Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| lcd versus crt displays: a comparison of visual search performance for colored symbols. | visual search performance for tactical symbols was examined with liquid-crystal (lcd) and cathode-ray tube (crt) displays. twenty-four adult participants (19 men, 5 women; mean age 41 years) searched for navy tactical display symbols on a map background. lcd and crt displays of similar size and resolution (52 cm diagonal, 1280 x 1024 pixels) were used. viewing angle (0 degrees vs. 60 degrees of azimuth), set size, target color (blue, red, or white), target presence, and search type (feature vs. ... | 2002 | 12452269 |
| air pollution induces heritable dna mutations. | hundreds of thousands of people worldwide live or work in close proximity to steel mills. integrated steel production generates chemical pollution containing compounds that can induce genetic damage (1, 2). previous investigations of herring gulls in the great lakes demonstrated elevated dna mutation rates near steel mills (3, 4) but could not determine the importance of airborne or aquatic routes of contaminant exposure, or eliminate possible confounding factors such as nutritional status and d ... | 2002 | 12473746 |
| inter- and intra-observer reliability of calculating cumulative lumbar spine loads. | the aim of this study was to quantify the precision of manual video digitization of three typical industrial tasks, as evaluated by the comparison of four cumulative kinetic parameters at the l4/l5 intervertebral joint: compression, joint shear, reaction shear and moment. ten observers were recruited (five male and five female), with an undergraduate background in human anatomy. on each of three test days, each observer digitized five repeats of each of three typical industrial lifting tasks of ... | 2002 | 12487691 |
| desired elements of hiv testing services: test recipient perspectives. | thematic analysis of transcripts from interviews with a purposive sample of 39 voluntary human immunodeficiency virus (hiv) test recipients in ontario (selected on the basis of hiv serostatus, risk behaviors, region of residence, gender, and testing format) was used to identify elements of hiv testing services of concern to test recipients. colleague review was used to ensure dependability of findings, and emergent themes were compared with the existing literature on patient satisfaction. data a ... | 2002 | 12513902 |
| factors influencing childhood influenza immunization. | following the launch of a publicly funded influenza immunization program for all residents of ontario over the age of 6 months, we evaluated 203 parents of children who presented to our emergency department between january and march of the following year (2001). overall, 54 (27%) of the children had been vaccinated. parents of non-immunized children were more likely to believe that immunization resulted in a flu-like illness (42% v. 17%; p = 0.001), caused side effects that were more severe than ... | 2003 | 12515783 |
| regional distribution of antibodies to herpes simplex virus type 1 (hsv-1) and hsv-2 in men and women in ontario, canada. | this study estimated the regional and age- and gender-specific seroprevalences of herpes simplex virus type 1 (hsv-1) and hsv-2 in ontario, canada. stored serum specimens from subjects aged 15 to 44 years, including men (n = 979), women not under prenatal care (n = 638), and women under prenatal care (n = 701) submitted for routine viral serology were randomly selected according to regional population size from public health laboratories. hsv-1 and hsv-2 testing was done with the mrl enzyme immu ... | 2003 | 12517830 |
| delayed application of condoms is a risk factor for human immunodeficiency virus infection among homosexual and bisexual men. | the objective of this analysis was to identify risk factors for recent human immunodeficiency virus (hiv) infection among homosexual and bisexual men in ontario, canada, during 1998-2001. participants were recruited through the provincial hiv diagnostic laboratory and through physicians and community organizations. hiv test results were used to identify recent seroconverters (cases). a subsample of 183 men (62 cases and 121 controls) enrolled in the polaris hiv seroconversion study as of june 20 ... | 2003 | 12543620 |
| glucose intolerance in children with cystic fibrosis. | to evaluate the relations among glucose intolerance, genotype, and exocrine pancreatic status in patients with cystic fibrosis (cf). | 2003 | 12584532 |
| rural nonphysician providers' perspectives on palliative care services in northwestern ontario, canada. | most palliative care in rural remote areas is provided by nonphysicians. this paper reports a survey of interdisciplinary rural health service providers (not including physicians) to identify the strengths and weaknesses in palliative care service delivery in a rural and remote region in northwestern ontario, canada. questionnaires were sent to 156 nurses, homemakers, social workers, and pastoral care workers who care for terminally ill persons and their families, and 122 were completed and retu ... | 2003 | 12585775 |
| incidence, clearance and predictors of human papillomavirus infection in women. | persistent infection with carcinogenic human papillomavirus (hpv) is linked to high-grade lesions and cervical cancer. to better understand the natural history of hpv, we sought to determine the rates of incident and cleared carcinogenic hpv infection, by age, among women aged 15-49 years and to explore risk factors for incident infection. | 2003 | 12591782 |
| oseltamivir for treatment of influenza in healthy adults: pooled trial evidence and cost-effectiveness model for canada. | influenza is a common viral respiratory infection that is associated with significant morbidity. oseltamivir (tamiflu) is a neuraminidase inhibitor-a new class of antiviral treatment for influenza where efficacy and safety has been established but cost-effectiveness is unknown. | 2003 | 12641862 |
