Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| studies on the mechanism of intrinsic resistance to beta-lactam antibiotics in group d streptococci. | six penicillin-binding proteins (pbps) were detected in clinical isolates of each one of three group d streptococci: streptococcus bovis, s. faecalis and s. faecium. when examined in whole organisms, the pbps of s. faecium, the most penicillin-resistant species of group d streptococci, generally had lower affinities for the antibiotic than those of s. faecalis (intermediate penicillin resistance), which in turn were of lower affinity than those of s. bovis (penicillin-sensitive). on the other ha ... | 1983 | 6409985 |
| folate analogues. 22. synthesis and biological evaluation of two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system. | two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system have been synthesized and evaluated for their antifolate activities. these compounds, n-[(2-amino-4-hydroxy-7,8-dihydro-8-oxa-6-pteridinyl)benzoyl]-l-glutamic acid (3) and n-[[(2-amino-4-hydroxy-7,8-dihydro-8-oxa-6-pteridinyl) methyl]benzoyl]-l-glutamic acid (4), were synthesized by reacting the appropriately substituted alpha-halo ketones with 2,5-diamino-4,6-dihydroxypyrimidine (2). elaboration of p-carbomethox ... | 1983 | 6410065 |
| streptococci isolated from the bloodstream and gingival crevice of man. | one hundred and twenty six strains of streptococci isolated from the bloodstreams of 123 hospital in-patients--55 with endocarditis--and 255 strains isolated from the gingival crevices of 66 volunteers were characterised. species isolated were streptococcus mitior, s. sanguis, undifferentiated viridans streptococci, s. salivarius, s. milleri, s. mutans, s. bovis and s. faecalis. there was no significant difference between the distribution of species in blood and in the gingival crevice. s. mitio ... | 1983 | 6410069 |
| detection and activity of lactacin b, a bacteriocin produced by lactobacillus acidophilus. | a total of 52 strains of lactobacillus acidophilus were examined for production of bacteriocins. a majority (63%) demonstrated inhibitory activity against all members of a four-species grouping of lactobacillus leichmannii, lactobacillus bulgaricus, lactobacillus helveticus, and lactobacillus lactis. four l. acidophilus strains with this activity also inhibited streptococcus faecalis and lactobacillus fermentum, suggesting a second system of antagonism. under conditions eliminating the effects o ... | 1983 | 6410990 |
| identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin. | penicillin-binding protein (pbp) 5 of streptococcus faecium atcc 9790 has an unusually low affinity for penicillin (50% binding occurred at a penicillin level of 8 micrograms/ml after 60 min of incubation, and the protein only became labeled after 20 min of incubation with high concentrations of radioactive penicillin). pbps with similar properties are carried by strains of streptococcus durans, streptococcus faecalis, and streptococcus lactis but not by strains of groups a, b, c, and g streptoc ... | 1983 | 6411688 |
| transferable beta-lactamase. a new mechanism for in vitro penicillin resistance in streptococcus faecalis. | although enterococci are relatively resistant to penicillin, the mechanism of resistance is largely unknown and enzymatic inactivation does not play a role. in this study, an isolate of streptococcus faecalis was found to have beta lactamase activity resulting in complete inactivation of penicillin. with a high inoculum, this strain was resistant to greater than 1,000 micrograms/ml of penicillin. penicillin resistance and beta lactamase activity were transferred by conjugation at a high frequenc ... | 1983 | 6411768 |
| plasmid content of streptococcus faecalis strain 39-5 and identification of a pheromone (cpd1)-induced surface antigen. | streptococcus faecalis 39-5 is a haemolytic, bacteriocinogenic strain harbouring six plasmids. one of these plasmids, ppd1 (36.4 mdal) determines a bacteriocin and encodes a conjugative response to the sex pheromone cpd1 excreted by recipient (plasmid-free) strains. the pheromone response is characterized by the formation of mating aggregates of donors (responders) with recipients. aggregation required the presence of phosphate and divalent cations and was inhibited by agents or conditions that ... | 1983 | 6411857 |
| modification of streptococcus faecalis sex pheromones after acquisition of plasmid dna. | recipient strains of streptococcus faecalis excrete multiple, peptide sex pheromones that induce mating responses in donors harboring certain conjugative plasmids. acquisition of plasmid dna leads to a "shutting off" of pheromone excretion, and such cells become responsive to exogenous pheromone. data are presented showing that donors excrete low levels of a modified, inactive form of the pheromone. this substance, when mixed in excess with active pheromone, inhibits pheromone activity (probably ... | 1983 | 6412228 |
| folylpoly-gamma-glutamate synthetases: properties and regulation. | the substrate specificities of folylpolyglutamate synthetases from corynebacterium species, lactobacillus casei, streptococcus faecalis, and chinese hamster ovary (cho) cells are described. the purified corynebacterium enzyme catalyzes the addition of glutamate moieties to reduced pteroylmonoglutamates, and to 5,10-methylenetetrahydropteroyldi- and triglutamates. the purified protein also possesses a separate dihydrofolate synthetase activity. binding of pteroate substrates to dihydrofolate synt ... | 1983 | 6412521 |
| removal of bacteria from water by adhesion to cross-linked poly(vinylpyridinium halide). | cross-linked poly(vinylpyridinium halide) was found to have a novel and remarkable ability to remove bacteria from water. for example, when 10 g (wet weight) of cross-linked poly(n-benzyl-4-vinylpyridinium bromide) was contacted with 20 ml of suspensions of escherichia coli (9.7 x 10(4) to 9.7 x 10(7)/ml), salmonella typhimurium (8.0 x 10(6) to 1.1 x 10(7)/ml), streptococcus faecalis (5.0 x 10(7)/ml), staphylococcus aureus (8.1 x 10(7)/ml), and pseudomonas aeruginosa (3.2 x 10(5)/ml) under stirr ... | 1983 | 6412628 |
