Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| the ph-dependence of the non-specific esterase activity of carboxypeptidase a. | the hydrolysis of the following 6 esters by bovine pancreatic carboxypeptidase a (peptidyl-l-amino-acid hydrolase, ec 3.4.12.2) has been investigated over the range ph 5--10 at 25 degrees c, ionic strength 0.2: ch3co2chrco2h (r = c6h5 (ester 3), c6h5ch2 (ester 4), 4-no2c6h4co2chrco2h (r = c6h5 (ester 5), c6h5ch2 (ester 6), ch3(ch2)2 (ester 7)), ch3ch2co2ch(ch2c6h5)-co2h (ester 9). for each ester the ph dependence of kcat/km indicates that substrate binding is controlled by an acid of pkeh = 9.2 ... | 1978 | 31187 |
| isolation of anaerobes in ludwig angina. | 1979 | 31420 | |
| self-poisoning in auckland reconsidered. | data is presented describing 345 self-poisoners presenting at the accident and emergency department and 211 referred to the psychiatric liaison service at auckland hospital during the 12 month period between august 1976 and july 1977. both groups show the age and sex distribution commonly seen in self-poisoning, with a preponderance of young females. referral rates increased with age and with the implication of anti-depressants, neuroleptics and anticonvulsants. only 20 percent of the referred p ... | 2001 | 31581 |
| [application of the main components method to studying the character of the distribution of humoral antibacterial antibodies in patients with chronic bronchitis and bronchial asthma]. | 1978 | 31749 | |
| [studies on staphylococcal enterotoxin b. ii. production and regulation (author's transl)]. | enterotoxigenic strain of staphylococcus aureus (atcc 14458) was grown under various conditions with constant shaking to determine the requirements for maximum toxin production. it was evident that 3% tryptic soy broth, 3% nz-amine nak + 3% casein hydrolysate, 3% nz-amine nak + 1% yeast extract, and 3% nz-amine nak + 1% yeast extract + 0.2% glucose are most available toxin production media. but concentration of glucose could strictly triggered the enterotoxin producing efficiency. when glucose c ... | 1978 | 32015 |
| peptide bond synthesis catalyzed by alpha-chymotrypsin. | alpha-chymotrypsin [ec 3.4.21.1] catalyzed the syntheses of peptide bonds with various n-acylated amino acids or peptides having aromatic or hydrophobic amino acid residues at the c-terminal position as carboxyl components, and amino acid derivatives, peptides or their derivatives as amine components. a neutral ph was most efficient and quite high concentrations of alpha-chymotrypsin and starting materials were required for synthesis. four amine components, hydrophobic or bulky amino acid residu ... | 2001 | 32179 |
| atherosclerosis--disease of old age or infancy? | 2001 | 32191 | |
| wet mass shear strength and tablet dissolution [proceedings]. | 2001 | 32276 | |
| effect of lipophilicity of ionisable drugs on deviations from expected ph-partition behaviour [proceedings]. | 2001 | 32305 | |
| acute suppurative parotitis caused by anaerobic bacteria: report of two cases. | staphylococcus aureus is the predominant pathogen in acute suppurative parotitis. although anaerobic bacteria are prevalent in the normal oral and upper respiratory tract flora and frequently are involved in oral and facial infections, they have seldom been isolated from patients with suppurative parotitis. it may be that a role for anaerobes in parotitis has not been documented because of inadequate specimen transport or anaerobic culture techniques. we describe two cases of acute suppurative p ... | 1978 | 32513 |
| injury to staphylococcus aureus during sausage fermentation. | staphylococcus aureus 196e added to a beef sausage containing starter culture and 0.5 to 2.0% glucose and incubated at 35 degrees c was unable to grow when plated on tryptic soy agar (tsa) containing 7.5% nacl. the injury, presumed to be due to the lactic acid produced during fermentation, was more pronounced at the lower concentrations of glucose (and lower acid levels). in the absence of glucose and/or starter culture, no injury was observed. when sausages containing s. aureus injured by ferme ... | 1978 | 32835 |
| effect of leukocyte hydrolases on bacteria. x. the role played by leukocyte factors, cationic polyelectrolytes, and by membrane-damaging agents in the lysis of staphylococcus aureus: relation to chronic inflammatory processes. | a heat-stable factor present in extracts of human blood leukocytes is capable of lysing young staphylococcus aureus at ph 5.0. lysis is characterized by breakdown of cell-wall components as judged by electron microscopic and biochemical analysis. the leukocyte extracts can be replaced by a variety of agents known to injure cell membranes, e.g., leukocyte cationic protein histone, polymyxin b, colimycin, phospholipase a, and lysolecithin. the mechanisms by which all these agents bring about the d ... | 1977 | 33120 |
| fluorimetric assay of cefoxitin. | 1979 | 33143 | |
| genetic analysis of staphylococcus aureus rna polymerase mutants. | spontaneous mutants of staphylococcus aureus resistant to rifampin, rifamycin sv, streptovaricin, or streptolydigin were isolated and shown to be resistant due to chromosomal rather than plasmid mutations. based on data concerning spontaneous mutation rates, genetic cotransduction rates, and in vitro sensitivity studies, four major antibiotic cross-resistance patterns were found. the genetic markers responsible for these cross-resistance patterns were shown to be separable by transduction. nonpu ... | 1979 | 33150 |
