Publications

effects of acetyl strophanthidin on duration of atrial fibrillation in the neurally-intact and blockaded dog.	although the inotropic and dromotropic effects of cardiac glycosides in atrial fibrillation (af) are well recognized, their action on af itself is not clear. accordingly, to determine whether cardiac glycosides prolong af, the duration of electrically induced af, atrioventricular conduction, and left ventricular function were assessed for 30 minutes before and for 30 minutes following intravenous administration of acetyl strophanthidin (as), 20 micrograms/kg, in neurally intact, beta-blocked, an ...	1988	3154634
the biochemistry of endogenous organosulphur compounds.	the role and metabolism of methionine and cysteine in mammals are described. an outline of the history of glutathione, of its function in maintaining the thiol status of the cell and of its protective action against oxidative stress, is given. the importance of glutathione reductase, glutathione peroxidases, glutathione-s-transferases in endogenous metabolism and of gamma-glutamyltranspeptidase is described. the relationship between cysteine and glutathione is considered together with the inter- ...	2011	3155361
[effectiveness of "hunmiewei" and deltamethrin residual spraying in controlling anopheles sinensis].		2009	3155383
[effectiveness of "hunmiewei" and deltamethrin residual spraying in controlling anopheles sinensis].		2009	3155383
preliminary characterization of a soluble immunosuppressive molecule from dba/2 spleen cells using monoclonal antibody immunoadsorbence.	in a previous publication a monoclonal antibody (b16g) which appeared to recognize t suppressor cells and a t-suppressor factor (tsf) in the spleens of dba/2 mice was described. b16g appears to be directed to a public specificity of dba/2 tsf and therefore has been shown to inhibit a variety of immunological reactions. the present study involves preliminary characterization of the material with which b16g reacts. it was found that the b16g-reactive protein (putative tsf) could be absorbed and el ...	2011	3155655
[a new serotype of shigella flexneri in czechoslovakia?].		1985	3155665
synthesis of new polyoxin derivatives and their activity against chitin synthase from candida albicans.	two analogues of l-alanylpolyoxin c with a modified peptide bond were synthesized and tested for inhibition of chitin synthase in candida albicans. n-methylation of the peptide bond (compound 13) or the replacement of it by nh2ch2 (compound 9) led to loss of activity in the enzyme assay. a novel analogue (compound 5) of nikkomycin was synthesized from uracil polyoxin c and (2s,3r)-3-hydroxyhomotyrosine, a component of echinocandin c. despite high activity in the chitin synthase assay, 5 had no i ...	1985	3156247
distribution of sensory receptors in the flexor carpi radialis muscle of the cat.	the structures and distribution of encapsulated muscle receptors were examined in serial transverse sections of flexor carpi radialis in the adult cat. four types of receptors (muscle spindles, golgi tendon organs, paciniform, and pacinian corpuscles) were identified. their structures resembled those encountered in other limb muscles. pacinian corpuscles were rare and occurred only in the external fascial coat of the muscle near its origin. the other three receptor types were distributed in an u ...	1985	3156250
[open approach to the subclavian vein for permanent cardiac stimulation].	in 97.5% of 562 successive attempts, puncture of the subclavian vein to introduce permanent pacemaker electrodes was made easier and safer by the incisional technique described in this report. the very low incidence (0.35%) of traumatic pneumothorax and the absence, after a long follow-up, of any infection or exteriorization of the pacemaker chamber were the main advantages of this technical variant.	2011	3156361
expression of laminin receptor in normal and carcinomatous human tissues as defined by a monoclonal antibody.	it has been hypothesized that epithelial and endothelial cells interact with the laminin component of basement membranes via a cell surface laminin receptor molecule. it has also been proposed that the expression of this molecule may be involved in the invasion of carcinoma cells from their tissue of origin and their subsequent penetration through blood vessel basement membranes. we report here the use of a monoclonal antibody, lr-3, to define the expression of laminin receptor in normal, dyspla ...	1985	3157447
[transdermal clonidine: a new therapeutic approach in essential hypertension?].		2011	3158058