| the feasibility of screening preschool children for urinary tract infection using dipslides. | preschool children were screened for urinary tract infection (uti) using oxoid dipslides. a colony count of greater than 10(5) per ml was obtained from 64 out of 566 boys, and 58 out of 446 girls. a diagnosis of uti was established in 3 boys, all aged 6 months or less, and 5 girls. no child was found to have either vesico-ureteric reflux (vur) or renal scarring. false positive results were obtained in 15-17% of male and female infants and were attributable to the obligatory use of bag urine coll ... | 1983 | 6413443 |
| serum bactericidal activity and kinetics of azlocillin and moxalactam after single and combined administration. | ten healthy volunteers received 5 g azlocillin and 2 g moxalactam iv in single and combined administration. serum and urine concentrations were measured with bioassay and hplc (high pressure liquid chromatography), and serum bactericidal activity (sba) was determined at 1 h and 6 h against 6 different clinical isolates. the combined applications of both antibiotics resulted in minor differences in serum kinetics and urine recovery in comparison to single administration. sbas of both antibiotics ... | 1983 | 6413481 |
| in-vitro activity of azlocillin and other beta-lactam antibiotics against enterococci. | the susceptibility of enterococci to 16 beta-lactam antibiotics (5 penicillins, 11 cephalosporins) was evaluated by determining mics. all cephalosporins are ineffective against these bacteria. penicillin g should not be used to treat infections with enterococci. for less serious infections due to enterococci, ampicillin is certainly the drug of first choice. azlocillin, mezlocillin and piperacillin are the most effective drugs to prevent superinfections with enterococci in clinically and bacteri ... | 1983 | 6413483 |
| the killing effects of cefathiamidine or ampicillin alone and in combination with gentamicin against enterococci. | the in-vitro activity of cefathiamidine against streptococcus faecalis and str. faecium were studied in comparison with other beta-lactams. all the 56 strains of str. faecalis tested were inhibited by 2 mg/l of cefathiamidine. mics of ampicillin were twofold higher than those of cefathiamidine and mics of cephaloridine and cephazolin were 8-16-fold higher. no significant inoculum effect on mics of cefathiamidine could be seen. two isolates of str. faecium showed resistance to the four antibiotic ... | 1983 | 6413484 |
| taxonomic studies on some group d streptococci. | biochemical, menaquinone, fatty acid and dna analyses were conducted on a number of streptococci of serological group d. the results indicate that s. faecalis, s. faeclum, s. casseliflavus and taxa previously designated 's. avium', 's. durans' and "s. faecalis var. malodoratus' are distinct species. strains previously labelled 's. faecium var. mobilis' were shown to be identical with s. casseliflavus. the results also indicate that some group d streptococci recently isolated from chickens consti ... | 1983 | 6413643 |
| [fundamental and clinical studies of t-1982 (cefbuperazone) in the field of obstetrics and gynecology]. | t-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied. the following results were obtained. serum and internal genital tissue levels of t-1982 were measured following intravenous injection or intravenous drip infusion of 1 g. high serum levels of more than 10 micrograms/ml and tissue levels of more than 5 micrograms/g were maintained for 3 hours after intravenous administration. favourable transfer of t-1982 into the pelvic dead space exudate was observed. ... | 1983 | 6413727 |
| [fundamental and clinical studies on t-1982 (cefbuperazone) in the field of obstetrics and gynecology]. | t-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied in the field of obstetrics and gynecology. the following results were obtained. the concentrations of t-1982 in arterial and venous blood and genitalia following intravenous injection were measured. the results demonstrated favourable transfer of the drug into various internal genital organs. t-1982 was administered to 12 patients. the efficacy rate was 75.0%, that is to say, good in 9 cases. no side ef ... | 1983 | 6413728 |
| [clinical studies on effect of netilmicin in surgery]. | 1983 | 6413729 | |
| putrescine carbamoyltransferase (streptococcus faecalis). | 1983 | 6413820 | |
| isolation of a dna sequence related to several plasmids from bacillus thuringiensis after a mating involving the streptococcus faecalis plasmid pam beta 1. | the transmissible plasmid pam beta 1, which codes for resistance to erythromycin and lincomycin, was transferred from streptococcus faecalis to several strains of bacillus thuringiensis by a filter-mating process. introduction of pam beta 1 into the emr transconjugant strains of b. thuringiensis was confirmed by southern hybridisation using the 32p-labelled pam beta 1 as a probe. in the b. thuringiensis transconjugant strains, used as donors, the beta plasmid conserved its ability to be transfer ... | 1983 | 6413823 |
| antimicrobial activity of some thiol-containing heterocycles. | the minimum inhibitory concentration values for a group of synthesized heterocyclic systems were determined for gram-positive and gram-negative bacteria, yeast and fungi. the active compounds were screened further against a number of yeast and yeast-like organisms and gram-positive bacteria. the effect of two of these compounds on growth and mutagenicity was also tested. an attempt was made to correlate the structure of the compounds with their antimicrobial activity. | 1983 | 6413826 |
| chemical and immunochemical studies on lipopolysaccharides from pyocin 103-sensitive and -resistant neisseria gonorrhoeae. | the chemical and immunochemical properties of lipopolysaccharides (lps) isolated from pyocin 103-sensitive and -resistant neisseria gonorrheae were investigated. marked differences were found in immunochemical behavior of lps from pyocin-sensitive gonococcal strain jw31 and its isogenic pyocin-resistant variant jw31r. jw31 lps readily precipitated wheat-germ agglutinin, soybean lectin, and rabbit anti-streptococcus faecalis or horse anti-type 14 pneumococcal antibody. in contrast, jw31r lps prec ... | 1983 | 6414702 |
| dna interference with radioimmunoassay procedures. | a bacterial factor preventing precipitation of immune complexes was purified from a culture of streptococcus faecalis (ak strain) by gel filtration on sephadex g-100 and bio-gel a-150m columns. the factor was identified as dna on the basis of its ultraviolet absorption maximum at 260 nm, hydrolysis by deoxyribonuclease, mr exceeding 1.5 x 10(8), and positive reaction with diphenylamine. dna interferes with the immunoassay by preventing precipitation of immune complexes. only double-stranded dna ... | 1983 | 6414736 |