| a comparison by 220-mhz nmr of histidine hydronium ion titrations in porcine pancreatic ribonuclease and an extensively deglycosylated derivative. | 220-mhz nmr was used to observe the titration behavior of the 5 histidine residues in porcine pancreatic ribonuclease (ribonucleate pyrimidine-nucleotido-2'-transferase (cyclizing), ec 3.1.4.22) and a derivative prepared by removal of 80% of the attached carbohydrate from this glycoprotein. resonances due to histidine c-2 protons were observed over the full ph range for 3 of the residues; such resonances for the remaining 2 histidine residues broadened out as the ph was increased. resonances due ... | 1979 | 33180 |
| in vivo activity of amoxicillin and ampicillin against gram-positive bacteria: results of prophylactic studies. | in prophylactic treatment of intraperitoneal infections with streptococcus pneumoniae (types 1 and 2) and streptococcus pyogenes in mice, amoxicillin had a definite advantage over ampicillin in terms of protective effect. when the infecting agent was given to mice so as to produce an infection in the brain or lung (for example, s. pneumoniae given intracranially or intranasally), amoxicillin was also more effective prophylactically than ampicillin. | 1978 | 33219 |
| physiological pharmacokinetics of beta-lactam antibiotics: penicillin v distribution and elimination after intravenous administration in rats. | 1979 | 33246 | |
| [sessions of the 18th meeting of the japanese society of nuclear medicine. abstracts]. | 2001 | 33285 | |
| dopamine and chronic antipsychotic drug treatment. | 1979 | 33409 | |
| [established cell lines expressing differentiated characters of liver cells (author's transl)]. | 1978 | 33421 | |
| relief of postoperative pain with intercostal blockade compared with the use of narcotic drugs. | 1999 | 33521 | |
| effect of growth conditions on the antigenic components of streptococcus mutans and lactobacilli. | 1) the release of lta from chemostat-grown cultures of s. mutans and l. fermentum is dependent on the generation time and ph. 2) the growth rate affects the immunogenicity of lta and the wall polysaccharide of l. fermentum. 3) the growth of l. plantarum under glucose limitation influences the glucose content of the wall teichoic acid. the composition of the wall polysaccharide of s. mutans ingbritt may also be changed under these conditions. 4) the conditions of autoclaving used to release cell ... | 1978 | 33543 |
| bacterial allergy in allergic rhinitis and bronchial asthma. | nineteen patients suffering from allergic rhinitis and bronchial asthma were studied for bacterial allergy with staphylococcus aureus, kelbsiella pneumoniae and diplococcus pneumoniae. allergy skin tests, provocative tests and the migratory inhibition factor were employed. the correlation indicates to the authors that bacterial allergy is more important than bacterial "infection" as a cause of allergic rhinitis and asthma in many instances. this is often overlooked by practicing allergists. | 1979 | 33586 |
| laboratory studies with bl-s 578 (cefadroxil) a new broad-spectrum orally active cephalosporin. | bl-s 578 (cefadroxil) is a new orally active semisynthetic cephalosporin antibiotic with broad-spectrum antibacterial activity. the new compound was evaluated in vitro in comparison with cephalexin. some properties studies such as, antibacterial activity, binding with serum proteins and stability in acid and neutral solution at 37 degrees c for both cephalosporins were similar. in experimental infections of mice, the protective action of bl-s 578 was more effective than cephalexin against staphy ... | 1979 | 33784 |
| ph dependency of kinetic parameters and reaction mechanism of beef liver catalase. | the ph-dependence of the kinetic parameters in h2o2 decomposition by beef liver catalase was investigated. at ph 7.0, the ternary complex (ess) decomposition rate was about 100 times faster than ess formation (42 microm h2o2), and the value of the michaelis constant was 0.025 m. from ethanol competition experiments, two different proton dissociation constants of the enzyme (pke1 = 5.0, pkes2 = 5.9) were obtained for the binding of first and second h2o2 molecules. another pka value (pkes1) of 4.2 ... | 1979 | 33977 |
| glycoproteins and blood group activity. oligosaccharides of a+ hog submaxillary glycoproteins. | 1979 | 33982 | |
| influence of cultivation conditions on the production of staphylocoagulase by staphylococcus aureus 104. | high yields of staphylocoagulase from staphylococcus aureus 104 were obtained in a simple salts medium supplement with glycerol, casein hydrolysate and three vitamins. conditions of oxygen-limitation (dissolved oxygen concentration less than 2%), a ph of 7.4, a temperature of 35 degrees c and a 1 in 10 inoculum of overnight culture were required for optimal yields of staphylocoagulase. | 1978 | 34009 |
| solubility of doxycycline in aqueous solution. | the solubility of doxycyline monohydrate and doxycycline hydrochloride dihydrate was investigated in aqueous solution. the hydrochloride dihydrate salt was isolated and identified from solutions initially containing doxycycline hyclate in water. the pka' = 3.09 (mu = 0.1 and 25 degrees) for protonation of doxycycline was determined spectrophotometrically. the ph-solubility profiles were determined for doxycycline monohydrate in water and in 1.0 m nano3-hno3 and nacl-hcl. the ph-solubility profil ... | 2000 | 34018 |
