Publications

comparison of the rim-h rapid identification kit with conventional tests for the identification of haemophilus spp.	a commercially available system, the rim-h system (austin biological laboratories, austin, tex.), was evaluated for its ability to rapidly and accurately identify various haemophilus spp. a total of 110 clinical isolates were tested by both the rim and conventional identification procedures. the rim agreed with the standard identification for 100% of the haemophilus influenzae (76 of 76) and 92.0% of the haemophilus parainfluenzae (23 of 25) isolates tested. the identifications of haemophilus pa ...	1990	2203817
free radical ablation prevents ischemic injury after long periods of cold storage in rat pancreas transplantation.		1990	2219357
evaluation of a selective medium for the isolation and differentiation of haemophilus influenzae and haemophilus parainfluenzae from the respiratory tract of chronic bronchitics.	respiratory tract specimens from chronic bronchitic patients were cultured for haemophilus species on conventional chocolate agar and a modified sucrose medium in order to determine the accuracy of the new medium in differentiating haemophilus influenzae from haemophilus parainfluenzae strains. haemophilus influenzae biotypes ii and iii and haemophilus parainfluenzae biotypes i and ii were found to be the predominant strains isolated from the respiratory tract. the modified sucrose medium was fo ...	1990	2243729
purification and characterization of an outer membrane protein adhesin from haemophilus parainfluenzae hp-28.	outer membranes were isolated from haemophilus parainfluenzae hp-28 by a mild extraction method followed by sephadex g-150 gel filtration chromatography. the first peak (pool 1) recovered contained an activity which inhibited adherence of hp-28 cells to saliva-coated spheroidal hydroxyapatite. sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) of pool 1 revealed a dominant protein band of 34 kda. the sds-page-purified 34-kda protein was excised from the gel and used for antibod ...	1990	2254013
lymphoid dendritic accessory cells of the rat.	the expression of mhc class ii antigens on potential apc is a crucial step in t-lymphocyte activation and the initiation of an immune response. the studies which are presented here were initiated to characterize the critical apc present in physiologically normal, untreated rats. such a cell should constitutively express these antigens at high density and therefore provide the apparatus necessary to provoke both primary and secondary immune responses at any time. dac were found to fulfill these c ...	1990	2258188
[the role of bacteria on facial rosacea-like dermatitis in adult type atopic dermatitis].	to investigate the role of bacteria on facial rosacea-like dermatitis lesion in adult type atopic dermatitis, we measured the numbers of bacteria on the skin, nasal and pharyngeal surface of each individual, and then examined its sensitivity to antibiotics. the numbers of bacteria on the surface of skin increased according to the severity of skin eruption. staphylococcus aureus was detected from the skin and nasal surface more than pharyngeal surface. bacteria on the pharyngeal surface were both ...	1990	2259005
[basic and clinical studies on norfloxacin in the pediatric field].	pharmacokinetic , bacteriological and clinical studies on norfloxacin (nflx), a quinolone-carboxylic acid antibacterial agent, were conducted in the pediatric field. 1. serum concentrations and urinary excretion of nflx after single dose of 2.2 approximately 5.6 mg/kg (mean 4.4 +/- 1.2 mg/kg) were determined in 13 children with ages between 6 and 11 years. the mean peak serum concentration of the drug was 0.37 +/- 0.20 micrograms/ml at 2 hours after administration. the mean half-life of the drug ...	1990	2262968
unconsciousness associated with midazolam and erythromycin.	an 8-yr-old boy suffering from an asymptomatic ventricular septal defect was given erythromycin for antibiotic prophylaxis before adenoidectomy. sixty minutes after premedication with oral midazolam 0.5 mg kg-1 and oral atropine 0.03 mg kg-1, an infusion of erythromycin 400 mg was started. when 200 mg of erythromycin had been infused, the patient lost consciousness, but other vital functions remained normal. after 45 min, he awakened spontaneously. at the time the plasma concentration of midazol ...	2007	2265054
mast cell activation in sterile bladder and prostate inflammation.	sterile inflammation of the bladder has often been associated with interstitial cystitis (ic), a urologic condition of unknown etiology, predominantly affecting young and middle-aged females, for which no effective therapy is known. recent reports have indicated that ic is associated with an increased number of bladder mast cells. here we report the case of a middle-aged man with chronic sterile hematuria, dysuria and lower abdominal pain associated with a high number of bladder and prostate mas ...	1990	2276845
do real dos practice manipulation?		2008	2276931
effect of amoxycillin/clavulanic acid on the aerobic and anaerobic tonsillar microflora in the treatment of recurrent tonsillitis.	30 patients with recurrent tonsillitis were treated with amoxycillin/clavulanic acid (500 mg/125 mg) t.i.d. for 10 days. the most often isolated potential aerobic pathogenic bacteria were staphylococcus aureus, streptococcus milleri and haemophilus parainfluenzae. group a streptococci were isolated from 7 patients. anaerobic cocci and bacteroides species were the dominating anaerobic bacteria isolated from the tonsils. tonsillar cultures were taken before antibiotic treatment started, on days 11 ...	1990	2284575
high-performance liquid chromatography of retinoids in blood.		2008	2292964
