Publications

alpha 1-antitrypsin phenotypes in paraproteinaemias.		1999	85154
[multiple extramedullary plasmacytoma manifesting increased intracranial pressure signs--a case report (author's transl)].		1999	85279
alpha fetoprotein levels in amniotic fluid and maternal serum and their use in screening in pregnancy.	during the period january 1975--july 1977 alpha fetoprotein was measured in 263 amniotic fluid samples and 44 maternal serum samples taken in the second trimester of pregnancy. the importance of careful interpretation of results is discussed.	1999	85285
in vitro sensitization of human t lymphocytes to hapten (tnp)-conjugated and non-treated autologous cells is restricted by self-hla-d.	by co-culturing human t lymphocytes with tnp-treated autologous b lymphocytes and macrophages for 10 days in vitro, sensitization to tnp-treated autologous cells could be detected in a proliferative assay. by restimulation with different types of allogeneic cells and with cells from donors compatible or incompatible for the hla-abc or -d determinants, results were obtained suggesting that the tnp-specific response was restricted by the hla-d but not the -abc antigens of the autologous priming ce ...	1979	85334
[the efficacy of radiohypophysectomy with yttrium 90 in metastatic breast cancer (author's transl)].	radiohypophysectomy in 176 women with metastatic breast cancer, treated over the past 20 years, did not prolong life, but relieved pain in almost half of the patients. this procedure can be carried out quickly and without risk even in severly debilitated patients.	1999	85371
[comparative studies on the demonstrability of eosinophilic granuloma using biebrich's scarlet staining and adam's reaction].		1999	85391
effect of light on the labeling of optic tectum gangliosides after an intraocular injection of n-[3h]acetylmannosamine.		1999	85450
goitrogens.		1979	85506
[relationship of the structure of specific somatic antigen polysaccharides in shigella dysenteriae bacteriae to the immunochemical properties].		1979	85516
eastern association of electroencephalographers, le chantecler, ste. adele, quebec, canada, march 2--5, 1978. abstracts.		1999	85518
prostatectomy--induced decrease in an enhanced serum testosterone concentration in patients with prostatic hyperplasia and its pathophysiological implications.		1999	85550
[complex genesis of anemia in chronic liver diseases].	36% of a total of chronic liver patients suffered from anaemia and 50.5% of patients affected with liver cirrhosis. in most cases the anaemias were normochrome and hypochrome or hyperchrome only in some cases. in analyzing possible single factors the reductions of vitamin b12 absorption could be made probable by means of the schilling test and sometimes a folic acid deficiency in macrocyte anaemia with normal vitamin b12 absorption by determining the folic acid content in the serum and by succes ...	1999	85589
comparison of counter-current immunoelectrophoresis, latex agglutination, and radioimmunoassay in detection of soluble capsular polysaccharide antigens of haemophilus influenzae type b and neisseria meningitidis of groups a or c.	three serological methods, radioimmunoassay (ria), latex agglutination (lx), and counter-current immunoelectrophoresis (ciep), for sensitivity in the detection of the capsular polysaccharide antigen of haemophilus influenzae type b or neisseria meningitidis groups a and c were compared. ria was consistently the most sensitive, lx the next, and ciep the least sensitive. when ria and lx were used to test cerebrospinal fluid (csf) samples of patients with meningitis, they gave very similar results. ...	1978	85636
effects of phosphodiesterase inhibitors, imidazole and phosphate on cyclic cmp phosphodiesterase are different from those on cyclic amp and cyclic gmp phosphodiesterases.	the effects of various agents on the newly identified cyclic cmp phosphodiesterase (c-pde) in crude extracts of a number of rat tissues and on the enzyme partially purified from the rat liver were examined. papaverine and 1-methyl-3-isobutylxanthine were without effects on c-pde at concentrations that inhibited up to 90% of cyclic amp phosphodiesterase (a-pde) and cyclic gmp phosphodiesterase (g-pde) activities. when assayed using 1 micron substrates, theophylline inhibited c-pde to a lesser ext ...	1978	85641
epidermal cytoplasmic antigens.		1999	85677
