Publications

antiprotease targeting: altered specificity of alpha 1-antitrypsin by amino acid replacement at the reactive centre.	alpha-1 antitrypsin (alpha 1at) is an efficient inhibitor of the human neutrophil proteases, elastase and cathepsin g. the reactive centre p1 residue (met358) of alpha 1at is important in defining the specificity of inhibition; furthermore, oxidation of this residue results in a loss of inhibitor activity. there is evidence that oxidative inactivation of alpha 1at may be involved in the pathogenesis of pulmonary emphysema associated with cigarette smoking. we have studied the effect of a series ...	1986	3544150
another animal escherichia coli cytopathic factor.		1986	3544462
lung mechanics with relation to pulmonary haemodynamics, gas exchange and extravascular lung water in mechanically ventilated endotoxaemic pigs.	in a porcine model employing a continuous i.v. infusion of e. coli endotoxin the pathophysiology of early adult respiratory distress syndrome was studied with main emphasis on the early changes in lung mechanics and their relation to changes in pulmonary haemodynamics, gas exchange and extravascular lung water in intermittent positive pressure ventilated (ippv) pigs under ketamine anaesthesia. six animals served as controls and revealed no major physiological changes. nine animals received endot ...	1986	3544623
photobiological activity of certain pyranocoumarin derivatives: potential agents for the photochemotherapy of psoriasis.	the photobiological properties of a series of pyranocoumarin derivatives having linear (xanthyletines) and angular structure (seselins) have been studied; while the linear derivative carrying the methyl geminal group, typical of the parent natural compound, appeared to be entirely inactive in all tests performed, very probably because of the steric hindrance in the dark interaction with dna, 4 substances lacking in this group showed a marked capacity for inhibiting dna synthesis in ehrlich cells ...	1986	3547353
[phospholipase a from the pancreas and e. coli].		1986	3547505
bacterial populations on dressed pig carcasses.	samples were collected at two abattoirs from four sites on pig carcasses as they were being placed in a chiller. bacteriological examination showed that no single sampling site could be used to assess the microbiological status of pig carcass surfaces. sampling from multiple sites on a carcass may be required to assess the degree of contamination by different bacteria. it is suggested that the hygiene of slaughtering and dressing of pig carcasses at an abattoir cannot be assessed on a single vis ...	1987	3549337
spacer alterations which increase the expression of porcine growth hormone in e. coli.	full-length porcine growth hormone (pgh) cdna clones were isolated from a porcine pituitary cdna library. when the coding portion of the pgh gene was cloned into an e. coli expression vector downstream from the powerful trc promoter, high levels of mrna, but no protein were detected. mutation directed by an oligodeoxynucleotide primer altered 5'-non-coding sequences and raised the level of pgh produced from undetectable to 15% of the total cellular protein. alteration of four codons infrequently ...	1987	3549357
influence of the hal locus and standardized stress on antibody response and in vitro reactivity of peripheral blood lymphocytes in pigs.	the antibody response to two escherichia coli antigens (o149 and k88) and the in vitro reactivity of peripheral blood lymphocytes (pbls) to pokeweed mitogen was studied in growing pigs after exposure to varying degrees of stress. three experimental groups were used; transportation by lorry, transportation by lorry after a previous injection of a tranquillizing drug (amperozide), no transportation but an amperozide injection. another group was used as a control group. this group was not transport ...	1987	3564363
association of enterotoxigenic bacteroides fragilis with diarrheal disease in young pigs.	enterotoxigenic bacteroides fragilis (etbf) was isolated from intestinal contents of 10 of 45 pigs with diarrhea. of 10 etbf-positive pigs, seven were 1 to 4 weeks of age, whereas three pigs had diarrhea after weaning (6 to 8 weeks of age). of ten pigs infected with etbf, nine were also infected with k88-positive escherichia coli, rotavirus, coronavirus, coccidia, or cryptosporidium. of 11 conventional pigs exposed to etbf at 1 to 2 days of age, two subsequently developed fatal postweaning diarr ...	1987	3592377