antithrombin iii, plasminogen, plasmin, and alpha-2-antiplasmin in donor blood and plasma components.	the functional levels of antithrombin iii, plasminogen, plasmin, and alpha-2-antiplasmin were evaluated in sequentially derived fresh frozen plasma, cryoprecipitate, and cryo-poor plasma aliquots from 20 registered blood donors. antithrombin iii is the major plasma inhibitor of the serine proteases of the procoagulant system. plasminogen, the proenzymatic form of plasmin, is the primary endogenous profibrinolytic moiety; alpha-2-antiplasmin is the principal intermediate acting inhibitor of plasm ...	2011	3158265
[50th anniversary of the department of neuropathology and neurosurgery of vitebsk medical school].		2011	3159172
characterization of protein kinase c and its role in catecholamine secretion from bovine adrenal-medullary cells.	protein kinase c activity towards exogenous histone was detected in a cytosolic fraction of bovine adrenal medulla. the enzyme was dependent on ca2+ and phosphatidylserine for its activity, with half-maximal activation being achieved at approx. 18 microm free ca2+ and 8 micrograms of phosphatidylserine/ml. both diolein and 4 beta-phorbol 12-myristate 13-acetate (tpa) decreased the ca2+ requirement of the enzyme, half-maximal activation being obtained at approx. 12 microm and 9 microm free ca2+ r ...	1985	3159383
synthesis of aerobactin and a 76,000-dalton iron-regulated outer membrane protein by escherichia coli k-12-shigella flexneri hybrids and by enteroinvasive strains of escherichia coli.	one of the chromosomal segments associated with the virulence of shigella flexneri and transferred to escherichia coli k-12 by conjugation has been shown to code for the production of aerobactin and for the synthesis of an iron-regulated 76,000-dalton (76k) outer membrane protein. analysis of various e. coli k-12-s. flexneri transconjugants showed that the genes involved with the synthesis of aerobactin and with the production of the 76k protein were linked to the mtl region of the s. flexneri c ...	1985	3159680
chordoma in a chronic pain patient.	a 60-year-old woman was admitted to the hospital with a recurrence of low back pain. she was begun on a behavior modification pain control program. follow-up x-rays, including ct scan of the lumbosacral spine, showed a large tumor of the l3 vertebra. she subsequently underwent surgical resection of a large chordoma of the l3 vertebra and had good resolution of her back pain.	2011	3160321
metabolism of thymoxamine. i. studies with 14c-thymoxamine in rats.	thymoxamine is rapidly and completely absorbed in rats. it is a prodrug which does not enter the systemic circulation in its unchanged form. after either oral or intravenous administration it undergoes rapid and intense metabolism involving four biotransformation reactions: enzymatic hydrolysis to the corresponding phenol (metabolite i), monodemethylation to metabolite ii, sulfate conjugation of i and ii (metabolites iii and iv) and conjugation of i and ii with glucuronic acid (metabolites v and ...	1985	3161738
receptive language processing and ear advantage of down's syndrome children.	a group of down's syndrome (ds) children was tested on part 5 of the token test for children (ttc) and a dichotic listening test (dlt, digits), and their scores were compared with those of a group of retarded children with other conditions (non-ds), matched on ppvt score and ca. it was found that the ds children showed significantly more of a left ear advantage on the dlt than did the non-ds group, and also performed significantly more poorly than the non-ds children on those tasks requiring an ...	2011	3162031
luteolytic potency of 16-phenoxy-derivatives of prostaglandin f2 alpha.	the binding of 16-phenoxy derivatives of prostaglandin (pg) f2 alpha to rat luteal membranes, and also their abortifacient potency in pregnant rats, have been studied. competitive binding studies with various pg-analogues were performed in ovaries of juvenile rats pretreated with pmsg and hcg, and in parallel studies the abortifacient potency of these substances was tested in pregnant rats. it was observed that this class of derivatives bound to the pgf2 alpha receptor as well as, or even better ...	1988	3162421
dosimetry for radiolabelled antibodies--macro or micro?	three approaches to calculating radiation absorbed doses and answering fundamental questions in radiolabelled antibody therapy are outlined. conventional macroscopic dosimetry is probably not appropriate for calculations on the small scale of normal tissue and tumour volumes that are of interest in therapy. a better though even more traditional approach is to use the results from beta particle dosimetry. these may be shown to apply down to quite small populations of cells. an approach using the ...	2011	3162447