in vitro synthesis of infectious transforming dna by the avian sarcoma virus reverse transcriptase.	infectious dna molecules, capable of transforming chicken embryo fibroblasts, can be synthesized by the rous sarcoma virus-associated reverse transcriptase in vitro. the optimal enzymatic conditions employed for infectious dna synthesis also facilitate maximum synthesis of genome length dna. analysis of the dna product synthesized by detergent-disrupted rous sarcoma virus under these conditions indicates that dna complementary to viral rna (minus-strand dna) is genome length in size, whereas dna ...	1979	85719
[interrelationship between the number and metabolic characteristics of lymphocytes and humoral immunity indices during the immunopathological process].		2000	85738
a review of the evidence for methadone maintenance as a treatment for narcotic addiction.		1999	85827
low plasma-25-hydroxyvitamin d without osteomalacia.		1999	85831
excessive sweating and reduction deformities.		1999	85846
visual disability and home lighting.	13 men and 43 women (average age 76) attending a low-vision clinic with visual acuity of 6/18 (snellen) or less had acuity measurements made under standard (measured) hospital conditions, under normal home conditions, and under home conditions with augmented lighting. median levels of ambient lighting in the home were 1/10 of those in hospital, while levels for reading were 1/7. augmented lighting at home (a 60 watt bulb in a small adjustable lamp) improved visual acuity in 82% of subjects, rest ...	1999	85874
units for immunoreactive trypsin.		2000	86024
hypotensive effect of dieting.		2000	86036
treatment of chickenpox pneumonia with adenine arabinoside.		1979	86115
antitumour effect of cimetidine.		2000	86136
[perichordal necroses. contribution to the understanding of the spinal column morphogenesis].	in 12--15 days old rat embryos and 12 days old mouse embryos vitally stained by acridin orange, a perichordal necrosis appears, showing metameric intensifications at the level of the dense sclerotomites. similar aspects were detected in serially sectioned rabbit and human embryos (6--7 mm c.r. length). the authors correlate the necrotic zones mentioned with the inductive functions of the notochord.	1978	86154
specificity and effector-target interaction.	when effector cells were tested on a number of target cells, the most obvious effect observed was a nonselective cytotoxicity that is now known as natural cell-mediated cytotoxicity. the apparent nonselectivity was a result of specific cytotoxic activity against many different antigens on target cells. this specificity was demonstrated in the cross-competition assay in which target cells sharing common antigens selectively inhibited natural cytotoxicity.	2000	86161
[bronchopulmonary tumors. epidemiology].		2000	86174
demonstration of rheumatoid factor idiotypic antigens on peripheral blood b and t lymphocytes from patients with rheumatoid arthritis.	antisera were raised against three polyclonal igm rheumatoid factors (rf). after adequate absorptions, the antisera were rendered idiotype-specific, as assayed by haemagglutination technique. by using the anti-idiotype antisera in indirect immunofluorescence on peripheral blood lymphocytes from the patients used as donors for the immunizing rf, it was demonstrated that 3-14% of the lymphocytes were stained, and thus had membrane-bound structures with idiotypic antigens similar to those of the ci ...	2000	86203
the can serum: demonstrating further polymorphism of m and n blood group antigens.	an antibody defining an antigen that is very similar in structure to m is described. the reactions of this antibody are considered in the light of what is now known of the biochemical structure of the m and n blood group antigens.	2000	86213
[therapeutic indications in hyperthyroidism (author's transl)].	the administration of synthetic antithyroid drugs or of l131, and subtotal resection of the thyroid gland remain the treatments of hyperthyroidism. precise criteria will determine the choice. surgery is the treatment of large goitres, of associated ophthalmic disorders and of recurrence after medical treatment. drugs are indicated at the first occurrence of hyperthyroidism in young subjects with a small goitre; it will also be used as a preparation for surgery associated to lugol and levothyroxi ...	2000	86256
counterimmunoelectrophoresis of blood cultures. temporal relationship of positive gram stain to positive counterimmunoelectrophoresis.	counterimmunoelectrophoresis (cie), gram staining, and quantitative measurements were performed on simulated blood cultures at hourly intervals after inoculation with streptococcus pneumoniae, klebsiella pneumoniae, or haemophilus influenzae. the cie became positive either at the same time as the gram stain or within the ensuing five hours. in no case was cie positive when the gram stain was negative. the numbers of colony-forming units milliliter necessary for a positive cie result varied with ...	1979	86293
