Publications

international colloquium on basic health services in developing countries. antwerp, belgium, 8-10 december 1978.		1994	45072
interactions of pharmacological agents which alter biogenic amine metabolism and depression--an analysis of contributing factors within a primate model of depression.	the observation that the biogenic amine depleting agent, reserpine, could induce severe depression in a small proportion of the patients treated with it has proved to be seminal finding in what is now a much larger field of research relating the function brain biogenic amine systems to emotions and behavior. a review of the human reserpine literature suggests, however, that factors other than pharmacologically produced alterations in brain biogenic amine metabolism must have been critical determ ...	1979	45183
emergence of antibiotic resistance in hospitals, 1935-1975.	a limited review of the changes in susceptibility of common bacterial pathogens to available antibacterial agents is presented. significant developments in recent years include the following: (1) the emergence of streptococcus pneumoniae with decreased resistance to penicillin and of some strains resistant to several antibiotics; (2) a decline in prevalence of multi-drug-resistant staphylococcus aureus after 1960 following their increasing prevalence in the preceding years (these changes were me ...	1979	45521
a comparison of staphylococcal nasal carrier rates in germany and poland.	frequencies of different staphylococcal nasal carrier classes were studied in groups of students of nursing and of laboratory personnel in cologne, west germany, and in krakow, poland, by six consecutive samplings of their nasal vestibules. the general number of persistent carriers of s. aureus appeared to be lower than in previous studies, paralleling the diminished numbers of staphylococcal infections in populations. differences in numbers of persistent carriers between the cologne and krakow ...	1978	45603
hypotension in hepatic failure.		1993	46440
letter: risk of transfusing blood containing anti-hbs.		1993	46488
letter: in-vitro minocycline activity against tetracycline-resistant staphylococcus aureus.		1975	46562
the genetic defect in galactosemia.		1993	46587
effect of microwaves on cell function and virus replication in cell cultures irradiated in vitro.		1975	46732
sulfhydryl-dependent thermal aggregation of human gamma globulin: augmentation by hyaluronic acid.	hyaluronic acid (4 mg/ml) augmented elevenfold the copper-catalyzed (7 mum) thermal (63 degrees c, 2 hours) aggregation of human gamma globulin (2 mg/ml) in 0.075 m phosphate buffer, ph 7.4. almost no augmentation of aggregation occurred with hyaluronidase-treated hyaluronate. hyaluronate-augmented copper-catalyzed thermal aggregation was inhibited by l-histidine, gold thiomalate, n-ethylmaleimide, p-chloromercuribenzoic acid, and ethylenediaminetetraacetic acid. together with previous reports o ...	1975	46754
fine structure and distribution of extracellular polymer surrounding selected aerobic bacteria.	the structure and distribution of extracellular polymer surrounding bacillus circulans, diplococcus (streptococcus) pneumoniae, streptococcus salivarius, staphylococcus aureus, klebsiella pneumoniae, pseudomonas aeruginosa, herella vaginacola (acinetobacter calcoaceticus), and agrobacterium tumefaciens were studied by electron microscopy. a modified ruthenium red staining procedure was used to examine the fine structure of capsule and slime. freeze-etching and critical-point drying were used to ...	1975	46774
letter: in-vitro minocycline activity against tetracycline-resistant staphylococcus aureus.		1975	47049
letter: minocycline activity against tetracycline-resistant staphylococcus aureus.		1975	47564
immunocytological methods for the identification and localization of antigens.	immunocytologic techniques allow the study of antigenic cellular constituents by optical or electron microscopy, antibodies labelled with tracers such as fluorochromes, enzymes, radioactive isotopes, or large electron-dense molecules form the basis of these techniques. the immunochemical procedures involved in the preparation of such conjugates are well defined. satisfactory results, however, also depend upon the proper preparation and processing of the tissue or cell suspension being studied.	1975	47687
virulence of genus staphylococcus. iii. studies on the pathogenicity to mice.	six representative strains of staphylococci were selected on the basis of dnase activity and inoculated into the mice to study the correlation of the presence of this enzyme to the virulence of the staphylococci. two strains of staphylococci among them produced dnase but not the free coagulase, and one of these two strains had an obvious virulence against the mice. the results of experiments suggest that there are at least certain strains which may be designated as staphylococcus aureus among th ...	1975	47790
