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13c nmr studies of carboxylate inhibitor binding to cobalt(ii) carboxypeptidase a.both 13c nmr and electronic absorption spectral studies on cobalt(ii) carboxypeptidase a in the presence of acetate and phenylacetate provide evidence for two binding sites for each of these agents. the transverse relaxation rate t2-1 for the 13c-enriched carboxyl groups of the inhibitors is significantly increased when bound to the paramagnetic cobalt carboxypeptidase as compared to the diamagnetic zinc enzyme. the acetate concentration dependence of t2p-1 shows two inflections indicative of se ...20123346659
transient heart block associated with head trauma.atrioventricular nodal block is a rare consequence of head trauma. we report a case of a 63-year-old male with coronary artery disease who sustained a skull fracture. twelve hours later the cardiac monitor recorded an episode of high-grade atrioventricular block with a ventricular escape rhythm. subsequent electrophysiologic evaluation revealed no abnormality of atrioventricular nodal conduction nor of intraventricular conduction. atrioventricular block after head trauma may be caused by enhance ...20113346929
transient heart block associated with head trauma.atrioventricular nodal block is a rare consequence of head trauma. we report a case of a 63-year-old male with coronary artery disease who sustained a skull fracture. twelve hours later the cardiac monitor recorded an episode of high-grade atrioventricular block with a ventricular escape rhythm. subsequent electrophysiologic evaluation revealed no abnormality of atrioventricular nodal conduction nor of intraventricular conduction. atrioventricular block after head trauma may be caused by enhance ...20113346929
[meningoencephalitis and mononucleosis syndrome associated with acute infection by human immunodeficiency virus]. 19883347109
the unborn patient. 19883347563
extensor tendon involvement in smith's and faleazzi's fractures. 20123351262
diagnosis of right ventricular involvement in chronic inferior myocardial infarction by means of body surface qrs changes.st segment elevation in right precordial leads is thought to be good predictor of right ventricular involvement in patients with acute inferior myocardial infarction. this view, however, is rapidly disappearing. therefore, using qrs changes in body surface potential maps in the chronic phase, we have attempted to differentiate patients with or without right ventricular involvement. thirty patients with chronic inferior myocardial infarction (2 or more months after onset) were studied, in whom 87 ...20123370768
lactational response to soybean meal, heated soybean meal, and extruded soybeans with ruminally protected methionine.seventy-three high producing holstein cows were arranged in a 3 x 2 factorial to evaluate three protein supplements (soybean meal, heat-treated soybean meal, and extruded blend of soybeans and soybean meal) without or with 15 g/head/d of ruminally protected dl-methionine during wk 4 through 16 postpartum. total mixed diets contained (dm basis) 30% corn silage, 15% alfalfa hay, and 55% of the respective concentrate mix. milk production was higher when cows were fed either heated soybean product i ...19883372801
skull development during anuran metamorphosis: i. early development of the first three bones to form--the exoccipital, the parasphenoid, and the frontoparietal.in anuran amphibians, cranial bones typically first form at metamorphosis when they rapidly invest or replace the cartilaginous larval skull. we describe early development of the first three bones to form in the oriental fire-bellied toad, bombina orientalis--the parasphenoid, the frontoparietal, and the exoccipital--based on examination of serial sections. each of these bones is fully differentiated by gosner stage 31 (hindlimb in paddle stage) during premetamorphosis. this is at least six gosn ...20123379643
insights on death & dying. depression: bottled-up emotions. 20123386914
anesthesia-related maternal mortality in michigan, 1972 to 1984.we reviewed maternal deaths in the state of michigan occurring from 1972 through 1984. there were 15 maternal deaths in which anesthesia was considered the primary cause and 4 deaths in which anesthesia was a contributory factor. complications of regional anesthesia were the main cause of death during the early part of the period, whereas the inability to accomplish endotracheal intubation emerged as the principal cause of death in recent years. eleven of the 15 patients had undergone cesarean s ...20123394738
[the differentiation of bordetella bronchiseptica strains. 7. phenotypic changes in bordetella bronchiseptica through changes of phase]. 19883395180