| the olivieri report--a compelling study of the growing tensions in clinical research. | 2003 | 12645235 | |
| wombs for rent: an examination of prohibitory and regulatory approaches to governing preconception arrangements. | on october 9, 2002, bill c-13 had its first reading in the canadian house of commons. bill c-13 was in the same form as bill c-56 of the first session of the thirty-seventh parliament, which had its first reading on may 9, 2002. bill c-13, an act respecting assisted human reproduction, prohibits the practice of commercial surrogacy or preconception agreements in canada, under threat of criminal sanction. in the first half of the article, the author discusses the deficiencies of the bill's prohib ... | 2003 | 12674583 |
| impact on blood pb levels of maternal and early infant feeding practices of first nation cree in the mushkegowuk territory of northern ontario, canada. | exposure to pb in-utero and in infancy has been associated with cognitive risk, even at low blood pb levels of 0.48-0.96 micromol l(-1). based on the hypothesis that wild game consumed by first nation women of mushkegowuk territory contains pb that might be transferred through blood or breast-milk to the fetus or infant, the study's objectives were to describe: (1) pb in maternal and cord blood at birth and infant blood at 4 months, and (2) dietary influence on pb status. cord and maternal pb we ... | 2003 | 12729262 |
| emancipatory responses to oppression: the template of land-use planning and the old order amish of ontario. | in this paper i discuss the clash of values between the old order amish community of ontario and the dominant social paradigm in agriculture. land-use and agricultural regulations, designed for an industrial style of agriculture, are experienced as a threat to the survival of the old order amish agricultural social economy and community. the paper describes how i have worked with the old order amish to respond to these challenges and to create public policies that will allow them to maintain the ... | 2003 | 12741697 |
| seeing double, thinking twice: the toronto drag kings and (re-) articulations of masculinity. | through a close reading of the performances of masculinity by the toronto drag kings, this chapter argues that drag king shows parody the hyper-masculine star at his most contradictory and dialogic. given that drag king performances parody both the contradictions of masculinity on stage, and the productive technologies of the star, king performances are essentially both meta-theatrical (performances about performing where lights, music, body language, dance all make the man) and meta-performativ ... | 2002 | 12769283 |
| seroprevalence of toxoplasma gondii infection among veterinary staff in ontario, canada (2002): implications for teratogenic risk. | toxoplasma gondii infection is embryotoxic in humans. it is mainly transmitted through raw/undercooked meat and ingestion of oocysts in cat feces. there remains controversy about the actual risk of cats transmitting the disease to humans. our primary objective was to determine the seroprevalence of t. gondii antibody among veterinary staff, to ascertain whether they have an increased risk through occupational exposure. our secondary objective was to examine their practices regarding cats, toxopl ... | 2003 | 12769831 |
| [another case of west nile fever in the netherlands: a man with encephalitis following a trip to canada]. | shortly after his return to the netherlands from a trip to ontario, a part of canada where infection with west-nile virus has been reported, a 69-year-old man became increasingly confused and generally unwell, accompanied by fever. the clinical picture was compatible with viral encephalitis and this was supported by eeg findings and the results of the cerebrospinal-fluid examination. mri of the brain did not contribute to the diagnosis. the patient was treated with aciclovir because herpes simpl ... | 2003 | 12784533 |
| investigating adverse outcomes in obstetrics. | investigation of adverse outcomes in health care requires a systematic and systemically oriented approach. this is true in obstetrics where, in western countries such as canada, adverse outcomes in the form of maternal mortality are rare. a model for such investigation is presented, based on answers to 3 questions: what? how? and why? these questions correspond to donabedian's 3 components of quality assurance: outcome, process, and structure, respectively. aspects of reason's model of accidents ... | 2003 | 12806452 |
| accuracy of trisomy 18 screening using the second-trimester triple test. | to assess the accuracy of the calculated risk for trisomy 18 assigned to individual women screened with the second-trimester triple test. | 2003 | 12813756 |
| isolation of candida dubliniensis in an aboriginal community in ontario, canada. | this study reports the first isolation of candida dubliniensis from north american indians. of 39 healthy human hosts sampled, two had c. dubliniensis. genotypic analysis identified polymorphisms in these strains and differences from two reference strains. our results suggest that yeast populations from indigenous communities in north america may be unique. | 2003 | 12843110 |
| the role of air pollution in the relationship between a heat stress index and human mortality in toronto. | in this study we considered confounding from air pollutants and chronological variables in the relation between humidex, a summer temperature and humidity index, and nonaccidental mortality, from 1980-1996 in toronto, canada. changes in the risk of death by age group, gender, and combined cardiac-respiratory cause of death were estimated for both 1 degree c and 50-95th percentile increases in humidex using a generalized additive linear model. with air pollution terms in the models, relative risk ... | 2003 | 12865043 |