enhanced bactericidal activity of phagocytes from patients with chronic granulomatous disease in the presence of sulphisoxazole.	the decrease in the frequency and severity of bacterial infections in four of five children with chronic granulomatous disease (c.g.d.) on long-term sulphonamide therapy was out of proportion to demonstrable direct antibacterial effects of the drug. in an attempt to determine the mechanism for this apparent protective effect, the killing of sulphisoxazole-resistant escherichia coli and staphylococcus aureus by leucocytes from five patients with c.g.d. was studied in the presence or absence of 5- ...	1975	48055
letter: intestinal lymphocytes in crohn's disease.		2001	48148
letter: chronic low-level leaf exposure and mental retardation.		2001	48160
emergency! part 3: on-the-spot care for aspiration, burns, and poisoning.		1975	48222
[hoigner's reaction and its diagnostic value in acute dysentery].		1992	48594
phagocytosis in patients and carriers of chronic granulomatous disease.	the phagocytic capacity of leucocytes from four patients and two carriers of chronic granulomatous disease (c.g.d.) was compared to that of normal leucocytes. leucocytes from c.g.d. patients phagocytised more staphylococcus aureus than did normal leucocytes after 5, 10, and 20 minutes of incubation. phagocytosis by leucocytes from two carriers of c.g.d. was intermediate between that in the patients and in controls. in contrast, phagocytosis of streptococcus faecalis, an organism readily killed b ...	1975	48723
letter: d-penicillamine-induced membranous glomerulonephritis.		1992	48830
a radioimmunoassay of cellular surface antigens on living cells using iodinated soluble protein a from staphylococcus aureus.	soluble protein a from staphylococcus aureus does carry great promise as a marker for cellular surface determinants, due to its specific reaction with, and high affinity for, most subclasses of mammalian igg. in this article we present the different parameters involved in a radioimmunoassay using 125-i-labelled protein a. using such an approach the actual technical procedures involved are reported in detail together with tests for mammalian alloantigens, including hl-a in the human, h-2 in the m ...	1975	49379
editorial: somatostatin and diabetes.		1992	49521
staphylococcus aureus transmitted in transplanted kidneys.	staphylococcus aureus septicaemia developed shortly after transplantation in both recipients of transplanted kidneys from a donor who had received electrical burns. in each case the organism appeared initially in the urine. all staphylococci isolated were phage type 6/47/54/75. transplant nephrectomy was necessary in both recipients because of complications of infection, and one recipient died. these results draw attention to the possible significance of staph. aureus in the urine of recipients ...	1975	49795
induction of histamine release and densensitization in human leukocytes.	protein a from staphylococcus aureus has been found to react with all human leukocyte preparations tested. in 70 percent of the experiments the reaction leads to histamine release. furthermore, protein a treatment of cells at 37 degrees c, both in complete and ca-2+-free medium, results in the inhibition of anti-ige-induced histamine release in all cell preparations, indicating that protein a and anti-ige antibodies release histamine from the same cells. this inhibition seems to be due to the bl ...	1975	49918
microtubules and axonal transport. introductory remarks.		1992	50032
retinal and pigment epithelial alterations over choroidal malignant melanomas.	although in some cases orange or yellow-orange pigment overlying a malignant choroidal melanoma may represent lipofuscin, a case is presented which showed extensive yellow-orange coloration overlying a malignant choroidal melanoma without any demonstrable lipofuscin on histopathologic and electron microscopic analysis. our findings suggest that other mechanisms, such as serous fluid or lipid deposition within retinal cystoid spaces or diffuse drusen, can clinically stimulate the yellow-orange pi ...	1992	50039
concealed ventricular extrasystoles due to interference and due to exit block.	two cases of sinus rhythm with ventricular extrasystoles are reported in which extrasystoles arising from the same focus obey the rule of "comcealed bigeminy" and the "rule of bigeminy". in a comparatively rapid sinus rhythm, shortening of the sinus cycle favors the appearance of extrasystoles, and the extrasystoles obey the fule of "concealed bigeminy"; namely, sinus impulses intervene between extrasystoles in even numbers. the sinus impulses here include those both conducted and not conducted ...	1992	50154
