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enzymatic production of caffeic acid by koji from plant resources containing caffeoylquinic acid derivatives.the effect of a koji (aspergillus awamori mut.) extract on the caffeoylquinic acid derivatives purified from sweetpotato (ipomoea batatas l.) leaves was examined to develop the mass production of caffeic acid. a koji extract hydrolyzed the caffeoylquinic acid derivatives, chlorogenic acid, 3,4-di-o-caffeoylquinic acid, 3,5-di-o-caffeoylquinic acid, 4,5-di-o-caffeoylquinic acid and 3,4,5-tri-o-caffeoylquinic acid, to caffeic acid. furthermore, the koji extract also converted the major polyphenoli ...200516195601
[double-blind randomized trial of the effect of bidro on hay fever in children].the natural product royal jelly (trade name bidro) is widely used for the treatment and prevention of allergic symptoms. several case reports suggest marked clinical benefits. our aim was to assess whether treatment with royal jelly modifies the development of allergic hay fever symptoms in children with pollen allergy.200516219189
[ineffective change of antimalaria prophylaxis to artemisia vulgaris in a group travelling to west africa].sixteen travellers to west africa used four kinds of antimalaria chemoprophylaxis. suspected malaria in three persons and vaginal candidiasis in one caused all seven doxycycline users to change their medication. one of these was persuaded to use artemisia vulgaris extract. in the course of the three-month journey, there were seven suspected cases of malaria, only two of which could be confirmed by antibody and antigen detection or expert microscopy; both were in travellers who had used a. vulgar ...200516251093
comparative anti-hyperglycemic potentials of medicinal plants.validation of the ethnobotanical use of the leaves of artemisia vulgaris linn. (compositae), eucalyptus tereticornis sm. (myrtaceae), solanum nigrum linn. (solanaceae), and vitex negundo linn. (verbenaceae); stems of nopalea cochinellifera (linn.) salm-dyck (cactaceae); roots of imperata cylindrica beauv. (gramineae); dried bark of syzygium cumini (linn.) skeels (myrtaceae) as anti-diabetic agents using the oral glucose tolerance test showed that only the bark of syzygium cumini and the leaves o ...200616253452
the spectrum of allergens in ragweed and mugwort pollen.ragweed and mugwort are important allergenic weeds belonging to the asteraceae or compositae plant family. pollen of mugwort is one of the main causes of allergic reactions in late summer and autumn in europe and affects about 10-14% of the patients suffering from pollinosis. ragweed pollen represents the major source of allergenic protein in the united states, with a prevalence of about 50% in atopic individuals. in europe, ragweed allergy is now rapidly increasing particularly in certain areas ...200516254437
cancer incidence in 13811 patients skin tested for allergy.several studies have shown a negative correlation between cancer and atopy-related diseases. there are also a few reports of a positive relationship. we wanted to further evaluate these relationships in a prospective study.200516261950
[occupational allergy to mugwort].mugwort (artemisia vulgaris) has traditionally been used as a spice, vegetable and as a herbal medicine. the main representatives of the artemisia family besides artemisia vulgaris include artemisia absinthum and artemisia dracunculus (estragon). mugwort pollen allergens are important in triggering late summer and fall pollinosis; in addition cross reactivity occurs between artemisia vulgaris pollen allergens and celery, carrottes and certain spices belonging to the family of umbelliferae.200316285482
[relationship between pollen allergy and oral allergy syndrome].we recently evaluated the relationship between pollen allergy and oral and pharyngeal hypersensitivity to fruits and vegetables (oral allergy syndrome) over 8 years (1995 approximately 2002) in sapporo. 1. of 843 patients with birch pollen (bp) allergy (cap score 2 or more), 378 patients (37%) had episodes of oral allergy syndrome (oas), and the rate in bp allergy was higher than in other allergies. 2. in patients with bp allergy, the most frequent foods causing oas were apple, peach and cherry, ...200516285612
occupational asthma due to carrot in a cook.few previous reports of carrot-induced asthma have been confirmed by objective tests. hypersensitivity to carrot is frequently associated with allergy to apiaceae spices and sensitization to birch and mugwort pollens.200516287550
antioxidant activity of various teas against free radicals and ldl oxidation.tea is a widely consumed beverage throughout the world. we assessed the antioxidant activity of six teas, including the aqueous extracts of green tea and oolong tea (camellia sinensis), tochu (eucommia ulmoides), gymnema sylvestre, japanese mugwort (artemisia princeps), and barley (hordeum vulgare), against 1,1-diphenyl-2-picrylhydrazyl (dpph) radicals and ldl oxidation, and examined the association of ldl oxidizability with the plasma catechin levels in 10 healthy volunteers with a single dose ...200516296404
[the point of view of moxibustion in the book, a general survey of moxibustion].to study on academic point of view of the book, a general survey of moribustion.200516309163
allergoid-specific t-cell reaction as a measure of the immunological response to specific immunotherapy (sit) with a th1-adjuvanted allergy vaccine.specific immunotherapy (sit) is believed to modulate cd4+ t-helper cells. in order to improve safety, sit vaccines are often formulated with allergoids (chemically modified allergens). interaction between t-cells and allergoids is necessary to influence cellular cytokine expression. there have been few reports on identification the early cellular effects of sit.200516433203
