Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| mechanisms of tritrichomonas foetus pathogenicity in cats with insights from venereal trichomonosis. | almost 20 years has passed since trichomonosis was first recognized as a potential cause of diarrhea in domestic cats. despite progress in confirming disease causation, developing means for diagnosis, and identifying approaches to treatment of the infection, we still know very little about how this parasite causes diarrhea. with increasing recognition of resistance of trichomonosis to treatment with 5-nitroimidazole drugs, new treatment strategies based on an understanding of disease pathogenesi ... | 2017 | 26946069 |
| correlation between trichomonas vaginalis and concurrency: an ecological study. | objective. there is a large variation in the prevalence of trichomonas vaginalis (tv) between different countries and between racial groups within countries. sexual partner concurrency may play a role. we investigate the correlation between the prevalence of sexual partner concurrency and tv prevalence. methods. spearman's correlation to assess relationship between tv prevalence in women and point prevalence of concurrency in men in (1) 11 countries with comparable data (concurrency data from wh ... | 2016 | 26949392 |
| influence of 120 kda pyruvate:ferredoxin oxidoreductase on pathogenicity of trichomonas vaginalis. | trichomonas vaginalis is a flagellate protozoan parasite and commonly infected the lower genital tract in women and men. iron is a known nutrient for growth of various pathogens, and also reported to be involved in establishment of trichomoniasis. however, the exact mechanism was not clarified. in this study, the author investigated whether the 120 kda protein of t. vaginalis may be involved in pathogenicity of trichomonads. antibodies against 120 kda protein of t. vaginalis, which was identifie ... | 2016 | 26951982 |
| prevalence of trichomonas vaginalis in women visiting 2 obstetrics and gynecology clinics in daegu, south korea. | this study explored epidemiological trends in trichomoniasis in daegu, south korea. wet mount microscopy, pcr, and multiplex pcr were used to test for trichomonas vaginalis in vaginal swab samples obtained from 621 women visiting 2 clinics in daegu. of the 621 women tested, microscopy detected t. vaginalis in 4 (0.6%) patients, pcr detected t. vaginalis in 19 (3.0%) patients, and multiplex pcr detected t. vaginalis in 12 (1.9%) patients. testing via pcr demonstrated high sensitivity and high neg ... | 2016 | 26951983 |
| trichomonas vaginalis induces il-1β production in a human prostate epithelial cell line by activating the nlrp3 inflammasome via reactive oxygen species and potassium ion efflux. | trichomonas vaginalis is a sexually transmitted protozoan parasite that causes vaginitis in women, and urethritis and prostatitis in men. il-1β is synthesized as immature pro-il-1β, which is cleaved by activated caspase-1. caspase-1 is, in turn, activated by a multi-protein complex known as an inflammasome. in this study, we investigated the inflammatory response of a prostate epithelial cell line (rwpe-1) to t. vaginalis and, specifically, the capacity of t. vaginalis to activate the nlrp3 infl ... | 2016 | 26959386 |
| frequency of human immunodeficiency virus (hiv) in trichomonas vaginalis infected women in badagry, lagos, nigeria. | the interaction between hiv and trichomonas vaginalis infection has been widely studied in most developed countries but with scanty information in sub-saharan africa. while many of these studies have examined the prevalence of t. vaginalis infection in hiv positive individuals, no study in nigeria has shown the effect of t. vaginalis on hiv transmission. therefore, the study aimed to determine the occurrence of hiv in t. vaginalis infected women. | 2017 | 26962485 |
| [usefulness of conventional polymerase chain reaction for the detection of mycoplasma hominis, ureaplasma spp. and trichomonas vaginalis in female outpatient's genital samples]. | trichomonas vaginalis, mycoplasma hominis and ureaplasma spp. are microorganisms responsible for genitourinary and pregnancy pathologies. nucleic acid amplification methods have shown several advantages, but have not been widely studied for the detection of these microorganisms. | 2016 | 26965874 |
| pelvic examination at the 6-week postpartum visit after cesarean birth. | the objective of this study was to assess the utility of the pelvic examination at the 6-week postpartum visit after cesarean birth. | 2016 | 26971582 |
| ureaplasma urealyticum: presence among sexually transmitted diseases. | the aim of this study was to detect the presence of chlamydia trachomatis, neisseria gonorrhoeae, mycoplasma genitalium, mycoplasma hominis, trichomonas vaginalis, and ureaplasma urealyticum in genital specimens of symptomatic patients. this study also examined the role of u. urealyticum in infections of the lower genital tract. cervical and urethral samples from 96 patients (46 males, 50 females) were tested using the seeplex((®)) std6 ace kit. consent forms were received and a questionnaire wa ... | 2017 | 27000449 |
| antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2h-indazoles. | two series of new 5-nitroindazole derivatives, 1-substituted 2-benzylindazolin-3-ones (6-29, series a) and 3-alkoxy-2-benzyl-2h-indazoles (30-37, series b), containing differently functionalized chains at position 1 and 3, respectively, have been synthesized starting from 2-benzyl-5-nitroindazolin-3-one 5, and evaluated against the protozoan parasites trypanosoma cruzi and trichomonas vaginalis, etiological agents of chagas disease and trichomonosis, respectively. many indazolinones of series a ... | 2016 | 27017556 |
| caatinga plants: natural and semi-synthetic compounds potentially active against trichomonas vaginalis. | trichomonas vaginalis causes trichomoniasis; the most common but overlooked non-viral sexually transmitted disease worldwide. the treatment is based at 5'-nitroimidazoles, however, failure are related to resistance of t. vaginalis to chemotherapy. caatinga is a uniquely brazilian region representing a biome with type desert vegetation and plants present diverse biological activity, however, with few studies. the aim of this study was to investigate the activity against t. vaginalis of different ... | 2016 | 27020521 |
| prevalence and risk factors of three curable sexually transmitted infections among women in nairobi, kenya. | sexually transmitted infections (stis) are a major public health problem, especially in developing countries. the complications of untreated stis in the female genital tract and their role in adverse pregnancy and perinatal outcomes have been well documented. the prevalence of stis in kenya among women in the general population has not been extensively studied and there is a lack of guidelines for screening of non-pregnant women. knowledge of the prevalence of curable stis among this population ... | 2016 | 27026347 |