an outbreak of cholera in a refugee camp in africa.a total of 541 cases of cholera were observed between may 7 and july 19, 1985 among the 9,929 displaced persons present in a refugee camp in africa. in spite of malnutrition and other diseases affecting this population, only 12 deaths occurred. antiepidemic measures consisted of preparation of isolation-wards, treatment of contaminated materials, training of refugees and patient care. mass prophylaxis, initially considered, was dropped before the end of the epidemic.20123402580
doctors using lasers risk problems without proper training, protection. 20123405576
experimental evaluation of the mitroflow pericardial heart valve prosthesis. part i. in vivo hemodynamic evaluation.evaluation of possible enhanced durability of the mitroflow pericardial heart valve prosthesis was undertaken in an experimental animal model using the chacma baboon. for comparison purposes a small series of 4 ionescu-shiley pericardial valves were also implanted. the 33 mitroflow prostheses implanted were all manufacturer's size 21mm and belonged to 4 different groups according to the process used for the preparation of the pericardium (process i to iv). the ionescu-shiley prostheses were all ...20123421506
experimental evaluation of the mitroflow pericardial heart valve prosthesis. part ii. pathologic examination.the results of the morphologic and histopathologic examination of 37 bovine pericardial heart valve prostheses that were retrieved after experimental implantation in chacma baboons for periods of one to twelve months are presented in this study. the implanted prostheses consisted of 33 mitroflow valves, size 21 mm, that belonged to four different groups according to the method of preparation of the pericardium (process i to iv) and 4 commercially available ionescu-shiley valves, size 19 mm. all ...19883421507
ureterocolonic anastomosis in clinically normal dogs.ureterocolonic anastomosis was evaluated in 13 clinically normal dogs. urinary continence was maintained after surgery, and the procedure was completed without technique errors in all but 2 dogs. three dogs died within 5 weeks (2 of undetermined causes and 1 of aspiration pneumonia and neurologic disease), and 1 dog was euthanatized 4 months after surgery because of neurologic signs. two healthy dogs were euthanatized 3 months after surgery for light microscopic evaluation of their kidneys. five ...19883421537
facilitatory action of adrenergic drugs on muscle twitch evoked by nerve stimulation in the curarized rat phrenic hemidiaphragm.the facilitatory effects of alpha-adrenergic drugs on neuromuscular transmission has been studied in the curarized rat phrenic-hemidiaphragm. the reversal effect of blocking action of (+)-tubocurarine on indirectly-induced twitch by alpha-adrenergic agents was higher with noradrenaline (ec50 = 6.51 +/- 0.18 microm) compared with adrenaline (ec50 = 11.80 +/- 1.06 microm) or phenylephrine (ec50 = 17.36 +/- 1.02 microm). methoxamine, clonidine and azepexol showed no effect. the action of noradrenal ...19883421779
cardiac effects of botulinal toxin.crystalline type a botulinal toxin rapidly caused temporary bradycardia and electrocardiographic (ecg) changes in mice, rats, rabbits and dogs. in addition, in the dog the force of contraction was measured and found to be depressed. the ecg changes were indicative of conduction defects. the hemagglutinin present in the toxin played no role in the effects on the heart, since a derivative toxin without hemagglutinin also caused these phenomena. the cardiac effects were spontaneously reversible in ...19883421785
[indirect cervical trauma: long-term adverse prognostic factors]. 20123423548
[various problems of immunological prevention: changes in the schedule of preventive vaccination]. 20123432015
heterologous protection in murine cutaneous leishmaniasis.mice immunized with a glycolipid antigen (gl) of leishmania major plus adjuvant are relatively resistant to subsequent infection with this protozoan parasite. the gl is affinity purified on the monoclonal antibody wic-79.3 which is l. major-specific and does not react with l. donovani. when another monoclonal, wic-108.3, which cross-reacts with several leishmania species, is used to affinity purify gl from l. donovani, the eluted material can partially protect genetically resistant mice against ...19873436638
[late results of organ-sparing surgical treatment of patients with balkan endemic nephropathy and tumors of the upper urinary tract]. 20123437707
[the postcholecystectomy syndrome]. 20123454415