[prosthetic valve endocarditis caused by haemophilus parainfluenzae].	a case of endocarditis preceded by dental treatment without prophylactic antibiotics and caused by haemophilus parainfluenzae in a patient with a biological heart valve prosthesis is described. this bacteria grows slowly in the usual blood culture media and, because of this, the etiological diagnosis was not established until after incubation for 11 days. blood cultures from patients suspected of having endocarditis should be incubated for longer than the usual five to seven days. close cooperat ...	1990	2301053
haemophilus influenzae and h. parainfluenzae as urinary pathogens.	two cases are described, one of haemophilus influenzae urinary infection in a female with no past history of urinary tract infection (uti) and the other of haemophilus parainfluenzae infection in a male with a renal calculus. haemophilus spp. are rare urinary pathogens and these cases are even more unusual because h. influenzae uti has almost always previously been found in either children or adult males, while h. parainfluenzae uti has only been reported once before.	1990	2319146
haemophilus parainfluenzae bacteremia associated with a pacemaker wire localized by gallium scan.	a young woman with a history of sick sinus syndrome and placement of a permanent pacemaker 6 months before admission had fever and haemophilus parainfluenzae bacteremia. a gallium scan localized the infection to the site of the pacemaker wire. echocardiograms were negative for any vegetations. the patient responded to cefotaxime and trimethoprim-sulfamethoxazole therapy. we believe that this is the first case of h. parainfluenzae bacteremia associated with a pacemaker wire and localized by galli ...	1990	2341266
naturally occurring nad-independent haemophilus parainfluenzae.	four, nad-independent, clinical isolates of haemophilus parainfluenzae were recovered from a genital ulcer, a purulent skin lesion, a sputum specimen and a throat swab respectively. with the exception of nad requirement, the strains exhibited the biochemical characteristics of h. parainfluenzae biotype ii. the genetic relationship between these isolates and a standard strain of h. parainfluenzae was determined by testing transforming activities of two chromosomal markers, streptomycin resistance ...	1990	2384741
[isolation of modification-restriction enzymes hpai and hpaii].	a method for simultaneous isolation of four enzymes of modification-restriction of dna from haemophilus parainfluenzae is proposed. the properties of hpai and hpaii dna-methylases were investigated.	1985	2416355
[papillary endothelial hyperplasia. diagnosis and differential diagnosis].	there are only a few reports of papillary endothelial hyperplasia in the literature. familiarity with the entity is important for the differential diagnosis of vascular tumors. the authors analyzed seven cases of papillary endothelial hyperplasia morphologically. characteristic features include intravascular, endothelial-covered, papillary formations of varying size. cellular atypia, pathologic mitotic figures and necrosis were absent. the presence of a single-layered endothelium and uniform cel ...	1980	2425509
[sudeck syndrome and its "psychosomatic disposition": a comparative clinico-psychologic study of the etiology in accident patients].	this study comprises a large psychological investigation of 10 patients with posttraumatic sympathetic dystrophy of hands and compares the results with a control-group. it was found that a "psychosomatic disposition" with three factors completing each other occurs: a neurotic-depressive structure of personality including narcisistic problems, a posttraumatic disorder of adaptation with various emotional traits (as a reaction to the stress of the somatic trauma) and finally a less confidential st ...	2008	2474840
[haemophilus parainfluenzae in an adult].		1989	2490472
histamine synthesis by respiratory tract micro-organisms: possible role in pathogenicity.	five bacterial species considered to be potential pathogens in acute exacerbations of chronic bronchitis, cystic fibrosis, and pneumonia--branhamella catarrhalis, haemophilus parainfluenzae, pseudomonas aeruginosa, staphylococcus aureus and streptococcus pneumoniae--were evaluated for their potential to synthesise histamine in vitro. bacterial species commonly isolated from infected sputum but generally not considered to be pathogenic--enterobacteriacae, neisseria pharyngis, coagulase negative s ...	1989	2499609
v-factor (nad) independent haemophilus parainfluenzae recovered from a human genital ulcer.		1989	2504602
comparative evaluation of cefuroxime axetil and cefaclor for treatment of acute bacterial maxillary sinusitis.	cefuroxime axetil, a new beta-lactamase-stable cephalosporin, was compared with cefaclor for the treatment of acute bacterial maxillary sinusitis in 106 adult patients. direct sinus aspirations for quantitative bacterial culture were done for all patients before treatment; aspiration was repeated for most patients after treatment. pretreatment sinus aspirates were positive for 63 of 134 sampled sinuses. of specimens yielding at least 10(4) cfu/ml, haemophilus influenzae (38%) and streptococcus p ...	1989	2510772
distribution of haemophilus influenzae and haemophilus parainfluenzae biotypes isolated from the human genitourinary tract.	a total of 3,598 genital specimens from men and women was cultured for haemophilus spp. using a simple selective culture method. two hundred and thirty three samples (6.5%) were positive for haemophilus spp., 216 haemophilus parainfluenzae and 28 haemophilus influenzae strains being isolated. biotyping demonstrated that haemophilus parainfluenzae biotype ii was dominant at all sites, especially the male urethra, comprising 59% of all haemophilus strains isolated. on the other hand, haemophilus i ...	1989	2513194
