Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| studies on the treponema pallidum immobilizing activity in normal human serum. 5. on the protective role against syphilis. | it was shown that t. pallidum immobilized in vitro by normal serum had lost its infectivity in rabbits. this finding suggested that the immobilizing activity of normal serum might play a role in the natural resistance of man against infections with t. pallidum. however, the results of serological studies of acquired early syphilis in man and of experimental syphilis in cynomolgus monkeys did not present evidence that the immobilizing activity of normal serum protected against syphilis infection. | 1976 | 826114 |
| studies on the treponema pallidum immobilizing activity in normal human serum. 6. antigenic relationship between t. pallidum and various mammalian tissues. | the immobilizing igm antibody of normal serum and the igg antibody of syphilis serum reacted with different antigens of t. pallidum. the normal serum antibody to t. pallidum cross-reacted with antigens of various mammalian tissues. | 1976 | 826115 |
| [effectiveness of rifampicin (rimactan) in the treatment of gonorrhea]. | 1976 | 829660 | |
| borderline and reactive fta-abs. results in lupus erythematosus. | fluorescent treponemal antibody absorption tests were performed on serum samples from 43 patients with lupus erythematosus (le). seven borderline and three reactive results were obtained from patients who had no evidence of syphilis, and treponema pallidum immobilization (tpi) tests were nonreactive. these probable nonsyphilitic reactions were associated with discoid le (dle) as frequently as with systemic le (sle). three of these serum samples were reactive in the microhemagglutination assay fo ... | 1977 | 831621 |
| electron microscopy of lymph nodes of hamsters experimentally infected with treponema pertenue. | the morphology of lymph node tissue from normal hamsters and from hamsters experimentally infected with treponema pertenue gauthier was compared by means of light and electron microscopy. the capsules of the lymph nodes from infected hamsters showed an increased thickness in comparison with those of the non-infected animals. the infected lymph nodes differed from normal lymph nodes by small accumulations of neutrophilic leucocytes in the cortical areas. in addition, the amount of intercellular c ... | 1977 | 835357 |
| enteropathogenicity of various isolates of treponema hyodysenteriae. | isolates of treponema hyodysenteriae from 25 geographically separated outbreaks of swine dysentery were tested for their ability to produce the disease. clinical signs and lesions typical of acute swine dysentery were produced in 52 of 68 (75%) susceptible specific pathogen-free pigs that had been orally inoculated with pure cultures of 23 of 25 beta-hemolytic isolates. in addition, 13 weakly beta-hemolytic isolates of nondysentery origin with morphology similar to t. hyodysenteriae did not prod ... | 1977 | 844908 |
| isolation of treponema hyodysenteriae from feces of pigs affected with swine dysentery by use of a medicated medium. | 1977 | 854087 | |
| glucose-1-phosphate as a selective substrate for enumeration of bacteroides species in the rumen. | when glucose-1-phosphate was used as the only added energy source in a selective roll tube medium, colony counts for rumen contents ranged from 17.8 to 84.8% of the total culturable count. percentages were highest in rumen contents from sheep fed high-concentrate rations. from a total of 73 cultures isolated from glucose-1-phosphate roll rubes, only 15.1% were presumptively identified as bacteroides species. strains presumptively identified as butyrivibrio, selenomonas, treponema, streptococcus ... | 1977 | 869544 |
| monocytosis in congenital syphilis. | we evaluated hematological findings, with special reference to the monocyte count, in ten infants with congenital syphilis. one patient had a monocytic leukemoid reaction and eight had absolute monocyte counts considerably higher than normal control infants. monocytes appear to be an essential participant in the cellular reaction to treponema pallidum. to our knowledge, this is the first report of a monocytic leukemoid reaction in congenital syphilis. | 1977 | 879114 |
| efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs. | in a series of experiments, weanling pigs (12 to 18 kg av weight) were inoculated by means of feed with scrapings and contents of dysenteric colons. mucohemorrhagic diarrhea developed in 97% of the infected, nonmedicated pigs, and 80% of these pigs died. prophylactic feed medication with nithiamide at dose levels of 600, 300, or 150 ppm beginning 2 days before inoculation to 28 days after inoculation prevented the development of swine dysentery and permitted performance equal to that of the noni ... | 1977 | 879561 |