cloning and sequence analysis of mrna for mouse aspartate aminotransferase isoenzymes.	the nucleotide sequences of mrnas for the mouse mitochondrial and cytosolic aspartate aminotransferase isoenzymes (maspat and caspat) (ec 2.6.1.1) were determined from complementary dnas. the maspat mrna comprises minimally 2460 nucleotides and codes for a polypeptide of 430 amino acid residues corresponding to the precursor form of the maspat (pre-maspat). the caspat mrna comprises minimally 2086 nucleotides and codes for a polypeptide of 413 amino acid residues. the region coding for the matur ...	1986	3782150
experimental porcine eperythrozoonosis: t-lymphocyte suppression and misdirected immune responses.	immune responses and hematologic alterations were investigated in splenectomized pigs after im inoculation with eperythrozoon suis. early hematologic alterations were massive parasitism of rbc, severe hypoglycemia, moderate bilirubinemia, and mild anemia; later findings included severe anemia, minimal parasitism of rbc, spontaneous agglutination of rbc at 25 c and 4 c which was reversible at 37 c, transient thrombocytopenia, and mild bilirubinemia. the humoral immune responses consisting of a tr ...	1985	3874572
reaction of substrates with 35s-thiophosphorylated succinyl-coa synthetase of pig heart. similarities to the case of the escherichia coli enzyme.	guanosine 5'-o-(3-thio)triphosphate (gtp gamma s) was found to be a substrate of pig heart succinyl-coa synthetase with km and kcat values of 3 microm and 0.23 s-1, respectively. the corresponding values with gtp as substrate were 48 microm and 65 s-1. 35s-thiophosphorylated enzyme was prepared by incubation of pig heart succinyl-coa synthetase with [35s]gtp gamma s. a comparison was made of thiophosphoryl group release by substrates from this alpha beta (one active site) enzyme with that of the ...	1985	3882686
channeling of a beta-oxidation intermediate on the large subunit of the fatty acid oxidation complex from escherichia coli.	the kinetic properties of the fatty acid oxidation complex from escherichia coli were studied with the aim of elucidating the functional consequence of having enoyl-coa hydratase and 3-hydroxyacyl-coa dehydrogenase associated with a multifunctional polypeptide. the kinetic parameters of individual enzymes were determined and used in model calculations based on a published theory (storer, a. c., and cornish-bowden, a. (1974) biochem. j. 141, 205-209) to predict the kinetic behavior of a system of ...	1985	3882701
resistance of gnotobiotic large white and chinese piglets to in vivo attachment of a k88ab enterotoxigenic escherichia coli strain.	in vivo adhesion of a k88ab-positive enterotoxigenic escherichia coli (etec) strain to the small intestinal wall of gnotobiotic, colostrum-deprived chinese and large white piglets was investigated. a non-enterotoxigenic, attachment factor-deprived e. coli strain, inoculated in association with the k88ab etec strain, was used as a marker to determine the content residues on the intestinal walls of gnotobiotic piglets. both strains were selectively numerated in the luminal contents and on the wash ...	1985	3883453
naturally occurring plasmid coding for heat-labile enterotoxin production and drug resistance from escherichia coli strain of porcine origin.		1985	3884865
evaluation of procholeragenoid against experimental colibacillosis in piglets of vaccinated dams.	a toxoid prepared from the toxin of vibrio cholera was adjuvanted with aluminium hydroxide and used for immunisation of pregnant gilts. litters of these and of non-vaccinates were experimentally challenged with escherichia coli producing either heat labile and heat stable (lt and st) enterotoxins or st enterotoxin only. both the challenge strains of e coli produced high rates of mortality (64 and 68 per cent) and morbidity (80 and 100 per cent) in litters of non-vaccinated dams. statistically hi ...	1985	3885554
haemagglutinins & enterotoxins in escherichia coli strains from human urinary tract infections.		1985	3886540