[the psychology of the tuberculosis patient in different historical periods and its repercussions in social life, art and customs].		2008	2519493
[laboratory and clinical studies on clarithromycin in the field of pediatrics].	laboratory and clinical studies on clarithromycin (te-031, a-56268), a new macrolide antibiotic, were carried out in the field of pediatrics. the results obtained are summarized as follows: 1. serum concentrations, urinary concentrations and urinary recovery rates were determined upon oral administration on fasting of te-031 at doses of 5 mg/kg granules in 1 case and tablets in 2 cases, and 10 mg/kg granules in 1 and 15 mg/kg granules in 1. peak serum levels were obtained at 30 minutes in 2 case ...	1989	2526245
[laboratory and clinical studies of clarithromycin in pediatric fields].	we have carried out laboratory and clinical studies on clarithromycin (te-031, a-56268). the results are summarized as follows. serum and urinary concentrations of te-031 were determined in 5 children with ages between 6 and 11 years given single oral doses of 5, 6.7, 10 and 15 mg/kg. serum concentrations peaked at 1 hour after administration of 5, 6.7 and 15 mg/kg, and respective peak values were 1.98 micrograms/ml, 2.21 micrograms/ml and 5.58 micrograms/ml. biological half-lives for the drug a ...	1989	2526248
[clinical study of clarithromycin, a new macrolide antibiotic, in children].	1. clarithromycin (te-031, a-56268) was given orally to 46 children with respiratory infections, skin infections and others. a total of 9 patients were excluded; 8 patients refused to take the drug because of it's taste, and 1 patient was later found to have viral pneumonia. clinical efficacy was therefore evaluated in remaining 37 cases and was good or excellent in 27 cases. 2. bacteriologically, haemophilus influenzae strains isolated from 4 patients were eradicated in 1 and decreased in 3, re ...	1989	2526249
fetal arrhythmias: etiology, diagnosis, pathophysiology, and treatment.	the study of arrhythmias enables the clinician not only to treat and effectively prevent some types of fetal morbidity, but also to understand the normal human fetal physiology. it can be anticipated that the study of arrhythmias in the fetus will expand, if the work currently performed in the child and adult is any indication.	1989	2528209
the size and a physical map of the chromosome of haemophilus parainfluenzae.	the physical map of the haemophilus parainfluenzae chromosome is circular and approx. 2340 kb in circumference. the size of the map was determined by digesting agarose-immobilized chromosomes with the restriction enzymes, noti (gcggccgc), rsrii (cggatccg) and apai (gggccc), and using field-inversion gel electrophoresis to resolve the resulting fragments. the enzymes digest the h. parainfluenzae genome into 7, 10, and 18 fragments, respectively. the map order of the fragments was obtained by usin ...	1989	2555271
introduction of transposon tn916 dna into haemophilus influenzae and haemophilus parainfluenzae.	enterococcus (streptococcus) faecalis transposon tn916 was introduced into haemophilus influenzae rd and haemophilus parainfluenzae by transformation and demonstrated to transpose efficiently. haemophilus transformants resistant to tetracycline were observed at a frequency of approximately 3 x 10(2) to 5 x 10(3)/micrograms of either pam120 (pgl101::tn916) or pam180 (pam81::tn916) plasmid dnas, which are incapable of autonomous replication in this host. restriction enzyme analysis and southern bl ...	1989	2556369
[clinical studies on cefpodoxime proxetil dry syrup in the field of pediatrics].	cefpodoxime proxetil (cpdx-pr, cs-807) dry syrup was administered orally to 31 patients with various infections at daily dose levels between 5.4 and 10.9 mg/kg divided into three doses. 1. the subjects were 3 patients with urinary tract infections, 25 with tonsillitis and 1 patient each with bronchitis, pneumonia, and cervical lymphadenitis. clinical effects were excellent in 16 cases, good in 14, and fair in 1 (tonsillitis), with an overall efficacy rate of 96.8%. 2. organisms suspected as path ...	1989	2562790
patients with neuroleptic malignant syndrome histories: what happens when they are rehospitalized?	among approximately 1450 patients treated with neuroleptics in a short-term psychiatric hospital, there were no cases of the neuroleptic malignant syndrome (nms). six patients with histories of nms were treated, either with nonneuroleptic therapies or with low doses of low-potency antipsychotic agents. no case of nms developed, but one patient suffered transient subsyndromal signs while treated briefly with loxapine. staff education, screening for patients with history of nms, and detection of e ...	2008	2565897
the pharmacology of segmental transmission in the spinal cord.		2008	2573110
are ecg welsh cup electrodes effectively cleaned?	re-usable welsh electrocardiograph (ecg)-electrodes are potential vehicles for cross infection. this study confirmed that in-use ecg-electrodes are frequently contaminated with organisms such as coagulase-negative staphylococci and gram-negative bacilli. the efficacy of five cleaning procedures was evaluated. immersing the electrodes in water at 60 degrees c for one hour was the most effective method of decontamination tested, following challenge with a standardised suspension of staphylococcus ...	1989	2575631
histophotometric quantification of the field effect and the extended field effect of tumors.	histophotometric investigations have been made on samples of human skin. fresh frozen serial sections were fixed and stained for either reactive protein thiols (pshr) or total reactive protein sulphur (trps) using modifications of the ddd-fast blue b-method. in addition, total protein thiols (psht) were stained with the mercurochromcyanide-method, and proteins were stained using a modified amido-black procedure. significant differences were found between the different tumours investigated and no ...	1989	2583544
