Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| immunogenetics of graves' ophthalmopathy. | we have performed an immunogenetic analysis of 53 patients with severe graves' ophthalmopathy, 51 patients with graves' disease but little or no clinically apparent eye disease, and 90 controls. the distribution of restriction fragment length polymorphisms was analysed in the three groups, using probes for the hla-dq alpha and dr beta regions, the t-cell receptor c alpha, v alpha, c beta and j gamma genes and the immunoglobulin gene switch regions, s alpha and s mu. there was no abnormal distrib ... | 2010 | 2908181 |
| reducing the illegal sale of cigarettes to minors. | this study reports on an effort to stop the illegal sale of cigarettes to minors. in santa clara county, calif, 412 stores and 30 vending machines were visited by 18 minors aged 14 through 16 years with the intent to purchase cigarettes; they were successful at 74% of the stores and 100% of the vending machines. after an aggressive six-month campaign using communitywide media, direct merchant education, contact with the chief executive officers of chain stores and franchise operations owned by m ... | 1989 | 2908999 |
| effect of aging on populations of estrogen receptor-containing cells in the rat uterus. | estrogen receptor-containing cells were identified in uteri of mature and senescent rats by means of quantitative autoradiography. cell numbers and density were assessed in the various uterine layers. it was determined that despite decreases in receptor concentrations in endometrium, endometrial stroma, myometrium, and epithelium, no significant cell loss occurred in any region. receptor content per cell clearly decreased with age in the endometrial stroma, while only in the myometrium was there ... | 1989 | 2909390 |
| protective role of serum antibody in immunity to chlamydial genital infection. | female guinea pigs were injected intraperitoneally with pooled immunoglobulin derived from animals immunized to the chlamydial agent of guinea pig inclusion conjunctivitis. genital infections in animals receiving pooled immunoglobulin from immune animals were markedly decreased with regard to the number of inclusions detected compared with control animals. these data indicated that serum-derived antibody was able to provide a degree of protection against a chlamydial genital tract infection. | 1989 | 2909492 |
| newer techniques of laryngeal reinnervation. | we relate the experience obtained in the use of the right superior laryngeal nerve (motor branch)--cricothyroid muscle pedicle flap in dogs in an attempt to reinnervate the right posterior cricoarytenoid muscle (pca). the right vocal cord was paralyzed by severance and removal of 2.5 cm of the right recurrent laryngeal nerve. evaluation 6 months postoperatively revealed the vocal fold remobilization on the right side to have an average of about one half the mobility of the left, normal side. aft ... | 1989 | 2910195 |
| decreased cardiac toxicity of doxorubicin administered by continuous intravenous infusion in combination chemotherapy for metastatic breast carcinoma. | two hundred and seventy-four consecutive patients with measurable metastatic breast cancer, without prior exposure to cytotoxic agents were treated with tamoxifen, 5-fluorouracil, doxorubicin, and cyclophosphamide (fac). the initial 133 patients received doxorubicin by bolus iv administration and for the next group of 141 patients doxorubicin was administered via a central venous catheter over a 48-hour (79 patients) or 96-hour (62 patients) continuous infusion schedule. patients treated with bo ... | 2009 | 2910423 |
| dysplastic nevi. markers for increased risk for melanoma. | a total of 452 white patients, classified into four dysplastic nevi groups, were followed prospectively by repetitive, complete cutaneous examinations using total-body photographs taken on entry into the study. sixteen patients (3.5%) developed 18 newly diagnosed malignant melanomas (mm) during an average follow-up period of 27 months. twelve of the 18 mm were in situ, and all of the six primary invasive mm diagnosed prospectively in this follow-up were less than 0.89 mm in breslow thickness, im ... | 2010 | 2910446 |
| polyclonal anti-idiotypes influence macrophage chemotaxis in coxsackievirus-induced murine myocarditis. | investigation into the mechanism(s) whereby monocytes-macrophages are mobilized to the myocardium of coxsackievirus (cvb3)-infected mice was approached by assessing the role of anti-idiotypic antibodies against specific antiviral igg molecules. balb/c mice preinoculated with polyclonal anti-idiotypic, syngeneic antibodies resulted in significantly decreased myocarditis after virus challenge. on the other hand, oil-induced peritoneal exudate cells obtained from virus-exposed animals demonstrated ... | 1989 | 2911021 |
| cocaine--the deadliest addiction. | 2010 | 2911405 | |
| polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: possible effect on mitochondrial membranes. | the polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. the presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, suggesting a possible role of these molecules in the transport of the precursor of ornithine carbamoyltransferase into mitochondria, by the formation and/or stabilization of mitochon ... | 1989 | 2912450 |
| risk of renal dysfunction in critically ill trauma patients receiving aminoglycosides. | 2010 | 2912664 | |
