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visceral larva migrans in french adults: a new disease syndrome?visceral larva migrans is apparently an endemic disease among adults in southwest france. thirty-seven adults living in the midi-pyrenees region of france were confirmed as having visceral larva migrans based on an increased specific antibody titer to toxocara canis as detected by enzyme-linked immunosorbent assay (elisa) and by the western blot method. the disease was characterized clinically by weakness, pruritus, rash, difficulty breathing, abdominal pain, and pathologically by allergic manif ...19873578244
presumed toxocara canis with peripheral retinal granuloma and secondary macular hole.ocular manifestations of a presumed parasitic infection toxocaris canis were discovered in the eye of a 53-year-old male presenting for a routine examination. current serologic and skin tests were of little value in establishing the diagnosis, although the elisa immunosorbent agglutination serologic test was helpful but not definitive. the clinician therefore was forced to diagnose this disease based on the characteristic clinical findings.19873584809
control of toxocara canis in puppies: a comparison of screening techniques and evaluation of a dosing programme.conventional chemoprophylaxis of canine toxocariasis is based upon the treatment of young puppies. it is proposed that physiological considerations and the complexity of the host-parasite relationship in the case of toxocara canis demand that anthelmintic evaluation should properly be conducted in such animals rather than in adolescent or adult dogs. a screening model using the critical trial technique in early weaned pups gave variable results even with compounds known to be of high efficacy in ...19873586119
visceral larva migrans involving the myocardium: report of two cases and review of literature.two cases of asymptomatic visceral larva migrans (vlm) involving the myocardium, discovered during open heart surgery, are reported. only 7 cases of vlm myocarditis were found in recent english publications. all 7 cases involved children, with most of the patients acutely ill. our 2 asymptomatic cases, coupled with the high rate of positive serologic tests in the general population, stress the widespread nature of toxocara canis infection in human and the large number of subclinical, undetected ...19863588440
[pleural effusion and toxocara canis].toxocariasis is an infrequent disease which particularly affects children. toxocara canis is an uncommon parasite of man, who is not the normal host for the nematode. without doubt toxocara will be recognised more and more thanks to specific serological tests, in particular the elisa-esa test. the authors observed the association of a pleural reaction and a generalised hypereosinophilia (blood, pleural fluid and broncho-alveolar lavage). they noted a complete regression on mebendazole.19873589105
the effect of radiation on the viability and migratory ability of second-stage larvae of toxocara canis in mice.larval counts were made on mice 2 days after oral inoculation with x-ray (0-320 krad) or of gamma ray (0-6 mrad) irradiated eggs containing second-stage toxocara canis larvae. the majority of the larvae irradiated with 0-40 krad were recovered from the liver and lungs, while most of the larvae irradiated with 80 or 160 krad remained in the digestive tract, mainly in the stomach and the proximal half of the small intestine. only a small number of the 320 krad irradiated larvae was recovered from ...19873590613
[larva migrans visceralis--occurrence of ascarid eggs in sandboxes in the east german district city of cottbus].between 1982 and 1985 18 sand-pits were examined for toxocara canis eggs. eggs were found in 4 sand-pits. this implies a risk of larva migrans visceralis infection for children playing in these sand-pits. some measures for diminishing the contamination are recommended.19873619114
ocular toxocara canis infections: diagnosis by enzyme immunoassay.an enzyme-linked immunoassay (elisa) was used to establish the sero-prevalence of toxocara canis infection in several new zealand populations including those who, through environment or occupation, had close contact with dogs. the prevalence of positive elisa values found reflected the degree of dog contact, e.g. positive elisa's occurred in 2.8% of urban adults, 13.9% of dog breeders and 28.4% of hydatid control officers emphasizing that a history of dog contact needs to be considered when elis ...19873620188
homology and heterology between the secreted antigens of the parasitic larval stages of ascaris lumbricoides and ascaris suum.the materials released in vitro by the tissue-parasitic larval stages of the large roundworm of man, ascaris lumbricoides, were analysed by radio-iodination, immunoprecipitation, and sds-page. the antigens were found to be heterogeneous, ranging in molecular weight from 14 to 410 kd, and were found to alter radically during the parasites' migration to the lungs. the antigens secreted by the infective and lung-stage larvae of the pig homologue, ascaris suum, were compared with those of the human ...19873621674