the course of eczema in children aged 5-7 years and its relation to atopy: differences between boys and girls.the role of atopy in the pathophysiology of eczema is still under debate. the concept and analyses of the nonatopic and atopic subtypes of eczema have gained increasing interest in recent studies. the course of these subtypes and differences between boys and girls have not been investigated so far.200616445783
nasal provocative test in patients allergic to pollen.nasal provocative test (npt) can be defined as a method for recreating upper respiratory tract response to natural allergens or irritants. it can be used in solving nasal patophisiology problems: establishing whether and how the patient's nose is sensitive to antigens or irritants; quantitative evaluation of sensitivity; establishing factors influencing sensitivity. this method is employed to confirm clinical diagnosis in cases where difficulties arise in interpretation of diagnostic tests. the ...200516457469
the antioxidative power ap--a new quantitative time dependent (2d) parameter for the determination of the antioxidant capacity and reactivity of different plants.in the last decade, naturally occurring antioxidants continue to play an important role in the food-supplement industry. the content of antioxidants in a plant depends on the species, temperature, humidity, period of growth, harvest month, part of the plant used and many other variables. herein, we present a new method able to determine the all over antioxidative power (ap) of plant extracts or lyophilised plant parts based on the reducing activity against a stable test radical. the method is pe ...200616490383
side-effects of allergen-specific immunotherapy: a prospective multi-centre study.the safety of allergen-specific immunotherapy (sit) is a parameter of great interest in the overall assessment of the treatment. a clinical database was developed in order to obtain early warnings of changes in the frequency and severity of side-effects and sufficient data for the evaluation of possible risk factors.200616499635
pollen-food syndromes associated with weed pollinosis: an update from the molecular point of view.pollinosis patients often display adverse reactions upon the ingestion of plant-derived foods as a result of immunoglobulin e (ige) cross-reactive structures shared by pollen and food allergen sources. the symptoms of such pollen-food syndromes (pfs) or class 2 food allergies range from local oral allergy syndrome to severe systemic anaphylaxis. two clinical syndromes, the celery-mugwort-spice syndrome and the mugwort-mustard-allergy syndrome have been described in association with weed pollinos ...200616512809
skin test reactivity among danish children measured 15 years apart.knowledge of secular trends in the prevalence of allergy among children stems in large part from questionnaire surveys, whereas repeated cross-sectional studies using objective markers of atopic sensitization are sparse.200616517432
[effect of the physiological-biochemical characteristics variability on a radiosensitiveness of the atriplex patula l. and artemisia vulgaris l. ecoforms].on the example of the physiological and the cytology-biochemical characteristics variability of an atriplex patula l. and artemisia vulgaris l. sprouts which parental plants were generated in various environmental conditions (south yakutia, the central yakutia, middle ural), was shown, that radiostability depends not only on set protective antioxidant, on the dna-reparation systems and on the vulnerability degree of a functioning genome, but also on the phenotypic diversifications of a populatio ...200616579547
plant bioassays for an in situ monitoring of air near an industrial area and a municipal solid waste: zilina (slovakia).the process of a bioindication of genotoxic effects of complex mixtures on the environment using higher plants is very appropriate and effective. we present the results of an in situ indication of the genotoxic effects of polluted environment near zilina city. for a more complex monitoring we used: the tradescantia micronucleus (trad-mcn) assay, the tradescantia microspore test and an evaluation of the abortivity of the pollen grains of native plant species. we found significant differences in t ...200616617421
the performance of a component-based allergen-microarray in clinical practice.currently, the diagnosis of ige-mediated allergy is based on allergen-specific history and diagnostic procedures using natural allergen extracts for in vivo and in vitro tests.200616629796
artemisia and ambrosia hypersensitivity: co-sensitization or co-recognition?ragweed and mugwort have nearly identical flowering periods. clinical and serological studies showed that ragweed and mugwort sensitization are often associated and this poses relevant clinical problems in patients for whom specific immunotherapy is warranted.200616650052
rhinitis symptoms and ige sensitization as risk factors for development of later allergic rhinitis in adults.rhinitis symptoms and ige-sensitization often mismatch. asymptomatic sensitization is an established risk factor for later rhinitis, whereas it is not clear whether rhinitis is a risk factor for later development of ige-sensitization.200616677240
cabbage lipid transfer protein bra o 3 is a major allergen responsible for cross-reactivity between plant foods and pollens.food ige-mediated allergy to members of the brassicaceae family has been increasingly reported.200616751008
sensitization to different pollens and allergic disease in 4-year-old swedish children.although the relationship between sensitization to different inhalant allergens in adolescents and adults has been intensively studied, information concerning sensitization in children is scarce in particular to pollens.200616776672