counterimmunoelectrophoresis for rapid identification of blood-culture isolates.	a total of 303 blood cultures that were positive by examination of gram-stained smears were tested immediately by counterimmunoelectrophoresis for detection of bacterial antigens. antigen was detected in all 82 blood cultures containing streptococcus pneumoniae and 11 of 22 with klebsiella pneumoniae, two of two with haemophilus influenzae, and one of one with neisseria meningiditis. false-positive cross-reactions in 265 tests occurred only with pneumococcal omniserum in two cases of nongroupabl ...	1979	86294
immunochemical, serologic, and immunologic properties of major antigens isolated from the legionnaires' disease bacterium. observations bearing on the feasibility of a vaccine.	two antigens were isolated from each of three strains of the legionnaires' disease (ld) bacterium. one antigen was serotype-specific; the other cross-reacted with strains of ld bacteria of different serotypes. the serotypic antigens contained all the major branched-chain fatty acids characteristic of ld bacteria and were a lipid-protein-carbohydrate complex. electrophoresis resolved the serotypic antigen of knoxville 1 strain into four protein bands and one glycoprotein band with molecular weigh ...	1979	86314
the isolated human cortex. a golgi analysis of krabbe's disease.	the clinical course of a child with krabbe's leukodystrophy was characterized by clinical seizures, startle myoclonus, and paroxysmal activity recorded by eeg. at autopsy in the fourth year, myelinated subcortical axons were destroyed, virtually completely. despite isolation from major subcortical and interhemispheric connections, the cell and fiber pattern of the cortex appeared remarkably normal in routine histologic preparations. the normal range of pyramidal and stellate interneurons were al ...	1979	86346
difference in antigenic reactivity and ultrastructure between fluid-phase c5b-9 and the c5b-9 membrane attack complex of human complement.		1979	86461
ultrastructure of peptidergic neurosecretory axons in the developing neural lobe of the rat.		1978	86479
[evaluation of air pollutants analysis for the benefit of environmental technology].		2000	86480
purification and characterization of a polyhook protein from caulobacter crescentus.	a polyhook-producing strain of caulobacter crescentus was isolated, and the polyhook protein was purified. the antigenicity and morphology of the polyhook structure are similar to the wild-type hook except that the mutant strain produces a hook structure at least 10-fold the length of wild-type hooks (1.0 versus 0.1 micrometers). the molecular weight of the polyhook protein, as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, is 72,000, and the protein has a pi of approxi ...	1979	86537
identification of polymorphonuclear leukocytes in cytologic samples for flow cytometry.	inflammatory cells are commonly present in cytologic specimens obtained for flow cytometry, and may interfere with the analysis of epithelial cells. we have found that detergent (triton x-100) pretreatment in the two-step acridine orange staining procedure disrupts granulocyte cell membranes to yield bare nuclei; bladder epithelial and squamous cells on the other hand are quite resistant to the detergent treatment. being deprived of their cytoplasmic rna, the granulocytes lose red fluorescence. ...	2000	86568
automatic cell identification and enrichment in lung cancer. iii. light scatter and two fluorescence parameters.	two fluorescence parameters and size are used in a flow through system to enrich sputum specimens for cancer cells. human cells in sputum which are stained with acridine orange show a characteristic distribution of red and green fluorescence from which cancer cells can be localized. the peak enrichment is obtained by selectively sorting cells with the largest values of red and green fluorescence. cancer cells located in other distribution regions having smaller fluorescence intensities show prog ...	1979	86577
cytofluorometric and cytochemical comparisons of normal and abnormal human cells from the female genital tract.	acridine orange staining of exfoliated cells from epithelial tissues facilitates discrimination between normal and abnormal cells: abnormal cells develop highly elevated nuclear fluorescence. comparisons of acridine orange (ao) staining with propidium iodide (pi) or feulgen staining have shown that: (a) pi staining also provides highly elevated nuclear fluorescence from abnormal cells; (b) the distributions of nuclear fluorescence following ao or pi staining were usually not significantly differ ...	1979	86579