| failure of vitamin e to protect the retina against damage resulting from bright cyclic light exposure. | cumulative light-mediated damage to the retina over a long time period may be involved in the development of age-related retinopathies. light is thought to produce retinal damage by initiating autoxidative reactions among the molecular components of the retina. experiments were therefore conducted (1) to confirm that long-term differences in cyclic light intensity affect the rate of age-related photoreceptor cell loss from the retina; and (2) to determine whether the antioxidant, vitamin e, is a ... | 1989 | 2912912 |
| aplysia synaptosomes. i. preparation and biochemical and morphological characterization of subcellular membrane fractions. | we prepared and characterized subcellular membrane fractions from the cns of aplysia californica that are enriched in isolated nerve terminals (synaptosomes). ganglia were homogenized in 1.1 m sucrose and fractionated on a 2-step sucrose gradient, yielding 50 micrograms protein/animal in the synaptosomal fraction (p3), which was enriched 3-fold in plasma membrane as compared with the initial homogenate. quantitative morphometry of electron micrographs revealed that p3 contained 25% intact synapt ... | 1989 | 2913212 |
| leads from the mmwr. measles prevention: supplementary statement. | 2010 | 2913378 | |
| improved sexual function in hemodialysis patients on recombinant erythropoietin: a possible role for prolactin. | as it was reported that correction of anemia in long-term hemodialysis patients by recombinant human erythropoietin (r-huepo) is associated with improved sexual function, we conducted the present study to further delineate the mechanism(s) by which this is brought about. serum prolactin, testosterone, and parathyroid hormone (pth) levels were followed during 4 months of r-huepo therapy. within 4 months of treatment with r-huepo, hematocrit values rose from 23.7 +/- 1.2 to 35.7 +/- 0.2% and hemog ... | 1989 | 2914405 |
| [flexion-distraction injuries of the thoracolumbar spine with complete pancreatic rupture. description of a case]. | a case is reported of an unstable fracture dislocation of the thoracolumbar vertebral column combined with complete rupture of the pancreas. this combination of injuries is rarely encountered but is dangerous in severely injured patients. rapid and decisive operative treatment of both injuries should be performed, whereby adequate treatment of the pancreatic rupture has the highest priority. | 2010 | 2916133 |
| the artificial sphincter (as-800). experience in children and young adults. | from reviewing our experience in the application of the as-800 sphincter for the management of incontinence in children, we conclude that implantation is indicated after conservative and less invasive therapy has been attempted. the bladder neck is the site of choice for cuff placement in children. primary deactivation and moderate or low reservoir pressures (61 to 70 and 71 to 80 cm h2o) are indicated, especially in patients with previous bladder neck surgery or an inadvertent bladder neck inju ... | 2010 | 2916269 |
| clinical experience with controlled expansion cylinders. the ams 700 cx inflatable penile prosthesis. | device manufacturers continue to look for modifications in design to achieve specific objectives directed at improving overall reliability. changes in design that do not address this extremely significant concern, namely, device reliability, fail in their commitment toward improvement in patient satisfaction. one of the most effective ways to assess the benefits provided by any change in device design is through the clinical trial and study group method, utilizing a large number of implanting su ... | 2010 | 2916279 |
| sex therapy for the penile prosthesis recipient. | in conclusion, the evidence for technical success of the penile prosthesis is clear, but more detailed follow-up studies suggest that a large minority of patients and partners fail to achieve sexual satisfaction. if the goal of surgery is to restore sexual frequency, variety, and pleasure to optimal levels, an integrated treatment program that incorporates sex therapy may be more successful than implantation alone. the type of sex therapy required depends on the risk factors present for postsurg ... | 2010 | 2916282 |
| aids estimates. | 2010 | 2916352 | |
| the protective effect of thromboxane synthetase inhibition on renal function in systemic sepsis. | to study the role of thromboxane in systemic sepsis and renal failure, peritonitis was induced surgically in 22 sheep, leading to local and systemic sepsis. a selective thromboxane synthetase inhibitor, u63,557a (upjohn co, kalamazoo, mi) was given before surgery in five animals and 30 minutes after surgery in five animals. a typical picture of volume-loaded, normotensive, vasodilated septic shock developed in all animals. twenty four hours after induction of sepsis, the control group showed a m ... | 1989 | 2916566 |
| ternary representation of trivariate data. | a new fast trivariate display technique based on the ratio of three measured variables and of relative cell number, obtained from flow cytometric measurements, is described. | 2010 | 2917477 |