chemical composition of the essential oils of serbian wild-growing artemisia absinthium and artemisia vulgaris.the chemical composition of the aerial and root essential oils, hydrodistilled from artemisia absinthium l. and artemisia vulgaris l. (wild-growing populations from serbia), were studied by gas chromatography, gas chromatography-mass spectrometry, and 13c nuclear magnetic resonance. during the storage of plant material under controlled conditions, a significant decrease of essential oil yields (isolated directly after drying and after 1 year of storage) and significant differences in their chemi ...200616787028
integration of flowering dates in phenology and pollen counts in aerobiology: analysis of their spatial and temporal coherence in germany (1992-1999).we studied the possibility of integrating flowering dates in phenology and pollen counts in aerobiology in germany. data were analyzed for three pollen types (betula, poaceae, artemisia) at 51 stations with pollen traps, and corresponding phenological flowering dates for 400 adjacent stations (< 25 km) for the years 1992-1993 and 1997-1999. the spatial and temporal coherence of these data sets was investigated by comparing start and peak of the pollen season with local minima and means of plant ...200616832654
cross-reactive and species-specific immunoglobulin e epitopes of plant profilins: an experimental and structure-based analysis.profilins are cross-reactive plant allergens responsible for multiple pollen sensitization and pollen-associated food allergy. while it is assumed that profilins from different species are immunologically equivalent, some studies suggest partial or even lacking ige cross-reactivity between certain profilins.200616839408
the major allergen of olive pollen ole e 1 is a diagnostic marker for sensitization to oleaceae.trees of the family oleaceae are important allergen sources, with a strongly varying geographic distribution. for example, olive pollen is an important allergen source in mediterranean countries, whereas ash pollen dominates in northern and central europe and north america. the aim of this study was to compare the profiles of olive and ash pollen allergens and to study the degree of cross-reactivity using populations of allergic patients selectively exposed to olive or ash pollen.200616864978
[local differences of oral allergy syndrome with pollinosis--a comparison between hanshinkan and higashiharima in south hyogo].a number of cases of oral allergy syndrome (oas) to fruits with birch pollinosis have been described. the antigen of alnus sieboldiana (alder) trees which are massively planted on rokko mountain appeared to be highly similar to birch pollen.200616883108
[mugwort-- medicinal plant and drug, spice and allergen]. 200616886513
mugwort, a. vulgaris. 200616937739
potassium excretion in healthy japanese women was increased by a dietary intervention utilizing home-parcel delivery of okinawan vegetables.potassium, which is abundant in vegetables, is inversely related to blood pressure. although the situation has changed somewhat in recent years, the okinawan diet has generally included a large amount of vegetables, and until recently okinawans had the lowest rates of mortality due to stroke and coronary heart disease in japan. based on the hypothesis that these low mortality rates are partly attributable to increased potassium intake resulting from the high vegetable consumption, this study exa ...200616940700
differential allergen sensitization patterns in chestnut allergy with or without associated latex-fruit syndrome.chestnut allergy has been almost exclusively considered in the context of the latex-fruit syndrome. chestnut allergens not linked to latex hypersensitivity have not been studied.200616950291
metals and arsenic in soils and corresponding vegetation at central elbe river floodplains (germany).floodplain soils at the elbe river are frequently polluted with metals and arsenic. high contents of these pollutants were detected down to subsoil layers. nh4no3-extractable (phytoavailable) cd, ni, and zn were elevated in horizons with high acidity. among five common floodplain plant species, artemisia vulgaris showed highest concentrations of cd, cu, and hg, alopecurus pratensis of as and phalaris arundinacea of ni, pb, and zn. relationships were weak between metal concentrations in plants an ...200716996182
the role of protein glycosylation in allergy.the asparagine-linked carbohydrate moieties of plant and insect glycoproteins are the most abundant environmental immune determinants. they are the structural basis of what is known as cross-reactive carbohydrate determinants (ccds). despite some structural variation, the two main motifs are the xylose and the core-3-linked fucose, which form the essential part of two independent epitopes. plants contain both epitopes, insect glycoproteins only fucose. these epitopes and other fucosylated determ ...200717033195
[relationships between oral allergy syndrome and sensitization to pollen antigen, especially to mugwort].in order to know the relationships between mugwort pollinosis and oral allergy syndrome (oas), an etiological study was performed at muroran city, where mugwort is the most frequent cause of pollinosis.200617072112
bee pollen sensitivity in airborne pollen allergic individuals.physicians who practice alternative medicine often prescribe bee pollen as a food supplement and a treatment for various ailments.200617165283
variations in mugwort (artemisia spp.) airborne pollen concentrations at three sites in central croatia, in period from 2002 to 2003.in spite of the low atmospheric pollen levels, artemisia sensitisation and allergy has been reported widely. the aim of the study was to determine the length of pollen season, intradiurnal, daily and monthly pollen variation, and the effect of some meteorological parameters on atmospheric pollen concentrations in central croatia. seven-day hirst volumetric pollen and spore traps were used for pollen sampling. the artemisia pollen season lasted from the end of july until the end of september with ...200617243566