alternative protein products with different carboxyl termini from a single class i gene, h-2kb.in addition to mrna encoding the canonical form of the murine class i antigen h-2kb (348 amino acid residues), mrna that would encode a shortened form of h-2kb (missing 9 amino acids from the c-terminus) has been identified in c57bl/6 spleen cells by rnase-protection studies. the alternative transcripts of h-2kb arise through the use of different ag acceptor splice sites for exon viii. the existence of a shortened h-2kb protein was demonstrated by sequential immunoprecipitation. lysates of splee ...19863461476
[indications and prognosis of the iso titanium cone system]. 20123471501
[nationwide study of the antimicrobial susceptibility of clinical isolates of proteus group in japan].we discussed the antimicrobial susceptibilities of proteus group isolated in 1983 and 1984 and also the annual changes of the susceptibilities from 1980 to 1984. the tested strains were isolated in 103 hospitals in japan. antibiotics tested for this study were ampicillin (abpc), cefazolin (cez), cefmetazole (cmz), and gentamicin (gm). the mic's were determined by the standard method of the japan society of chemotherapy. susceptibilities of the bacterial strains to the 4 antibiotics were describe ...19873475483
[contact lenses for the correction of ametropia: indications, adaptation, complications of wearing lenses]. 20123475745
in vitro study of the antibacterial activity of ofloxacin against recent clinical isolates.the in vitro activity of ofloxacin, a new broad-spectrum antimicrobial agent, was studied by a standardized single disc method. a total of 990 clinical isolates were tested, including 20 strains of anaerobic bacteria. ofloxacin was highly active against 683 strains (70.41%), had intermediate activity against 109 (11.23%) and had no activity against 178 (18.35%). ofloxacin was highly active against e. coli, klebsiella sp., citrobacter sp., proteus mirabilis, proteus morganii, salmonella sp., camp ...19873476290
abnormal monocyte function in patients with kaposi's sarcoma.monocyte-mediated functions were evaluated in the peripheral blood mononuclear cells (pbmc) of 11 previously untreated patients with kaposi's sarcoma in association with the acquired immune deficiency syndrome (ks/aids). all patients had lymphadenopathy, an abnormal okt.4/okt.8 ratio, and a good performance status; none had clinically apparent infections at the time of testing. monocyte functional assessments included immunoregulatory activity in phytohemagglutinin-stimulated (pha) lymphoblastog ...20123485009
changes in caloric nystagmus induced by vasodilating drugs.systemic blood flow, blood flow to the peripheral skin, middle ear, and temporal bone, and that to the inner ear of normal volunteers was manipulated selectively through the use of vasodilator drugs. the effect of selective vasodilation was monitored via changes in the temporal course of the slow-phase velocity of nystagmus evoked by bithermal caloric irrigation. drug influenced eye velocities were compared with control values measured before drug administration. eye velocities measured after ni ...20123485753
haemophilus influenzae type b colonization in household contacts of infected and colonized children enrolled in day care.strategies for management of children attending day-care facilities after a case of haemophilus influenzae type b disease are controversial. the success of chemoprophylaxis in preventing subsequent cases has been variable. failure of rifampin prophylaxis as currently recommended may result from usage limited to direct contacts of the index patient. this prospective study was designed to ascertain the extent of colonization in household contacts of colonized children attending day-care facilities ...19863487771
tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.tumor necrosis factor type alpha (tnf-alpha) is produced by monocytes and has been purified, sequenced, and cloned from the hl-60 cell line. soluble products of monocytes stimulate endothelial cells to release multilineage hematopoietic colony-stimulating activity. to determine whether tnf-alpha could stimulate endothelial cells to produce these activities, we added recombinant human tnf-alpha to cultured human umbilical vein endothelial cells. untreated endothelial cell conditioned medium and t ...19863489939
in vitro activity and beta-lactamase stability of a new penem, cgp 31608.the in vitro activity of cgp 31608, a new penem, against aerobic and anaerobic organisms was evaluated and compared with those of other beta-lactams. cgp 31608 inhibited escherichia coli, klebsiella pneumoniae, k. oxytoca, proteus mirabilis, citrobacter diversus, and salmonella, shigella, aeromonas, and yersinia spp. with mics for 50% of the strains (mic50s) of 2 to 4 micrograms/ml and mic90s of 4 micrograms/ml, compared with cefotaxime, ceftazidime, aztreonam, and imipenem mics of less than 0.2 ...19873496845
