Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria. | current antimicrobial susceptibility testing has limited screening capability for identifying empirical antibiotic combinations to treat severe bacterial infections with multidrug-resistant (mdr) organisms. we developed a new antimicrobial susceptibility assay using automated ultra-high-throughput screen technology in combination with a simple bacterial growth assay. a rapid screening of 5170 approved drugs and other compounds identified 25 compounds with activities against mdr klebsiella pneumo ... | 2016 | 27826141 |
| dcia is an ancestral replicative helicase operator essential for bacterial replication initiation. | delivery of the replicative helicase onto dna is an essential step in the initiation of replication. in bacteria, dnac (in escherichia coli) and dnai (in bacillus subtilis) are representative of the two known mechanisms that assist the replicative helicase at this stage. here, we establish that these two strategies cannot be regarded as prototypical of the bacterial domain since dnac and dnai (dna[ci]) are present in only a few bacterial phyla. we show that dna[ci] was domesticated at least seve ... | 2016 | 27830752 |
| a structural, epidemiological & genetic overview of klebsiella pneumoniae carbapenemases (kpcs). | klebsiella pneumoniae carbapenemases (kpcs) are plasmid encoded carbapenem hydrolyzing enzymes which have the potential to spread widely through gene transfer. the instability of upstream region of blakpc accelerates emergence of different isoforms. routine antibiotic susceptibility testing failed to detect kpc producers and some commercial kits have been launched for early identification of kpc producers. notable among the drugs under development against kpc are mostly derivatives of polymixin; ... | 2016 | 27834322 |
| risk of infection in primary, elective total hip arthroplasty with direct anterior approach or lateral transgluteal approach: a prospective cohort study of 1104 hips. | the direct anterior approach (daa) is increasingly popular for hip replacement. however, the small incision and the location near to the groin might increase the risk of periprosthetic joint infection (pji). we asked the questions (i) whether there is an increased risk of infection for this approach, and (ii) whether the spectrum of microorganisms differs between patients with daa and those with lateral transgluteal approach (lat). | 2016 | 27842584 |
| effect of bio-engineering on size, shape, composition and rigidity of bacterial microcompartments. | bacterial microcompartments (bmcs) are proteinaceous organelles that are found in a broad range of bacteria and are composed of an outer shell that encases an enzyme cargo representing a specific metabolic process. the outer shell is made from a number of different proteins that form hexameric and pentameric tiles, which interact to allow the formation of a polyhedral edifice. we have previously shown that the citrobacter freundii bmc associated with 1,2-propanediol utilization can be transferre ... | 2016 | 27845382 |
| microbiome analysis reveals the abundance of bacterial pathogens in rousettus leschenaultii guano. | bats are crucial for proper functioning of an ecosystem. they provide various important services to ecosystem and environment. while, bats are well-known carrier of pathogenic viruses, their possible role as a potential carrier of pathogenic bacteria is under-explored. here, using culture-based approach, employing multiple bacteriological media, over thousand bacteria were cultivated and identified from rousettus leschenaultii (a frugivorous bat species), the majority of which were from the fami ... | 2016 | 27845426 |
| bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides. | constituents from polyalthia cerasoides, stem bark methanol extract, were previously documented. this study reports the first isolation of bioactive n-(4-hydroxy-β-phenethyl)-4-hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. trace essential elements were found in the hexane extract in ppm level. the plant extracts were evaluated for their antimicrobial and antioxidative activities. ... | 2011 | 27857661 |
| in vivo horizontal dissemination of the blakpc-2 gene carried on diverse genetic platforms among clinical isolates of enterobacteriaceae. | this study investigated the molecular characteristics of six blakpc-positive enterobacteriaceae recovered from three patients in argentina. antimicrobial susceptibility testing was performed following clinical and laboratory standards institute (clsi) 2014 recommendations. molecular characterisation of the isolates was performed by biparental conjugation, pcr, sequencing, s1 nuclease restriction, and southern blot hybridisation with a blakpc probe using standard protocols and conditions. the iso ... | 2015 | 27873711 |
| study of the antibacterial and antifungal activities of synthetic benzyl bromides, ketones, and corresponding chalcone derivatives. | several applications of chalcones and their derivatives encouraged researchers to increase their synthesis as an alternative for the treatment of pathogenic bacterial and fungal infections. in the present study, chalcone derivatives were synthesized through cross aldol condensation reaction between 4-(n,n-dimethylamino)benzaldehyde and multiarm aromatic ketones. the multiarm aromatic ketones were synthesized through nucleophilic substitution reaction between 4-hydroxy acetophenone and benzyl bro ... | 2016 | 27877017 |
| non-o157:h7 shiga toxin producing diarrhoeagenic escherichia coli (stec) in southern india: a tinderbox for starting epidemic. | outbreaks due to non-o157:h7 shiga toxin producing escherichia coli (stec) resulting in haemolytic uraemic syndrome (hus) have garnered much attention because of associated mortality transcending across continents and also because diarrhoea due to e.coli itself is rare in developed countries. the actual incidence of non-o157:h7 stec in sporadic acute diarrhoea is not fully elucidated, both in developing as well as in developed countries. due to larger extent of faecal-oral transmission in develo ... | 2016 | 27891338 |
| diversity and evolutionary analysis of iron-containing (type-iii) alcohol dehydrogenases in eukaryotes. | alcohol dehydrogenase (adh) activity is widely distributed in the three domains of life. currently, there are three non-homologous nad(p)+-dependent adh families reported: type i adh comprises zn-dependent adhs; type ii adh comprises short-chain adhs described first in drosophila; and, type iii adh comprises iron-containing adhs (feadhs). these three families arose independently throughout evolution and possess different structures and mechanisms of reaction. while types i and ii adhs have been ... | 2016 | 27893862 |
| identification of escherichia coli and trueperella pyogenes isolated from the uterus of dairy cows using routine bacteriological testing and fourier transform infrared spectroscopy. | uterine disorders are common postpartum diseases in dairy cows. in practice, uterine treatment is often based on systemic or locally applied antimicrobials with no previous identification of pathogens. accurate on-farm diagnostics are not available, and routine testing is time-consuming and cost intensive. an accurate method that could simplify the identification of uterine pathogenic bacteria and improve pathogen-specific treatments could be an important advance to practitioners. the objective ... | 2016 | 27894322 |