acriflavine-feulgen stilbene staining: a procedure for automated cervical cytology with a television based system (leytas).	a sample preparation and staining procedure for automated cytology with a tv based system (leytas) is described. it consists of a centrifugation technique and automated acriflavine-feulgen stilbene staining of cervical specimens. the advantages of using both the fluorescence and the absorption image of acriflavine-feulgen stilbene stained cervical cells for a television based system are discussed.	2000	86584
the results of prostatectomy: a symptomatic and urodynamic analysis of 152 patients.	there were 152 patients with prostatism investigated by inflow cystometry and pressure flow analysis of micturition before and after elective prostatectomy. many symptoms attributed to obstruction were found to be owing to bladder instability, which was demonstrated in 60 per cent of the patients. the symptomatic improvement postoperatively was accompanied by a decrease in the incidence of instability to 25 per cent. the repeat urodynamic studies and symptom analysis demonstrated a surgical succ ...	2000	86617
[gelatin as a stabilizer in hemagglutination and hemagglutination inhibition reactions with arboviruses].		2000	86655
does photochemotherapy increase the risk of skin cancer?		2000	86724
research into lead pollution.		2000	86732
neutrophil cytochrome b in chronic granulomatous disease.		2000	86758
radiation doses after three mile island.		2000	86763
beta blockers for glaucoma.		2000	86781
hla typing of amniotic-fluid cells applied to prenatal diagnosis of congenital adrenal hyperplasia.		2000	86789
examination of immigrants.		2000	86808
sepsis, septicaemia, and the sea.		1979	86842
heatstroke.		2000	86848
detection of small numbers of monoclonal b lymphocytes in the blood of patients with lymphoma.	the definition of complete remission and early relapse in patients with lymphoid malignancy is complicated by the difficulty of recognizing the presence of small numbers of malignant lymphocytes in a population of normal lymphocytes. we have used a method based on the cytofluorometric detection of lymphocytes having homogeneous amounts of surface immunoglobulin of one light-chain class to study blood from patients with lymphomas. the test is capable of reliably detecting 10 per cent or less of m ...	2000	86953
[follow-up study of glioblastoma--a review of 179 cases (author's transl)].		2000	86960
isolation and characterization of an endogenous type c virus of rhesus monkeys.	a type c retrovirus was isolated from a continuous cell line established from a spontaneous esophageal carcinoma of a rhesus monkey (macaca mulata) by prolonged cocultivation with canine cells. a dna transcript of the viral rna hybridized to a high level and kinetic analysis indicated the presence of multiple copies of the viral genome in rhesus monkey dna, showing that the virus is endogenous in this species. the rhesus monkey virus closely resembles, in several respects, an endogenous type c v ...	1979	87013
hla histocompatibility antigens in a polynesian population -- cook islanders of mauke.	polynesians living on the island of mauke in the cook island group were typed for hla-a and -b locus antigens. the mauke population has restricted hla polymorphism, with five a-locus antigens and four b-locus antigens accounting for a majority of the hla phenotypes. although some differences in antigen frequency were found when mauke islanders were compared with polynesians from easter island and samoa, the mauke islanders were closer in their hla antigenic profile to polynesians than to melanes ...	2000	87022
a new hla--c specificity (t9) in linkage disequilibrium with hla--b14.		2000	87025
leucocyte migration inhibition test as an index of immunological response to measles virus. iv. blood, spleen, lymph nodes and peritoneal exudate cell reaction.	the migration inhibition test of leucocytes isolated both from the peripheral blood, spleen and lymph nodes as well as peritoneal exudate cells of guinea pigs, immunized with the various doses of measles virus was determined. for in vitro testing of cellular immunity to measles virus, viral antigens could be used in both infective and inactivated form.	1979	87118
tricyclic antidepressants and prostatic enlargement. preliminary report.		2000	87135