linkage of genes for heat-stable enterotoxin, drug resistance, k99 antigen, and colicin in bovine and porcine strains of enterotoxigenic escherichia coli.	linkages among genes for production of escherichia coli heat-stable enterotoxin (st), drug resistance, k99 antigen, and colicin were investigated in 2 bovine and 3 porcine strains of enterotoxigenic e coli. in conjugation experiments, all 5 isolates transferred enterotoxigenicity and the ability to produce k99; 4 of the 5 isolates also transferred antibiotic resistance markers, and 3 colicinogenic strains transmitted the ability to produce colicin. in 2 of the 3 colicin-producing strains, the ge ...	1985	3888010
effect of intravenous and intraduodenal administration of escherichia coli endotoxin on the porcine pancreas as evaluated by changes in the serum cationic trypsin-like immunoreactivity.	in six pigs intravenous administration of escherichia coli endotoxin caused septic shock and a significant increase in serum cationic trypsin-like immunoreactivity (ctli), with activation of cationic trypsinogen to trypsin and formation of complexes between cationic trypsin, on the one hand, and alpha 2-macroglobulin and alpha 1-antitrypsin, on the other, compatible with acute pancreatitis. in contrast, intraduodenal infusion of e. coli endotoxin to seven other pigs was without effect on the gen ...	1985	3890137
the effects of oxytetracycline on the intestinal escherichia coli flora of newly weaned pigs.	four recently weaned pigs were dosed orally with oxytetracycline. this caused a rapid increase in the incidence of tetracycline resistance (tcr) among escherichia coli isolates from the faecal flora. the isolates were differentiated further on the basis of o-serogroup, biotype and resistance pattern. there was no evidence that the administration of the antibiotic selected for a few tcr clones, but rather a relatively large number of tcr strains were identified during the dosing period. using sel ...	1985	3894511
in vivo escherichia coli k88 adhesion in gnotobiotic piglets: comparison between large white and chinese piglets.		1985	3895235
effects of escherichia coli heat-stable enterotoxin, atropine, clonidine, and morphine on chloride efflux from isolated enterocytes.	the effects of escherichia coli heat-stable enterotoxin (st) on chloride efflux rate were investigated in 3 fractions of enterocytes isolated in a villus-to-crypt gradient from porcine jejunum. there was no difference in chloride efflux rates between mature and immature cells from controls. heat-stable enterotoxin significantly increased chloride efflux in all fractions. morphine inhibited st-augmented secretion in mature enterocytes. atropine or clonidine had no effect. calcium efflux rates and ...	1985	3904545
acquisition of genes from an o18:k1:h7 colv+ strain of escherichia coli renders intracranially-inoculated e. coli k12 highly virulent for chickens, ducks and guinea-pigs but not mice.	the virulence of intracranially-inoculated mutant forms of an o18ac:k1:h7 colv+ strain of escherichia coli (designated mw) that lacked different combinations of its o and k antigens and colv, and of an e. coli k12 strain to which these characters had been transmitted was studied in mice, chickens, ducks and guinea-pigs. the o18+k1+colv+ form of mw was highly virulent for chickens and mice but the corresponding form of k12 was only highly virulent for chickens; the o18-k1-colv- forms of both stra ...	1985	3905956
a porcine model of early adult respiratory distress syndrome induced by endotoxaemia.	to study the pathophysiology of early adult respiratory distress syndrome (ards) induced by sepsis, spontaneously breathing pigs under ketamine anaesthesia were investigated. twenty animals were infused i.v. with e. coli endotoxin (10 micrograms . h-1 . kg-1) over 6 h, and ten control animals received physiological saline. in the controls, cardiac output (qt) and o2 delivery decreased slightly. there were no changes in pulmonary gas exchange, pulmonary haemodynamics or extravascular lung water ( ...	1985	3909709
in vivo aspects of urogastrone-epidermal growth factor.	recent evidence indicates that human urogastrone-epidermal growth factor originates in submandibular and brunner's glands and that serum levels are low (less than 1 ng ml-1). it occurs in many secreted fluids to a much greater extent and many tissues are thus exposed to concentrations greater than 100 ng ml-1. rapid actions in vivo of uro-egf include the ability to inhibit gastric acid secretion at low doses (250 ng kg h-1 in humans) and to provide cytoprotective effects against ulcerogenic agen ...	1985	3914989