| distribution and classification of serine β-lactamases in brazilian hospital sewage and other environmental metagenomes deposited in public databases. | β-lactam is the most used antibiotic class in the clinical area and it acts on blocking the bacteria cell wall synthesis, causing cell death. however, some bacteria have evolved resistance to these antibiotics mainly due the production of enzymes known as β-lactamases. hospital sewage is an important source of dispersion of multidrug-resistant bacteria in rivers and oceans. in this work, we used next-generation dna sequencing to explore the diversity and dissemination of serine β-lactamases in t ... | 2016 | 27895627 |
| antioxidant and antibacterial activity of the beverage obtained by fermentation of sweetened lemon balm (melissa officinalis l.) tea with symbiotic consortium of bacteria and yeasts. | kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (camellia sinensis l.) with symbiotic consortium of bacteria and yeasts (scoby). in this study, lemon balm (melissa officinalis l.) was used as the only nitrogen source for kombucha fermentation. during the seven-day fermentation process, ph value, titratable acidity (ta), total phenolic content, phenolic compounds, and antioxidant activity against hydroxyl (˙oh) and 1,1-diphenyl-2-pic ... | 2014 | 27904315 |
| prevalence of escherichia coli o157:h7 and enterobacteriaceae on hands of workers in halal cattle abattoirs in peninsular malaysia. | several occupational diseases of multiple origins are encountered among abattoir workers. presence of indicator microorganisms (coliforms) on hands of workers can be used a gauge for hygienic practices. | 2016 | 27904427 |
| methylome analysis of two xanthomonas spp. using single-molecule real-time sequencing. | single-molecule real-time (smrt) sequencing allows identification of methylated dna bases and methylation patterns/motifs at the genome level. using smrt sequencing, diverse bacterial methylomes including those of helicobacter pylori, lactobacillus spp., and escherichia coli have been determined, and previously unreported dna methylation motifs have been identified. however, the methylomes of xanthomonas species, which belong to the most important plant pathogenic bacterial genus, have not been ... | 2016 | 27904456 |
| clinical experience of patients receiving doripenem-containing regimens for the treatment of healthcare-associated infections. | in this study, we retrospectively reviewed the clinical experience of patients receiving doripenem-containing regimens for the treatment of healthcare-associated infections (hcais) in a tertiary care center and assessed the clinical usefulness of doripenem therapy in this clinical setting. in this retrospective study, the medical records of all adult patients who had ever received doripenem-containing therapy for the treatment of hcais were reviewed between september 1, 2012 and august 31, 2014, ... | 2016 | 27907197 |
| genetically unrelated multidrug- and carbapenem-resistant citrobacter freundii detected in outpatients admitted to a portuguese hospital. | non-clonal, carbapenem- and multidrug-resistant citrobacter freundii isolates were collected from unrelated outpatients admitted to a portuguese hospital emergency department. one patient lived in a nursing home and was never hospitalised, whereas the other patient was repeatedly hospitalised in this hospital. the aim of this study was to unveil the molecular mechanisms associated with the carbapenem resistance of these isolates and to assess its potential dissemination. | 2017 | 27915087 |
| isolation of a facultative anaerobic exoelectrogenic strain lz-1 and probing electron transfer mechanism in situ by linking uv/vis spectroscopy and electrochemistry. | a new facultative anaerobic exoelectrogenic strain lz-1, belonging to citrobacter freundii, has been isolated. this strain can produce current densities of 843.9 and 865.6μacm(-2) using citrate or acetate as carbon source in a three-electrode configuration. the electricity generation performance was also analyzed in a dual-chamber mfc system, reaching a maximum power density of 1233mwm(-2). in addition to acetate and citrate, other carbon sources such as pyruvate, formate, acetate, citrate and f ... | 2017 | 27918963 |
| clinical implications of paracoccus yeeii bacteremia in a patient with decompensated cirrhosis. | infections in patients with cirrhosis are common among those who develop variceal hemorrhage. prophylactic antimicrobial treatment with third generation cephalosporins is recommended in patients with advanced cirrhosis and gastrointestinal hemorrhage. however no infectious source is identified in up to 50% of patients with cirrhosis and clinical sepsis. we report the first case of paracoccus yeeii bacteremia in a patient with decompensated cirrhosis who presented with variceal hemorrhage. this r ... | 2016 | 27920982 |
| clinical implications of paracoccus yeeii bacteremia in a patient with decompensated cirrhosis. | infections in patients with cirrhosis are common among those who develop variceal hemorrhage. prophylactic antimicrobial treatment with third generation cephalosporins is recommended in patients with advanced cirrhosis and gastrointestinal hemorrhage. however no infectious source is identified in up to 50% of patients with cirrhosis and clinical sepsis. we report the first case of paracoccus yeeii bacteremia in a patient with decompensated cirrhosis who presented with variceal hemorrhage. this r ... | 2016 | 27920982 |
| comparison of gram-negative and gram-positive hematogenous pyogenic spondylodiscitis: clinical characteristics and outcomes of treatment. | to the best of our knowledge, no study has compared gram-negative bacillary hematogenous pyogenic spondylodiscitis (gnb-hps) with gram-positive coccal hematogenous pyogenic spondylodiscitis (gpc-hps) regarding their clinical characteristics and outcomes. | 2016 | 27923346 |
| outbreak of klebsiella pneumoniae carbapenemase-producing citrobacter freundii at a tertiary acute care facility in miami, florida. | objective to describe the investigation and control of a rare cluster of klebsiella pneumoniae carbapenemase-producing citrobacter freundii in a hospital in southern florida. methods an epidemiologic investigation, review of infection prevention procedures, and molecular studies including whole genome sequencing were conducted. results an outbreak of k. pneumoniae carbapenemase-3-producing c. freundii was identified at a tertiary hospital in florida in 2014. of the 6 cases identified, 3 occurred ... | 2017 | 27923418 |
| the clonal relationship among the citrobacter freundii isolated from the main hospital in kermanshah, west of iran. | citrobacter freundii is an opportunistic pathogen causing nosocomial infections and resistant to various antibiotics. we aimed to determine the clonal relationship of c. freundii isolates using pulsed-field gel electrophoresis (pfge). | 2016 | 27928484 |