bleomycin.	bleomycin was approved by the food and drug administration in 1975 for therapy against squamous cell carcinomas, testicular cancers, and malignant lymphomas. an extensive bibliography on this drug indicates that there is little evidence of activity against other malignancies. although initially used exclusively as a single agent, bleomycin has been considered recently for use in combination chemotherapy. because of associated toxicity involving the lung and mucous membranes, bleomycin should be ...	2000	87142
similarity of casein- and endotoxin-induced, myeloma- associated and aged sjl/j amyloid in various strains of mice.	amyloidosis was induced in a number of strains of mice by repeated injections of casein and endotoxin. spontaneous amyloid was obtained from balb/c mice bearing a myeloma tumor (igg2a producing mopc 173 tumor) and from aged sjl/j mice. both the induced and spontaneous forms were similar in their size, immunological reactivity, peptide maps and in the susceptibility of histological sections to oxidizing agents with or without trypsin digestion. since case-induced murine amyloid resembles the noni ...	1979	87374
mode of action of a 5-nitrofuran drug (sq 18506) against trypanosoma cruzi.		1979	87384
intracellular marking with lucifer yellow ch and horseradish peroxidase of cells electrophysiologically characterized as glia in the cerebral cortex of the cat.	intracellular microelectrodes filled with either lucifer yellow ch, a highly florescent dye, or horseradish peroxidase (hrp) were used to electrophysiologically characterize and mark cells in the cerebral cortex of cat. fifty-eight cells, characterized electrophysiologically as glia, were marked with lucifer yellow ch. all were identified as protoplasmic astrocytes, and included cells in the glia limitans of the molecular layer. an additional 54 cells, similarly characterized as glia, were label ...	1979	87405
specific binding of t lymphocytes to macrophages. v. the role of ia antigens on mphi in the binding.	the effect of anti-ia alloantiserum on the capacity of selected peritoneal exudate lymphocytes (selected pel) to bind to antigen-pulsed f1 (responder x nonresponder) macrophages was investigated. with the use of selected pel for antigens under ir gene control, it was shown that anti-ia serum to the responder haplotype blocked adherence of selected pel to antigen-pulsed macrophages whereas anti-ia serum to the nonresponder haplotype did not. the target cell of the anti-ia alloantiserum appeared t ...	1979	87437
inhibition of antibody production in plasmacytoma cells. iii. interactions of suppressive and nonsuppressive dnp conjugates with mopc 315 cells.		2000	87442
evidence for shared idiotypy expressed by the igm, igg, and iga serum proteins of a patient with a complex multiple paraprotein disorder.	the results of a comparative idiotypic analysis of multiple ig paraproteins isolated from the serum of an individual patient, ca, with sjögren's syndrome and waldenström's macroglobulinemia are reported. at initial presentation, ca serum was found to contain two major paraproteins, an igmkappa and an iggkappa, together with a small elevation in the level of iga protein. the patient's clinical course was characterized by dramatic and opposing changes in the respective serum levels of the igmkappa ...	2000	87449
immunoregulation of murine myeloma: isologous immunization with m315 induces idiotype-specific t cells that suppress iga secretion by mopc-315 cells in vivo.		2000	87450
in vitro analysis of allogeneic lymphocyte interaction. iv. dual recognition of b cell-associated mls locus and i-region determinants by a helper allogeneic effect factor (aef) generated across a minor h locus disparity.	a helper allogeneic effect factor (aef) was produced across an incompatibility at the minor histocompatibility loci. this aef is genetically restricted in its activity since it helps b cells only of the stimulator haplotype and of haplotypes that share both an mls and i-region identity with the stimulator haplotype. the i-region genes involved here map to the i-a and/or i-c subregions. an anti-lym immunoadsorbent column but neither an anti-h-2 nor an anti-ia column absorbed aef helper activity. ...	2000	87470
uptake of iron by duodenal biopsy specimens from patients with iron-deficiency anaemia and primary haemochromatosis.	iron uptake by human duodenal mucosa in vitro was considerably higher in iron-deficient patients than in controls. in biopsy specimens taken after treatment with iron, uptake fell to normal levels, although total iron in the mucosa remained low. in iron-overloaded patients with primary haemochromatosis, there was inappropriately high uptake of iron by the biopsy specimens. kinetic analysis suggested that this was the result of affinity for iron being increased in a carrier in the enterocyte.	1978	87554
