Publications

richard bright, pioneer epileptologist.		2012	3281059
abdominal pregnancy: current concepts of management.	nine cases of early and six cases of advanced abdominal pregnancy managed at the university of mississippi medical center over a 20-year period are reviewed. an incidence of one abdominal pregnancy in 4857 deliveries occurred in this series. a perinatal mortality rate of 83% and no maternal mortality were noted, in contrast to published rates of 40-95% and 0.5-18%, respectively. important current concepts of management include difficulty in diagnosis, predisposing risk factors, suggestive signs ...	2012	3281075
quality of commercially produced shigella serogrouping and serotyping antisera.	shigella grouping antisera from five manufacturers and typing antisera from two were purchased and evaluated with homologous and heterologous shigella strains in the slide agglutination test. only 31 of 73 (42%) antisera were satisfactory. in many instances, the antisera gave negative, as opposed to weak, reactions when they should have given strong positive reactions. four reagents cross-reacted with shigella strains. of the 19 polyvalent grouping antisera to subgroups shigella dysenteriae sero ...	1988	3281972
[electrical activity of the heart atria].		2012	3282619
cardiac nuclear medicine, present status, future hopes as seen from the view of a cardiologist.	the present techniques of nuclear medicine that are used in cardiology are critically evaluated. they are used mainly for the assessment of coronary circulation (measurement of regional flow and perfusion), on the determination of left ventricular muscle function (radionuclear ventriculography) and on the study of cardiac metabolism. the last-mentioned technique is unique insofar as (except for magnetic resonance imaging) there is no other method available to analyse myocardial metabolism noninv ...	1988	3282883
reaction of anti-hla-b monoclonal antibodies with envelope proteins of shigella species. evidence for molecular mimicry in the spondyloarthropathies.	immunologic cross-reactivity between enteric bacteria and the hla-b27 protein may play a role in the etiology of reiter's syndrome and reactive arthritis. the reactivity of two anti-b27 mab (b27m1 and b27m2) with envelope proteins of shigella flexneri isolated from reiter's syndrome patients was studied by western blot analysis. proteins with an apparent mr of approximately 36 and 23 kda reacted with both mab in ascites. mab against related hla class i ag b7 and b40 did not react with the 23 kda ...	1988	3283236
serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an israeli military population.		1988	3283258
chiasmal compression caused by a catheter in the suprasellar cistern.		2009	3285696
conservation of an atp-binding domain among reca proteins from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli k-12 and b/r.	the purified reca proteins encoded by the cloned genes from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli b/r were compared with the reca protein from e. coli k-12. each of the proteins hydrolyzed atp in the presence of single-stranded dna, and each was covalently modified with the photoaffinity atp analog 8-azidoadenosine 5'-triphosphate (8n3atp). two-dimensional tryptic maps of the four heterologous reca proteins demonstrated considerable structural conservation ...	1988	3286605
[clinico-immunological characteristics of mixed intestinal infections in children].		1988	3287323
muscular contraction.		2012	3288085
[changes in the degree of sensitivity to antibiotics of shigella isolated from patients with dysentery in a city infectious disease hospital over the past 8 years].	changes in sensitivity of shigella and in particular shigella flexneri isolated from dysentery patients in a city infection hospital within 8 years i.e. from 1977 to 1985 were followed. it was shown that the changes were to the greater extent connected with preferable use of certain antibiotics in the hospital.	1988	3288150
ifosfamide and vp-16213 combination chemotherapy combined with ablative chemotherapy and autologous marrow transplantation as salvage treatment for malignant lymphoma.	eighteen patients with high-grade malignant lymphoma were treated with ifosfamide-vp16213 combinations after failing to respond completely or after relapsing on chop-like therapy. responders to the salvage therapy were subsequently treated with ablative chemotherapy (bcnu, vp-16213, ara-c and melfalan) and autografted. of these 18 patients six were in relapse, six were partial responders and six failed chop-like therapy. there were two complete remissions and seven partial responses to the ifosf ...	2011	3289942