anaphylaxis to honey in pollinosis to mugwort: a case report.a case of anaphylaxis to honey in a 19 year old female sensitized to compositae pollen is described. the patient suffered from summer rhinoconjunctivitis since seven years; in january 2006, ten minutes after eating bread and honey she developed angioedema of the lips and tongue, runny nose, cough, dyspnoea, and collapse, requiring hospitalization and treatment with high dose corticosteroids and anti-histamines. after two weeks, skin prick tests (spt) with a standard panel of inhalant allergens a ...200617274522
specific immunotherapy in atopic dermatitis--four-year treatment in different age and airborne allergy type subgroups.atopic dermatitis (ad) is a common inflammatory disease involving the skin and frequently other organs and systems such as respiratory system. the recently recognized atopic nature of the skin inflammation in ad has raised a growing interest in the treatment with allergen-specific immunotherapy (sit). in this study, the efficacy of sit was evaluated in a group of 37 ad patients aged 5-44 years: 14 allergic to house dust mites (hdm), 17 to grass pollen allergens, and 6 allergic to grass and mugwo ...200617328144
cloning, expression and characterization of mugwort pollen allergen art v 2, a pathogenesis-related protein from family group 1.mugwort (artemisia vulgaris) belongs to the compositae family, and is one of the main causes of allergy in late summer and autumn. the aim of the study was to characterize the allergen art v 2 from mugwort pollen. skin prick tests, performed in 19 patients allergic to mugwort and 10 control patients, showed an art v 2 sensitization prevalence of 58%, whereas none false-positives were detected among control patients. art v 2 was purified by standard chromatography and binding to concanavalin a co ...200717521730
exotic food allergy: anaphylactic reaction to lychee.there are very few reports on allergic reactions to lychee fruit in the literature. we describe the case of a 26-year-old man who developed pruritus, generalized urticaria, and severe angioedema of his lips and tongue with dyspnea within 15 minutes after lychee fruit intake. although we found no lychee-specific immunoglobulin e antibodies, a basophil activation test (bat) and a cellular antigen stimulation test (cast) to lychee were both positive, as was a prick-to-prick test with fresh lychee f ...200717583110
ethnoveterinary medicines used to treat endoparasites and stomach problems in pigs and pets in british columbia, canada.this paper documents the medicinal plants used to treat endoparasites and stomach problems in dogs, cats and pigs in british columbia, canada. ethnoveterinary data was collected over a 6-month period in 2003. the majority of the information on pets came from 2 naturopaths, 10 herbalists, 5 dog trainers, breeders and pet shop owners, 9 holistic veterinarians and 6 of 27 organic farmers. two pig farmers joined the study in the final stages. the following plants were used as anthelmintics: artemisi ...200717628343
[what is the role of allergic sensitization in graves' disease?].recent data supported the presence of t helper 2 dominance in the immune processes of graves' disease and allergic diseases. a common role of regulatory t cells in the antigen- (or allergen-) specific immune responses was also demonstrated.200717631469
quantification of art v 1 and act c 1 being major allergens of mugwort pollen and kiwi fruit extracts in mass-units by ion-exchange hplc-uv method.a simple ion-exchange hplc-uv method was developed for determination of major allergens from mugwort pollen and kiwi fruit extracts in mass-units. the separation of art v 1 and act c 1 from other components in the extracts was achieved in one step. the extinction coefficients used in the study were theoretically determined and compared to the extinction coefficients determined by gravimetry. we also reported a close correlation of the major allergen contents with the overall allergenic potency o ...200717652037
hla dr-dq haplotypes and the tnfa-308 polymorphism: associations with asthma and allergy.the hla (human leukocyte antigen) class ii genes dqb1 and drb1 and the tumor necrosis factor alpha gene (tnfa) within the hla complex (chromosome 6p21) have been associated with asthma and allergy. due to the strong linkage disequilibrium characterizing this complex and the multiple asthma/allergy expressions, we aimed to determine which of these genes were primarily involved in specific asthma/allergy traits.200717686102
sympatric host races of the european corn borer: adaptation to host plants and hybrid performance.the european corn borer (ecb), ostrinia nubilalis, is a major pest of maize crops. in europe, two sympatric host races are found: one feeds on maize (zea mays) and the other mainly on mugwort (artemisia vulgaris). the two host races are genetically differentiated, seldom crossing in the laboratory or in the field, and females preferentially lay eggs on their native host species. we conducted two independent experiments, in field and greenhouse conditions, to determine whether the two host races ...200717714289
genetic structure and gene flow in french populations of two ostrinia taxa: host races or sibling species?most models of ecological speciation concern phytophagous insects in which speciation is thought to be driven by host shifts and subsequent adaptations of populations. despite the ever-increasing number of studies, the current evolutionary status of most models remains incompletely resolved, as estimates of gene flow between taxa remain extremely rare. we studied the population genetics of two taxa of the ostrinia genus--one feeding mainly on maize and the other on mugwort and hop--occurring in ...200717822415