| a retrospective study of pyogenic liver abscess focusing on klebsiella pneumoniae as a primary pathogen in china from 1994 to 2015. | pyogenic liver abscess (pla) is a common intra-abdominal infection in adults. in this study, we aim to explore demographic and clinical characteristics of pla focusing on klebsiella pneumoniae (k. pneumoniae) induced pla (kp-pla) in mainland china. a retrospective review of medical records from all patients with kp-pla admitted to a tertiary teaching hospital over a 21-year period (1994-2015) was performed. among 296 pla cases with confirmed culture-positive data, k. pneumoniae was revealed as t ... | 2016 | 27929082 |
| cooperative evolutionary strategy between the bacteriome and mycobiome. | nonhealing chronic wounds are all unique in origin and circumstance, and attempting to isolate a single etiology for the failure of a wound to heal is daunting. wounds represent complex systems of multispecies fungal and bacterial biofilms. the survival strategies of interactive microbial communities have led to cooperative evolutionary strategies that culminate in biofilm formation. in microbial dysbiosis, biofilms are beneficial to both bacterial and fungal communities but detrimental to the h ... | 2016 | 27935844 |
| isolation, antimicrobial susceptibility profile and detection of sul1, blatem, and blashv in amoxicillin-clavulanate-resistant bacteria isolated from retail sausages in kampar, malaysia. | due to the overuse of antibiotics in livestock as a growth-promoting agent, the emergence of multi-antibiotic resistant bacteria is becoming a concern. | 2016 | 27942365 |
| enterohemorrhagic escherichia coli o157 in milk and dairy products from libya: isolation and molecular identification by partial sequencing of 16s rdna. | the aim of this work was to isolate and molecularly identify enterohemorrhagic escherichia coli (ehec) o157 in milk and dairy products in libya, in addition; to clear the accuracy of cultural and biochemical identification as compared with molecular identification by partial sequencing of 16s rdna for the existing isolates. | 2016 | 27956766 |
| risk factors for bacteremia in patients with urinary catheter-associated bacteriuria. | catheter-associated bacteriuria is complicated by secondary bacteremia in 0.4% to 4.0% of cases. the directly attributable mortality rate is 12.7%. | 2016 | 27965229 |
| comprehensive genome analysis of carbapenemase-producing enterobacter spp.: new insights into phylogeny, population structure, and resistance mechanisms. | knowledge regarding the genomic structure of enterobacter spp., the second most prevalent carbapenemase-producing enterobacteriaceae, remains limited. here we sequenced 97 clinical enterobacter species isolates that were both carbapenem susceptible and resistant from various geographic regions to decipher the molecular origins of carbapenem resistance and to understand the changing phylogeny of these emerging and drug-resistant pathogens. of the carbapenem-resistant isolates, 30 possessed blakpc ... | 2016 | 27965456 |
| microbiological quality of fresh nopal juice. | the consumption of fresh nopal cactus juice is widely popular among health-conscious consumers in mexico. the juice is prepared from fresh cladodes that have only been rinsed with tap water and are not subjected to a pasteurization or terminal bacterial reduction process. the aim of this study was to evaluate the microbial quality of commercially available fresh juices (n = 162) made with nopal in texcoco, state of mexico, during the summer and spring season. standard microbiological methods, th ... | 2016 | 27973398 |
| identification of five novel salmonella typhi-specific genes as markers for diagnosis of typhoid fever using single-gene target pcr assays. | salmonella typhi (s. typhi) causes typhoid fever which is a disease characterised by high mortality and morbidity worldwide. in order to curtail the transmission of this highly infectious disease, identification of new markers that can detect the pathogen is needed for development of sensitive and specific diagnostic tests. in this study, genomic comparison of s. typhi with other enteric pathogens was performed, and 6 s. typhi genes, that is, sty0201, sty0307, sty0322, sty0326, sty2020, and sty2 ... | 2016 | 27975062 |
| predominance of ctx-m-15 among esbl producers from environment and fish gut from the shores of lake victoria in mwanza, tanzania. | extended-spectrum beta-lactamase (esbl)-producing bacteria are a common cause of healthcare and community-associated infections worldwide. the distribution of such isolates in the environment and their presence in fish as a result of sewage contamination is not well-studied. here we examined fish and environmental samples from mwanza city for the presence of esbl-producing bacteria. from 196 fish sampled from local markets, 26 (13.3%) contained lactose-fermenting esbl-producing bacteria, while 3 ... | 2016 | 27990135 |
| evaluation of the xpert carba-r (cepheid) assay using contrived bronchial specimens from patients with suspicion of ventilator-associated pneumonia for the detection of prevalent carbapenemases. | there is a critical need for rapid diagnostic methods for multidrug-resistant (mdr) pathogens in patients with a suspicion of ventilator-associated pneumonia (vap). the xpert carba-r detects 5 targets for carbapenemase-producing organisms (blakpc, blandm, blavim, blaoxa-48, and blaimp-1). our objective was to evaluate the performance of this assay directly on bronchial aspirates and to correlate the cycle number for a positive result (ct) with the bacterial count. bronchial aspirates from patien ... | 2016 | 27992521 |
| the most common detected bacteria in sputum of patients with community acquired pneumonia (cap) treated in hospital. | community acquired pneumonia (cap) is the most common infective pulmonary disease. | 2016 | 27994296 |
| comparative metabolic state of microflora on the surface of the anode electrode in a microbial fuel cell operated at different ph conditions. | the metabolic state of microflora (mixed microbial cultures) in microbial fuel cells (mfcs) is currently unclear. metabolomic analyses were conducted of microflora growing on the anodic electrodes of mfcs operated at ph 7.0, 5.5, or 4.0 and utilizing starch as the major carbon substrate. a much higher current was produced at ph 7.0 than at ph 5.5 and 4.0, correlating with an increased population ratio of geobacter species to the total bacteria growing on the electrode. most intracellular metabol ... | 2016 | 28000139 |
| aerobic and anaerobic biosynthesis of nano-selenium for remediation of mercury contaminated soil. | selenium (se) nanoparticles are often synthesized by anaerobes. however, anaerobic bacteria cannot be directly applied for bioremediation of contaminated top soil which is generally aerobic. in this study, a selenite-reducing bacterium, citrobacter freundii y9, demonstrated high selenite reducing power and produced elemental nano-selenium nanoparticles (nano-se(0)) under both aerobic and anaerobic conditions. the biogenic nano-se(0) converted 45.8-57.1% and 39.1-48.6% of elemental mercury (hg(0) ... | 2017 | 28011305 |