| in vitro susceptibilities of canine urinary bacteria to selected antimicrobial agents. | antimicrobial susceptibility tests were conducted on bacteria that were isolated from urine specimens collected by antepubic cystocentesis from dogs with urinary tract infections. antimicrobics to which greater than or equal to 90% of these urinary bacteria were susceptible in vitro included trimethoprim-sulfamethoxazole (tmp-smz), nitrofurantoin, cephalexin, nalidixic acid, and gentamicin for isolates of escherichia coli; ampicillin, tmp-smz, cephalexin, nalidixic acid, and gentamicin for isola ... | 1983 | 6415021 |
| medium-dependent zone size discrepancies associated with susceptibility testing of group d streptococci against various cephalosporins. | mueller-hinton (mh) agar media from various commercial sources, either supplemented or not supplemented with 5% sheep blood, were studied to determine their effect on disk diffusion susceptibility testing results obtained with 90 strains of group d streptococci and four cephalosporins. the cephalosporins investigated included cephalothin, cefamandole, moxalactam, and cefotaxime. results showed that a number of streptococcus faecalis and streptococcus faecium strains were susceptible to cephaloth ... | 1983 | 6415100 |
| cefamandole therapy in hand infections. | hand lacerations, especially when inadequately treated, may result in infections caused by aerobic or anaerobic bacteria. anaerobic infections most commonly result from human bite injuries in which there is contact between hand and mouth. the search continues for an ideal antibiotic to employ when anaerobic organisms are suspected. in this study cefamandole, a new cephalosporin antibiotic, was employed whenever anaerobic hand infections were suspected following trauma. in each patient quantitati ... | 1983 | 6415153 |
| evaluation of the antimicrobial potential of calcium hydroxide as an intracanal medicament. | 1983 | 6415201 | |
| therapeutic potential of rifampin in enterococcal infections. | rifampin is active against enterococci in vitro; virtually all clinical isolates are inhibited by concentrations of less than or equal to 16 micrograms/ml. however, rifampin is bacteriostatic, not bactericidal, and resistance emerges rapidly when the drug is employed alone against enterococci in vitro. the combination of rifampin with beta-lactam drugs, aminoglycosides, or vancomycin generally gives indifferent results. limited data from studies done in vivo are contradictory and do not document ... | 1983 | 6415781 |
| experimental urinary tract infection in rabbits by a group d streptococcus sp.: a study of serum immunoglobulin classes by enzyme-linked immunosorbent assay. | after induction of pyelonephritis and cystitis in rabbits by a group d streptococcus, the authors measured the specific serum antibody response in the three major immunoglobulin classes. the enzyme-linked immunosorbent assay was performed using group d streptococcal antigen extracted by phenol. before experimentation, all rabbits had low igm, igg and iga titres against group d streptococcal antigen. a marked increase in igm antibodies was detected during the first month of experimental pyeloneph ... | 1983 | 6416123 |
| the effects of subinhibitory concentrations of various antibiotics on phagocytosis of streptococcus faecalis. | this study reports the effects of subinhibitory concentrations of the antibiotics, clindamycin, gentamicin, moxalactam, and penicillin g, against 6 blood isolates of streptococcus faecalis to determine possible enhancement of phagocytosis. in addition, combinations of penicillin g plus streptomycin, penicillin g and gentamicin, and clindamycin plus gentamicin were studied to determine synergistic growth inhibition. results suggest no observable effect in phagocytosis from subinhibitory concentra ... | 1983 | 6417102 |
| division blocks in temperature-sensitive mutants of streptococcus faecium (s. faecalis atcc 9790). | two hundred nine temperature-sensitive growth or division (or both) mutants of streptococcus faecium atcc 9790 were isolated. these strains were examined for timing of the division block in the cell division cycle. about 42% of the isolates were blocked at terminal stages of cell division. a second large group appeared to be blocked at various stages of septation. only five of the temperature-sensitive isolates were blocked at a stage before the completion of chromosome replication. thirty tempe ... | 1983 | 6417107 |
| antibiotic prophylaxis against streptomycin-resistant and -susceptible streptococcus faecalis endocarditis in rabbits. | this report describes the capacities of ampicillin, vancomycin, streptomycin, gentamicin, and combinations thereof to prevent endocarditis in rabbits challenged with either streptomycin-resistant (three strains) or streptomycin-susceptible (one strain) streptococcus faecalis. vancomycin (15 mg/kg) alone was effective in preventing infection with three of four strains, including two which were streptomycin resistant. vancomycin (30 mg/kg) alone was effective against the other streptomycin-resista ... | 1983 | 6418063 |
| enumeration and speciation of group d streptococci from above and below a sewer outfall, their susceptibilities to six antibiotics and a comparison with clinical isolates. | isolates of group d streptococci from above and below a sewer outfall and a series of clinical isolates have been speciated to sub-species level. from below the sewer outfall, streptococcus faecalis var. faecalis predominates whereas above the outfall, s. faecium var. casseliflavus predominates. s. faecalis var. faecalis, s. faecalis var. liquefaciens and s. faecalis var. zymogenes were the predominant sub-species in the clinical isolates where s. faecium var. casseliflavus was virtually absent. ... | 1983 | 6418067 |
| synthesis of catalase by "streptococcus faecalis subsp. zymogenes". | "streptococcus faecalis subsp. zymogenes" was grown aerobically and anaerobically with glycerol as the source of carbon, and in the presence and absence of haematin. catalase activity was found only during aerobic growth in the presence of haematin. the rate of appearance of catalase activity was measured on (a) addition of haematin to haematin-less aerobic cultures, and (b) aeration of haematin-containing anaerobic cultures in the presence or absence of chloramphenicol. these experiments sugges ... | 1983 | 6418105 |