| ph-dependent uptake and macrofilaricidal effects of chloroquine on adult filarial parasites in vitro. | uptake and macrofilaricidal effects of chloroquine (cq) and other aminoquinolines were found to be highly ph dependent in brugia pahangi, acanthocheilonema viteae, onchocerca volvulus, and dirofilaria immitis. using [3h]cq, it was found that all of the parasites took up more drug under alkaline conditions (rpmi 1640 at ph 8.4) than in neutral (ph 7.4) or acidic (ph 6.8) media. differences were seen in the amount of drug taken up among the filariae studied. b. pahangi and a. viteae took up 7 time ... | 1989 | 2917628 |
| rapid detection of cutaneous herpes simplex virus infection with the polymerase chain reaction. | a simple and specific method for detecting herpes simplex virus infection in routinely processed paraffin-embedded biopsy specimens is described. dna is extracted from paraffin blocks, and subjected to dna amplification with the polymerase chain reaction. after 40 rounds, an amplified band can be detected after agarose gel electrophoresis and ethidium bromide staining. this band is specific for herpes simplex virus, because tissues infected with related viruses do not give this amplified band. w ... | 2010 | 2918243 |
| diurnal variations in pain perception and thermal sensitivity. | pain and thermal sensitivity thresholds in healthy volunteers were examined for diurnal variations. the subjects were 11 men aged between 22 and 27 years (means = 23.5, s.d. = 1.5). data were collected for 2 days, with 7 measurements per day. to ensure the pain specificity of the results the subliminal modality, i.e., thermal sensitivity thresholds to warm and cold stimuli, was investigated in addition to the threshold for perception of heat pain. assessments were made on the right hand and foot ... | 2010 | 2919090 |
| [regional differences in the use of cholecystectomy in denmark during the period 1977-1985]. | in a register-based study of all cholecystectomized patients in denmark during the period from 1977-85 (37,048 patients) an account is given of the regional variations observed in connection with the intervention. the cholecystectomy operation is sub-divided into four types of operation dependent on whether the intervention is merely a matter of cholecystectomy or it involves the choledocus, the duodenum, the small intestine or other organs. the variation analysis is based on a division of the c ... | 2010 | 2919465 |
| right atrial cardioplegia: a safe procedure for myocardial protection. | 2010 | 2919927 | |
| 'keeping up-to-date with tooth notation'. | 2010 | 2920126 | |
| paradoxical effect of respiration on ventricular rate in atrial fibrillation. | 1. in 50 subjects with atrial fibrillation we have attempted to demonstrate variation of ventricular rate with respiration, as evidence of cardioregulatory reflex activity. 2. the electrocardiogram was recorded for 3 min during spontaneous respiration. the presence of respiratory variation of r-r intervals was analysed by multiple regression against a cosine function (cosinor analysis), making it possible to determine the phase of respiration when the intervals were longest. 3. variation in vent ... | 2010 | 2920528 |
| hepatic structural correlates of liver fibrosis: a morphometric analysis. | liver fibrosis is an important feature of many liver diseases, and the assessment of fibrosis is essential for diagnosis and prognosis. liver needle biopsy, however, tends to sample preferentially the soft parenchyma, which poorly reflects the true extent of fibrosis. therefore, we have searched for capsule and parenchymal features that are correlated with the fibrosis. to test for these correlations, we used a morphometric analysis of a rat model of liver fibrosis. we demonstrated that, of the ... | 1989 | 2920817 |
| degradation of type ix collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells. | the degradation of type ix collagen, a minor collagen in cartilage, was examined by treatment with three different types of matrix metalloproteinases (mmps) purified from the culture medium of rheumatoid synovial cells. neither mmp-1 (collagenase) nor mmp-2 (so-called 'gelatinase') could digest type ix collagen, but mmp-3 (stromelysin) readily degraded it into smaller fragments. this suggests that mmp-3 may be responsible for the pathological degradation and/or normal turnover of type ix collage ... | 1989 | 2920840 |
| seminal prolactin and its relationship to sperm motility in men. | semen assessment and levels of serum and seminal plasma prolactin (prl) were determined in 81 men. in subjects with both normal sperm concentrations and normal sperm motility, the levels of serum and seminal plasma prl were 14.7 +/- 1.48 and 10.0 +/- 1.05 ng/ml (mean +/- standard error of the mean, sem, p less than 0.05), respectively. this difference is not observed either in subjects with polyzoospermia with normal sperm motility, or in those with oligozoospermia. serum prl was higher in azoos ... | 2010 | 2920849 |
| health care entrepreneur's key to success: break the mold. | 2009 | 2921025 | |
| sensitivity of campylobacter pylori to colloidal bismuth subcitrate. | 1989 | 2921366 | |
| misunderstanding possible in scope of work. | 2010 | 2922197 | |
| the rediscovery of the national health program by the democratic party of the united states: a chronicle of the jesse jackson 1988 campaign. | this report chronicles the major developments in the jesse jackson 1988 campaign and their consequences for the establishment of a national health program in the united states. it describes the characteristics of the jackson 1988 campaign, and the set of events that led to the rediscovery of the national health program by the democratic party of the united states. | 2010 | 2925296 |