surface charge of macrophages and their interaction with charged particles.	the distribution and concentration of surface ionogenic groups on murine peritoneal macrophages and the responses of their plasmalemma to charged markers were investigated by electron microscopy. quantitation of the distribution of cationized ferritin (cf) as a marker for anionic groups on fixed cells revealed surface anions on invaginated parts of the plasmalemma to be fewer than those on flat or projecting segments. cationic groups on the surface membrane, however, could not be labeled with an ...	2011	3164749
[a new method for measuring tooth mobility].		2011	3165431
difficult denture birds--new sightings.	a unique insight into characteristics, motivation, and behavior of problem complete denture patients is colorfully presented.	2011	3165462
[pharmacokinetics of cefotiam in patients undergoing continuous ambulatory peritoneal dialysis].	the pharmacokinetics of cefotiam (ctm) was investigated in 7 patients undergoing continuous ambulatory peritoneal dialysis (capd). one gram of ctm was infused either intravenously (i.v. group) or intraperitoneally (i.p. group). in the i.v. group, the serum concentration of ctm at 6 hours after infusion was 25.9 mg/l and the half-life value was 5.09 hours, while the peak value of ctm in dialysate was 12.4 mg/l. in the i.p. group without peritonitis, the dialysate concentration of ctm at 6 hours a ...	2011	3165474
hematologic status in recurrent aphthous stomatitis compared with other oral disease.	the hematologic status of 144 consecutive patients in the united kingdom with oral disease (69 with recurrent aphthous stomatitis; 75 with other disorders) was examined in an attempt to resolve the controversy as to whether levels of hemoglobin, blood cell numbers and indices, and blood film are adequate in the screening of patients with aphthae. though hemoglobin levels and red blood cell indices were normal in patients with recurrent aphthous stomatitis, there was still a small minority of pat ...	2011	3165514
an unusual ventilator valve failure.		2011	3165607
third molar eruption in a 12-year-old girl.		2011	3165662
[individual, reproducible temporomandibular joint radiograph].		2011	3166299
transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells.	we have explored the hypothesis that hypertrophy of vascular smooth muscle cells may be regulated, in part, by growth inhibitory factors that alter the pattern of the growth response to serum mitogens by characterizing the effects of the potent growth inhibitor, transforming growth factor-beta (tgf-beta), on both hyperplastic and hypertrophic growth of cultured rat aortic smooth muscle cells. tgf-beta inhibited serum-induced proliferation of rat aortic smooth muscle cells (ed50 = 2 pm); this is ...	1988	3166463
a correlation between regional acetylcholinesterase activity in rat brain and performance in a spatial task.	the acquisition and retention of a water maze task was examined in 12 intact, young wistar rats. acetylcholinesterase activity in 43 discrete brain regions was then measured in the same rats by quantitative histochemistry. individual learning and retention indices were found to be significantly correlated with acetylcholinesterase (ache) levels in specific regions, e.g. cholinergic nuclei; the ventral pallidum and nucleus basalis; and in the dentate gyrus of the hippocampus. high levels of ache ...	1988	3166718
changes in vascular reactivity in experimental diabetic rats: comparison with hypothyroid rats.	the responsiveness to vasoactive agents in the perfused mesenteric vascular bed of streptozocin-induced diabetic rats was examined and compared with that of propylthiouracil-induced hypothyroid rats. diabetic rats at 4 and 8 weeks after the induction of diabetes showed a significant decrease in isoproterenol-induced vasodilatation. in addition, the contractile responses to norepinephrine and 5-hydroxytryptamine and the vasodilative response to acetylcholine were significantly decreased in 12-wee ...	1988	3167224
the need to compare the effectiveness of antidepressant drugs: in which patient populations?		2011	3167485
production of tumor necrosis factor in nude mice by muramyl peptides associated with bacterial vaccines.	gram-negative vaccines can elicit the production of tumor necrosis factor (tnf) in mice primed by muramyl dipeptide (mdp) or by its lipophilic derivative mdp-dipalmitoyl glycerol (mdp-gdp). in mice pretreated with mdp and particularly with mdp-gdp, bordetella pertussis vaccine was shown to be more effective than typhoid vaccine. the time course of tnf production in the blood did not indicate any difference between the effect of mdp or of mdp-gdp. in both cases the cytotoxic activity reached maxi ...	1988	3167834
[motility of spermatozoa and its significance for fertilization in vivo and in vitro].		2011	3169626