| quadricuspid semilunar valves: report of two cases. | quadricuspid semilunar valves are uncommon congenital anomalies sometimes associated with severe valvular dysfunction. two cases of isolated quadricuspid semilunar valve were identified. the first, a heavily calcified quadricuspid aortic valve with four equal-sized cusps, was identified in a 56-year-old man at the time of valve replacement surgery for severe aortic stenosis and regurgitation. the second valve was a quadricuspid pulmonary valve with three equal-sized cusps and one smaller cusp, i ... | 2003 | 12876615 |
| effect of breastmilk consumption on neurodevelopmental outcomes at 6 and 12 months of age in vlbw infants. | to determine the influence of breastmilk consumption, as a dose response, in very low-birth-weight (vlbw) infants (< 1,500 g) on neurodevelopmental outcomes at 6 and 12 months corrected age, and to determine the influence of selected sociodemographic and infant variables on neurodevelopmental outcomes. | 2003 | 12881949 |
| prior opiate injection and incarceration history predict injection drug use among inmates. | to describe injection drug use among inmates, and to identify correlates of drug injection while incarcerated. | 2003 | 12930213 |
| isolation of enteric viruses in ontario during 1960-1962. | during the past three years at the central laboratory, ontario department of health, 681 isolations were made in tissue culture from 6822 specimens submitted for virus studies by physicians and hospitals from all over ontario. nearly 74% of the isolates were enteroviruses, approximately 5% adenoviruses and about 1% reoviruses. the remaining 20% are still to be identified.although the bulk of isolations was made during the same three-month period (august, september and october) of each year, the ... | 1963 | 14052975 |
| ionizing radiation as an industrial health problem. | ionizing radiation, first as x-rays, later in natural form, was discovered in europe in the late 1890's. immediate practical uses were found for these discoveries, particularly in medicine. unfortunately, because of the crude early equipment and ignorance of the harmful effects of radiation, many people were injured, some fatally. because of these experiences, committees and regulatory bodies were set up to study the problem. these have built up an impressive fund of knowledge useful in radiatio ... | 1964 | 14105012 |
| an outbreak of aseptic meningitis due to echo 25 virus. | in a widespread outbreak of aseptic meningitis during the summer and early fall of 1961 in ontario, echo type 25 virus was found to be the predominant virus type isolated from affected patients. recovery of echo 25 virus in several cases from the csf of patients strongly suggests an etiological relationship between this virus type and the illness. the causative role of the virus was confirmed by demonstration of significant immunological response in patients found to be infected with the virus. ... | 1964 | 14156829 |
| enteroviral and mumps meningitis in toronto, 1963. | virological investigations of 115 children with the aseptic meningitis syndrome during 1963 resulted in the isolation of enteroviruses from cerebrospinal fluid (csf) and/or feces of 21 of 48 children who had no association with mumps. for the third successive year, echo 9 was the dominant enterovirus in cases of aseptic meningitis in toronto children, but no rashes were associated with echo 9 meningitis during 1963, in contradistinction to previous years. mumps virus was isolated from csf of 25 ... | 1964 | 14158544 |
| q fever in canada. | a canada-wide survey of q fever was begun in 1958 in co-operation with public health and veterinary laboratories to determine the presence and prevalence of the disease so that medical practitioners might be alerted to the potential dangers existing. serologic evidence obtained indicated that the q fever rickettsia now exists in cattle in all provinces of canada except new brunswick, nova scotia, and prince edward island. isolations of the rickettsia were obtained from bovine milk samples from o ... | 1964 | 14175873 |
| epidemic type a influenza in southwestern ontario in 1963. | from february to april 1963 epidemic type a influenza occurred in southwestern ontario. eighty cases were diagnosed virologically, 24 of them by isolation of virus. the epidemic strain of virus proved unusually difficult to adapt to growth in embryonated eggs, and it had low avidity for antisera. antigenically it differed from a2 strains of earlier years and belonged to the subgroup of a2 influenza viruses characterized by the a2/japan/170/62 strain. antisera to a2 strains of earlier years neutr ... | 1964 | 14176060 |
| red cell glucose-6-phosphate dehydrogenase deficiency--a newly recognized cause of neonatal jaundice and kernicterus in canada. | seven male newborns of chinese, greek and italian origin presented with severe hemolytic jaundice due to red cell glucose-6-phosphate dehydrogenase (g-6-pd) deficiency. in five, the hemolysis was precipitated by inhalation of mothball vapours in the home. kernicterus was evident upon admission in six infants and was fatal in four of these.g-6-pd deficiency should be suspected as a cause of jaundice in all full-term male infants of these ethnic groups. the diagnosis can be confirmed in any hospit ... | 1964 | 14226101 |
| sporadic occurrence of echo virus types 27 and 31 associated with aseptic meningitis in ontario. | the sporadic occurrence of echo virus types 27 and 31 in association with aseptic meningitis during the enterovirus seasons in ontario in 1959 to 1962 is reported.the etiological significance of both of these isolates was verified by demonstration of type-specific serological response in meningitis patients. echo 27, which up to now has not been encountered in association with human illness, could be added to the list of viral agents capable of causing aseptic meningitis. isolation of echo 31 fr ... | 1964 | 14226105 |