suggestion to supplement shigella flexneri classification scheme with the subserovar shigella flexneri 4c: phenotypic characteristics of strains.	a new serovar of shigella flexneri has been isolated with increasing frequency in the ussr. it has the antigenic formula iv:7,8. we suggest that it be incorporated into the classification scheme as s. flexneri subserovar 4c. the 212 strains of this proposed subserovar examined to date display biochemical and serological properties typical of the species, are sensitive to the genus-specific bacteriophage, and cause keratoconjunctivitis in the sereny test.	1988	3290245
nonunion of intercondylar eminence fracture of the tibia.	an unusual case of symptomatic nonunion of an intercondylar eminence fracture in an adult is presented. the nonunion was successfully treated using internal fixation and bone grafting.	2009	3290508
salmonellal mycotic abdominal-aortic aneurysm.	a patient is described with a mycotic abdominal-aortic aneurysm that was caused by salmonella typhimurium, who presented to hospital four months after a urinary-tract infection that was caused by the same organism. the urinary-tract infection may have resulted from an episode of transient salmonellal bacteraemia, the significance of which was not appreciated. the pathogenesis, clinical features, treatment and prognosis of arteritis due to salmonella species are reviewed. the early diagnosis and ...	1988	3292882
salmonellal mycotic abdominal-aortic aneurysm.	a patient is described with a mycotic abdominal-aortic aneurysm that was caused by salmonella typhimurium, who presented to hospital four months after a urinary-tract infection that was caused by the same organism. the urinary-tract infection may have resulted from an episode of transient salmonellal bacteraemia, the significance of which was not appreciated. the pathogenesis, clinical features, treatment and prognosis of arteritis due to salmonella species are reviewed. the early diagnosis and ...	1988	3292882
redressing the balance.		2012	3292931
hormonal abnormalities in obesity.	we have found a number of interesting hormonal abnormalities in obese men and women: 1) obese women have normal levels of estrone, total estradiol, and total testosterone, but as a consequence of their subnormal levels of shbg, their levels of free estradiol and free testosterone are significantly elevated. 2) massive weight loss in obese women (to still elevated weight) results in normalization of the previously elevated free estradiol and free testosterone. 3) obese women have normal plasma dh ...	2011	3293358
hormonal abnormalities in obesity.	we have found a number of interesting hormonal abnormalities in obese men and women: 1) obese women have normal levels of estrone, total estradiol, and total testosterone, but as a consequence of their subnormal levels of shbg, their levels of free estradiol and free testosterone are significantly elevated. 2) massive weight loss in obese women (to still elevated weight) results in normalization of the previously elevated free estradiol and free testosterone. 3) obese women have normal plasma dh ...	2011	3293358
nonsteroidal anti-inflammatory drugs, and hypertension.		2009	3293496
demetrio sodi-pallares: the man and his thought.		1988	3293862
[technic of the peroperative use of doppler in neurosurgery].	intraoperative doppler exploration during neurosurgery was used during treatment of intracranial aneurysms, arteriovenous malformations (avm) and cerebral revascularization by extra-intra cranial anastomosis (eica). it was also employed to study behavior of cortical arteries under different conditions. during treatment of aneurysms, doppler can show, prior to clipping, whether blood flow through. the flow is regular--spasm of supply artery provokes acceleration of blood rate. after clipping it i ...	2005	3294324
effects of marine mammal parasites on human health.		1987	3294653
molecular cloning of invasion plasmid antigen (ipa) genes from shigella flexneri: analysis of ipa gene products and genetic mapping.	tn5-tagged invasion plasmid dna (pwr110) from shigella flexneri serotype 5 (strain m90t) was cloned into the expression vector lambda gt11. recombinant phage (lambda gt11sfl) expressing pwr110-encoded polypeptide antigens were identified by using rabbit antisera directed against s. flexneri m90t invasion plasmid antigens. antigens encoded by lambda gt11sfl recombinant phage were characterized by reacting affinity-purified antibodies, eluted from nitrocellulose-bound plaques of lambda gt11sfl rec ...	1987	3294797
an aminoacyl-trna synthetase complex in escherichia coli.	aminoacyl-trna synthetases from several strains of escherichia coli are shown to elute as a high-molecular-weight complex on 6% agarose columns (bio-gel a-5m). in contrast, very little synthetase activity was observed in such complexes on sephadex g-200 columns, suggesting that these enzymes may interact with or are dissociated during chromatography on dextran. the size of the complex observed on bio-gel a-5m was influenced by the method of cell breakage and the salt concentrations present in bu ...	1987	3294804