| comparison of the suitability of three common bacterial media for susceptibility testing of trimethoprim-sulfamethoxazole. | the in vitro inhibitory activity of trimethoprim-sulfamethoxazole is inversely related to the amount of thymine and thymidine in the test medium; manufacturers must adequately control their media to avoid spurious antimicrobial susceptibility results. no differences were observed when commercial mueller-hinton broth and agar were compared with a semisynthetic broth medium by the use of microdilution and disk diffusion techniques. | 1984 | 6418766 |
| application of s. faecalis and e. coli oral vaccines in humans and animals. | vaccines of non-pathogenic intestinal bacteria for oral administration have been used in the therapy of chronic and recurrent infections by the german medical association for microbiological therapy for over three decades. three different oral bacterial vaccines were used in particular: 1. a sterile autolysate of non-pathogenic s. faecalis and e. coli; 2. a viable non-pathogenic s. faecalis vaccine, and; 3. a viable non-pathogenic e. coli vaccine. clinical studies indicate the safety and efficac ... | 1983 | 6419280 |
| bactericidal activity of antimicrobial drugs in simulated urine specimens at various temperatures of incubation. | a total of 23 antimicrobial drugs were examined for bactericidal activity in midstream-urine against escherichia coli atcc 25922, pseudomonas aeruginosa atcc 27853, staphylococcus aureus atcc 25923, or streptococcus faecalis atcc 29212 at incubation temperatures of 35, 22, and 7 degrees c, respectively. the majority of chemotherapeutic agents significantly reduced bacterial inocula within 2 h at 35 degrees c. at room temperature, most drugs required 4 h for significant killing activity to ensue. ... | 1983 | 6419493 |
| ethmoiditis, conjunctivitis, and orbital cellulitis due to enterococcus infection. | 1984 | 6420105 | |
| inhibition of growth of staphylococcus aureus on sensitivity testing agar by streptococcus faecalis var zymogenes. | 1984 | 6420447 | |
| acquisition of k:1-like antigen during terminal sepsis. | this report describes a patient whose own and transfused k:-1 red cell populations became strongly k:1 during a terminal episode of sepsis due to a group d streptococcus organism, streptococcus faecium. subsequent in vitro studies using normal k:-1 red cells inoculated with that organism showed that it could render the red cells agglutinable by reagents containing igg anti-k1. in addition, disrupted s. faecium organisms rendered jkb-negative red cells agglutinable by those reagents. | 1984 | 6420953 |
| infected cardiac myxoma. | 1984 | 6421136 | |
| optimal therapy for enterococcal endocarditis. | enterococcal endocarditis accounts for an increasing proportion of cases of endocarditis in recent years. the combination of a penicillin and an aminoglycoside has become an accepted standard of treatment for this disease. however, the optimal choice of antibiotics, duration of therapy, and timing of surgical intervention remain controversial. this study reviews the presentation, clinical course, treatment, and outcome in 37 patients with 42 separate episodes of enterococcal endocarditis at four ... | 1984 | 6421157 |
| clarifying nomenclature. | 1983 | 6421203 | |
| echocardiographic features of bioprosthetic valve endocarditis. | abnormal echocardiographic findings in seven cases of bioprosthetic valve endocarditis were confirmed in six at operation. the echocardiograms showed three cases with thickening and increased echo intensity (group 1) and four (group 2) in which vegetations were seen initially without either of the two features in group 1. two patients in group 1 had vegetations, the causative organism being a streptococcus. staphylococcus epidermidis was the causative organism in three of the four cases in group ... | 1984 | 6421299 |
| peptide transport in bacteria: methods, mutants and energy coupling. | 1983 | 6421638 | |
| a microbiological evaluation of apalcillin. | the in vitro activity of apalcillin was tested against 350 clinical isolates of escherichia coli, enterobacter, klebsiella, proteus, pseudomonas aeruginosa and streptococcus faecalis. using a minimal inhibitory concentration of 16 mg/l as the breakpoint, only 19.7% of the strains were resistant to apalcillin. a regression analysis demonstrated that it is possible to test bacteria for sensitivity with a 20 micrograms apalcillin disc. the results on mueller-hinton agar are very similar to those on ... | 1983 | 6421745 |
| imipenem therapy of experimental staphylococcus aureus and streptococcus faecalis endocarditis. | imipenem was very active in vitro against 36 staphylococcus aureus isolates from cases of infective endocarditis; the mbc90 was 0.06 mg/l (four- to eight-fold more active than nafcillin). the in-vitro activity of imipenem against 22 streptococcus faecalis isolates from proven endocarditis cases was similar to that of penicillin g (mbc90 = 8 mg/l). imipenem was compared with nafcillin and with penicillin plus gentamicin in the therapy of experimental endocarditis induced in rabbits by staph. aure ... | 1983 | 6421794 |
| [stimulation of the natural self-purification of soil]. | connected with the elaboration of the sanitary norm of cadmium in soil were performed examinations to appoint the self-purification index. this index is the highest permissible concentration of a noxious chemical substance in soil not yet injuring irreversible the process of natural self-purification. as criterions of the self-purification were selected normal and potential respiration, quantity of bacteria, actinomyceta, fungi, proteolytic, nitrifying, and cellulolytic micro-organisms, inhibiti ... | 1983 | 6422669 |
| septic complications of percutaneous transhepatic biliary drainage. evaluation of a new closed drainage system. | in a consecutive study of 49 patients with obstructive jaundice who underwent preoperative percutaneous transhepatic drainage, the incidence of bacteria in bile at the time of insertion of the drainage catheter was 29 percent. patients drained with a conventional open drainage system showed an increase to 100 percent positive cultures after 20 days drainage. in this group, there was also a high incidence of episodes of bacteremia preoperatively and postoperatively and a high incidence of positiv ... | 1984 | 6422781 |
