allergy represents a large clinical problem in areas where both plants are present. the aim of this study was to investigate ragweed- and mugwort-sensitized patients to identify specific ige reactivity profiles. results were correlated to clinical findings such as medical history and health-related quality of life (hrql).201222391077
specific ige measurement using advansure® system: comparison of detection performance with immunocap® system in korean allergy patients.advansure enzyme immunoassay (eia) system is a recently developed multiple allergen screen test with specific immunoglobulin e (sige) detection assay, while immunocap fluorescent eia (feia) has been widely used for sige detection. there has been no inter-assay comparison data for these two systems. we determined the detection performance of advansure system compared to that of immunocap.201222394454
[evaluation of exposure and sensitization to house dust mites among rhinitis patients in the steppe environment of inner mongolia].to evaluate the correlation of exposure and sensitization to house dust mites among rhinitis patients, and the consistency of skin prick test (spt) and serum specific ige (sige) in the detection of sensitization in a steppe environment of inner mongolia.201222455768
a geochemical study of toxic metal translocation in an urban brownfield wetland.rhizosphere soil and dominant plant samples were collected at a brownfield site in new jersey, usa, during summer 2005 to evaluate plant metal uptake from the contaminated soils. metal concentrations varied from 4.25 to 978 μg g(-1) for as, 9.68-209 μg g(-1) for cr, 23.9-1870 μg g(-1) for cu, and 24.8-6502 μg g(-1) for zn. a wide range of metal uptake efficiencies in the roots, stems and leaves was found in this study. data showed that (1) betula populifolia has high zn, cu and as accumulations ...201222459711
[pollen allergy and immunotherapy].pollinosis affects up to 25 % of the swiss-population and increased substantially during the last century. main causative pollens are birch and related pollens, ash pollen and grass pollen and to a lesser extent also mugwort. diagnosis of pollinosis is based on anamnesis, skin tests and determination of specific ige in the serum. treatment includes allergen avoidance, pharmacotherapy and allergen-specific immunotherapy (sit). a proper patient and allergen extract selection, an ideally adapted ap ...201222477663
experimental studies on artemisia vulgaris - a possible antifertility drug.the effect of alcoholic extract of the aerial parts of artemisia vulgaris linn on estrous cycle and implantation, in female albino rats, was studied. the drug induced an irregular estrous cycle with random disappearance of estrous phase and increase in the number of metestrus phases within the estrous cycle, observed for the total test period of 18 days. it exhibited 80% anti-implantation activity without showing any gross malformations in pups delivered, possibly due to its non-toxic nature eve ...199422556669
sensitization to common ragweed in southern bavaria: clinical and geographical risk factors in atopic patients.sensitization to common ragweed (ambrosia artemisiifolia) is associated with a variety of risk factors, which are incompletely defined. our aim was to evaluate the association of a variety of clinical, geographical and demographical variables with ragweed sensitization and also to determine its frequency in southern bavaria.201222572962
relationship between total tear ige and specific serum ige in autumnal allergic conjunctivitis.a new commercial immunochromatographic test (allerwatch) has recently been developed for determining total immunoglobulin e (ige). we previously reported on the use of this kit for analyzing tear fluid samples collected during the spring. in this study, we examined the relationship between the total ige level in tears and the specific serum ige levels in patients with autumnal allergic conjunctivitis.201322580438
patients with oral allergic syndrome to apple have intense proliferative response to bet v 1.patients with pollen allergy may frequently present an additional food-related allergy (oral allergic syndrome, oas), as consequence of cross-reactivity between pollen allergens (mainly birch, hazelnut, alder, mugwort) and vegetable allergens. the aim of this study was to evaluate the effect on bet v 1-induced t cell proliferation exerted by the presence of oas in birch patients. fourteen allergic patients were evaluated (6 males, mean age 35.8 years). all of them were monosensitized to birch an ...201222691258
composition of the essential oil of wild growing artemisia vulgaris from erie, pennsylvania.essential oil from wild growing artemisia vulgaris l. originating in erie, pennsylvania was obtained by hydrodistillation of the aerial parts of the plant. gas chromatographic-mass spectral analysis was used to identify the major volatiles present. up to 22 components were detected in the essential oils. germacrene d (25%), caryophyllene (20%), alpha-zingiberene (15%) and borneol (11%) represent the major components of leaf oil, while the buds were rich in 1,8-cineole (32%), camphor (16%), borne ...201222799096