production of human-human hybridomas secreting monoclonal antibodies reactive to breast cancer cell lines.	we produced human-human hybridomas by fusing lymph node lymphocytes of breast cancer patients with a fusion partner, ho-323 cells, in the presence of 50% polyethylene glycol, and screened hybridomas producing monoclonal antibody (moab) reactive to a breast cancer cell line, mcf-7. among 11 hybridomas secreting igm reactive to mcf-7, four hybridomas (h15a3, h15f2, k15b4, and k15c3) produced igm reacting specifically to breast cancer cell lines (mcf-7 and hbc-5). among them, h15a3 proliferated in ...	1988	3170451
nonossifying fibroma of the fibula with open section defect.		2011	3171962
telescoping in dating naturally occurring events.		2011	3173095
[hepatic angiosarcoma caused by vinyl chloride: a new italian case].		2011	3173219
effect of vagotomy on bile acid absorption by rat small intestine in vitro.		1988	3175250
multiple cysteine proteinase forms during the life cycle of dictyostelium discoideum revealed by electrophoretic analysis.	proteinases of the cellular slime mould dictyostelium discoideum have been analysed using electrophoresis on polyacrylamide gels containing gelatin (gelatin/page). multiple proteinase forms were apparent in vegetative myxamoebae, but the presence of individual enzyme forms depended on the manner in which the cells were grown. axenic cells had a characteristic a-pattern of proteinases consisting of six bands, the most active enzymes having apparent mr values of 51,000 and 45,000 (these have been ...	1988	3178750
[dubowitz syndrome. presentation of a case].		2010	3178992
[disorders of the hypothalamo-hypophyseal-gonadal axis and erectile impotence].		2011	3181023
inst-risk ii: an approach to forecasting relative risk of future institutional placement.	this article describes a model development process that represents a useful step in classifying populations in terms of risk of institutionalization (inst-risk ii). a four-category risk classification system--"high risk, some risk, low risk, and very low risk"--was developed, based on combinations of measures of functional status, age, health status, demographics, and social supports. our review of variables found by other researchers to be related to high risk of institutional placement, as wel ...	2011	3182290
activity of glucosidase inhibitors against hiv infections.		1988	3182426
total knee arthroplasty for tuberculous arthritis.	nineteen patients (twenty-two knees) who had tuberculous arthritis of the knee had a total knee arthroplasty. the interval between the subsidence of signs of infection and the arthroplasty ranged from three months to five years, and the period of follow-up ranged from twenty-four to forty-nine months. culture of fluid that had been aspirated from the joint preoperatively and culture of a biopsy specimen were negative. biopsies of specimens of synovial material revealed tuberculous granuloma in a ...	2011	3182885
phrenic nerve paralysis following pediatric cardiac surgery. role of diaphragmatic plication.	eighteen children sustained unilateral phrenic nerve paralysis (pnp) after cardiac surgical procedures. ten (group i), under 7 months (mean: 2.9 +/- 2.2), required long-term ventilatory assistance (mean: 23.9 +/- 13.0 days); they failed to be weaned from the ventilator. all underwent diaphragmatic plication (dp). dp was performed late in 7 cases (group ia) with a mean time of 30.8 days between surgery and dp, and early in 3 others (group ib) with a mean time of 10.2 days. eight children (group i ...	2011	3182930
molecular studies of hhv-6.	methods for the purification of enveloped hhv-6 virions and the viral dna are presented. the viral genome is estimated to be 170,000 base pairs in size and does not appear to contain inversions due to absence of submolar bands by restriction enzyme analyses. the genomes of two independent hhv-6 isolates, hhv-6gs and hhv-6z29, showed restriction enzyme site pleomorphism. large scale purification of enveloped hhv-6 was achieved by continuous flow centrifugation utilizing sucrose gradients, dnase 1 ...	2011	3182953
heterogeneous colony forming ability in vitro of the abnormal clone-derived granulocyte-macrophage precursors in myelodysplastic syndromes.	the clonal origin of granulocyte-macrophage colony forming cells (cfu-gm) in the myelodysplastic syndrome (mds) was cytogenetically studied. chromosome analysis was carried out on single gm-colonies from six patients with mds, whose bone marrow cells had chromosome abnormalities. abnormal clone-derived cfu-gm were grown in four patients under the presence of human placental conditioned medium. in the remaining two, all analysed colonies revealed a normal karyotype, although the majority of metap ...	1988	3184986