an accessory protein identical to mouse egasyn is complexed with rat microsomal beta-glucuronidase and is identical to rat esterase-3.	we report biochemical, immunological, and genetic studies which demonstrate that an accessory protein with the essential features of mouse egasyn is complexed with and stabilizes a portion of beta-glucuronidase in microsomes of rat liver. the accessory protein exists as a complex with beta-glucuronidase since it coprecipitates with beta-glucuronidase after treatment of extracts with a specific beta-glucuronidase antibody. the two proteins are associated by noncovalent bonds since they are easily ...	1987	3294829
bacterial invasion of fibroblasts induces interferon production.	although bacteria and/or bacterial products have been shown to induce interferon (ifn) production in cells of the immune system, the ability of non-lymphoid cells to produce ifn in response to bacterial products and/or bacterial invasion is currently unknown. in this study we examined murine and human fibroblasts for their ability to produce ifn in response to challenge with the invasive bacteria shigella flexneri and enteroinvasive escherichia coli. both human and murine primary cell cultures p ...	1987	3295042
toxic megacolon complicating shigellosis.		1987	3295219
[dynamics of bacterial polysensitization in acute dysentery in children depending on the species of the causative agent].	studies on polysensitization, evaluated by the neutrophil damage index, have been made with the use of dysenterin and the allergens of hemolytic staphylococci, enterococci and escherichia coli. the studies have revealed that both specific and nonspecific sensitization to hemolytic staphylococci and enterococci is higher in dysentery caused by shigella flexneri than in dysentery caused by s. sonnei and has the tendency to increase in the course of the disease.	1987	3296580
[gardnerella vaginalis in nonspecific vaginitis].		1987	3296818
humoral response in mice immunized with outer membrane proteins of shigella flexneri.	intraperitoneal immunization of mice with outer membrane proteins (omp) of sh. flexneri induced in the animals a synthesis of specific antibodies. their level determined by elisa test was found to be relatively low in the sera of animals immunized with a single dose (10 micrograms) of omp; it was markedly higher in mice immunized with two doses of omp, and very high after three fold immunization. the specific antibodies maintained in the animals for 8-16 weeks after immunization. anti-omp sera g ...	1986	3296993
behavior of beta 2-microglobulin in patients with chronic renal failure undergoing hemodialysis, hemodiafiltration and continuous ambulatory peritoneal dialysis (capd).	beta 2-microglobulin (beta 2-m) is the major component of a new form of amyloid deposit found in carpal tunnel syndrome and dialysis arthropathy of long-term hemodialysis patients. in 52 patients on maintenance hemodialysis, serum beta 2-m concentration was elevated to 37.9 +/- 1.4 (normal 1.2 +/- 0.6) mg/l. it was correlated with the time on hemodialysis (r = 0.43, p less than 0.01) and was inversely correlated with residual renal function (r = 0.87, p less than 0.001). in 20 patients on capd, ...	2012	3297439
examination by ultrasound of legg-calvé-perthes disease.	eleven patients with legg-calvé-perthes disease (lcp) were examined ultrasonographically for their femoral head deformity. the outline of the cartilaginous femoral head was well demonstrated, and the image obtained corresponded to that observed by arthrography. using ultrasonography, a simple method was developed to determine the rate of deformity due to lcp. ultrasonography does not have the hazards of x-ray and is useful for the diagnosis of lcp.	2011	3297450
examination by ultrasound of legg-calvé-perthes disease.	eleven patients with legg-calvé-perthes disease (lcp) were examined ultrasonographically for their femoral head deformity. the outline of the cartilaginous femoral head was well demonstrated, and the image obtained corresponded to that observed by arthrography. using ultrasonography, a simple method was developed to determine the rate of deformity due to lcp. ultrasonography does not have the hazards of x-ray and is useful for the diagnosis of lcp.	2011	3297450
epinephrine, glucose, and lactate infusion in exercising adrenodemedullated rats.	the purpose of this study was to determine the metabolic function of the marked increase in plasma epinephrine which occurs in fasted rats during treadmill exercise. fasted adrenodemedullated (adm) and sham-operated (sham) rats were run on a rodent treadmill (21 m/min, 15% grade) for 30 min or until exhaustion. adm rats were infused with saline, epinephrine, glucose, or lactate during the exercise bouts. adm saline-infused rats showed markedly reduced endurance, hypoglycemia, elevated plasma ins ...	1987	3298192