prevalence of ige-binding to art v 1, art v 4 and amb a 1 in mugwort-allergic patients.mugwort (artemisia vulgaris) represents an important source of weed pollen allergens. the objectives of the present study were (i) to analyze the ige binding profiles in a group of mugwort-allergic patients, (ii) to identify individual marker allergens crucial for the diagnosis of mugwort allergy and (iii) to identify potential crossreactive allergens present in ragweed (ambrosia artemisiifolia) pollen extract.200817823540
strategy for allergenicity assessment of 'natural novel foods': clinical and molecular investigation of exotic vegetables (water spinach, hyacinth bean and ethiopian eggplant).foods not commonly consumed in the european union must be proven safe before being brought to market, including an assessment of allergenicity. we present a three-stepwise strategy for allergenicity assessment of natural novel foods using three novel vegetables, namely, water spinach, hyacinth bean, ethiopian eggplant.200717919138
[oral allergy syndrome due to plant-derived foods: a clinical review of 63 patients over a period of 6 years].the clinical features of many patients with oral allergy syndrome (oas) due to plant-derived foods have rarely been reported in japan.200717982289
sensitization to tomato peel and pulp extracts in the mediterranean coast of spain: prevalence and co-sensitization with aeroallergens.tomatoes (lycopersicon esculentum) are consumed world-wide. the prevalence of sensitization to tomatoes remains unknown.200818005185
effectiveness of mugwort lotion for the treatment of post-burn hypertrophic scars. 200818033748
molecular and functional analysis of the antigen receptor of art v 1-specific helper t lymphocytes.ninety-five percent of patients with mugwort allergy are sensitized to art v 1, the sole major allergen in mugwort (artemisia vulgaris) pollen. sixty-nine percent of patients recognizing the single immunodominant t-cell epitope art v 1(25-36) have an hla-drb1*01 phenotype.200818037161
aniseed-induced nocturnal tongue angioedema.aniseed is a spice native to the eastern mediterranean region. cases of simultaneous hypersensitivity to celery, mugwort pollen, and spices of the umbelliferae family have been described as the celery-mugwort-spices syndrome. we report a case of aniseed-induced tongue angioedema. skin prick tests to foods proved positive only to aniseed. serum-specific immunoglobulin (ig) e determination by enzyme allergosorbent test was 0.4 ku/l to aniseed extract and 0.6 ku/l to tare and cumin seeds. the molec ...200718088024
anaphylaxis after oseltamivir (tamiflu) therapy in a patient with sensitization to star anise and celery-carrot-mugwort-spice syndrome. 200818186817
immunogold electron microscopic localization of the 2 ef-hand calcium-binding pollen allergen phl p 7 and its homologues in pollens of grasses, weeds and trees.the 2 ef-hand calcium-binding allergen from timothy grass pollen, phl p 7, contains the majority of relevant ige epitopes among calcium-binding allergens occurring in pollen species of different plants.200818204277
cross-allergenicity of pollens from the compositae family: artemisia vulgaris, dendranthema grandiflorum, and taraxacum officinale.chrysanthemum, dandelion, and mugwort belong to the compositae (asteraceae) family. their cross-allergenicity has not yet been completely evaluated.200718219834
sensitization to turnip rape and oilseed rape in children with atopic dermatitis: a case-control study.turnip rape and oilseed rape 2s albumins are new allergens in children with atopic dermatitis suspected for food allergy. we recently found that 11% (206/1887) of these children had a positive skin prick test to seeds of oilseed rape (brassica napus) and/or turnip rape (brassica rapa). in the present case-control study we examined how the children with atopic dermatitis sensitized to turnip rape and oilseed rape had been breast-fed and whether they had some common sensitization pattern to certai ...200818221477
differences in oviposition behaviour of two sympatric sibling species of the genus ostrinia.changes in host preferences are thought to be a major source of genetic divergence between phytophagous insect taxa. in western europe, two sympatric taxa, o. nubilalis (the european corn borer) and o. scapulalis, feed mainly on maize and hop or mugwort, respectively. these two species may have diverged without geographic isolation after a host shift of ancestral populations onto maize or another cultivated species (e.g. sorghum). a previous study using inbred laboratory strains revealed that th ...200818257953
[threshold pollen count necessary to evoke allergic symptoms].the purpose of this study was to analyze the relation between clinical picture of allergic disease and the level of pollen count the patients are exposed to.200718260258
sensitization and allergy to cannabis sativa leaves in a population of tomato (lycopersicon esculentum)-sensitized patients.cases of allergy to cannabis sativa have occasionally been reported, but both the allergenic profile and eventual cross-reactivity pattern remain unknown.200818268387
revealing historic invasion patterns and potential invasion sites for two non-native plant species.the historical spatio-temporal distribution of invasive species is rarely documented, hampering efforts to understand invasion dynamics, especially at regional scales. reconstructing historical invasions through use of herbarium records combined with spatial trend analysis and modeling can elucidate spreading patterns and identify susceptible habitats before invasion occurs. two perennial species were chosen to contrast historic and potential phytogeographies: japanese knotweed (polygonum cuspid ...200818286192
comparison of the effects of artemisia vulgaris and artemisia absinthium growing in western anatolia against trichinellosis (trichinella spiralis) in rats.trichinellosis often causing diarrhea and more rarely fever, periorbital edema and myositis in human, is commonly treated with benzimidazole derivatives. the artemisia genus has been found to be effective against a variety of parasites. in the present study, the efficacy against trichinellosis (trichinella spiralis) of artemisia vulgaris and artemisia absinthium was examined for the first time in rats. the results of trichinoscopy and artificial digestion, during the enteral (adult) phase of the ...200818325496