| detection of hpv and co-infecting pathogens in healthy italian women by multiplex real-time pcr. | several pathogens can be transmitted sexually and are an important cause of morbidity among sexually active women. the aim of the study was to detect the presence of human papillomavirus (hpv), chlamydia trachomatis (ct), neisseria gonorrhoeae (ng), trichomonas vaginalis (tv), mycoplasma hominis (mh), mycoplasma genitalium (mg), ureaplasma urealyticum (uu), and ureaplasma parvum (up) in a group of 309 healthy women enrolled at the san camillo - forlanini hospital of rome by using two multiplex r ... | 2016 | 27031891 |
| association of genital infections other than human papillomavirus with pre-invasive and invasive cervical neoplasia. | human papillomavirus (hpv) is a well-established causative agent of malignancy of the female genital tract and a common sexually transmitted infection. the probable co-factors that prevent spontaneous clearance of hpv and progression to neoplasia are genital tract infections from organisms like chlamydia, trichomonas vaginalis etc, smoking, nutritional deficiencies and multiparity. inflammatory conditions can lead to pre-neoplastic manifestations in the cervical epithelium; however their specifi ... | 2016 | 27042571 |
| [in vitro susceptibility of trichomonas vaginalis to metronidazole, ornidazole and proton pump inhibitors pantoprazole and esomeprazole]. | the current treatment of trichomoniasis is based on the use of 5-nitroimidazole derivatives. although metronidazole is reliable, inexpensive and highly effective against anaerobic microorganisms and protozoa, the development of metronidazole-resistant t.vaginalis strains pose to an increasing problem. nitroimidazoles are compounds having azomycin (2-nitroimidazole) chemical structure and are obtained from streptomyces strains. benzimidazole, which is found in the structure of proton pump inhibit ... | 2016 | 27058337 |
| are the fatty acids responsible for the higher effect of oil and alcoholic extract of nigella sativa over its aqueous extract on trichomonas vaginalis trophozoites? | trichomoniasis, the disease caused by the flagellate protozoan trichomonas vaginalis is the sexually transmitted infection with the largest annual incidence. metronidazole is the drug of choice recommended for the treatment of human trichomoniasis but it can lead to drug resistance and many other adverse effects. so, it is necessary for new alternatives for the treatment of this infection. medicinal plants or herbs could be good alternative regimens to be inexpensive, effective and safe to use. ... | 2016 | 27065592 |
| evaluation of the in vitro activity of ceragenins against trichomonas vaginalis. | trichomonosis, caused by the protozoan parasite trichomonas vaginalis, is a curable sexually transmitted disease that is most commonly encountered worldwide. increasing importance of trichomoniasis and emerging of resistance against metronidazole lead to search for alternative drugs with different mode of activity. the purpose of this study was to determine in vitro activity of ceragenins (csa-13, csa-44, csa-13, and csa-138) against the metronidazole-susceptible (atcc 30001) and metronidazole-r ... | 2016 | 27078662 |
| role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-edged microbicidal spermicide: design, synthesis and biology. | trichomoniasis and candidiasis are amongst the most common morbidity-causing reproductive tract infections, generally treated by metronidazole and fluconazole respectively. poor vaginal efficacy, drug-resistance and non-spermicidal nature limit their use as topical microbicidal contraceptives. bis(dialkylaminethiocarbonyl)disulfides (4-38) were designed as dually active, non-surfactant molecules capable of eliminating trichomonas vaginalis and candida strains as well as irreversibly immobilizing ... | 2016 | 27084496 |
| a prospective study of trichomonas vaginalis and prostate cancer risk among african american men. | african americans (aa) have a higher prevalence of trichomonas vaginalis (tv) infection and a higher prostate (pc) risk. past studies suggest an association between tv seropositivity and pc, and therefore we prospectively investigated this association among aa men. | 2016 | 27091219 |
| in vitro susceptibility of iranian isolates of trichomonas vaginalis to metronidazole. | metronidazole, a 5-nitroimidazole derivative, is the main antitrichomonal agent of choice for treatment of trichomoniasis. since 1962, some cases of treatment failure with metronidazole have been reported and recently drug resistance is now on the rise in the world. this study was aimed to determine current susceptibility of iranian isolates of trichomonas vaginalis to metronidazole. | 2017 | 27095968 |
| structural investigation and inhibitory response of halide on phosphoserine aminotransferase from trichomonas vaginalis. | phosphoserine aminotransferase (psat) catalyses the second reversible step of the phosphoserine biosynthetic pathway in trichomonas vaginalis, which is crucial for the synthesis of serine and cysteine. | 2016 | 27102280 |
| screening for abnormal vaginal microflora by self-assessed vaginal ph does not enable detection of sexually transmitted infections in ugandan women. | is self-assessed vaginal ph measurement to detect abnormal vaginal bacterial microflora (avf) an adequate prescreening method for detection of genital sexually transmitted infections (stis)? | 2016 | 27112831 |
| acceptability and feasibility of sexually transmitted infection testing and treatment among pregnant women in gaborone, botswana, 2015. | chlamydia trachomatis (ct), neisseria gonorrhoeae (ng), and trichomonas vaginalis (tv) are curable sexually transmitted infections (stis) that can cause adverse maternal and birth outcomes. most countries do not conduct routine testing during antenatal care. we present data on the acceptability and feasibility of testing and treating pregnant women for stis in an antenatal clinic in gaborone, botswana. | 2016 | 27119076 |
| trichomonas vaginalis repair of iron centres proteins: the different role of two paralogs. | trichomonas vaginalis, the causative parasite of one of the most prevalent sexually transmitted diseases is, so far, the only protozoan encoding two putative repair of iron centres (ric) proteins. homologs of these proteins have been shown to protect bacteria from the chemical stress imposed by mammalian immunity. in this work, the biochemical and functional characterisation of the t. vaginalis rics revealed that the two proteins have different properties. expression of ric1 is induced by nitros ... | 2016 | 27124376 |
| comparative analysis of syndromic and pcr-based diagnostic assay reveals misdiagnosis/ overtreatment for trichomoniasis based on subjective judgment in symptomatic patients. | trichomoniasis, a sexually transmitted disease (std), is caused by trichomonas vaginalis in both men and women. screening of trichomoniasis is problematic in resource challenged settings as currently available, inexpensive diagnostic methods are of low sensitivity and/or specificity. in india, national aids control organization (naco) recommended syndromic case management (scm) for treatment. the objective of the present study was to compare the utility of the naco-nacp iii algorithms for sti/rt ... | 2016 | 27146362 |