rubens peale and his spectacles.		2012	3298707
[diagnosis, prevention and treatment of drug allergy].		2012	3299343
the protein subunits of the double-stranded rna dependent rna polymerase and methyltransferase of the cytoplasmic polyhedrosis virus of silkworm, bombyx mori.	the particles of cpv of silkworm contain double-stranded rna polymerase and methyltransferase. it was reported in a previous paper that the genome-enzyme complex could be isolated. the genome-enzyme complex shows high enzyme activity of rna polymerase and methyltransferase in spite of the fact that it consists of only 5 percent of the protein. in order to clarify the protein subunits of the rna polymerase and methyltransferase, two methods were adopted. the sds-polyacrylamide gel electrophoretog ...	1986	3299695
erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation.	the avian acute leukemia virus e26 induces a mixed erythroid-myeloid leukemia in chickens and carries two distinct oncogenes, v-myb and v-ets. recently, a novel gene named erg, closely related to the v-ets oncogene, was identified in human colo 320 cells and the nucleotide sequence of its approximately 5.0-kilobase transcript, erg 1 was determined. in the present study, the nucleotide sequence of the alternatively spliced transcript, erg 2, was found to differ from erg 1 by a splicing event that ...	1987	3299708
[growth and development of a population of the causative agent during an infection].		1987	3299739
comparative bio-availability of theophylline whole and halved sustained-release tablets.	in a randomised, multiple-dose, cross-over study in 14 healthy volunteers, plasma theophylline concentrations were compared during a 12-hour dosing interval after repeated administration of theophylline (euphyllin retard; byk gulden) as whole and halved tablets. bio-availability of theophylline from the halved tablets relative to the whole tablets was: 116% (100%, 134%) for the extent of absorption as judged by the area under the concentration time curve (auc) and 115% (99%, 135%) for the rate o ...	2012	3299763
childhood cancer.	the literature generally supports the evolving recognition that childhood cancers are influenced by the environment. this article discusses specific childhood cancers in regard to paternal and maternal occupation.	2012	3299786
multiple enteric pathogens in a patient with diarrhoea.	a woman who recently arrived in canada from india developed a febrile, diarrhoeal illness. stool culture revealed the presence of salmonella typhi, campylobacter fetus subspecies jejuni and shigella flexneri. concurrent infection with these three pathogens does not appear to have been previously reported. the possibility of multiple pathogens should be considered in travellers who fail to respond to treatment of a single organism.	1987	3299934
corneal ulcer caused by shigella flexneri in an infant.		1987	3300355
live dysentery vaccine "vadizen" (t32-istrati) immunogenicity against shigella-like challenge in animals.		1986	3300598
ultrastructural study on the bacterial symbiont in giardia lamblia.		1986	3300600
[reye-like syndrome due to shigella flexneri in a child].		1987	3301584
treatment of bacillary dysentery: a comparison between enoxacin and nalidixic acid.	a prospective randomized study has been conducted in rwanda to compare the efficacy of enoxacin versus nalidixic acid for the treatment of bacillary dysentery in adults. seventeen patients received nalidixic acid and 21 received enoxacin. all isolates (37 shigella, 1 campylobacter) were sensitive in vitro to the two drugs. all patients showed a favourable clinical and bacteriological response and the results obtained with both drugs were comparable. enoxacin seems to be a good alternative to nal ...	1987	3301783
clinical presentation of shigellosis during the 1984 epidemic of bacillary dysentery in west bengal.		1987	3301795
shigellosis in bangladesh: a reply.		1987	3302055
transition to flight nursing: three experiences.		2012	3302460
[the men behind the syndrome: johannes peutz and harold jeghers. the explorers of an underdiagnosed condition with intestinal polyps and mucocutaneous pigmentations].		2012	3302567
retardation of cell cycle progression in yeast cells recovering from dna damage: a study at the single cell level.	pedigree analyses of individual yeast cells recovering from dna damage were performed and time intervals between morphological landmark events during the cell cycle (bud emergence and cell separation), were recorded for three generations. the associated nuclear behavior was monitored with the aid of dapi staining. the following observations were made: all agents tested (x-rays, mms, ems, mnng, nitrous acid) delayed the first bud emergence after treatment, which indicates inhibition of the initia ...	1987	3302599