comparative activity of ceftizoxime against aminoglycoside-resistant aerobic gram-negative bacilli.the in vitro activity of ceftizoxime was compared with that of other beta-lactam antibiotics against 331 aminoglycoside (ag)-resistant clinical isolates. two hundred and six ag-resistant, beta-lactamase producing, r-plasmid harbouring enterobacteriaceae strains had mics ranging from 0.0125 to 0.063 mg/l. ag-resistant escherichia coli (36 strains) and klebsiella pneumoniae (19) had mic 90 values of 8 mg/l. proteus rettgeri and p. vulgaris as well as morganella morganii, resistant to several ags, ...19873497792
[age-related changes in lectin binding patterns of rat cartilaginous tissues]. 19873505808
[age-related changes in lectin binding patterns of rat cartilaginous tissues]. 19873505808
the influence of miotics on the visual field. 20123507913
the role of blood transfusion in the age of cyclosporine. 20133515691
the role of blood transfusion in the age of cyclosporine. 20133515691
lipopolysaccharide of providencia rettgeri. chemical studies and taxonomical implications.the chemical constitutional analysis of the lipopolysaccharide (lps) isolated from providencia rettgeri was carried out. polyacrylamide gel electrophoresis using sodium dodecylsulfate or sodium deoxycholate showed that the lipopolysaccharide mostly consisted of short sugar chains. the lipid a was precipitated out after mild acid hydrolysis of lps. from the supernatant degraded polysaccharide and unsubstituted core fractions were isolated. compositional analysis of the core material revealed the ...19863524498
[pit and fissure sealants. the effect of etching depends on the differences in tooth surface cleaning methods, and the method of cleaning pits and fissures]. 20123526496
ferric ammonium citrate decomposition--a taxonomic tool for gram-negative bacteria.the iron uptake test of szabó and vandra has been modified and used for the differentiation of gram-negative bacteria. nutrient agar containing 20 g per litre of ferric ammonium citrate was distributed into narrow tubes and solidified so as to form butts and slants. considering the localization of the rusty-brown coloration produced after seeding and incubation, 2367 strains were classified into four groups. (1) unchanged medium: escherichia coli, shigella spp., yersinia spp., hafnia alvei and m ...19863529797
expression and regulation of the penicillin g acylase gene from proteus rettgeri cloned in escherichia coli.the penicillin g acylase genes from the proteus rettgeri wild type and from a hyperproducing mutant which is resistant to succinate repression were cloned in escherichia coli k-12. expression of both wild-type and mutant p. rettgeri acylase genes in e. coli k-12 was independent of orientation in the cloning vehicle and apparently resulted from recognition in e. coli of the p. rettgeri promoter sequences. the p. rettgeri acylase was secreted into the e. coli periplasmic space and was composed of ...19863531181
[focal and diffuse nesidioblastosis and persistent neonatal hyperinsulinemic hypoglycemia. a morphologic analysis of 12 patients]. 20123534873
magnesium-dependent plaque formation by bacteriophage p1cinc(-) on escherichia coli c and shigella sonnei.phage p1c(-), in a state of the phage not infective to escherichia coli k12, was able to form plaques on a wild-type strain of e. coli c and on shigella sonnei in the presence of mg2+. citrobacter freundii, enterobacter aerogenes, and a salmonella typhimurium gale mutant were not lysed by, but were lysogenized with p1cinc(-), whereas klebsiella pneumoniae, proteus rettgeri, and s. typhimurium lt2 were not susceptible to either p1cinc(-) or p1cinc(+). the lipopolysaccharide structure of e. coli c ...19863535235
analysis of thyroglobulin antibody synthesis by cultured peripheral blood lymphocytes from patients with hashimoto's thyroiditis using biotin-avidin solid phase enzyme immuno-assay.the influence of bovine thyroglobulin (tg) and/or staphylococcus aureus cowan i (sac) on tg antibody synthesis has been studied using cultures of 8 hashimoto's and 5 normal peripheral blood lymphocytes (pbl). the detection of tg antibody in the culture supernatants was performed by sensitive biotin-avidin solid phase enzyme immunoassay. by using this technique, we were able to detect small amounts of tg antibody synthesized by cultured hashimoto's pbl responsive to bovine tg and/or sac; pbl from ...19863539581
electrophoretic mobility, concentration, and activity of alpha 1-antitrypsin in serum of patients undergoing bone-marrow transplantation.we have observed an electrophoretically abnormal, nonfunctional species of alpha 1-antitrypsin in serum from patients who were receiving bone-marrow transplants for treatment of leukemia or aplastic anemia. three of four patients in whose serum this protein appeared died soon after; the fourth recovered, and the disappearance of the abnormal alpha 1-antitrypsin paralleled his recovery. this suggests that the inability to maintain functional activity of alpha 1-antitrypsin predisposes patients to ...20123542290