| kinetics and mechanism of hydrolysis of 1-(2'-acetoxybenzoyl)-2-deoxy-alpha-d-glucopyranose, a novel aspirin prodrug. | the formation rate of aspirin from the prodrug was determined as a function of the ph, temperature, and dielectric constant of the solvent spectrophotometrically and was confirmed by high-pressure liquid chromatography. aspirin formation was first order with respect to the prodrug and zero order with respect to the hydroxide-ion concentrations. the hydrolysis rate was independent of buffer concentration but very sensitive to the dielectric constant of the solvents. the half-life for the formatio ... | 2000 | 34021 |
| modulation of neuronal activity by peptides and neurotransmitters: possible role of cyclic nucleotides. | 2000 | 34033 | |
| on the correlation between alpha-adrenoceptor blockade and inhibition of neuronal uptake of 3h-noradrenaline. | 1979 | 34177 | |
| [use of frozen thrombocytes for the determination of von willebrand factor with the aid of ristocetin]. | the quantitative assay of von willebrand factor using ristocetin aggregation is simplified and improved by the use of frozen normal platelets. the main advantages of the method described are excellent reproducibility, maintenance of a stable optimal ph and the possibility of eliminating interfering factors, such as inhibitors, by dilution. | 1999 | 34214 |
| potentiometric titration behavior of a copolymer of glutamic acid and alanine prepared by thermal polycondensation. | 2001 | 34446 | |
| limited proteolysis of glutamine synthetase is inhibited by glutamate and by feedback inhibitors. | limited proteolysis of glutamine synthetase from escherichia coli has been studied under nondenaturing conditions (ph 7.6, 20 degrees c). trypsin cleaves the polypeptide chain of glutamine synthetase into two principal fragments, mr = about 32,000 and 18,000. the covalently bound amp group is attached to the larger fragment and its presence does not affect cleavage. although the cleaved polypeptide chain does not dissociate under nondenaturing conditions, catalytic activity is lost. chymotrypsin ... | 1979 | 34614 |
| chromogenic cephalosporin spot test to detect beta-lactamase in clinically significant bacteria. | lactamase production. reacteroides melaniongenicus, 14 | 1979 | 34624 |
| the nasopharyngeal culture in acute otitis media. a reappraisal of its usefulness. | simultaneous cultures of the nasopharynx and middle ear exudate (obtained by tympanocentesis) were obtained from 225 children (mean age, 34 months; median age, 41 months) with suppurative otitis media. a 72% prediction rate for middle ear pathogens was obtained by examining the nasopharyngeal cultures after the strict observance of two essential prerequisites: (1) the nasopharyngeal culture was immediately plated on appropriate solid agar and (2) a semiquantitative method for bacterial enumerati ... | 1979 | 34739 |
| osmotic flow of water in isolated frog gastric mucosa. | a gravimetric procedure was used to measure net volume flow across bullfrog gastric mucosa mounted between chambers. a portion of the net volume flow towards the lumen was coupled to acid production. with an isotonic solution instilled on the luminal surface, the secreted acidity (ratio of increase in acid output to increase in volume flow) was hypertonic, in agreement with previous reports in mammalian stomach. dilution of the secretory solution to 10% of normal nearly abolished the net volume ... | 1998 | 35007 |
| salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis. | aspirin profoundly inhibited the in vitro augmentation of human and mouse granulocyte adherence to nylon fiber induced by the bacterial products escherichia coli endotoxin and staphylococcus aureus culture filtrate. granulocytes obtained from normal volunteers during the 48 hr following ingestion of aspirin did not respond normally to endotoxin stimulation. furthermore, pretreatment of mice with sodium salicylate prior to intraperitoneal infection with streptococcus pneumoniae impaired granulocy ... | 1979 | 35259 |
| [the bacterial flora of preputial space]. | the bacterial flora of the preputial space of 210 healthy males (43 children aged between 2 and 11 years, 137 males between 12 and 60 years and 30 men over 60 years) was determined by smears and cultueres from glans penis, sulcus coronarius and the adjacent prepuce. the results were grouped according to various criteria, e.g. glans covered or uncovered and age of males. differences in the distribution of germs could be found in relationship to age. in the case of an uncovered glans penis the pre ... | 1979 | 35486 |
| effect of storage at 1 degree and 4 degrees c on viability and injury of staphylococcus aureus, escherichia coli and streptococcus faecalis. | 1979 | 35509 | |
| etiology and antimicrobial therapy of acute maxillary sinusitis. | eighty-one adults with symptoms of acute sinusitis were studied by direct needle puncture and aspiration of the maxillary sinus (105 sinuses). fifty-nine bacterial strains were isolated in titers of greater than or equal to 10(4) colony-forming units/ml; streptococcus pneumoniae and haemophilus influenzae accounted for 64% of the isolates. other bacteria recovered included anaerobes (12%), neisseria species (8.5%). streptococcus pyogenes (3%), alpha-hemolytic streptococcus (3%), non-group a beta ... | 1979 | 35571 |