the study of fecal-escherichia coli peritonitis-induced septic shock in a neonatal pig model.	peritonitis-induced septic shock in the neonate is associated with a high mortality. because there exists no clinically relevant model to study resuscitation of these patients, a model using the neonatal pig was developed. after arterial and central venous cannulation, and placement of a left pulmonary-artery thermodilution catheter, 12 anesthetized neonatal pigs were "resuscitated" with fluids (5% albumin in lactated ringer's solution at 15 ml/kg/hr), antibiotics, and correction of acidemia. th ...	1985	3915235
the role of intramembrane ca2+ in the hydrolysis of the phospholipids of escherichia coli by ca2+-dependent phospholipases.	ca2+-dependent phospholipases a require ca2+ concentrations in the millimolar range for optimal activity toward artificial substrates. because ca2+-dependent phospholipases a2 degrade the phospholipids of escherichia coli, treated with the membrane-active antibiotic polymixin b equally well with and without added ca2+ (weiss, j., beckerdite-quagliata, s., and elsbach, p. (1979) j. biol. chem. 254, 11010-11014), we have examined the possibility that intramembrane ca2+ can provide the ca2+ needed ...	1985	3918043
analysis of receptor-binding site in escherichia coli enterotoxin.	heat-labile enterotoxin produced by enterotoxigenic escherichia coli and cholera enterotoxin are both composed of a and b subunits. the a subunit is an enzymatically active adp-ribosylating subunit, while the b subunit, consisting of 103 amino acids, binds the toxin to a receptor, gm1-ganglioside, on the cell surface. a mutant isolated after treatment of e. coli producing heat-labile enterotoxin with n-methyl-n'-nitro-n-nitrosoguanidine produces a b subunit that is unable to bind to ganglioside. ...	1985	3924916
insulin-related material in microbes: similarities and differences from mammalian insulins.	we have reported that extracts of escherichia coli and tetrahymena grown in synthetic media contained material that reacted specifically in the immunoassay and bioassay for insulin. one additional strain of tetrahymena and four of e. coli yielded amounts of material similar to those reported previously. in addition to their behavior on sephadex g-50, the immunoactive insulin-related materials from the microbial sources behaved like authentic vertebrate insulins in their ability to be adsorbed to ...	1985	3933801
beta-sulfur substituted alpha-ketoglutarates as inhibitors and alternate substrates for isocitrate dehydrogenases and certain other enzymes.	the rs-isomers of beta-mercapto-alpha-ketoglutarate, beta-methylmercapto-alpha-ketoglutarate and beta-methylmercapto-alpha-hydroxyglutarate have been synthesized. beta-mercapto-alpha-ketoglutarate was a potent inhibitor, competitive with isocitrate and noncompetitive with nadp+, of the mitochondrial nadp-specific isozyme from pig heart (ki = 5 nm; km (dl-isocitrate)/ki(rs-beta-mercapto-alpha-ketoglutarate) = 650) and pig liver, the cytosolic isozyme from pig liver (i0.5 = 23 nm), and the nadp-li ...	1986	3947094
immunopharmacological activities of a synthetic counterpart of a biosynthetic lipid a precursor molecule and of its analogs.	synthetic lipid a analogs (compounds 404 through 406) were examined for their immunopharmacological activities. these compounds had two amide-bound and two ester-bound (r)-3-hydroxytetradecanoyl groups at the c-2 and c-2' and the c-3 and c-3' positions, respectively, of beta (1-3)glucosamine disaccharide. in all of the in vitro assays, these synthetic compounds exhibited high activities comparable to those of a reference lipid a prepared from escherichia coli o8:k27 re-mutant strain f515. the co ...	1985	3980084
effect of lidamidine-hcl on escherichia coli heat-stable enterotoxin-induced jejunal water and electrolyte secretion in neonatal piglets.	neonatal piglets were anesthetized, and two jejunal loops, 20 cm in length, were prepared. then, either water or 0.12, 0.25, 0.5 or 1.0 mg/kg of lidamidine-hcl was injected intraduodenally on a randomized basis, one treatment per pig. following this, a crude heat-stable enterotoxin (st) preparation produced from e. coli no. 1261 was injected into the proximal jejunal loop, and trypticase soy broth (tsb) (with osmolality adjusted to equal the enterotoxin preparation) was injected into the distal ...	1985	4020946