| functional significance of the kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. | blood coagulation can be initiated when factor vii or viia, a plasma protease, binds to its essential cofactor, tissue factor (tf), and proteolytically activates factors ix and x, triggering a cascade of events which eventually leads to the formation of thrombin and a fibrin clot. plasma contains a lipoprotein-associated coagulation inhibitor (laci) which inhibits activated factor x (xa) directly and, in a xa-dependent way, inhibits vii(a)/tf activity, presumably by forming a quaternary xa/laci/ ... | 2010 | 2927510 |
| knowledge about suicide as a function of experience. | 2010 | 2928057 | |
| opportunities for lay midwifery practice. | 2010 | 2929822 | |
| internal medicine in the national resident matching program 1978-1989. | 2010 | 2930105 | |
| calcific shoulder periarthritis (tendinitis) in adult onset diabetes mellitus: a controlled study. | two groups, one of 824 adult diabetics and one of 320 age and sex matched non-diabetics, were examined for abnormal glucose metabolism and calcifications on anteroposterior shoulder x rays. two hundred and sixty two (31.8%) of the diabetics had shoulder calcification compared with 33 (10.3%) of the control group, with a preponderant localisation in the right shoulder. diabetes of long duration treated with insulin for a long time was associated with a larger percentage of shoulder calcifications ... | 2010 | 2930276 |
| release of atrial natriuretic peptide by atrial distension. | a heterologous radioimmunoassay was used to measure the concentration of immunoreactive atrial natriuretic peptide (ianp) in plasma from the femoral artery of eight chloralose anaesthetized dogs. mitral obstruction which increased left atrial pressure by 11 cmh2o increased plasma ianp from 97 +/- 10.3 (mean +/- se) to 135 +/- 14.3 pg/ml. pulmonary vein distension increased heart rate but did not increase plasma ianp. bilateral cervical vagotomy and administration of atenolol (2 mg/kg) did not pr ... | 1985 | 2931169 |
| [experimental study of oral administration of streptococcal preparation "ok-432". the 6th report: its effect on in vivo anti-tumor immunity of the mice with transplanted cecal tumor]. | 2010 | 2932509 | |
| [nutrition in the etiology of breast cancer. results of a survey in austria]. | 2010 | 2934651 | |
| [biological functions and time--the loose coupling mechanism of molecular machines]. | 2010 | 2934765 | |
| thyroxine induced transformation in sarcoplasmic reticulum of rabbit soleus and psoas muscles. | the properties of the sarcoplasmic reticulum membranes isolated from slow-twitch type i soleus and fast-twitch type ii psoas muscles of control and thyroxine treated rabbits were comparatively studied. membrane yield, maximal calcium storing capacity, atp-supported calcium uptake, calcium-dependent atpase activity and calcium-dependent phosphoprotein formation were found to be 3-10 fold higher in psoas than in soleus preparations. membrane yield, calcium-dependent atpase activity, atp-supported ... | 1985 | 2934902 |
| fixed drug erythema due to two unrelated drugs. | 2010 | 2935136 | |
| cellular and vessel wall morphology of cerebral cortical arterioles after short-term diabetes in adult rats. | microvascular pathology is one of the major problems associated with prolonged diabetes mellitus. the purpose of the present study was to determine if anatomical cellular pathology of the cerebral cortical microvessels could be detected very early after the onset of a streptozotocin-induced model of diabetes. male rats at age 14-16 weeks were hyperglycemic (greater than 250 mg/dl) for 4 weeks prior to scanning and transmission electron microscopic analysis of the external and internal cell and v ... | 1985 | 2935212 |
| [involvement of the first 2 lumbar roots and paralysis of the abdominal-genital nerves. clinical and electrical data]. | we report two observations of ilio-hypogastric and ilio-inguinal palsy. in both cases, an inguino-scrotal pain occurs just after low back effort. clinically, we observed an infero-lateral 'pseudo-eventration' and trochantero-inguino-scrotal hypoesthesia in the first patient and an inguino-scrotal hypoesthesia in the second. the emg recording shows an isolated, severe or total peripheric denervation of the inferior part of lateral abdominal muscles, associated in one case with a partial denervati ... | 2010 | 2937117 |
| [various indices of compensatory reactions of placental vessels in different forms of diabetes mellitus in pregnant women]. | 2010 | 2937317 | |
| [immunologic functions of kupffer cells]. | 2010 | 2937390 | |
| cnbr cleavage of the light chain of human complement factor i and alignment of the fragments. | the light chain and heavy chain of reduced and alkylated human complement factor i were purified by high-pressure gel-permeation chromatography. cnbr cleavage of factor i light chain yielded four major fragments, which were purified by gel filtration. n-terminal sequence analysis of the cnbr-cleavage fragments allowed identification of 200 of the approx. 240 amino acid residues of the light chain. an alignment is proposed, based on sequence analysis of peptides obtained after cleavage at arginin ... | 1986 | 2937401 |