| factors causing the clumping reaction of streptococcal strains with human plasma. | fresh isolates of 204 strains of streptococcus haemolyticus, 75 strains of viridans group streptococcus, and 45 strains of streptococcus pneumoniae were studied for their clumping reactions with human plasma. the plasma and serum factors that clumped the streptococcal strains were compared with those that clumped a staphylococcus aureus strain. one hundred eleven strains of s. haemolyticus, 10 strains of viridans group streptococcus, and none of the strains of s. pneumoniae tested were clumped b ... | 1979 | 35572 |
| studies on the relationship between the degradative rates of proteins in vivo and their isoelectric points. | acidic proteins tend to be degraded more rapidly than neutral or basic proteins in rat liver, skeletal muscle, kidney and brain and in mouse liver and skeletal muscle. we now report a similar relationship among soluble proteins from rat lung, heart and testes, and from human fibroblasts and mouse-embryo cells grown in culture. these findings indicate that the correlation between protein net charge and degradative rate is a general characteristic of intracellular protein degradation in mammals. t ... | 1979 | 36075 |
| a microcalorimetric study on the action of penicillins on staphylococcus aureus and escherichia coli. | the heat generated by cultures of a strain of escherichia coli and of a beta-lactamase- and a non-beta-lactamase-producing strain of staphylococcus aureus were registered by a flow microcalorimeter of the heat conduction type. when exposing the non-beta-lactamase-producing strain to benzylpenicillin, an effect that appeared to correspond to the 'paradoxical zone phenomenon' was found, i.e. the inhibitory effect on the bacterial metabolism, as judged from the heat generated, was smaller when usin ... | 1979 | 36262 |
| use of the chief component method for classifying clinical physiological observations. | 1979 | 36344 | |
| the microbiology of serous and mucoid otitis media. | one hundred forty-four serous and mucoid effusions were cultured for aerobic bacteria, mycoplasma pneumoniae, and virus. thirty percent of all effusions yielded an unequivocally positive culture for aerobic bacteria. although serous effusions were culture positive as often as mucoid effusions, haemophilus influenzae was isolated predominantly from serous effusions and staphylococcus epidermidis predominantly from mucoid samples. only one of 73 effusions yielded a viral isolate (herpesvirus homin ... | 1979 | 36591 |
| new indications for old antibiotics: tetracycline, erythromycin, carbenicillin, and vancomycin revisited. | 1979 | 36669 | |
| otitis media with effusion. cytological and microbiological correlates. | a quantitative cytologic study of 83 middle ear effusions from children with otitis media with effusion (ome) was made with the use of cytocentrifuge-prepared smears and was correlated with bacteriological findings. the identification of the types of cell present in an effusion was confirmed by electron microscopic findings. the most common cell types were neutrophilic leukocytes, lymphocytes, and macrophages, but a few eosinophils were found in only one case. the cytologic profile of an effusio ... | 1979 | 36875 |
| purification and partial characterization of an antibiotic produced by myxococcus coralloides. | a strain of myxococcus coralloides producing an antibiotic capable of inhibiting growth of gram-positive bacteria was isolated. antibiotic production occurred during vegetative growth but not during myxospore formation. the antibiotic was extracted from the growth medium with chloroform and purified by adsorption on silicic acid and by preparative silica gel thin-layer chromatography. the purified antibiotic showed a resistance to heat, acid, alkali and proteolytic enzymes. chromatographic and e ... | 1979 | 37227 |
| ultrastructure of graniferous tracheary elements in the haustorium of exocarpus bidwillii, a root hemi-parasite of the santalaceae. | the xylem in the body of the haustorium of e. bidwillii has the shape of an inverted conical flask with the expanded portion being known as the vascular core. the tracheary elements of the vascular core are notable for the occurrence of numerous granules within their lumina and the presence of mostly imperforate walls. elsewhere in the haustorium graniferous tracheary elements are absent and the cells are usually ordinary vessel elements. thin sections for transmission electron microscopy, post- ... | 2001 | 37519 |
| hairy cell leukemia: differences in phagocytic capacity of cells in vitro. | hairy cells from eight patients with hairy cell leukemia were evaluated with both light and transmission electron microscopy for their capacity to phagocytose zymosan, latex, staphylococcus aureus, and pseudomonas aeruginosa. in two patients, there was no phagocytosis of any of these substances; cells from three patients phagocytosed only latex; two, all except pseudomonas; and one, all 4 substances. hairy cells became relatively smooth while in culture with staphylococcus, but no surface change ... | 1979 | 37638 |
| bactericidal action of an average dose of erythromycin in the bronchi. | a study was carried out to establish whether erythromycin stearate was bacteriostatic or bactericidal at the concentrations reached in the bronchial secretion. twenty-two patients suffering from an acute attack of chronic bronchitis, sustained by streptococci, diplococci, staphylococci or h. influenzae sensitive to erythromycin, were treated with 1500 mg erythromycin per day until symptoms regressed, usually within 3 to 5 days. the results showed that after treatment there was a dramatic reducti ... | 1979 | 38063 |