oral allergy syndrome in patients with airborne pollen allergy treated with specific immunotherapy.according to literature, approximately 20%-70% of patients sensitized to pollen allergens experience oral allergy syndrome (oas) symptoms after eating raw fruits and vegetables. there is no standard treatment established for oas except avoiding implicated food. however, in patients with airborne pollen allergy treated with specific immunotherapy (sit), an improvement of oas symptoms has been reported in 30% to even 84% of individuals examined. the aim of the present study was to evaluate the pre ...200818358104
mass propagation and essential oil analysis of artemisia vulgaris.artemisia vulgaris l. (mugwort) is a threatened and valuable medicinal plant. attempts have been made in this research to mass propagate its plantlets through in vitro liquid culture technology using murashige and skoog (ms) basal medium supplemented with 6-benzyl adenine (ba) (0.44-8.88 microm). initially, 22.6 shoots (99.9% shooting frequency) developed from shoot tip explants cultured in ms with 4.44 microm ba at 100 ml flask capacity. this was further subcultured at increasing flask capacity ...200818397765
comparison between an intradermal skin test and allergen-specific ige-elisa for canine atopic dermatitis.the aim of this study was to compare the results of an intradermal skin test (idst) with those of an allergen-specific ige-elisa in 210 dogs with atopic dermatitis. all the dogs had a clinical diagnosis of atopic dermatitis and underwent an idst. the sera of all dogs were analysed for allergen-specific ige by elisa using the monoclonal antibody d9 against dog ige. idst was used as the standard assay. in both methods, the following antigens provided a positive test result: dermatophagoides farina ...200818429502
a new sesquiterpene from artemisia vulgaris.the dichloromethane extract of the air-dried leaves of artemisia vulgaris afforded a new sesquiterpene 1, caryophyllene oxide, phytyl fatty acid esters, squalene, stigmasterol and sitosterol. the structure of 1 was elucidated by extensive one- and two-dimensional nuclear magnetic resonance spectroscopy.200818438634
effect of an orally ingested mugwort and mushroom extract mixture on urine odor from aged mice.we had previously found that male mice could be trained to discriminate between the urine odor of aged and young adult (adult) mice. we hypothesized that these odors that characterized the older animals might be inhibited by a mixture of extracts (aam) of mugwort and mushroom, because previous studies have indicated that these extracts could be used to reduce the intensity of unpleasant body odors. the findings of this chemical study strongly suggest that the aam function helped to modify the ag ...200818460805
anaphylaxis to pine nut: cross-reactivity to artemisia vulgaris?the use of pine nuts, the seeds of pinus pinea, is on the increasing in the modern mediterranean diet. little more than 20 cases of allergy to this tree nut have been published, and cross-reactivity with pine pollen, peanut and almond has already been reported. we describe the case of a young boy with several episodes of anaphylaxis after pine nut ingestion. specific ige to pine nut and artemisia vulgaris was demonstrated by skin prick tests and in vitro determination of specific ige, although n ...200818479664
profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen.profilin, a pan-allergen present in all eukaryotic cells, is one of the main causes of cross-sensitization between pollen and plant-derived foods, but its clinical relevance as a food allergen is still debated.200818489029
[rare food allergies].a limited number of foods explain the majority of food allergies. these allergies can be due to a weak allergenicity (garlic, onion, potato), or a weak (or increasing) exposure to emergent food allergens which can be imported (exotic fruits), or recently introduced (lupin, buckwheat, sesame, inulin) or modified by the industry (lysats, lecithins, traces of antibiotics, caseinates, molds, dust mite). others are in relation with rarer cross-reactivity food allergy syndrome (apiaceae-compositae-mug ...200818557531
medicinal plant treatments for fleas and ear problems of cats and dogs in british columbia, canada.research conducted in 2003/2004 documented and validated (in a non-experimental way) ethnoveterinary medicines used by small-scale, organic livestock farmers in british columbia (bc), canada. interviews were conducted with 60 participants who were organic farmers or holistic medicinal/veterinary practitioners. a workshop was held with selected participants to discuss the plant-based treatments. this paper reports on the medicinal plants used for fleas in cats and dogs. fleas and flies are treate ...200818563443
molecular and immunological characterization of novel weed pollen pan-allergens.pan-allergens like profilins, calcium-binding proteins (cbps), and nonspecific lipid transfer proteins have been suggested as possible specific markers for multiple pollen sensitizations, and could be used to predict cross-sensitization/poly-sensitization to several pollen allergens. therefore, the purification and characterization of cross-reacting allergens in pollen is an extremely important task towards correct allergy diagnosis.200818588553
characterization of hla class ii/peptide-tcr interactions of the immunodominant t cell epitope in art v 1, the major mugwort pollen allergen.more than 95% of mugwort pollen-allergic individuals are sensitized to art v 1, the major allergen in mugwort pollen. interestingly, the cd4 t cell response to art v 1 involves only one single immunodominant peptide, art v 1(25-36) (kciewekaqhga), and is highly associated with the expression of hla-dr1. therefore, we investigated the molecular basis of this unusual immunodominance among allergens. using artificial apc expressing exclusively hla-drb1*0101 and hla-dra*0101, we formally showed that ...200818714038