enteropathogenic escherichia coli on the intestinal mucopolysaccharide layer of pigs.		1971	4106779
a technique for ultracryotomy of cell suspensions and tissues.	ultracryotomy of fixed tissue has been investigated for a number of years but, so far, success has been limited for several reasons. the simple technique herein reported allows the ultracryotomy not only of a variety of tissues but also of single cells in suspension, with a preservation and visualization of ultrastructural detail at least equivalent to that obtained with conventional embedding procedures. in this technique, sucrose is infused into glutaraldehyde-fixed tissue pieces before freezi ...	1973	4121290
[penicillin allergy: physico-chemical and biological properties of macromolecular impurities].		1972	4121820
lymphocyte-derived eosinophil chemotactic factor. ii. studies on the mechanism of activation of the precursor substance by immune complexes.		1973	4126774
immunity to escherichia coli in pigs: igg and blood clearance.		1974	4133893
[comparative studies on the pathology and pathogenesis of spontaneous coli enterotoxemia and of the experimental coli endotoxin syndrome in swine. v. studies on the pathomorphology of the central nervous system in spontaneous coli enterotoxemia and the experimental coli endotoxin syndrome].		1974	4136319
the use of germ-free piglets in the study of lymphoid tissue and germinal centre formation.		1973	4137308
[transmission and inhibition of extrachromosomal drug-resistance factors in the gastrointestinal flora].		1972	4145555
on the effect of temperature on the absorption spectra of free and protein-bound flavines.		1973	4149349
[incidence of colicinogenic e. coli in the gut flora of healthy pigs (author's transl)].		1973	4150076
[the effects of human-and animal-pathogenic coli strains on the isolated intestine of rabbit (author's transl)].		1974	4151208
transferable tetracycline resistance in salmonella cholerae-suis var. kunzendorf.		1974	4155891
infectious drug resistance in escherichia coli isolated from healthy farm animals.		1966	4163427
[treatment of diarrhea in piglets with porcine gamma globulins].		1970	4191589
effects of escherichia coli on germ-free and gnotobiotic pigs. ii. serum proteins and antibodies.		1970	4194797
[intraepithelial multiplication of enterobacteriaceae and its role in the pathogenesis of dysentery and intestinal coli-infection].		1973	4197099
iga immunoglobulin levels in porcine sera and mammary secretions.		1973	4204992
peptic digestion of pig igm.		1974	4208583
[adjuvant activity of monomeric fractions of bacterial peptidoglycans in delayed hypersensitivity].		1974	4211288
an attempt to experimentally produce edema disease in swine by oral administration of escherichia coli serotype o139:k82:h1.	diarrhea, reduced appetite, and nervousness were observed following oral exposure of six pigs to freeze-thaw extract and living culture of e. coli strain 0139:k82:h1. the most significance gross change was the appearance of subserosal edema of the mesentry, especially of the mesocolon. histological findings included perivascular edema of the brain and reticulum cells as well as lymphocytic aggregates in the renal cortex simulating early neoplasia. edema of the submucosa of gallbladder, the duode ...	1969	4237301
[r factors in strains of pathogenic enterobacteria isolated from domestic animals and particularly from dogs].	strains of enterobacteria (nine escherichia coli and two salmonella) isolated from primary or secondary infections in the dog, cat, pig, calf and kangaroo were studied for the presence of extrachromosomal drug resistance factors (r factors). seven strains of e. coli and two strains of salmonella transferred resistance involving the following antibiotics: streptomycin, ampicillin, chloramphenicol, neomycin and tetracycline. all strains harboring r factors transferred streptomycin resistance and t ...	1972	4258542
ecology of intestinal escherichia coli in pigs.	the coliflora of three groups of young pigs was shown to be dominated by a small number of escherichia coli types, as determined by their o antigen, that maintained a tenure of several days or weeks. the pattern of successive waves of e. coli was similar in littermates but, in general, each pig harboured a unique sequence of e. coli types. the e. coli flora from a litter was also shown to be dominated by a small number of e. coli types whose tenure averaged several weeks. a limited amount of inf ...	1971	4260947