asymptomatic toxocariasis in children. a prospective study and treatment trial.screening of 153 hispanic children attending a hospital-based primary care clinic revealed a 16 percent prevalence of toxocara canis infection. infections were found in other household occupants for half of these children. follow-up of 20 children (for periods of up to 7 years) with asymptomatic t. canis infection failed to demonstrate any clinical sequelae. however, longer periods would be necessary to entirely discount the possibility of latent ocular disease. treatment with thiabendazole did ...19873621769
[comparative studies on slab-page of proteins of ascaris lumbricoides, ascaris suum and toxocara canis]. 19873623535
[differential diagnosis between retinoblastoma and ocular toxocariasis].we studied the sensitivity for toxocara canis (elisa technique) in 5 cases of retinoblastoma confirmed by anatomopathological examination. some presented with a positive reaction in serum and/or in aqueous. now that surgical technique are available that permit to functionally save eyes affected by toxocariasis, we felt that a safe and reliable differential diagnosis between toxocariasis and retinoblastoma is of major importance. a positive elisa test even in the aqueous fluid does'nt seem reliab ...19873624795
toxocara canis infection and hyperactivity.an observational study using video recordings and computer assisted data analysis showed that infection with toxocara canis larvae had a marked effect on five readily and reliably differentiable categories of murine behaviour. the infection was also associated with an increase in the number of shorter bouts of each behavior. these results indicate that infection with t. canis renders mice hyperactive, and would appear to justify a complete reappraisal of the role of this neurotropic parasite as ...19863632100
the impact of single versus repeated exposure of mice to toxocara canis.infection with t. canis can alter dramatically the brain and behavior of the host. previous results suggest that if the mammalian host is exposed either simultaneously to lead, or has a history of prior exposure to that toxic substance, the magnitude of the behavioral reaction to t. canis may be modified or even reduced. the present data suggest that the magnitude of both the behavioral and tissue/immune reactions may be less if the organism has multiple, instead of a single exposure, to t. cani ...19873659146
parasitic infections in yakima indians.two hundred and five yakima indians (age range: one to 66 years) were examined for parasitic infections, and various environmental exposures to infection. a questionnaire was completed by each participant and an anal swab, blood specimens and a single faecal sample were obtained. eight of 181 swabs (4.4%) contained eggs of enterobius vermicularis. of 89 faecal specimens submitted, 12 (13.5%) and 1 (1.1%) respectively contained giardia lamblia and cryptosporidium. sera were screened for antibodie ...19873662670
the consequences of parasitic infection for the behavior of the mammalian host.as many as one billion people may be infected with animal parasites. the behavioral consequences of such infection, or of illness in general, is poorly understood. this issue is discussed using as an example infection of mice with toxocara canis, the common roundworm of dogs. current literature suggests that two-thirds of all dogs have been infected with this parasite, and 7% of all humans have antibodies to t. canis. t. canis completes its life cycle in dogs, but when it infects aberrant mammal ...19873665867
comparative study of assays detecting circulating immune complexes and specific antibodies in patients infected with toxocara canis.a sandwich elisa method using previously described e/s antigen-specific monoclonal antibodies has been developed to detect circulating immune complexes in patients infected with toxocara canis. this technique could be used for the study of the dynamics of the parasite-host relationship, as we believe the detection of immune complexes and/or soluble antigen to be an improvement over detection of antibodies only. in this parasitosis, antibodies may be present in residual levels for prolonged perio ...19873668209
superoxide dismutase activity in nematodes.the activities of the enzymes superoxide dismutase (e.c.:1.15.1.1) and catalase (e.c.:1.11.1.6) were studied in purified extracts of four nematodes: ascaris suum, toxascaris leonina, toxocara canis and t. cati adult males and females. no catalase activity was found in any of the extracts. the results reveal that the sod activities of the four parasites presented species differences and also sexual differences within each species. polyacrylamide gel electrophoresis pattern analysis confirmed that ...19873668213
[ocular form of toxocara canis infection in children]. 19873669545