symptoms to pollen and fruits early in life and allergic disease at 4 years of age.the predictive value of reported early symptoms to pollen or fruits on later allergic disease is unclear. our aim is to evaluate if symptoms to pollen and/or to fruits early in life are associated with allergic disease and sensitization to pollen at 4 years.200818721247
trends in prevalence of allergic rhinitis and correlation with pollen counts in switzerland.in recent decades, a large number of epidemiological studies investigating the change of prevalence of hay fever showed an increase in the occurrence of this disease. however, other studies carried out in the 1990s yielded contradictory results. many environmental factors have been hypothesized to contribute to the increasing hay fever rate, including both indoor and ambient air pollution, reduced exposure to microbial stimulation and changes in diets. however, the observed increase has not conv ...200818751737
antinociceptive peripheral effect of achillea millefolium l. and artemisia vulgaris l.: both plants known popularly by brand names of analgesic drugs.the hydroalcohol extracts of achillea millefolium l. (am) and artemisia vulgaris l. (av), both belonging to the asteraceae family, were evaluated by the hot plate, writhing, formalin and intestinal transit tests in an attempt to confirm their folk use as analgesic, antiinflammatory and antispasmodic agents. am 500 and 1000 mg/kg significantly inhibited abdominal contortions by 65% and 23%, respectively, whereas av 500 and 1000 mg/kg inhibited them by 48% and 59%, respectively. none of the extrac ...200918844327
array-based profiling of ragweed and mugwort pollen allergens.ragweed (ambrosia artemisiifolia) and mugwort (artemisia vulgaris) pollen is the main cause of allergic reactions in late summer and autumn. the differential diagnosis between ragweed and mugwort pollen allergy is a frequent problem encountered by allergologists in areas where both plants are present due to shared antigenic structures and overlapping flowering seasons.200818925891
characterization of antioxidant activity of extract from artemisia vulgaris.recent investigations have shown that the antioxidant properties of plants could be correlated with oxidative stress defense and different human diseases. in this respect flavonoids and other polyphenolic compounds have gained the greatest attention. the present study was undertaken to evaluate the in vitro and in vivo antioxidant activities of aqueous extract of artemisia vulgaris. the plant extract was tested for dpph (2, 2-diphenyl, 2-picryl hydrazyl) radical scavenging, nitric oxide radical ...200818930849
populations of xylella fastidiosa in plants required for transmission by an efficient vector.abstract xylella fastidiosa, a xylem-limited bacterium that causes pierce's disease (pd) of grapevine and other diseases, is transmitted efficiently by xylem-feeding leafhoppers. acquisition of a pd strain of x. fastidiosa by the blue-green sharpshooter (bgss) from five plant host species-grapevine (vitis vinifera), himalayan blackberry (rubus discolor), california mugwort (artemisia douglasiana), watergrass (echinochloa crus-galli), and bermuda grass (cynodon dactylon)-was tested at various tim ...199718945018
[age features of the allergens in allergic rhinitis patients of different age in hubei area].to investigate the distribution of positive allergens in patients with allergic rhinitis and the discrepancy among different age group.200818950005
stereostructure assignment of medium-sized rings through an nmr-computational combined approach. application to the new germacranes ketopelenolides c and d.the new germacrane derivatives ketopelenolides c and d have been isolated from great mugwort (artemisia arborescens). their stereostructure elucidation exemplifies some of the most common pitfalls facing the configurational assignment of medium-sized polyfunctionalized compounds. it was established through a combined strategy including chemical derivatization, nmr data analysis, molecular modeling, and quantum-mechanical calculations including a comparison between experimental 13c nmr data and a ...200819007284
clinical, anamnestic and serological features of peach allergy in portugal.peach is a common food allergen source throughout europe. the aim of this study was to characterize peach allergy in a portuguese patient population.200919033734
anaphylactic reaction to camomile tea.a type-iv-allergic reaction to german camomile (matricaria chamomilla) in a form of allergic contact dermatitis is not unusual. however, only a few cases of anaphylactic reaction to camomile have been described in the literature.200919050375
immune recognition of novel isoforms and domains of the mugwort pollen major allergen art v 1.allergen isoforms can differ in their ige and t cell recognition patterns, and thus might have an impact on the selection of candidates for molecule-based diagnostic and therapeutic approaches. the present study aimed at the identification and characterization of isoforms of art v 1, the mugwort pollen major allergen. in addition, single art v 1 domains were physicochemically and immunologically characterized. for this purpose, the art v 1 cdna was radiolabeled and used to screen a mugwort polle ...200919054564
allergen-specific ige measurement with the immulite 2000 system: intermethod comparison of detection performance for allergen-specific ige antibodies from korean allergic patients.intermethod comparison between immulite 2000 chemiluminescent enzyme immunoassay (cleia) and the established cap test for allergen-specific ige (sige) has only been evaluated by a few studies.200919056369