typing of urogenital, maternal, and neonatal isolates of haemophilus influenzae and haemophilus parainfluenzae in correlation with clinical source of isolation and evidence for a genital specificity of h. influenzae biotype iv.	over a period of 6 years, 114 strains of haemophilus influenzae and haemophilus parainfluenzae were isolated from genital, mother-infant, or neonatal infections. their serotypes, biotypes, antibiotic resistance phenotypes, and outer membrane protein (omp) electrophoretic patterns were characterized and correlated with the various clinical outcomes. genital h. influenzae and h. parainfluenzae appeared to behave mostly as opportunistic pathogens; for instance, 62% of the cases of endometritis or p ...	1989	2584379
histamine production by haemophilus.	eight haemophilus influenzae and four haemophilus parainfluenzae strains, all freshly isolated from patients, were examined for histamine production. histamine was produced by all the h. influenzae (0.06 microgram-2.6 micrograms/100 ml) and by two of the h. parainfluenzae strains (46.5-47.9 micrograms/100 ml). it is concluded that histamine which plays an important role in the pathogenesis of chronic aspecific respiratory diseases, may derive not only from degranulation of mast cells, but also p ...	1989	2603641
flow distribution in human and canine tracheobronchial airway casts.	measurements of flow rates through hollow casts of human and canine tracheobronchial airways, which extend from just below the larynx to airways 1 mm in diameter, show basic similarities in the distribution of air flow and also species differences which must be considered. the distribution of air flow, for both constant and pulsatile inspiratory flow, was measured for minute volumes equivalent to 6, 11, 17 and 22 l min-1 for the human and 3, 6, 8, and 11 l min-1 for the dog. inertia of air flow ...	1989	2606683
incidence of selected ureolytic bacteria in human dental plaque from sites with differing salivary access.	saliva is the main source of urea in the human mouth and may be responsible for the predilection of ureolytic bacteria for certain tooth sites. as a test of this hypothesis, the ureolytic bacteria, haemophilus parainfluenzae, actinomyces naeslundii, actinomyces viscosus and coagulase-negative oral staphylococci, were enumerated in supragingival plaque from various sites in each of 10 subjects. the sites sampled included the maxillary and mandibular incisors (chosen because the lower incisors are ...	1989	2610614
characterization of the outer-membrane proteins of haemophilus parainfluenzae expressed under iron-sufficient and iron-restricted conditions.	sds-page of the outer-membrane (om) proteins of haemophilus parainfluenzae p205 grown under iron-sufficient conditions revealed three major proteins of 40, 37 and 13 kda. in addition, growth under conditions of iron-restriction resulted in the expression of at least four iron-repressible om proteins (iromps) of 72, 81, 88 and 90 kda. om proteins of 40 and 13 kda were non-covalently associated with peptidoglycan and were resistant to digestion with trypsin. a 38 kda peptidoglycan-associated prote ...	1989	2614387
percentage glycosylated haemoglobin in normal, g6pd deficient and hbss saudi arabs.	reference values have been established for erythrocyte glycosylated haemoglobin levels in a normal saudi population and in subjects with various haematological disorders. the mean glycosylated haemoglobin levels (se) were 7.28% (0.039) for normal, 6.04% (0.057) for g6pd deficient, 4.40% (0.081) for homozygous sickle cell, and 6.44% (0.109) for heterozygous sickle cell subjects. values of 6.26% (0.103) and 4.75% (0.127) for glycosylated haemoglobin were determined for heterozygous and homozygous ...	2008	2615585
perception and mindset in the innovative leader.		2009	2627913
experiences with required and elective didactic courses--suny/health science center at stony brook.		2008	2629984
nutrition teaching in medical schools.		2008	2629987
a clinico-pathologic presentation. mucoepidermoid carcinoma.		2008	2630610
a clinico-pathologic presentation. mucoepidermoid carcinoma.		2008	2630610
[aspects of the popular attitude about diarrhea among tswana-speaking urbanites].	this article contains a general overview of cultural perceptions of diarrhoeal disease amongst infants as expressed by tswana-speaking urbanites. attention is mainly given to the perception of gastro-enteritis. the research on which this article is based was concluded during 1984. the article indicates that a majority of respondents maintains the view that aetiologically it is possible to distinguish between three categories of illness, viz. illness of sorcery, illness of the shades or ancestors ...	2008	2632096
partial purification and characterization of alpha-glucosidase from rothia dentocariosa.	disaccharidases of oral bacteria, especially alpha-glucosidase and beta-fructofuranosidase, are considered to play an important role in the induction of dental caries. upon the examination of disaccharidases from several strains of saccharolytic oral bacteria, we found all of those bacteria to be capable of hydrolyzing the glycosidic linkage of sucrose. one species of bacteria, rothia dentocariosa, was found to contain a single disaccharidase, alpha-glucosidase. this enzyme was partially purifie ...	1989	2635358