production of monospecific antibodies to a low-abundance hepatic membrane protein using nitrocellulose immobilized protein as antigen.	membrane proteins from primary cultures of rat hepatocytes were separated by two-dimensional polyacrylamide gel electrophoresis. the proteins were transferred to nitrocellulose paper which was then dissolved in dimethyl sulfoxide and this mixture was used as a primary immunogen in rabbits. subsequent immunizations were performed using nonsolubilized protein immobilized on nitrocellulose paper. a monospecific polyclonal antibody was generated against a specific mitochondrial membrane protein (mp- ...	1987	3304007
molecular cloning and expression of a synthetic dna coding for the antimicrobial protein of bull seminal plasma.	a dna carrying the coding sequence for the antimicrobial protein from bull seminal plasma (sap) was obtained by enzymic ligation of six synthetic oligonucleotides. the 162 bp synthetic dna fragment was cloned into the c-terminal part of the lacz-gene employing the vector pur289. expression in e. coli in the presence of the inducer isopropylthiogalactoside (iptg) led to the formation of a fusion protein, which was shown by immuno-blotting to contain immuno-reactive antimicrobial protein. approxim ...	1987	3304335
[reaction of the hematopoietic system in mice to the administration of virulent and avirulent strains of shigella flexneri 2a].	the influence of live bacteria and antigenic preparations of virulent and avirulent stains of shigella flexneri 2a on the endogenous splenic colony formation in murine hematopoietic cells has been studied. the different stimulating activity of live microbial cells of virulent and avirulent strains shigella flexneri 2a and their antigenic preparations on the endogenous colony formation has been shown. the effect observed depends on the preparation doses and time of their administration before irr ...	1987	3304434
[demonstration of anti-laminin antibodies in the serum of healthy subjects].	antibodies directed against laminin, a glycoprotein of basement membranes, have been sought for in the sera of 347 healthy subjects by a method relying on the agglutination of laminin-coated latex particles. fifty-five subjects (15.9%) hae been found to be positive, 37 with a titre of 2, 14 with a titre of 4 and 4 with a titer of 8. applied to 106 patients whose a renal biopsy had been examined by immunofluorescence, the test yielded positive results in 91% of patients with linear deposits as co ...	2012	3304440
a new chromogenic test for the detection of urokinase in the genus shigella.	a simple test for detection of urokinase in shigella is described. the test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mm solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (chromozym u). enzymatic activity is revealed by formation of a yellow colour after 24 h of incubation at 37 degrees c. the test is able to differentiate serotypes of shigella dysenteriae, shigella flexneri, shigella boydii. the results suggest the possibility of incl ...	1987	3306294
okt3 rescue in refractory renal rejection.	a community hospital-based transplant program participated in the study of orthoclone okt3 as a treatment for refractory renal rejection. a total of 16 patients receiving varied oral immunosuppressive regimens, and developing steroid-resistant acute rejection, were treated with okt3. thirteen of the 16 patients completed a 10-day course of therapy with reversal of rejection in all 13. rerejection occurred in 1 of the 13 patients; the remaining 12 have normal renal function. fever, chills, and di ...	2012	3306423
chronobiology and epidemiology.	epidemiology and chronobiology are two emerging scientific disciplines of the 20th century. in the united states and certain european and asian countries, epidemiology is a well-developed science; however, in many countries the field is not yet well practiced. too, in several european countries and certain centers in the united states, chronobiology is quite well known and respected as a science. yet, in many countries this field is just now being recognized. although epidemiologists are concern ...	1987	3306581
[morphological changes in the lungs after single whole-body irradiation in rabbits].	morphological changes in rabbit lungs were studied after whole-body nonuniform irradiation (24 gy) the head and the abdomen being shielded. acute pneumonitis was shown to develop between the 17th and the 24th day after irradiation. no pulmonary fibrosis was registered 60 days following irradiation. embolised megakaryocytes were found in the lung capillaries between the 8th and the 24th day after irradiation.	1987	3306764