| the role of immunoglobulin e receptors in allergic diseases. | recent studies presented evidence that subpopulations of lymphocytes, monocytes and eosinophils carry immunoglobulin (ige)-specific membrane receptors which differ from the classical fc epsilon-receptors on basophil granulocytes and mast cells. the analysis of ige-receptor interactions with various cells has led to important insights as to the requirements of ige-antibody regulations. in addition, the membrane biochemical mechanisms in the induction of mediator release became better understood. ... | 2010 | 2937412 |
| effects of heparan sulfate removal on attachment and reattachment of fibroblasts and endothelial cells. | human skin fibroblasts and calf aorta endothelial cells were grown as tissue culture monolayers in the presence of [35s]sulfate in order to label the glycosaminoglycan portions of proteoglycans for investigation of their role in cell attachment. the [35s]glycosaminoglycans were then selectively removed from the cell monolayers by the addition of various glycosaminoglycan-degrading enzymes. as previously described, in contrast to trypsin treatment none of these enzymes removed any cells from the ... | 1986 | 2937448 |
| chromophore/protein interaction in bacterial sensory rhodopsin and bacteriorhodopsin. | retinal analogues with altered conjugated double bond systems or altered stereochemistry were incorporated into the phototaxis receptor sensory rhodopsin (sr) and the light-driven proton pump bacteriorhodopsin (br) from halobacterium halobium. wavelength shifts in absorption ("opsin shifts") due to analogue interaction with the protein microenvironment demonstrate that the same overall electrostatic and steric properties of the retinal binding-site structures exist in both proteins despite their ... | 1986 | 2937462 |
| cultured human endothelial cells synthesize a plasma membrane protein complex immunologically related to the platelet glycoprotein iib/iiia complex. | we have previously demonstrated that endothelial cells synthesize a plasma membrane protein indistinguishable from platelet glycoprotein (gp) iia. the present study provides evidence for a further analogy between the platelet and the endothelial cell membrane by showing that cultured endothelial cells also synthesize a membrane protein complex immunologically related to the platelet gp iib/gp iiia complex. this evidence is based on the following observations: (1) c17, a murine monoclonal antipla ... | 1986 | 2937471 |
| serum beta-endorphin in primary fibromyalgia syndrome: a controlled study. | serum beta-endorphin was assayed without knowledge of study subject category in 44 consecutive patients with primary fibromyalgia syndrome, 3 patients with rheumatoid arthritis (ra), and 30 normal controls, all females. mean serum beta-endorphin levels were 81 +/- 28 pg/ml in patients with fibromyalgia, whereas those in normal controls and patients with ra were 73 +/- 17 pg/mg and 73 +/- 18 pg/ml, respectively. these differences were not statistically significant. serum beta-endorphin levels did ... | 2010 | 2939238 |
| a follow up of t-cell subsets and of anti-m. leprae antibody titer as measured by the fla-abs test in melanesian leprosy patients under polychemotherapy. | melanesian leprosy patients from new caledonia were studied for the following parameters during the course of polychemotherapy: peripheral blood t-cell subsets, as identified in an immunofluorescence assay with monoclonal antibodies okt3 ("pan-t"), okt4 ("helper/inducer"), and okt8 ("cytotoxic-suppressor"), and anti-mycobacterium leprae antibodies in the serum, as measured by the fluorescent leprosy antibody absorption test. a group of melanesian healthy subjects with no known exposure to m. lep ... | 1986 | 2940306 |
| [pathogenetic aspects of schönlein-henoch disease]. | 2010 | 2940752 | |
| [risk factors in the epidemiology of dysentery]. | the general tendency of a decrease in the morbidity rates of dysentery induced by shigella sonnei and shigella flexneri (separately) from monday to the end of the week (saturday-sunday) has been revealed, and at the same time the "infection risk" for both kinds of salmonellosis has been found to fall on the last days of the week (friday-sunday). | 1986 | 2940778 |
| dose-related effects of synthetic human beta-endorphin and naloxone on fed gastrointestinal motility. | in humans, plasma beta-endorphin levels rise during application of acute stressful stimuli (vertigo, cold pain, and transcutaneous electrical stimulation) that induce gut motor disturbances. whereas it is possible that circulating beta-endorphin participates in the mediation of these central effects on gut motility, its role cannot be established solely on the basis of changes in plasma levels. therefore, we designed the present study to investigate 1) the dose-related effects of intravenous syn ... | 1986 | 2942039 |
| isolation, characterization and utilization of the fifth component (c5) of porcine complement. | the fifth component (c5) of porcine complement was isolated in immunochemically pure, homogeneous and native form. the isolated component was characterized, it has a molecular weight of 187,000 (under non-reducing conditions) and two non-identical chains of 112,000 and 76,000 under reducing conditions, respectively. the isolated c5 can be used for the detection of the c5b receptors on murine macrophages. our findings are in good agreement with the results obtained using a rabbit and a human mode ... | 1986 | 2943607 |