| 2016 european guideline on the management of non-gonococcal urethritis. | we present the updated international union against sexually transmitted infections (iusti) guideline for the management of non-gonococcal urethritis in men. this guideline recommends confirmation of urethritis in symptomatic men before starting treatment. it does not recommend testing asymptomatic men for the presence of urethritis. all men with urethritis should be tested for chlamydia trachomatis and neisseria gonorrhoeae and ideally mycoplasma genitalium using a nucleic acid amplification tes ... | 2016 | 27147267 |
| trichomonas vaginalis ntpdase and ecto-5'-nucleotidase hydrolyze guanine nucleotides and increase extracellular guanosine levels under serum restriction. | trichomonas vaginalis is the aethiologic agent of trichomoniasis, the most common non-viral sexually transmitted disease in the world. the purinergic signaling pathway is mediated by extracellular nucleotides and nucleosides that are involved in many biological effects as neurotransmission, immunomodulation and inflammation. extracellular nucleotides can be hydrolyzed by a family of enzymes known as ectonucleotidases including the ecto-nucleoside triphosphate diphosphohydrolases (e-ntpdases) fam ... | 2016 | 27150347 |
| detecting asymptomatic trichomonas vaginalis in females using the bd probetec™ trichomonas vaginalis q(x) nucleic acid amplification test. | trichomonas vaginalis (tv) rates in women are increasing and many are asymptomatic. nucleic acid amplification tests (naats) are becoming the 'gold standard' for diagnosis. we aimed to establish our asymptomatic tv rates by testing all women attending oxfordshire's sexual health service, regardless of symptoms, using the bd probetec™ tv q(x) naats (bdq(x)). during bdq(x)'s verification process, the sensitivity and specificity were calculated using results of 220 endocervical samples from symptom ... | 2017 | 27150360 |
| [detection of echinococcus granulosus and echinococcus multilocularis in cyst samples using a novel single tube multiplex real-time polymerase chain reaction]. | cystic echinococcosis (ce) and alveolar echinococcosis (ae) caused by echinococcus granulosus and echinococcus multilocularis, respectively, are important helminthic diseases worldwide as well as in our country. epidemiological studies conducted in turkey showed that the prevalence of ce is 291-585/100.000. it has also been showed that the seroprevalence of ae is 3.5%. for the diagnosis of ce and ae, radiological (ultrasonography, computed tomography, magnetic resonance) and serological methods, ... | 2016 | 27175499 |
| inflammatory responses in a benign prostatic hyperplasia epithelial cell line (bph-1) infected with trichomonas vaginalis. | trichomonas vaginalis causes the most prevalent sexually transmitted infection worldwide. trichomonads have been detected in prostatic tissues from prostatitis, benign prostatic hyperplasia (bph), and prostate cancer. chronic prostatic inflammation is known as a risk factor for prostate enlargement, benign prostatic hyperplasia symptoms, and acute urinary retention. our aim was to investigate whether t. vaginalis could induce inflammatory responses in cells of a benign prostatic hyperplasia epit ... | 2016 | 27180569 |
| prevalence of trichomoniasis by pcr in women attending health screening in korea. | trichomoniasis is the most common curable sexually-transmitted infection (sti) worldwide. there are few reports on the prevalence of trichomonas vaginalis in korea. the purpose of this study was to examine the prevalence of trichomoniasis by pcr in guri city, korea. all adult women who visited hanyang university guri hospital for health screening within the national health care service were invited to participate in the study, and 424 women were enrolled between march and june 2011. pcr was used ... | 2016 | 27180577 |
| optimization of trichomonas vaginalis diagnosis during pregnancy at a university hospital, argentina. | the aim of this study was to evaluate different methods for trichomonas vaginalis diagnosis during pregnancy in order to prevent maternal and perinatal complications. a total of 386 vaginal exudates from pregnant women were analyzed. t. vaginalis was investigated by 3 types of microscopic examinations direct wet mount with physiologic saline solution, prolonged may-grunwald giemsa (mgg) staining, and wet mount with sodium-acetate-formalin (saf)/methylene blue method. pcr for 18s rrna gene as wel ... | 2016 | 27180578 |
| rapid diagnosis of trichomonas vaginalis by testing vaginal swabs in an isothermal helicase-dependent amplivue assay. | the amplivue trichomonas assay (quidel) is a new federal drug administration-cleared rapid test for qualitative detection of trichomonas vaginalis (tv) dna in female vaginal specimens. the assay is based on biohelix's helicase-dependent amplification isothermal technology in conjunction with a disposable lateral-flow detection device, with a total turnaround time of approximately 45 minutes. | 2016 | 27196258 |
| nitroimidazole carboxamides as antiparasitic agents targeting giardia lamblia, entamoeba histolytica and trichomonas vaginalis. | diarrhoeal diseases caused by the intestinal parasites giardia lamblia and entamoeba histolytica constitute a major global health burden. nitroimidazoles are first-line drugs for the treatment of giardiasis and amebiasis, with metronidazole 1 being the most commonly used drug worldwide. however, treatment failures in giardiasis occur in up to 20% of cases and development of resistance to metronidazole is of concern. we have re-examined 'old' nitroimidazoles as a foundation for the systematic dev ... | 2016 | 27236016 |
| chronic cervicitis: presenting features and response to therapy. | chronic nongonococcal nonchlamydial cervicitis is a condition of unknown etiology. data about treatment options are limited. our goal was to review a single center's experience in managing women with chronic ngncc. | 2016 | 27243142 |
| prevalence and risk factors of chlamydia trachomatis, neisseria gonorrhoeae, trichomonas vaginalis and other sexually transmissible infections among women attending antenatal clinics in three provinces in papua new guinea: a cross-sectional survey. | background: papua new guinea (png) is estimated to have among the highest prevalences of hiv and sexually transmissible infections (stis) of any asia-pacific country, and one of the highest burdens of maternal syphilis globally. the prevalence of curable stis, such as chlamydia trachomatis (ct), neisseria gonorrhoeae (ng) and trichomonas vaginalis (tv), among pregnant women in png is relatively unknown. methods: a cross-sectional bio-behavioural survey to investigate the epidemiology of ct, ng, ... | 2016 | 27248708 |
| loop-mediated isothermal amplification (lamp) assay for the rapid detection of the sexually-transmitted parasite, trichomonas vaginalis. | a loop-mediated isothermal amplification (lamp) assay was developed to detect the sexually-transmitted parasite, trichomonas vaginalis in vaginal swabs. the presence of t. vaginalis was detected from 121 female sex workers attending a social hygiene clinic in balibago, angeles city, pampanga, philippines using culture, polymerase chain reaction (pcr), and the developed lamp assay. the high analytical sensitivity of lamp detected a higher prevalence of t. vaginalis (42.06%) compared to culture (8 ... | 2016 | 27262954 |