[mutants of escherichia coli k-12 with increased resistance to ionizing radiation. vi. increased radioresistance and heat shock proteins].by means of one-dimensional electrophoresis, it is shown that in radiation-resistant gamr444 and gamr445 mutants of escherichia coli k-12 high-molecular weight heat shock proteins are hyperproduced at 32-37 degrees c and are induced more intensively during heat shock (in comparison to the parental wild-type strain ab1157). when the missense htpr15 mutation of the positive regulatory htpr gene for heat shock proteins was introduced by transduction into the genome of the gamr444 mutant, its enhanc ...19863542709
[the effect of subinhibitory concentrations of cefaclor, erythromycin and doxycycline on phagocytosis and intracellular killing of e. coli by human neutrophil granulocytes].after determination of granulocyte basic parameters of polymorphonuclear neutrophilic leukocytes obtained from 5 unselected intensive care unit patients and 5 healthy volunteers phagocytosis of an e. coli strain isolated from clinically proven infection (urinary tract infection) was investigated with and without preincubation of the strain with subinhibitory concentrations (1/4 and 1/2 minimum inhibitory concentration; incubation time: 30 min) of cefaclor, erythromycin and doxycycline. the resul ...19863545226
the morphology and distribution of serotonin-like immunoreactive fibers in the cat dorsal column nuclei.fibers showing serotonin-like immunoreactivity (5-ht-li) are demonstrated in the gracile, cuneate and external cuneate nuclei of the cat using avidin-biotinylated horseradish peroxidase and indirect fluorescence immunohistochemical methods. 5-ht-li fibers are located in all cytoarchitectural subdivisions of the gracile and cuneate nuclei but are restricted to the medial half of the external cuneate nucleus. in all nuclei, 5-ht-li fibers consist of long, varicose strands showing a wide range in t ...19873554006
synergy of fosfomycin with beta-lactam antibiotics against staphylococci and aerobic gram-negative bacilli.fosfomycin inhibits bacterial cell wall synthesis at the initial stage. it can act synergistically with beta-lactams. the effect of the combination of fosfomycin and selected penicillins and cephalosporins against staphylococci, pseudomonas aeruginosa, pseudomonas cepacia and selected gram-negative bacteria was determined. synergy was determined by agar dilution and checkerboard titration methods; synergy was defined as an fic index less than or equal to 0.5 and partial synergy greater than 0.5 ...19863569007
granular cell myoblastoma (gcm): contribution of three cases with genital involvement.granular cell myoblastoma (mgc) is an uncommon benign tumor of mesodermal origin of which no more than sixty cases with genital involvement have been reported. among the genital organs, the labium majus of the vulva are the predilect site. we hereby contribute three new cases with a genital location (two in the vulva and one in the breast) and review the literature on the subject.20133569328
effects of peptide yy on gallbladder motility.the effects of peptide yy (pyy) on cholecystokinin-stimulated gallbladder contraction were investigated in the prairie dog model. twelve animals underwent laparotomy with catheter placement into the gallbladder and common bile duct (vent). the gallbladder was continuously perfused with [14c]polyethylene glycol-labeled lactated ringer at 0.03 ml/min, and vent effluent was collected at 2.5-min intervals. all animals received 20 min of intravenous infusion of cholecystokinin octapeptide (cck-op), 2 ...19873591942
differentiation of isotopically labeled nucleotides using fast atom bombardment tandem mass spectrometry. 20133592217
alcohol and the brain: neuropsychological correlates. 20133597943
[evaluation of tricuspid regurgitation before and after open heart surgery by pulsed doppler echocardiography--assessment of indications for tricuspid surgery]. 20133598260
[the biochemistry of toxic effects]. 20133623325
genetic and biochemical diversity of ureases of proteus, providencia, and morganella species isolated from urinary tract infection.bacterial urease, particularly from proteus mirabilis, has been implicated as a contributing factor in the formation of urinary and kidney stones, obstruction of urinary catheters, and pyelonephritis. weekly urine specimens (n = 1,135) from 32 patients, residing at two chronic-care facilities, with urinary catheters in place for greater than or equal to 30 days yielded 5,088 phenotypically and serotypically diverse bacterial isolates at greater than or equal to 10(5) cfu/ml. a total of 86% of sp ...19873623698