| enteroviral syndromes in toronto, 1964. | virological or serological investigations of 72 children in toronto and environs, who were hospitalized between january and october 1964 with a variety of syndromes, revealed evidence of enteroviral infection in 29 subjects. coxsackie b2 was the dominant enterovirus, being isolated from feces and/or cerebrospinal fluid (csf) of three children with aseptic meningitis, three with pleurodynia, one with myalgia and one with pericarditis; four additional patients showed rising antibody titres to this ... | 1965 | 14269435 |
| impaired repression at a 5-hydroxytryptamine 1a receptor gene polymorphism associated with major depression and suicide. | inhibition of serotonergic raphe neurons is mediated by somatodendritic 5-ht1a autoreceptors, which may be increased in depressed patients. we report an association of the c(-1019)g 5-ht1a promoter polymorphism with major depression and suicide in separate cohorts. in depressed patients, the homozygous g(-1019) allele was enriched twofold versus controls (p = 0.0017 and 0.0006 for g/g genotype and g allele distribution, respectively), and in completed suicide cases the g(-1019) allele was enrich ... | 2003 | 14507979 |
| management of return-to-work programs for workers with musculoskeletal disorders: a qualitative study in three canadian provinces. | in this qualitative research project, researchers in three canadian provinces explored the perceptions of many different actors involved in return-to-work (rtw) programs for injured workers, studying their views on successful rtw strategies and barriers to/facilitators of the rtw process, then analyzing the underlying dynamics driving their different experiences. each research team recruited actors in a variety of different workplaces and key informants in the rtw system, and used a combination ... | 2003 | 14512241 |
| polyphenolic profiles in eight apple cultivars using high-performance liquid chromatography (hplc). | polyphenolic compounds of apple may play an important role in physiologic functions related to human health. different polyphenolics may have varied biological activities including antioxidant activity. the objective of this study was to investigate the profiles of polyphenolic compounds in different apple varieties and different parts of an apple. the total and individual polyphenolics differed significantly among the eight apple cultivars grown in ontario, and the peels had higher concentratio ... | 2003 | 14518966 |
| george fulford and victorian patent medicine men: quack mercenaries or smilesian entrepreneurs? | in the early twentieth century, a time when patent medicine men were stereotyped as evil and dishonest, g. t. fulford of brockville, ontario made his fortune from an iron pill called dr. williams' pink pills for pale people. once successful, fulford remained in brockville where he served on the town council and gave generously to charities. in 1900 he was appointed by laurier to the senate. when he died in 1905 he was remembered as a kind and ethical man. his story, like that of several other pr ... | 1999 | 14531402 |
| conservation of endangered species and the patterns and propensities of biodiversity. | it is commonly asserted in the ecological and economic literature that habitat loss is the main cause of loss of imperiled species. the evidence clearly shows that habitat loss is a common contributing factor, but there is little evidence that it is the most important factor. studies that have focused on the mechanisms of species loss have failed to produce models capable of predicting patterns of loss as a function of human activities. i propose that this is because ecologists have employed an ... | 2003 | 14558457 |
| maternal serum screening in ontario using the triple marker test. | to summarise the experience and evaluate the performance of the ontario maternal serum screening (mss) programme. | 2003 | 14561260 |
| how does fluoride concentration in the tooth affect apatite crystal size? | despite fluoride's (f) well-documented ability to prevent caries, the effects of f concentrations on enamel and dentin apatite crystals are unknown. the present study examined the hypothesis that tooth f concentration and tooth crystallite size correlate. one hundred human unerupted third molars were studied-53 from fortaleza-brazil (f water 0.7 ppm), 23 from toronto (1.0 ppm), and 24 from montreal (0.2 ppm). f concentration was analyzed by neutron activation analysis and apatite crystal size by ... | 2003 | 14578504 |
| beyond demographic change in human resources planning: an extended framework and application to nursing. | to introduce health care production functions into human resources planning and to apply the approach to analysing the need for registered nurses in ontario during a period of major reduction in inpatient capacity. | 2003 | 14596757 |
| northern initiative for social action: an occupation-based mental health program. | northern initiative for social action (nisa) is a consumer-run, occupation-based, nonprofit organization located in northeastern ontario, canada. the nisa organization has grown in response to research revealing few opportunities for participation in personally meaningful and socially valued occupation for persons with mental illness living in the community of study. this article describes a mixed-design research study conducted by the parnorth research unit of nisa and an occupational therapist ... | 2001 | 14601808 |
| current chemical exposures among ontario construction workers. | current occupational exposures to chemical agents were assessed as part of an epidemiological study pertaining to the cancer and mortality patterns of ontario construction workers. the task-based exposure assessment involved members from nine construction trade unions. air samples were taken using personal sampling pumps and collection media. a dusttrak direct-reading particulate monitor was also employed. exposure assessments included measurements of airborne respirable, inhalable, total, and s ... | 2003 | 14612300 |
| drive thru, prevent flu. | 2003 | 14638665 | |