parasites of stray dogs in the rabat region, morocco.eighteen parasites were identified from 57 stray dogs from the urban and rural areas of rabat. the prevalence of the species of parasites was: ctenocephalides (c. canis, c. felis) 94.7%, rhipicephalus sanguineus 68.5%, linguatula serrata, babesia canis, isospora canis each 3.5%, toxocara canis 7%, dirofilaria immitis, taenia hydatigena, t. pisiformis each 12.3%, dipetalonema dracunculoides 10.5%, ancylostoma caninum 17.5% echinococcus granulosus 22.8%, toxascaris leonina 33.3%, dipylidium caninu ...19873675044
toxocara canis: interaction of human blood eosinophils with the infective larvae.this study was carried out to investigate the nature of the immunological responses which took place in a child who had recently recovered from toxocariasis. she had developed a marked eosinophilia and had high titers of toxocara antibodies. experiments were performed to examine whether toxocara canis infective larvae could be killed in the presence of her serum and human eosinophils. eosinophils with human complement, or this patient's serum, adhered to the surface of the larvae within 10 min. ...19863709753
enzyme immunoassay (elisa) for the detection of specific igg antibodies to toxocara canis es antigens.this paper reports the development of an enzyme-immunosorbent assay for the detection in human serum of specific igg against excretory/secretory antigens of second stage toxocara canis larvae. similar tests have been already used in several countries for clinical and epidemiological purposes on human toxocariasis and currently represent the only specific means for the serological diagnosis of this parasitic disease. specificity and sensitivity have been proved and original data on the epidemiolo ...19863718679
prevalence of soil contamination by toxocara canis eggs in qalubiya governorate. 19863722882
chemotactic reactivity of eosinophils obtained from bone marrow and peritoneal cavity of cyclophosphamide-treated, toxocara canis-infected mice.chemotactic reactivity of eosinophils obtained from the bone marrow (bm-eo) of cyclophosphamide-treated, toxocara canis-infected mice was compared to that of eosinophils obtained from the peritoneal cavity (pec-eo). bm-eo responded well to alanyl-tetrapeptide, a synthetic eosinophil chemotactic factor of anaphylaxis (ecf-a), whereas pec-eo did not. both bm-eo and pec-eo showed almost equally high chemotactic reactivity to parasite-derived ecf, ecf lymphokine and complement-derived ecf. chemotact ...19863733233
nonspecific allergic granulomatosis in the lungs of mice infected with large but not small inocula of the canine ascarid, toxocara canis.infection of cba/j mice with 250 ova of toxocara canis results in development of splenic lymphocytes hyperergic to nonspecific stimuli. these studies were performed to see if the granulomatous response to a nonspecific stimulus was exaggerated. using eosinophil counts and mbsa ear thickening it was demonstrated that concurrent infection with the parasite and immunization with methylated bovine serum albumin (mbsa) elicit no immunologic cross reactions. eosinophil counts were proportional to the ...19863742887
neuroretinitis in presumed visceral larva migrans.neuroretinitis is a rate manifestation of toxocariasis that can occur as a late sequelae to the active disseminated phase of the disease visceral larval migrans (vlm). this case report describes a 14-year-old boy who developed vlm and concurrent neuroretinitis. during the acute illness, the patient's serum elisa titer to toxocara canis rose to greater than 256 and a lymph node biopsy revealed necrotizing lymphadenitis with eosinophilia. the constitutional symptoms of vlm may be mild and easily o ...19863749627
[in vitro interaction between immunocompetent cells and l2 larvae of toxocara canis: immunologic aspects]. 19863752818
[the l2 larva of toxocara canis as an immunomodulating agent]. 19863752819
experimental toxocariasis and hyperactivity in mice.an observational study using videorecordings and computer-assisted data analysis was undertaken in order to investigate the behaviour of mice infected with larvae of toxocara canis. the findings indicated that the infection had a marked effect on five readily and reliably differentiable categories of murine behaviour. a marked increase in the number of shorter bouts of each of the five behaviours was also associated with the infection. these results support previous findings and further suggest ...19863754367
toxocara canis infestation. clinical and epidemiological associations with seropositivity in kindergarten children.we studied a cohort of 333 children in kindergarten to determine the prevalence of seropositivity to toxocara canis, and to detect and measure chronic health effects that might be attributable to past infection. we found that 23.1% of the children had serologic evidence of infection (antibody titer greater than or equal to 1:32), assayed by means of an enzyme-linked immunosorbent assay. black children were more frequently infested than white children, as were children of parents who did not grad ...19863763150