painful piezogenic pedal papules in patients with ehlers-danlos syndrome.painful piezogenic pedal papules were observed in 10 of 29 patients with ehlers-danlos syndrome. the diagnosis was made by examining each patient while he or she stood with full body weight on the heels and by observing the appearance of the painful papules on the medial, posterior, and lateral aspects of both heels. biopsy specimens of papules demonstrated a thickened and dense dermis. the subcutaneous fibrous trabeculae were thin, with resultant poor compartmentalization of the fat. painful pi ...20133624559
[high mortality of the nile tilapia oreochromis niloticus caused by providencia rettgeri]. 19873632601
integrating political education into nursing curriculum. 20133647896
women's health: where do we go from here? 20133647905
drugs & geriatric surgery. implications for pre-operative and post-operative care. 20133647926
[rehabilitation and interprofessional communication: the nurse, pt (physical therapist), ot (occupational therapist), and st (speech therapist)]. 20133656730
effect of type of anesthesia on blood loss at cesarean section. 20133658294
effect of flutamide, a nonsteroidal antiandrogen on testis and accessory genital organs of male rats: a reevaluation in prepubertal and adult rat. 19873666808
the predictive validity of lay diagnostic interview schedule diagnoses in the general population. a comparison with physician examiners.a clinical reexamination by psychiatrists is a useful comparison for exploring lay diagnostic interview schedule-derived psychiatric diagnoses in general population surveys, but as a validity standard psychiatric reexamination is less than ideal. there are many potential sources of disagreement that have nothing to do with the validity of either the lay or the psychiatrist examination. another approach to comparing lay and psychiatrist diagnoses is to examine their relative predictive power. we ...20133689095
the association of acrylamide with proteins. the interpretation of fluorescence quenching experiments.the association properties of acrylamide with a number of proteins in aqueous solution have been investigated by a fluorescence-quenching method previously used in micelles and lipid bilayers (blatt, e., chatelier, r.c. and sawyer, w.h. (1984) chem. phys. lett. 108, 397-400). at ph 7.0, acrylamide partitions between the bulk aqueous phase and the proteins, human serum albumin, monellin and ovalbumin. comparison with an earlier method of analysis (sikaris, k.a., thulborn, k.a. and sawyer, w.h. (1 ...19863697370
spinal cord serotonin release and raised blood pressure after brainstem kainic acid injection.the recently developed technique of in vivo dialysis has permitted us to make direct measurements of serotonin release in a specific region of the spinal cord and to relate this to changes in blood pressure elicited by chemical stimulation of the brainstem. in the present experiments we have shown that chemical stimulation of bulbospinal neurons in the region of the b3 cell group in the ventromedial medulla, causes an increase in the release of serotonin in the thoracic spinal cord and that this ...19863697690
[effect of immobilization stress on the course of experimental influenza infection and the process of interferon formation].the experimental data on the peculiar features of interferon production in c57bl/6 mice, infected with the lethal dose of influenza virus and simultaneously subjected to the action of a stress factor, are presented. immobilization stress was found to exert pronounced influence on the interferon-producing system of the body, which was manifested by the appearance of alpha interferon in a titer of up to 1:80 in the blood of intact animals. 6-hour immobilization preceding infection did not accelera ...19863705812
successful treatment of aspermia secondary to obstruction of ejaculatory duct.a case is reported of a patient with aspermia secondary to bilateral ejaculatory duct obstruction. successful therapy was accomplished by use of the direct-vision urethrotome.20133716051
[causes of postoperative complications of graded anterior radial keratotomy]. 20133716074
adapting to changing attitudes towards food. 20133716140
initial management of cutaneous malignant melanoma.appropriate initial surgical management of primary cutaneous malignant melanoma is important since no effective treatment exists once the tumour metastasizes. the author reviews methods of initial treatment, excisional biopsy with adequate margins being the most common. he also reports results from a questionnaire survey on the type of microstaging used at hospitals across canada. two thirds of the pathologists who responded to the questionnaire preferred to use both clark's and breslow's method ...20133719498