| a novel point-of-care testing strategy for sexually transmitted infections among pregnant women in high-burden settings: results of a feasibility study in papua new guinea. | sexually transmitted and genital infections in pregnancy are associated with an increased risk of adverse maternal and neonatal health outcomes. high prevalences of sexually transmitted infections have been identified among antenatal attenders in papua new guinea. papua new guinea has amongst the highest neonatal mortality rates worldwide, with preterm birth and low birth weight major contributors to neonatal mortality. the overall aim of our study was to determine if a novel point-of-care testi ... | 2016 | 27268218 |
| evaluation of presto(plus) assay and lightmix kit trichomonas vaginalis assay for detection of trichomonas vaginalis in dry vaginal swabs. | this is an evaluation study of the presto(plus) assay for t. vaginalis by comparing to the tib molbiol lightmix kit trichomonas vaginalis assay using 615 dry collected vaginal and rectal swabs. discordant samples were analyzed by the qiagen® microbial dna qpcr for tv assay. both assays showed comparable performances (mcnemar p>0.05). | 2016 | 27268968 |
| in response to 'successful treatment of refractory trichomonas vaginalis infection using intravenous metronidazole' by hawkins et al. | 2016 | 27278450 | |
| novel hydrogenosomes in the microaerophilic jakobid stygiella incarcerata. | mitochondrion-related organelles (mros) have arisen independently in a wide range of anaerobic protist lineages. only a few of these organelles and their functions have been investigated in detail, and most of what is known about mros comes from studies of parasitic organisms such as the parabasalid trichomonas vaginalis here, we describe the mro of a free-living anaerobic jakobid excavate, stygiella incarcerata we report an rnaseq-based reconstruction of s. incarcerata's mro proteome, with an a ... | 2016 | 27280585 |
| maldi-tof mass spectrometry as a potential tool for trichomonas vaginalis identification. | trichomonas vaginalis is a flagellated protozoan causing trichomoniasis, a sexually transmitted human infection, with around 276.4 million new cases estimated by world health organization. culture is the gold standard method for the diagnosis of t. vaginalis infection. recently, immunochromatographic assays as well as pcr assays for the detection of t. vaginalis antigen or dna, respectively, have been also available. although the well-known genome sequence of t. vaginalis has made possible the a ... | 2016 | 27282151 |
| mycoplasma genitalium prevalence, coinfection, and macrolide antibiotic resistance frequency in a multicenter clinical study cohort in the united states. | the prevalence rates of mycoplasma genitalium infections and coinfections with other sexually transmitted organisms and the frequency of a macrolide antibiotic resistance phenotype were determined in urogenital specimens collected from female and male subjects enrolled in a multicenter clinical study in the united states. specimens from 946 subjects seeking care from seven geographically diverse clinical sites were tested for m. genitalium and for chlamydia trachomatis, neisseria gonorrhoeae, an ... | 2016 | 27307460 |
| a systematic review of point of care testing for chlamydia trachomatis, neisseria gonorrhoeae, and trichomonas vaginalis. | objectives. systematic review of point of care (poc) diagnostic tests for sexually transmitted infections: chlamydia trachomatis (ct), neisseria gonorrhoeae (ng), and trichomonas vaginalis (tv). methods. literature search on pubmed for articles from january 2010 to august 2015, including original research in english on poc diagnostics for sexually transmitted ct, ng, and/or tv. results. we identified 33 publications with original research on poc diagnostics for ct, ng, and/or tv. thirteen articl ... | 2016 | 27313440 |
| molecular characterization of double-stranded rna virus in trichomonas vaginalis egyptian isolates and its association with pathogenicity. | trichomoniasis is a common human sexually transmitted infection caused by trichomonas vaginalis. the parasite can be infected with double-stranded rna viruses (tvv). this viral infection may have important implications on trichomonal virulence and disease pathogenesis. this study aimed to determine the prevalence of t. vaginalis virus among isolates obtained from infected (symptomatic and asymptomatic) women in ismailia city, egypt, and to correlate the virus-infected isolates with the clinical ... | 2016 | 27316695 |
| a molecular-beacon-based asymmetric pcr assay for easy visualization of amplicons in the diagnosis of trichomoniasis. | the currently available nucleic acid amplification tests (naats) for trichomoniasis are accurate, quick and confirmative with superior sensitivity than traditional culture-based microbiology assays. however, these assays are associated with problems of carry over contamination, false positive results, requirement of technical expertise for performance and detection of end product. hence, a diagnostic assay with easy visualization of the amplified product will be profitable. an in-house, rapid, s ... | 2016 | 27318568 |
| prevalence of curable sexually transmitted infections in pregnant women in low- and middle-income countries from 2010 to 2015: a systematic review. | current literature comparing the prevalence rates of curable sexually transmitted infections (stis) in pregnant women in various global regions is limited. as a result, antenatal screening practices for curable stis in pregnant women, specifically treponema pallidum (syphilis), neisseria gonorrhoeae (ng), chlamydia trachomatis (ct), and trichomonas vaginalis (tv) vary around the world, differing by country and particular sti. | 2016 | 27322048 |
| comparative protein structure modeling using modeller. | comparative protein structure modeling predicts the three-dimensional structure of a given protein sequence (target) based primarily on its alignment to one or more proteins of known structure (templates). the prediction process consists of fold assignment, target-template alignment, model building, and model evaluation. this unit describes how to calculate comparative models using the program modeller and how to use the modbase database of such models, and discusses all four steps of comparativ ... | 2016 | 27322406 |
| proliferation of prostate stromal cell induced by benign prostatic hyperplasia epithelial cell stimulated with trichomonas vaginalis via crosstalk with mast cell. | chronic inflammation has a role in the pathogenesis of benign prostatic hyperplasia (bph) and prostate cancer. mast cells have been detected in chronic inflammatory infiltrate of the prostate, and it is possible that the interaction between prostate epithelial cells and trichomonas vaginalis influences the activity of mast cells in the prostate stroma. activated mast cells might influence the biological functions of nearby tissues and cells. in this study, we investigated whether mast cells reac ... | 2016 | 27325623 |