| use of, effectiveness of, and attitudes regarding influenza vaccine among house staff. | to determine influenza vaccination rates, vaccine effectiveness, and factors influencing vaccination decisions among house staff. | 2003 | 14649772 |
| providing services globally: the experience of an internet pharmacy. | globalization of hospital-based medical services represents another step in the globalization of healthcare. the rise of transnational pharmaceutical firms represents an early example of the globalization of healthcare, which on the whole has provided many benefits. medical discoveries made in one country are rapidly and seamlessly made available to patients in other parts of the world. clinical research methodology has become much more sophisticated, and both the size and the scope of clinical ... | 2003 | 14660888 |
| diffuse panbronchiolitis in a caucasian man in canada. | diffuse panbronchiolitis (dpb) is a rare, chronic bronchiolar disease in non-asian populations and is therefore commonly overlooked in western countries. it usually affects nonsmokers and manifests as persistent air flow obstruction, chronic cough and interstitial nodular opacities. untreated, the prognosis is poor. in this report the authors describe a caucasian man of canadian descent who presented with progressive clinical and lung function impairment despite three years of bronchodilator and ... | 2003 | 14679410 |
| antidepressant medication use and breast cancer risk: a case-control study. | animal and human studies have reported an association between antidepressant (ad) medication use and breast cancer risk. a population-based case-control study was designed specifically to examine this association among women in ontario, canada. | 2003 | 14681256 |
| [historical archives of italian nephrology. diabetic nephropathy and insulin discovery: two parallel histories]. | in 1936, kimmelstiel and wilson described the nodular glomerulosclerosis in patients with diabetes mellitus on insulin treatment. the nodular glomerulosclerosis is referred to as diabetic nephropathy. fifteen years earlier insulin was discovered. this discovery at the university of toronto (canada) in 1921-22 by banting, macleod, best and collip was one of the most dramatic events in the history of the treatment of the disease. the impact of insulin was so sensational because of the incredible e ... | 2003 | 14732916 |
| canada: national summit on "global health is a human right"! | held in ottawa on 21-22 may 2003, a national summit on "global health is a human right!" brought together 86 people representing over 60 canadian civil society groups interested in joint advocacy on realizing the human right to health in developing countries. the summit focused particularly on addressing the global crises of communicable diseases such as hiv/aids, tuberculosis, and malaria. | 2003 | 14746307 |
| ontario commission criticizes insurance industry record on human rights. | 2002 | 14765494 | |
| ontario court recognizes constitutional equality rights of people "in receipt of social assistance". | on 13 may 2002, the ontario court of appeal released its unanimous decision in the falkiner case, which declared the definition of "spouse" in ontario's social assistance legislation to be unconstitutional because it discriminates on the basis of sex, marital status, and receipt of social assistance. the case is significant for people living with hiv/aids, given that a high proportion live on social assistance and thus face discrimination. | 2002 | 14765506 |
| responding to pandemic influenza: a local perspective. | to assess, via a tabletop exercise, the ability of a rural health unit to manage an influenza pandemic. | 2004 | 14768738 |
| noninvasive phenotypes of atherosclerosis: similar windows but different views. | noninvasive measures of atherosclerosis, such as carotid intima-media thickness, total carotid plaque area, and carotid stenosis, probably represent different phenotypes with distinct determinants. for instance, total carotid plaque area may reflect atherosclerotic lesion size more closely than carotid stenosis, which instead may reflect hemodynamic compromise within the arterial lumen. | 2004 | 14963285 |
| ontario appellate court denies hiv-positive man's constitutional claim to medical marijuana. | in january 2002, the ontario court of appeal denied a claim by a toronto man living with hiv/aids that canada's laws prohibiting marijuana possession and cultivation infringe his constitutional rights to liberty and security of the person. | 2002 | 14979265 |
| court orders publication ban in trial for identity of hiv-positive witness. | in september 2001, an ontario trial judge in a criminal assault case ordered a ban on publishing the identities of both the hiv-positive complainant and the man accused of assaulting the complainant, or any evidence from the legal proceedings that would tend to identify them. | 2002 | 14979269 |
| the changing costs of radiation treatment for early prostate cancer in ontario: a comparison between conventional and conformal external beam radiotherapy. | prostate cancer represents a large part of the workload for radiation oncology departments in canada. recent evidence suggests that conformal external beam radiotherapy improves results. the planning and treatment process for conformal patients requires a greater amount of resources that are in short supply in ontario. an understanding of these differences is important to provide an accurate estimate of future radiation needs of the province. these differences can be quantified in a cost model t ... | 2004 | 15003151 |
| the urban geography of sars: paradoxes and dilemmas in toronto's health care. | severe acute respiratory syndrome (sars) has impacted heavily on both canada's society and its health care system. quite unexpectedly, hospitals and health care workers became facilitators of disease diffusion. this experience has demonstrated the need for a comprehensive disease control strategy. | 2004 | 15012634 |