[epidemiological aspects of toxocariasis in switzerland].in the regions of basel, jura and zürich (switzerland) 765 blood donors completed a questionnaire with respect to symptoms, animal contacts and occupation, and their sera were tested for antibodies to tissue helminths in elisa. 5.1%, 3.3% and 6.5% exhibited antibodies solely to the respective antigens of toxocara canis, fasciola hepatica, and echinococcus granulosus. combined seroreactions were mainly observed between f. hepatica and e. granulosus antigens. reactivity to t. canis antigen was ass ...19863764384
the relationship between toxocara elisa absorbance values and toxocara elisa titres: a comparative study.enzyme-linked immunosorbent assays (elisas) may be made by a variety of techniques at one or several serum dilutions which is very confusing for clinicians. this study compares the elisa results from two centres on sera from 12 patients investigated for ocular toxocariasis by two common elisa methods--the absorbance and titration techniques. with one exception, elisa results by the two methods correlated well. for reasons outlined, the absorbance elisa method is likely to remain the preferred me ...19863768173
toxocara canis infection of children in a caribbean community. 19863768596
purification and properties of mitochondrial malate dehydrogenase of toxocara canis muscle.mitochondrial malate dehydrogenase was purified from muscle extracts of toxocara canis by means of sephadex g-100 gel filtration, deae-sephadex ion-exchange chromatography and 5'amp-sepharose 4b affinity chromatography. the purified enzyme showed an optimum ph for the reduction of oxaloacetate of 7.3 in tris-hcl buffer and of ph 7.5-7.8 in phosphate buffer. the m-mdh showed values of 3.2 kcal/mol and 10.5 kcal/mol for the energy of activation, calculated from the arrhenius equation. the mitochon ...19863769454
[quantitative comparison of amino acids in adult proteins of ascaris lumbricoides, ascaris suum and toxocara canis]. 19863770717
[larva migrans visceralis--occurrence of toxocara canis in dogs in the east german district of cottbus].larvae of the nematode genus toxocara are the main causative agents of the l.m.v. syndrom. 5,002 dogs from the cottbus district aged between 2 and 36 months were examined. 994 animals (19.9%) were found to be infected with toxocara canis. dogs from a rural area have a higher infection rate (25.6%) than dogs from an urban area (15.2%). the relatively high infection rate of dogs, high egg-production and the tenacity of the development stages are factors dangerous to human health.19863777527
toxocariasis: a serological survey of blood donors in the australian capital territory together with observations on the risks of infection.the sera from 660 healthy blood donors from canberra were tested for antibodies to toxocara canis by the elisa test. the results were compared with those from patients with suspected or confirmed visceral larva migrans or ocular toxocariasis. over 7% of canberra sera showed elevated levels of antibody reacting with t. canis antigen. sera from patients resident in australia with other helminth parasites did not cross-react with t. canis antigen in our tests. however, studies of sera collected in ...19863787682
enzyme-linked immunosorbent assay (elisa) for the detection of antibodies to angiostrongylus cantonensis.the enzyme-linked immunosorbent assay (elisa) was employed for the sero-diagnosis of angiostrongylus cantonensis infections in rats and man. metabolic and 'purified' antigens of adult or juvenile a. cantonensis were evaluated by elisa and compared against toxocara canis antigen for sensitivity and specificity. sera and cerebrospinal fluid (csf) from both rats and man gave higher elisa values against antigens of a. cantonensis than those obtained from negative control samples. the results showed ...19863798533
ultrastructural studies of alterations induced by microwaves in toxocara canis eggs: prophylactic interest.the ultrastructure of toxocara canis eggs is described before and after exposure to microwaves. the morphology of normal eggs is compared to that of eggs from other helminths. following treatment, the complete disorganization of the surface structure of the shell and the loss of much turgidity of the egg are observed. the destruction of the internal structure is most marked in the center of the egg and is associated with the disappearance of some layers of the shell. in addition, there is substa ...19863799007
[clinical, hematologic and serologic findings in puppies after prenatal infection with toxocara canis werner 1782 (anisakidae)]. 19863799098
the prevalence of parasitic helminths in stray dogs in the baghdad area, iraq.the prevalence of parasitic helminths in 20 stray dogs from the area of baghdad was recorded. taenia spp. were found in 12 dogs, dipylidium caninum in ten dogs, toxocara canis in eight dogs, ancylostoma caninum in seven dogs and echinococcus granulosus in five dogs. spirocerca lupi and dirofilaria immitis were found in three dogs, mesocestoides lineatus in two dogs and strongyloides stercoralis in one dog.19863800471