rat cns neurons are not yet programmed to shorten their chromatin repeat length at the end of fetal neurogenesis.neurons from rat fetal cerebral hemispheres were grown in a synthetic medium (maat medium), as previously described, for different periods of time. the repeat length of their chromatin was determined by micrococcal nuclease digestion and compared with that of neurons isolated from postnatal rat brain of corresponding ages. in contrast to the in vivo situation, we found that neurons, dissociated at the 16th gestational day and cultured in vitro, did not undergo the shortening of their chromatin r ...19863719702
[effect of splenin on the concentration of biogenic amines in the tissues and blood plasma of the rat]. 19863721001
does placebo response mediate runner's high?it is proposed that runner's high is mediated by increased endorphin release as induced by placebo responses arising from subjective expectancies and setting.20133725516
analysis of factors involved in determining urinary bladder voiding cycle in urethan-anesthetized rats.the mechanism(s) involved in determining the voiding cycle of the rat urinary bladder have been investigated in urethan-anesthetized animals. fluid emission is almost confined to that phase of the voiding cycle which is characterized by the presence of a series of high-frequency oscillations in intraluminal pressure (iphfo). during this phase the mean urethral flow rate reached a maximum and fluid was expelled in a stream-like fashion. the index obtained by multiplying the amplitude of iphfo by ...19863740305
purification of the constituent enzyme fractions of mycobacillin synthetase.the final purification of the three-fraction enzyme complex mycobacillin synthetase was done by hydroxyapatite column chromatography and sucrose-density-gradient centrifugation; each of the fractions obtained migrates as a single component in sds/polyacrylamide-gel electrophoresis and gel electrofocusing. the mr of the enzyme fractions a, b and c by gel filtration is 260 000, 190 000 and 105 000, and that by sds/polyacrylamide-gel electrophoresis is 252 000, 198 000 and 108 000 respectively. non ...20133741392
thermal properties of water in myoglobin crystals and solutions at subzero temperatures.the water of hydration in myoglobin crystals and solutions was studied at subzero temperatures by calorimetry and infrared spectroscopy (ir). for comparison we also investigated glycine, dl-alanine and dl-valine solutions. the hydration water remains amorphous at low temperatures. we find a broad glass transition between 180 and 270 k depending on the degree of hydration. the ice component shows a noncolligative melting point depression that is attributed to a finite conformational flexibility. ...20133741983
relationships among duration of infusion, dose, dosing interval, and steady-state plasma concentrations during intermittent intravenous infusions: studies with metronidazole.relationships among duration of infusion (t), dose, dosing interval (tau), maximum and minimum plasma drug concentrations at steady state (cmax,ss and cmin,ss, respectively), and the duration of effective plasma concentrations (td) during multidose intermittent infusion regimens were studied by computer simulation using metronidazole as a model drug. pharmacokinetic parameter values for metronidazole were obtained from the literature and the minimum effective plasma concentration (mec) was taken ...20113746634
[hemoglobin g georgia in a turkish family in the netherlands]. 19863754310
computers in clinical laboratory management in singapore.in 1974, an off-line mini-computer system was introduced in the clinical biochemistry laboratories of the government department of pathology in singapore. with the resiting of the 24-hour emergency biochemistry laboratory on the same floor as the haematology department within the new singapore general hospital, an on-line computer system was installed in 1983 to serve both the emergency biochemistry and haematology laboratories. an almost identical on-line system was also purchased in 1984 to re ...20133754707
disappearance and effects of exogenous lipid transfer activity in rats.these studies were performed to determine the role of plasma lipid transfer activity in the regulation of plasma total and lipoprotein cholesterol in vivo. partially purified human lipid transfer activity was injected into rats at a level similar to that of normal rabbit plasma, d greater than 1.21. the disappearance of exogenous lipid transfer activity from rat plasma was biphasic, with a 70% loss within 6 h. the remaining 30% was lost with a half-time of about 14 h. in the rat, short-term expo ...19863768397