measurement of local cerebral glucose utilization before and after v-p shunt in congenital hydrocephalus in rats.	local cerebral glucose utilization (lcgu) was measured by the [14c]deoxyglucose autoradiographic method in rats with congenital hydrocephalus before and after a v-p shunt. lcgu was decreased throughout the brain in hydrocephalus. the most severely affected regions were found in the cortex, with which a marked degree of subcortical cerebrospinal fluid (csf) edema was associated; regions in the brain-stem structures were less affected. these metabolic disturbances were improved in many regions aft ...	1988	3185424
[hyperuricemia in the joint syndrome in children].		2011	3186400
[pediculosis of the hairy skin].		2011	3187261
[persistent pruritus ani].		2011	3187273
infectious mononucleosis with pleural effusion.	we have described a 10-year-old child in whom a pleural effusion complicated an otherwise typical case of im. although rare, pleural effusions are a possible complication of infectious mononucleosis, and im should be considered in the differential diagnosis of pleural effusions in children.	2011	3187635
thoracic cord compression in scheuermann's disease.	a 29-year-old man with spastic paraparesis of insidious onset was discovered to have thoracic cord compression by a combination of kyphosis and thoracic disc herniation. radiologic evaluation showed evidence of scheuermann's disease, of which thoracic kyphosis is one manifestation. neurologic signs are uncommon in scheuermann's disease and few cases have been successfully managed with resolution of neurologic deficit. this patient made a virtually complete recovery after thoracic cord decompress ...	1988	3187711
sinus node suppression in acute strokes--case reports.	the authors report on 5 patients, 4 of them observed over a period of only two months in one community hospital, who developed profound sinus node suppression in the early phase following acute strokes. this complication resulted in the death of 2; in the remaining 3, it was controlled by electrical cardiac pacing or intravenous atropine. in 3 patients, the strokes were due to subarachnoid hemorrhage, and in 2, they were secondary to vascular occlusion. in at least 4 patients, the prognosis seem ...	2011	3189950
progressive ankylosis in mice. an animal model of spondylarthropathy. i. clinical and radiographic findings.	to determine its similarity to human spondylarthropathies, we studied murine progressive ankylosis, a spontaneously occurring disorder of joints in mice. clinically, peripheral joints were inflamed initially, then became ankylosed in a predictable sequence from distal to proximal. forefeet were involved before hindfeet. axial joint involvement produced severe spinal ankylosis. extraarticular manifestations included balanitis and crusting skin lesions. radiographically, bony erosions and calcific ...	1988	3190783
characterization of two deletions that remove the entire human zeta-alpha globin gene complex (- -thai and - -fil).	we have fully characterized two alpha thalassaemia mutants that occur in southeast asia, - -thai and - -fil. each mutant is due to a deletion that removes the entire zeta-alpha-globin gene complex. localization of the 5' breakpoints described here, allows the identification of unique fragments that are specific for each of the two mutations. this information can be used to assess the frequency of these mutants in southeast asia and will be of value in prenatal testing for alpha thalassaemia in t ...	1988	3191033
[effect of the induction of liver cytochrome p-450 by a chemically inert fluorocarbon on the reactions of immediate and delayed hypersensitivity].	the effect of chemically inert perfluorodecalin (pfd) on the development of hypersensitive reactions of immediate and delayed types in guinea pigs and mice was studied. it was found that administration of pfd to animals both before sensitization (mice) and during the development of sensitization (guinea pigs) reduced the degree of the both types of hypersensitivity.	1988	3191983
mobile sequences in the pyruvate dehydrogenase complex, the e2 component, the catalytic domain and the 2-oxoglutarate dehydrogenase complex of azotobacter vinelandii, as detected by 600 mhz 1h-nmr spectroscopy.	600 mhz 1h-nmr spectroscopy demonstrates that the pyruvate dehydrogenase complex of azotobacter vinelandii contains regions of the polypeptide chain with intramolecular mobility. this mobility is located in the e2 component and can probably be ascribed to alanine-proline-rich regions that link the lipoyl subdomains to each other as well as to the e1 and e3 binding domain. in the catalytic domain of e2, which is thought to form a compact, rigid core, also conformational flexibility is observed. i ...	1988	3191993
remarks by governor michael n. castle. professional conference on aids.		2009	3192022