warfarin and the biochemistry of the vitamin k dependent proteins.	we have reviewed the biochemistry of the normal and warfarinized vitamin k-dependent coagulation proteins, both individually and as members of their respective macromolecular enzyme complexes. much has been learned in the past 10-15 years about the molecular mechanisms of coagulation. however, we have only scratched the surface and are beset by a number of interesting challenges. clearly, we must begin to dissect the other vitamin k-dependent macromolecular enzyme complexes as has been done for ...	2012	3310538
evaluation of bronchodilator responsiveness in mechanically ventilated patients.	airway pressure, flow, and volume were measured before and after administration of aerosolized metaproterenol during controlled mechanical inflation and stepwise deflation of the relaxed respiratory system in 13 mechanically ventilated patients. an increase in passive expiratory flow at constant respiratory system recoil pressure was considered evidence of bronchodilatation. in 10 patients, at a respiratory system recoil pressure of 6 cm h2o (vp6), expiratory flow increased 21 to 500% above preb ...	2012	3310772
[steroidogenesis in ovarian tumors].		2012	3311390
atrio-ventricular block associated with shigella flexneri infection.		1987	3311739
entry of shigella flexneri into hela cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation.	the enteroinvasive bacterium shigella flexneri expresses a plasmid-mediated capacity to penetrate into nonphagocytic cells. by using 7-nitrobenz-2-oxa-1,3-diazole-phallacidin (nbd-phallacidin), a fluorescent dye which specifically stains microfilaments, we observed condensations of filamentous actin underneath the plasma membrane of hela cells which interacted with the invasive isolate m90t. as demonstrated by indirect immunofluorescence with the antimyosin monoclonal antibody cc-212, myosin acc ...	1987	3312007
introduction of shigella flexneri 2a type and group antigen genes into oral typhoid vaccine strain salmonella typhi ty21a.	for protection against dysentery caused by shigella flexneri 2a, an in vivo-constructed recombinant plasmid with genes specifying the s. flexneri type and group antigens located near the pro (min 6) and his (min 44) chromosomal markers, respectively, was made and transferred to the gale salmonella typhi strain ty21a. strain ty21a carrying this recombinant plasmid was shown by immunological and biochemical analyses to express the s. flexneri 2a type and group antigens. mice immunized with this va ...	1987	3312013
expression of campylobacter jejuni invasiveness in cell cultures coinfected with other bacteria.	enteroinvasive salmonella, shigella, and escherichia coli strains were found to exert an effect which rendered campylobacter jejuni capable of intracellular localization in epithelial cells in vitro. when monolayers of hep-2 or a-549 cells were challenged with pure cultures of c. jejuni or campylobacter coli, none of the eight strains tested invaded the cells. in contrast, four of these strains were able to localize intracellularly when the cells were challenged with a mixture of campylobacters ...	1987	3312015
design of skin flaps with a new technique using templates.	patterned templates were constructed to assist in planning, performing, and teaching skin flap surgery. templates can be used to design geometrically accurate flaps and to consider different flap orientation strategies. they can be used to align flap tension forces in proper relationship with relaxed skin tension lines.	2012	3312330
clinical use of differential continuous positive airway pressure in the treatment of unilateral acute lung injury.	in some instances of unilateral acute lung injury (ali) refractory to conventional ventilatory support, the intact lung is still able to ensure an efficient co2 washout, the concomitant hypoxaemia being due to the loss of volume of the injured parenchyma. in these cases, the administration of a sufficient selective continuous distending pressure by means of differential continuous positive airway pressure may restore to normal the resting volume and thus the ventilatory performance of the affect ...	2012	3312355
[bacillary dysentery 1985].		1987	3313536
hemolytic uremic syndrome associated with shigellosis: report of two cases.	two patients with hemolytic uremic syndrome admitted to udornthani hospital, thailand, were reported. the preceding illness was shigellosis. the stool culture was positive for shigella dysenteriae in one patient and shigella flexneri in another. the management was successful with peritoneal dialysis in one and symptomatic treatment in another. both patients had complete recovery.	1987	3313740
[prospects for using thymalin in treating bacterial intestinal infections].		1987	3314133
