Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| immunogenicity and safety of hepatitis b vaccination in patients with type 2 diabetes in china: an open-label randomized controlled trial. | hepatitis b virus (hbv) infection remains a global public health challenge. patients with diabetes are at greater risk of hbv infection than healthy people. the immunogenicity and safety of two major hepatitis b vaccines were evaluated in chinese patients with diabetes. | 2021 | 33992438 |
| identification of potent epitopes on hexon capsid protein and their evaluation as vaccine candidates against infections caused by members of adenoviridae family. | adenoviruses cause economically important diseases in vertebrates. effective vaccines against adenoviral diseases are currently lacking. here, we report a highly conserved epitopic region on hexon proteins of adenoviruses that generate a strong immune response when used as a virus-like-particle (vlp) vaccine, produced by inserting the epitopic region into the core protein of hepatitis b virus. for evaluation of its protective efficacy, the epitopic region from a representative adenovirus, fowl a ... | 2021 | 34030897 |
| direct antiviral agents in hepatitis c virus related liver disease: don't count the chickens before they're hatched. | since molecules with direct-acting antiviral (daa) became available, the landscape of the treatment of hepatitis c virus (hcv) infection has completely changed. the new drugs are extremely effective in eradicating infection, and treatment is very well tolerated with a duration of 8-12 wk. this review aims to report the outstanding clinical benefits of daa and to highlight their critical disadvantages, identifying some clinically relevant hot topics. first, do the rates of virological response re ... | 2021 | 34135553 |
| application of the woodchuck animal model for the treatment of hepatitis b virus-induced liver cancer. | this review describes woodchucks chronically infected with the woodchuck hepatitis virus (whv) as an animal model for hepatocarcinogenesis and treatment of primary liver cancer or hepatocellular carcinoma (hcc) induced by the hepatitis b virus (hbv). since laboratory animal models susceptible to hbv infection are limited, woodchucks experimentally infected with whv, a hepatitis virus closely related to hbv, are increasingly used to enhance our understanding of virus-host interactions, immune res ... | 2021 | 34163570 |
| glucose homeostasis is dysregulated in ducks infected with duck hepatitis b virus. | the association between hepatitis b virus (hbv) infection and the development of diabetes remains controversial. this study examined the effect of hbv infection on glucose homeostasis using a duck hbv (dhbv) model. | 2021 | 34167117 |
| analysis of codon usage of horseshoe bat hepatitis b virus and its host. | in the present analysis, codon usage strategies and base distribution of horseshoe bat hepatitis b virus (hbhbv) were analyzed and compared with its host rhinolophus sinicus, as no work was yet reported. the magnitude of synonymous codon usage bias (cub) in the virus and its host was low with higher proportion of the base c. notably, 21 more frequently used codons, 19 less frequently used codons and 3 underrepresented codons (tcg, acg and gcg) were found to be similar in both virus and its host ... | 2021 | 34171764 |
| involvement of innate immune receptors in the resolution of acute hepatitis b in woodchucks. | the antiviral property of small agonist compounds activating pattern recognition receptors (prrs), including toll-like and rig-i receptors, have been preclinically evaluated and are currently tested in clinical trials against chronic hepatitis b (chb). the involvement of other prrs in modulating hepatitis b virus infection is less known. thus, woodchucks with resolving acute hepatitis b (ahb) after infection with woodchuck hepatitis virus (whv) were characterized as animals with normal or delaye ... | 2021 | 34367179 |