[treatment of behçet's syndrome with colchicine].	the aim of the present study was to investigate the usefulness of colchicine in the treatment of behçet's syndrome. ten patients suffering from behçet's syndrome were selected for this purpose. the patients were treated with 1 mg/day of colchicine associated with 1 mg of betametasone during the initial florid phase of the disease. after the acute phase, betametasone was withdrawn. the patients were observed for a period ranging from 5 to 23 months. biochemical and immunological parameters were m ...	2007	2640046
comparison of genital and respiratory carriage of haemophilus parainfluenzae in men.	in the first study, genital carriage of haemophilus parainfluenzae was investigated in 103 women and 292 men attending a clinic for genitourinary medicine. in a second study, pairs of urethral and throat swabs were studied in 279 men. the vaginal carriage was 2%, urethral 12.4% and throat 13.3%. biotype 2 was found to be a genital type and throat carriage of this biotype was significantly associated with its concomitant urethral carriage. biotypes 1 and 3 were mainly found in the throat. biotype ...	1989	2644431
crouzon's syndrome associated with acanthosis nigricans: ramifications for the craniofacial surgeon.	crouzon's syndrome is one of many disorders that have been associated with acanthosis nigricans. previously reported cases documenting this association have been reviewed, and additional cases that have been treated at the institute of reconstructive plastic surgery at new york university medical center have been added. recommendations for the surgical management of this unique group of patients are presented.	2008	2650599
[haemophilus influenzae and haemophilus parainfluenzae: etiologic agents of sexually transmitted diseases?].	in 573 urethral swabs, 3 haemophilus influenzae (hi) and 7 haemophilus parainfluenzae (hpi) were isolated; 7 of the patients had clinical features of urethritis and in 3 another genital pathogen was associated. biotype iv was the predominant one in hi, and ii in hpi. in 6.259 endocervical and/or vaginal swabs 15 hi and 5 hpi were isolated. three out of the 15 females infected by hi, had clinical features of salpingitis and 8 of vaginitis; 5 of them were carriers of an iud. in four out of the 5 f ...	1989	2654517
acute transverse myelopathy complicating systemic lupus erythematosus.	a sixteen year old girl with systemic lupus erythematosus developed acute transverse myelopathy. she was treated with high dose steroids, cyclophosphamide, and plasma exchange and regained partial neurological function. previous descriptions of transverse myelopathy complicating systemic lupus erythematosus are reviewed, with particular reference to the efficacy of high dose steroid treatment.	2006	2662918
[clinical studies on sulbactam/ampicillin in the field of pediatrics].	during 8 months from october 1986 to may 1987, the clinical efficacy of sulbactam/ampicillin (sbt/abpc) was evaluated in 63 pediatric inpatients with various infections. clinical efficacies were evaluable in 58 patients among them (consisting of 2 patients with sepsis, 3 with tonsillitis, 12 with bronchitis, 6 with bronchopneumonia, 24 with pneumonia, 1 with phlegmon, 2 with lymphadenitis, 1 with impetigo and 7 with urinary tract infection) and were excellent in 40 patients and good in 17 with a ...	1989	2664249
[studies on sulbactam/ampicillin in the field of pediatrics].	pharmacokinetic and clinical studies on sulbactam/ampicillin (sbt/abpc) were carried out in the field of pediatrics. 1. absorption and excretion serum levels and urinary excretion of sbt/abpc were studied in 4 children with ages 6 to 8 years. the mean serum concentration of sbt at 15 minutes following a single intravenous injection of 30 mg/kg of sbt/abpc was 27.4 +/- 2.2 micrograms/ml and that of abpc was 42.8 +/- 3.9 micrograms/ml, and their concentrations declined with mean half-lives of 1.06 ...	1989	2664250
[clinical evaluation of sulbactam/ampicillin in children].	sulbactam/ampicillin (sbt/abpc), a combination at a fixed ratio of abpc and sbt which is an irreversible inhibitor of beta-lactamase in a 2:1 ratio, was clinically evaluated for its efficacy and safety in 24 patients with ages from 5 month-old to 12 years old with bacterial infection. the results obtained are summarized as follows. 1. a pharmacokinetic study following 30 mg/kg sbt/abpc administration by 30 minutes drip infusion or intravenous bolus injection showed that mean half-lives of sbt an ...	1989	2664251
isolation and biochemical characterization of haemophilus species isolated simultaneously from the oropharyngeal and anogenital areas.	several reports have described the high frequency of pharyngeal isolation of haemophilus species. few studies have compared the simultaneous isolation rate of this species in the oropharyngeal and anogenital areas. using two selective media, heart infusion agar (hia) supplemented with 5% defibrinated rabbit blood, 1% isovitalex, and either bacitracin alone (100 micrograms/ml) or bacitracin (5 micrograms/ml), vancomycin (3 micrograms/ml), and polymyxin b (1 microgram/ml), we isolated haemophilus ...	1989	2671014
is the cyclosporin a toxicity on rat pancreatic b-cells modulated by the mhc?	high cyclosporin a doses (50 mg/kg b.w.) were given male wistar rats either homozygous for rt1a or rt1u. both rat strains are characterized by a similar diminished body weight gain. cyclosporin a exerted in both strains an increased fed plasma glucose, decreased glucose tolerance and diminished pancreatic insulin content, however, the wistar rat strain with the mhc rt1u was more sensitive to the effect of cyclosporin a, indicated by a more marked alteration of pancreatic b-cells and a delayed re ...	1989	2673814