| urease assay and urease-producing species of anaerobes in the bovine rumen and human feces. | a growth medium and test were developed for rapid detection of urease in fermentative anaerobic bacteria. using nonselective rumen fluid roll-tube agar medium and the new test, it was confirmed that peptostreptococcus productus is often the most numerous urease-forming species in human feces. also, some fecal strains of ruminococcus albus, clostridium innocuum, and clostridium beijerinckii produced urease. single strains of fusobacterium prausnitzii, coprococcus catus, and streptococcus mitis th ... | 1977 | 879770 |
| [the effect of calcium ion concentration on the sensitivity of the treponema pallidum immobilization test (tpi test)]. | 1977 | 899077 | |
| labeling patients with false-positive fta-abs. | 1977 | 901289 | |
| swine dysentery: inoculation of gnotobiotic pigs with treponema hyodysenteriae and vibrio coli and a peptostreptococcus. | pure cultures of treponema hyodysenteriae given orally to conventional pigs resulted in the development of swine dysentery, whereas identical cultures given to gnotobiotic pigs did not produce the disease. oral inoculation of gnotobiotic pigs with vibrio coli and/or a peptostreptococcus in addition to t. hyodysenteriae did not result in dysentery. neutralization of gastric secretions with nahco3 immediately prior to inoculation with t. hyodysenteriae increased the period during which treponemes ... | 1977 | 907906 |
| papulosquamous eruptions: usefulness of biopsy in establishing diagnosis. | papulosquamous dermatoses are caused by a variety of etiologic agents. t. rubrum in particular can produce clinicopathologic changes which mimic a spectrum of disorders. of these, some are papulosquamos in character. whenever patients are seen with atypical papulosquamous dermatoses, the clinical differential diagnosis should always include dermatophytosis caused by t. rubrum. if skin scrapings for direct microscopic examination and culture studies are negative, a biopsy should be seriously cons ... | 1977 | 923286 |
| treatment of seropositive primary syphilis: an evaluation of 196 patients. | one hundred seventy-five patients with primary infection with treponema pallidum were treated with benzathine penicillin g, 2.4 million units given intramuscularly weekly for two weeks for a total of 4.8 million units. twenty-one patients with primary syphilis who were allergic to penicillin were treated with oral tetracycline, 500 mg four times daily for 12 days for a total of 24 gm. all 196 patients had resolution of their lesions, and all were seronegative within one year. white patients pres ... | 1977 | 929349 |
| [evaluation of the specificity of the kolmer's test compared with the treponema immobilization test]. | 1977 | 930320 | |
| [nephrotic syndrome, hepatitis and circulating anticoagulant in secondary syphilis]. | 1977 | 931239 | |
| [syphilis serodiagnosis]. | 1976 | 968790 | |
| the effects of glucosamine derivatives on the growth of cultivable treponema. | the effects of glucosamine and its derivatives on the growth of treponema phagedenis biotypes reiter and kazan 5 were studied to determine if these agents could act as growth stimulants for organisms of the genus treptonema. growth studies on the cultivable treponemes were conducted in culture tubes containing glucosamine, glucosamine derivatives, and (or) glucose and galactose in serum-based media. glucosamine and n-phenylacetylglucosamine were definitely inhibitory to growth at the concentrati ... | 1976 | 974903 |
| arginine catabolism by treponema denticola. | treponema denticola, an anaerobe commonly present in the human mouth, ferments various amino acids and glucose. amino acid analyses indicated that substrate amounts of arginine were utilized by t. denticola growing in a complex, serum-containing medium. cell suspensions metabolized l-arginine to citrulline, nh3, co2, proline, and small amounts of ornithine. co2, nh3, ornithine, and proline were produced from l-citrulline by cell suspensions. determinations of radioactivity in products formed fro ... | 1976 | 977548 |
| passive hemolysis test for antibody to treponema hyodysenteriae. | swine were infected orally with pure cultures of treponema hyodysenteriae, and the humoral antibody response was measured by a passive hemolysis test (passive hemagglutination test with the use of complement). antibody to t. hyodysenteriae was detected as early as 1 week and later on at 4 months after exposure. however, peak serum titers were obtained after challenge at 4 weeks postinfection. the usefulness of the test as a potential diagnostic tool for antibody to t. hyodysenteriae is discussed ... | 1976 | 992870 |
| [the treponema pallidum immobilization test (tpi) and possibilities of its standardization (proceedings)]. | 1976 | 997703 | |
| activity of various compounds against a pathogenic strain of treponema hyodysenteriae. | a test method for in vitro investigations of chemotherapeutics against a pathogenic strain of treponema hyodysenteriae is described. the sensitivity of this organism against various compounds especially against the pleuromutilin derivative 81723 hfu, a new antibiotic, was evaluated. | 1976 | 998032 |