| ultracytochemical evidence for a proton-pump adenosine triphosphatase in chick osteoclasts. | the distribution of mg++-atpase in osteoclasts along the endosteal surface of the chick tibia was investigated by neutral and alkaline ph cytochemical methods at the electron-microscopic level. reaction product was observed in mitochondria, cytoplasmic vesicles, and ruffled-border membrane. levamisole, ouabain, and vanadate did not affect the enzymatic activity. para-chloromercuribenzoic acid (pcmb) prevented staining of mitochondria, ruffled border, and most cytoplasmic vesicles. tri-n-butyltin ... | 1986 | 2944590 |
| [preliminary study on the processing of isatis tinctoris]. | 2010 | 2944655 | |
| [effects of cycleanine dimethobromide on heart conduction system]. | 1985 | 2945367 | |
| interaction studies in mice of sch 29851, a potential non-sedating antihistamine, with commonly used therapeutic agents. | sch 29851 was studied for its ability to interact with selected drugs used in man. the non-sedating antihistamine terfenadine and the sedating antihistamine diphenhydramine were also studied for comparison. sch 29851 at 80 mg/kg po in mice, a dose about 50 times its ed50 for blocking histamine-induced paw edema in the same species, potentiated the anticonvulsant effects of diazepam. at the high dose of 320 mg/kg po, about 80 times its ed50 for antihistamine effects, sch 29851 potentiated the abi ... | 1986 | 2945410 |
| pharmacokinetics and effect on blood pressure of doxazosin in normal subjects and patients with renal failure. | the antihypertensive efficacy and pharmacokinetics of a single 1 mg oral dose of doxazosin were investigated in five healthy male volunteers, six patients with renal failure not on hemodialysis, and four patients with end-stage renal failure studied between two hemodialyses. the dialyzability of doxazosin was studied in five patients. the maximum fall in blood pressure of both volunteers and patients occurred between 4 and 8 hours. in four of five volunteers the blood pressure had returned to ba ... | 2010 | 2945688 |
| effect of mononuclear cell factors on calcium transport in sarcoplasmic reticulum vesicles. | the effect of supernatants from cultures of mitogen-stimulated human mononuclear cells on calcium transport by sarcoplasmic reticulum was examined. calcium transport was assayed by measuring the time course of calcium accumulation by sarcoplasmic reticulum incubated with supernatants from stimulated mononuclear cells was 20% less than that by vesicles exposed to control supernatants (p less than 0.001). in contrast, no difference in calcium-dependent atpase activity was noted between vesicles in ... | 1986 | 2946307 |
| structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model. | physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ... | 1986 | 2946570 |
| structure-activity relationships of sex steroid analogs determined in vitro in a thyroid hormone-responsive membrane ca2+-atpase model. | physiological concentrations of l-t4 were found previously to stimulate ca2+-atpase activity in vitro in reticulocyte membranes from female rabbits and to inhibit this enzyme in reticulocyte membranes from males. in these previous studies, preincubation of intact cells or ghosts with testosterone (5 x 10(-11) m) converted female-source reticulocyte membranes to male-type responsiveness to thyroid hormone (inhibition of ca2+-atpase activity). preincubation of reticulocyte membranes with 17 beta-e ... | 1986 | 2946570 |
| relationship among function, phenotype, and specificity in primary allospecific t cell populations: identification of phenotypically identical but functionally distinct primary t cell subsets that differ in their recognition of mhc class i and class ii allodeterminants. | the goal of the present study was to evaluate the relationship among function, lyt phenotype, and mhc recognition specificity in primary allospecific t cell populations. by using lyt-2+ and l3t4+ t cells obtained from the same responder populations, we assessed the ability of t cells of each phenotype to generate cytotoxic effector cells (ctl) and il 2-secreting helper t cells in response to either class i or class ii mhc allodeterminants. it was found that a discordance between lyt phenotype an ... | 2010 | 2946773 |
| docosahexaenoic acid status of preterm infants at birth and following feeding with human milk or formula. | the docosahexaenoic acid (dha) status of preterm infants (less than 32 wk gestation) was measured as the molar percent of dha in individual red blood cell phospholipids: 1) in cord venous blood immediately following delivery, 2) after infants were receiving greater than 60 kcal x kg x day of energy from oral-gastric feedings, and 3) at a mean of 7 wk later. infants on full feeding received either preterm human milk or formula. the dha concentration of all phospholipid classes declined between bi ... | 1986 | 2947455 |
| [treatment of chronic renal failure with traditional chinese medicine. follow-up of 90 cases]. | 2010 | 2947714 | |