an immunochemical investigation of the allergens from ascaris suum perienteric fluid. cross-reactivity, molecular weight distribution and correlation with phosphorylcholine-containing components.an extract of ascaris suum perienteric fluid was fractionated on sephadex g-200 and the resulting high molecular weight (approx. 600,000 daltons) and low molecular weight (approx. 16,000 daltons) fractions examined for allergenicity using human sera. radioallergosorbent (rast) and rast-inhibition assays showed that the high molecular weight fraction was 15- to 40-fold more potent than the low molecular weight fraction. crossed radio-immunoelectrophoretic analysis showed that the high molecular w ...19873804458
intestinal parasites in pet store puppies in atlanta.we examined 143 pups from 14 atlanta area pet stores for intestinal parasites and reviewed deworming practices and information given to customers. seventy-four (52 per cent) of the pups had at least one parasite including giardia sp. (34 per cent), toxocara canis (12 per cent), and isospora sp. (9 per cent). eighty-eight per cent received some form of anthelminthic treatment while at the store. only six (43 per cent) of the stores routinely informed clients of the need to continue deworming proc ...19873812843
circulating excretory-secretory antigen levels and specific antibody responses in mice infected with toxocara canis.circulatory excretory-secretory antigen levels and igm and igg responses to larval antigens were monitored in the serum of 20 balb/c mice that had been given approximately 500 infective eggs of toxocara canis by stomach tube. other groups of mice received different doses of infective eggs, ranging from 5 to 1,250 eggs. excretory-secretory antigens were collected from culture fluid in which mechanically hatched larvae of t. canis were maintained. an indirect enzyme-linked immunosorbent assay was ...19873812886
anthelmintic effect of levamisole hydrochloride or ivermectin on tissue toxocariasis of mice.paranatal transmission of toxocara canis infection could be prevented in pups if an effective drug were administered to pregnant bitches. this drug also could eliminate the larvae in dogs that have been experimentally infected repeatedly to produce protective immunity. for these reasons, we assayed the effect of 2 doses of levamisole hydrochloride or ivermectin on t canis larvae. mice (5 groups) were infected with 1,000 infective t canis larvae and then treated with 2 different dosages of levami ...19873826867
intestinal helminths of domestic dogs in the hessian neckar valley, federal republic of germany.in a small town and its adjacent villages of the hessian neckar valley, federal republic of germany, 155 of the officially registered domestic dogs were examined for intestinal helminths. twenty percent of the animals proved to be infected. the highest prevalence of 5.8% could be attributed to infections with toxocara canis. these values are well below the average rates for dogs in the larger german cities.19853833828
canine and human gastrointestinal helminthiasis of the kainji lake area, nigeria.an investigation into gastrointestinal helminthiasis in human and dog population of the kainji lake area revealed a high prevalence of helminthiasis which may be due to lack of adequate health and veterinary facilities; crowdiness and squalid environment. the prevalent parasites in humans were ancylostoma sp, 40.33%; ascaris lumbricoides, 44.07% and strongyloides stercoralis 4.05%, while in dogs ancylostoma sp, 36.95%, dipylidium caninum, 28.26%, echinococcus granulosus, 8.69% and s. stercoralis ...19853833832
[what is your diagnosis? geophagia complicated by toxocara canis infection]. 19853835540
[inflammatory pseudoglioma caused by toxocara canis (anatomo-clinical study of a case)]. 19853841849
toxocaral infection in hydatid control officers: diagnosis by enzyme immunoassay.an enzyme-linked immunosorbent assay for toxocara canis larva excretory/secretory antigen has been set up in christchurch. employing this test, elevated specific antibody levels for toxocara larvae were found in 3.3% (3/90) of urban adult blood donors and 4.4% (4/90) of secondary school students. in comparison, elevated levels were present in 25.6% (23/90) of new zealand hydatid control officers. it can be concluded from the present study that the higher risk of toxocariasis experienced by hydat ...19853863049
studies on the prevalence of gastro-intestinal helminths of dogs in calabar, nigeria.the results of investigational study to determine the prevalence of gastro-intestinal helminths of dogs in calabar, nigeria with particular emphasis on the effects of sex and age of the animals on the occurrence of these endoparasites are presented. of a total of 254 dogs sampled using saturated brime solution floatation method and formalin-ether sedimentation method, 223 (86.97%) were infected. a breakdown of the number of parasitized dogs shows that 180 (70.86%) were positive for ancylostoma c ...19853869127