computer simulations of globular protein folding and tertiary structure.	in summary, although a large number of disparate techniques have been applied to predict the tertiary structure of globular proteins from their amino acid sequence, the solution is not yet at hand. methodologies for predicting the conformation of constrained, small protein fragments appear to be successful. as the size of the system increases, the level of detail of the treatment decreases; approaches that employ very detailed potentials appear to be limited to about 30-40 residues. although thi ...	2008	2688673
resistance to third generation cephalosporins: the current situation.	newer beta-lactam antibiotics, notably the third generation cephalosporins (3 gc) have been designed for providing high intrinsic potency against a large variety of microorganisms. bacterial resistance can occur however, and nowadays, clinicians are concerned by novel situations where even most recently developed compounds can be ineffective. a first situation is generated by bacteria which produce great amounts of chromosomal cephalosporinase. the resistance emerges during therapy, in hospital ...	2009	2689351
[clinical studies on cefixime in pediatrics].	clinical usefulness of cefixime (cfix), a new oral cephalosporin antibiotic, in pediatric field was investigated. the results obtained were summarized as follows. 1. the clinical efficacy of cfix was investigated in a total of 138 children including 49 with upper respiratory tract infections (rti), 22 with acute bronchitis, 18 with pneumonia, 19 with scarlet fever and 21 with urinary tract infections (uti). 2. clinical effectiveness was excellent in 58, good in 60, fair in 14 and poor in 3, with ...	1989	2693753
normal-tissue tolerance to fast-neutron teletherapy.		2009	2697654
chronic hip pain and limp in a 3-year-old girl.		2008	2704930
chronic hip pain and limp in a 3-year-old girl.		2008	2704930
some geometric properties of the third metacarpal bone: a comparison between the thoroughbred and standardbred racehorse.	geometric properties of the third metacarpal bone were compared between the young and adult standardbred and thoroughbred racehorse. the change in shape during growth and superimposed training was dramatic in both breeds but the thoroughbred showed the greatest difference in the minimum moment of inertia as the animal matured. males had larger moments of inertia throughout the length of the diaphysis than did females. the differences in geometric properties of the third metacarpal bone between t ...	1989	2708392
management of acute asthma.		2009	2713796
sore point.		2009	2721956
extraterrestrial amino acids in cretaceous/tertiary boundary sediments at stevns klint, denmark.	since the discovery nearly a decade ago that cretaceous/tertiary (k/t) boundary layers are greatly enriched in iridium, a rare element in the earth's crust, there has been intense controversy on the relationship between this ir anomaly and the massive extinction of organisms ranging from dinosaurs to marine plankton that characterizes the k/t boundary. convincing evidence suggests that both the ir spike and the extinction event were caused by the collision of a large bolide (greater than 10 km i ...	2009	2725679
a smile for the möbius' syndrome patient.	a major problem for the patient with möbius' syndrome is the inability to smile. with the development of vascularized muscle transplantation, the possibilities for improved facial animation were explored. muscle transplantation was carried out in 7 patients; innervation was provided by the hypoglossal nerve, the motor nerve to the masseter muscle, or in 1 patient a transfacial nerve graft. in this article the technical aspects of the procedure as well as the results are described in detail.	2009	2735718
influence of food on relative bioavailability of fluoride in man from na2fpo3-containing tablets for the treatment of osteoporosis.	aqueous solutions of naf and sodium monofluorophosphate (na2fpo3, mfp) and tablets containing mfp (caflu, tridin) were given as single oral doses to fasting healthy volunteers in an intra-individual crossover study. serum fluoride (f) levels and urinary f concentrations were measured using an f-ion-sensitive electrode; 8 h profiles of f concentrations in serum and 24 h urinary f output were determined. f availability and pharmacokinetic data were identical for all items. in a second group of exp ...	1989	2737790
[bacteriological, pharmacokinetic and clinical studies of sulbactam/ampicillin in the pediatric field].	the usefulness of sulbactam/ampicillin (sbt/abpc) in the treatment of pediatric infections was evaluated. 1. twenty pediatric patients with infection were treated with sbt/abpc and an intravenous dosage of 27.8-47.4 mg/kg, 3 to 4 times a day. clinical efficacies in 18 patients excluding 2 patients of mycoplasma pneumonia (9 cases of pneumonia, 6 urinary tract infection, 1 tonsillitis, 1 maxillary sinusitis and 1 osteomyelitis) were judged to be excellent in 13 patients and good in 5. there was n ...	1989	2746851
neonatal graves disease.		2009	2753558
balloon test occlusion of the internal carotid artery with stable xenon/ct cerebral blood flow imaging.		2009	2753650
[construction and testing of a strain gauge for measuring masticatory force].	the main objective of this study was to establish and test a measuring system for monitoring occlusal forces and force cycles during mastication. a measuring module using strain gauge transducers was incorporated in the bridge-pontic of a three part test bridgework. a load cell was used intraorally for loading and calibration. the test bridges were incorporated in the patient's mouth and calibrated in vivo using variable loads. the recording system was a special intensifying and processing syste ...	2009	2772595
disposal of epidural catheter stylets: taming the snake.		2009	2774246