a comparative study of the rabbit and pig gut loop systems for the assay of escherichia coli enterotoxin.	a comparison was made between segments of pig and rabbit small intestine in their response to heat-labile (lt) and heat-stable (st) preparations from porcine enteropathogenic escherichia coli. either whole cell lysates or dialysed broth culture supernatants were used as sources of lt and soft agar culture fluids as a source of st. whole cell lysates of all thirteen lt-producing e. coli strains tested regularly elicited fluid accumulation in rabbit gut loops. whole cell lysates of certain e. coli ...	1972	4263909
experimental colibacillosis in gnotobiotic body pigs. ii. pathology.	sixty-two neonatal gnotobiotic pigs were used in three experiments to determine the lesions produced by two closely related strains of escherichia coli o138:k81:nm (of michigan origin) and o138:k81 (of minnesota origin). exposure was by subcutaneous injection of bacterial culture into the umbilical stump or by oral inoculation. gross signs common to monocontaminated pigs included distention of the flaccid small and large intestines with fluid contents. edema was prominent in various tissues of m ...	1973	4270434
experimental edema disease of swine (e. coli enterotoxemia). i. dectection and preparation of an active principle.	freeze-thaw lysates prepared from strains of escherichia coli belonging to serogroups o138, o139, and o141 contained a principle (edema disease principle) which induced edema disease in swine. all freeze-thaw lysates contained endotoxic activity that tended to obscure the edema disease syndrome and methods were developed to reduce such activity. freeze-thaw lysates prepared from e. coli o139 induced the most characteristic edema disease syndrome. partially purified edema disease principle prepar ...	1974	4272954
experimental edema disease of swine (e. coli enterotoxemia). 3. pathology and pathogenesis.	experimental colibacillary (escherichia coli) enterotoxemia as described in this report mimics natural edema disease both clinically and in gross pathology. the histopathology is characterized by accumulations of non-inflammatory edema and by arteriopathy. the smaller arterial and arteriolar changes recorded here are similar to those described in natural edema disease. the vascular changes described in recovered cases of experimental colibacillary enterotoxemia concur with those reported in so-c ...	1974	4272956
the development of the flora of the alimentary tract in young animals.		1965	4285022
lipoyl dehydrogenase from saccharomyces cerevisiae. i. purification and some properties.		1965	4286290
nucleoside 5'-o-phosphorothioates as inhibitors for phosphatases.		1967	4294452
polynucleotidase activity of animal and plant tissue phosphodiesterases.		1968	4296154
dynamics of incidence of antibiotic-(chemotherapeutic-) resistant e. coli in pigs and types of polyresistance of the isolated strains depending on addition of aureovit12 c20 to food.		1969	4309834
[use of antibiotics in combination with antiperfringens serum in the treatment of experimental gas infection caused by cl. perfringens in association with escherichia coli].		1969	4314241
role of bacteria in modifying virulence of entamoeba histolytica. studies of amebae from axenic cultures.		1970	4318244
[permeability disorders in the central nervous system of the pig. ultrastructure of cerebrospinal angiopathy].		1972	4340050
conformation of oligoinosinates: chain-length dependence and comparison to other oligonucleotides.		1972	4340906
simplified radioimmunoassay for diagnostic serology.	a simplified, indirect radioimmunoassay is described for escherichia coli, vaccinia virus, and herpesvirus. the antigens were affixed to glass cover slips; thus both the primary and secondary reactions take place on the cover slips, and the unbound antiserum is easily separated from the bound antiserum by rinsing. rabbit or human immune sera were reacted with the antigens, and the primary immune complex was quantitated by a secondary reaction with (125)i-indicator globulin (anti-rabbit or anti-h ...	1972	4344958