| ps-5, a new beta-lactam antibiotic. ii. antimicrobial activity. | ps-5, a new beta-lactam antibiotic, has relatively potent antimicrobial activity against gram-positive and gram-negative bacteria, especially the enterobacter groups, serratia marcescens, the proteus groups and klebsiella pneumoniae. the activity of ps-5 against many beta-lactamase-producing organisms is greater than that of cefoxitin or cefazolin. ps-5 has good therapeutic activity in mice infected with staphylococcus aureus smith or enterobacter cloacae 45. | 1979 | 38238 |
| biological characteristics of peptidoglycans of group a streptococcus and some other bacterial species. ii. immunological mechanisms involved in thrombocytolysis. | immunological mechanisms are involved in the thrombocytolytic activity of peptidoglycan of group a streptococcus, streptococcus pneumoniae and staphylococcus aureus. inactivation of particular components of complement (heating of blood serum to 56 degrees c,incubation with zymosan or nh4oh) inhibited the thrombocytolytic activity of group a streptococcus peptidoglycan. so did preincubation of group a streptococcus peptidoglycan with homologous antipeptidoglycan antibody. on the other hand, antib ... | 1978 | 38280 |
| detection of experimental bacteremia and fungemia by examination of buffy coat prepared by a micromethod. | rabbits received intravenous injections of bacteria or fungi, and a comparison was made of the abilities of broth cultures, plating after dilution either in saline solution or in distilled water containing triton x-100, and buffy coat examinations to detect the organisms in heart blood. the most sensitive method was broth culture. by microscopy or subculture of buffy coat cells prepared by centrifugation of blood in microhematocrit tubes, organisms were rapidly and regularly detected when their ... | 1979 | 38662 |
| bactericidal and bacteriostatic action of chloramphenicol against memingeal pathogens. | the bacteriostatic and bactericidal effects of chloramphenicol, ampicillin, tetracycline, and sulfisoxazole were compared against several potential meningeal pathogens. chloramphenicol is bactericidal at clinically achievable concentrations against haemophilus influenzae, streptococcus pneumoniae, and neisseria meningitidis. it is bacteriostatic against gram-negative bacilli of the family enterobacteriaceae and against staphylococcus aureus. chloramphenicol has proven highly efficacious in the t ... | 1979 | 38742 |
| the inhibition of staphylococcal beta-lactamase by clavulanic acid. | clavulanic acid inhibited both the extracellular and cell-extract beta-lactamases of the four staphylococcus aureus strains tested. the inhibition of s. aureus russell cell-extract enzyme appeared to be active-site-directed and proceeded in a first-order fashion consistent with the formation of a covalent intermediate. inhibited enzyme free of excess clavulanic acid was shown to regenerate enzyme activity slowly at ph 7.0, but the rate of reactivation increased at acid ph. when the enzyme was in ... | 1979 | 38773 |
| use of staphylococcus aureus for rapid radioimmunoassay of influenza a virus haemagglutinin. | in a rapid method for the radioimmunoassay (ria) of influenza a virus haemagglutinin, staphylococcus aureus (strain cowan i, czechoslovak state collection no mau 55/64) was used for separation of bound and free antigens. with rabbit and human immune sera, the binding of antigen-antibody complexes to heat-killed, formalin-fixed staphylocci was comparable to the double antibody technique. the time required for the completion of binding reaction was about 10 min compared to 18--24 hr required for d ... | 1979 | 39433 |
| a rapid sensitive assay for specific protein synthesis in cells and in cell-free translations: use of staphylococcus aureus as an adsorbent for immune complexes. | 1979 | 39469 | |
| magnesium and iron addition to casein hydrolysate medium for production of staphylococcal enterotoxins a, b, and c. | from comparisons of 4% n-z amine nak made with distilled water, naturally hard water, and synthetic salt solutions, it appeared that magnesium and, to a lesser extent, iron were limiting factors in the production of staphylococcal enterotoxins b and c but not a. maximum enterotoxin production with nak medium was achieved by the addition of 5 mg of mg2/ per liter (for a total of 9 mg of mg2+ per liter) and 0.5 mg of fe2+ per liter. higher levels of magnesium were not inhibitory. supplementing nak ... | 1979 | 39506 |
| induction and delayed activation of tyrosine hydroxylase in noradrenergic neurons of a1 and a2 groups of medulla oblongata of rat. | 1979 | 39662 | |
| oxidative deamination of thialysine by snake venom l-aminoacid oxidase. | thialysine is oxidatively deaminated by snake venom l-aminoacid oxidase at alkaline ph. the oxygen consumption curves show a characteristic diphasic course: the quick uptake of half a mole of oxygen per mole of substrate, in aggreement with a typical oxidative deamination, is followed by a slow extra oxygen consumption. the first product of the reaction is the corresponding alpha-oxo-epsilon-amino acid, which spontaneously cyclizes to the internal schiff base 5-6-dihydro-delta 3,1,4-thiazin-3-ca ... | 1978 | 39901 |
| polymicrobial bacteremia. | of 26,961 blood cultures taken during an 18-month period at the cincinnati general hospital, 1,715 (6%) were positive. ninety-four patients had blood cultures containing more than one organism. although aerobic and anaerobic streptococci were the most frequently isolated bacteria, a variety of microorganisms, including staphylococcus aureus and the klebsiella-enterobacter-serratia group, was isolated in different combinations depending on the underlying disease. neurological illness, malignant n ... | 1979 | 40048 |