| aggregation kinetic dataset to determine the stability of the purified and refolded recombinant pptvcp4 protein of trichomonas vaginalis. | the recombinant pptvcp4 (pptvcp4r) protein, a specific inhibitor of the proteolytic activity and virulence properties of trichomonas vaginalis, depending on cathepsin l-like cysteine proteinases (cps) (http:dx.doi.org/ 10.1016/j.biocel.2014.12.001[1], http:dx.doi.org/ 10.1016/j.micinf.2013.09.002[2], http:dx.doi.org/ 10.1155/2015/946787[3]) was stable in the elution buffer up to two months at 4 °c. however, it was prone to aggregate in pbs (functional assay buffer) [1]. therefore, before functio ... | 2016 | 27331109 |
| morphological changes of trichomonas vaginalis treated by ornidazole: an in-vitro study. | nitroimidazoles, which are drugs that are used to effectively treat trichomonas vaginalis, alter the structure of the t. vaginalis cell membrane, penetrate into its cytoplasm and nucleus and block cellular metabolism. in this study, we observed the morphological changes that occurred in t. vaginalis during in vitro exposure to 1.3 μg/ml of ornidazole at various time intervals ranging from 10 minutes to 10 hours. | 2016 | 27349003 |
| evaluation of syndromic management guidelines for treatment of sexually transmitted infections in south african women. | to evaluate the performance of three different guidelines for the management of vaginal discharge syndrome (vds) for women living in a rural setting in south africa. | 2016 | 27350659 |
| molecular sensitivity threshold of wet mount and an immunochromatographic assay evaluated by quantitative real-time pcr for diagnosis of trichomonas vaginalis infection in a low-risk population of childbearing women. | vaginal trichomoniasis is a sexually transmitted infection caused by trichomonas vaginalis, a flagellated protozoan. diagnosis of t. vaginalis infection is mainly performed by wet mount microscopy, with a sensitivity ranging from 38% to 82%, compared to culture, still considered the gold standard. commercial immunochromatographic tests for monoclonal-antibody-based detection have been introduced as alternative methods for diagnosis of t. vaginalis infection and have been reported in some studies ... | 2016 | 27367320 |
| analysis of the vaginal microbiome by next-generation sequencing and evaluation of its performance as a clinical diagnostic tool in vaginitis. | next-generation sequencing (ngs) can detect many more microorganisms of a microbiome than traditional methods. this study aimed to analyze the vaginal microbiomes of korean women by using ngs that included bacteria and other microorganisms. the ngs results were compared with the results of other assays, and ngs was evaluated for its feasibility for predicting vaginitis. | 2016 | 27374709 |
| symbiotic association with mycoplasma hominis can influence growth rate, atp production, cytolysis and inflammatory response of trichomonas vaginalis. | the symbiosis between the parasitic protist trichomonas vaginalis and the opportunistic bacterium mycoplasma hominis is the only one currently described involving two obligate human mucosal symbionts with pathogenic capabilities that can cause independent diseases in the same anatomical site: the lower urogenital tract. although several aspects of this intriguing microbial partnership have been investigated, many questions on the influence of this symbiosis on the parasite pathobiology still rem ... | 2016 | 27379081 |
| activity of pyrrolizidine alkaloids against biofilm formation and trichomonas vaginalis. | crotalaria genus belongs to the subfamily papilionoideae comprising about 600 species spread throughout tropical, neotropical and subtropical regions. in this study, seeds of crolatalaria pallida were used to the isolation of usaramine, a pyrrolizidine alkaloid. thus, pseudomonas aeruginosa and staphylococcus epidermidis were utilized as strains to test some activities of this alkaloid, such as antibiofilm and antibacterial. meanwhile, monocrotaline obtained from crotalaria retusa seeds, was use ... | 2016 | 27399809 |
| loop-mediated isothermal amplification targeting actin dna of trichomonas vaginalis. | trichomoniasis caused by trichomonas vaginalis is a common sexually transmitted disease. its association with several health problems, including preterm birth, pelvic inflammatory disease, cervical cancer, and transmission of human immunodeficiency virus, emphasizes the importance of improved access to early and accurate detection of t. vaginalis. in this study, a rapid and efficient loop-mediated isothermal amplification-based method for the detection of t. vaginalis was developed and validated ... | 2016 | 27417089 |
| trichomonas vaginalis nucleic acid amplification testing at an urban hiv clinic. | trichomonas vaginalis is the most common nonviral sexually transmitted infection. t. vaginalis nucleic acid amplification testing (naat) recently became available at the university of alabama at birmingham human immunodeficiency virus (hiv) clinic. the objective of this study was to determine the uptake of t. vaginalis naat testing among clinic providers during the first year of test availability in addition to t. vaginalis prevalence and predictors based on naat results. | 2016 | 27419815 |
| association of human papillomavirus, neisseria gonorrhoeae and chlamydia trachomatis co-infections on the risk of high-grade squamous intraepithelial cervical lesion. | the link between high-risk human papillomavirus (hr-hpv) and other sexually transmitted diseases (stds) in the risk of developing cervical cancer still unclear. thus, in this report we investigated the rates of co-infections between hpv and other important non-hpv stds in different cervical findings using a multiplex polymerase chain reaction (m-pcr) to simultaneously detect chlamydia trachomatis, neisseria gonorrhoeae, mycoplasma genitalium, trichomonas vaginalis, hsv-1 and -2, and treponema pa ... | 2016 | 27429850 |
| identification, characterization, and synthesis of peptide epitopes and a recombinant six-epitope protein for trichomonas vaginalis serodiagnosis. | there is a need for a rapid, accurate serodiagnostic test useful for both women and men infected by trichomonas vaginalis, which causes the number one sexually transmitted infection (sti). women and men exposed to t. vaginalis make serum antibody to fructose-1,6-bisphosphate aldolase (ald), α-enolase (eno), and glyceraldehyde-3-phosphate dehydrogenase (gap). we identified, by epitope mapping, the common and distinct epitopes of each protein detected by the sera of women patients with trichomonos ... | 2013 | 27471691 |
| the glycolytic enzyme triosephosphate isomerase of trichomonas vaginalis is a surface-associated protein induced by glucose that functions as a laminin- and fibronectin-binding protein. | triosephosphate isomerase of trichomonas vaginalis (tvtim) is a 27-kda cytoplasmic protein encoded by two genes, tvtim1 and tvtim2, that participates in glucose metabolism. tvtim is also localized to the parasite surface. thus, the goal of this study was to identify the novel functions of the surface-associated tvtim in t. vaginalis and to assess the effect of glucose as an environmental factor that regulates its expression and localization. reverse transcription-pcr (rt-pcr) showed that the tvt ... | 2016 | 27481251 |