| minimal inhibitory concentrations of broad spectrum beta-lactam antibiotics for bacterial control strains. | the minimal inhibitory concentrations of 21 broad spectrum beta-lactam antibiotics for five bacterial control strains, as determined by a microtube method in cation-supplemented mueller-hinton broth, are reported. | 1983 | 6423341 |
| what do beta-lactamases mean for clinical efficacy? | beta-lactamases have proved to be extremely important in influencing therapy with penicillins and cephalosporins against gram-positive and gram-negative aerobic and anaerobic species. both plasmid mediated beta-lactamases which are primarily of a constitutive penicillinase type and the inducible chromosomal enzymes which are primarily cephalosporinases are important. the use of penicillins to treat haemophilus, neisseria gonorrhoeae, escherichia coli, klebsiella, salmonella, shigella and pseudom ... | 1983 | 6423546 |
| comparative activity of imipenem (n-formimidoyl thienamycin) on enterococci and its interactions with aminoglycosides. | activity of imipenem (n-formimidoyl thienamycin, ampicillin and vancomycin against 27 streptococcus faecalis and 5 str. faecium was determined. also evaluated were the interactions of imipenem, ampicillin and vancomycin with streptomycin or amikacin or sissomicin. imipenem showed the most inhibitory activity against str. faecalis with mic50 and mic90 values 0.5 and 2 mg/l respectively, str. faecium strains were less susceptible to imipenem with mic50/mic90 values of 2/16 mg/l. imipenem showed go ... | 1984 | 6423613 |
| experimental pyelonephritis. the effect of t-cell deficiency on the course of hematogenous enterococcal pyelonephritis in the mouse. | the course of experimental hematogenous pyelonephritis due to streptococcus faecalis was compared in athymic (nu/nu) mice and euthymic (nu/+) littermates. up to 7 weeks following infection, there were no significant differences in renal microbial populations. at 63 and 107-131 days there was significant escalation of infection in nu/nu mice, while the nu/+ mice were decreasing their infections. there was no increase in gross abscess formation in nu/nu mice, but in late stages significantly more ... | 1984 | 6424480 |
| rutin-induced beta-glucosidase activity in streptococcus faecium vgh-1 and streptococcus sp. strain frp-17 isolated from human feces: formation of the mutagen, quercetin, from rutin. | a fecal isolate, streptococcus sp. strain frp-17, and strain vgh-1 of streptococcus faecium were shown to contain beta-glucosidases which converted rutin (quercetin-3-o-beta-d-glucose-alpha-l-rhamnose) to quercetin and were active against o-nitrophenyl-beta-d-glucose. the activity against rutin could be measured by increased mutagenicity in the ames assay or visualized on thin-layer chromatography plates. in both organisms, the beta-glucosidase activities were inducible by the addition of rutin ... | 1984 | 6424566 |
| kinetic analysis of tetracycline accumulation by streptococcus faecalis. | tetracycline transport by streptococcus faecalis occurs by an energy-dependent, carrier-mediated process. the michaelis constant for transport was unchanged, but the maximal velocity was increased when an energy source, glucose, was present. accumulation levels, sometimes 25-fold greater than the external concentration, were controlled by the transport system. | 1984 | 6425265 |
| evaluation of the automicrobic system for detection of resistance of staphylococcus aureus to methicillin. | the automicrobic system (ams) (vitek system, inc., hazelwood, mo.) was tested for its ability to determine oxacillin and gentamicin susceptibility of 98 known oxacillin-susceptible and 103 known oxacillin-resistant staphylococcus aureus isolates. ams and reference oxacillin susceptibility results were in agreement for all 95 (100%) oxacillin-susceptible isolates. in contrast, only 23 (22.3%) of the 103 known oxacillin-resistant isolates were correctly reported. for the known oxacillin-resistant ... | 1984 | 6425359 |
| evaluation of a surfactant mixture c31g as a teat dip by a modified excised teat model. | a mixture of amphoteric surfactants with antimicrobial properties, c31g, was evaluated as a teat dip by a modified excised teat model. the model was modified to avoid misinterpretation of results from indigenous bacterial microflora on teats. in three experiments, bacterial numbers recovered from teats dipped in .75, 1.5, and 3.0% solutions of c31g were compared with bacteria recovered from undipped teats (negative controls) and teats dipped with 1.0% iodophor (an effective teat dip). mean log r ... | 1984 | 6425375 |
| what is the risk of beta-haemolytic streptococcal infection in obstetrics?: discussion paper. | 1984 | 6425498 | |
| [further studies on the effect of fluorides on the lactic acid production of bacteria]. | 1983 | 6425754 | |
| [a sensitive method for determining the proteolytic activity in culture filtrates]. | a new method for the quantitative determination of low proteinase activities in culture filtrates or other complex protein-containing substrates has been developed. the method is based on the inactivation of streptokinase which is monitored by following the reduction of fibrinolysis. in a time interval ranging from 1 to 500 min, the half-life of streptokinase activity is directly proportional to proteinase concentration. the enzymatic reactions are not interfered with by either other proteins or ... | 1983 | 6426194 |
| aminoglycoside accumulation by membrane vesicles of escherichia coli and streptococcus faecalis. | transport of nine aminoglycosides was studied in right side out as well as inside out membrane vesicles derived from aerobically or anaerobically grown e. coli and s. faecalis. right side out membrane vesicles prepared from aerobically grown e. coli and inside out membrane vesicles prepared from aerobically grown s. faecalis as well as inside out vesicles prepared from anaerobically grown e. coli took up all the aminoglycosides tested whereas right side out vesicles prepared from anaerobically g ... | 1983 | 6426196 |