subaortic stenosis associated with anomalous right ventricular muscle bundle and ventricular septal defect.	a rare case of biventricular outflow tract obstruction in the form of discrete subaortic membrane and hypertrophic anomalous right ventricular muscle bundle associated with ventricular septal defect is presented.	2009	2777307
the prevalence of development defects of enamel and dental caries in new zealand children receiving differing fluoride supplementation, in 1982 and 1985.	seven hundred and twenty-seven 9-year-old children resident in hawke's bay were examined in 1985, 3 years after a baseline survey of a cohort of the same age group. children were allocated to one of four fluoride-history groups on the basis of the responses of parents to a questionnaire, which also gave information on infant feeding and household water source. examination conditions were duplicated, and children were examined by the same examiner using a modification of the dde index. the preval ...	2009	2783769
clinical evaluation of propofol as an intravenous anaesthetic agent in cats and dogs.	the clinical efficacy and safety of an emulsion containing 10 mg/ml of the intravenous anaesthetic propofol were evaluated in cats and dogs by veterinary surgeons in eight practices in the united kingdom. a total of 290 dogs and 207 cats were anaesthetised with propofol either as a single injection for procedures of short duration, or as an induction agent with maintenance provided by further incremental injections or as an induction agent with maintenance by gaseous agents. the mean induction d ...	1989	2783794
risk factors for cervical cancer in greenland and denmark: a population-based cross-sectional study.	the incidence of cervical cancer in greenlandic women aged 20-39 years is nearly 6 times higher than in danish women of the same age. possible determinants of cervical cancer incidence were investigated in a population-based cross-sectional study. from nuuk (greenland) and nykøbing falster (denmark) a sample of 800 women aged 20-39 years was drawn at random. a total of 586 and 661 women were studied in greenland and denmark, respectively. all underwent a personal interview. in greenland, 13% of ...	2009	2787295
[clinical and pharmacokinetic study on cefodizime, a new cephalosporin antibiotic, in the pediatric infections].	cefodizime (thr-221, cdzm), a new cephalosporin antibiotic, was evaluated for its safety and efficacy in 27 children with various bacterial infections. the episodes of infections included pneumonia (6 cases), bronchopneumonia (11 cases), lung abscess (1 case), acute pharyngitis (2 cases), cervical lymphadenitis (1 case), infected cephalohematoma (1 case), urinary tract infection (1 case), sepsis (2 cases) and purulent meningitis (2 cases). cdzm was effective in all but one, and its efficacy rate ...	1989	2795854
[clinical experience with cefodizime in bacterial infection of children].	clinical studies were performed on cefodizime (thr-221, cdzm), a new cephem antibiotic as described below. cdzm was administered to 13 patients in dose levels ranging from 55 to 96 mg/kg/day t.i.d. for 3-7 days (5.5 days on average). these patients included 8 with pneumonia, 2 with tonsillitis, 1 each with bronchitis, phlegmon and urinary tract infection. the overall efficacy rate was 92.3%, i.e., efficacy was excellent in 8, good in 4 and poor in 1. bacteriological efficacy was 83.3%, i.e., 5 s ...	1989	2795862
corneal icterus resulting from stromal bilirubin deposition.	three pairs of donor corneas were noted to be stained yellow after dissection from the whole globe. the peripheral cornea was stained more intensely than the central cornea in each case. all three of the donors had had jaundice with elevated serum bilirubin levels for at least 1 month before death. the corneas were finely minced and eluted in chloroform for a period of at least 1 week. scleras from two of the three donors were similarly treated. spectrophotometric analysis of the corneal and scl ...	2010	2797724
occult polymicrobial endocarditis with haemophilus parainfluenzae.		1989	2801745
[diagnosis, differential diagnosis and management of fetal ovarian cysts--experiences in 9 cases].		2010	2802696
total gastrectomy and oesophagojejunostomy with linear stapling devices.	when performing total gastrectomy and oesophagojejunostomy with a circular stapling device two disadvantages are obvious; firstly, a purse-string suture is needed, and secondly the instrument can be extremely difficult to introduce if the oesophagus is narrow, so that the risk of rupture is substantial. we therefore developed the following technique. when the specimen is attached only to the oesophagus, and the roux-en-y loop has already been divided with a linear stapling device, a small incisi ...	2009	2804585
the fiscal blind spot in psychotherapy.		1989	2808069
antimicrobial susceptibilities of haemophilus species in hong kong.	altogether 403 haemophilus spp. were isolated in seven hospital laboratories in hong kong during june 1986, mostly from sputum. of these 73% were haemophilus influenzae and 27% haemophilus parainfluenzae. all the isolates of h. influenzae were non-capsulated; haemophilus spp. were not isolated from blood or cerebrospinal fluid (csf) during the period of the study. antimicrobial resistance, including multiple resistance, was common. of all the strains of h. influenzae, 20% were resistant to 1 mg/ ...	1989	2809236
[laboratory and clinical studies on cefteram pivoxil in the field of pediatrics].	laboratory and clinical studies on cefteram pivoxil(cefteram) a new cephem antibiotic, were carried out in the field of pediatrics. the results obtained are summarized as follows: 1. serum concentrations, urinary concentrations and urinary recovery rates of cefteram (cftm) were determined upon oral administration after meal of cefteram pivoxil (cftm-pi) at doses of 3 mg/kg granules in 2 cases and 6 mg/kg granules in 2. peak serum levels of cftm were obtained at 3 hours in 2 cases and 4 hours in ...	1989	2810748