plant food allergy in patients with pollinosis from the mediterranean area.patients with pollinosis develop symptoms after intake of plant food more often than the general population. in order to study the prevalence of the presentation of allergic symptoms to plant foods in pollinosis, we selected a representative sample of the population from our mediterranean area.201222832505
association of hla-dr1 with the allergic response to the major mugwort pollen allergen: molecular background.mugwort pollen allergens represent the main cause of pollinosis in late summer. the major allergen, art v 1, contains only one single immunodominant, solely hla-dr-restricted t cell epitope (art v 125-36). the frequency of hla-drb1*01 is highly increased in mugwort-allergic individuals and hla-dr1 serves as restriction element for art v 125-36. however, art v 125-36 also binds to hla-dr4 with high affinity and dr1-restricted art v 125-36 -specific t cell receptors can be activated by hla-dr4 mol ...201222871092
fumigant toxicity of plant essential oils against camptomyia corticalis (diptera: cecidomyiidae).the toxicity of 98 plant essential oils against third instars of cecidomyiid gall midge camptomyia corticalis (loew) (diptera: cecidomyiidae) was examined using a vapor-phase mortality bioassay. results were compared with that of a conventional insecticide dichlorvos. based on 24-h lc50 values, all essential oils were less toxic than dichlorvos (lc50, 0.027 mg/cm3). the lc50 of caraway (carum carvi l.) seed, armoise (artemisia vulgaris l.), clary sage (salvia sclarea l.), oregano (origanum vulga ...201222928313
radioactive pollution from fukushima daiichi nuclear power plant in the terrestrial environment.major contaminants from venting and hydrogen explosions at the fukushima daiichi nuclear reactors between 12 and 15 march 2011 were transported northwestward and deposited on soil and plants via precipitation. surface soils and plant leaves were sampled at 64 sites in the fukushima prefecture. the highest concentrations of (134)cs (84.4 kbq kg(-1)) and (137)cs (82.0 kbq kg(-1)) in surface soils were observed at nagadoro in iidate village located 32 km northwest from the fukushima daiichi nuclear ...201222933410
peach allergy in china: a dominant role for mugwort pollen lipid transfer protein as a primary sensitizer. 201322939759
combination of multiple resistance traits from wild relative species in chrysanthemum via trigeneric hybridization.with the objective of combining multiple resistant traits from wild relative species in florist's chrysanthemums, trigeneric hybridization was conducted by crossing two intergeneric f(1) hybrids chrysanthemum grandiflorum × artemisia vulgaris and chrysanthemum crassum × crossostephium chinense.201222952958
lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant-foods and pollens.multiple plant-food sensitizations with a complex pattern of clinical manifestations are a common feature of lipid transfer protein (ltp)-allergic patients. component-resolved diagnosis permits the diagnosis of the allergen sensitization profile.201222994350
increased allergic sensitization to mugwort in chronic urticaria.mugwort pollen is known to cross-react with a variety of spices and vegetables that are typically part of elimination diets used in the treatment of chronic urticaria (cu).201223018776
sensitization rates of airborne pollen and mold in children.aeroallergens are important causative factors of allergic diseases. previous studies on aeroallergen sensitization rates investigated patients groups that had visited pediatric allergy clinics. in contrast, we investigated sensitization rates in a general population group of elementary school to teenage students in incheon, jeju, and ulsan.201223049589
[clinical significance of skin prick test for inhalant allergens in 3085 children with allergic diseases].to investigate the main inhalant allergens and their distribution patterns in children with allergic diseases from xi'an and the surrounding area and to provide evidence for the prevention and treatment of allergic diseases in children.201223092566
[investigation of skin prick test on 2707 patients with allergic rhinitis in wuhan area].to investigate the distribution of common allergens in patients with allergic rhinitis (ar) from 2006 to 2010 in wuhan area, and provide the objective evidence for the prevention and treatment of ar.201223141402
larvicidal activity against aedes aegypti of essential oils from northeast brazil.the larvicidal activities of essential oils from the leaves of artemisia vulgaris l., cymbopogon flexuosus (nees ex steud.) wats. and piper tuberculatum jacq. were evaluated using third-instar larvae of aedes aegypti. the essential oils were obtained by hydrodistillation and analyzed by gc and gc-ms. the essential oil of p. tuberculqatum had the lowest lc50 value (106.3 +/- 2.2 microg/ml), followed by that of a. vulgaris (114.1 +/- 1.7 microg/ml) and c. flexuosus (121.6 +/- 0.8 micro/ml). the re ...201223157019