| [synergism]. | 1979 | 40123 | |
| pollution of the sea and its effects. | marine pollution has been studied under the following groupings of effects; harm to living resources, hazards to human health, reduction of amenities and interference with other users of the sea. this paper is concerned mainly with the first two categories and their interrelation. apart from certain seabirds affected by oil, the major stocks of marine animals show no evidence of reduction by pollution. pollution effects are generally insignificant in relation to other factors governing reproduct ... | 1979 | 40238 |
| the laminar organization of optic nerve fibres in the tectum of goldfish. | potentials in the tectum of large (12--20 cm) goldfish, evoked by stimulation of the optic nerve, were recorded extracellularly with double-barrelled electrodes (d.c., saline and a.c., woods metal--pt). four fibre groups (e, m1, m2, m3) were recorded at latencies of approximately 2, 3, 5 and 8 ms after stimulation (conduction velocities of approximately 7, 5, 3 and 2 m/s). the same four groups were recorded from the optic nerve when the tectum was stimulated. the fastest fibre groups (e) did not ... | 1996 | 40252 |
| [digital computer analysis of the electromyogram: preliminary report (author's transl)]. | this is a preliminary report of a method of digital computer analysis of the electromyogram recorded from twenty sites in biceps brachial during fixed voluntary effort. the method allows several emg parameters to be studied. the results in a group of normal subjects have been compared with those in patients with neuromuscular disease. three parameters have proved of value in differentiating normal subjects from those with neurogenic disease. | 1995 | 40295 |
| oxidation of l-glucose by a pseudomonad. | a new enzyme, d-threo-aldolse dehydrogenase (2s,3r-aldose dehydrogenase), found in pseudomonas caryophylli, was capable of oxidizing l-glucose l-xylose, d-arabinose, and l-fucose in the presence of nad+. the enzyme was synthesized constitutively and purified about 120-fold from d-glucose-grown cells. the km values for l-glucose, l-xylose, d-arabinose, and l-fucose were 1.5 . 10(-2), 4.5 . 10(-3), 2.8 . 10(-3), and 2.1 . 10(-3), respectively. d-glucose and other aldoses inhibited the enzyme react ... | 1979 | 40609 |
| proceedings of the association of european pediatric cardiologists. xvith annual general meeting, 9--12 may 1978, budapest, hungary. abstracts. | 1979 | 40796 | |
| bacterial adherence to pharyngeal cells in smokers, nonsmokers, and chronic bronchitics. | selective adherence to host mucosal surfaces is probably a requirement for colonization and infection by bacteria. since pharyngeal colonization may be an important determinant in the pathogenesis of pneumonia, we studied the adherence of 10 different bacteria to pharyngeal cells obtained from nonsmokers, smokers, and chronic bronchitics. various patterns of adherence among the different groups of subjects were found. young healthy smokers had increased adherence of streptococcus pneumoniae type ... | 1979 | 40879 |
| [a bacteriological investigation of acute purulent otitis media (author's transl)]. | 1979 | 41035 | |
| carazolol, an extremely potent beta-adrenergic blocker: binding to beta-receptors in brain membranes. | 1979 | 41147 | |
| anaerobic isolates in chronic recurrent suppurative otitis media. treatment with carbenicillin alone and in combination with gentamicin. | tympanocentesis was performed in 32 pediatric patients with chronic recurrent suppurative otitis media. the aspirate was cultured aerobically and anaerobically. aerobes were isolated from ten patients (31.2%); anaerobes from one patient; and both aerobes and anaerobes from 21 patients (65.6%). there were 46 aerobic isolates. the aerobes commonly recovered were pseudomonas aeruginosa (24 isolates) proteus sp. (5) and staphylococcus aureus (3). there were 32 anaerobes isolated including anaerobic ... | 1979 | 41811 |
| comparative adsorption of human enteroviruses, simian rotavirus, and selected bacteriophages to soils. | virus adsorption to soils is considered to be the most important factor in removing viruses after land treatment of wastewater. most of the studies on virus adsorption to soils have utilized poliovirus as the model system. in the present study, comparative adsorption of a number of different types and strains of human enteroviruses and bacteriophages to nine different soil types was studied. under the experimental conditions of this study, greater than 90% of all viruses adsorbed to a sandy loam ... | 1979 | 42350 |
| hydrolysis of organophosphate insecticides by an immobilized-enzyme system. | an enzyme preparation that could detoxify parathion and eight other organophosphate pesticides was covalently bound to either porous glass or porous silica beads. this immobilized-enzyme system was examined for its use in detoxification of pesticides in production wastewaters. the kinetics of parathion hydrolysis were examined at flow rates up to 96 liter/hr and at influent substrate concentrations ranging from 10--250 mg/liter. the enzyme reactor was able to hydrolyze 95% or more of the parathi ... | 1995 | 42449 |