| urinary tract infections in romanian patients with diabetes: prevalence, etiology, and risk factors. | patients with diabetes mellitus (dm) have an increased risk of infections, especially urinary tract infections (utis). the aim of this study was to assess the prevalence and etiology of utis and identify the risk factors for their development in patients with dm. | 2016 | 28031715 |
| urinary tract infections in romanian patients with diabetes: prevalence, etiology, and risk factors. | patients with diabetes mellitus (dm) have an increased risk of infections, especially urinary tract infections (utis). the aim of this study was to assess the prevalence and etiology of utis and identify the risk factors for their development in patients with dm. | 2016 | 28031715 |
| secondary metabolites from bacillus amyloliquefaciens isolated from soil can kill burkholderia pseudomallei. | bacillus species are gram-positive bacteria found in abundance in nature and their secondary metabolites were found to possess various potential activities, notably antimicrobial. in this study, bacillus amyloliquefaciens n2-4 and n3-8 were isolated from soil and their metabolites could kill burkholderia pseudomallei, a gram-negative pathogenic bacterium also found in soil in its endemic areas. moreover, the metabolites were able to kill drug resistant isolates of b. pseudomallei and also inhibi ... | 2017 | 28050857 |
| rapid molecular approach for simultaneous detection of salmonella spp., shigella spp., and vibrio cholera. | gastrointestinal tract infection is still one of the serious public health problems in many geographic areas and is endemic in most countries including iran. early detection of the gastrointestinal tract pathogens can be extremely important. the aim of the current study was to apply a shortened time-multiplex polymerase chain reaction (pcr) for rapid and simultaneous detection of salmonella spp., shigella spp., and vibrio cholera. | 2016 | 28053842 |
| microbial degradation of a recalcitrant pesticide: chlordecone. | chlordecone (kepone®) is a synthetic organochlorine insecticide (c10cl10o) used worldwide mostly during the 1970 and 1980s. its intensive application in the french west indies to control the banana black weevil cosmopolites sordidus led to a massive environmental pollution. persistence of chlordecone in soils and water for numerous decades even centuries causes global public health and socio-economic concerns. in order to investigate the biodegradability of chlordecone, microbial enrichment cult ... | 2016 | 28066351 |
| bacterial contamination of platelet products in the blood transfusion center of isfahan, iran. | aim: overall the risk of transfusion transmitted infections has decreased, especially viral infections like hiv and hepatitis b and c. bacterial contamination of blood and its cellular components, however, remains a common microbiological cause of transfusion associated morbidity and mortality. platelets pose a special risk given their preservation methods. the incidence of these episodes needs to be assessed and updated on regular basis to accurately manage the risk of transfusion transmitted b ... | 2016 | 28066700 |
| proceedings of réanimation 2017, the french intensive care society international congress. | 2017 | 28074415 | |
| the influence of antibiotic prophylaxis on bacterial resistance in urinary tract infections in children with spina bifida. | bacterial resistance to antibiotics is an increasingly threatening consequence of antimicrobial exposure for many decades now. in urinary tract infections (utis), antibiotic prophylaxis (ap) increases bacterial resistance. we studied the resistance patterns of positive urinary cultures in spina bifida children on clean intermittent catheterization, both continuing and stopping ap. | 2017 | 28081719 |
| detection of ampc β-lactamase producing bacteria isolated in neonatal sepsis. | the objective of this study was to determine the occurrence and antimicrobial profile of ampc β-lactamase producing bacteria. | 2016 | 28083055 |
| characterization of two polyvalent phages infecting enterobacteriaceae. | bacteriophages display remarkable genetic diversity and host specificity. in this study, we explore phages infecting bacterial strains of the enterobacteriaceae family because of their ability to infect related but distinct hosts. we isolated and characterized two novel virulent phages, sh6 and sh7, using a strain of shigella flexneri as host bacterium. morphological and genomic analyses revealed that phage sh6 belongs to the t1virus genus of the siphoviridae family. conversely, phage sh7 was cl ... | 2017 | 28091598 |
| development of an algorithm for phenotypic screening of carbapenemase-producing enterobacteriaceae in the routine laboratory. | carbapenemase-producing enterobacteriaceae (cpe) are difficult to identify among carbapenem non-susceptible enterobacteriaceae (nse). we designed phenotypic strategies giving priority to high sensitivity for screening putative cpe before further testing. | 2017 | 28095794 |
| implementation of short incubation maldi-tof ms identification from positive blood cultures in routine diagnostics and effects on empiric antimicrobial therapy. | results of blood culture (bc) diagnostics should be swiftly available to guide treatment of critically ill patients. conventional bc diagnostics usually performs species identification of microorganisms from mature solid medium colonies. species identification might be speed up by using matrix-assisted laser desorption ionization time-of-flight (maldi-tof) mass spectrometry (ms) of biomass from shortly incubated solid media. | 2017 | 28101334 |
| antimicrobial activity, ame resistance, and a-site binding studies of anthraquinone-neomycin conjugates. | the antibacterial effects of aminoglycosides are based on their association with the a-site of bacterial rrna and interference with the translational process in the bacterial cell, causing cell death. the clinical use of aminoglycosides is complicated by resistance and side effects, some of which arise from their interactions with the human mitochondrial 12s rrna and its deafness-associated mutations, c1494u and a1555g. we report a rapid assay that allows screening of aminoglycoside compounds to ... | 2017 | 28103015 |
| bacterial microcompartment-directed polyphosphate kinase promotes stable polyphosphate accumulation in e. coli. | processes for the biological removal of phosphate from wastewater rely on temporary manipulation of bacterial polyphosphate levels by phased environmental stimuli. in e. coli polyphosphate levels are controlled via the polyphosphate-synthesizing enzyme polyphosphate kinase (ppk1) and exopolyphosphatases (ppx and gppa), and are temporarily enhanced by ppk1 overexpression and reduced by ppx overexpression. we hypothesised that partitioning ppk1 from cytoplasmic exopolyphosphatases would increase a ... | 2017 | 28105684 |