jaceosidin, isolated from dietary mugwort (artemisia princeps), induces g2/m cell cycle arrest by inactivating cdc25c-cdc2 via atm-chk1/2 activation.jaceosidin, a flavonoid derived from artemisia princeps (japanese mugwort), has been shown to inhibit the growth of several human cancer cells, however, the exact mechanism for the cytotoxic effect of jaceosidin is not completely understood. in this study, we investigated the molecular mechanism involved in the antiproliferative effect of jaceosidin in human endometrial cancer cells. we demonstrated that jaceosidin is a more potent inhibitor of cell growth than cisplatin in human endometrial can ...201323274058
effect of pollen-specific sublingual immunotherapy on oral allergy syndrome: an observational study.: oral allergy syndrome (oas) triggered by fruit and vegetables often occurs in patients with pollen-induced rhinoconjunctivitis because of cross-reactive epitopes in pollen and associated foods. this open observational study examined the effect of pollen-specific sublingual immunotherapy ([slit] b. u. pangramin or slitone involving birch/alder/hazel, grasses/rye, and/or mugwort) on oas triggered by several foods in patients treated in standard practice. very few studies have examined slit use i ...200823282323
allergy diagnosis in children and adults: performance of a new point-of-care device, immunocap rapid.: allergy is a serious problem affecting approximately 1 of 4 individuals. the symptoms with and without allergy etiology are often difficult to distinguish from each other without using an ige antibody test. the aim of this study was to investigate the performance of a new point-of-care (poc) test for ige antibodies to relevant allergens in europe.200923283063
dietary intervention for oral allergy syndrome as a treatment in orofacial granulomatosis: a new approach?orofacial granulomatosis (ofg) is a chronic granulomatous condition of the mouth, face and lips. recent work demonstrates a high rate of atopy and silver birch sensitisation from skin prick testing (spt). oral allergy syndrome (oas) is an acute oro-pharyngeal ige mediated reaction, triggered by foods that cross react with pollens, most commonly silver birch. the aim of this study was to determine if patients with ofg and positive spt to common oas associated pollens responded to avoidance of cro ...201323297760
inhibitory effect of cinnamon powder on pathogen growth in laboratory media and oriental-style rice cakes (sulgidduk).there has been an increasing interest in the use of natural plant materials as alternative food preservatives. we examined the antimicrobial effects of natural plant materials used as additives against foodborne pathogens in laboratory media and sulgidduk, oriental-style rice cakes. cinnamon, mugwort, and garlic powder solutions (3%) were tested for their antimicrobial activities against pathogens in laboratory media. sulgidduk prepared with different amounts of cinnamon powder (1, 3, and 6%) wa ...201323317869
the skin prick test - european standards.skin prick testing is an essential test procedure to confirm sensitization in ige-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. this manuscript reviews the available evidence including medline and embase searches, abstracts of international allergy meetings and position papers from the world allergy literature. the recommended method of prick testing includes the appropriate use of specific allergen extract ...201323369181
identification of plant extracts sensitizing breast cancer cells to trail.triple-negative breast cancer (tnbc) is an aggressive heterogeneous cancer subgroup with a higher rate of distant recurrence and a poorer prognosis compared to other subgroups. tumor necrosis factor-related apoptosis-inducing ligand (trail) is an attractive molecule that induces cell death in various tumor cells without causing cytotoxicity to normal cells; however, primary or acquired resistance to trail often limits its efficacy in cancer patients. to develop combination therapies to improve t ...201323426404
prevalence of sensitization to weed pollens of humulus scandens, artemisia vulgaris, and ambrosia artemisiifolia in northern china.weed pollens are common sources of allergens worldwide. the prevalence of weed pollen sensitization is not yet fully known in china. the purpose of this study was to investigate the prevalence of sensitization to weed allergens from artemisia, ambrosia, and humulus in northern china.201323463767
from soil to leaves--aluminum fractionation by single step extraction procedures in polluted and protected areas.the paper presents the fractionation of aluminum in the samples of soil and plants of different species using a selective single-step extraction method. the study was conducted in the area located near a chemical plant, which for many years served as a post-crystallization leachate disposal site storing chemical waste (sector i), and in the area around the site: in wielkopolski national park, rogalin landscape park and toward the infiltration ponds at the "dębina" groundwater well-field for the ...201323651943
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