| [lysozyme content in the serum and organs of rabbits with a syphilitic infection]. | the levels of lysozyme in the serum and organs of shienshilla male rabbits infected with nico-s treponema were determined. the studies showed that the lues infection affected the factors of non-specific immunity, which was evident from the changes in the lysozyme titer. administration of benzylpenicillin resulted in a marked decrease in the lysozyme titer in all cases. the experiments are indicative of advisability of studying the use of crystalline lysozyme in combination with antibiotics for i ... | 1976 | 999268 |
| accidental laboratory infection with treponema pallidum, nichols strain. | this case report describes a laboratory-acquired infection with treponema pallidum, nichols strain. the specific details of the accidental exposure are presented, along with a description of the clinical observations. this infection indicates that the rabbit adapted nichols strain of t pallidum retains its capability to infect humans. in addition, aerosols of concentrated preparations of these organisms, generated within the laboratory, represent a definite biohazard. | 1976 | 1010772 |
| diagnosis of swine dysentery: spirochaetes which may be confused with treponema hyodysenteriae. | spirochaetes, designated pws, microscopically resembling treponema hyodysenteriae, were isolated from the colon contents of pigs with post-weaning scours from three herds, which on clinical and epidemiological grounds were thought to be free from swine dysentery. one of the isolates was fed to pigs experimentally but no evidence of disease was noted. their cultural characteristics differed from those of t hyodysenteriae but they were similar to those of a non-pathogenic spirachaete (4/71) which ... | 1976 | 1014306 |
| lupus erythematosus and reactive tests for syphilis: update. | sera of patients with lupus erythematosus can produce false-positive reactions in most serologic tests for syphilis, including the fta-abs test. false-positive reactions in the fta-abs test can exhibit beaded, borderline or reactive patterns of fluorescence. beaded fluorescence is commonly associated with anti-dna antibody and other correlates of lupus activity. borderline and reactive results are common in both systemic and discoid lupus erythematosus, and are usually not associated with increa ... | 1976 | 1017253 |
| jarisch-herxheimer reaction. case report. | the jarisch-herxheimer reaction is a response to the treatment of syphilis. the most common findings are fever, malaise, headache, and exacerbation of cutaneous lesions. the reaction is thought to be due to the effects of treponema breakdown products, and it should not be confused with an allergic reaction to the antibiotic employed. thus, further therapy must not be withheld. treatment is symptomatic. | 1976 | 1018353 |
| swine dysentery: protection of pigs by oral and parenteral immunisation with attenuated treponema hyodysenteriae. | an attenuated strain of treponema hyodysenteriae was used to immunise 18 pigs in three experiments. live attenuated spirochaetes were dosed orally and injected intra-peritoneally, and killed spirochaetes were injected intramuscularly with adjuvant. the vaccinated pigs, which developed high serum agglutination titres against t hyodysenteriae, and 18 unvaccinated litter-mates were repeatedly challenged with virulent t hyodysenteriae. nine vaccinated pigs and 16 control pigs developed typical swine ... | 1976 | 1030823 |
| [studies of sera yielding biologically false reagin test results and sera from patients with autoimmune diseases and neoplasms. treponemal tests]. | 1976 | 1032179 | |
| letter: dark-field examination in early primary syphilis. | 1975 | 1088960 | |
| syphilitic proctitis in a homosexual. | 1975 | 1088965 | |
| current status of the treatment of syphilis. | penicillin remains the treatment of choice for syphilis, with sustained low blood levels curing virtually all patients having early syphilis and halting disease progression in most patients with symptomatic syphilis. tetracycline, erythromycin or cephalothin yields similar cure rates for patients with early syphilis who are allergic to penicillin. the efficacy of non-penicillin regimens for the treatment of late syphilis is uncertain. results of venereal disease research laboratory (vdrl) or oth ... | 1975 | 1089007 |
| immunopathogenesis of syphilitic glomerulonephritis. elution of antitreponemal antibody from glomerular immune-complex deposits. | a renal biopsy was performed on a patient with syphilitic glomerulonephritis characterized clinically by the acute onset of nephrosis that responded dramatically to penicillin therapy. histologic, electron microscopical and immunohistochemical studies revealed an early membranous glomerulonephritis characterized by the presence of subepithelial basement-membrane deposits containing igg and c3. the glomerular lesion, however, differed from that in the usual case of membranous nephropathy in that ... | 1975 | 1089888 |