| early identification, differentiation and treatment of ovarian neoplasia. | among 3205 patients who needed major gynecologic operations, only 250 (7.8%) had significant ovarian cysts or tumors (170 benign, 38 "low malignant potential," 42 gross cancers). contrary to prior reports, this study show that most patients with ovarian neoplasia had had some symptoms (duration ranged from two weeks to ten years), or a palpable adnexal mass or both. associated symptoms have been itemized in categories. procrastination by patients, after occurrence of the first symptoms, resulted ... | 1995 | 42571 |
| antimicrobial activity of amniotic fluid obtained vaginally. | twenty-nine amniotic fluid samples were aspirated from pregnant women at term (38-40 weeks' gestation) by tapping the bulging membrane vaginally, and their effects on escherichia coli, staphylococcus aureus and candida albicans were studied. inhibition rates were 72.41% for e coli, 68.96% for s aureus and 79.31% for c albicans. two samples (6.90%) affected only a single organism, 18 (62.07%) affected two organisms and eight (27.59%) affected all three. only one sample (3.45%) had no inhibitory e ... | 1979 | 42590 |
| an evaluation of 12 methods for the demonstration of penicillinase. | twelve methods for the demonstration of bacterial penicillinase production by strains of haemophilus influenzae and staphylococcus aureus are compared, and their suitability for routine clinical laboratory use is evaluated. the acidometric agar plate method is recommended. | 1979 | 42650 |
| beta-blocking drugs in hypertension. | 1995 | 42863 | |
| quantitative analysis of proton-linked transport systems. glutamate transport in staphylococcus aureus. | 1. the magnitude of the protonmotive force in respiring staphylococcus aureus was measured over the range of extracellular ph from 5.6 to 7.8. 2. the membrane potential remains constant at 150 mv, inside-negative, but the ph gradient decreases from 2.1 units, inside-alkaline, at ph 5.6 to zero at ph 7.5 and above. 3. the accumulation of glutamate in the soluble cell pool is ph-independent at a value equivalent to 100 mv. 4. the results of experiments studying co-transport of protons are consiste ... | 1979 | 43145 |
| [beta blockaders and sports]. | 1994 | 43247 | |
| nonlinear dependence of biological activity on hydrophobic character: the bilinear model. | in homologous series of compounds biological activity is linearly dependent on hydrophobic character until a cut-off point is reached where this linear relationship changes to a nonlinear relationship: biological activity increases with increase of hydrophobic character, reaches a maximum and then decreases with further increase of hydrophobic character. drug transport in biological systems is determined by the rate constants of transfer of the drug through aqueous and organic compartments. in s ... | 1979 | 43264 |
| opsonic activity of normal human cerebrospinal fluid for selected bacterial species. | the opsonic activity of normal human cerebrospinal fluid (csf) has not been well defined. in this study, the opsonic activity of normal csf for laboratory and blood culture isolates of staphylococcus aureus, streptococcus pneumoniae, escherichia coli, hemophilus influenzae type b, and neisseria meningitidis was measured by a quantitative assay employing radiolabeled bacteria and polymorphonuclear leukocytes. all isolates of s. aureus, except the wood 46 strain, were opsonized in undiluted csf (> ... | 1979 | 43289 |
| effects of blood on blood culture medium. | the morphological and biochemical changes that occur after inoculation of sterile blood into a blood culture medium (tryptic soy broth) with sodium polyanetholesulfonate and co(2) were investigated. cellular changes, ph, pco(2), and po(2) were monitored and evaluated. erythrocytes became crenated and developed precipitated hemoglobin inclusions within 4 h. the lymphocytes appeared morphologically intact at 24 h, and by 48 h a few cells had undergone transformation. many neutrophils were vacuolat ... | 1979 | 43336 |
| on an in vitro method of simulating drug release from viscous eye drops. | 1979 | 43382 | |
| cryptolepine hydrochloride effect on staphylococcus aureus. | 1979 | 43386 | |
| [fluorescent probe study of staphylococcal cell wall charges]. | the effect of ph and mgcl2 concentration on the fluorescence of 1-anilinonaphthalene-8-sulfonate (ans), an anion probe, was studied in suspensions of staphylococcus aureus. the maximum of ans fluorescence shifted towards the short wavelength region of the spectrum and its intensity increased when the cells were incubated in the medium with low ph and high ionic strength. the results are discussed in terms of electrostatic interactions between the anions of the probe and the negative space charge ... | 1979 | 43463 |
| some characteristics of staphylococcus aureus (penicillin-sensitive and -resistant groups) isolated from healthy individuals (nsukka, nigeria). | 1979 | 44164 | |
| symposium on health aspects of nonionizing radiation. the subcommittee on public health aspects of energy of the committee on public health of the new york academy of medicine. | 1994 | 44209 | |
| statistico epidemiological study of changes in the vaginal flora of contraceptive pill users in alexandria. | a stratified random sample of 1000 women with proportionate allocation according to district of residence was taken from normal females living in alexandria, egypt, and attending family planning centers in order to understand social-pathological changes in the vaginal flora of oral contraceptive (oc) users. cases were examined over 18 months, and all cases were given a combined oc. bacteriology and ph changes in vaginal flora were determined after 18 months. results of the bacteriological exa ... | 1979 | 44312 |