| mono- and multimeric ferrocene congeners of quinoline-based polyamines as potential antiparasitics. | a series of mono- and multimeric polyamine-containing ferrocenyl complexes containing a quinoline motif were prepared. the complexes were characterised by standard techniques. the molecular structure of the monomeric salicylaldimine derivative was elucidated using single crystal x-ray diffraction and was consistent with the proposed structure. the antiplasmodial activity of the compounds were evaluated in vitro against both the nf54 (chloroquine-sensitive) and k1 (chloroquine-resistant) strains ... | 2016 | 27485032 |
| self-testing for trichomonas vaginalis at home using a point-of-care test by women who request kits via the internet. | we offered a point-of-care test for trichomonas vaginalis to women via the internet to determine if it was acceptable to women to perform the test at home. most of the 102 participants felt that it was easy to collect the specimen, follow the instructions, and read and interpret the results for the trichomonas self-testing assay. | 2016 | 27491592 |
| performance of self-collected penile-meatal swabs compared to clinician-collected urethral swabs for the detection of chlamydia trachomatis, neisseria gonorrhoeae, trichomonas vaginalis, and mycoplasma genitalium by nucleic acid amplification assays. | men were enrolled in a study to assess the performance and acceptability of self-collected penile meatal swabs as compared to clinician-collected urethral swabs for sexually transmitted infections (stis). we expected penile-meatal swabs to perform favorably to urethral swabs for chlamydia trachomatis (ct), neisseria gonorrhoeae (ng), trichomonas vaginalis (tv), and mycoplasma genitalium (mg) detection by nucleic acid amplification assays (naats). of 203 swab pairs tested; for ct, penile-meatal s ... | 2016 | 27497595 |
| purification and identification of amylases released by the human pathogen trichomonas vaginalis that are active towards glycogen. | the parasitic protist trichomonas vaginalis is the causative agent of the sexually transmitted infection trichomoniasis. in the laboratory, t. vaginalis is typically cultured in a serum-containing medium with maltose or glucose as the carbon source. the nature of the carbohydrates used by the organism in the environment of its host is unclear. however, the vagina contains substantial amounts of glycogen, which is believed to provide a growth substrate for the vaginal microbiota. we have shown pr ... | 2016 | 27506885 |
| [characteristics of vaginal ecosystem in endocervicitis chlamydialis]. | the study aims: 1. to analyze and study the specifics of microbiocenoses of exocervix at endocervicitis chlamydialis, to differentiate the spectrum of stimuli, and establish the leading role of chl. trachomatis in the genesis of this process. 2. to determine the leading role of the method of direct (bed-side) microscopy for early and rapid diagnosis of cervicitis and conducting etiotropic therapy. we determined the incidence of endocervicitis chlamydialis, with cause chl. trachomatis-45.1%, (319 ... | 2016 | 27514125 |
| corrigendum to "α-actinin tvactn3 of trichomonas vaginalis is an rna-binding protein that could participate in its posttranscriptional iron regulatory mechanism". | [this corrects the article doi: 10.1155/2014/424767.]. | 2017 | 27517042 |
| male partner circumcision associated with lower trichomonas vaginalis incidence among pregnant and postpartum kenyan women: a prospective cohort study. | trichomonas vaginalis is the world's most common curable sti and has implications for reproductive health in women. we determined incidence and correlates of t. vaginalis in an hiv-uninfected peripartum cohort. | 2017 | 27519258 |
| synthesis, screening and in silico simulations of anti-parasitic propamidine/benzimidazole derivatives. | propamidine, an antiseptic aromatic diamidine is a toxic compound with potential use as antiprotozoal drug. on the other hand, benzimidazole derivatives have shown excellent antiparasitic effects. we designed hybrid molecules between propamidine and benzimidazole in order to retain the antiprotozoal action, but decreasing the toxic effect of the molecule. objetive: design and prepare 12 hybrids from propamidine and benzimidazole for testing their antiparasitic effect over three protozoa: giardia ... | 2016 | 27527618 |
| leukocyte lysis and cytokine induction by the human sexually transmitted parasite trichomonas vaginalis. | trichomonas vaginalis (tv) is an extracellular protozoan parasite that causes the most common non-viral sexually transmitted infection: trichomoniasis. while acute symptoms in women may include vaginitis, infections are often asymptomatic, but can persist and are associated with medical complications including increased hiv susceptibility, infertility, pre-term labor, and higher incidence of cervical cancer. heightened inflammation resulting from tv infection could account for these complication ... | 2016 | 27529696 |
| a calcium sensor - protein kinase signaling module diversified in plants and is retained in all lineages of bikonta species. | calcium (ca(2+)) signaling is a universal mechanism of signal transduction and involves ca(2+) signal formation and decoding of information by ca(2+) binding proteins. calcineurin b-like proteins (cbls), which upon ca(2+) binding activate cbl-interacting protein kinases (cipks) regulate a multitude of physiological processes in plants. here, we combine phylogenomics and functional analyses to investigate the occurrence and structural conservation of cbl and cipk proteins in 26 species representi ... | 2016 | 27538881 |
| signalling pathways associated with il-6 production and epithelial-mesenchymal transition induction in prostate epithelial cells stimulated with trichomonas vaginalis. | trichomonas vaginalis (tv) has been found in patient tissue of benign prostatic hyperplasia (bph), and suggested to cause chronic prostatitis. il-6 is known as one of the important factors of chronic inflammation in prostate cancer. patients with chronic prostatitis/chronic pelvic pain syndrome (cp/cpps) had higher levels of il-6 in seminal plasma. furthermore, inflammatory conditions induced by pathogen infections have been shown to promote epithelial-mesenchymal transition (emt). here, we inve ... | 2016 | 27543848 |
| multilocus sequence typing of dientamoeba fragilis identified a major clone with widespread geographical distribution. | the flagellated protozoan dientamoeba fragilis is often detected in humans with gastrointestinal symptoms, but it is also commonly found in healthy subjects. as for other intestinal protozoa, the hypothesis that genetically dissimilar parasite isolates differ in their ability to cause symptoms has also been raised for d. fragilis. to date, only two d. fragilis genotypes (1 and 2) have been described, of which genotype 1 largely predominates worldwide. however, very few markers are available for ... | 2016 | 27555056 |
| antiprotozoal screening of the cuban native plant scutellaria havanensis. | scutellaria havanensis jacq. (lamiaceae) is a native medicinal herb with a history of use in cuba. | 2016 | 27564587 |