| [effects of my-5116 on experimental animal models of type i-type iv allergic reactions and the formation of ige antibody]. | the effects of a new anti-allergic agent, my-5116: isoamyl 5,6-dihydro-7,8-dimethyl-4,5-dioxo-4h-pyrano [3,2-c] quinoline-2-carboxylate, on experimental animal models of type i approximately type iv allergic reactions and the formation of ige antibody were investigated. my-5116 administered intraperitoneally at doses of 30 and 100 mg/kg suppressed significantly the homologous pca in guinea pigs. my-5116 administered intraperitoneally at the dose of 100 mg/kg also suppressed significantly the het ... | 1986 | 2947841 |
| [a new procedure for the biological denitrification of ground water]. | 2010 | 2950354 | |
| the mmpi and psychological factors in chronic low back pain: a review. | the minnesota multiphasic personality inventory (mmpi) is widely used in the psychological assessment of patients with chronic low back pain (lbp). patients' profiles have been used in a number of ways: in attempts to discriminate between cases; as predictors of both medical treatment and pain management program outcomes; and in attempts to assess degree of disability. studies reviewed here indicate that the concept of psychological etiology of chronic lbp, despite widespread use, has failed to ... | 2010 | 2950363 |
| [various factors affecting the level of detection of schizophrenics]. | having studied the population of the schizophrenic patients registered at the psychoneurological dispensary of samarkand (n = 678) the authors have revealed that the identification of patients depends on both age/sex structure of the general population and the educational level. it has been found that underdetection of schizophrenics in samarkand is mainly accounted for by favourable cases of schizophrenia in particular in the following social groups: in young people under 19 years; in people wi ... | 2010 | 2950691 |
| determinants of salvage of jeopardized myocardium after coronary thrombolysis. | coronary thrombolysis is an attractive approach for salvaging jeopardized, ischemic myocardium. the advent of second- and third-generation clot-selective thrombolytic agents will make this approach safer and more widely applicable in the future. however, residual stenoses and reocclusion are common after the thrombolytic therapy. in addition to thrombolysis, future management of coronary thrombosis may include adjunctive pharmacologic therapy such as calcium-channel antagonists, beta-blockers, o ... | 2010 | 2951009 |
| brain beta-endorphin and spinal-cord enkephalin concentrations in experimental arachnoiditis. | arachnoiditis was produced experimentally in male albino icr mice by intrathecal injection of meglumine iocarmate . a control group received intrathecal injection of an electrolyte solution resembling csf. eight weeks after injection, the brains and spinal cords were removed for brain beta-endorphin and spinal cord met-enkephalin measurement by radioimmunoassay, and the dural sacs were removed for histologic examination to confirm the presence or absence of arachnoiditis. brain beta-endorphin co ... | 2010 | 2951348 |
| neurosecretion of human hypothalamic immunoreactive beta-endorphin: in vitro regulation by dopamine. | an in vitro perifusion system was used to investigate immunoreactive beta-endorphin (beta-end-i) release from adult human hypothalami in response to dopamine (da) and the da receptor antagonist haloperidol (hal). administration of a 1 microm pulse of da consistently elicited a mean (+/- se) 88 +/- 9% increase (p less than 0.05, n = 5) in beta-end-i release, whereas 1 microm hal had no effect. administration of 1 microm da during three perifusions in which 1 microm hal was added to the medium fai ... | 1987 | 2951610 |
| [in vitro development of blastema cells in axolotl limb regeneration: effect of insulin and nerve extracts on cellular proliferation]. | for the purpose of investigating the nature of the nervous factor which controls cell proliferation in limb blastema of newts, we have cultured primary mesenchymous cells from limb blastemas of axolotl. the cultures were carried out in petri dishes (primaria, falcon) with a basal medium with contained diluted mem supplemented with hormones (insulin, somatotropin, hydrocortisone and thyroxine). in this medium, the cells disperse from the explant from the 4th day of culture and begin to divide fro ... | 2010 | 2952210 |
| malignant hyperthermia and the dental practitioner. | 2010 | 2952234 | |
| abnormal degradation of erythrocyte membrane proteins in down's syndrome. | 2010 | 2953697 | |
| reversible harmless interruption of testicular blood supply in the ram. | an effective method of interrupting testicular blood flow temporarily and repeatedly in the ram has been developed. blockade of flow has been achieved mechanically by an inflatable occluder placed around the testicular artery at the level of the spermatic cord. the effect of the blockade on total testicular blood supply was investigated using doppler flowmetry and a percutaneous xenon-133 injection method. with both approaches, the blood flow changes after inflation or deflation of the occluders ... | 1987 | 2953703 |
| [a case of severe colitis with positive hemocultures for shigella flexneri]. | 1987 | 2954108 | |
| [involvement of the brain stem at the onset of legionnaires' disease]. | 2010 | 2954126 | |