the intestinal flora of pigs with special reference to clostridium perfringens.		1972	4353892
the production of ige and igg1 antibodies in guinea-pigs immunized with antigen and bacterial lipopolysaccharides.		1973	4354826
entamoeba histolytica: concurrent irreversible loss of infectivity-pathogenicity and encystment potential after prolonged maintenance in axenic culture in vitro.		1973	4355413
mutation in shigella flexneri resulting in loss of ability to penetrate hela cells and loss of glycerol kinase activity.	a colonial variant of a virulent shigella flexneri 2a has lost both virulence and glycerol kinase activity. it also has several other altered characteristics: lowered ability to oxidize tricarboxylic acid cycle intermediates, increased electrophoretic mobility, and decreased sensitivity to sodium lauryl sulfate. genetic analysis has revealed that the gene governing glycerol kinase activity in shigella has a different chromosomal locus than that from escherichia coli. furthermore, transduction of ...	1974	4363235
d- and l-alanylphosphatidylglycerols from mycoplasma laidlawii, strain b.		1969	4391533
metabolic regulation by chemical modification of enzymes.		1971	4399446
activation of the complement system by interferon inducers.		1972	4404904
[cross resistance of e. coli strains isolated from swine to nitrofuran compounds].		1972	4551588
the fate of e. coli organisms, strain a serotype o149:h10, in newborn piglets from sows immunized with an e. coli o149 vaccine.		1972	4553994
a new approach to the elucidation of the initial kinetics of neutral and acid deoxyribonucleases.		1972	4554645
comments on immunity in control of neonatal colibacillosis in pigs.		1972	4555392
a review of some effects on health and performance of variations in the physical form of the diet of the growing pig. ii. fibrous constituents and water level.		1972	4558593
acetyl coenzyme a carboxylase. iv. biotinyl prosthetic group-independent malonyl coenzyme a decarboxylation and carbosyl transfer: generalization to other biotin enzymes.		1972	4560496
[note on the vector role of birds of prey in the spreading of some bacterial diseases].		1972	4561874
lactoferrin--a bacteriostatic protein in human milk.		1972	4562237
[properdin research. 1. review of the properdin system and its problems; determination possibilities, assay of sera with high titer levels].		1972	4562974
[relationships between beta hemolytic escherichia coli and coli enterotoxemia in pigs. experiments and considerations].		1972	4562975
detection of endotoxin in commercial l-asparaginase preparations by complement fixation and separation by chromatography.		1972	4563138
production of diarrhea in pigs in response to escherichia coli enterotoxin.		1972	4565727
immunochemical studies of escherichia coli succinic thiokinase. effects of sulfhydryl reagents and other treatments on the enzyme.		1973	4567789
application of experimental keratoconjunctivitis shigellosa in chemotherapeutic evaluation of rifampicin to bacillary dysentery.		1972	4569214
[study of bdellovibrio bacteriovorus as 1 of the biological factors in the self-purification of surface waters].		1973	4572501
[permeation of ferritin on normal and colitoxin damaged vessels in the central nervous system of the pig].		1973	4573177
protection against enteric disease caused by escherichia coli--a model for vaccination with a virulence determinant?		1973	4573477
potentiometric and colorimetric methods for the assay of 2',3'-cyclic nucleotide 3'-phosphohydrolase.		1973	4574193
effect of prohibition of the use of tetracyclines in animal feeds on tetracycline resistance of faecal e. coli of pigs.		1973	4574725
the subunit structure of the escherichia coli k12 pyruvate-dehydrogenase complex. dihydrolipoamide-dehydrogenase component.		1973	4577854
contributions of the classical and alternate complement pathways to the biological effects of endotoxin.		1973	4578308
studies of the local immune response to pyelonephritis in the rabbit.		1973	4579139
escherichia coli antigens as dietary additives for oral immunisation of pigs: trials with pig creep feeds.		1973	4580504
the generalized shwartzman reaction in pigs induced by diet and single injection of disintegrated cells or partially purified endotoxin from escherichia coli.		1973	4580958
comparison of ampicillin and sulfachlorpyridazine in treatment of colibacillosis in swine.		1973	4581884