| sexually transmitted infections other than hiv/aids among women of low socio-economic class attending antenatal clinics in khartoum, sudan. | sexually transmitted infections (stis) are major health threats affecting people globally; however, the burden of stis is greatest in low-income countries. since they are physiologically more vulnerable, women are mostly affected. the risk is increased dramatically during pregnancy leading to serious health complications that may affect the newborn. underprivileged pregnant women attending antenatal clinics for routine checkups in displaced camps, a women's prison and several peripheral health c ... | 2016 | 27582306 |
| sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in jalisco, mexico. | to determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in jalisco, mexico. | 2016 | 27599076 |
| effect of nigella sativa alcoholic extract and oil, as well as phaseolus vulgaris (kidney bean) lectin on the ultrastructure of trichomonas vaginalis trophozoites. | trichomonas vaginalis is a parasitic protozoan that is the aetiological agent of trichomoniasis, the most common non-viral sexually transmitted disease worldwide. currently, the compound of choice for the treatment of t. vaginalis infections is metronidazole, however, it has many side effects and an increase in metronidazole-resistant trichomoniasis has been observed. medicinal plants could be a source of new antiprotozoal drugs with high activity, low toxicity and lower price. the present work ... | 2016 | 27605771 |
| trichomonas vaginalis: a possible foe to prostate cancer. | prostate cancer (pca) is the most common malignancy in men in usa, and the role of trichomonas vaginalis (t. vag) in the development of pca is still controversial. clonogenic assay, pcna staining, tunel staining and caspase-3 activity assay were used to investigate the in vitro role of t. vag in human prostate cancer. we further investigated the possible molecular mechanisms using rt-pcr and immunohistochemical staining. culture supernatant of t. vag inhibits growth of pc-3 prostate cancer cells ... | 2016 | 27613161 |
| sending a message: extracellular vesicles of pathogenic protozoan parasites. | parasitic unicellular eukaryotes use extracellular vesicles (evs) as vehicles for intercellular communication and host manipulation. by using various mechanisms to generate evs and by transferring a wide range of molecules through evs, pathogenic protozoans are able to establish infective niches, modulate the immune system of the host and cause disease. in addition to effects on the host, evs are able to transfer virulence factors, drug-resistance genes and differentiation factors between parasi ... | 2016 | 27615028 |
| recruitment of minority adolescents and young adults into randomised clinical trials: testing the design of the technology enhanced community health nursing (tech-n) pelvic inflammatory disease trial. | pelvic inflammatory disease (pid) disproportionately affects adolescent and young adult (aya) women and can negatively influence reproductive health trajectories. few randomized controlled trials (rcts) have focused on strategies to improve outpatient adherence or to reduce reproductive morbidity in this population. this paper describes the research methods and preliminary effectiveness of recruitment, retention, and intervention strategies employed in a novel rct designed to test a technology-e ... | 2016 | 27617108 |
| recombinant trichomonas vaginalis eif-5a protein expressed from a eukaryotic system binds specifically to mammalian and putative trichomonal eif-5a response elements (eres). | trichomonas vaginalis eif-5a-like protein (tveif-5a) belongs to the highly conserved eif-5a family of proteins that contains a unique polyamine-derived amino acid, hypusine. recently, we determined that the polyamine putrescine is required for tveif-5a mrna stability, and it is necessary for stability and maturation of the tveif-5a protein. eukaryotic eif-5a is known to be involved in mrna turnover and is capable of sequence-specific rna binding to eif-5a response elements (eres). these ere sequ ... | 2016 | 27620329 |
| expansion of comprehensive screening of male sexually transmitted infection clinic attendees with mycoplasma genitalium and trichomonas vaginalis molecular assessment: a retrospective analysis. | of 1,493 encounters of males at a sexually transmitted infection (sti) clinic in a community with a high prevalence of sti, chlamydia trachomatis was detected in 8.7% and neisseria gonorrhoeae was detected in 6.6%. additional trichomonas vaginalis and mycoplasma genitalium screening found 17.4% and 23.9% of the encounters, respectively, to be positive for sti. sti agents were detected in 13.7% of urine specimens; addition of pharyngeal and rectal collections to the analysis resulted in detection ... | 2017 | 27629896 |
| trichomonas vaginalis and human immunodeficiency virus coinfection among women under community supervision: a call for expanded t. vaginalis screening. | the united states has a large community supervision population, a growing number of whom are women. trichomonas vaginalis infection is strongly associated with an increased risk of human immunodeficiency virus (hiv) acquisition and transmission, particularly among women, but there is a paucity of research on hiv and t. vaginalis co-infection among women under community supervision. | 2016 | 27631355 |
| diagnosis of trichomoniasis in men by urine cytology. | trichomonas vaginalis is a rare finding in urine cytology specimens, especially those from men; only 2 case reports have been described in the literature. the authors of the current report sought to determine the incidence and clinical significance of this finding in urine cytology in males. | 2017 | 27636204 |
| 2-methyl-4/5-nitroimidazole derivatives potentiated against sexually transmitted trichomonas: design, synthesis, biology and 3d-qsar study. | trichomoniasis is the most prevalent, non-viral sexually transmitted diseases (std) caused by amitochondriate protozoan trichomonas vaginalis. increased resistance of t. vaginalis to the marketed drug metronidazole necessitates the development of newer chemical entities. a library of sixty 2-methyl-4/5-nitroimidazole derivatives was synthesized via nucleophilic ring opening reaction of epoxide and the efficacies against drug-susceptible and -resistant trichomonas vaginalis were evaluated. all th ... | 2016 | 27643640 |
| reproductive tract infections and premalignant lesions of cervix: evidence from women presenting at the cancer detection centre of the indian cancer society, delhi, 2000-2012. | burden of cervical cancer (cc) is highest for women in low- and middle-income countries (lmics). human papillomavirus (hpv) is implicated as the necessary cause of cc although a number of other factors aid the long process of cc development. one among them is the presence of reproductive tract infections (rtis). this study investigated the associations between rtis and cc from india. | 2016 | 27651644 |
| detection of trichomonas vaginalis in prostate tissue and serostatus in patients with asymptomatic benign prostatic hyperplasia. | despite a worldwide common and progressive nature of benign prostate hyperplasia (bph) in older men, no association has been observed between a causative pathogen and other etiology so far. | 2016 | 27660027 |