a survey of family planning in the philippines.	a multicenter survey of 400 married filipino women 15-40 years of age conducted in 1986 by family health international and the international health foundation provided valuable information on contraceptive use in the philippines, as well as factors influencing such practices. the respondents, who were drawn from 10 urban communities in metro manila and 10 rural communities in nueva ecija province, averaged 31.5 years of age and had a mean number of 2.9 children. 32% of respondents indicated they ...	2011	3192555
negative life events, coping responses, and combat-related psychopathology: a prospective study.		2011	3192822
new initiatives in the investigation of rape.		2011	3193914
hla and hydatidiform mole. i. hla and abo antigen frequencies in couples with androgenetic and diandric conceptuses.	hla and abo antigen frequencies and mating rates were studied in couples with hydatidiform mole with known genomic origin. hla-a,b antigen frequencies among 60 patients and 59 spouses were not different from those found in the background population, neither in the subgroups regarded alone nor in the entire series. although not significant, an excess of hla-drw6 found in patients with androgenetic conceptions may be related to the anucleate ovi observed with androgenesis. the distribution of abo ...	2011	3194901
sample size: when is enough enough?		2011	3195627
the disposition of [2,3-14c]-methyl and [2,3-14c]-2-ethylhexyl acrylate in male wistar albino rats.	the disposition of methyl [2,3-14c]-acrylate (ma) and 2-ethylhexyl [2,3-14c]-acrylate (eha) following intraperitoneal and oral administration to rats has been studied. the 14c found in the tissues was mainly associated with liver, kidneys and lungs. loss of 14c from these tissues occurred fairly rapidly, excluding the rats given eha intraperitoneally. most of the administered acrylates underwent rapid metabolism and excretion with expired air (more than 50% of the dose and urine (10-50% of the d ...	1988	3196152
dog owners and their use of veterinary services.		1988	3198454
phaeohyphomycosis caused by alternaria alternata in a cat.	phaeohyphomycosis caused by alternaria alternata was diagnosed in a 6-year-old cat. a lesion in the nose resulted in enlargement of the dorsum of the nose. similar appearing lesions had been removed from the dorsum of the nose 1 and 4 years earlier. the lesion recurred 3 months after surgical excision and irregular administration of ketoconazole. a second cytoreductive operation followed by 5 months' treatment with ketoconazole resolved the infection. nasal trauma occurring at 8 months and at 5 ...	1988	3198465
microscopic effects of predator digestion on the surfaces of bones and teeth.	concentrations of small fossil mammals are frequently encountered in cenozoic deposits, but the causes for such accumulations have seldom been determined. in many cases the tooth, jaw, and limb fragments appear to be well-preserved under light microscopy, and it is difficult to differentiate damage due to predator digestion from breakage and abrasion due to physical agents. in order to find more specific evidence of predator digestion, we used a scanning electron microscope (sem) to examine the ...	2011	3201198
how important are randomized clinical trials for clinical practice?		2011	3202012
[scleroderma and circulating anticoagulant of the antiprothrombinase type].		2011	3202529
delta-aminolaevulinate synthase: mechanism of its response to malathion.		2011	3202912
a novel 190 kda calmodulin-binding protein associated with brain actomyosin.	we present evidence for a novel calmodulin-binding protein associated with ca2+-sensitive, non-muscle actomyosin from rabbit brain. gel filtration chromatography of brain actomyosin and sds-page analysis of resulting fractions revealed the presence of a stable complex of a 190 kda polypeptide and calmodulin. furthermore, brain actomyosin was retained on a column of conjugated calmodulin-sepharose 4b and eluted by 6 m urea in the presence of ca2+. further elution with 6m urea plus egta released t ...	1988	3203157
ana president urges empowerment of staff nurses.		2011	3205705
[selective biopsy of plaque material for cell cultivation].		2011	3206337
[ontogenetic characteristics of ascorbic acid binding by nerve tissue proteins].	the highest ascorbic acid content has been found in a low-molecular fraction (m. w. less than 6000) of water-soluble proteins from brain tissue homogenates of rats, the lowest one--in a high-molecular fraction (m. w. about 65,000). the content of protein-bound ascorbic acid decreases during postnatal life. this process is accompanied by changes in the ratio of the reduced and oxidated forms of the ascorbic acid in favour of the latter.	1988	3206951
significance and use of threshold limit values with reference to "corporate influence on threshold limit values" by castleman and ziem.		2011	3207108