| radiation treatment of lung cancer--patterns of practice in canada. | to assess the patterns of practice among canadian radiation oncologists who treat lung cancers. | 2004 | 15110450 |
| gastrointestinal bleeding after the introduction of cox 2 inhibitors: ecological study. | 2004 | 15138157 | |
| criteria to assess and select sites for long-term avian monitoring in an urbanizing landscape. | a methodology was developed to prioritize the suitability of sites for long-term monitoring of avian populations, including vulnerable species, both to enhance assessment of changes in ecological resources and to facilitate land-use planning at the regional scale. this paper argues that a successful monitoring program begins with a site prioritization procedure that integrates scores based on spatial controls with ecological and socio-economic indicators, particularly those dependent on communit ... | 2004 | 15141452 |
| analysis of the novel tph2 gene in bipolar disorder and suicidality. | 2004 | 15197398 | |
| neurological manifestations of west nile virus infection. | over the past four years, west nile virus (wnv) has become a significant health issue in north america. in 2002, wnv infection made its first appearance in the human population in canada. | 2004 | 15198442 |
| association between schizophrenia and the syntaxin 1a gene. | both microarray and candidate molecule studies have demonstrated that protein and mrna expression of syntaxin and other genes involved in synaptic function are altered in the cerebral cortex of patients with schizophrenia. | 2004 | 15219469 |
| community influenza outbreaks and emergency department ambulance diversion. | influenza has been linked to emergency department (ed) crowding, yet few studies have examined this association. we describe the relationship between ed crowding and influenza outbreaks. | 2004 | 15226710 |
| current man-made mineral fibers (mmmf) exposures among ontario construction workers. | current occupational exposures to man-made mineral fibers (mmmf), including refractory ceramic fibers (rcf), were measured as part of an exposure assessment program for an epidemiological study pertaining to cancer and mortality patterns of ontario construction workers. the assessments were carried out at commercial and residential sites. a total of 130 mmmf samples (104 personal and 26 area) was collected and included 21 rcf (16 personal and 5 area). the samples were analyzed by the world healt ... | 2004 | 15238339 |
| effectiveness of inactivated trivalent influenza vaccine in long-term care institutions, toronto, 2003-2004. | 2004 | 15239482 | |
| an advisory committee statement (acs). national advisory committee on immunization (naci). statement on influenza vaccination for the 2004-2005 season. | 2004 | 15239483 | |
| gender and income in pharmacy: human capital and gender stratification theories revisited. | this is a case study of gender and earnings in pharmacy--a profession characterized by its rapid recruitment of female practitioners. we try to account for disparities in earnings between male and female pharmacists in ontario with the aid of human capital theory and gender stratification theory. data is drawn from a random sample of 463 ontario pharmacists. we find a consistent sex gap in earnings regardless of occupational level of practitioners (i.e. owner, manager or employee) and net of suc ... | 1999 | 15266676 |
| pulmonary pathology of severe acute respiratory syndrome in toronto. | the severe acute respiratory syndrome (sars) pandemic in toronto resulted in a large number of autopsies on its victims. we describe the pulmonary pathology of patients who died in the 2003 toronto outbreak. autopsy material from the lungs of 20 patients who died between march and july 2003 were characterized by histology, molecular biology, and immunohistochemistry for cytokeratins, thyroid transcription factor-1, cd68, epstein-barr virus, cytomegalovirus, and human herpes simplex viruses. matc ... | 2005 | 15272286 |
| rates of influenza vaccination in older adults and factors associated with vaccine use: a secondary analysis of the canadian study of health and aging. | influenza vaccination has been shown to reduce morbidity and mortality in the older adult population. in canada, vaccination rates remain suboptimal. we identified factors predictive of influenza vaccination, in order to determine which segments of the older adult population might be targeted to increase coverage in influenza vaccination programs. | 2004 | 15306030 |
| isolation of methicillin-resistant staphylococcus aureus from the environment in a veterinary teaching hospital. | after recognition of a cluster of methicillin-resistant staphylococcus aureus (mrsa) infection in horses and humans at the ontario veterinary college veterinary teaching hospital, environmental contamination with mrsa was evaluated. a total of 260 environmental surfaces were sampled during periods when mrsa-infected horses were hospitalized, and mrsa was isolated from 25/260 sites (9.6%). the most commonly contaminated sites were stalls housing mrsa-positive horses, but other stalls, medical equ ... | 2004 | 15320581 |
| family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hmsh2 or hmlh1. | hereditary non-polyposis colorectal cancer (hnpcc) results from inactivating germline mutations in a set of dna-mismatch-repair genes, of which the most clinically relevant are hmsh2 and hmlh1. computer-assisted pedigree risk assessment tools are available to assist in the calculation of an individual's likelihood of bearing such a deleterious mutation. one such tool, cancergene version 3.4 (http://www3.utsouthwestern.edu/cancergene) was used to assess the risk of a deleterious mutation in the g ... | 2004 | 15324316 |