| macrophage migration inhibition test in untreated syphilis. | two modifications of macrophage migration inhibition test, one of george and vaughan and the other one of svejcar, were performed on a total of 78 cases of untreated syphilis at various stages. as specific antigens were used: treponema pallidum ultrasonate and cardiolipin. inhibition of migration was observed in 87 percent patients with primary syphillis and in all patients with late and late congenital syphilis. after improving and standardisation of the technique of treponema pallidum antigen- ... | 1975 | 1090263 |
| syphilis--diagnosis and treatment. | 1975 | 1091382 | |
| value and limitations of nontreponemal and treponemal tests in the laboratory diagnosis of syphilis. | 1975 | 1091384 | |
| treponema pallidum (nichols strain) in tissue cultures: cellular attachment, entry, and survival. | the interaction of treponema pallidum (nichols strain) with cultured cells was investigated under aerobic conditions. cell monolayers derived from rabbit testicular tissue extended the survival of treponemes as indicated by active motility. large numbers of organisms rapidly attached to cultured cells. within 3 h, one to twelve actively motile treponemes were attached to 25 to 50% of the cells. in addition, t. pallidum attained intracellularity as early as 30 min after inoculation of the cell mo ... | 1975 | 1091562 |
| [persistance of treponema palldium after treatment during experimental and human syphilis]. | 1975 | 1092242 | |
| isolation of the spirochetes in the perilymph despite prior antisyphilitic therapy: a case report. | for the congenital syphilitic patient to develop sensorineural deafness is uncommon. for the congenital syphilitic patient to have persistence of treponemes after treatment is rare. to demonstrate viable organisms in the inner ear perilymph of the congenital syphilitic patient, despite treatment with penicillin, has not been recorded to date. this is a case report of such a patient. | 1975 | 1092291 |
| treponema pallidum in nerve fibres. | ultrathin sections of a rabbit scrotal syphiloma were examined by electron microscopy. treponemes were observed in the endo-, peri-, and epineurium of the nerve fibre. the significance of these findings, in that infection may be transmitted via the nerve fibres and pain reduced by damage to the afferent fibres, are discussed. | 1975 | 1092423 |
| the fluorescent treponemal antibody-absorption (fta-abs) test for syphilis. | the fta test was developed at a time when immunofluorescence procedures were not well-defined. through technique control and research, a modification of the fta test, the fta-abs, has attained a position as one of the leading treponemal tests to confirm the reagin tests for syphilis. in this review of the fta-abs test, attention has been focused on reagent development, with the anticipation that reagent standardization may soon become a reality. the t. pallidum antigen obtained by extracting inf ... | 1975 | 1092525 |
| syphilitic gastropathy. | a case study of a 22-year-old male with periumbilical, postprandial pain, partially relieved by antacids is presented. abnormalities demonstrated on upper-gastrointestinal series and a positive fta-abs suggested gastric lues. this diagnosis was confirmed by demonstrating spirochetes in gastric mucosa, both by silver impregnation and fluorescent techniques specific for treponema pallidum. | 1975 | 1093394 |
| letter: screening for treponemal infection. | 1975 | 1093635 | |
| clinical value of the treponema pallidum haemagglutination test. | in 1,129 patients attending the department for sexually transmitted diseases, the serum was examined by three screening tests (vdrl slide, rpcf, and tpha) and twelve cases of syphilis (1 per cent. of patients attenting the clinic) were discovered. six of these patients were considered to have latent syphilis (5 acquired, 1 congenital) and were detected only by the tpha; all six cases were confirmed by the fta-abs, the tpha failed to detect three of the remaining six cases (2 primary and 1 very e ... | 1975 | 1093636 |
| [study of serologic reation in syphilis with thermoresistors, using a specific treponema antigen]. | 1975 | 1094763 | |
| a study of yaws among pygmies in cameroon and zaire. | in a survey of 333 pygmies in the cameroon 4.5 percent. were found to have clinical evidence of yaws. this was also found in 10 per cent. of the inhabitants of camps in zaire. the results of vdrl and fta-abs tests on a sample of the population are presented. these provide evidence of a very high incidence of treponemal disease, 80 to 90 percent. of the population showing serological evidence of infection. active transmission is taking place in both areas but more frequently in zaire. | 1975 | 1095143 |