comparative studies on the infestation of three different breeds of dogs by gastro-intestinal helminths.the findings of an investigation mounted to evaluate and compare the prevalence of parasitic gastro-intestinal helminth ova in three different breeds of dogs in calabar, nigeria are presented. results of the investigation indicate that in alsatians, 25% infestation with strongyloides stercoralis, 25% toxocara canis, 65% ancylostoma caninum were found, in crossbreed between alsatian and mongrel, 15.56% infestation with strongyloides stercoralis, 10.93% toxascaris leonina, 25% toxocara canis, 68.7 ...19853869810
[parasites present in foxes (vulpes vulpes) of the province of forli].in the period march 1983 - march 1984 a parasitological survey was carried out on 103 foxes killed in the forli province (italy). the parasites identified were: toxocara canis (45.6%); uncinaria stenocephala (14.6%); mesocestoides lineatus (9.7%); dipylidium caninum (2.9%); taenia crassiceps (2.9%); trichuris vulpis (2.9%). out of all the cestodes found in 7 animals the authors identified only genus taenia since their preservation conditions were not optimal. other 13 subjects contained many ces ...19853870647
[visceral larva migrans caused by toxocara canis]. 19853878545
specific antibody responses in dogs experimentally infected with echinococcus granulosus.six dogs reared helminth-free were divided into 2 groups. four dogs were infected per os with 200,000 protoscoleces each of echinococcus granulosus and 2 were kept as uninfected controls. all the dogs were kept together until 32 days after infection, when 1 infected dog was killed, its intestine removed and the contents examined to confirm that the infection with e. granulosus had been successful. the remaining 3 infected dogs were transferred to high security housing and their feces inspected d ...19863953947
[migration and distribution of toxocara canis werner 1782 (anisakidae) larvae in the definitive host (beagle) following primary infection and reinfection]. 19853976310
induction of non-ige anaphylactic antibodies in dogs.dogs immunized with o-dncp-bsa or eggs of toxocara canis developed anaphylactic antibodies other than ige. the antibodies were heat-resistant at 56 degrees c for 2 hours, not reduced by 2-mercaptoethanol and pca and p-k reactivity was only observed at 3-4 h sensitized sites of recipient skin. high titres of antigen-specific iggd were determined by means of an elisa technique.19853978874
prenatal and lactational transmission of toxocara canis and ancylostoma caninum: experimental infection of the bitch before pregnancy. 19853980144
toxocara canis in humans. 19853980978
in vitro translation of mrna from toxocara canis larvae.300 micrograms of total rna was extracted from 1 ml of packed toxocara canis larvae by centrifugation through a 5.7 m cesium chloride cushion. 60 micrograms of polyadenylated messenger rna was separated from 300 micrograms of total rna in an oligothymidylic acid-cellulose gel column. the in vitro translation of the mrna, isolated from t. canis larvae, was carried out using the rabbit reticulocyte cell-free translation system. incorporation of [35s]methionine into trichloroacetic acid precipitabl ...19853990707
immune responses of cba/j mice to graded infections with toxocara canis.the immunological responsiveness of cba/j mice infected with various numbers of the canine ascarid, toxocara canis, was characterized after a single infection to ascertain the smallest infection capable of perturbing the immune system of the host. mice receiving the lowest inoculations (5 eggs per mouse or 0.25 larvae per g of body weight) had detectable alterations in the number of circulating peripheral blood eosinophils and spleen weight-to-body weight ratios. mice infected with 25 eggs each ...19853997242
induction of a marked eosinophilia by cyclophosphamide in toxocara canis infected sjl mice.cyclophosphamide (cy) is known to produce a marked eosinophilia in mice after antigen challenge. in this study, we studied the effect of cy on eosinophilia in helminthic infection. peripheral blood eosinophils were counted in sjl mice following a large dose of cy injection, infection with toxocara canis, and both cy injection and t. canis infection simultaneously. following the injection with cy (150 mg/kg), the eosinophil counts fell sharply, then rose abruptly to six times the normal level fol ...19854011300
do toxocara canis larval antigens used in enzyme-linked immunosorbent assay for visceral larva migrans cross-react with ab isohemagglutinins and give false positive results?a variety of helminth parasites have a and b blood group antigens on their surface. these antigens may cross-react with elevated concentrations of a and b isohemagglutinins in some patients and give false-positive results in the serologic diagnosis of visceral larva migrans caused by t. canis. to clarify this point, serum from patients with visceral larva migrans and elevated t. canis antibody titers as determined by elisa were absorbed with ab blood cells and retested by elisa without a demonst ...19854013469