immunochemical analysis of a smith-like antigen isolated from two human strains of staphylococcus aureus.	a surface antigen consisting of aminoglucuronic acid and n-acetyl-l-alanine was isolated from the culture filtrates of two human strains of staphylococcus aureus. double diffusion analysis in agar suggested that the antigen is immunologically similar to the alanyl-aminoglucuronic acid capsule of the smith strain of s. aureus. quantitative precipitin inhibition studies indicated that n-acetyl-l-alanine is the immunodominant determinant of the acidic antigen. in addition, conjugates consisting of ...	1975	50368
staphylococcal food poisoning aboard a commercial aircraft.	on feb. 3, 1975, 196 (57%) of 344 passengers and 1 steward aboard a commercial aircraft contracted a gastrointestinal illness characterised by nausea, vomiting, abdominal cramps, and diarrhoea; 142 passengers and the steward were admitted to hospital. symptoms developed shortly after a ham and omelette breakfast had been served. an investigation strongly incriminated ham as the vehicle of the outbreak, and the source seems to have been a cook with lesions on his fingers. the attack-rate was 86% ...	1975	51419
[primary malignant tumors of the biliary tract (author's transl)].		1991	51571
new familial defect in microbicidal function of polymorphonuclear leucocytes.	a family is described in which a defect in intracellular killing affected two, and probably three, siblings of both sexes. from an early age they have had recurrent severe infections. during these episodes their white-blood-cell count became very high. this familial disorder seems to differ from previously reported syndromes of abnormal leucocyte function.	1975	52003
methicillin-resistant staphylococci 1965-75.	methicillin resistance in staphylococcus aureus has been one of the major problems of gram positive infections in hospitals in the zurich area. up to 1971, about 20% of staphylococcal disease was caused by these peculiar organisms. since 1972, however, a gradual decrease in the number of methicillin-resistant organisms has been observed, with an unprecedented low of 3% in 1975. the nearly 700 methicillin-resistant cultures that have isolated since 1965 exhibited, with rare exceptions, convention ...	1975	52016
letter: diagnosis of g.-6-p.d. deficiency.		1991	52023
[serological studies on staph. aureus strains from various processes of a disease of human origin (author's transl)].	this paper deals with serological studies on 332 staph. aureus strains of human origin having been isolated from various sources. on the basis of typing with 17 factor sera, a great number of groups and types was obtained occurring among the strains of several processes of a disease without showing special serological structural formulae which would have been typical for pathological changes of certain localisation. but still deviations have been observed between the strains of most of the serie ...	1975	52246
stains for six enzymes potentially applicable to chromosomal assignment by cell hybridization.		1991	53126
proteoglycans in primate arteries. i. ultrastructural localization and distribution in the intima.	proteoglycans were identified and localized histochemically and ultrastructurally in normal and hyperplastic arterial intimas in nonhuman primates (macaca nemestrina). these regions were consistently more alcianophilic than the adjacent medial layers and this alcianophilia was absent after treatment with glycosaminoglycan-degradative enzymes. ultrastructurally, the intimal intercellular matrix consisted of numerous, irregularly shaped, 200-500-a diameter granules possessing 30--60-a diameter fil ...	1990	53234
partial characterisation of an inhibitor of streptolysin o produced by bacterial growth in serum.	an inhibitor of streptolysin o is generated in human and animal sera by the growth of certain organisms. the ability to do this occurs most often in pseudomonas aeruginosa and staphylococcus aureus (in 90% and 86% of strains respectively), but in only 32% of staph. epidermidis strains. the inhibitor is not formed in broth. the effect appears slowly on incubation, with maximum activity after 4-7 days. evidence suggests that two enzymes are involved, an esterase which splits ester-bound cholestero ...	1975	54429
gentamicin resistance in staphylococcus aureus.	a clinical isolate of staphylococcus aureus was resistant to gentamicin, kanamycin, and tobramycin by virtue of the production of a drug-inactivating enzyme. attempts to establish the cellular location of the genetic determinants for enzyme synthesis have given equivocal results.	1976	54520
letter: ampicillin resistance in staphylococci.		1976	54715
the influence of phosphatidyl serine on the release of histamine from isolated rat mast cells induced by different agents.	the influence of phosphatidyl serine (ps) on histamine release from isolated rat mast cells induced by antigen, compound 48/80, adenosine-5'-triphosphate (atp), the ionophore a23187, and decylamine was studied. ps enhanced antigen-induced release but inhibited the release caused by compound 48/80, a23187, and decylamine. ps did not influence the release induced by atp. the different effects of ps on the action of the various histamine releasing agents do not conform to a unifying model for the a ...	1975	55064