| failure to infect gnotobiotic colostrum-deprived, and normal piglets with treponema pallidum (nichols). | normal piglets kept at 16 degrees c. and gnotobiotic piglets kept at 32 degrees c. rapidly destroyed treponema pallidum, while gnotobiotic piglets kept at 26 degrees c. showed slightly slower clearance. no infections were established. the high body temperature of the piglets has an important influence on the survival of t. pallidum. | 1975 | 1095145 |
| lymphocyte transformation in syphilis: an in vitro correlate of immune suppression in vivo? | suppression of cellular immunity during primary and secondary infection may explain, in part, the unusual clinical evolution of syphilis. we have previously shown that lymphocytes from normal subjects undergo blastic transformation when exposed in vitro to treponema refringens. this response was suppressed in patients with syphilis. the suppression being unrelated to serum factors. in the present paper we studied lymphocyte response in vitro to t. refringens, t. reiter, and t. pallidum as well a ... | 1975 | 1095482 |
| isolation and purification of treponema pallidum from syphilitic lesions in rabbits. | treponema pallidum were extracted from testicular syphilomas of corticosteroid-treated rabbits and purified by differential centrifugation. the steroid therapy allowed a longer holding time for infected rabbits, which produced greater treponeme yields, averaging 1.58 x 10(10) treponemes per rabbit. the treatment, which also diminished cellular infiltration and increased the extracellular mucoid material in lesions, produced much cleaner suspensions than preparations from nontreated animals. most ... | 1975 | 1095485 |
| [the fta-abs igm test in treated and untreated acquired syphilis]. | 1975 | 1096243 | |
| [treponema pallidum in peripheral nerves of rabbit syphiloma]. | 1975 | 1096485 | |
| erosive gastritis as a manifestation of secondary syphilis. | in a case of secondary syphilis with gastric involvement, the clinical history and roentgenographic and gastroscopic examiniations initially suggested an infiltrative malignant neoplasm. however, macroscopic and histologic examination of the partial gastrectomy specimen demonstrated an erosive, inflammatory lesion. subsequently, numerous treponema pallida were demonstrated in formalin-fixed eroded gastric mucosa by silver impregnation and fluorescent antibody technics. although the true incidenc ... | 1975 | 1096590 |
| inactivation of treponema pallidum by silver sulfadiazine. | silver sulfadiazine, an anti-infectious agent for the prevention and treatment of burn sepsis, has been found to possess antitreponemal activity against treponema pallidum. at 28 c, complete inactivation of the organism was produced by exposure of the organism to a concentration of 50 mug of the drug per ml for 1 to 5 min, 12 to 25 mug/ml for 10 to 15 min, and 6.2 mug/ml for 30 min. at 37 c, the amounts of silver sulfadiazine required for inactivation were two- to fourfold less. | 1975 | 1096803 |
| a reappraisal of the value of the igm fluorescent treponemal antibody absorption test in the diagnosis of congenital syphilis. | to re-evaluate the usefulness of the igm fluorescent treponemal antibody absorption test in the diagnosis of congenital syphilis, three groups of infants were investigated. group 1 infants showed that the test was always negative in normal neonates born to seronegative mothers. from group 2 infants we determined the standardization of the test using commercially prepared conjugate to allow the maximum exclusion of false positive and negative results. studies on group 3 neonates confirmed that th ... | 1975 | 1097616 |
| the direct fluorescent antibody test for the detection of treponema hyodysenteria in pigs. | a direct fluorescent antibody technique for the detection of treponema hyodysenteriae in faeces and bowel smears from pigs produced a better preparation than the indirect method and also had the advantages that it took less time, produced less non-specific fluorescnece and gave direct control over the availability of the reagents used. | 1975 | 1098120 |
| [hemagglutination reaction in the serodiagnosis of syphilis]. | 1975 | 1098299 | |
| [hard chancre as a manifestation of cellular immunological reactions at the site of entry of spirochaete pallida]. | 1975 | 1098300 | |
| [characteristics of the morphogenesis of treponema pallidum l forms and the stages of their reversion]. | 1975 | 1098302 | |
| [discovery of treponema pallidum (on the 70th anniversary)]. | 1975 | 1098306 | |
| application of the enzyme-linked immunosorbent assay (elisa) in the serodiagnosis of syphilis. | the enzyme-linked immunosorbent assay (elisa) technique, using an ultrasonicate of treponema pallidum as antigen, has been evaluated as a serological test for syphilis. it is concluded that the test is simple, reliable, and relatively quick and that its sensitivity in all stages of syphilis is equal to the ftaabs test. because its specificity is probably also high, elisa might be used in future as a first-line screening test for the serodiagnosis of syphilis. | 1975 | 1098730 |