[clinical studies on cefteram pivoxil granules in pediatrics].	a newly developed cephalosporin, cefteram pivoxil (cftm-pi, t-2588), was evaluated clinically in 40 patients. a pharmacokinetic study was also performed with 8 patients. cftm-pi was administered as granules. one patient was given cftm-pi at a dose of 1.5 mg/kg, each of 3 patients was given the drug at a dose of 3 mg/kg and each of 4 patients at a dose of 6 mg/kg. in most cases, serum concentrations of cftm were determined at 2, 3, 4, and 6 hours after dosing. urinary concentrations of cftm were ...	1989	2810757
[clinical studies of cefteram pivoxil in pediatrics].	the clinical efficacy and the safety of cefteram pivoxil granule (cftm-pi, t-2588), a newly prepared drug for pediatric use, were performed. a total of 60 patients with ages between 6 months and 14 years 3 months with pediatric infections were medicated with cftm-pi at dose levels of 3.2-9.9 mg/kg 3 times daily for 3-11 days. clinical responses to the drug were excellent in 3 of 3 patients with acute pharyngitis, excellent in 14, good in 5 and poor in 2 of 21 patients with acute purulent tonsill ...	1989	2810758
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
[intraoperative monitoring of cerebral function and carotid hemodynamics during carotid endarterectomy].	the authors investigated the hemodynamics and monitored the cerebral function to perform the carotid endarterectomy (cea) safely. the hemodynamics were investigated by measurements of carotid arterial blood flow by an electromagnetic flow meter before and after cea. and a doppler flow meter applied directly to the carotid arteries to analyze the flow parameters such as peak frequencies (pf), mean frequencies (mf), mode frequencies (mo f) and % window. we used routinely our specially designed shu ...	2009	2812257
identification of an additional sendai virus non-structural protein encoded by the p/c mrna.	peptide antiserum and monoclonal antibodies have detected a previously unrecognized small non-structural protein in sendai virus-infected cells. this protein, designated x, appears to represent the c-terminal 95 amino acids of the p protein reading frame. the x protein appears to be almost as abundant as the p protein on a molar basis in vivo. no evidence of a precursor-product relationship between the x and p proteins could be found.	1987	2821189
enhanced capacity for release of leucotriene b4 by neutrophils in rheumatoid arthritis.	the calcium dependent metabolism of endogenous arachidonic acid (aa) was investigated in 17 patients with rheumatoid arthritis during treatment with dextropropoxyphene alone and in 25 healthy volunteers. incorporation of [1-14c]aa into intracellular phospholipids of purified neutrophils was achieved by incubation until steady state before activation with ionophore a23187. analysis of extracellular metabolites was performed by extraction, thin layer chromatography, autoradiography, and laser dens ...	2010	2821934
identification and affinity labeling of very high affinity binding sites for the phenylalkylamine series of ca+ channel blockers in the drosophila nervous system.	the interaction of putative ca2+ channels of drosophila head membranes with molecules of the phenylalkylamine series was studied from binding experiments using (-)-[3h]d888 and (+/-)-[3h]verapamil. these ligands recognize a single class (kd = 0.1-0.4 nm; bmax = 1600-1800 fmol/mg of protein) of very high affinity binding sites. the most potent molecule in the phenylalkylamine series was (-)-verapamil with a kd value as exceptionally low as 4.7 pm. molecules in the benzothiazepine and diphenylbuty ...	1999	2827725
signal-dependent translocation of simian virus 40 large-t antigen into rat liver nuclei in a cell-free system.	an in vitro nuclear translocation system is described in which isolated rat liver nuclei were incubated in a defined buffered medium containing radiolabeled or fluorescently labeled exogenous proteins. the nuclei were rapidly recovered, extracted, and analyzed for the presence of associated radiolabeled or fluorescently labeled proteins. the isolated nuclei exhibited the same specificity for protein uptake as seen previously in vivo, accumulating simian virus 40 wild-type large-t antigen and p53 ...	1987	2830486
isolation of haem-bearing peptides of haem proteins by the use of adsorption chromatography.		1987	2832428
high-performance liquid chromatographic separation and immunological characterization of soluble bovine viral diarrhea virus antigen.	sodium dodecyl sulphate-polyacrylamide gel electrophoresis and western blot analysis of the protein extracts from bovine viral diarrhea virus (bvdv, singer strain) infected primary calf testicle cells (soluble antigen) showed the presence of four virus specific polypeptides of 105, 90, 84 and 67 kilodaltons (kd) the 84-kd being the most abundant. anion-exchange high-performance liquid chromatography (hplc) of soluble antigen separated the virus specific polypeptides in individual peaks while the ...	1988	2832429
vector-mediated dna double-strand break repair analysis in normal, and radiation-sensitive, chinese hamster v79 cells.	dna double-strand break repair was assessed in 2 new radiation-sensitive v79 hamster cell lines (irs1 and irs2) by their ability to rejoin restriction endonuclease cuts in a transferred selectable sv40--e. coli gpt recombinant gene. the studied gene was carried in the vector ppmh16 which also contained a second selectable hsvtk-neo recombinant gene which acted as a control for dna transformation. the parental v79 cells showed correct rejoining of kpni and ecorv double-strand breaks in approximat ...	2010	2834642