anthelmintic efficacy of febantel combined with praziquantel in dogs.ninety-four dogs were randomly assigned to 1 of 6 groups (5 treated and 1 untreated control) for evaluation of anthelmintic efficacy. three anthelmintic formulations were studied: a febantel paste, a praziquantel paste, and a combination paste containing both active ingredients. treated dogs were dosed once daily for 3 days. the minimal effective dosages in combination were established as 10 mg of febantel and 1 mg of praziquantel/kg of body weight. at those dosages for the combination, 99.5% to ...19854030460
biosynthetic labelling of the excretory and secretory antigens of toxocara canis larvae.toxocara canis larvae were cultured in vitro in medium containing [35s-]methionine for six days. the medium and the larval tissues were analysed for biosynthetically labelled polypeptides by sodium dodecyl sulphate polyacrylamide gel electrophoresis and autoradiography. immunoprecipitates with positive and negative human antiserum were similarly analysed, using staphylococcus aureus to absorb immunocomplexes. the larvae secrete biosynthetically labelled polypeptides into the medium, with three m ...19854031454
regulation of toxocariasis in mice selectively reared for high and low immune responses to nematospiroides dubius.test mice have been selectively reared for high (h) or low (l) immune responses to nematospiroides dubius. after secondary infection with n. dubius, the l mice voided ten times as many eggs in their faeces as the h mice, and at necropsy, 71% versus 20% of the inoculum of n. dubius were recovered as adult worms from the l and h mice respectively. furthermore, n. dubius were more fecund in the l than in h mice. high or low immune responsiveness was not restricted to n. dubius infection in these mi ...19854031456
toxocara canis larvae in the brain of a british child.the clinical and autopsy findings of a two and a half year-old infant with toxocara sp. infection of the brain and granulomatous lesions in the liver are reported. the cause of death was non-accidental injury. the relationship between toxocara infection and behavioural disorders is discussed.19854035735
the radioallergosorbent test (rast) for the serological diagnosis of human anisakiasis.the serum of patients with parasitologically confirmed and one patient with a clinically presumptive case of anisakiasis were tested by the radioallergosorbent test (rast) and counter-electrophoresis (cep) for ige and igg antibodies, respectively, using antigens prepared from larval (l3) stage anisakis simplex and larval (l2) stage toxocara canis. all sera were rast-positive to the a. simplex antigen and rast-negative to the t. canis antigen. all sera were cep-negative to both antigens. the pres ...19854039859
seroprevalence of zoonotic toxocariasis in the united states: 1971-1973.demographic characteristics associated with human toxocara canis infection in children aged one to 11 years were investigated using data from the health and nutrition examination survey of 1971 to 1973. an enzyme-linked immunosorbent assay with larval stage antigen was used to measure the concentration of antibodies to t. canis in 1,409 available sera. from 4.6 to 7.3% of the children in different geographic regions of the united states have been infected, with serologic prevalence approaching 3 ...19854050776
the progression of behavioral and pathological effects of the parasite toxocara canis in the mouse.toxocara canis, the parasitic roundworm of the dog may infect aberrant hosts including mice and humans. the present study examined the behavioral and pathological changes at each of three postintubation periods (period 1: 8-10 days, 2: 49-51 days, and 3: 84-86 days postintubation, respectively) in independent groups of mice intubated with 1000 eggs of t. canis. eight-ten days after intubation toxocara infected animals typically showed depressed levels of activity relative to saline-intubated con ...19854059398
ocular toxocariasis studied by ct scanning.ocular toxocara canis infection causing larval granulomatosis and leading to chronic endophthalmitis and retinal detachment is a well-defined cause of unilateral leukokoria in children. the computed tomographic (ct) scan revealed a diffuse, nonenhancing, well-defined hyperdense lesion occupying most of the globe. the ct findings do not definitively differentiate the diffuse endophthalmitis of larval granulomatosis from retinoblastoma or other pseudogliomas.19854059556
prenatal and lactational transmission of toxocara canis and ancylostoma caninum: experimental infection of the bitch at midpregnancy and at parturition. 19854066142
[effect of fenbendazole on resting somatic larvae of toxocara canis werner 1782 (anisakidae) in the pregnant bitch]. 19854072489
behavioral effects of early lead exposure and subsequent toxocariasis in mice.mice were maintained under standard conditions, or treated with lead from birth, until they were approximately 40 d of age. at that time the lead solution was replaced with tap water and all animals were gastrointestinally intubated with either the parasite toxocara canis or normal saline. at 2-5 wk following intubation the behavioral effects of t. canis in combination with the prior history of lead ingestion were compared to those produced by administration of either t. canis or lead alone or a ...19854078936