osmotic fragility model for red cell populations.	a model that predicts the osmotic fragility curve of a red cell population is developed by relating the critical osmotic pressure to the size distribution of the cells, determined by resistive pulse spectroscopy. two of the parameters involved, namely the normalized osmotic volume correction, b, and the swelling index, k, are previously determined from the experimental average properties of the population. from these values the critical volume of the cell is obtained, and is shown to be 6-12% la ...	2011	3207827
connective tissue remodelling in the ovine cervix during pregnancy and at term.	cervical ripening and dilation in the ewe has been quantitated in terms of the connective tissue content of the tissue and the biosynthesis of the macromolecular components which make up the extracellular matrix of this tissue. during pregnancy there is a marked increase in the total tissue mass of the cervix along with the total mass of hydroxyproline (collagen) and hexuronate (proteoglycans and hyaluronate). the concentration of hydroxyproline of the cervix based on wet weight of the tissue de ...	1988	3208512
connective tissue remodelling in the ovine cervix during pregnancy and at term.	cervical ripening and dilation in the ewe has been quantitated in terms of the connective tissue content of the tissue and the biosynthesis of the macromolecular components which make up the extracellular matrix of this tissue. during pregnancy there is a marked increase in the total tissue mass of the cervix along with the total mass of hydroxyproline (collagen) and hexuronate (proteoglycans and hyaluronate). the concentration of hydroxyproline of the cervix based on wet weight of the tissue de ...	1988	3208512
conflict and the friendship relations of young children.	the purpose of this investigation was to compare conflicts occurring between young children and their friends to those occurring between nonfriends. 53 children with a median age of 4 years, 3 months were observed and interviewed to determine who were mutual friends, unilateral associates, or neutral associates. 146 conflicts were also observed. conflicts between mutual friends, as compared to those occurring between neutral associates: (a) did not occur less frequently, differ in length, or dif ...	2011	3208570
dissociation of the lateral and medial cerebellum in movement timing and movement execution.	in a previous study (ivry and keele, in press), cerebellar patients were found to be impaired on both a motor and a perceptual task which required accurate timing. this report presents case study analyses of seven patients with focal lesions in the cerebellum. the lesions were predominantly in the lateral, hemispheric regions for four of the patients. for the remaining three patients, the lesions were centered near the medial zone of the cerebellum. the clinical evaluation of the patients also w ...	2011	3208855
paracrine control of immature sertoli cells by adult germ cells, in the rat (an in vitro study). cell-cell interactions within the testis.	enriched populations of germ cells prepared from adult rats were found to influence 20-day-old rat sertoli cell secretory activity by stimulating androgen-binding protein (abp) and inhibiting oestradiol-17 beta production in the presence of follicle-stimulating hormone (fsh) as well as of dibutyryl cyclic amp (dbcamp). among the different populations tested in coculture, pachytene spermatocytes were the most effective at stimulating abp and inhibiting oestradiol production, whereas early spermat ...	1988	3208988
functional and biochemical features of alcohol dehydrogenase in four species of the obscura group of drosophila.	the biochemical features of adh of four drosophila species of the obscura group have been studied. the relationship between ethanol tolerance and adh activity has been investigated. propan-2-ol and acetone concentrations have been determined in propan-2-ol treated flies and adh activity has been followed during 96 h of propan-2-ol treatment. data on the adh system confirm constructed phylogenies based on electrophoretic variation and chromosome homologies.	2011	3209073
changes in lysosomal enzyme activities recognized in granulocytes from patients with carcinomas of the gastrointestinal tract.		2011	3209925
[a combination of an accessory large intestine and teratoid cysts of the intrapelvic tissue].		2011	3210612
cough threshold to citric acid in diabetic patients with and without autonomic neuropathy.	the cough reflex has been investigated in insulin dependent diabetic patients with and without autonomic neuropathy. the cough response to inhaled citric acid was determined in eight patients with diabetes who had severe autonomic neuropathy and compared with that in 10 who had no evidence of neuropathy. the patients with autonomic neuropathy had a higher median threshold for the cough response to citric acid (median 50%, range 20- greater than 100%) than non-neuropathic control patients (median ...	2007	3212754