antibacterial interaction of cefuroxime and serum from uraemic patients.a strain of proteus rettgeri was exposed to combinations of subinhibitory concentrations of cefuroxime and serum from normal subjects and from uraemic patients (on conservative and on haemodialysis treatment) and the antibacterial activity of these was determined. cefuroxime and normal serum gave a synergistic effect. compared with controls, the combination of cefuroxime and uraemic serum from patients on conservative treatment showed a reduced inhibitory effect. the antibacterial activity of th ...19863771426
[frequency of isolation and drug resistance of bacterial strains from urine samples tested in the bacteriology and virology laboratory of the u.s.l. 10/d in florence].two thousand five hundred and sixty-eight positive monomicrobic urine samples (from general practice and hospital wards) were examined and isolated strains were tested against various antimicrobial drugs. our findings showed that urinary-tract infections caused by escherichia coli were the most common in females, whereas those by pseudomonas aeruginosa, proteus rettgeri, enterobacter species, other difficult gram-negative rods and streptococcus faecalis were in total the most common in males. if ...19863786667
[instrumental measurement of the anteroposterior laxity of the normal and lax knee]. 20133809655
[activation of protein c on the surface of cultivated endothelial cells--role of antithrombin iii]. 19863811501
synovial osteochondromatosis.synovial osteochondromatosis is a benign disorder in which cartilaginous loose bodies develop about the large joints, usually the knee. it is caused by synovial metaplasia of unknown etiology. symptoms are due either to mechanical problems caused by the loose bodies or to the degenerative arthritis that usually follows in several years. surgical or arthroscopic removal of the loose bodies appears to be the only effective treatment. loose bodies may recur, necessitating synovectomy.20133812170
fine needle aspiration biopsy in the diagnosis of thyroid cancer and thyroid disease.fine needle aspiration biopsy (fnab) performed for diffuse and nodular goiter in the past 5 years, was evaluated in 1399 cases. surgery was performed on the basis of fnab cytologic diagnosis that was positive or suggestive of malignancy and/or a suggestive clinical history. surgery also was performed in cases of cold nodules with negative fnab results that did not respond to 6 months of suppressive thyroxine therapy. a correlation of cytologic findings with histologic findings was possible in 41 ...20083815295
[schizophrenia and drug therapy]. 20133837887
[value of the cardiothoracic index in the evaluation of cardiac performance in dilated cardiomyopathies]. 20133838062
powerline frequency electric and magnetic fields: a pilot study of risk perception.the perception of the potential risk arising from human exposure to 50/60 hz electric and magnetic fields was studied with a quasi-random sample of 116 well-educated, opinion leaders using the risk perception framework previously developed by slovic, fischhoff, and lichtenstein. these individuals rated exposure to fields from transmission lines and electric blankets on a variety of scales that have been found useful in characterizing people's risk attitudes and perceptions. these judgments allow ...19853843677
an introduction to physical assessment for the nephrology nurse. 20133846448
[a comparative study. the older person too is an individual]. 20133850215
lung cancer in new zealand women. 20133856158
[cefotiam concentration in exudates from the drainage of patients with acute peritonitis following intravenous administration].cefotiam dihydrochloride (ctm) in a dose of 2 g was given by intravenous bolus injection to 15 patients operated upon for acute or subacute abdominal organs. they were included to 5 cases of acute localized peritonitis due to perforative appendicitis, 3 of diffuse peritonitis due to perforative duodenal ulcer, 1 of diffuse peritonitis with intestinal obstruction, 1 of perforative sigmoid colon cancer, 2 of gastric cancer or polyp with cholelithiasis, and 3 of cholangitis with cholecyst-choledoch ...19853862880
nystan pastilles. 20093866590
ceftriaxone against gram-negative and gram-positive bacteria: bactericidal and post-antibiotic effect.the effect of ceftriaxone against gram-negative and gram-positive strains of different clinical isolates has been compared to that of other cephalosporins such as cefuroxime, cefoxitin and cefotaxime. cefotaxime and ceftriaxone have a notably higher activity against enterobacteriaceae than cefuroxime and cefoxitin. if ceftriaxone activity is compared to cefotaxime activity, it may be seen that the former shows a stronger action against pseudomonas, proteus rettgeri, enterobacter and serratia. ag ...19853875430
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