| treatment of streptomycin-susceptible and streptomycin-resistant enterococcal endocarditis. | fifty-six patients with enterococcal endocarditis received 4 weeks of antimicrobial therapy with penicillin g and streptomycin (36 patients) or, if infections were streptomycin resistant, penicillin and gentamicin (20 patients). compared with patients who had symptoms for less than 3 months, patients with symptoms for more than 3 months had a higher relapse rate (0% versus 44%; p less than 0.001) and mortality (2.5% versus 25%; p less than 0.001). patients with mitral valve endocarditis had a si ... | 1984 | 6426359 |
| enigmatic enterococcal endocarditis. | 1984 | 6426360 | |
| distribution and effects of a defined six-member murine-derived microflora in gnotobiotic gerbils. | the gnotobiotic gerbil was selected as a model with which to study the effects of colonization with a defined microflora on organ morphology, histology, and selected blood biochemical parameters. gerbils were maintained germfree for 13 months but failed to reproduce, presumably because of the enlarged cecum. a colony of gnotobiotic gerbils that was associated with a bacterial flora consisting of lactobacillus brevis, streptococcus faecalis, staphylococcus epidermidis, bacteroides vulgatus, enter ... | 1984 | 6426388 |
| enterococcus: an unusual cause of septic arthritis. | 1984 | 6426482 | |
| tissue factor is a major stimulus for vegetation formation in enterococcal endocarditis in rabbits. | we examined the possible mechanisms of local initiation of coagulation in vegetation formation in enterococcal endocarditis by using a rabbit model. contact activation and tissue factor expression by freshly excised aortic valves were assessed using assays developed for use with cultured cells. bacteria alone lacked procoagulant activity and contact activation of plasma by excised valves did not occur. 4-d infected but not control valves expressed significant tissue factor activity (231 +/- 17 m ... | 1984 | 6427279 |
| scanning electron microscopy detects bacteria within infection stones. | the viability and location of bacteria within infection stones were investigated. many stones were infected with urea-splitting bacteria, such as proteus mirabilis and pseudomonas aeruginosa. large numbers of bacterial impressions and bodies were found in the interstices surrounded by crystals of apatite and struvite from the nuclei to the peripheral layers. the presence of bacterial colonies even in the nuclear portion of the stones suggests that bacteria participate in the initial stone format ... | 1984 | 6427487 |
| incubation temperature and faecal streptococci recovery from marine sediments. | a comparative work was carried out on two different incubation temperatures that may be used for faecal streptococci recovery. analyses were made on sediments samples collected in the bay of naples in a larger survey of environmental pollution detection. results showed a selective effect of 44 degrees c temperature on the isolation of the streptococcus faecalis, streptococcus faecium and streptococcus durans species that may be considered properly faecal streptococci. | 1984 | 6427553 |
| inhibition of neisseria gonorrhoeae growth due to hydrogen peroxide production by urogenital streptococci. | seven streptococci isolated from the normal urogenital flora were selected for the production of an inhibitory activity toward neisseria gonorrhoeae on solid medium. this activity was abolished when catalase was added to the medium in the case of streptococcus mitis isolates 22, 25, 74 and streptococcus sanguis ii isolate 70 suggesting the involvement of hydrogen peroxide. the inhibitory activities produced by the other isolates (streptococcus faecalis) were trypsin sensitive (isolates 12 and 14 ... | 1984 | 6427555 |
| [identification and sensitivity of streptococci to antibiotics]. | in the first part of this research, the author accentuates the quick and easy identification of the streptococcus by means of latex-test, testing at the same time the bacitracin. in the second part, the antibiotic sensitivity is tested on 354 strains of streptococci. | 1983 | 6427840 |
| comparative efficacies of mezlocillin and ampicillin alone or in combination with gentamicin in the treatment of streptococcus faecalis endocarditis in rabbits. | the in vitro and in vivo activities of mezlocillin and ampicillin, alone and in combination with gentamicin, against streptococcus faecalis were compared. in vitro, relative bactericidal and activities for 10 strains of s. faecalis were as follows: mezlocillin plus gentamicin greater than ampicillin plus gentamicin (p is not significant) greater than mezlocillin (p less than 0.01) greater than ampicillin (p less than 0.01) greater than gentamicin (p less than 0.01) greater than control (p less t ... | 1984 | 6428306 |
| susceptibilities of enterococci to twelve antibiotics. | the susceptibilities of 347 urine isolates of enterococci (streptococcus faecalis, 44%; s. faecalis subsp. zymogenes, 37%; s. faecalis subsp. liquefaciens, 19%) to ampicillin, azlocillin, mezlocillin, piperacillin, vancomycin, gentamicin, erythromycin, rosaramicin, rifampin, rifampin plus trimethoprim (1:4), trimethoprim-sulfamethoxazole (1:20), and chloramphenicol were determined by the agar dilution technique. there were no significant differences in susceptibility to individual agents among t ... | 1984 | 6428309 |
| control of wall band splitting in streptococcus faecalis. | computer reconstructions of 659 and 1325 whole mounted, shadowed cells, randomly chosen from cultures of streptococcus faecalis undergoing balanced growth and doubling in mass every 83 min and 30 min, respectively, were used to analyse the cell cycle. the size limits and duration of phases of the cell cycle were estimated by applying a method previously described by the authors, details of which are given here to allow others to use the method. deeply constricted cells whose primary septal radiu ... | 1984 | 6429274 |
| [specific immunity in patients with suppurative processes in the abdominal cavity]. | 1984 | 6429411 | |
| emergence of streptococcus faecalis isolates with high-level resistance to multiple aminocyclitol aminoglycosides. | isolates of streptococcus faecalis were occasionally found to be resistant to gentamicin concentrations of 500 micrograms/ml in a microdilution tray. additional tests were performed with 28 such isolates. they all demonstrated high-level resistance (minimum inhibitory concentration greater than 2000 micrograms/ml) to gentamicin, kanamycin, sisomicin, streptomycin, and tobramycin. this high-level aminoglycoside resistance was associated with total resistance to in vitro synergism when each aminog ... | 1984 | 6430629 |