| technical note: preservation of trichomonas vaginalis viability in urine for laboratorial diagnosis by the wet mount examination. | this study compared preservative solutions at different temperatures aiming to improve the wet mount for trichomoniasis diagnosis. the glucose-saline ph6.0 solution preserved the trophozoites up to 6h. the urine samples preservation is crucial for diagnosis and we suggest this solution as part of the clinical laboratorial routine. | 2016 | 27666653 |
| trichomonas vaginalis prevalence and risk factors for women in southern brazil. | trichomonas vaginalis infections have been associated with other diseases so that epidemiological studies of the parasite are important and help to prevent the spread of the disease. this study aimed to determine the prevalence of t. vaginalis in female patients of 19 counties in southwestern rio grande do sul, brazil. for diagnosis, was used direct examination, followed by applying a socio-epidemiological questionnaire. we analyzed 300 women and 9% were infected by trichomonas vaginalis. the hi ... | 2016 | 27680166 |
| anti-trichomonas vaginalis activity of betulinic acid derivatives. | caused by trichomonas vaginalis, trichomoniasis is the most common non-viral std worldwide. currently, metronidazole and tinidazole are the only drugs approved for treatment of the condition. however, problems such as metronidazole-resistant t. vaginalis isolates and allergic reactions have been reported. based on data previously published by our group, structural changes in betulinic acid (1) were performed, generating three new compounds that were tested for in vitro anti-t.vaginalis activity ... | 2016 | 27685791 |
| trichomonas vaginalis infection is uncommon in the british general population: implications for clinical testing and public health screening. | variable use of new molecular assays, asymptomatic infections and a lack of population data mean that the population burden of trichomonas vaginalis is uncertain. we investigated the age-specific prevalence of t. vaginalis within the sexually active british general population to inform testing strategies. | 2016 | 27686884 |
| challenges and persistent questions in treatment of trichomoniasis. | trichomoniasis is a sexually transmitted disease (std) caused by infection with the protozoan parasite trichomonas vaginalis. it is considered the most prevalent non-viral sexually transmitted disease worldwide. recently, the infection has been associated with adverse outcomes of pregnancy and increased risks of hiv acquisition and transmission, besides the association with cervical and prostate cancers. the consequences of trichomoniasis are likely much greater than previously recognized, both ... | 2016 | 27697044 |
| the performance of the vaginal discharge syndromic management in treating vaginal and cervical infection: a systematic review and meta-analysis. | this review aimed to synthesize and analyze the diagnostic accuracy and the likelihood of providing correct treatment of the syndromic approach vaginal discharge flowchart in managing cervical infections caused by neisseria gonorrhoeae (ng) and chlamydia trachomatis (ct), and vaginal infections caused by trichomonas vaginalis (tv) and bacterial vaginosis (bv) and candida albicans. this review will inform updating the who 2003 guidelines on vaginal discharge syndromic case management. | 2016 | 27706174 |
| multilocus sequence typing of trichomonas vaginalis clinical samples from amsterdam, the netherlands. | in this cross-sectional epidemiological study we aimed to identify molecular profiles for trichomonas vaginalis and to determine how these molecular profiles were related to patient demographic and clinical characteristics. | 2016 | 27737887 |
| the cytoskeleton of parabasalian parasites comprises proteins that share properties common to intermediate filament proteins. | certain protist lineages bear cytoskeletal structures that are germane to them and define their individual group. trichomonadida are excavate parasites united by a unique cytoskeletal framework, which includes tubulin-based structures such as the pelta and axostyle, but also other filaments such as the striated costa whose protein composition remains unknown. we determined the proteome of the detergent-resistant cytoskeleton of tetratrichomonas gallinarum. 203 proteins with homology to trichomon ... | 2016 | 27744090 |
| budgetary impact of compliance with sti screening guidelines in persons living with hiv. | the 2015 centers for disease control sexually transmitted diseases treatment guidelines recommend annual screening of all people living with hiv (plwh) for neisseria gonorrhoeae, chlamydia trachomatis, and syphilis; annual trichomonas vaginalis screening is recommended for hiv-infected women. the study objective was to evaluate the budgetary impact of sexually transmitted infection (sti) screening. we hypothesized that recommended sti screening is costly and would not be covered in full by insur ... | 2017 | 27787348 |
| perturbing purinergic signaling: a pathogen's guidebook to counteracting inflammatory responses. | in this issue of the biomedical journal, we learn how bacteria and parasites alike counteract inflammatory signaling by manipulating purinergic signaling. we also focus on an original article shedding light on the role of an epstein-barr virus encoded gene in metastasis in nasopharyngeal carcinoma. finally, we learn about a possible link between trichomonas vaginalis and recurrent urinary tract infection. | 2016 | 27793264 |
| trichomoniasis immunity and the involvement of the purinergic signaling. | innate and adaptive immunity play a significant role in trichomoniasis, the most common non-viral sexually transmitted disease worldwide. in the urogenital tract, innate immunity is accomplished by a defense physical barrier constituted by epithelial cells, mucus, and acidic ph. during infection, immune cells, antimicrobial peptides, cytokines, chemokines, and adaptive immunity evolve in the reproductive tract, and a proinflammatory response is generated to eliminate the invading extracellular p ... | 2016 | 27793265 |
| a pilot study on trichomonas vaginalis in women with recurrent urinary tract infections. | trichomoniasis and recurrent urinary tract infections (utis) shared similar risk factors, age distribution and overlapping symptoms. the aim of this study was to determine the prevalence of trichomonas vaginalis (tv) in women with recurrent utis, attending a urology clinic in a medical center, in order to inform screening and treatment policies. | 2016 | 27793272 |
| combined testing for chlamydia, gonorrhea, and trichomonas by use of the bd max ct/gc/tv assay with genitourinary specimen types. | the bd max ct/gc/tv (max) assay is a true multiplex assay for simultaneous detection of chlamydia (ct), gonorrhea (gc), and trichomonas (tv). we evaluated assay performance for women using endocervical and vaginal swabs as well as urine specimens. a total of 1,143 women were tested for ct, gc, and tv and, subsequently, another 847 (1,990 total women) for ct and gc only, with positivity rates for ct, gc, and tv of 7.1%, 2.3%, and 13.5%, respectively. in men, the performance for ct and gc was dete ... | 2017 | 27795343 |