| chemical studies on the cell walls of leptorspira biflexa strain urawa and treponema pallidum strain reiter. | the preparation and chemical properties of the cell walls of leptospira biflexa urawa and treponema pallidum reiter are described. both cell walls are composed mainly of polysaccharides and peptidoglycans. the data of chemical analysis indicate that the cell wall of l. biflexa urawa contains rhamnose, arabinose, xylose, mannose, galactose, glucose and unidentified sugars as neutral sugars, and alanine, glutamic acid, alpha, epsilon-diaminopimelic acid, glucosamine and muramic acid as major amino ... | 1975 | 1099288 |
| [isolation of pathogenic nichols's treponema strains with altered sensitivity to penicillin by means of in vivo experiments in rabbits]. | 1975 | 1099622 | |
| a more complete evaluation of the color-coded antigen for the automated reagin test. | a comparative study, on 500 samples, of the toluidine red antigen, one of the low-cost, color-coded antigens for the automated reagin test, shows a greater sensitivity than the rapid plasma reagin card antigen. | 1975 | 1100664 |
| spontaneous reversion of fta-abs test reactions. | in a series of 56 clinically healthy persons with no history of syphilis and negative vdrl tests but reactive fluorescent treponemal antibody absorption (fta-abs) tests, 20 spontaneously developed nonreactive fta-abs tests in a period of eight months or less. all but one of these had been of 2+ or less fluorescence. in such a situation, the serologic tests for syphilis (vdrl and fta-abs tests) should be repeated at intervals for up to a year before coming to a decision regarding the diagnosis of ... | 1975 | 1100871 |
| [the tpha test. methods]. | 1975 | 1101310 | |
| a comparison between sorbent and reiter sonicate in the absorbed fluorescent treponemal antibody test. | some syphilitic sera still fluoresce with reiter treponemes as the antigen after treatment with the sorbent used in the fta-abs test; this finding indicates incomplete removal of group antitreponemal antibody. levels of this antibody in normal sera have been studied in relation to the titration of sorbent for use in the test. a comparison has been made of the results of fta-abs tests with sorbent and reiter sonicate and the tpi test on 1141 selected problem sera. results with the sonicate displa ... | 1975 | 1101780 |
| the specificity of fetal igm: antibody or anti-antibody? | reference materials were produced to standardize the immunoglobulin class specificity and potency of immunofluorescent anti-igm conjugates used for diagnostic tests for congenital syphilis. in attempting to mimic essential immunologic characteristics of syphilitic and nonsyphilitic infant sera, we evaluated these sera in comparison with processed adult sera. we were quite surprised to discover that some syphilitic babies do not produce significant quantities to igm antibody to t. pallidum in res ... | 1975 | 1101788 |
| [use of the direct fta-abs test in early syphilis patients]. | 1975 | 1102358 | |
| effects of oxygen and nitrogen on the character of t. pallidum is subcutaneous chambers in mice. | nitrogen and oxygen gases were injected into mouse subcutaneous chambers which contained virulent treponema pallidum. the effect of each gas on the viability and survival of t. pallidum in an in vivo system was determined. in comparison with the effects in nontreated control mice, injection of nitrogen enhanced both motility and survival time, but oxygen exerted a deleterious effect. | 1975 | 1104074 |
| false positive fta-abs results in patients with genital herpes. | 1975 | 1104075 | |
| [syphilitic lymphadenitis]. | the authors subjected to histological examination a total of 38 inguinal lymph nodes from 35 patients. in 34 instances recent acquired syphilis was involved in one instance tertiary syphilis. the disease was in all patients confirmed by clinical examination, by evidence of treponema pallidum in the luetic ulcer of the primary stage or in condylomas of the secondary stage and on serological examination by a positive bwr in blood or a positive tpi test. in three instances the histological finding ... | 1975 | 1104203 |
| igg subclasses of fluorescent treponemal antibodies: correlation with complement fixation and clinical stage. | 1975 | 1104227 | |
| carbon sources utilized by virulent treponema pallidum. | carbon sources utilized by virulent treponema pallidum organisms extracted from infected rabbit tissue have been investigated. utilization of 14c-labeled compounds by t. pallidum was monitored by degradation of these compounds to 14co2. experiments have consistently shown that of 22 carbon sources examined, [14c]glucose and [14c]pyruvate are selectively degraded to 14co2 under the experimental conditions employed. when [1-14c]pyruvate, [2-14c]pyruvate, and [3-14c]pyruvate are tested, virulent t. ... | 1975 | 1104482 |