cough threshold to citric acid in diabetic patients with and without autonomic neuropathy.	the cough reflex has been investigated in insulin dependent diabetic patients with and without autonomic neuropathy. the cough response to inhaled citric acid was determined in eight patients with diabetes who had severe autonomic neuropathy and compared with that in 10 who had no evidence of neuropathy. the patients with autonomic neuropathy had a higher median threshold for the cough response to citric acid (median 50%, range 20- greater than 100%) than non-neuropathic control patients (median ...	2007	3212754
gut-associated lymphoid tissue in the large intestine of calves. ii. electron microscopy.	scanning electron microscopy of lymphoid tissue in the large intestine of three germfree calves (age 3, 6, and 7 days) revealed two different units: propria nodules and lymphoglandular complexes (lgc). propria nodules had lymphoid tissue predominantly in lamina propria and were covered by distinct follicle-associated epithelium which lacked goblet cells; nodules were surrounded by wide crypts, which were also lined by follicle-associated epithelium towards the luminal side. lymphoglandular compl ...	1988	3212895
[fibrinogen glue in ophthalmology. its use in corneal ulcers].		2011	3214902
how patients know that nurses care about them.		2011	3216234
[blood levels of ca-50, ca-19.9, ca-125, enolase, ca-15.3 and carcinoembryonic antigen in non-cancerous bronchopulmonary pathology].	at present we do not possess a specific marker of broncho-pulmonary cancers. we propose to test the specificity of six serum markers labelled by radio-immunological methods (ca-50, ca-19.9, ca-125, ca-15.3, enolase, ace) in 60 patients suffering from non-tumoural broncho-pulmonary disorders: chronic airflow obstruction = 28, acute infective bronchopulmonary disorders = 23, allergy = 9. we have not found any correlation between the percentage of false positives and sex, age or smoking. on the oth ...	2011	3217589
[measurement of arterial pressure].		2011	3217679
[facilitatory effect of trifluoperazine on adrenergic transmitter release from rat portal vein].		1988	3218532
arautp-affi-gel 10: a novel affinity absorbent for the specific purification of dna polymerase alpha-primase.	for the specific purification of eukaryotic dna-dependent dna polymerase alpha, we prepared two novel affinity resins bearing 5-(e)-(4-aminostyryl) arautp as a ligand. one of them was arautp-sepharose 4b which was coupled directly with the ligand and the other was arautp-affi-gel 10 which was coupled with the ligand through a spacer. no dna polymerase alpha-primase activity from cherry salmon (oncorhynchus masou) testes was bound on the arautp-sepharose 4b in all cases examined. on the other han ...	1988	3218743
[surgery of cholesteatoma ears with good hearing].		2011	3219644
comparison of in vitro dissolution of proprietary methyl dopa preparations.		2011	3219716
economic implications of oral treatment replacing parenteral therapy in antimicrobial chemotherapy.	the cost of antimicrobial chemotherapy is a major part of the total hospital pharmacy cost. parenteral administration is considerably more expensive than oral and until recently was the only available therapy for nosocomial and resistant bacterial infections. apart from the cost of the antimicrobial agent itself, many other factors such as the infusion sets, catheters and cannulae, monitoring of blood to avoid toxicity and other laboratory investigations will influence the costs. the introductio ...	2010	3219753
affinity of microorganisms of the genus ureaplasma to the reproductive organs of cattle.	the purpose of this work was to define more precisely the role of ureaplasma organisms in the aetiology of granular vulvovaginitis and balanoposthitis (gvvbp) of cattle. to contribute to this question the frequency and degree of infection with ureaplasmas in two main groups of cattle was taken into account: (a) in cattle with symptoms of the mentioned disease, (b) in cattle without clinical symptoms. the samples of semen from 301 sires with symptoms of gvvbp and from 43 healthy sires as also vag ...	1988	3219829
[clinical and hemodynamic effects of lipo pge1 in cerebral infarction].	prostaglandin (pg) e1 is a potent vasodilator on the peripheral vessels and also has an inhibitory action of platelet aggregation. lipo pge1, the lipid emulsified pge1 has much longer half life time in the circulation than pge1 which is rapidly inactivated in the lung. the purpose of this investigation was to study the clinical and hemodynamic effect of lipo pge1 on the 15 patients with acute or subacute focal cerebral ischemia. of these patients, five had evidence of internal carotid artery occ ...	2010	3221965