| antidepressant medication use and non-hodgkin's lymphoma risk: no association. | animal and human studies have suggested that antidepressant medications may be associated with several cancers. the authors evaluated the association between antidepressant medication use and the risk of non-hodgkin's lymphoma using a canadian population-based case-control study, the national enhanced cancer surveillance study. non-hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the ontario cancer registry, and controls (n=1,930) were identified from the ontario min ... | 2004 | 15353417 |
| effect of 4-aminopyridine on gait in ambulatory spinal cord injuries: a double-blind, placebo-controlled, crossover trial. | animal and human research have shown that the drug 4-aminopyridine (4-ap) may improve gait in spinal cord lesions by enhancing nerve transmission to affected muscles. | 2004 | 15356676 |
| the baycrest sars experience: the human side. | toronto, in the province of ontario, canada was one of the cities severely impacted by severe acute respiratory syndrome (sars). sars required the health care system to respond quickly and efficiently. this paper describes the situation and response at a large public academic aged care centre. | 2003 | 15368814 |
| development and assessment of the canadian personal load carriage system using objective biomechanical measures. | the defence research and development canada--toronto managed a collaborative team of designers, biomechanists, ergonomists and military stakeholders in the development of a new personal load carriage (lc) system for the canadian forces. ergonomics design principles using objective measurement tools and user-centred feedback from soldiers were considered essential to system development. the purpose of this study was to provide a detailed report of contributions by biomechanical testing to the fin ... | 2004 | 15370846 |
| a suite of objective biomechanical measurement tools for personal load carriage system assessment. | for application to military and civilian needs, defence research and development canada--toronto contracted queen's university, kingston to develop a suite of biomechanical assessment and analytical tools to supplement human-based load carriage system assessment methods. this suite of tools permitted efficient objective evaluation of biomechanical aspects of load-bearing webbing, vests, packs and their components, and therefore contributed to early system assessment and a rapid iterative design ... | 2004 | 15370854 |
| growing older: the lived experience of older persons with serious mental illness. | the purpose of this qualitative paper is to describe, from the consumers' perspective, the complex factors involved as persons with serious mental illness grow older in the community. the results consisted of seven major themes subsumed under three categories. the first category, across the lifespan, included three themes: (a) older but wiser, (b) one day at a time, and (c) echoes from the past. the second category, factors impeding participation in the life of the community, also included three ... | 2003 | 15462578 |
| consensus-seeking roundtable on placebos in clinical research. | 1998 | 15468464 | |
| presentation to the standing committee on health, ottawa, december 7, 1999. | 2000 | 15468469 | |
| levels of citation of nonhuman animal studies conducted at a canadian research hospital. | the publication of scientific articles that receive few or no citations raises questions of the appropriate use of resources as well as ethics. in the case of animal research, the ethics issue extends beyond human patients to nonhuman animals, as the research subjects them to pain and, typically, to death. this study is a citation analysis of animal research conducted at toronto's hospital for sick children (hsc). of the 594 publications (1990 to 1995) on animal research by affiliates of hsc, 29 ... | 2004 | 15498728 |
| association between biallelic and monoallelic germline myh gene mutations and colorectal cancer risk. | the muty human homologue (myh) gene encodes a member of the base excision repair pathway that is involved in repairing oxidative damage to dna. two germline myh gene mutations that result in myh proteins containing amino acid substitutions y165c and g382d (hereafter called the y165c and g382d mutations) are associated with adenomatous poly-posis and colorectal cancer among patients from several european poly-posis registries. we used a population-based series of 1238 colorectal cancer patients a ... | 2004 | 15523092 |
| obesity research in canada: literature overview of the last 3 decades. | to identify research published on obesity in canada, to explore the range of areas studied, and to identify gaps and areas that merit future research attention. | 2004 | 15536218 |
| minimal risk and its implications. proceedings of the ncehr national workshop on minimal risk, march 31-april 1, 2000 held in ottawa, ontario, canada. | 2001 | 15540386 | |
| passive sampling survey of polybrominated diphenyl ether flame retardants in indoor and outdoor air in ottawa, canada: implications for sources and exposure. | the polybrominated diphenyl ethers (pbdes) are widely used as flame retardants in plastics of soft furnishings, tv sets and computers, and insulation in the indoor environment. the penta-bdes--now banned in most parts of europe but still used in north america--are additive flame retardants that may be released to the indoor environment via volatilization or as dusts. in this study, to investigate general population pbde exposure, air was sampled in 74 randomly selected homes in ottawa, canada an ... | 2004 | 15543731 |
| perfluoroalkyl contaminants in a food web from lake ontario. | perfluorooctane sulfonate (pfos) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlife worldwide that has alerted scientists to examine the environmental fate of other fluorinated organic contaminants. recently a homologous series of perfluoroalkyl carboxylates (pfcas) was detected in the arctic, yet little is known about their sources, breadth of contamination, or environmental distribution. in this study we analyzed for pfos, the homologous series of pfcas r ... | 2004 | 15543740 |