cell-mediated immune response in mice treated with steroidal contraceptives.	the splenomegaly assay (simonsen, 1962) was standardized using different strains of rats and mice. male wistar rat (donor)-female swiss mouse (host) was found to be the suitable combination that could be employed in subsequent experiments to study the potential of contraceptive steroids to alter cmir. the index of splenomegaly appeared to increase in case of mice treated with combination oral contraceptives (ovulen, ovral or enovid). the differences observed, however, neared significance only in ...	1975	55327
the effect of various contraceptive hormonal therapies in women with normal and diabetic oral glucose tolerance test.	the effect of various contraceptive hormonal therapies was studied in 176 women with normal and diabetic oral glucose tolerance tests (ogtts). 160 women showed normal and 16 showed diabetic patterns on the 14th day of a control cycle, during the 3rd and 6th months of contraceptive therapy, and 3 months after having stopped medication. the women were divided into groups and fitted with a lippes loop, treated with low doses of chlormadinone acetate, lynestrenol, and megestrol acetate or with a seq ...	2001	55331
biological effects of carbon monoxide vs. whole emissions from engine with catalyst.		1976	55426
analysis of cell-surface markers with staphylococcal protein a: fluorescence studies on mammalian lymphoid determinants.	membrane antigens including different classes of immunoglobulins, transplantation antigens, beta2-microglobulin, t lymphocyte specific antigens, and virally determined surface components were investigated using fluorescein-labeled staphylococcal protein a in combination with cytofluorometric studies. lymphocytes of seven species: mouse, rat, guinea pig, pig, cow, monkey, and human, and of ten human lymphoma-derived lines were tested. analysis of the differential expression of surface markers rev ...	1976	55446
letter: reversible decline.		2001	55544
diminished effect of gentamicin under anaerobic or hypercapnic conditions.	the in-vitro activity of gentamicin, judged by m.i.c. determinations, was much reduced when a normal aerobic atmosphere was replaced either by air +4% co2 or by anaerobic conditions. the phenomenon was greatest for staphylococcus aureus, where a decrease in activity of up to 20-fold was found. for escherichia coli, klebsiella aerogenes, enterobacter spp., and proteus spp. the factor of decrease was between 15-fold and 2-5-fold. changes in medium ph, as a result of bacterial growth, can explain t ...	1976	55718
epidemic infection by a gentamicin-resistant staphylococcus aureus in three hospitals.	a staphylococcus aureus strain, resistant to aminoglycosides, including gentamicin and tobramycin, and to penicillin, lincomycin, and other antibiotics, caused an outbreak of hospital infection in a surgical ward which spread to the intensive-therapy unit and to two other hospitals. 21 patients were colonised and 9 of these had overt clinical infection. administration of antibiotics to which the staphylococcus was resistant was associated with colonisation. the use of gentamicin, tobramycin, and ...	1976	55729
john clifford hoyle.		2001	55775
letter: "e" antigen.		2001	55805
letter: coeliac disease unmasked by self-challenge with wheat germ.		2001	55911
letter: haematology: origins of an impasse.		2001	55917
[effect of the antistaphylococcal gamma-globulin and its combinations with solafur on penicillinase activity of staphylococci].		1975	55946
induction of histamine release and desensitization in human leukocytes.	histamine release from normal human leukocytes can be induced by anti-ige or protein a from staphylococcus aureus. after incubation in buffer at 37 degrees c for various time intervals or repeated washings with buffer, or both procedures, the leukocytes lose most of their reactivity to protein a, whereas the reactivity to anti-ige is unaltered. cells deprived of their protein a reactivity can be induced to release histamine by igg complexed with protein a. maximal release (23%-81%) from 0.6-1.0 ...	1975	56030
[cytotoxic effects of a leukocidin from staphylococcus aureus (author's transl)].	in an attempt to improve the assay of leukocidin from staphylococcus aureus a combined vital fluorochrome staining procedure with acridine organe and ethidium bromide was developed. it proved to be more suitable for the demonstration of leukocidic effects on leukocytes than phasecontrastmicroscopy. damaged leukocytes fluoresced distinctly red and undamaged leukocytes green. with the fluorochrome-method leukocidic changes became also evident in some lymphocytes. these were not clearly demonstrate ...	1975	56107