| purification, characterization and functional analysis of the immune molecule lectin from the haemolymph of blue swimmer crab portunus pelagicus and their antibiofilm properties. | the present study reveals purification and characterization of immune molecule lectin from the haemolymph of blue swimmer crab portunus pelagicus (pp-lec). the pp-lec was purified by affinity chromatography with mannose coupled sepharose cl-4b column and it exhibits single band with a molecular weight of 155 kda in sds-page. the surface morphology of purified pp-lec displays the homogeneous nature of protein. a distinct peak with a retention time of 3.3 min was appeared in high performance liqui ... | 2017 | 28110033 |
| occurrence of extended-spectrum and ampc β-lactamases in multiple drug resistant salmonella isolates from clinical samples in lagos, nigeria. | salmonella spp. are important foodborne pathogens exhibiting increasing resistance to antimicrobial drugs. resistance to broad-spectrum β-lactams, mediated by extended-spectrum β-lactamase (esbl) and ampc β-lactamase enzymes is fast spreading and has had negative impacts on the clinical outcomes, particularly on third-generation cephalosporins. this study investigated the carriage of ampc gene among multidrug-resistant salmonella spp. from lagos, nigeria. | 2017 | 28144154 |
| osteopathic treatment in a patient with left-ventricular assist device with left brachialgia: a case report. | this study deals with an osteopathic approach used for a patient with left-ventricular assist device (l-vad) affected by left brachialgia. clinical examination revealed the presence of thoracic outlet syndrome and pectoralis minor syndrome, with compression of the left proximal ulnar nerve, related to the surgical sternotomy performed. the osteopathic techniques used can be classified as indirect and direct, addressed to the pectoralis minor and the first left rib, respectively. to our knowledge ... | 2017 | 28144166 |
| κ-carrageenan enhances lipopolysaccharide-induced interleukin-8 secretion by stimulating the bcl10-nf-κb pathway in ht-29 cells and aggravates c. freundii-induced inflammation in mice. | background. the dietary usage of carrageenan as common food additive has increased observably over the last 50 years. but there is substantial controversy about its safety. methods. we investigated whether the κ-carrageenan could enhance lipopolysaccharide-induced il-8 expression by studying its actions on the tlr4-nf-κb pathway. the aggravating effect of κ-carrageenan on citrobacter freundii dbs100-induced intestinal inflammation was also investigated in a mouse model. results. our data show th ... | 2017 | 28163398 |
| global molecular epidemiology of imp-producing enterobacteriaceae. | international data on the molecular epidemiology of enterobacteriaceae with imp carbapenemases are lacking. we performed short-read (illumina) whole-genome sequencing on a global collection of 38 imp-producing clinical enterobacteriaceae (2008 to 2014). imp-producing enterobacteriaceae (7 varieties within 11 class 1 integrons) were mainly present in the south pacific and asia. specific blaimp-containing integrons (in809 with blaimp-4, in722 with blaimp-6, and in687 with blaimp-14) were circulati ... | 2017 | 28167555 |
| plasma methionine depletion and pharmacokinetic properties in mice of methionine γ-lyase from citrobacter freundii, clostridium tetani and clostridium sporogenes. | pk studies were carried out after a single i.v. administration of 500 and 1000 u/kg by measuring of mgl activity in plasma samples. l-methionine concentration was measured by mass spectrometry. after single i.v. injection of 500u/kg the circulating t1/2 of enzymes in mice varies from 73 to 123min. the auc0-tinf values determined for mgl 500u/kg from c. freundii, c. tetani and c. sporogenes are 8.21±0.28, 9.04±0.33 and 13.88±0.39u/(ml×h), respectively. comparison of pk parameters of three mgl sou ... | 2017 | 28178629 |
| development of a high-throughput method to evaluate serum bactericidal activity using bacterial atp measurement as survival readout. | serum bactericidal activity (sba) assay is the method of choice to evaluate the complement-mediated functional activity of both infection- and vaccine-induced antibodies. to perform a typical sba assay, serial dilutions of sera are incubated with target bacterial strains and complement. the conventional sba assay is based on plating on agar the sba reaction mix and counting the surviving bacterial colony forming units (cfu) at each serum dilution. even with automated colony counting, it is labor ... | 2017 | 28192483 |
| soil type, soil moisture, and field slope influence the horizontal movement of salmonella enterica and citrobacter freundii from floodwater through soil. | pathogens in soil are readily mobilized by infiltrating water to travel downward through the soil. however, limited data are available on the horizontal movement of pathogens across a field. this study used a model system to evaluate the influence of soil type, initial soil moisture content, and field slope on the movement of salmonella enterica serovar newport across a horizontal plane of soil under flooding conditions. three soil types of varying clay content were moistened to 40, 60, or 80% o ... | 2017 | 28221887 |
| the sink as a potential source of transmission of carbapenemase-producing enterobacteriaceae in the intensive care unit. | carbapenemase-producing enterobacteriaceae (cpe) are emerging pathogens that represent a major public health threat. in the university hospital of brussels, the incidence of new patients with cpe rose from 1 case in 2010 to 35 cases in 2015. between january and august 2015, five patients became infected/colonized with cpe during their stay in the same room in the intensive care unit (icu). since the time period between those patients was relatively short and the strains belonged to different spe ... | 2017 | 28239453 |
| carbonyl cyanide m-chlorophenylhydrazine (cccp) reverses resistance to colistin, but not to carbapenems and tigecycline in multidrug-resistant enterobacteriaceae. | background: carbapenems (car), colistin (cst), and tigecycline (tgc) alone or in combination therapy has become the last-resort antibiotics for treating infections caused by multidrug resistant (mdr) bacteria. however, resistance to these reserve antibiotics are increasingly being reported worldwide. hence, the quest to find other agents that will synergistically restore the efficacy of these antibiotics have increased. methods: sixty-three clinical enterobacteriaceae isolates comprising of kleb ... | 2017 | 28261184 |
| impact of revised broad-spectrum cephalosporin clinical and laboratory standards institute breakpoints on susceptibility in enterobacteriaceae producing ampc β-lactamase. | we evaluated the impact of revised clinical and laboratory standards institute (clsi) breakpoints for broad-spectrum cephalosporins (bscs) on the susceptibilities of 1,742 isolates of enterobacter species, serratia marcescens, citrobacter freundii, and morganella morganii. the 2011 clsi criteria for cefotaxime and ceftazidime reduced the rates of susceptibility by 2.9% and 5.9%, respectively. the 2014 clsi criteria for cefepime reduced the rate of susceptibility by 13.9%, and categorized 11.8% i ... | 2017 | 28271652 |
| broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-selex. | conventional cell-selex aims to isolate aptamers to a single unique target bacteria species. we propose a method to isolate single-stranded dna aptamers that have broad reactivity to multiple bacterial targets belonging to different genera. the key of the proposed method is that targets of interest are changed sequentially at each selex round. the general scheme was examined using six bacteria from different genera, escherichia coli, enterobacter aerogenes, klebsiella pneumoniae, citrobacter fre ... | 2017 | 28272554 |
| determination of free polysaccharide in vi glycoconjugate vaccine against typhoid fever. | glycoconjugate vaccines based on the vi capsular polysaccharide directed against salmonella enterica serovar typhi are licensed or in development against typhoid fever, an important cause of morbidity and mortality in developing countries. quantification of free polysaccharide in conjugate vaccines is an important quality control for release, to monitor vaccine stability and to ensure appropriate immune response. however, we found that existing separation methods based on size are not appropriat ... | 2017 | 28282600 |
| draft genome sequence of citrobacter freundii strain a47, resistant to the mycotoxin deoxynivalenol. | here, we present the draft genome sequence of citrobacter freundii strain a47 with a length of 4,878,242 bp, which contains 4,357 putative protein coding genes, including 270 unique genes. this work is expected to assist in obtaining novel gene(s) that code for deoxynivalenol (don) de-epoxidation enzyme(s). | 2017 | 28302773 |
| bacterial cellulose-zinc oxide nanocomposites as a novel dressing system for burn wounds. | bacterial cellulose possesses physical and mechanical properties of an ideal wound dressing material but lack of antimicrobial activity limits its biomedical applications. therefore, in current study, the inherent wound healing characteristics of bacterial cellulose and antimicrobial properties of zinc oxide nanoparticles were combined. the reinforcement (impregnation) of zinc oxide nanoparticles into bacterial cellulose sheets was confirmed through various characterization techniques. the antim ... | 2017 | 28325319 |
| biodegradation of used engine oil by novel strains of ochrobactrum anthropi hm-1 and citrobacter freundii hm-2 isolated from oil-contaminated soil. | used engine oil (ueo) constitutes a serious environmental problem due to the difficulty of disposal off or reuse. ten bacterial strains with biodegradation potential were isolated from ueo-contaminated soil sample using enrichment technique. two strains which exhibited the highest degradation %, 51 ± 1.2 and 48 ± 1.5, respectively, were selected. based on the morphological, biochemical characteristics and 16s rrna sequence analysis, they were identified as ochrobactrum anthropi hm-1 (accession n ... | 2016 | 28330298 |
| multiregional dissemination of kpc-producing klebsiella pneumoniae st258/st512 genotypes in poland, 2010-14. | in 2008-09, the kpc carbapenemase epidemiology in poland was dominated by a klebsiella pneumoniae st258 kpc-2 outbreak in warsaw and its administrative region. the aim of this study was to analyse the situation in 2010-14, with a focus on new outbreaks in other parts of the country. | 2017 | 28333331 |
| evaluation of the β-carba™ test, a colorimetric test for the rapid detection of carbapenemase activity in gram-negative bacilli. | there is an urgent need for accurate and fast diagnostic tests to identify carbapenemase-producing bacteria. here, we have evaluated a novel colorimetric test (the β-carba™ test; bio-rad) to detect carbapenemase-producing gram-negative bacilli from cultured colonies. | 2017 | 28333363 |
| comparative genomic analysis reveals organization, function and evolution of ars genes in pantoea spp. | numerous genes are involved in various strategies to resist toxic arsenic (as). however, the as resistance strategy in genus pantoea is poorly understood. in this study, a comparative genome analysis of 23 pantoea genomes was conducted. two vertical genetic arsc-like genes without any contribution to as resistance were found to exist in the 23 pantoea strains. besides the two arsc-like genes, as resistance gene clusters arsrbc or arsrbch were found in 15 pantoea genomes. these ars clusters were ... | 2017 | 28377759 |
| sequencing and comparative genomics analysis of the inchi2 plasmids pt5282-mpha and p112298-cata and the inchi5 plasmid pynkp001-dfra. | incompatibility group inchi plasmids are important vectors of antibiotic resistance in enterobacteriaceae. in this study, a scheme for typing inchi into five separately clustering subgroups, including previously designated inchi1-3 as well as inchi4-5, was proposed based on sequenced inchi plasmids. the complete nucleotide sequences of the inchi2 plasmids pt5282-mpha and p112298-cata and the inchi5 plasmid pynkp001-dfra from clinical enterobacter cloacae, citrobacter freundii and raoultella orni ... | 2017 | 28390961 |
| sequencing of blaimp-carrying incn2 plasmids, and comparative genomics of incn2 plasmids harboring class 1 integrons. | this work presents the complete nucleotide sequences of p0801-imp from klebsiella pneumoniae, p7121-imp from k. oxytoca, and p17285-imp from citrobacter freundii, which are recovered from three different cases of nosocomial infection. these three plasmids represent the first fully sequenced blaimp-carrying incn2 plasmids. further comparative genomics analysis of all the five integron-carrying incn2 plasmids p0801-imp, p7121-imp, p17285-imp, pjie137, and p34983-59.134kb indicates that they posses ... | 2017 | 28424761 |
| emergence of the colistin resistance gene mcr-1 in citrobacter freundii. | 2017 | 28433744 | |
| characterization of oxa-48-like-producing enterobacteriaceae isolated from river water in algeria. | the spread of carbapenemase-producing enterobacteriaceae (cpe) is a significant problem for healthcare worldwide. the prevalence of carbapenem-resistant enterobacteriaceae (cpe) in water environments in algeria are unknown. the aim of this study was to screen for the presence of cpe isolates in the soummam river in bejaia, algeria. isolates of enterobacteriaceae recovered from twelve samples of river water and showing reduced susceptibility to carbapenems were included in this study. the isolate ... | 2017 | 28486169 |
| morphological analysis of biofilm of peritoneal dialysis catheter in refractory peritonitis patient. | a 66-year-old man undergoing peritoneal dialysis (pd) was admitted to our hospital for treatment of pd-related peritonitis. culture of the pd fluid revealed the presence of citrobacter freundii, and therapy with ceftazidime was started intraperitoneally. the cell count in pd fluid slowly decreased over time during the first 2 weeks of treatment, but increased again on the 14th hospital day. a second culture of the pd fluid revealed the presence of enterococcus species. a switch in antibiotic the ... | 2012 | 28509153 |
| dissemination of bla oxa-370 gene among several enterobacteriaceae species in brazil. | oxa-370 is a recently described oxa-48 variant that has only been described in a few enterobacter spp. and klebsiella pneumoniae isolates. the purpose of this study is to assess the prevalence of oxa-370-producing isolates in carbapenem-nonsusceptible enterobacteriaceae recovered from 28 hospitals from brazil. real-time pcr was used to determine the presence of bla ndm-1, bla kpc-2, bla vim-type, bla ges-type, bla oxa-48-like, and bla imp-type genes. a total of 4,451 enterobacteriaceae were scre ... | 2017 | 28555403 |