technological investigations with attenuated strains of shigella for production of live vaccines. 1. cultivation in a fermenter of an attenuated strain s. flexneri 2a with two markers.	a method was developed for cultivation of the strain shigella flexneri 2a 77 with two attenuated markers. it ensures the preservation of the initial properties of the strain. the regimen for control of dissolved oxygen level was optimized. it was established that yeast extract is a necessary component of the nutritive medium used. the role of the phase and quantity of the inoculum for growth of the bacterial population has been clarified. fresh fermenter culture, applied in rats, shows a high im ...	1987	3314220
shigella bacteremia in adults. a report of five cases and review of the literature.	shigella bacteremia is rare, occurring mainly in children. we describe five adult patients with shigella bacteremia and review data on 22 cases reported in the english-language medical literature. eighteen (67%) of 27 patients had either an underlying condition or were aged older than 65 years. most patients had clinical signs of acute febrile gastroenteritis. however, in six patients, the organism was not isolated from stool. species isolated from blood included shigella flexneri in 11 patients ...	1987	3314766
a 2d-1h-n.m.r. study of some shigella flexneri o-polysaccharides.	a 1h-n.m.r. study of the o-polysaccharides from different types of shigella flexneri has been performed. with the aid of 2d-n.m.r. techniques, namely, j-resolved, spin-spin correlation, and noesy experiments, most of the structural features of these polysaccharides could be deduced. sequences could generally be obtained from the noesy experiments. when using a prolonged mixing time in these experiments, cross-peaks due to spin diffusion from one anomeric proton to the anomeric proton of an adjac ...	1987	3315202
glucoregulatory effects of bombesin in lean and genetically obese hyperglycaemic (ob/ob) mice.	1. plasma glucose and insulin responses to bombesin were examined in 12-15-week-old 12 hr fasted lean and genetically obese hyperglycaemic (ob/ob) mice. 2. bombesin (1 mg/kg ip) produced a prompt but transient increase of plasma insulin in lean mice (maximum increase of 50% at 5 min), and a more slowly generated but protracted insulin response in ob/ob mice (maximum increase of 80% at 30 min). plasma glucose concentrations of both groups of mice were increased by bombesin (maximum increases of 4 ...	2012	3315420
natural selection and the heritability of fitness components.	the hypothesis that traits closely associated with fitness will generally possess lower heritabilities than traits more loosely connected with fitness is tested using 1120 narrow sense heritability estimates for wild, outbred animal populations, collected from the published record. our results indicate that life history traits generally possess lower heritabilities than morphological traits, and that the means, medians, and cumulative frequency distributions of behavioural and physiological trai ...	2012	3316130
moses maimonides and air pollution.		2012	3317154
[biological properties of opportunistic microorganisms isolated from patients with acute intestinal diseases].	the comparative study of the incidence of the pathogenicity markers (dnaase, rnaase, phosphatase and hemolytic activity) in shigellae and salmonellae, acknowledged as the causative agents of intestinal infections, and in opportunistic bacteria isolated from the feces of patients with acute intestinal diseases and healthy persons has been made. the study has revealed that dnaase and rnaase activity occurs most frequently in shigella flexneri, in salmonellae and in opportunistic enterobacteria iso ...	1987	3318225
aspects of histamine metabolism.		2012	3318321
shigellosis at a caribbean resort. hamburger and north american origin as risk factors.	during a three-week period in 1984, 339 tourists and expatriate employees with diarrhea visited the infirmary at a caribbean resort club. epidemiologic studies suggested that over 60% of the 1,893 tourists at the resort club during that time may have been ill. shigella flexneri 4a was isolated from seven of 18 stool specimens. a few cases of diarrheal illness occurred at the resort club before the onset of the outbreak, which was temporally related to illness in a butcher. north american residen ...	1987	3318410
double-blind clinical trial of s-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis.	thirty-six subjects with osteoarthritis of the knee, the hip, and/or the spine were enrolled in a randomized double-blind study. patients received a daily oral dose of 1,200 mg of s-adenosylmethionine (same) or 1,200 mg of ibuprofen for four weeks. morning stiffness, pain at rest, pain on motion, crepitus, swelling, and limitation of motion of the affected joints were assessed before and after treatment. the total score obtained by the evaluation of all the individual clinical parameters improve ...	2012	3318445