fetal syphilis in the first trimester.	evidenc of first-trimester fetal syphilis was sought in the products of conception in a therapeutic abortion clinic. during two collection periods of one week, five patients with serologic and clinical data consistent with recent syphilitic infection were identified. their conceptuses were carefully examined by silver and immunofluorescent stains for the presence of treponema pallidum. two of these five conceptuses (9 and 10 weeks' gestation) were found to contain t. pallidum by these methods. t ...	1976	56895
[tachycardia caused by reciprocal rhythm between normal pathways and a rapid atrial-his pathway].	report of one unhabitual case of reciprocal rhythm with anterograde conduction through james' fibres and retrograde conduction through the normal nodal pathways. the reality of an anterograde nodal short-circuit is indicated by many arguments, and in particular by the presence of a double ventricular response, after induced atrial premature beats reaching the ventricle once by the rapid pathway and the second time by the slow pathway.	2001	56925
release of the carcinogen benzo (a) pyrene from environmentally contaminated mussels.		2001	56966
retrograde axonal transport of antibody to dopamine-beta-hydroxylase.		1976	56975
automatic gram-staining with the microstainer ii.	a comparison was made between the microstainer ii, an automatic staining machine, and the traditional, manual gram-staining method using clinical material and known organisms in a double blind study. gram-reactions were in agreement with 98.4% of the organisms. the machine-stained microorganisms were generally found to be of the same or better quality than manually-stained organisms. transfer of bacteria from slide to slide or smear to smear was not a significant problem. the microstainer ii wou ...	1976	57106
effects of hypothalamic lesions on levels of plasma free fatty acids in the mallard duck.	plasma free fatty acid (ffa) levels were measured in the mallard duck (anas platyrhynchos) following hypothalamic lesions at various sites. the results indicate that ventromedial lesions produced hyperphagia, increased deposition of fat, and significantly elevated levels of plasma ffa. anterior bilateral lesions resulted in aphagia, severe loss in body weight and a marked decrease in plasma ffa. lesions in other regions of the hypothalamus produced various changes depending upon the extent of d ...	1975	57744
a serial study of pregnancy proteins in primigravidae.	the plasma concentrations from four 'pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. two of the proteins, human placental lactogen (hpl) and pregnancy-specific beta1-glycoprotein (psbetag), are specific for pregnancy and correlate well with the stage of gestation. it is suggested that measurement of psbetag may be useful in assessing feto-placental wellbeing. neither of the pregnancy-associated proteins, steriod-binding beta-globulin (s ...	1976	57799
current questions on the tumour-associated antigens of chemically-induced tumours ii. in search of practical uses.	with special reference to tumours which were chemically-induced in animals, we present a brief review on the applicability of the results obtained, as to immunoprophylaxis and to immunotherapy. a search is made onto what are the mostly representative animal models for human studies. from the present available data, experimental chemically-induced bladder and colonic tumours seem to be the "best" models for human counterparts.	1976	57809
method for identifying salmonella and shigella directly from the primary isolation plate by coagglutination of protein a-containing staphylococci sensitized with specific antibody.	a technique is described that allows presumptive identification of either salmonella or shigella organisms directly upon the original isolation plate, in this case, macconkey agar. this was accomplished by applying a drop of specifically sensitized protein a-containing staphylococcus aureus over a "suspected" colony or several colonies of organisms grown on macconkey agar. the plate is tilted to and fro to allow mixing of the particles with specific antigen that ir readily solubilized from the c ...	1976	57969
[electron microscopic investigations on encapsulated staphylococci (author's transl)].	attempts were made to study the surface of encapsulated staphylococci by electron microscopy. after fixation with osmium tetroxide the encapsulated staphylococci showed a "hazy" cell-surface, possibly because of capsular components (fig. 1). on the other hand, the nonencapsulated staphylococci exposed a "smooth" surface of the cell wall (fig 1). similar findings were obtained after the immuneferritintechnique (fig 2). the staphylococcal capsules could be clearly demonstrated by the "negative con ...	1976	58503
enzymatic synthesis of 5-azacytidine 5'-triphosphate from 5-azacytidine.		2001	58569