anthelmintic efficacy of flubendazole paste against nematodes and cestodes in dogs and cats.small dogs and cats, naturally infected with nematodes and cestodes, were used in a critical test under laboratory conditions to determine the palatability and efficacy of flubendazole as a past formulation. subsequently, a control test in dogs was conducted under field conditions. a 4.4% past formulation was given at a dosage of 22 mg/kg of body weight once a day for 2 or 3 consecutive days. in a critical test in dogs, the efficacy against toxocara canis was 97.4% after a 2-day administration a ...19854083589
transfer of infection-induced immune protection to toxocara canis in a mouse model.groups of mice were vaccinated twice with soluble extracts of embryonated eggs, females or males of toxocara canis, or horse serum, and infected with 2,000 homologous embryonated eggs. recovery of larvae on the fifth day by digestion of mesenteric lymph nodes, liver, lung, brain, and carcass revealed a slight but nonsignificant protection elicited by the parasite materials. other groups were immunized by homologous infections. a single, 200-day-old infection increased importantly the number of l ...19854090262
the effect of toxocara canis on the spontaneous running activity of mice. 19854096567
[immunological diagnosis of larva migrans visceralis infection caused by toxocara canis (author's transl)]. 19744134613
antigenic analysis of a metazoan parasite, toxocara canis. ii. purification and analysis of two antigenic components. 19674165232
ascaris suum and toxocara canis: radioautographic detection of dna in feulgen-negative muscle nuclei. 19704192595
immunoglobulin class of antibodies in monkeys infected with toxocara canis. 19744219215
amino acid composition of ascaris lumbricoides, a. suum and toxocara canis. 19684234371
ascaris suum infection in calves. 3. pathology.gross changes in the lungs of ascaris suum- infected calves consisted of atelectasis and hemorrhagic foci, edema and emphysema, frequently with bullae. prominent microscopic lung lesions were edema and emphysema of the interlobular septa with large numbers of eosinophils within and around lymphatics, peribronchiolar lymphoid nodules and parasitic granulomas. many of the microscopic features were consistent with those found in atypical interstitial pneumonia. changes in the alveoli were atelectas ...19704248444
[immunofluorescence diagnosis of experimental infection of mice with toxocara canis. antigen testing for the diagnosis of the disease in humans]. 19714258399
parasites of dogs from indian settlements in northwestern canada: a survey with public health implications.a total of 959 faecal samples were obtained from dogs in 12 native communities in northern saskatchewan, central and northern alberta and the northwest territories. all samples were examined using a flotation technique. samples from an area of endemic human amoebic infections were also examined by a formol-ether sedimentation method. eighteen necropsies were performed. entamoeba histolytica cysts were recovered from dog faeces at loon lake, saskatchewan. toxocara canis had low incidence in saska ...19734265550
electron microscopy of the lung in experimental toxocara canis infection. 19744368663
ascaris suum infection in calves. i. clinical signs.clinical signs consistent with those of atypical interstitial pneumonia (aip) were induced in calves sensitized with infective ascaris suum eggs at seven to 20 weeks of age and challenged at three-week intervals one or more times. these signs usually appeared on the sixth or seventh day postinfection and reached maximum severity between the tenth and 13th days following infection. prominent signs were: dyspnea, often with expiratory grunt, coughing, mouth breathing and emphysema as well as incre ...19704394225
toxocara canis infestation with encephalitis. 19744434267
[erg- and eog-examination results in cases of toxocara canis retinochorioiditis (author's transl)]. 19744449170
preparation of sterile toxocara canis larvae. 19744474384
[intraocular infection by toxocara canis]. 19724638564
the distribution of toxocara canis larvae in the central nervous system of rodents. 19724653047
toxocara canis: some characteristics of larval precipitating antibodies in rat serum. 19724661481
a study of the effect of diethylcarbamazine and thiabendazole on experimental toxocara canis infection in mice. 19724668710
experimental studies on visceral larva migrans of toxocara canis in laboratory animals. 19724669287
[the visceral larva migrans syndrome due to toxocara canis]. 19724677981
thiabendazole for control of toxocara canis in the dog. 19734691488
the nature of resistance of immune puppies to superinfection with toxocara canis: evidence that immunity affects second-but not fourth-stage larvae. 19734722664
helminthiasis in dogs in uganda. i. recovery of strongyloides stercoralis by lindsey's method. ii. recover of dirofilaria repens. iii. aberrant habitation by ancylostomum caninum, spirocerca lupi and toxocara canis. 19734802495
the geography of ocular toxocara canis. 19744821365
Displaying items 301 - 400 of 1954