pneumococcal vaccines.		1978	87558
taking a history from the difficult patient.		2000	87566
glutamic-acid decarboxylase in schizophrenia.		2000	87592
homocystinuria and oral contraceptives.		2000	87596
diagnosing thyroid nodules.		2000	87601
combination chemotherapy with cis-diammine-dichloro-platinum, vinblastine, and bleomycin in advanced testicular non-seminoma.	40 patients with disseminated testicular non-seminoma were treated with cis-diammine-dichloro-platinum, vinblastine, and bleomycin. complete remission was achieved in 24 (60%) patients and partial remission in 11 (28%). 22 of the 24 complete responders, who have been followed-up for a median of 11 months, have been tumour-free for 5--30 months. there were 3 drug-related deaths. this regimen is the most effective remission-induction treatment available for disseminated testicular non-seminoma. pa ...	2000	87614
cure of aplastic anaemia in paroxysmal nocturnal haemoglobinuria by marrow transfusion from identical twin: failure of peripheral-leucocyte transfusion to correct marrow aplasia.	the ability of syngeneic peripheral leucocytes to cure marrow aplasia was tested in a patient with paroxysmal nocturnal haemoglobinuria (p.n.h.). transfusion of 7.1x10(10) white cells obtained by leucopheresis from an identical-twin donor, providing 3.4x10(4) myeloid progenitors (c.f.u.-c)/kg, failed to improve marrow function within two months. in contrast, transfusion of 1.3x10(10) nucleated bone-marrow cells, representing 6.4x10(4) c.f.u.-c/kg, from the same donor resulted in prompt bone-marr ...	2000	87615
postpartum fluid retention.		2000	87622
diagnosis of tay-sachs disease on blood obtained at fetoscopy.		2000	87633
two-week postnatal examination of infants.		2000	87641
lipid profiles in dioxin-exposed workers.		2000	87655
cytoplasmic copper and its toxic effects. studies in indian childhood cirrhosis.	morphological, histochemical, and chemical study of three necropsy specimens of liver in the terminal stage of indian childhood cirrhosis revealed a strikingly high copper content. it is proposed that excess accumulation of copper in the cytoplasm of hepatocytes disturbs the microtubular system, causing hydropic swelling and the formation of mallory's hyalin. copper and copper-binding protein showed topographical association with mallory's hyalin. diffuse cytoplasmic staining and the lysosomal c ...	2001	87676
surgical wound sepsis.		2001	87737
selective damage to cholinergic nerves: possible cause of postoperative ileus.		2001	87738
extent of cuts in computerised tomography of the brain.		2001	87763
leucocyte-counts and survival in lung cancer.		2001	87807
ampicillin-insensitive haemophilus influenzae type b causing acute epiglottitis.		1979	87819
alan trevor jones.		2001	87827
tuberculosis chemotherapy--how long.		1979	87838
the rubella immunity gap.		2001	87852
new consultant contract.		2001	87861
allergy to alpha-amylase and papain.		2001	87867
optimised blood-pressure.		2001	87901
sex ratio in glomerulonephritis.		2001	87939
george armitage.		2001	87943
synaptic hyperfunction in sympathetic ganglion, its significance in essential hypertension.		1979	87949
minaxolone: a new water-soluble steroid anaesthetic.	the induction characteristics of minaxolone, a water-soluble steroid anaesthetic, were studied in fit patients undergoing minor urological or gynaecological operations. minaxolone acted as rapidly as thiopentone. a dose of 0.25 mg kg-1 did not always produce anaesthesia in patients who had not received premedication but 0.5 mg kg-1 was an adequate dose. excitatory effects were less common with the higher doses of anaesthetic. these effects were usually slight and rarely interfered with the cours ...	2001	87969
[surgical treatment of congenital obstructive biliary disease (author's transl)].	the results of surgical treatment of bile duct atresia and hypoplasia are disappointing; no improval of long-term survival could be observed. with kasai's hepato-jejuno-enterostomy which is not suited for the management of complete atresia. a new surgical procedure was evaluated in animal experimentation and in some patients: the bile was drained through the lymph system of the liver into the intestinal tract. morphology, surgical procedure and indications as pertinent to this new approach are d ...	1979	87998
providing continuing education in a nephrology program--part ii.		2001	88021