specialized junction in the distal convoluted tubule of rat kidney.	the ultrastructure and permeability of the apical junctions between epithelial cells of the distal nephron have been studied in rat kidney using a collidal lanthanum tracer and uranyl acetate staining en bloc. the apical intercellular junctions of the macula densa and juxtaglomerular segment of the early distal convoluted tubule measure up to 0.5 mu in length and about 50 a in width. lanthanum permeates the occluding portion of these junctions in a discontinuous manner, defining a series of clos ...	1976	58570
[application of microcalorimetry to enzyme kinetic studies].		1975	58589
[composition of lipids and proteins of two compounds isolated from infected mice: mouse mammary tumor virus and milk fat globule membrane].		1975	58612
termination of pregnancy by sheep anti-lhrh gamma globulin in rats.	the effect of the administration of sheep anti-lhrh gamma-globulin (anti-lhrhg) on the maintenance of pregnancy was investigated in rats. nidation was confirmed by laparotomy on day 7 or 8 of pregnancy. in one experiment, rats were then injected iv with 1 ml anti-lhrhg or normal sheep gamma-globulin (nsg) daily from days 7 to 11. the uteri were inspected again on day 14 of pregnancy, when it was found that complete resorption of the fetuses had occurred in the anti-lhrhg-treated rats, but that t ...	1976	58780
evaluation of a new technique for the demonstration of gonococci and other micro-organisms in host cells.	a method (gram-mgplg) for demonstrating micro-organisms was compared with gram and four other known methods. each method was tested on tissue infected with staphylococcus aureus, pseudomonas aeruginosa or neisseria gonorrhoeae, which were then fixed in bouin's formol saline, formol sublimate, or van de grift solutions. gram-positive organisms in tissues were easily seen even at low magnification when stained by several of the methods tested. gram-negative organisms, however, are very difficult t ...	1976	58874
an improved method for isolation of h-2 and ia alloantigens with immunoprecipitation induced by protein a-bearing staphylococci.	mouse alloantigens, including the histocompatibility (h-2) and immune response linked (ia) antigen molecules, can be readily isolated by a new precipitation technique utilizing protein a-bearing, fixed staphylococci. the antigens are prepared by radiolabeling mouse spleen cells with 3h-leucine, solubilizing with the non-ionic detergent non-idet p-40, and purifying by affinity chromatography with lentil lectin coupled to sapharose. the antigen preparations are mixed with appropriate alloantisera, ...	1976	58931
letter: alcohol and cancer.		2000	59042
editorial: a wellcome boost.		2000	59084
letter: appendicitis and mimicking conditions.		1999	59109
letter: helping the nomads.		2000	59217
letter: cryo-panagglutinin detected in abo blood-grouping standard sera.		2000	59230
letter: ear, janeu, and heart.		1999	59282
the cutaneous reactions to kallikrein, prostaglandin and thurfyl nicotinate in chronic urticaria and the effect of polyphloretin phosphate.	the erythema and wealing resulting from the application of thurfyl nicotinate ointment (trafuril) and from the inoculation of kallikrein has been studied in patients with chronic urticaria and normal controls. polyphloretin phosphate (ppp) suppressed the reaction in controls but in patients with urticaria it increased the reactions to trafuril and had little effect on the kallikrein reaction. ppp also suppressed the pge2-induced erythma in normal controls but not in urticaria patients. in a sepa ...	1976	59506
deposition of substances within hydrophilic lenses.	one class of hydrophilic lens deposits appears as small, discreted spots under low magnification. higher magnification of cross sections reveals partially crystalline structures which actually extend into the lens matrix. histochemical stains indicate the presence of tear film components within these deposits.	2000	59549
streptozotocin and renal amyloidosis in the syrian hamster.	in the syrian hamster, administration of the drug streptozotocin was associated with an increased incidence and severity of renal amyloidosis. some of the more severely affected animals showed a frankly nephrotic picture. although some of the diseased animals showed decreased levels of serum albumin, no other definite changes in serum proteins were noted, nor was there any evidence of glomerular immunoglobulin or immune complex deposition. none of the lesions previously found after administratio ...	1976	59551
[morphometric analysis of periosteocytic osteolysis: its application to the diagnosis of hyperparathyroidism].	the authors indicate the required methodologic conditions for the morphometric analysis of periosteocytic osteolysis, a reliable and specific feature of overactivity of the parathyroid gland. indeed, significant periosteocytic enlargement has been found in 101 113 cases of primary hyperparathyroidism compared to 92 reference cases. the measurement of the size of the periosteocytic lacunae may be carried out either on hand of a micrometric eyepiece or of a picture analyser. it has to be carried o ...	2000	59559