allergenicity and immunogenicity of the major mugwort pollen allergen art v 1 chemically modified by acetylation.treating allergies with modified allergens is an approach to make the treatment safer and more efficient. art v 1 is the most prominent allergen of mugwort pollen and a significant cause of hayfever around europe. the aim of this study was to reduce the allergenicity of art v 1 by acetylation, and to investigate the capacity of the modified protein to generate blocking antibodies.200919178539
sensitisation to ambrosia in switzerland: a public health threat on the wait.ambrosia artemisiifolia (short name = ambrosia common ragweed) pollen is a potent allergen and has recently been found in switzerland, spreading from the southwest of the country. the aim of this study is to describe ambrosia sensitisation rates in the population-based sapaldia cohort (swiss study on air pollution and lung diseases in adults) and to test whether an increase in these rates could be observed.200919204839
a multicentre study assessing the prevalence of sensitizations in patients with asthma and/or rhinitis in china.the prevalence of sensitization in patients with asthma and rhinitis in mainland china remains unclear.200919210346
3-layer-based analysis of peptide-mhc interaction: in silico prediction, peptide binding affinity and t cell activation in a relevant allergen-specific model.cd4+ t cells recognize peptides bound to major histocompatibility complex (mhc) class ii molecules on the surface of antigen presenting cells by their t cell receptor (tcr). using a well-characterized allergen-specific model we studied peptide/mhc (pmhc) interactions by combining computational methods with experimental analyses. a 12-mer and an 18-mer peptide, both containing the human leukocyte antigen (hla)-dr1-restricted, immunodominant t cell epitope of art v 1, the major mugwort pollen alle ...200919232439
effect of artemisia vulgaris rhizome extracts on hatching, mortality, and plant infectivity of meloidogyne megadora.the activity of an ethanolic rhizome extract of artemisia vulgaris against hatching, mortality, host plant infectivity, and galling of the root-knot nematode meloidogyne megadora was investigated. the extract inhibited egg hatch (50% inhibition by 2.35mg/ml) and caused second-stage juvenile mortality (50% lethality at 12 hours' exposure to 55.67 mg/ml), both in a dose-dependent manner. nematode infectivity on phaseolus vulgaris 'bencanta trepar', a susceptible host, decreased in a dose-responsiv ...200319262777
inhibitory effect of essential oils obtained from plants grown in colombia on yellow fever virus replication in vitro.an antiviral drug is needed for the treatment of patients suffering from yellow fever. several compounds present in plants can inactive in vitro a wide spectrum of animal viruses.200919267922
[evaluation of relationships between foods and pollen antigens in peach oral allergy patients -serous specific ige levels of peach recombinant antigen-].evaluation of the relationships between foods and pollen allergens in oral allergy syndrome (oas).200919329876
role of the polypeptide backbone and post-translational modifications in cross-reactivity of art v 1, the major mugwort pollen allergen.artemisia vulgaris (mugwort) is one of the main causes of late summer pollinosis in europe, with >95% of patients sensitized to the glycoallergen art v 1. despite the importance of this allergen, little is known about its cross-reactive behavior. here we investigated the occurrence of conserved art v 1 antigenic determinants in sources known to display clinically relevant cross-reactivity with mugwort pollen. for this purpose, monoclonal antibodies specific for a cysteine-stabilized epitope of t ...200919361284
does the burning of moxa (artemisia vulgaris) in traditional chinese medicine constitute a health hazard?concerns have been expressed about potential toxicity of the smoke produced by the burning of moxa in traditional chinese medicine. with the advent of strict anti-smoking legislation in the uk, it was decided to test the volatiles produced by moxibustion and compare them with current agreed safe exposure levels.200919369189
isoform identification and characterization of art v 3, the lipid-transfer protein of mugwort pollen.art v 3, the lipid-transfer protein (ltp) of artemisia vulgaris pollen is a relevant allergen showing frequent cross-reactivity with homologues in other plants. here we report the identification of four full-length art v 3 sequences obtained by cdna cloning using mass spectrometry-based sequencing. two isoforms, art v 3.0201 and art v 3.0301 were expressed as soluble proteins in escherichia coli rosetta-gami b(de3) plyss using different expression systems. purified natural and recombinant art v ...200919406480
modulation of allergen-specific t-lymphocyte function by virus-like particles decorated with hla class ii molecules.t(h)2 lymphocytes play an important role in the induction and maintenance phase of type i allergy. modulation of the responses of t(h)2 lymphocytes by novel forms of antigen-presenting platforms may help shape the immune response to allergen and palliate allergic diseases.200919500826
sequence-specific 1h, 15n and 13c resonance assignments of art v 1: a proline-rich allergen of artemisia vulgaris pollen.art v 1 is the major allergen of artemisia vulgaris. the ige raised against art v 1 not only can cross-react with other proteins from the asteraceae family members but also with components of various forms of food. art v 1 is an important target for immunotherapy strategies, including vaccination with hypoallergenic derivatives or chimeras. we report the (1)h, (13)c, and (15)n resonance assignments of the recombinant art v 1 and identification of secondary structures based on (13)c chemical shif ...200919636957
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