| report of the 2003 pan-canadian forum on cervical cancer prevention and control. | to develop evidence-based consensus recommendations on the delivery of cervical cancer screening, human papillomavirus (hpv) education, hpv testing, and the optimal tool for cervical cytology within the canadian health system. | 2004 | 15560864 |
| stem cell research and transplantation: science leading ethics. | one of the most exciting developments in the biological sciences in the past decade has been the discovery and characterization of human embryonic stem cells (escs). the interest to transplanters is the potential applications of stem cells in regenerative medicine (rm), which may involve tissue engineering, genetic engineering, and other techniques to repair, replace, or regenerate failing tissues and organs. there is little controversy surrounding human adult stem cells. however, human escs are ... | 2004 | 15561296 |
| blurring the boundaries of space: shaping nursing lives at the red cross outposts in ontario, 1922-1945. | historians and other scholars interested in the history of hospitals have investigated the links between medical architecture and the organization of space with the evolution of modern medicine. the transformation over time in the architectural for of medical institutions has tended to reflect developments in medical science and therapeutic efficiency as well as elements in the broader social climate. some authors, however, have argued for the agency of structure and spatial organization, to con ... | 2004 | 15568264 |
| outpatient chemotherapy administration: decreasing wait times for patients and families. | increasingly, there is a trend to deliver chemotherapy, where possible, in the outpatient ambulatory setting. in the few studies that have explored the setting of cancer care, long wait times are frequently linked to dissatisfaction. several factors contribute to lengthy waiting times for patients and their families: long registration processes, lag times associated with obtaining laboratory results, time required for patient assessments and preparation of chemotherapeutic agents, adequacy of nu ... | 2005 | 15574724 |
| site-specific cytosine methylation in s-comt promoter in 31 brain regions with implications for studies involving schizophrenia. | the catechol-o-methyltransferase (comt) gene on chromosome 22q11 has been considered a strong candidate gene for schizophrenia (sz) susceptibility. a functional val/met polymorphism in exon 4, with potential to affect comt activity has been implicated in sz, but the results remain inconclusive. we hypothesized that the association of comt gene with sz is not strictly a genetic alteration but could involve dna methylation, as an epigenetic alteration. thus, we chose to examine the cytosine dna me ... | 2005 | 15635661 |
| influenza and pneumonia hospitalizations in ontario: a time-series analysis. | a comprehensive examination of gender and age-specific influenza and pneumonia hospitalization seasonality is currently lacking. using population-based data for ontario, canada between april 1988 and march 2002 (n = 339,803 hospitalizations), findings from this study revealed clear seasonality [fisher's kappa (fk) test = 68.64, p < 0.001; bartlett's kolmogorov-smirnov (bks) test = 0.68, p < 0.001] with consistent summer troughs and winter peaks for both sexes and all ages combined. the very youn ... | 2004 | 15635976 |
| work-related disability in canadian nurses. | to determine factors contributing to high registered nurse (rn) injury claim rates in canadian hospitals. | 2004 | 15636416 |
| setting up a mobile dental practice within your present office structure. | different service models have emerged in canada and the united states to address the issue of senior citizens' lack of access to comprehensive dental care. over the past decade, one such model, the use of mobile dental service units, has emerged as a practical strategy. this article describes a mobile unit, operated as an adjunct to the general practitioner's office and relying mainly on existing office resources, both human and capital, to deliver services at long-term care institutions. the es ... | 2005 | 15691425 |
| beliefs and practices of ontario midwives about influenza immunization. | with an increasing number of births in ontario being conducted by midwives, we undertook a survey of the beliefs and practices of 256 licensed ontario midwives and student midwives about immunization, particularly against influenza. overall, 42.9% (48/112) of midwives considered that they knew a lot about immunization; however, 36.2% (38/105) reported no education about immunization during their training. a small majority (55.9%) were in favour of vaccination in general and only 2 of 113 reporte ... | 2005 | 15694509 |
| association of seek1 and psoriatic arthritis in two distinct canadian populations. | to examine the relationship between snp +39604 in seek1 and psoriatic arthritis (psa) in two distinct canadian populations. | 2005 | 15708881 |
| disability management practices in education, hotel/motel, and health care workplaces. | the high costs and the impact of work disability have become a growing concern for workplaces. as a result, workplace disability management approaches have been developed to lower disability costs, protect the employability of workers, and promote early return to work. | 2005 | 15712255 |
| reunification of child and animal welfare agencies: cross-reporting of abuse in wellington county, ontario. | institutional change has resulted in the separation of organizations for the protection of animals and children. this project reunites two organizations to examine associations between human violence and animal cruelty. for 12 months, family and children's services (fcs) investigators and humane society (hs) investigators in wellington county, canada, completed checklists to examine connections between forms of violence. fcs workers found some cause for concern in 20% of 1,485 homes with an anim ... | 2005 | 15717773 |