| effect of media and blood on the antimicrobial activity of cephalosporins on serogroup d streptococci: a review. | the influence of culture medium on in vitro of selected cephalosporins on on group d streptococci was investigated by agar diffusion and broth dilution methods. the activity of cephalothin, cefamandole, and cefoperazone were not substantially influenced by the type of culture medium used, but cefuroxime, ceftizoxime, cefotaxime (ctx), cefmenoxime, and ceftriaxone varied markedly with both the commercial brand and the blood content of the broth used. the differences were more likely to occur in s ... | 1984 | 6430633 |
| [types of organisms isolated from blood cultures]. | 1984 | 6431029 | |
| [polymicrobial infection in terminal pneumonia in the aged]. | 1984 | 6431034 | |
| conjugal plasmids in group d streptococci. | 159 strains of group d streptococci isolated from clinical specimens were examinated for plasmids content. our objective was to study some characters carried by plasmids: drug-resistance, hemolysins and bacteriocin activity. 73,6% of the strains were antibiotic resistant and in 69% of these, the drug-resistance was transferable by conjugation. in mating of s. faecalis subsp. zymogenes strains we could also isolate three different types of transconjugants in hemolytic activity. the interpretation ... | 1984 | 6431229 |
| hematoporphyrin-sensitized photoinactivation of streptococcus faecalis. | 1984 | 6431458 | |
| cephalexin: interpretation of sensitivity disc testing in veterinary practice. | a regression study using 30 micrograms cephalexin sensitivity discs with bacterial strains isolated from veterinary sources is described. techniques suitable for use in veterinary investigation laboratories were used and critical zone sizes calculated from a linear regression analysis. zone sizes of less than or equal to 18 mm, 19 to 20 mm and greater than or equal to 21 mm were found to be suitable to categorise strains as resistant, intermediate or sensitive, respectively. experience in the us ... | 1984 | 6431568 |
| [comparative studies of antimicrobial agents against causative organisms isolated from urinary tract infections (1982). i. susceptibility distribution]. | in vitro activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections were investigated by dilution method using mic 2000 (dynatec) during july to october in 1982. the summarized results are as follows: pmpc and ccl have showed potent activities against e coli among the oral antimicrobial agents. pmpc and ccl at 3.13 micrograms/ml inhibited 90% of e. coli tested. ctm, ctx, czx, cmx and lmox at concentrations of 0.39 microgram/ml or less amon ... | 1984 | 6433064 |
| immune interferon production by th69, a lyophilized preparation of streptococcus faecalis, in murine spleen cell cultures. | in mouse spleen cell cultures, th69, a live streptococcus faecalis (atcc 31663) preparation, at a concentration of 20 micrograms/ml induced immune interferon (ifn gamma) with molecular weight ranging from 20,000 to 40,000 daltons together with a small amount of ifn alpha/beta. by using nonsensitized mouse spleen cells, the fact that both t-cells and macrophages are required for this ifn production was established. when these spleen cells were obtained from mice sensitized 12 days earlier with 4 ... | 1984 | 6433156 |
| emerging patterns of microbial resistance. | microbial resistance arises by mutation or by inheritance. the latter is plasmid-mediated and transferable and may erode multidrug resistance to beta-lactams, aminoglycosides, tetracyclines, macrolides, lincosamides, sulfonamides, and trimethoprim. resistance genes may transfer from one plasmid to another or from a plasmid to the chromosome or to a bacteriophage, thereby allowing rapid dissemination of resistance among bacteria. mutational or chromosomal resistance is not readily transferable be ... | 1984 | 6433290 |
| [microflora of dentobacterial plaque on approximal surfaces]. | 1983 | 6433683 | |
| evaluation of the kirby-bauer disc diffusion test as a screening test for high-level aminoglycoside resistance in enterococci. | the kirby-bauer disc diffusion test was evaluated as a test to detect high-level aminoglycoside (streptomycin, kanamycin, tobramycin, and gentamicin) resistance in isolates of enterococci. the authors found that high-level resistance could not be predicted accurately with the diffusion test. | 1984 | 6433696 |
| role of enterococcus in intraabdominal sepsis. | although enterococcus is well recognized as a pathogen in endocarditis, urinary tract infections, and biliary sepsis, its role in other forms of intraabdominal sepsis remains controversial. antibiotics that lack activity against enterococcus can often be employed successfully in intraabdominal infections, even when enterococci are present as part of the polymicrobial flora. furthermore, the enterococcus rarely emerges as a blood borne pathogen in such a setting. breakthrough enterococcal septice ... | 1984 | 6433734 |
| tyrosine decarboxylase. spectrophotometric assay and application in determining pyridoxal-5'-phosphate. | we have developed a highly sensitive and rapid spectrophotometric assay for tyrosine decarboxylase that can be applied to determining pyridoxal-5'-phosphate. in the assay, tyramine, a product of tyrosine decarboxylation, reacts with 2,4,6-trinitrobenzenesulfonic acid to give a product soluble in toluene whereas tyrosine does not. we determined the amount of tyramine produced enzymatically by reading the absorbance at 340 nm of a toluene extract of the reaction mixture. this method is capable of ... | 1983 | 6433791 |
| a turbidimetric and electron microscopic study of the effects of several parameters on the lysis of streptococcus faecalis by lysozyme. | the lytic effect of lysozyme on streptococcus faecalis atcc 9790 was studied by spectrophotometry and electron microscopy and it was found to be highly dependent on the ionic strength of the suspending media and on the ratio lysozyme to bacterial cell mass. when 7.2 x 10(8) bacteria/ml are exposed to 0.4 mg/ml of lysozyme in media with low ionic strength, the enzyme is bound in great amounts, as deduced from protein determinations and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sd ... | 1984 | 6434170 |