emotional responses of pregnant women to chorionic villi sampling or amniocentesis.	seventy-four "high-risk" pregnant women interested in participating in a clinical trial comparing chorionic villi sampling and amniocentesis were initially assessed on five background measures and for anxiety, depression, hostility, and concern about abortion. the 61 women who then agreed to be randomized into the chorionic villi sampling and amniocentesis groups were assessed three additional times between 9 and 22 weeks' gestational age. physical discomfort experienced during the diagnostic pr ...	2012	3318465
arteriolar oxygen reactivity: where is the sensor?	the hypothesis that arterioles are intrinsically sensitive to oxygen was tested by comparing arteriolar diameter responses with local and global po2 changes in superfused hamster cheek pouch preparations. local po2 changes were produced by microapplication of fluid onto the surface of occluded or unoccluded aparenchymal arterioles or by cannulation and perfusion of arterioles in situ. global changes refer to po2 changes in the superfusate flowing over the entire preparation. local, effective po2 ...	2012	3318502
[medico-genetic studies of human provisional organs].		1987	3318529
improved immunohistochemical staining of angiotensin ii in rat brain using affinity purified antibodies.	recent immunohistochemical studies that have sought to detect angiotensin ii/iii (aii/aiii) immunoreactive material in the brain have been forced to rely on a small number of antisera because most aii/aiii antibodies have unexplainably proved unsuitable for immunohistochemistry. although extremely useful tools, these antisera have suffered from high background staining. the purpose of this study was to re-examine and characterize the staining using the most popular aii/aiii antiserum (denise) be ...	1987	3319044
kinetics and dynamics of prednisolone.		2012	3319533
psychogenic habit cough: review and case reports.	psychogenic habit cough--a condition that can be debilitating if it extends over a period of years--has been described in both pediatric and adolescent populations, but not in adults. the authors review the cases of 4 adult patients with this condition, review the available pediatric/adolescent literature, and make suggestions for the direction of future research. in some cases, psychogenic habit cough in adults can be successfully treated with a combination of psychotherapy, relaxation therapy, ...	2012	3320033
the role of extracellular proteases in cell proliferation and differentiation.	proteases have been shown to be capable of inducing two of the most fundamental biologic processes: mitogenesis and cellular differentiation. their proteolytic activity has been the most widely studied enzymatic activity implicated in inducing these processes. protease induction of mitogenesis is a major system for studying the control of this process and studies of possible transmembrane signals have been initiated. proteases have only recently begun to be used as tools for probing the inductio ...	2012	3320517
[glomerulopathies and neoplasms].		2012	3320600
management of progressive renal failure: the role of dietary manipulations.		2012	3321007
pathogenesis of shigella infections.		1987	3321018
comparative aspects of canine and human atopic dermatitis.		1987	3321301
novel oral vaccines: the effectiveness of cloned gene products on inducing secretory immune responses.		1987	3321939
inhibition of enteropathogenic escherichia coli (strain rdec-1) adherence to rabbit intestinal brush borders by milk immune secretory immunoglobulin a.		1987	3321942
enhancement of the secretory iga response to enteropathogens.		1987	3321943
[function of the kidneys and the renin-aldosterone system in women before and after use of intrauterine contraceptive devices].	conflicting opinions exist concerning the use of various birth control methods for women suffering from kidney diseases. some researchers think kidney diseases are a contraindication for the use of iud; since iuds may cause inflammatory processes; others think that preventive therapy of extragenital diseases may make the use of iud possible. the article studies the functional condition of the urinary system and various hormone levels (renin, aldosterone, vasopressin, cortisol) in women using an ...	2011	3322076
plasmid-mediated contact haemolytic activity in shigella species: correlation with penetration into hela cells.	the main feature of virulent strains of shigella is their ability to invade eucaryotic cells. this phenotype is both plasmid-mediated and temperature-regulated. in the present report, we demonstrate a plasmid-mediated and temperature-regulated haemolytic activity in s. flexneri, s. dysenteriae and s. sonnei. detection of this haemolytic activity requires centrifugation of suspensions containing bacteria and erythrocytes, followed by incubation of the pellets at 37 degrees c. no soluble intra- or ...	1986	3322171