| retention of motility and virulence of treponema pallidum (nichols strain) in vitro. | a maintenance medium for treponema pallidum was designed to hold its eh at the optimum for that organism, -10 to -110 mv. after 100% motile (freshly harvested) t. pallidum was inoculated into the medium, the motility of the treponemes decreased to 80% after 2 days, 50% after 3.5 days, and 0% after 9 days during incubation at 34 c. full virulence was retained for 2 days, but it dropped rapidly thereafter, and the treponemes became avirulent by day 5. | 1975 | 1104483 |
| [serologic diagnosis of syphilis by the passive hemagglutination test]. | the passive haemagglutination test in the diagnosis of syphilis was used with: 139 sera posing serological problems, 965 sera from subjects with syphilis at all stages of the disease and non-syphilitics. the percentages of agreement seen both in comparison of thpa with the tpi (94,5 p.cent) and the fta abs test (97 p.cent) demonstrate its high degree of specificity and sensitivity. the reaction may be performed rapidly on a routine basis and requires little in the way of specialised material. th ... | 1975 | 1105415 |
| pleural effusion disease in rabbits, clinical and post mortem observations. | in denmark and probably in other countries as well, the infectious agent causing intercurrent death of rabbits by passages of nichols pathogenic treponema pallidum has been studied in rabbits in the absence of t. pallidum. this agent can be propagated in rabbits at intervals of 2 to 30 days and, depending on the interval between passages and the number of passages, the mortality may vary from zero to almost 70 per cent. based on the post mortem findings in fatal cases, the name pleural effusion ... | 1975 | 1106115 |
| the laboratory diagnosis of syphilis. new concepts. | although new tests for syphilis, as well as new applications of standard tests, continue to appear, the usefulness of several of these procedures has not been determined. when the fluorescent treponemal antibody-absorption (fta-abs) test is used to screen for syphilis, the proportion of positive results that are true positives decreases. the value of modified fta tests in the diagnosis of neurosyphilis and congenital syphilis remains unproved. although not studied as extensively as the standard ... | 1975 | 1106283 |
| the diagnosis of syphillis. | 1975 | 1107771 | |
| tropical ulcers. | we review 230 cases of tropical ulcers, includied reports of 7 cases with squamous cell carcinoma. we think the etiology may be a combination of the hot, humid environment, trauma, local infection, and malnutrition. agressive treatment of these ulcers is advocated, to heal the wounds and to prevent malignant transformation. | 1975 | 1118492 |
| [serolgical tests for syphilis during pregnancy]. | 1975 | 1131933 | |
| survival of certain pathogenic organisms in swine lagoon effluent. | six pigs from a closed herd with no evidence or history of salmonellosis or swine dysentery were fed effluent from an anaerobic lagoon on a farm where salmonellosis and swine dysentery were enzootic. salmonella saint-paul was isolated from the effluent and fromthe feces and certain tissues of the pigs. clinical signs typical of swine dysentery and enteric shedding of large numbers of spirochetes with the characteristics of treponema hyodysenteriae were noted in 5 of the 6 pigs. | 1975 | 1133078 |
| the possibility that campylobacter (vibrio) coli and treponema hyodysenteriae are both involved in swine dysentery. | 1975 | 1139284 | |
| swine dysentery: pathogenicity of treponema hyodysenteriae. | when pure cultures of treponema hyodysenteriae were orally inoculated into pigs, severe disease characteristic of swine dysentery developed. less severe lesions were produced by oral inoculation of infective minced colon. noninoculated pigs were used as controls. inoculations of surgically isolated porcine colonic loops with either pure cultures or infective minced colon produced lesions only in the injected loop; the adjacent noninjected colon remained normal. pigs and other experimental animal ... | 1975 | 1147363 |
| [nonspecific immunity factors in syphilis]. | 1975 | 1154877 | |
| brief report. separation of pathogenic treponema pallidum from host rabbit tissue to obtain virulent and viable microorganisms. | t. pallida extracted from infected rabbit testes were purified from different tissue particles by equilibrium density centrifugation at 25 degrees c after layering on a column of ficoll-sodium metrizoate solution. after centrifugation, 32 per cent of the treponemes were present in a visible band and about 57 per cent were concentrated in the three ml suspension just above the interface between the ficoll-na metrizoate cushion and treponeme-containing medium. the treponemes were viable, virulent ... | 1975 | 1155111 |
| the isolation of a treponema hyodysenteriae-like organism associated with swine dysentery in norway. | 1975 | 1180192 | |