| balloon-dilatable arterial banding prosthesis: experimental study. | two arterial banding prostheses were developed that could be dilated by an intraluminal balloon dilator. one prosthesis consisted of radiopaque umbilical tape with a pleat secured by four 8-0 silk sutures thinly coated with silicone type a medical adhesive. this design was used to band the main pulmonary artery in five dogs, the subclavian artery in five, and the aorta in one. the second prosthesis, a stainless steel fatigued helix encased in a siliconized shield, was used to band the main pulmo ... | 1987 | 2954182 |
| clinical significance of u1-rnp immune complexes in mixed connective tissue disease and systemic lupus erythematosus. | we measured u1-rnp: anti-u1-rnp immune complexes (u1-rnp ics) in patients with mixed connective tissue disease (mctd) and systemic lupus erythematosus (sle) to examine the clinical significance of circulating u1-rnp ics. the level of u1-rnp ics in 11 patients with mctd was significantly higher than that in 22 normal subjects and there was a close correlation between the level of u1-rnp ics and the clinical disease activity index of mctd. in contrast, the level of u1-rnp ics in 31 patients with s ... | 2009 | 2954202 |
| clinical significance of u1-rnp immune complexes in mixed connective tissue disease and systemic lupus erythematosus. | we measured u1-rnp: anti-u1-rnp immune complexes (u1-rnp ics) in patients with mixed connective tissue disease (mctd) and systemic lupus erythematosus (sle) to examine the clinical significance of circulating u1-rnp ics. the level of u1-rnp ics in 11 patients with mctd was significantly higher than that in 22 normal subjects and there was a close correlation between the level of u1-rnp ics and the clinical disease activity index of mctd. in contrast, the level of u1-rnp ics in 31 patients with s ... | 2009 | 2954202 |
| the nature and development of steroid hormone receptors. | 2010 | 2954846 | |
| [fansidar-induced maculopathy and dermatitis exfoliativa]. | 2010 | 2955547 | |
| [genetic characteristics and protective properties of neamin-resistant mutant salmonella typhimurium and s. dublin of the nea(r) str(s) and nea(r) str(r) 500 classes]. | the genetic analysis of attenuated mutants, class nea(r) str(s), with the use of bacteriophage p 22 has shown that mutation rendering the mutants resistant to neamine is localized in gene nea a. in experiments with the intraperitoneal infection of mice, the appearance of this mutation in s. typhimurium and s. dublin virulent strains has been found to lead to the decrease of virulence in 100% of clones. on the basis of the data obtained in this investigation, region str-spc in s. typhimurium and ... | 1987 | 2955615 |
| the classic. concept of disability. by earl d. mcbride. 1963. | 2010 | 2955987 | |
| [role of laparoscopic examination in the diagnosis and control of treatment results in early and less advanced forms of endometriosis]. | 2010 | 2956633 | |
| [role of the m. canis carrier state of healthy animals in the epidemiology of zoonotic microsporum infection]. | 1987 | 2956788 | |
| possible cellular mechanism for cerebral vasospasm after experimental subarachnoid hemorrhage in the dog. | this study was undertaken to examine some of the cellular ionic mechanisms responsible for the cerebral vasospasm that occurs as a consequence of subarachnoid hemorrhage (sah). after cisternal injection of autologous blood we documented spasm of the basilar artery upon angiography from 4 to 7 d postictus in six dogs. when these basilar arteries were isolated we observed marked membrane depolarization and enhanced electrical spike activity compared with controls. the slope of the membrane potenti ... | 1987 | 2957393 |
| the use of angiodynography to quantify blood flow in the canine aorta. | previous attempts to quantify blood flow by means of ultrasound have been hampered by inaccurate diameter measurements and failure to account for the parabolic nature of the cross-sectional velocity profile. angiodynography (adg) provides a b-mode image of vessel walls, and the outer flow envelope is constantly monitored to provide phasic diameter measurements throughout the cardiac cycle. frequency shifts are color-coded to provide a real-time visual display of varying velocity patterns across ... | 1987 | 2957515 |
| [sanitary education and its effect on the effectiveness of tuberculosis control]. | 2010 | 2957687 | |
| percutaneous transluminal angioplasty improves blood pressure and renal function in renovascular hypertension. | thirty-three patients with renal angiographic evidence of significant renal artery stenosis were referred for percutaneous transluminal angioplasty. the indications were poorly controlled hypertension (n = 13) or hypertension associated with deteriorating renal function (n = 20). their mean age was 56 (23-73) years (12 males, 21 females). causes of the renal artery stenosis were fibromuscular dysplasia (n = 8) and atheromatous changes (n = 25). four patients were excluded, three due to technical ... | 2010 | 2958895 |
| experimental evaluation of a new albumin-impregnated knitted dacron prosthesis. | the performance of a new albumin-impregnated, knitted vascular graft stored damp in saline was assessed by a comparative study in the canine aorta. knitted grafts interposed into the descending thoracic aorta for 4 weeks included: albumin-coated and stored damp in saline (damp albuminated) (n = 6), albumin-coated and freeze-dried (dry albuminated) (n = 5), collagen-coated (n = 4), and uncoated (n = 4). the results of macroscopic and microscopic evaluation were subjected to one-way analysis of va ... | 1987 | 2962524 |