| evaluation of phagocytic and bactericidal activities of neutrophil granulocytes. determination of viable extracellular bacteria by their incorporation of 14c-leucine and 3h-thymidine. | a method for evaluation of human neutrophil granulocyte function based on the combined determination of total and extracellular bacteria is described. the total number of surviving bacteria is assessed by the determination of colony forming units (cfu) after hypotonic lysis of granulocytes. extracellular viable bacteria can be determined by the incorporation of 14c-leucine or 3h-thymidine into bacterial macromolecules since there is a linear relationship between macromolecular synthesis and bact ... | 1979 | 44387 |
| [hydrotherapy pools, microbiological and chemical results (author's transl)]. | the results of microbiological and chemical examinations of water samples collected from hydrotherapy pools for non incontinent patients proved that the officially agreed parameters for the surveillance of public swimming pools (osterr. bäderhygiene-gesetz and verordnung) have to be extended to meet the requirements of epidemiology. similarly the requirements for treatment and operating conditions of those waters should be more rigorous. minimal requirements for the treatment of water in hydroth ... | 1979 | 44417 |
| [bacteriological studies of the intestinal content of aquatic birds, fishes, and frogs with special reference to the presence of non-cholera vibrios (ncv) (author's transl)]. | in a screening study of surface waters, the authors were successful in culturing ncv in 2/3 of cases. since these organisms are incapable of multiplication in open waters and yet were present in water samples in considerable amounts, it was postulated that they persisted in certain forms of aquatic life. to elucidate this question, the intestinal contents and in some cases, the bile of a total of 110 animals belonging to 17 different bird, fish, and frog species from different habitata were exam ... | 1979 | 44627 |
| human monocyte killing of staphylococcus aureus: modulation by agonists of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate. | this study was designed to test whether cyclic nucleotides play a role in the regulation of bacterial killing by human monocytes. agents were tested for their ability to activate monocyte adenylate or guanylate cyclase in cell-free preparations, to increase cyclic adenosine 3',5'-monophosphate (camp) or cyclic guanosine 3',5'-monophosphate (cgmp) in intact human monocytes, and to modulate monocyte-induced killing of staphylococcus aureus in vitro. prostaglandin e1 and cholera toxin activated mon ... | 1979 | 44704 |
| [hypothalamic hypophyseotropic hormones: biochemical and clinical aspects. ii. somatostatin, corticoliberin, melanoliberin, malanostatin, prolactostatin, prolactoliberin]. | 1994 | 44746 | |
| comparative study of erythromycin, amoxicillin and ampicillin antimicrobial activity against human respiratory tract pathogens. | an in vitro test system was used to compare the antimicrobial activity of erythromycin, amoxicillin and ampicillin against respiratory tract pathogens isolated from man. the minimum inhibitory concentrations (mics) of fresh clinical isolates of streptoccus pyogenes, streptocuccus pneumoniae, staphylococcus aureus and haemophilus influenzae to the macrolide and penicillins ranged between 0.01 and 0.9 microgram/ml. the microbes were exposed to each antibiotic for approximately 3 h at 1x,2x and 5x ... | 1979 | 44765 |
| [animal experiments with combined local immunization against an influenza virus disease (author's transl)]. | 1979 | 44774 | |
| a simple method of detecting staphylococcal hemolysins. | a modification of the "one-plate method" for detection of staphylococcal hemolysins has been described. bacterial strains of staphylococcus aureus, streptococcus agalactiae and cornebacterium pseudotuberculosis were replaced by their prepurified hemolytically active exosubstances: beta-toxin, camp-factor, and, the exosubstance of corynebacterium pseudotuberculosis called corex. by means of the modification described, exact detection of hemolysins in possible with staphylococcal strains producing ... | 1979 | 44782 |
| cefaclor: clinical and bacteriological evaluation in 45 cases. | this report deals with studies of the effectiveness, tolerance and toxicity of cefaclor in the treatment of 45 patients with urinary tract infections (40 cases) and pneumonia (5 cases) caused by susceptible pathogens. cefaclor was administered orally in a dosage of 1 to 3 g per day for 7 to 11 days. clinical and laboratory examinations were performed before, during, at the end of treatment, and 4 weeks later in cases of urinary infection. all 5 patients with pneumonia and bronchopneumonia were c ... | 1979 | 44909 |
| [improved method for the demonstration of protein a of staphylococcus aureus (author's transl)]. | protein a (pa) could be extracted completely from staphylococcus aureus by treatment with concentrated formic acid. this led to the development of a semi-quantitative determination of pa by hemagglutination (fig. 1). the treatment with formic acid yielded pa more effectively than the commonly used extraction by boiling (table 1). it could be conducted directly on a loopfull of staphylococci obtained from blood agar. it required no additional cultivation in a fluid medium. most suitable for the h ... | 1979 | 44938 |