| occurrence of plasmid- and chromosome-carried mcr-1 in waterborne enterobacteriaceae in china. | the aim of this study was to investigate the prevalence of the polymyxin resistance gene mcr-1 in enterobacteriaceae from environmental water sources in hangzhou, china. colistin-resistant bacteria were isolated from environmental water samples using an enrichment broth culture method, were screened for mcr-1, and then were analyzed for the location and transferability of mcr-1 isolates positive for mcr-1 were further examined to determine their susceptibility profiles and were screened for the ... | 2017 | 28559252 |
| circulation of blakpc-3-carrying incx3 plasmids among citrobacter freundii isolates in an italian hospital. | colonizations due to carbapenem-resistant enterobacteriaceae (cre) are a source of antimicrobial resistance transmission in health care settings. eleven citrobacter freundii strains producing kpc-3 carbapenemase were isolated from rectal swabs during a 3-year surveillance program. blakpc-3-carrying plasmids were found to belong to the incx3 group in 9 of the 11 strains, and complete nucleotide sequences were obtained for 2 of them. our results highlight the possible role of c. freundii as reserv ... | 2017 | 28559268 |
| emergence of a multidrug-resistant citrobacter freundii st8 harboring an unusual vim-4 gene cassette in poland. | the growing incidence of multidrug-resistant (mdr) bacteria is an emerging challenge in modern medicine. the utility of carbapenems, which are considered 'last-line' agents, is being diminished by the growing incidence of various resistance mechanisms in gram-negative bacteria. a molecular investigation was performed of an mdr carbapenem-resistant citrobacter freundii of sequence type 8 (st8) isolated from a hematology patient with acute myeloid leukemia. | 2017 | 28602727 |
| crystal structure of mutant form cys115his of citrobacter freundii methionine γ-lyase complexed with l-norleucine. | the mutant form of citrobacter freundii methionine γ-lyase with the replacement of active site cys115 for his has been found to be inactive in the γ-elimination reaction of methionine while fully active in the γ-elimination reaction of o-acetyl-l-homoserine and in the β-elimination reaction of s-alk(en)yl-substituted cysteines. in this work, the crystal structure of the mutant enzyme complexed with competitive inhibitor, l-norleucine was determined at 1.45å resolution. at the enzyme active site ... | 2017 | 28602917 |
| an unusual culprit: klebsiella pneumoniae causing septicaemia outbreaks in neonatal pigs? | this study investigated the cause of recent outbreaks of septicaemia in neonatal pigs in australia (victoria and queensland). septicaemia in neonatal pigs is commonly caused by enterotoxigenic e. coli, extraintestinal pathogenic e. coli and beta-haemolytic streptococci. infrequent causes of septicaemia are actinobacillus suis and citrobacter freundii. therefore, it was quite unexpected when klebsiella pneumoniae was isolated in predominant growth from multiple organs of pigs dying of septicaemia ... | 2017 | 28619154 |
| the bactericidal effect of simultaneous titanium oxide on common hospital bacteria. | bacteria prevalence has increased in health centers and hospitals. infection control can decrease the number of bacteria. bacteria cause 90% of nosocomial infections and fungi, viruses, or protozoa are less involved. bacteria control can decrease the number of diseases. the simultaneous titanium oxide (smtio) is a new method of disinfection. this process degrades bacteria by producing hydroxyl radical. the present study was conducted with the aim of analyzing the bactericidal effect of simultane ... | 2017 | 28623574 |
| citrobacter freundii as a cause of acute suppurative thyroiditis in an immunocompetent adult female. | acute suppurative thyroiditis (ast) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. the most common cause of ast is bacterial, and the most common bacteria are staphylococcus aureus, staphylococcus epidermidis, escherichia coli, and klebsiella species. due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. h ... | 2017 | 28631657 |
| imipenem/cilastatin : a reappraisal of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy. | imipenem is an antibacterial agent of the carbapenem class of β-lactams, with a very broad spectrum of activity that includes most gram-negative and gram-positive pathogens, aerobes and anaerobes, and with marked activity against species producing β-lactamases. it is coadministered with cilastatin, a renal dehydropeptidase inhibitor that prevents renal metabolism of imipenem. as initial monotherapy, imipenem/cilastatin provides effective and well-tolerated treatment of moderate to severe infecti ... | 1992 | 28634918 |
| genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in enterobacteriaceae in durban, south africa. | resistance to fluoroquinolones (fq) is being increasingly reported and found to be mediated by efflux pumps, plasmid-mediated quinolone resistance genes (pmqr) and mutations in gyra, gyrb, parc and pare. however, studies reporting on fq resistance mechanisms (fqrm), particularly in africa, are focused mostly on salmonella. this study used a whole-genome-based approach to describe fqrm in forty-eight clinical enterobacteriaceae isolates comprising of klebsiella pneumoniae (n = 21), serratia marce ... | 2017 | 28636609 |
| molecular and microbiological report of a hospital outbreak of ndm-1-carrying enterobacteriaceae in mexico. | to characterize the microbiological, molecular and epidemiological data of an outbreak of carbapenem-resistant enterobacteriaceae (cre) in a tertiary-care hospital in mexico. | 2017 | 28636666 |
| extended-spectrum β-lactamases and plasmid-mediated quinolone resistance in enterobacterial clinical isolates from neonates in tunisia. | this study was conducted to investigate extended-spectrum-β-lactamase (esbl) producing enterobacteriaceae isolates from the center of maternity and neonatology of monastir, tunisia. fourty-six strains out of 283 were found to produce esbl: klebsiella pneumoniae (n = 37), escherichia coli (n = 6), enterobacter cloacae (n = 2), and citrobacter freundi (n = 1). genotyping analysis, using eric2 and rapd, showed that strains were clonally unrelated. pcr amplification followed by sequencing revealed t ... | 2017 | 28648624 |
| monitoring in vitro antibacterial efficacy of 26 indian spices against multidrug resistant urinary tract infecting bacteria. | to screen methanolic extracts of 26 commonly used indian spices against nine species of uropathogenic bacteria (enterococcus faecalis, staphylococcus aureus, acinetobacter baumannii, citrobacter freundii, enterobacter aerogenes, escherichia coli, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa), isolated from clinical samples of a tertiary care hospital for antibacterial activity. | 2014 | 28664089 |
| prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. | objective wound infections following spinal surgery for deformity place a high toll on patients, providers, and the health care system. the prophylactic application of intraoperative vancomycin powder has been shown to lower the infection risk after thoracolumbar decompression and fusion for deformity correction. the purpose of this study was to assess the microbiological patterns of postoperative surgical site infections (ssis) after prophylactic use of vancomycin powder in adult patients under ... | 2017 | 28665245 |
| wastewater is a reservoir for clinically relevant carbapenemase- and 16s rrna methylase-producing enterobacteriaceae. | the aim of this study was to evaluate wastewater for carbapenemase-producing enterobacteriaceae (cpe) and 16s rrna methylase-producing gram-negative bacteria (mpb) and to assess their occurrence following wastewater treatment. wastewater samples were collected between june 2015 and march 2016 in the sewage network of the city of basel (switzerland) from sites located before and after influx of wastewater from the hospital into the sewage network. samples were also obtained from the influent and ... | 2017 | 28668692 |
| gene cloning, characterization, and cytotoxic activity of methionine γ-lyase from clostridium novyi. | the exploitation of methionine-depleting enzyme methionine γ-lyase (mgl) is a promising strategy against specific cancer cells that are strongly dependent on methionine. to identify mgl from different sources with high catalytic activity and efficient anticancer action, we have expressed and characterized mgl from clostridium novyi and compared its catalytic efficiency with the previously studied mgl from citrobacter freundii. the purified recombinant mgl exhibits kcat and kcat /km for methionin ... | 2017 | 28681503 |
| characterization of the complete nucleotide sequences of inca/c2 plasmids carrying in809-like integrons from enterobacteriaceae isolates of wildlife origin. | a total of 18 enterobacteriaceae (17 from gulls and 1 from a clinical sample) collected from australia, carrying inca/c plasmids with the imp-encoding in809-like integrons, were studied. seven plasmids, being representatives of different origins, plasmid sizes, replicon combinations, and resistance genes, were completely sequenced. plasmid pec158, identified in a clinical escherichia coli st752 isolate, showed extensive similarity to type 2 inca/c2 plasmids. pec158 carried none of the blacmy-2-l ... | 2017 | 28696228 |
| honeybee (apis mellifera)-associated bacterial community affected by american foulbrood: detection of paenibacillus larvae via microbiome analysis. | honeybee (apis mellifera l.) workers act as passive vectors of paenibacillus larvae spores, which cause the quarantine disease american foulbrood (afb). we assessed the relative proportions of p. larvae within the honeybee microbiome using metabarcoding analysis of the 16 s rrna gene. the microbiome was analyzed in workers outside of the afb zone (control - afb0), in workers from asymptomatic colonies in an afb apiary (afb1), and in workers from colonies exhibiting clinical afb symptoms (afb2). ... | 2017 | 28698604 |
| insights into a novel blakpc-2-encoding incp-6 plasmid reveal carbapenem-resistance circulation in several enterobacteriaceae species from wastewater and a hospital source in spain. | untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria. however, its role in the spread of antibiotic resistances in the human population remains poorly investigated. we used whole genome sequencing to analyze 25 kpc-2-producing enterobacteriaceae isolates from sewage water collected during a 3-year period and three clinical citrobacter freundii isolates from a tertiary hospital in the same collection ar ... | 2017 | 28702005 |
| arsenic-resistant and plant growth promoting firmicutes and γ-proteobacteria species from industrially polluted irrigation water and corresponding cropland. | the aim of the study was to explore irrigation water polluted with industrial waste and corresponding cropland to screen bacteria for as-detoxification and plant growth promotion. | 2017 | 28708308 |
| characterization of mobile genetic elements carrying vim-1 and kpc-2 carbapenemases in citrobacter freundii isolates in madrid. | carbapenemase producing citrobacter freundii (cpcf) infections are still uncommon in european countries. here we report a molecular study conducted in a tertiary care facility in southern madrid, spain, from 2009 to 2014 to investigate the epidemiology of cpcf. the blaimp-1,blaimp-2,blakpc,blandm,blaoxa-48,blavim-1 and blavim-2 genes were screened by pcr. molecular typing was carried out by pulsed-field gel electrophoresis analysis (pfge) and multilocus sequence typing (mlst). whole genome seque ... | 2017 | 28711315 |
| citrobacter freundii bacteremia: risk factors of mortality and prevalence of resistance genes. | multidrug-resistant strains of citrobacter have emerged, which carry amp-c β-lactamase (amp-c), broad-spectrum β-lactamase, extended-spectrum β-lactamase (esbl), and other resistance mechanisms. these strains are associated with a higher rate of in-hospital mortality. the object of this study is to determine the mortality risk factors, susceptibility pattern to antibiotics, and prevalence of resistance genes in patients with citrobacter freundii bacteremia. | 2017 | 28711438 |
| antimicrobial property of lemongrass (cymbopogon citratus) oil against pathogenic bacteria isolated from pet turtles. | the usage of essential oils as antimicrobial agents is gaining attention. besides, pet turtles were known to harbor a range of pathogenic bacteria while the turtle keeping is a growing trend worldwide.the current study examined the antimicrobial activity of lemon grass oil (lgo) against seven species of gram negative bacteria namely; aeromonas hydrophila, a. caviae, citrobacter freundii, salmonella enterica, edwardsiella tarda, pseudomonas aeruginosa, and proteus mirabilis isolated from three po ... | 2017 | 28747972 |
| ecthyma gangrenosum caused by citrobacter freundii. | a 55-year-old man undergoing chemotherapy for recurrent multiple myeloma presented with a 2-day history of bilateral lower leg rash with pain and oedema. on examination, there were numerous non-palpable retiform pruritic patches over both lower legs. skin pnch biopsy demonstrated a diffuse interstitial neutrophilic infiltrate with necrosis. peripheral blood and skin tissue cultures both isolated citrobacterfreundii, consistent with a rare form of ecthyma gangrenosum. the patient responded with a ... | 2017 | 28751433 |
| multiresistant opportunistic pathogenic bacteria isolated from polluted rivers and first detection of nontuberculous mycobacteria in the algerian aquatic environment. | opportunistic infections constitute a major challenge for modern medicine mainly because the involved bacteria are usually multiresistant to antibiotics. most of these bacteria possess remarkable ability to adapt to various ecosystems, including those exposed to anthropogenic activities. this study isolated and identified 21 multiresistant opportunistic bacteria from two polluted rivers, located in algiers. cadmium, lead, and copper concentrations were determined for both water samples to evalua ... | 2017 | 28771154 |