| interaction of anti-kojibiose antibody with the lipoteichoic acids from streptococcus faecalis and streptococcus faecium. | antisera prepared in rabbits by immunization with p-aminophenyl beta-kojibioside conjugated to bovine serum albumin (antikojibiose sera), readily agglutinated whole cells of streptococcus faecalis or streptococcus faecium, and showed specific reactions with the lipoteichoic acids (ltas) of these streptococci by passive hemagglutination, microscale enzyme-linked immunosorbent assay, and crossed immunoelectrophoresis. the interaction of the antikojibiose sera with the ltas was inhibited best by ko ... | 1984 | 6434429 |
| properties of atp-dependent protein kinase from streptococcus pyogenes that phosphorylates a seryl residue in hpr, a phosphocarrier protein of the phosphotransferase system. | transport of sugars across the cytoplasmic membranes of gram-positive bacteria appears to be regulated by the action of a metabolite-activated, atp-dependent protein kinase that phosphorylates a seryl residue in the phosphocarrier protein of the phosphotransferase system, hpr. we have developed a quantitative assay for measuring the activity of this enzyme from streptococcus pyogenes. the product of the in vitro protein kinase-catalyzed reaction was shown to be phosphoseryl-hpr by several indepe ... | 1984 | 6434522 |
| role of resistance to starvation in bacterial survival in sewage and lake water. | a study was conducted to determine the significance of starvation resistance to the ability of a species to survive in sewage and lake water. tests were conducted for periods of up to 14 days. rhizobium meliloti and one fluorescent and one nonfluorescent strain of pseudomonas were resistant to starvation because their population sizes did not fall appreciably in buffer and sterile lake water, and the first two maintained high numbers after being added to sterile sewage. cell densities of these b ... | 1984 | 6435525 |
| a randomized double-blind investigation of cefroxadine (cgp 9000) versus cephalexin in urinary tract infection. | a total of 64 out-patients with significant urinary tract infection were randomly allocated to treatment with cefroxadine 250 mg q.i.d. or cephalexin 500 mg q.i.d. for ten days. urine cultures were performed before allocation to the treatment groups and on days 0, 1, 3, 7 and 21. twenty patients discontinued treatment prematurely because of insignificant bacteriuria on day 0. both drug regimes--the cefroxadine dose was half that of cephalexin--showed good activity during treatment, and no statis ... | 1984 | 6436182 |
| identification of streptococci in a medical laboratory. | a total of 965 cultures of streptococci received at a reference unit for identification were examined with api-20 strep kits and also by established methods. the api method, although it needed to be supplemented with additional tests, largely overcame the difficulty that pyogenic streptococci are usually identified by their serological reactions and that biochemical tests are used for the identification of the other streptococci. representatives of at least 24 established or possible species wer ... | 1984 | 6436221 |
| comparison of latex agglutination and immunofluorescence for direct lancefield grouping of streptococci from blood cultures. | simulated positive blood cultures with 84 known stock strains of streptococci were used to comparatively evaluate the direct identification of these organisms by fluorescein-tagged antibody staining (immunofluorescence [if]) and latex agglutination (la). if was not evaluated for lancefield group d strains (a total of 81 strains tested) and had 89% sensitivity and 91% specificity. if was least sensitive for the identification of lancefield group f, in which three of seven strains showed no fluore ... | 1984 | 6436293 |
| influence of growth medium on the in vitro activities of second- and third-generation cephalosporins against streptococcus faecalis. | the influence of culture medium of the mics of eight cephalosporins for 45 strains of streptococcus faecalis was investigated. the mics of cephalothin, cefamandole, and cefoperazone were not substantially influenced by the type of culture medium used. in contrast, mics of cefuroxime, ceftizoxime, cefotaxime, cefmenoxime, and ceftriaxone varied markedly with both the commercial brand and the blood content of the broth used. the use of mueller-hinton broths (from oxoid ltd., gibco diagnostics, and ... | 1984 | 6436309 |
| quality control of susceptibility tests with 5-micrograms trimethoprim disks. | in 1981 and again in 1984, we performed multi-laboratory studies to develop quality control limits for susceptibility tests with 5-micrograms trimethoprim disks. zone size limits of 21 to 28 mm are recommended for tests with escherichia coli atcc 25922, and limits of 19 to 26 mm are recommended for tests with staphylococcus aureus atcc 25923. for screening mueller-hinton agar, tests with streptococcus faecalis atcc 33186 or atcc 29212 are recommended: zones should be fairly clear and greater tha ... | 1984 | 6436317 |
| killing capacity of human polymorphonuclear leukocytes in aerobic and anaerobic conditions. | the killing by human polymorphonuclear leukocytes of several species of bacteria, some of which were catalase positive, was examined in vitro in aerobic and anaerobic conditions. when all conditions other than the oxygen tension were identical, killing after 30 min was slightly greater in aerobic than in anaerobic conditions. however, after 60 and 120 min the difference between aerobic and anaerobic killing was smaller, and killing was nearly complete for all strains tested. these results confli ... | 1984 | 6436491 |
| [immunostimulation in an animal model using intestinal bacteria preparations]. | the treatment of mice with an injection preparation consisting of killed r-tribes of non-pathogenous e. coli caused an increase in microbicidic activities in the animal's blood and effects a significant protection against consecutive infections with salmonella typhimurium. the enhancement of the animal' resistance capacity appears to be non-specific, and connected with the activity of leucocytes. oral application of preparations of intestinal bacteria led to increased resistance against consecut ... | 1984 | 6436712 |
| [sensitivity of bacterial strains isolated from the urine in relation to type and frequency of use of antibacterial drugs (1972-1975, 1979-1981)]. | 1984 | 6436802 |