whodunit (and why). part ii.		2000	59560
research in cystic fibrosis (third of three parts).		1976	59900
kinetics of in vitro bovine keratohyalin synthesis.	a system is described for the study of the in vitro synthesis of bovine keratohyalin for periods of up to 24 h. keratohyalin granules appeared morphologically unaltered during culture, although histochemical stains for rna indicate a markedly diminished rna content by 6 h. incorporation of tritiated histidine began slowly, then became linear between 4 and 24 h in serum-containing media. however, following pre-incubation in serum-free media, increased incorporation occurred from time zero. the in ...	1976	60121
before the drug culture barbiturate/amphetamine abuse in american society.		2001	60195
[characterization of flagella and flagellin of listeria monocytogenes. i. immunological investigations (author's transl)].		1976	60251
letter: behaviour of e antigen and antibody during chronic active liver disease.		2001	60654
letter: gentamicin-resistant staphylococcus aureus.		1976	60662
demonstration of the inhibitory effect of human alpha-fetoprotein on in vitro transformation of human lymphocytes.	we have studied the effects of human alpha-fetoprotein (hafp), isolated from the serum and ascitic fluid of a hepatoma-bearing patient, on the in vitro transformation of human peripheral blood lymphocytes by a variety of mitogenic stimuli. at a concentration of 2.5 mg/ml, hafp inhibited the lymphocyte response to phytohemagglutinin, concanavalin a, and rabbit anti-human thymocyte serum, but failed to inhibit the response to pokeweed mitogen. hafp was able to inhibit the one-way mixed lymphocyte ...	1976	60761
cellular events associated with the immunogenesis of anti-erythrocyte autoantibody responses of nzb mice.		1976	60813
the v gene repertoire as revealed by polyclonal b cell activators.	the evidence for the one non-specific signal hypothesis stating that the b lymphocytes are activated by non-clonally distributed receptors which are not the ig receptors, have been summarized. even though protein a is a polyclonal b cell activator, it does not exert its effect by interacting with the fc part of ig receptors. one consequence of the one non-specific signal concept is that thymus-dependent antigens cannot activate or tolerize b cells. it was shown that b cells from animals tolerant ...	1976	60905
antigenic specificity of cell-mediated antitumor reaction in the msv system.		1975	60997
[increase of resistance to pseudomonas aeruginosa infection in mice caused by staphylococcus aureus].	in our study of opportunistic pathogens, we have some indication that staphylococcus aureus can increase resistance in mice against pseudomonas aeruginosa. intraperitoneal injections of sublethal doses of s. aureus had a protective effect in mice against lethal doses of p. aeruginosa, more so if living and coagulase-positive s. aureus strains were injected. this protective effect was obtained both with laboratory and freshly isolated hospital strains. the interval between these infections can be ...	1976	61060
isolation and characterization of phenotypes of mycobacteria.	several strains of mycobacteria grown as surface pellicle on liquid sauton's medium under semianaerobic conditions dissociated into three phenotypes: phenotypes 1, 2, and 3. only phenotype 1 could be obtained in a pure state. none of these phenotypes was found to be stable: they convert from one into another and all revert to the parental strain when replaced in their usual aerobic cultural conditions. comparative studies of phenotypes 1 and 3 have shown that significant differences exist in the ...	1976	61062
[thyroid gland function tests, ck-t3r and ck-t4r].		2001	61083
investigation of group-specific antigen during the culture of mc-29 hepatoma.	the short-time culture established from mc-29 chicken hepatoma was used for the analysis of cell morphology and expression of avian gs antigen. the content of gs antigen was not changed during the period of cultivation. two morphologically different types of cells were present in tested tumour cells. fluorescent antibody test showed the presence of gs antigen in both types of cells.	1976	61136
[round heart disease in turkeys].		2001	61151
mouse virulent strain of staphylococcus epidermidis. relation of antiphagocytic activity to the protection-inducing antigen.	using 10(9) or 10(7) colony-forming units of a strain of staphylococcus epidermidis (strain 1142) in saline or 5% mucin, respectively, 90 to 100% of mice died within 24 to 48 hr after intraperitoneal challenge infection. these organisms gradually multiplied in the peritoneal cavity when injected intraperitoneally into mice, while the mouse avirulent strain (strain 1124) rapidly decreased and no organisms were found there 20 hr after injection. this strain was capable of inducing resistance again ...	1976	61300