| morphology and physiology of spirochaeta aurantia strains isolated from aquatic habitats. | 1. seven strains of spirochaeta aurantia were isolated from pond and swamp water by means of a selective technique which utilized the ability of these organisms to move through bacterial filters and to diffuse through agar media. although most of the isolations were accomplished when enrichment media low in carbohydrates were used, all seven strains were found to be exclusively saccharolytic. 2. the isolates could be divided into two groups on the basis of cell morphology: a loosely coiled group ... | 1975 | 1190952 |
| comparison of the counter-immunoelectrophoresis technique with the reiter protein and three other serological tests as a first line test for syphilis. | the counter-immunoelectrophoresis technique with the reiter protein (rp-cie) was compared with two complement fixation tests (kolmer and rpcf) and a flocculation test (vdrl) in sensitivity and specificity. of the 1,927 consecutive attendants of a venereal disease clinic whose serum samples were used, 250 were considered to be syphilitic. the number of true-positive and false-positive reactions were: 121 and 4 (vdrl), 124 and 2 (kolmer), 179 and 41 (rpcf), 166 and 16 (rp-cie). the vdrl and the rp ... | 1975 | 1194403 |
| aetiology and pathogenesis of swine dysentery -- recent advances. | 1975 | 1200933 | |
| [serological total diagnosis of syphilis]. | 1975 | 1204901 | |
| a comparative quantitative evaluation of vdrl and treponema pallidum haemagglutination tests. | 1975 | 1213738 | |
| syphilitic hepatitis: clinical, immunological and morphological aspects. | in 17 out of 176 cases of early syphilis (seropositive syphillis i; syphilis ii) liver function tests yielded a positive result. in these patients a significant increase in the serum igg, igm and coeruloplasmin levels and a decrease in t4e transferrin level was found. the concentrations of alpha-2-macroglobulin and of beta-1-c-globulin were practically uneffected. liver biopsy revealed hepatitis of variable severity in 13 patients with focal necroses or a proliferative process effecting the wall ... | 1975 | 1235223 |
| the lipids of four unusual non-pathogenic host-associated spirochetes. | the lipid compositions of two spirochetes isolated from the human oral cavity and two isolated from pig feces were examined. these isolates were unusual in that they did not require long-chain fatty acids for growth, as do the other host-associated spirochetes, but rather required isobutyric and valeric acids. therefore, they could be cultured in a medium free of serum or fatty acid - albumin supplements. the major fatty acids synthesized were normal and iso fatty acids with 14 and 16 carbons. n ... | 1975 | 1238163 |
| treponeme outer envelope: chemical analysis. | the chemical composition of the outer envelope (oe) of treponema phagedenis biovar kazan 5 was investigated. after cultivation in a lipid-defined medium, the oe was removed from the cells with 0.7 mm sodium dodecyl sulfate. the solubilized oe was reaggregated by dialysis against 20 mm mgcl2, washed, lyophilized, and subjected to chemical analysis. the average yield of oe was 14.6% of the whole cell (wc) dry weight. the magnesium content was 0.683 mug/mg oe. peptidoglycan components such as muram ... | 1976 | 1250863 |
| [serologic tests in late symptomatic syphilis]. | 1976 | 1265303 | |
| serological tests in cerebrospinal fluid for congenital syphilis in central africa. | serological tests were performed in the cerebrospinal fluid (csf) of 13 children with active congenital syphilis (presence of specific igm fta-abs antibodies) and of seven seropositive children with no active syphilis (fta-abs igm-negative) born to syphilitic treated mothers in libreville, gabon. antibodies against treponema were measured by the venereal disease research laboratory test (vdrl), the treponema pallidum haemagglutination assay (tpha) and the fluorescent treponema antibody absorptio ... | 1992 | 1280042 |
| molecular characterization of serpulina (treponema) hyodysenteriae isolates representing serotypes 8 and 9. | the study described here was carried out to further characterize reference strains of serpulina (treponema) hyodysenteriae representing serotypes 8 and 9. results obtained from restriction fragment length polymorphism analysis, enteropathogenicity testing, and endotoxin profiles confirmed their identifications. electron microscopy indicated that both strains were covered with a thin layer of capsule-like material. immunoblot analysis indicated that an antigen in the 19-kda region of proteinase k ... | 1992 | 1280646 |
| treponema pallidum membrane protein a elisa: a new test for screening and diagnosis of syphilis. | a new elisa test system for screening antibodies directed against treponema pallidum is presented. the elisa is based on a recombinant dna-derived t. pallidum membrane protein a (tmpa). it makes the production of the kit easier as it abandons the necessity to culture t. pallidum in living animals. the specificity and sensitivity of the elisa are comparable with those of the tpha and fta-abs. the test gives only a positive result when there are antibodies against the tmpa antigen and, therefore, ... | 1992 | 1284776 |